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                            Library & Multimedia
 A Sensitivity Analysis To Determine the Robustness of STRmix (TM) With Respect to Laboratory Calibration
NCJ Number
              253282
Journal

*Forensic Science International-Genetics* Volume: 35 Dated: July 2018 Pages: 113-122
Author(s)
          Hannah Kelly;
                        Jo-Anne Bright;
                        Maarten Kruijver;
                        Stuart Cooper;
                        Duncan Taylor;
                        Kyle Duke;
                        Melissa Strong;
                        Vickie Beamer;
                        Christina Buettner;
                        John Buckleton
Date Published

July 2018
Length
              10 pages
Annotation
              Since STRmix uses several laboratory-specific parameters to calibrate the stochastic model for peak heights, and these are modelled on empirical observations specific to the instruments and protocol used in the analysis, the current study used a sensitivity analysis to assess the extent to which these parameters can be borrowed from laboratories with similar technology and protocols without affecting the accuracy of the system.
Abstract
              Parameters were first calibrated to a publicly available dataset, after which a large number of likelihood ratios were computed for true contributors and non-contributors, using both the calibrated parameters and several borrowed parameters. Differences in the LR caused by using different sets of parameter values were found to be negligible. (publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        2017-DN-BX-0136


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)
                                Report (Study/Research)
                                Report (Grant Sponsored)
                                Program/Project Description


  
  
        
  Award
        Population Genetic Issues for Forensic DNA Profiles
    
  
  
Date Published: July 1, 2018
    
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