alea-institute/kl3m-data-sample-004-shuffled huggingface dataset:
<PAGE>

                                                                     Exhibit 4.5

                                  FORM 51-102F3
                             MATERIAL CHANGE REPORT



ITEM 1   NAME AND ADDRESS OF COMPANY

         Neurochem Inc. ("Neurochem")
         275 Armand-Frappier Blvd.
         Laval, Quebec
         H7V 4A7


ITEM 2   DATE OF MATERIAL CHANGE

         February 23, 2005


ITEM 3   NEWS RELEASE

         A press release was disseminated by Canada Newswire on February 23,
         2005 from Montreal, Quebec.


ITEM 4   SUMMARY OF MATERIAL CHANGE

         Neurochem announced that it has filed a short form preliminary
         prospectus with the Canadian securities regulators and a registration
         statement with the U.S. Securities and Exchange Commission in
         connection with an offering of its common shares (the "Offering").


ITEM 5   FULL DESCRIPTION OF MATERIAL CHANGE

         The Offering will consist of a new issue of 4,000,000 common shares of
         Neurochem. UBS Investment Bank will be acting as the sole book running
         underwriter in this Offering, and CIBC World Markets Inc., Piper
         Jaffray, BMO Nesbitt Burns Inc., Desjardins Securities Inc., Fortis
         Securities LLC and Wells Fargo Securities will be acting as
         co-managers.

         The net proceeds from the Offering will be used to fund Neurochem's
         clinical trials of its investigational product candidates, primarily
         Alzhemed(TM), as well as to further complete pre-clinical and research
         and development programs and the balance for the marketing of
         Fibrillex(TM), working capital and general corporate purposes.


ITEM 6   RELIANCE ON SUBSECTION 7.1(2) OR (3) OF NATIONAL INSTRUMENT 51-102

         This report is not being filed on a confidential basis.



<PAGE>

ITEM 7   OMITTED INFORMATION

         N/A


ITEM 8   EXECUTIVE OFFICER

         For further information, please contact Lise Hebert, Vice-President,
         Corporate Communications, at 450.680.4572.


ITEM 9   DATE OF REPORT

         February 28, 2005



                                   (signed) David Skinner
                                   ---------------------------------------------

                                   David Skinner
                                   General Counsel and Corporate Secretary
EXHIBIT 31.2
                              CERTIFICATION

I, David T. Nguyen, certify that:

1.  I have reviewed this quarterly report on Form 10-QSB of Portsmouth Square,
Inc.;

2.  Based on my knowledge, this quarterly report does not contain any untrue
statement of a material fact or omit to state a material fact necessary to make
the statements made, in light of the circumstances under which such statements
were made, not misleading with respect to the period covered by this report;

3.  Based on my knowledge, the financial statements and other financial
information included in this report, fairly present in all material respects
the financial condition, results of operations and cash flows of the registrant
as of, and for, the periods presented in this report;

4.  The registrant's other certifying officer(s) and I are responsible for
establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e)) for the registrant and have:

    a) designed such disclosure controls and procedures, or caused such
disclosure controls and procedures to be designed under our supervision, to
ensure that material information relating to the registrant, including its
consolidated subsidiaries, is made known to us by others within those entities,
particularly during the period in which this report is being prepared;

    b) evaluated the effectiveness of the registrant's disclosure controls and
procedures and presented in this report our conclusions about the effectiveness
of the disclosure controls and procedures, as of the end of the period covered
by this report based on such evaluation; and

    c) disclosed in this report any change in the registrant's internal control
over financial reporting that occurred during the registrant's most recent
fiscal quarter that has materially affected, or is reasonably likely to
materially affect, the registrant's internal control over financial reporting;
and

5.  The registrant's other certifying officer(s) and I have disclosed, based on
our most recent evaluation of internal control over financial reporting, to the
registrant's auditors and the audit committee of registrant's board of
directors (or persons performing equivalent functions):

    a) all significant deficiencies and material weakness in the design or
operation of internal control over financial reporting which are reasonably
likely to adversely affect the registrant's ability to record, process,
summarize and report financial information; and

    b) any fraud, whether or not material, that involves management or other
employees who have a significant role in registrant's internal control over
financial reporting.

