U.S. flag
      An official website of the United States government, Department of Justice.
        Here's how you know
      Here's how you know**Official websites use .gov**
            
            A **.gov** website belongs to an official government organization in the United States.
      **Secure .gov websites use HTTPS**
            
            A **lock** (
            A locked padlock
            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites. Menu

      
        close

            
            
                                              About NIJ
        
                    
  
          About NIJ
      
    
          The NIJ Director
          How NIJ Is Organized
          Mission and Guiding Principles
          Research and Development Process
          Strategic Framework
          Assessments of NIJ
          Annual Reports & Reports to Congress
          Staff Directory
          Funding & Awards
        
                    
  
          Funding & Awards
      
    
          Current Funding
          Forthcoming Funding
          Expired Funding
          Awards: Listing of Funded Projects
          Guidance for Applicants and Awardees
          Fellowship & Student Programs
          Travel Scholarships
          NIJ Challenge Program
          Library & Multimedia
        
                    
  
          Library & Multimedia
      
    
          NIJ Journal
          Podcasts
          Publications Listing
          Multimedia Listing
          Rated Practices on CrimeSolutions
          Rated Programs on CrimeSolutions
          Software & Databases
          Datasets
          Patents
          Topics
        
                    
  
          Topics
      
    
          Article Listing
          Corrections
          Courts
          Crime Prevention
          Crimes
          Drugs and Crime
          Equipment and Technology
          Forensic Sciences
          Youth Justice
          Justice System Reform
          Law Enforcement
          Tribal Crime and Justice
          Victims of Crime
          Events
        
                    
  
          Events
      
    
          NIJ 2024 Research Conference
          Scheduled Events
          On-Demand Events
          Research Meetings & Workshops
          NIJ-Hosted Online Training

                            
                                About
          Contact Us
          Subscribe
          Topics A-Z
                  Share
FacebookXLinkedInRedditPinterestEmail Home
                            Library & Multimedia
 Part I. Synthetic Investigations of Heterocyclic Natural and Unnatural Compounds: Part II. New Approach to Latent Fingerprint Detection on Paper
NCJ Number
              248496

Author(s)
          Jisun Lee Ph.D.
Date Published

July 2014
Length
              84 pages
Annotation
              This study researches various natural compounds developed over the years as chemical agents for fingerprint detection, and presents a new approach to provide an alternative method of fingerprint detection that could be utilized in challenging situations.
Abstract
              The didemnin family of marine depsipeptides, as well as the closely related tamandarin family, have been of great interest to the scientific community since their discovery in 1981. This five chapter dissertation presents and discusses depsipeptides and their therapeutic and practical uses, notably their use in latent fingerprint detection. Chapter 1 discusses the biological and synthetic significance of the didemnins, tamandarins, and related natural products. Chapter 2 presents improved second-generation synthesis of the tamandarin B macrocycle and its successful application to the syntheses of three novel tamandarin B analogues. The results of these investigations help explain the structure-activity relationship, as well as mode of action, of these natural products. Chapter 3 deals with the generation of structurally intriguing azabicyclic and aminocyclopropanes, and their application in ring-opening conditions beneficial to pharmaceutical motifs. Chapter 4 introduces a rapidly growing family of natural diketopiperazine alkaloids: epipolythiodiketopiperazine (ETP) alkaloids, and related synthetic efforts in the generation of these alkaloids. Extensive synthetic investigation towards the formal synthesis of epicoccin G and other related alkaloids have been conducted. A novel methodology to access the framework present in many ETP alkaloids is discussed. Chapter 5 deals with the development and successful application of 1,2-indanedione functionalized gold nanoparticles in a modified multi-metal deposition process for the development of latent fingerprints on paper. Although a wide variety of ninhydrin-like compounds have been developed as chemical agents for this process over the years, considerable portions of latent fingerprints still escape detection. The new approach provides an alternative method of fingerprint detection that could be utilized in challenging situations.
      
  
          Additional Details
Grant Number(s)
        2012-IJ-CX-0019


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Report (Grant Sponsored)


  
  
        
  Award
        Development of Novel 1,2-Indanedione Fingerprint Reagents
    
  
  
Date Published: July 1, 2014
    
          Downloads
        
                      PDF

Side navigation
  

        

  
  
              NIJ Journal
    
      
            
            
            
      Podcasts
    
      
            
            
            
      Publications Listing
    
      
            
            
            
      Multimedia Listing
    
      
            
            
            
      Rated Practices on CrimeSolutions
    
      
            
            
            
      Rated Programs on CrimeSolutions
    
      
            
            
            
      Software & Databases
    
      
            
            
            
      Datasets
    
      
            
            
            
      PatentsRelated Topics
        
                Fingerprint analysis
        Fingerprint detection techniques
        Fingerprints
        Forensic sciences
        Justice system



  
Similar Publications
        
                      NamUs Fiscal Year 2022 Annual Report
                  Technical Note – Direct Analysis In Real Time Mass Spectrometry (DART-MS)
                  A liquid chromatography electrospray ionization tandem mass spectrometry method for quantification of up to eighteen cannabinoids in hemp-derived products
 Top

      National Institute of Justice

        
        
                        About NIJ
                    About NIJ
      
    
                  How NIJ Is Organized
      
    
                  NIJ Director
      
    
                  Research Disclaimer
      
    
                  Funding & Awards
                    Funding & Awards Home
      
    
                  Awards Listing
      
    
                  Current Funding
      
    
                  Guidance for Applicants and Awardees
      
    
                  Resources
                    Events
      
    
                  Podcasts
      
    
                  Publications
      
    
                  Topics
      
    
                  Multimedia
      
    
                  Reuse Policy
      
    
                  Contacts
                    Contact NIJ
      
    
                  Staff Directory
      
    
                  Submit a FOIA Request
      
    
                  File a Civil Rights ComplaintFacebook
          
                      X
          
                      YouTube
  

      810 7th St. NW, Washington, D.C. 20531
      
              Secondary Footer link menu
            Accessibility
              Plain Language
              Privacy Policy
              Legal Policies and Disclaimer
              No FEAR Act
              Freedom of Information Act
              USA.gov
              Justice.gov