SECURITIES AND EXCHANGE COMMISSION
                                 WASHINGTON, D.C.  20549


                                     FORM 10-Q



                      QUARTERLY REPORT UNDER SECTION 13 OR 15(d)
                        OF THE SECURITIES EXCHANGE ACT OF 1934



   For the Quarter Ended March 31, 2010       Commission File No. 001-10156



                          ORIGINAL SIXTEEN TO ONE MINE, INC.
                (Exact name of registrant as specified in its charter)



                   CALIFORNIA                            94-0735390
      (State or other jurisdiction of     (I.R.S. Employer Identification No.)
        incorporated or organization)

                     Post Office Box 909, Alleghany, CA  95910
                      (Address of principal executive offices)


                                    (530) 287-3223
                            (Registrant's telephone number)
                                (including area code)

Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the past 12 months (or for such shorter period that the Registrant
was required to file such reports), and (2) has been subject to such filing
requirement for the past 90 days.

                        Yes:                        No:   X



As of March 31, 2010, 13,373,505 shares of Common Stock, par value $.03 per
share, were issued and outstanding.

<page>


                                   PART I

1.  FINANCIAL INFORMATION

                        Original Sixteen to One Mine, Inc.
                              Condensed Balance Sheet
                     March 31, 2010 and December 31, 2009

                                    March 31, 2010       December 31, 2009
ASSETS

Current Assets
   Cash                                  $    7,742              $   7,321
   Accounts receivable                        5,051                  3,711
   Inventory                                416,681                414,331
                                         ----------             ----------
     Total current assets                   429,474                425,363
                                         ----------             ----------

Mining Property
   Real estate and property rights
      net of depletion of $524,145          230,401                230,401
   Real estate and mineral property          47,976                345,330
                                         ----------             ----------
                                            278,377                575,731
                                         ----------             ----------
Fixed Assets at Cost
   Equipment                                925,243                925,243
   Buildings                                209,487                209,487
   Vehicles                                 255,128                255,128
                                         ----------             ----------
                                          1,389,858              1,389,858
Less accumulated depreciation            (1,308,220)            (1,303,866)
                                         ----------             ----------
     Net fixed assets                        81,638                 85,992
                                         ----------             ----------
Other Assets
   Bonds and misc. deposits                   7,962                  5,460
                                         ----------             ----------

     Total Assets                        $  797,451             $1,092,546
                                         ==========             ==========

LIABILITIES & STOCKHOLDERS' EQUITY

Current Liabilities
   Accounts payable &
      accrued expenses                      598,217                648,434
Due to related party                        217,217                647,555
Notes payable due within one year            58,700                 58,700
                                         ----------             ----------
     Total Current Liabilities              874,134              1,354,689
                                         ----------             ----------
Long Term Liabilities
   Notes payable due after one year         97,236                  97,236
                                         ----------             ----------
     Total Liabilities                      971,370              1,451,925
                                         ----------             ----------

Stockholders' Equity
   Capital stock, par value $.03:
     30,000,000 shares authorized:
     13,373,505 shares issued and
     outstanding as of March 31, 2010 and
     as of December 31, 2009                439,876                439,876
   Additional paid-in capital             2,005,282              2,005,274
   (Accumulated deficit)
      retained earnings                  (2,619,077)           (2,804,537)
                                         ----------             ----------
     Total Stockholders' Equity          (173,919)              (359,379)
                                         ----------             ----------
Total Liabilities and
  Stockholders' Equity                   $  797,451             $1,092,546
                                         ==========             ==========

                              See Accompanying Notes

<page>

                         Original Sixteen to One Mine, Inc.
                     Statement of Operations and Retained Earnings
                Three Months Ended March 31, 2009 and March 31, 2009

                             Three Months Ending March 31,
                                      2010            2009
                                    ------          ------
Revenues:
  Gold & jewelry sales             $  11,067  $     47,333
                                   -----------   -----------
     Total revenues                   11,067        47,333
                                 -----------   -----------
Operating expenses:
  Salaries and wages                  11,170        17,282
  Contract Labor                       8,792         6,765
  Telephone & utilities               11,645         8,266
  Taxes - property & payroll           10,297        9,075
  Insurance                              277           190
  Supplies                            23,441         4,571
  Small equipment & repairs            1,451         5,054
  Drayage                              7,612         1,524
  Corporate expenses                   1,150         2,775
  Compliance/safety                    1,138            73
  Legal and accounting                 2,460           245
  Depreciation & amortization          4,354         4,898
  Other expenses                      19,400         2,208
                                   ----------   ----------
  Total operating expenses           103,187        62,926
                                 ----------    ----------
  Profit (Loss) from operations     (92,120)      (15,593)

