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                            Library & Multimedia
 Suite of Aptamer-Based Sensors for the Detection of Fentanyl and Its Analogues
NCJ Number
              306943

Author(s)
          Juan Canoura;
                        Yingzhu Liu;
                        Jacob Perry;
                        Connor Willis;
                        Yi Xiao
Date Published

April 2023
Length
              11 pages
Annotation
              This article presents the development of a series of new aptamer-based assays and sensors that can detect fentanyl and fentanyl analogues.
Abstract
              Fentanyl and its analogues are potent synthetic opioids that are commonly abused and are currently the number one cause of drug overdose death in the United States. The ability to detect fentanyl with simple, rapid, and low-cost tools is crucial for forensics, medical care, and public safety. Conventional on-site testing options for fentanyl detection - including chemical spot tests, lateral-flow immunoassays, and portable Raman spectrometers - each have their own unique flaws that limit their analytical utility. Here, the authors have developed a series of new aptamer-based assays and sensors that can detect fentanyl as well as several of its analogues in a reliable, accurate, rapid, and economic manner. These include colorimetric, fluorescent, and electrochemical sensors, which can detect and quantify minute quantities of fentanyl and many of its analogues with no response to other illicit drugs, cutting agents, or adulterants - even in interferent-ridden binary mixtures containing as little as 1% fentanyl. Given the high performance of these novel analytical tools, the authors foresee the potential for routine use by medical and law enforcement personnel as well as the general public to aid in rapid and accurate fentanyl identification. (Published Abstract Provided)
      
  
          Additional Details
Grant Number(s)
        2019-DU-BX-0024
                                2019-R2-CX-0045


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)


  
  
        
  Award
        Electrochemical Aptamer-Based Sensor for Rapid Identification of Marijuana from Hemp
                                Electrochemical Aptamer-Based Sensor for Rapid Opioid Detection in Seized Substances
    
  
  
Date Published: April 1, 2023
    
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