SECURITIES AND EXCHANGE COMMISSION
                                 WASHINGTON, D.C.  20549


                                     FORM 10-Q



                      QUARTERLY REPORT UNDER SECTION 13 OR 15(d)
                        OF THE SECURITIES EXCHANGE ACT OF 1934



   For the Quarter Ended September 30, 2010       Commission File No. 001-10156



                          ORIGINAL SIXTEEN TO ONE MINE, INC.
                (Exact name of registrant as specified in its charter)



                   CALIFORNIA                            94-0735390
      (State or other jurisdiction of     (I.R.S. Employer Identification No.)
        incorporated or organization

                     Post Office Box 909, Alleghany, CA  95910
                      (Address of principal executive offices)


                                    (530) 287-3223
                            (Registrant's telephone number)
                                (including area code)

Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the past 12 months (or for such shorter period that the Registrant
was required to file such reports), and (2) has been subject to such filing
requirement for the past 90 days.

                        Yes:                       No:  x



As of September 30, 2010, 13,399,505 shares of Common Stock, par value $.03 per
share, were issued and outstanding.

<page>


                                   PART I

1.  FINANCIAL INFORMATION

                              Original Sixteen to One Mine, Inc.
                                 Condensed Balance Sheet
                           September 30, 2010 and December 31, 2009

                               September 30, 2010        December 31, 2009
ASSETS

Current Assets
   Cash                                  $      307              $   7,321
   Accounts receivable                       14,878                  3,711
   Inventory                                376,830                414,331
                                         ----------             ----------
     Total current assets                   392,015                425,363
                                         ----------             ----------

Mining Property
   Real estate and property rights
      net of depletion of $524,145          230,401                230,401
   Real estate and mineral property          47,976                345,330
                                         ----------             ----------
                                            278,377                575,731
                                         ----------             ----------
Fixed Assets at Cost
   Equipment                                925,243                925,243
   Buildings                                209,487                209,487
   Vehicles                                 255,128                255,128
                                         ----------             ----------
                                          1,389,858              1,389,858
Less accumulated depreciation            (1,316,927)           (1,303,866)
                                         ----------             ----------
     Net fixed assets                        72,931                 85,992
                                         ----------             ----------
Other Assets
   Bonds and misc. deposits                   7,962                  5,460
                                         ----------             ----------

     Total Assets                        $ 751,285             $1,092,546
                                         ==========             ==========

LIABILITIES & STOCKHOLDERS' EQUITY

Current Liabilities
   Accounts payable &
      accrued expenses                      772,187                648,434
Due to related party                        293,947                647,555
Notes payable due within one year              -                    58,700
                                         ----------             ----------
     Total Current Liabilities            1,066,134              1,354,689
                                         ----------             ----------
Long Term Liabilities
   Notes payable due after one year         97,236                  97,236
                                         ----------             ----------
     Total Liabilities                    1,163,370              1,451,925
                                         ----------             ----------

Stockholders' Equity
   Capital stock, par value $.03:
     30,000,000 shares authorized:
     13,399,505 shares issued and
     outstanding as of Sept. 30, 2010 and
     13,373,505 as of December 31, 2009     440,656                439,876
   Additional paid-in capital             2,063,202              2,005,282
   (Accumulated deficit)
      retained earnings                  (2,915,943)           (2,804,537)
                                         ----------             ----------
     Total Stockholders' Equity           (412,085)              (359,379)
                                         ----------             ----------
Total Liabilities and
  Stockholders' Equity                     $751,285             $1,092,546
                                         ==========             ==========


                              See Accompanying Notes

<page>

                  Original Sixteen to One Mine, Inc.
             Statement of Operations and Retained Earnings


                  Three Months Ending Sept. 30,    Nine Months Ending Sept. 30,
                             2010            2009           2010           2009
                           ------          ------          ------         -----
Revenues:
  Gold & jewelry sales     $  36,779   $   34,942   $     99,952   $    132,288
                           -----------   -----------      --------     --------
     Total revenues           36,779       34,942         99,952        132,288
                            -----------   -----------    --------      --------
Operating expenses:
  Salaries and wages            67,749     16,476         153,642        50,716
  Contract Labor                 9,311      8,286          32,130        30,777
  Telephone & utilities         21,588     11,424          57,707        32,585
  Taxes - property & payroll    10,193      (619)          31,021        17,573
  Insurance                     17,092        190          30,679           570
  Supplies                      22,307      2,923          70,498        10,681
  Small equipment & repairs      5,666      5,309          11,657        10,877
  Drayage                        8,340      2,829          23,238         8,647
  Corporate expenses             2,386      1,655           9,483         9,731
  Legal and accounting           2,000      3,223           4,972         3,542
  Compliance/Safety                267        587           1,428           967
  Depreciation & amortization    4,354      4,898          13,061        14,693
  Other expenses                 5,656      1,476          26,987         7,931
                           ----------   ----------        -------       -------
  Total operating expenses     176,909      58,657         466,503      199,290
                          ----------    ----------       --------      --------
Profit (Loss) from operations (140,130)   (23,715)        (366,551)    (67,002)

