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                            Library & Multimedia
 The Simons Genome Diversity Project: 300 Genomes from 142 Diverse Populations
NCJ Number
              252320
Journal

*Nature* Volume: 538 Issue: 7624 Dated: October 2016 Pages: 201.-206
Author(s)
          Swapan  Mallick;
                        Heng  Li;
                        Mark  Lipson;
                        Iain  Mathieson;
                        Melissa  Gymrek;
                        Fernando  Racimo;
                        Mengyao  Zhao;
                        Ninj  Chennagin
Date Published

October 2016
Length
              6 pages
Annotation
              This article reports on the Simons Genome Diversity Project data set, which consists of high-quality genomes of 300 individuals from 142 diverse populations.
Abstract
              These genomes include at least 5.8 million base pairs that are not present in the human reference genome. The current analysis identified key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5 percent in non-Africans compared to Africans since divergence. This analysis shows that the ancestors of some pairs of present-day human populations were substantially separated by 100,000 years ago, well before the archaeologically attested onset of behavioral modernity. The analysis also indicates that indigenous Australians, New Guineans, and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. 45 references  (Publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        2014-DN-BX-K089


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)
                                Report (Study/Research)
                                Report (Grant Sponsored)
                                Program/Project Description


  
  
        
  Award
        Robust STR calling from High-throughput Sequencing Technologies
    
  
  
Date Published: October 1, 2016
    
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