55510 Federal Register / Vol. 73, No. 187 / Thursday, September 25, 2008 / Notices 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–8718–3; Docket ID No. EPA–HQ–ORD– 

2008–0245] 

Draft Toxicological Review of Ethylene 

Glycol Mono Butyl Ether (EGBE): In 

Support of the Summary Information in 

the Integrated Risk Information System 

(IRIS) 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice of Peer Review 

Workshop. 

SUMMARY: EPA is announcing that 

Eastern Research Group, Inc. (ERG), an 

EPA contractor for external scientific 

peer review, will convene an 

independent panel of experts and 

organize and conduct an external peer 

review workshop to review the external 

review draft document titled, 

‘‘Toxicological Review of Ethylene 

Glycol Mono Butyl Ether (EGBE): In 

Support of Summary Information on the 

Integrated Risk Information System 

(IRIS)’’ (EPA/635/R–08/006A). EPA 

previously announced the 60-day public 

comment period (ending June 24, 2008) 

for the draft document in the Federal 

Register on April 25, 2008 (73 FR 

22372–22373). EPA will consider public 

comments and recommendations from 

the expert panel workshop as EPA 

finalizes the draft document. 

The public comment period and the 

external peer review workshop are 

separate processes that provide 

opportunities for all interested parties to 

comment on the document. EPA intends 

to forward public comments submitted 

in accordance with the Federal Register 

notice (73 FR 22372–22373) to ERG for 

consideration by the external peer 

review panel prior to the workshop. 

EPA is releasing this draft document 

solely for the purpose of predissemination peer review under 

applicable information quality 

guidelines. This document has not been 

formally disseminated by EPA. It does 

not represent and should not be 

construed to represent any Agency 

policy or determination. 

The public may attend this workshop 

as observers through a registration 

process, and time will be set aside for 

observers to give brief oral comments at 

the workshop regarding the draft 

document under review. The draft 

document and EPA’s peer review charge 

are available via the Internet on NCEA’s 

home page under the Recent Additions 

and the Data and Publications menus at 

http://www.epa.gov/ncea. When 

finalizing the draft document, EPA 

intends to consider the comments and 

recommendations from the external peer 

review workshop and any public 

comments that EPA receives in 

accordance with 73 FR 22372–22373, 

April 25, 2008. Public comments 

submitted during the 60-day public 

comment period ending June 24, 2008, 

may be observed at http:// 

www.regulations.gov under Docket ID 

No. EPA–HQ–ORD–2008–0245. 

DATES: The peer review workshop will 

begin on October 16, 2008, at 

approximately 8:30 a.m. and end at 

approximately 5 p.m., Eastern time. 

Observers must register by Thursday, 

October 9, 2008. Indicate at the time of 

registration if you wish to make brief 

oral comments at the workshop. 

ADDRESSES: The peer review workshop 

will be held at the Environmental 

Protection Agency, 109 T.W. Alexander 

Dr., RTP, NC 27709. ERG is organizing, 

convening, and conducting the peer 

review workshop. To attend the 

workshop as an observer, register by 

Thursday, October 9, 2008, via the 

Internet at https://www2.ergweb.com/ 

projects/conferences/peerreview/ 

register-egbe.htm. You may also register 

by e-mail at meetings@erg.com (subject 

line: EGBE Workshop), by phone: 781– 

674–7374 or toll free at 800–803–2833, 

or by faxing a registration request to 

781–674–2906 (please reference the 

‘‘EGBE Peer Review Workshop’’ and 

include your name, title, affiliation, full 

address and contact information). 

The draft ‘‘Toxicological Review of 

Ethylene Glycol Mono Butyl Ether 

(EGBE): In Support of Summary 

Information on the Integrated Risk 

Information System (IRIS)’’ is available 

via the Internet on the National Center 

for Environmental Assessment’s (NCEA) 

home page under the Recent Additions 

and the Data and Publications menus at 

http://www.epa.gov/ncea. A limited 

number of paper copies are available 

from NCEA’s Technical Information 

Staff, telephone: 703–347–8561; 

facsimile: 703–347–8691. If you are 

requesting a paper copy, please provide 

your name, mailing address, and the 

document title. Copies are not available 

from ERG. 

FOR FURTHER INFORMATION CONTACT: For 

information on the peer review 

workshop, contact ERG, 110 Hartwell 

Avenue, Lexington, MA 02421–3136; 

telephone: 781–674–7374; facsimile: 

781–674–2906; or e-mail: 

meetings@erg.com (subject line: EGBE). 

If you have questions about the 

document, contact Angela Howard, 

National Center for Environmental 

Assessment, (B–243–01), U.S. EPA, 109 

T.W. Alexander Dr. RTP, NC 27709; 

telephone: 919–541–5133; facsimile: 

919–541–0245; or e-mail: 

howard.angela@epa.gov. 

SUPPLEMENTARY INFORMATION: 

I. Summary of Information About the 

Integrated Risk Information System 

(IRIS) 

IRIS is a database that contains 

potential adverse human health effects 

information that may result from 

chronic (or lifetime) exposure to specific 

chemical substances found in the 

environment. The database (available on 

the Internet at http://www.epa.gov/iris) 

contains qualitative and quantitative 

health effects information for more than 

540 chemical substances that may be 

used to support the first two steps 

(hazard identification and doseresponse evaluation) of a risk 

assessment process. When supported by 

available data, the database provides 

oral reference doses (RfDs) and 

inhalation reference concentrations 

(RfCs) for chronic health effects, and 

oral slope factors and inhalation unit 

risks for carcinogenic effects. Combined 

with specific exposure information, 

government and private entities can use 

IRIS data to help characterize public 

health risks of chemical substances in a 

site-specific situation and thereby 

support risk management decisions 

designed to protect public health. 

II. Workshop Information 

Members of the public may attend the 

workshop as observers, and there will 

be a limited time for oral comments 

from the public. Pre-registration is 

strongly recommended as space is 

limited, and registrations will be 

accepted on a first-come, first-served 

basis. The deadline for pre-registration 

is October 9, 2008. If space allows, 

registrations will continue to be 

accepted after this date, including onsite registrations. Time will be set aside 

to hear comments from observers, and 

individuals will be limited to a 

maximum of five minutes during the 

morning session of peer review 

workshop. Please let ERG know if you 

wish to make comments during the 

workshop by registering on the Web site 

at https://www2.ergweb.com/projects/ 

conferences/peerreview/registeregbe.htm and indicating your intent to 

make oral comments. 

Dated: September 16, 2008. 

Peter W. Preuss, 

Director, National Center for Environmental 

Assessment. 

[FR Doc. E8–22538 Filed 9–24–08; 8:45 am] 

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