Date: May 15, 2006                            /s/ David T. Nguyen
                                              ---------------------------
                                              David T. Nguyen, Treasurer
                                              and Controller (serving as
                                              Chief Financial Officer)
Exhibit 32.1.1  Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of
2002
(Subsections (a) and (b) of Section 1350, Chapter 63
of Title 18, United States Code)  Pursuant to Section 906
of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of
section 1350, chapter 63 of title 18, United States Code), each of
the undersigned officers of Osiris Therapeutics, Inc., (the Company),
does hereby certify, to the best of each officers knowledge that:  The Annual Report on Form 10-K
for the year ended December 31, 2008 (the Form 10-K) of the Company
fully complies with the requirements of Section 13(a) and 15(d) of
the Securities Exchange Act of 1934, and the information contained in the Form 10-K
fairly presents, in all material respects, the financial condition and results
of operations of the Company.  Date: March 16, 2009
  /s/ C. Randal MillsC. Randal Mills, Ph.D.Chief Executive OfficerDate: March 16, 2009
  /s/ Richard W. HuntRichard W. HuntChief Financial Officer  A signed original of this
written statement required by Section 906 has been provided to the Company
and will be retained by the Company and furnished to the Securities and
Exchange Commission or its staff upon request. This certification accompanies
the Form 10-K to which it relates, is not deemed filed with the SEC and is
not to be incorporated by reference into any filing of the Company under the
Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as
amended (whether made before or after the date of the Form 10-K),
irrespective of any general incorporation language contained in such filing.
##### 



EXHIBIT 32(a)

CERTIFICATION OF PERIODIC REPORT
PURSUANT TO 18 U.S.C. SECTION 1350 (AS ADOPTED PURSUANT TO SECTION 906 OF
SARBANES-OXLEY ACT OF 2002)

I, Sherrill Stone, Chairman of the Board and Chief Executive Officer of
Peerless Mfg. Co. (the Company), certify, pursuant to 18 U.S.C. Section 1350
(as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002), that:



|(1) |  | The Quarterly Report on Form 10-Q of the Company for the period ended
December 31, 2003, as filed with the Securities Exchange Commission on
the date hereof (the Report) fully complies with the requirements of
Section 13(a) or 15(d) of the Securities Exchange Act of 1934, as
amended; and
|--- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|   
|(2) |  | The information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations
of the Company as of the dates and for the periods expressed in the
Report.                                                                                  

| |                          
| | -------------------------
| | /s/ Sherrill Stone       
| |                          
| | Sherrill Stone           
| | Chairman of the Board and
| | Chief Executive Officer  
| | Date: February 13, 2004
<TABLE> <S> <C>

<ARTICLE> 5
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                          NOV-28-1997
<PERIOD-END>                               FEB-28-1997
<CASH>                                              30
<SECURITIES>                                         0
<RECEIVABLES>                                     8855
<ALLOWANCES>                                       269
<INVENTORY>                                      11711
<CURRENT-ASSETS>                                 23169
<PP&E>                                           31921
<DEPRECIATION>                                   19844
<TOTAL-ASSETS>                                   39166
<CURRENT-LIABILITIES>                            16684
<BONDS>                                              0
<PREFERRED-MANDATORY>                                0
<PREFERRED>                                          0
<COMMON>                                          2030
<OTHER-SE>                                        5264
<TOTAL-LIABILITY-AND-EQUITY>                     39166
<SALES>                                          15284
<TOTAL-REVENUES>                                 15284
<CGS>                                            11488
<TOTAL-COSTS>                                    14627
<OTHER-EXPENSES>                                    76
<LOSS-PROVISION>                                     2
<INTEREST-EXPENSE>                                 336
<INCOME-PRETAX>                                    245
<INCOME-TAX>                                       104
<INCOME-CONTINUING>                                141
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                       141
<EPS-PRIMARY>                                      .06
<EPS-DILUTED>                                      .06
        

</TABLE>
#### Green L. J. Haralson and Wife, Plaintiffs in Error, *v.*David Bridges, Defendant in Error.

EEBOE TO JOHNSON.

A payment of rent made to a husband is a legal discharge of liability for rent to a wife, arising out of her estate; although they were living apart. The fact that husband and wife are living apart does not alter their legal rights in this respect.

This suit was brought in the Circuit Court of Johnson County, by Haralson and wife against Bridges, in assumpsit, for rent due and in arrear, on an agreement not under seal, for certain premises described in the declaration. The cause of action arose before the intermarriage of the plaintiffs ; the premises had been leased from Mrs. Haralson.

The cause was heard before Denning, Judge, at August term, 1852, of the Johnson Circuit Court.

J. Jack, for plaintiffs in error.

R. S. Nelson, for defendant in error.

Trumbull, J.

This was an action of assumpsit, by husband and wife, for the recovery of rent which arose out of the estate of the latter, and fell due before their intermarriage. The defendant pleaded payment to one Smith, who was, at the time, of the leasing and occupation of the premises and the receipt of the rent, the husband of the said Judith, the present Mrs. Haralson; the plaintiffs replied, that the payment was made by collusion, and to prevent them from receiving the rent as was their legal right, and alleged that the said Smith, at the time when, &c., and till the said Judith was subsequently divorced from him, was living notoriously separate and apart from her, *38having abandoned and wholly neglected to support her. To this replication there was a demurrer which the circuit court sustained, and that decision is now assigned for error.