Other Income & (Expense):
  Other income (expense)      (24,847)   (179,281)        255,945     (222,249)
                         ----------    -----------       -------       --------
Profit (Loss) before taxes  (164,977)    (202,996)     (110,606)     (289,251)
                         ----------    -----------     ---------     ----------
Income tax benefit (expense)                              (800)        (800)
                         ----------    -----------     ---------     ----------
Net profit (loss)      $   (164,977) $   (202,996) $    (111,406)   $ (290,051)
                       ============    ===========     ==========    ==========

Basic and diluted (loss)
 earnings per share     $    (.01)   $        (.02)  $      (.01) $       (.02)
                      ============    ============      =========     =========
Shares used in the
calculation of net
(loss) income per share 13,399,505    13,373,505       13,399,505   13,373,505
                       ============    ===========      ==========  ===========


                              See Accompanying Notes

<page>


                      Original Sixteen to One Mine, Inc.
                           Statement of Cash Flows
         Nine Months Ended Sept. 30, 2010 and Sept. 30, 2009

                                             Nine Months Ended Sept. 30,
                                               2010                   2009
                                         --------------         --------------


Net profit (loss)                             $  (111,406)         $ (290,051)
  Cash Flows From Operating Activities:
     Depreciation and amortization                  13,061              14,693
     Gain on sale of asset                            -                    -
     (Increase)Decrease in
        accounts receivable                       (11,167)            (10,946)
     Decrease(Increase) in inventory                37,501             270,315
     (Increase)Decrease in other
       current assets                                   -                  -
     (Decrease) increase in accounts payable
       and accrued expenses                        123,753             230,703
    (Decrease) increase in short term notes      (412,308)           (357,045)

                                              ------------          ----------
  Net cash (used) provided by
     operating activities                        (360,566)            (142,331)
                                              ------------          -----------

Cash Flows From Investing Activities:

  Removal (addition) of mining claims              (2,646)          143,263
  Proceed from sale real estate                    300,000           -
  Other assets bonds misc. deposits                (2,502)             -
                                              -----------        -----------
  Net cash (used) provided by
    investing activities                           294,852           143,263
                                                -----------         -----------

Cash Flows From Financing Activities

   Increase (decrease) notes payable                     -                 -
  Proceeds from sale of common stock                    780                -
  Additional paid-in capital                         57,920                -
                                                -----------        ------------
  Net cash provided (used) by
    financing activities                             58,700             -
                                                ------------     ------------

  (Decrease) increase in cash                       (7,014)               932

Cash, beginning of period                             7,321                 0
                                                ------------       ----------
Cash, end of period                              $     307    $            932
                                               ============        ============

Supplemental schedule of other cash flows:

  Cash paid during the period for:

    Interest expense                         $       33,409        $     93,549
                                               ============        ============
    Income taxes                             $          800         $       800
                                               ============        ============

                              See Accompanying Notes

                              See Accompanying Notes
<page>

                        NOTES TO THE FINANCIAL STATEMENTS

I.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Nature of Business: Original Sixteen to One Mine, Inc. (the Company) was
incorporated in 1911 and is actively involved in operating gold mines in
Alleghany, California; currently, in maintenance status.

Inventory: Inventory consists of gold bullion, specimens and jewelry.  Gold
bullion and specimens are quoted at the market price for gold bullion.
Jewelry is quoted at the market price for the gold content plus labor cost.
Gold bullion is accounted for using the FIFO method.  All other inventory is
accounted for using the specific identification method.

Fixed Assets:  Fixed assets are stated at historical cost.  Depreciation is
calculated using straight-line and accelerated methods over the following
useful lives: Vehicles 3 to 5 years, Equipment 5 to 7 years, Buildings 18 to
31.5 years.

Depletion Policy:  Because of the geological formation in the Alleghany Mining
District, estimates of ore reserves currently cannot be calculated, and
accordingly, a cost per unit depletion factor cannot be determined.  Should
estimates of ore reserves become available, the units of production method of
depletion will be used.  Until such time, no depletion deduction will be
recorded.

Revenue Recognition:  As they are mined, gold specimens are recorded in
inventory and revenue is recognized using quoted market prices for gold.
For income tax purposes revenues are not recognized until the gold is sold.

