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                            Library & Multimedia
 Surface-Enhanced Raman Spectroscopy for Trace Identification of Controlled Substances: Morphine, Codeine, and Hydrocodone
NCJ Number
              255354
Journal

*Journal of Forensic Sciences* Volume: 56 Issue: 1 Dated: Jan 2011 Pages: 200-207
Author(s)
          Vinesh Rana;
                        Maria V. Canamares;
                        Thomas Kubic;
                        Marco Leona;
                        John R. Lombardi
Date Published

January 2011
Length
              8 pages
Annotation
              This article reports on a research project that obtained the normal Raman and surface‐enhanced Raman spectrum of three controlled substances: morphine, codeine, and hydrocodone.
Abstract
              The spectra were assigned with the aid of density functional theory. Because of intense fluorescence, normal Raman spectra suffered from poor signal‐to‐noise, even when differential subtraction techniques were used. On the other hand, surface enhancement by Ag nanoparticles both enhanced the Raman signal and suppressed the fluorescence, enabling more sensitive detection and identification. The article also presents a set of discriminant bands, useful for distinguishing the three compounds despite the similarities in their structures. (publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        2006-DN-BX-K034


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Award
        Development of Advanced Raman Spectroscopy Methods and Databases for the Evaluation of Trace Evidence and the Examination of Questioned Documents
    
  
  
Date Published: January 1, 2011
    
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        Controlled substances



  
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