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                            Library & Multimedia
 Simple Reagent Storage in Polyester-Paper Hybrid Microdevices for Colorimetric Detection
NCJ Number
              252282
Journal

*Sensors and Actuators B: Chemical* Volume: 246 Dated: July 2017 Pages: 740-747
Author(s)
          Shannon T. Krauss;
                        Victoria C. Holt;
                        James P. Landers
Date Published

July 2017
Length
              8 pages
Annotation
              This article describes the development of polyester-paper hybrid microfluidic devices that use a fabrication method, compounded from the print, cut, and laminate (PCL) technique, which allows for simple yet effective dry reagent storage for improved use with centrifugal or polymeric-based devices.
Abstract
              A challenge in developing microfluidic devices for fully portable and automated field analyses is the ability to integrate and store reagents in a stable form while maintaining a low cost for the system. Paper-based field-deployable devices are currently the most extensively explored platforms for field use; however, centrifugal devices offer a means for heightened device automation and portability. The basis for many field devices is chemical sensing via colorimetric reactions. The current project used various proof-of-principle colorimetric assays for multiple applications, including the analysis of total protein, serum albumin, cocaine, 2,4,6-trinitrotoluene (TNT), and iron content. Localized reagent integration facilitated by paper punches allowed for both reagent stability prior to reaction for storage, color stability post-reaction for image analysis, and was compatible for multi-step analyses. Qualitative and quantitative results were achieved with the broad range of sample applications trialed here, while still maintaining the ability for downstream processing. (Publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        2015-R2-CX-0033


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)
                                Report (Study/Research)
                                Report (Grant Sponsored)
                                Program/Project Description


  
  
        
  Award
        Cost-Effective Printed Microfluidic Devices for Rapid Screening of Narcotics at the Point of Interdiction
    
  
  
Date Published: July 1, 2017
    
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