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                            Library & Multimedia
 Population Data for a Novel, Highly Discriminating Tetra-Local Y-Chromosome Short Tandem Repeat: DYS503
NCJ Number
              241071
Journal

*Journal of Forensic Sciences* Volume: 52 Issue: 2 Dated: March 2007 Pages: 498-499
Author(s)
          Erin K. Hanson, M.S.;
                        Jack Ballantyne, Ph.D.
Date Published

March 2007
Length
              2 pages
Annotation
              During the construction of an annotated short tandem repeat (STR) physical map of the human Y chromosome, the authors identified a novel tetra-local locus, DYS503; the current study collected population data from male Caucasian-Americans (n = 980) and African-Americans (n = 100) in order to determine whether DYS503 exhibits an elevated diversity.
Abstract
              Thirty-three unique expanded genotypes were observed among the 198 male samples used in this study. The overall genotype diversity was determined to be 0.92 for the Caucasian-American population and 0.75 for the African-American population. Significant differences in the essentially bimodal genotype distributions were observed between the two populations. The most frequent genotype in Caucasian-Americans was 11-14-14-15 (20 percent of samples); whereas, 13-13-14-14 was the most common genotype observed in the African-American population (49 percent of samples). These findings further showed the significant stratification of the two populations obtained by DYS503 typing. Genotype diversity was higher in Caucasian-Americans (0.92) than in African-Americans (0.75). Population samples for gene-diversity studies were obtained from the Virginia Division of Forensic Science (blood stains). Procedures used in the testing are described. A table presents the genotype frequencies for DYS503 (expanded data) in the two populations, and another table presents allele sequences for DYS503. The complete dataset is available upon request. 2 tables and 5 references
      
  
          Additional Details
Grant Number(s)
        98-IJ-CX-K003


  
  
        
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        NIJ-Sponsored


  
  
        
  Publication Type
        Report (Study/Research)
    
  
  
Date Published: March 1, 2007
    
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