Use of Estimates:  The preparation of financial statements in conformity with
generally accepted accounting principles requires management to make estimates
and assumptions.  These estimates and assumptions affect the reported amounts
of assets and liabilities at the date of the financial statements and the
reported amounts of revenues and expenses during the reporting period.  Actual
results could differ from these estimates.

  GENERAL NOTES

1.  In accordance with directive from the Securities and Exchange Commission
(SEC)and Industry Guide 7, reference for all intent and purposes to the
Company's employees as miners, its properties as mines or its operation as
mining does not diminish the fact that the Company has no proven reserves and
is in the "exploration state" as defined in Guide 7(a)(4)(iii).

2. In the opinion of management, the financial statements contain all
adjustments (consisting only of normal recurring accruals) necessary to present
fairly the Company's financial position at Sept. 30, 2010 and December 31,
2009, the results of operations for the three-month and nine-month periods
ended Sept. 30, 2010 and 2009, and the statement of cash flows for the nine-
month periods ended Sept. 30, 2010 and 2009.  The unaudited financial
statements have been prepared in accordance with Generally Accepted Accounting
Principles for interim financial information and with the instructions to Form
10-Q and Item 310(b) of Regulation S-B.

II.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF PLAN OF OPERATION

The Sixteen to One mine in the Alleghany Mining District is a unique mine and
requires a unique operation, which has been recognized by its owners, its
miners, geologists, engineers, and some public agencies during the last decade
of the twentieth century and to the present.  It is a traditional high-grade,
hard rock, underground gold mine.  The same company owns and operates
(maintains) the mine. Original Sixteen to One Mine Inc, (owner) was incorporated
in California in 1911.  Experts estimate about twenty percent of the ore
deposit has been mined.  Production is approximately 1,500,000 ounces of gold.

There are over thirty miles of horizontal workings and millions of cubic
feet of vertical excavations called stopes.  The entire grounds are not
maintained for mining.  Once an area is targeted for mining, travel ways and
escape routes are brought into safety compliance.  Production miners set up a
heading (face) and begin a drill-blast-muck sequence into the quartz.  Gold is
hosted in the quartz vein in exceedingly rich concentrations called "pockets".
Metal detectors are regularly used underground as a tool for guiding the
direction of the work.  Metal detectors are also used as a tool to separate the
ore underground.  This has the positive affect of reducing the volume of shot
rock from the mine, thereby reducing costs.

In 1992, the company initiated a gold marketing plan of selling gold in quartz
as a gemstone.  This produces revenue significantly greater than selling gold
into the spot market.  Demand for the Sixteen to One gold-in-quartz gemstone
exceeds supply.

Production has been termed a "feast or famine" situation for over 100 years.
Reserves in a high-grade gold mine cannot be termed as "proven".  The company
hoards gold and sells it according to short-term cash needs.  This fact
requires an operator to manage its cash flow to operate between pockets.  It is
difficult to undertake major expansion plans with an uncertain supply of
capital.  The Company has announced general plans to build a new shaft in the
northern section of its Alleghany patented claims.


BALANCE SHEET COMPARISONS

For the nine-month period from December 31, 2009 to Sept. 30, 2010:

Accounts receivable increased by $11,167 (301%) due to a note for refund from
an independent contractor who was paid in advance, then declined services.

Mining property decreased by $297,354 (52%) due to the sale of the Brown Bear
Mine in Trinity County (booked value $300,000) combined with an offset of
$2,646 for mining claim location fees that were capitalized.

Bonds and Miscellaneous deposits increased by $2,502 (45%) due to the posting
of a bond with State Fund Insurance Company for Worker's Compensation
Insurance.

Notes due related parties decreased by $353,608 (55%) due to the application
of an advance on the sale of the Brown Bear Mine against the purchase. See
2009 10-K notes for more information.

Notes payable due within one year decreased by $58,700 (100%) due to the
conversion of the remaining balance for the Note from Gold Country Lenders
into stock.

STATEMENT OF OPERATIONS

Revenues for the nine-month period ended Sept. 30, 2010 compared to the same
period in 2009 decreased by $32,336 (24%) due to no production and decreased
gold sales.

Operating expenses for the three-month and nine-month periods ended Sept 30,2010
increased by $118,252 (202%) and $267,213 (134%) respectively compared to the
same periods in 2009 as a result of increased maintenance activity in 2010.

Other income and expense for the three-month period ended Sept. 30, 2010
Increased on the income side by $49,224 (286%) primarily due to less interest
expense in 2010 compared to the same period in 2009.  For the nine-month period
ended Sept. 30,2010 other income (expense) increased on the income side by
$478,194 due to the sale of the Brown Bear Mine which was booked in January
combined with lower interest expenses in 2010.

