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                            Library & Multimedia
 Microbiota succession throughout life from the cradle to the grave
NCJ Number
              305222

Author(s)
          C. Martino;
                        A. H.  Dilmore;
                        Z. M. Burcham;
                        J. L. Metcalf;
                        D. Jeste;
                        R. Knight
Date Published

2022
Annotation
              In this Review, we explore microbial succession in the healthy human microbiota from the cradle to the grave.
Abstract
              We discuss the stages from primary succession at birth, to disruptions by disease or antibiotic use, to microbial expansion at death. We address how these successions differ by body site and by domain (bacteria, fungi or viruses). We also review experimental tools that microbiota researchers use to conduct this work. Finally, we discuss future directions for studying the microbiota’s relationship with age, including designing consistent, well-powered, longitudinal studies, performing robust statistical analyses and improving characterization of non-bacterial microorganisms. (Publisher abstract provided)
      
  
          Additional Details
Grant Number(s)
        2016-DN-BX-4194
                                2016-DN-BX-0194


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)


  
  
        
  Award
        Improving Estimates of the Postmortem Interval with Metagenomics and Metabolomics
                                Habitat Specialization and the Evolution of Dispersal
    
  
  
Date Published: January 1, 2022
    
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