We have no doubt that a payment made to Smith, while the husband of Judith, was a legal discharge of the defendant’s liability. The fact that he and his wife were then living apart did not alter their legal rights'in this respect. It may be that upon the state of case set forth in the replication, a court of equity would interfere to prevent the collection, by the husband, of the rents issuing out of the wife’s estate; but unless restrained in some such way, the lessee’s right to make payment to the husband is unquestioned.

*Judgment affirmed.*
Exhibit 32.1



CERTIFICATION



Pursuant to 18 U.S.C. § 1350, the undersigned officer of THE POTOMAC EDISON COMPANY (the Company), hereby certifies, to such
officers knowledge, that the Companys Quarterly Report on Form 10-Q for the quarter ended September 30, 2004 (the Report) fully complies with the requirements of Section 13(a) of the Securities Exchange Act of 1934 and
that the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.



|                 |  |                            
|---------------- |  | ---------------------------
|                 |  | /s/ Paul J. Evanson        
|                 |  | Paul J. Evanson            
|November 4, 2004 |  | Principal Executive Officer
<TABLE> <S> <C>

<ARTICLE> 5
<LEGEND>
   THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM THE
   BALANCE SHEET AND STATEMENT OF INCOME AND COMPREHENSIVE INCOME OF
   PORTSMOUTH SQUARE, INC. SET FORTH IN ITS FORM 10-QSB REPORT FOR THE
   QUARTERLY PERIOD ENDED SEPTEMBER 30, 1999 AND IS QUALIFIED IN ITS ENTIRETY
   BY REFERENCE TO SUCH 10-QSB REPORT.
</LEGEND>

<CIK> 0000079661
<NAME> PORTSMOUTH SQUARE, INC.

<S>                                      <C>
<PERIOD-TYPE>                                  9-Mos
<FISCAL-YEAR-END>                        DEC-31-1999
<PERIOD-START>                           JAN-01-1999
<PERIOD-END>                             SEP-30-1999
<CASH>                                         28062
<SECURITIES>                                 2415818
<RECEIVABLES>                                      0
<ALLOWANCES>                                       0
<INVENTORY>                                        0
<CURRENT-ASSETS>                             1557346
<PP&E>                                             0
<DEPRECIATION>                                     0
<TOTAL-ASSETS>                               5953001
<CURRENT-LIABILITIES>                        1190024
<BONDS>                                            0
<PREFERRED-MANDATORY>                              0
<PREFERRED>                                        0
<COMMON>                                     2092300
<OTHER-SE>                                   2583065
<TOTAL-LIABILITY-AND-EQUITY>                 5953001
<SALES>                                            0
<TOTAL-REVENUES>                             2747439
<CGS>                                              0
<TOTAL-COSTS>                                      0
<OTHER-EXPENSES>                              428024
<LOSS-PROVISION>                                   0
<INTEREST-EXPENSE>                             52077
<INCOME-PRETAX>                              2319415
<INCOME-TAX>                                  927766
<INCOME-CONTINUING>                          1391649
<DISCONTINUED>                                     0
<EXTRAORDINARY>                                    0
<CHANGES>                                          0
<NET-INCOME>                                 1391649
<EPS-BASIC>                                   1.90
<EPS-DILUTED>                                   1.90



</TABLE>
NOT FINAL UNTIL TIME EXPI RES TO FILE REHEARING MOTION AND, IF FILED, DETERMINED

IN THE DISTRICT COURT OF APPEAL

OF FLORIDA

SECOND DISTRICT

HENRY COBB, ) ) Appellant, ) ) v. ) Case No. 2D14-5793 ) STATE OF FLORIDA, ) ) Appellee. ) )

Opinion filed October 9, 2015.

Appeal from the Circuit Court for Manatee County; Charles E. Roberts, Judge.

Howard L. Dimmig, II, Public Defender, and Frank D. L. Winstead, Special Assistant Public Defender, Bartow, for Appellant.

Pamela Jo Bondi, Attorney General, Tallahassee, for Appellee.

PER CURIAM.

Affirmed. See Almond v. State, 89 So. 3d 1056, 1058 (Fla. 2d D CA 2012)

(holding that when a criminal c ourt still has jurisdiction over a defendant whose criminal

record mandates the court to classify him as a sexual predator, the criminal court may

designate the defendant as a sexual predator even though the de signation was- 2 - overlooked at sentencing many years earlier); Moore v. State, 8 80 So. 2d 826, 828-29

(Fla. 1st DCA 2004) (collecting cases).