For the three-month period ended Sept. 30, 2010 the company showed a loss of
$164,977 compared to a loss of $202,966 for the same period in 2009.  The
$38,019 (19%) difference is due to lower interest expenses in 2010.  For the
nine-month period ended Sept. 30, 2010 the company showed a loss of $111,406
compared to a loss of $290,051 for the same period in 2009.  The $178,645 (62%)
difference is primarily due to the sale of the Brown Bear Mine in 2010.  See
2009 - 10-K for more information.

SUBSEQUENT EVENTS

None

LIQUIDITY AND CAPITAL RESOURCES

The Company's liquidity is substantially dependent upon the results of
operations.  The Company maintains a gold inventory which it liquidates to
satisfy working capital needs.  There is no assurance that inventory is
adequate to sustain the Company.

PART II

LEGAL PROCEEDINGS

In July 2009 the Company and its president were served a complaint for damages
in Superior Court of the State of California, County of Sierra by the
California Regional Water Quality Control Board, Central Valley Region.
Discovery is ongoing.  The case number is: No. 7019.

On September 3, 2009 the Company filed a complaint against Sierra County for
damages suffered due to a gasoline and diesel leak onto its property.  Both
Sides seek settlement.  Case number 7068.

On January 6, 2010, the California Department of Conservation, formally the
Division of Mines and Geology filed a complaint for statutory reporting and
mining fees and penalties alleging failures by the Company.  Various Public
Resources Code Sections were cited substantially related to surface mining.
On March 24, 2010, the Company filed verified answers denying any wrongdoing.
Discovery is ongoing.

OTHER INFORMATION

The unaudited interim consolidated financial statements of Original Sixteen to
One Mine, Inc. (the Company) have been prepared by management in accordance
with generally accepted accounting practices.  Such rules allow the omission of
certain information and footnote disclosures normally included in financial
statements prepared in accordance with generally accepted audited accounting
principles as long as the statements are not misleading.

In the opinion of management, verified by signature below, all adjustments
necessary for a fair presentation of these interim statements have been
included.  These adjustments are of a normal recurring nature.

The preparation of the Company's financial statements in conformity with
accounting principles accepted in the United States requires management to make
estimates and assumptions.  These estimates and assumptions affect the reported
amounts of assets and liabilities and disclosure of contingent liabilities at
the date of the financial statements, as well as the reported amount of
revenues and expenses during the reporting period.  On an ongoing basis,
management evaluates its estimates and assumptions; however, actual amounts
could differ from those based on such estimates and assumptions.  No accounting
principle upon which the Company's financial status depends, requires estimates
of proven and probable reserves and/or assumptions of future gold prices.
Commodity prices may significantly affect the company's profitability and cash
flow.  No independent accounting firm or auditors have any responsibility for
the accounting and written statements of the Form 10-QSB.

The Company and its president assume responsibility for the accuracy of this
filing and certify the financial statements present fairly in all material
respects, the financial position of Original Sixteen to One Mine, Inc at Sept.
30, 2010.

CAUTIONARY STATEMENT FOR PURPOSES OF THE "SAFE HARBOR" PROVISIONS OF THE
PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995

From time to time the Original Sixteen to One Mine, Inc. (the Company), will
make written and oral forward-looking statements about matters that involve
risks and uncertainties that could cause actual results to differ materially
from projected results.  Important factors that could cause actual results to
differ materially include, among others:

- Fluctuations in the market prices of gold
- General domestic and international economic and political
  conditions
- Unexpected geological conditions or rock stability conditions
  resulting in cave-ins, flooding, rock-bursts or rock slides
- Difficulties associated with managing complex operations in remote areas
- Unanticipated milling and other processing problems
- The speculative nature of mineral exploration
- Environmental risks
- Changes in laws and government regulations, including those
  relating to taxes and the environment
- The availability and timing of receipt of necessary governmental
  permits and approval relating to operations, expansion of operations,
  and financing of operations
- Fluctuations in interest rates and other adverse financial market conditions
- Other unanticipated difficulties in obtaining necessary financing with
  specifications or expectations
- Labor relations
- Accidents
- Unusual weather or operating conditions
- Force majeure events
- Other risk factors described from time to time in the Original Sixteen to One
Mine, Inc., filings with the Securities and Exchange Commission

Many of these factors are beyond the Company's ability to control or predict.
Investors are cautioned not to place undue reliance on forward-looking
statements.  The Company disclaims any intent or obligation to update its
forward-looking statements, whether as a result of receiving new information,
the occurrence of future events or otherwise.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

ORIGINAL SIXTEEN TO ONE MINE, INC.
(Registrant)


/s/Michael M. Miller
President and Director
Dated:  November 3,2010