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                            Library & Multimedia
 Novel Technique Improves Analysis of Thermally Unstable Illicit Drugs
NCJ Number
              254768

Date Published

June 2020
Length
              1 page
Annotation
              This National Institute of Justice-funded study sought to improve the analysis of illicit drugs, such as methamphetamine, when heated in gas chromatographs.
Abstract
              Analyzing illicit drugs such as methamphetamine can be complicated because the drugs break down when heated in gas chromatographs. National Institute of Justice-funded scientists from Purdue University sought to improve the analysis of thermally unstable drugs through a combination of derivatization and a novel total vaporization solid phase microextraction (TV-SPME) technique. The researchers, led by chemist John Goodpaster, analyzed 33 drugs and drug variants to compare standard liquid injections to the novel TV-SPME method. They found that drugs such as amphetamine, 2C-I (a psychedelic), and lorazepam could be identified with TV-SPME directly; however, other drugs could not, requiring an additional derivatization step. The derivatization was done using a modification of the solid phase microextraction in which chemical compounds were collected on a special fiber and then vaporized.
      
  
          Additional Details
Grant Number(s)
        2015-DN-BX-K058


  
  
        
  Agencies
        NIJ


  
  
        
  Publication Type
        Research (Applied/Empirical)
                                Report (Study/Research)
                                Report (Grant Sponsored)
                                Program/Project Description


  
  
        
  Award
        Automated Derivatization and Identification of Controlled Substances via Total Vaporization Solid Phase Microextraction (TV-SPME) and Gas Chromatography/Mass Spectrometry (GC/MS)
    
  
  
Date Published: June 1, 2020
    
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