Other Income & Expenses:

Other Income                         282,071         3,258
Other Expenses                       (3691)       (26,433)
                                    -------       --------
Total Other Income (Expense)        278,380       (23,175)
                                 ----------    -----------
Profit (Loss) before taxes           186,260      (38,768)
                                 ----------    -----------
Income Tax Benefit                       800          -
Net Profit (Loss)             $      185,460   $  (38,768)
                               ============    ===========

Basic and diluted Gain
   (Loss) per share           $        .013   $     (.002)
                                 ============    ============
Shares used in the
   calculation of net
   loss income per share           13,373,505    13,373,505
                                 ============    ===========


                              See Accompanying Notes

<page>


                      Original Sixteen to One Mine, Inc.
                           Statement of Cash Flows
         Three Months Ended March 31, 2010 and March 31, 2009

                                              Three Months Ended March 31,
                                               2010                   2009
                                         --------------         --------------
Cash Flows From Operating Activities:

Net profit (loss)                       $         185,460         $  (38,768)
  operating activities:
     Depreciation and amortization                  4,354                4,898
     (Increase)Decrease in
        accounts receivable                        (1,340)                (639)
     Decrease(Increase) in inventory               (2,350)              (9,964)
     (Increase)Decrease in other
       current assets                                  -                     -
     (Decrease) increase in accounts payable
       and accrued expenses                        50,217)              309,876
    (Decrease) increase in short term notes      (430,338)            (261,383)


                                            ------------            ----------
  Net cash (used) provided by
     operating activities                        (294,431)                4,020
                                             ------------           -----------

Cash Flows From Investing Activities:

  Sale of Real Estate                              300,000              -
  Mining Claim fees, capitalized                   (2,646)              -
  (Increase) Bonds, Misc Deposits                  (2,502)              -
                                             -------------         -----------

  Net cash (used) provided by
    investing activities                           294,852              -
                                            -------------          -----------

Cash Flows From Financing Activities

  Increase (decrease) notes payable                      -                 -
  (Increase) decrease in notes receivable                -                 -
  Proceeds from sale of common stock                     -                 -
  Additional paid-in capital                             -                 -
                                               ------------        ------------
  Net cash provided (used) by
    financing activities                              -                     -
                                               ------------        ------------

  (Decrease) increase in cash                          421                4,020

Cash, beginning of period                            7,321                  -
                                                ------------         ----------
Cash, end of period                            $     7,742        $       4,020
                                               ============        ============

Supplemental schedule of other cash flows:

  Cash paid during the period for:

    Interest expense                         $       3,408         $     26,208
    Income Taxes                             $          -          $         -
    Gain on Sale of Asset                     $   280,000
                                             ============          ============

                              See Accompanying Notes
<page>

                        NOTES TO THE FINANCIAL STATEMENTS

I.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Nature of Business: Original Sixteen to One Mine, Inc. (the Company) was
incorporated in 1911 and is actively involved in operating gold mines in
Alleghany, California; currently, in maintenance status.

Inventory: Inventory consists of gold bullion, specimens and jewelry.  Gold
bullion and specimens are quoted at the market price for gold bullion.
Jewelry is quoted at the market price for the gold content plus labor cost.
Gold bullion is accounted for using the FIFO method.  All other inventory is
Accounted for using the specific identification method.

Fixed Assets:  Fixed assets are stated at historical cost.  Depreciation is
calculated using straight-line and accelerated methods over the following
useful lives: Vehicles 3 to 5 years, Equipment 5 to 7 years, Buildings 18 to
31.5 years.

Depletion Policy:  Because of the geological formation in the Alleghany Mining
District, estimates of ore reserves currently cannot be calculated, and
accordingly, a cost per unit depletion factor cannot be determined.  Should
estimates of ore reserves become available, the units of production method of
depletion will be used.  Until such time, no depletion deduction will be
recorded.

Revenue Recognition:  As they are mined, gold specimens are recorded in
inventory and revenue is recognized using quoted market prices for gold.
For income tax purposes revenues are not recognized until the gold is sold.

