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                            Library & Multimedia
 Sequencing of full mitochondrial genomes for NIST population samples
NCJ Number
              302570
Journal

*Forensic Science International Genetics Supplement Series* Volume: 7 Issue: 1 Dated: 2019 Pages: 452-453
Author(s)
          K. M. Kiesler;
                        et al
Date Published

2019
Length
              2 pages
Annotation
              This article reports on a population sequencing study of 607 mitochondrial genomes (mtGenomes) undertaken by the U.S. National Institute of Standards and Technology in collaboration with the Armed Forces Medical Examiner System’s Armed Forces DNA Identification Laboratory.
Abstract
              The goal of the study is to increase the availability of high-quality whole mtGenome sequences for haplotype frequency estimations, enabling the increased discrimination power of the entire extranuclear genome to be used. Whole mtGenome sequencing is enabled by next generation sequencing workflows, which are vastly simplified compared to Sanger-type sequencing. The current article reports on an evaluation of the relative performance of mtGenome versus sequencing the control region of the mtGenome alone. (publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        DJO-NIJ-17-RO-0219


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Award
        Development of a Forensic Quality Mitogenome Haplotype Database from 5000 High Quality Samples Using Next-Generation Sequencing Methods
    
  
  
Date Published: January 1, 2019
    
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