LaROSE, KHOUZAM, and BLACK, JJ., Concur.
Exhibit (4)(xi)
     
     
     
     
     
     
     
     
     Ms. Debra Kream, Esq.
     Plymouth Rubber, Inc.
     104 Revere Street
     Canton, MA 02021
     
     Dear Deborah:
     
     This letter will serve to amend the Master Security Agreement dated as of
     December 29, 1995 by and between General Electric Capital Corporation
     ("Secured Party") and Plymouth Rubber Company ("Debtor") as follows:  
     
     1.   Section 10(a) is hereby amended to read as follows:
     
        (a) At all times during the term of the Security Agreement,      
        Debtor shall maintain; (I) Minimum Tangible Net Worth of a positive
        $4,500,000 plus 75% of Net Income until the maturity of all note(s),
        (ii) Minimum Working Capital of $3,000,000.00 for fiscal year 1997 and
        $3,750,000 for fiscal year 1998 and each fiscal year thereafter until
        the maturity of all note(s), (iii) Minimum Fixed Charge Coverage ratio
        of 1.25x to 1.0x for fiscal year 1997 and 1.50 x to 1.0x for fiscal
        year 1998 and each fiscal year thereafter until the maturity of all
        note(s), (iv) a maximum Total liabilities to Tangible Net Worth of
        6.0x to 1.0x until the maturity of all note(s).  "Tangible Net Worth"
        is defined as Stockholder's Equity less intangible assets, plus any
        FAS #87 after tax change for minimum pension obligations.  "EBITDA" is
        defined as earnings before Interest, Depreciation, Amortization and
        Taxes and Unrecognized Net Obligations at transition.  "Fixed Charges"
        is defined as current portion of long term debt, plus current portion
        of capital leases, plus interest expense, plus preferred dividends. 
        "Fixed Charge Coverage is defined as EBITDA divided by fixed charges
        (both determined on a rolling four quarter average).  "Total Debt"
        includes all liabilities of the Debtor as defined by GAAP. 
        Intangibles as used for the determination of Minimum Tangible Net
        Worth shall be defined by GAAP exclusive of the deferred tax asset and
        associated valuation reserve as defined by FAS 109.  Accounting terms
        used herein not otherwise defined herein shall be as defined, and all
        calculations hereunder shall be made, in accordance with GAAP.
     
      All other terms and conditions will remain in full force and effect.  The
      Amendment is effective beginning November 30, 1996.
     
                               
                                   Sincerely,
     
     
     
                                   Robert R. Blee
                                   Senior Credit Analyst
     
     AGREED AND ACKNOWLEDGED:
     
     PLYMOUTH RUBBER COMPANY
     
     By:                           
     
     Name:                         
     
     Title:                        
     
     Date:
Document Headings

                    Document headings vary by document type but may contain                    the following:                  
                -                       the agency or agencies that issued and signed a document                    
                -                       the number of the CFR title and the number of each part                      the document amends, proposes to amend, or is directly                      related to                    
                -                       the agency docket number / agency internal file number                    
                -                       the RIN which identifies each regulatory action listed in                      the Unified Agenda of Federal Regulatory and Deregulatory                      Actions                    

                    See the                                          Document Drafting Handbook                                        for more details.                  

###### Department of Health and Human Services

# ACTION:

Announcement of meeting.  

# SUMMARY:

This notice announces the 25th meeting of the American Health Information Community Electronic Health Records Workgroup in accordance with the Federal Advisory Committee Act (Pub. L. 92-463, 5 U.S.C., App.)  

# DATES:

September 10, 2008, from 1 p.m. to 4 p.m. [Eastern]  

# ADDRESSES:

Mary C. Switzer Building (330 C Street, SW., Washington, DC 20201), Conference Room 1114. Please use the C Street entrance closest to 3rd Street and bring photo ID for entry to a Federal building.  

# FOR FURTHER INFORMATION CONTACT:

*http://www.hhs.gov/​healthit/​ahic/​healthrecords/​.*

# SUPPLEMENTARY INFORMATION:

The Workgroup will continue its discussion on ways to achieve widespread adoption of certified EHRs, minimizing gaps in adoption among providers.  

                    The meeting will be available via Web cast. For additional information, go to:                     *http://www.hhs.gov/​healthit/​ahic/​healthrecords/​ehr_​instruct.html*.                  

Dated: August 13, 2008.  

Judith Sparrow,  

Director, American Health Information Community, Office of Programs and Coordination, Office of the National Coordinator for Health Information Technology.

[FR Doc. E8-20328 Filed 9-2-08; 8:45 am]  

BILLING CODE 4150-45-P