<TABLE> <S> <C>

<PAGE>
 
<ARTICLE> 9
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM CONSOLIDATED
FINANCIAL STATEMENTS AND NOTES THERETO OF FIRST MISSOURI BANCSHARES, INC. AT AND
FOR THE YEAR ENDED SEPTEMBER 30, 1996 AND IS QUALIFIED IN ITS ENTIRETY BY
REFERENCE TO SUCH FINANCIAL STATEMENTS.  DOLLAR AMOUNTS (OTHER THAN PER SHARE
DATA) IS IN THOUSANDS.
</LEGEND>
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   12-MOS
<FISCAL-YEAR-END>                          SEP-30-1996
<PERIOD-END>                               SEP-30-1996
<CASH>                                           1,326
<INT-BEARING-DEPOSITS>                             194
<FED-FUNDS-SOLD>                                     0
<TRADING-ASSETS>                                     0
<INVESTMENTS-HELD-FOR-SALE>                      7,171
<INVESTMENTS-CARRYING>                             264
<INVESTMENTS-MARKET>                               264
<LOANS>                                         36,436
<ALLOWANCE>                                        370
<TOTAL-ASSETS>                                  47,068
<DEPOSITS>                                      38,024
<SHORT-TERM>                                     3,000
<LIABILITIES-OTHER>                                319
<LONG-TERM>                                          0
<PREFERRED-MANDATORY>                                0
<PREFERRED>                                          0
<COMMON>                                             3
<OTHER-SE>                                       5,362
<TOTAL-LIABILITIES-AND-EQUITY>                  47,068
<INTEREST-LOAN>                                  3,250
<INTEREST-INVEST>                                  521
<INTEREST-OTHER>                                    32
<INTEREST-TOTAL>                                 3,803
<INTEREST-DEPOSIT>                               1,948
<INTEREST-EXPENSE>                               2,034
<INTEREST-INCOME-NET>                            1,769
<LOAN-LOSSES>                                      137
<SECURITIES-GAINS>                                   4
<EXPENSE-OTHER>                                  1,303
<INCOME-PRETAX>                                    476
<INCOME-PRE-EXTRAORDINARY>                         476
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                       293
<EPS-PRIMARY>                                     1.08
<EPS-DILUTED>                                     1.08
<YIELD-ACTUAL>                                    4.09
<LOANS-NON>                                        493
<LOANS-PAST>                                       512
<LOANS-TROUBLED>                                     0
<LOANS-PROBLEM>                                  1,700
<ALLOWANCE-OPEN>                                   301
<CHARGE-OFFS>                                       70
<RECOVERIES>                                         2
<ALLOWANCE-CLOSE>                                  370
<ALLOWANCE-DOMESTIC>                               370
<ALLOWANCE-FOREIGN>                                  0
<ALLOWANCE-UNALLOCATED>                              0
        

</TABLE>