Use of Estimates:  The preparation of financial statements in conformity with
generally accepted accounting principles requires management to make estimates
and assumptions.  These estimates and assumptions affect the reported amounts
of assets and liabilities at the date of the financial statements and the
reported amounts of revenues and expenses during the reporting period.  Actual
results could differ from these estimates.

  GENERAL NOTES

1.  In accordance with directive from the Securities and Exchange Commission
(SEC)and Industry Guide 7, reference for all intent and purposes to the
Company's employees as miners, its properties as mines or its operation as
mining does not diminish the fact that the Company has no proven reserves and
is in the "exploration state" as defined in Guide 7(a)(4)(iii).

2. In the opinion of management, the financial statements contain all
adjustments (consisting only of normal recurring accruals) necessary to present
fairly the Company's financial position at March 31, 2010 and December 31,
2009, the results of operations and cash flows for the three-month periods
ended March 31, 2010 and 2009.  The unaudited financial statements have been
prepared in accordance with Generally Accepted Accounting Principles for
interim financial information and with the instructions to Form 10-Q and Item
310(b) of Regulation S-B.

II.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF PLAN OF OPERATION

The Sixteen to One mine in the Alleghany Mining District is a unique mine and
requires a unique operation, which has been recognized by its owners, its
miners, geologists, engineers, and some public agencies during the last decade
of the twentieth century and to the present.  It is a traditional high-grade,
hard rock, underground gold mine.  The same company owns and operates
(maintains) the mine. Original Sixteen to One Mine Inc, (owner) was incorporated
in California in 1911.  Experts estimate that less than twenty percent of the
proven and probable ore deposit has been mined.  Production is approximately
1,500,000 ounces of gold.

There are over twenty-eight miles of horizontal workings and millions of cubic
feet of vertical excavations called stopes.  The entire grounds are not
maintained for mining.  Once an area is targeted for mining, travel ways and
escape routes are brought into safety compliance.  Production miners set up a
heading (face) and begin a drill-blast-muck sequence into the quartz.  Gold is
hosted in the quartz vein in exceedingly rich concentrations called "pockets".
Metal detectors are regularly used underground as a tool for guiding the
direction of the work.  Metal detectors are also used as a tool to separate the
ore underground.  This has the positive affect of reducing the volume of shot
rock from the mine, thereby reducing costs.

In 1992, the company initiated a gold marketing plan of selling gold in quartz
as a gemstone.  This produces revenue significantly greater than selling gold
into the spot market.  Demand for the Sixteen to One gold-in-quartz gemstone
exceeds supply.

Production has been termed a "feast or famine" situation for over 100 years.
Reserves in a high-grade gold mine cannot be termed as "proven".  The company
hoards gold and sells it according to short-term cash needs.  This fact
requires an operator to manage its cash flow to operate between pockets.  It is
difficult to undertake major expansion plans with an uncertain supply of
capital.  The Company has announced general plans to build a new shaft in the
northern section of its Alleghany patented claims.


BALANCE SHEET COMPARISONS

For the three-month period ending March 31, 2010 Real estate and mineral
property decreased by $297,354 (86%) due to the sale of the Brown Bear Mine
in Trinity County.  See 2009 10-K notes for more information.

Bonds and Miscellaneous deposits increased by $2,502 (46%) due to the posting
of a bond with State Fund Insurance Company for Worker's Compensation
Insurance.

Noted due related parties decreased by $430,338 (66%) due to the application
of an advance on the sale of the Brown Bear Mine against the purchase. See
2009 10-K notes for more information.

STATEMENT OF OPERATIONS

Revenues for the three-month period ending March 31, 2010 decreased by $36,266
(77%) compared with the same period for 2009 due to lower sales of inventory
combined with no gold production.

For the three-month period ended March 31, 2010 compared to the same period in
2009 operating expenses increased overall by $30,112 (48%) due to increased
maintenance activity in 2010.

For the three-month period ended March 31, 2010 compared to the same period in
2009 other income increased by $278,813 (86%) due to the gain of $280,000 on
the sale of Brown Bear Mine.  Other expenses decreased by $22,742 (98%) due to
an adjustment to interest expense in 2009 that did not occur in 2010 as well as
less interest expense in 2010.

