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                            Library & Multimedia
 Population-Specific F-ST Values for Forensic STR Markers: A Worldwide Survey
NCJ Number
              251282
Journal

*Forensic Science International-Genetics* Volume: 23 Dated: July 2016 Pages: 91-100
Author(s)
          J.  Buckleton;
                        J.  Curran;
                        J.  Goudet;
                        D.  Taylor;
                        A.  Thiery;
                        B. S. Weir
Date Published

July 2016
Length
              10 pages
Annotation
              This article reports on a project that shows FST (population structure quantity) can be estimated from sample allelic matching proportions within and between populations.
Abstract
              The interpretation of matching between DNA profiles of a person of interest and an item of evidence is undertaken using population genetic models to predict the probability of matching by chance. Calculation of matching probabilities is straightforward if allelic probabilities are known, or can be estimated, in the relevant population. It is more often the case, however, that the relevant population has not been sampled and allele frequencies are available only from a broader collection of populations as might be represented in a national or regional database. Variation of allele probabilities among the relevant populations is quantified by the population structure quantity FST and this quantity affects matching proportions. Matching within a population can be interpreted only with respect to matching between populations. The current project reports that estimates from sample allelic matching proportions within and between populations were obtained from data in 250 papers in the forensic literature, representing STR profiles at up to 24 loci from nearly 500,000 people in 446 different populations. The results suggest that theta values in current forensic use do not have the buffer of conservatism often thought. (Publisher abstract modified)
      
  
          Additional Details
Grant Number(s)
        2011-DN-BX-K541
                                2014-DN-BX-K028


  
  
        
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        NIJ-Sponsored


  
  
        
  Publication Type
        Survey
                                Research (Applied/Empirical)
                                Report (Study/Research)
                                Report (Grant Sponsored)
                                Program/Project Description


  
  
        
  Award
        Population Genetic Issues for Forensic DNA Profiles
                                Population Genetic Issues for Forensic DNA Profiles
    
  
  
Date Published: July 1, 2016
    
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