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                            Library & Multimedia
 Success Story: Forensic Epigenetics – Markers for the Identification of Body Fluids
NCJ Number
              304580

Date Published

April 2022
Annotation
              Since current methods used in operational forensic laboratories to identify body fluids lack sensitivity and specificity, this report presents the methodology and findings of a research project that produced markers and methods that can be applied to establishing the source identity of single and mixed biofluids at crime scenes.
Abstract
              Dr. Bruce McCord at Florida International University and colleagues at the University of Southern Mississippi are investigating the role of epigenetic modification in the characterization of various body fluids. Epigenetic modification refers to changes in gene expression not attributed to changes in genetic material. Dr. McCord has identified DNA methylation patterns and subsequently developed epigenetic methylation markers for the detection of various tissue types present in body fluids and dried stains recovered from crime scenes. A method that uses these markers was developed to provide clear quantitative results and has effectively distinguished between tissue types, with the added benefit of sample stability over time. The markers and methods from this research can be applied in establishing the source identity of single and mixed biofluids at crime scenes. This method provides for more specificity than currently used protein-based techniques, because cross-reactivity between body fluids is not an issue. Further, it fits with current DNA analysis methodology, enabling quick, easy interpretation.
      
  
          Additional Details
Grant Number(s)
        2016-MU-BX-K110
                                2011-DN-BX-K564


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)


  
  
        
  Award
        Forensic Science Training Development and Delivery Program
                                Forensic Technology Center of Excellence (FTCOE) FY17
    
  
  
Date Published: April 15, 2022
    
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        Body fluid analysis
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