For the three-month period ended March 31, 2010 compared to the same period in
2009 the company showed a profit of $185,460 compared to a loss of $38,768.
The increase of $224,228 (578%) is attributable to the closing of escrow on the
sale of the Brown Bear Mine in January.  For details see the 2009 10-K notes.

LIQUIDITY AND CAPITAL RESOURCES

The Company's liquidity is substantially dependent upon the results of
operations.  The Company maintains a gold inventory which it liquidates to
satisfy working capital needs.  There is no assurance that inventory is
adequate to sustain the Company.

PART II

LEGAL PROCEEDINGS

In July 2009 the Company and its president were served a complaint for damages
in Superior Court of the State of California, County of Sierra by the
California Regional Water Quality Control Board, Central Valley Region.
Discovery is ongoing.  The case number is: No. 7019.

On January 6, 2010, the California Department of Conservation, formally the
Division of Mines and Geology filed a complaint for statutory reporting and
mining fees and penalties alleging failures by the Company.  Various Public
Resources Code Sections were cited substantially related to surface mining.
On March 24, 2010, the Company filed verified answers denying any wrongdoing.
Discovery is ongoing.

On September 3, 2009 the Company filed a complaint against Sierra County for
damages suffered due to a gasoline and diesel leak onto its property.  Both
Sides seek settlement.  Case number 7068.

SUBSEQUENT EVENTS

none

OTHER INFORMATION

The unaudited interim consolidated financial statements of Original Sixteen to
One Mine, Inc. (the Company) have been prepared by management in accordance
with generally accepted accounting practices.  Such rules allow the omission of
certain information and footnote disclosures normally included in financial
statements prepared in accordance with generally accepted audited accounting
principles as long as the statements are not misleading.

In the opinion of management, verified by signature below, all adjustments
necessary for a fair presentation of these interim statements have been
included.  These adjustments are of a normal recurring nature.

The preparation of the Company's financial statements in conformity with
accounting principles accepted in the United States requires management to make
estimates and assumptions.  These estimates and assumptions affect the reported
amounts of assets and liabilities and disclosure of contingent liabilities at
the date of the financial statements, as well as the reported amount of
revenues and expenses during the reporting period.  On an ongoing basis,
management evaluates its estimates and assumptions; however, actual amounts
could differ from those based on such estimates and assumptions.  No accounting
principle upon which the Company's financial status depends, requires estimates
of proven and probable reserves and/or assumptions of future gold prices.
Commodity prices may significantly affect the company's profitability and cash
flow.  No independent accounting firm or auditors have any responsibility for
the accounting and written statements of the Form 10-QSB.

The Company and its president assume responsibility for the accuracy of this
filing and certify the financial statements present fairly in all material
respects, the financial position of Original Sixteen to One Mine, Inc at March
31, 2009.

CAUTIONARY STATEMENT FOR PURPOSES OF THE "SAFE HARBOR" PROVISIONS OF THE
PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995

From time to time the Original Sixteen to One Mine, Inc.  (the Company), will
make written and oral forward-looking statements about matters that involve
risks and uncertainties that could cause actual results to differ materially
from projected results.  Important factors that could cause actual results to
differ materially include, among others:

- Fluctuations in the market prices of gold
- General domestic and international economic and political
  conditions
- Unexpected geological conditions or rock stability conditions
  resulting in cave-ins, flooding, rock-bursts or rock slides
- Difficulties associated with managing complex operations in remote areas
- Unanticipated milling and other processing problems
- The speculative nature of mineral exploration
- Environmental risks
- Changes in laws and government regulations, including those
  relating to taxes and the environment
- The availability and timing of receipt of necessary governmental
  permits and approval relating to operations, expansion of operations,
  and financing of operations
- Fluctuations in interest rates and other adverse financial market conditions
- Other unanticipated difficulties in obtaining necessary financing with
  specifications or expectations
- Labor relations
- Accidents
- Unusual weather or operating conditions
- Force majeure events
- Other risk factors described from time to time in the Original Sixteen to One
Mine, Inc., filings with the Securities and Exchange Commission

Many of these factors are beyond the Company's ability to control or predict.
Investors are cautioned not to place undue reliance on forward-looking
statements.  The Company disclaims any intent or obligation to update its
forward-looking statements, whether as a result of receiving new information,
the occurrence of future events or otherwise.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the
Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

ORIGINAL SIXTEEN TO ONE MINE, INC.
(Registrant)


/s/Michael M. Miller
President and Director
Dated:  June 15, 2010