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                            Library & Multimedia
 QuantAssure Cassette Development Research
NCJ Number
              239211

Author(s)
          Christian  Carson;
                        Peter  Sutovsky;
                        Glen  Ford;
                        Dale  Dembrow;
                        Joseph  Gorman
Date Published

2011
Length
              43 pages
Annotation
              This research examines the development of a lateral flow cassette to identify the presence of sperm and semen in evidence samples.
Abstract
              Results conclude that the effort to develop a polyclonal antibody by immunizing rabbits with the SPTRX3 exon5 peptide failed. The inability to develop SPTRX3 antibodies during the course of this project has prevented the intended effect of making the processing of rape kits in the forensic laboratory faster and more effective. BluePoint Bioscience immunized mice with the SPTRX3 exon1 peptide in order to develop a monoclonal antibody. This effort at SPTRX3 antibody development also failed. A second round of mouse immunizations met with the same fate. The inability to develop SPTRX3 antibodies brought the research project to a close. However, it is believed that the concept of developing a lateral flow cassette to determine the presence of spermatozoa and semen in evidence samples remains viable. Tables, figures, and references
      
  
          Additional Details
Grant Number(s)
        2008-IJ-CX-K007


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Report (Technical)


  
  
        
  Award
        Detection and quantitation of spermatozoa
    
  
  
Date Published: January 1, 2011
    
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        Forensic sciences
        Rape and sexual assault
        Rape evidence kits



  
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