EX-10.5



 Exhibit 10.5 

EMPLOYMENT AGREEMENT 

by and between CONTRAFECT 

CORPORATION and 
 DAVID
HUANG, M.D. 
 THIS EMPLOYMENT AGREEMENT (the “Agreement”) is entered into on the latest date set forth on the signature pages
hereto, by and between ContraFect Corporation, a Delaware corporation (“Employer”) and David Huang, M.D., a resident of New York City (“Employee”). 

WHEREAS, Employer is a biotech company engaged in the business of developing products for approval and sale; 

WHEREAS, Employee is a research scientist with knowledge and experience in the area of developing products in the biotech field for approval
and sale; 
 WHEREAS, Employer believes that the future services of Employee will be of substantial benefit to Employer and desires to
assure itself of the continued availability of such services; and 
 WHEREAS, Employee desires to accept employment with Employer on the
terms and subject to the conditions hereinafter stated. 
 NOW, THEREFORE, for and in consideration of the premises above and the mutual
promises contained herein and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 

1. Employment and Duties of Employee. 
 (a)
Employer hereby employs Employee to serve Employer in the capacity of Chief Medical Officer reporting to Employer’s Chief Executive Officer Employer shall have the power to determine the precise duties of Employee as they may change over time
and as Employer’s needs shall warrant. Employee agrees to devote Employee’s full working time, attention, ability, skill and energies to the performance of 







 
Employee’s duties hereunder. Employee shall provide professional services on behalf of Employer in a manner and to an extent consistent with that established by Employer. Employee shall work
at all locations/offices of Employer as requested by Employer, and upon Employer’s request shall travel as needed to carry out his duties. Employee shall not provide like services for any other entity or person, whether for compensation or not,
except as an employee of Employer. 
 (b) Employee shall comply with all bylaws, policies, procedures, standards and regulations of Employer
now or hereafter promulgated. Employee shall participate in such continuing education as may be required under applicable ethical or licensing standards, laws, rules and regulations applying to Employee’s profession or as may otherwise be
required by Employer. Employee shall obtain and maintain all required licenses, credentials, approvals or other certifications to perform Employee’s duties and services hereunder. 

(c) Employee shall disclose in writing to Employer on the date hereof all financial interests or compensation arrangements of Employee (other
than this Employment Agreement) in any Biotech Venture (Biotech Venture shall mean and include without limitation, any entity or person that develops or sells, researches, or licenses scientific information or products for the therapy of human
diseases)(such financial interests and compensation arrangements hereinafter collectively referred to as “Arrangements”). 

Employee shall not enter into any Arrangements with any Biotech Venture without the prior written consent of Employer. 

2. Hours and Place of Employment. Employee is expected to maintain a regular work week as assigned by the Employer for employees at his level
performing such duties. Employee shall be assigned to work at Employer’s headquarters location in Yonkers, New York. 
 3. Term of Employment.
The initial term of employment (the “Initial Term”) of Employee’s employment by Employer under this Agreement shall commence on September 1, 2011 (the “Commencement Date”) and shall end four (4) years thereafter,
unless earlier terminated as hereinafter provided. Unless either party elects to terminate this Agreement at the end of the Initial Term or any renewal term by giving the other party notice of such election at least ninety (90) days before the
expiration of the Initial Term, this Agreement shall be deemed to have been renewed for an additional term of one (1) year commencing on the day after the expiration of the then current term and so on from year to year. Notwithstanding the
foregoing, either party shall have the right to terminate this Agreement at any time for any reason or no reason upon thirty (30) days’ 

  
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prior written notice. In the event that Employer or Employee gives notice to terminate pursuant to the foregoing sentence, Employer may elect to have Employee cease working immediately so long as
Employer continues to pay Employee his base salary in accordance with the provisions of Section (4)(a) hereof for the entire thirty (30) day notice period. In the event Employer elects to have Employee immediately cease working during the
thirty (30) days notice period as provided in the foregoing sentence and Employee finds alternative employment that is not in violation of any provision herein, Employee may accept and engage in the alternative employment and upon
Employee’s first date of employment with the alternative employer, Employer shall terminate the payment of Employee’s base salary during the thirty (30) day notice period as provided in subsection 4(a). In the event that Employee is
terminated by Employer without cause then in such event Employee shall be given a severance payment in the amount that is equal to twelve (12) months of his then base salary provided that Employee first signs a Severance and Release Agreement
in a form prescribed by Employer. The aforesaid severance payment shall be paid over twelve (12) months and shall be subject to mitigation by Employee. 

4. Compensation of Employee. 
 (a) As
compensation for all services to be performed by Employee from and after the Commencement Date, Employer agrees to pay to Employee a base salary of Three Hundred Fifty Thousand Dollars ($350,000.00) per annum. All such payments shall be prorated for
any partial month or year and shall be payable in accordance with Employer’s customary payroll practices for Employees. Federal income taxes, social security taxes and other customary employee payroll deductions shall be deducted from all
amounts paid to Employee as compensation under this Employment Agreement. Employer will review Employee’s performance annually at which time Employee’s base salary may subsequently be changed. 

(b) Effective as of the Commencement Date Employer shall give Employee stock options for Two Hundred Thousand (200,000) shares of common
stock under its stock option plan which will provide, among other things, for vesting in annual increments, at a $1.29 per share strike price, over three years (66,666 shares at the end of the first year, 66,666 shares at the end of the second year,
and 66,668 shares at the end of the third year. Such options shall have a duration of 10 years. The stock option plan provides, inter alia, that unvested options shall be forfeited in the event that Employee is no longer an employee as of the
vesting date. 
 (c) The Employee will also qualify for an annual bonus based on the criteria to be determined by Employer in the first
thirty (30) days of each employment year. The bonus shall be in the amount of 25% of the then base salary and shall be paid 

  
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50% in cash and 50% as options derived from Employer’s stock option plan. Such options shall have a duration of 10 years and vest over a period of 3 years as described in 4(b) with an
exercise price at the fair market value on the date of approval by the Board of Directors. Employer shall review Employee’s performance annually with a view towards setting criteria for possible additional bonus arrangements. 

(d) Employee shall be entitled to participate in such fringe benefit programs as Employer may offer to its senior employees generally. The
Employer’s current health insurance plan is with Empire Blue Cross/Blue Shield and also includes optical and dental coverage. Employer reserves the right, subject to decisions of its Board of Directors, to amend, decrease or discontinue any
benefit program at any time without advance notice to or consent of the Employee, consistent with the manner in which Employer changes the benefit programs for other similarly situated employees of Employer. 

(e) Within thirty (30) days of commencing employment Employer will give Employee a signing bonus in the form of fully vested stock
options for Fifty Eight Thousand One Hundred Forty (58,140) shares of common stock under its stock option plan which will provide, among other things, for the options to be forfeited in the event that Employee should voluntarily terminate his
employment with Employer within the first year of his employment. Such options shall have a duration of 10 years and shall have the same criteria as that listed in Section 4(b). The stock option plan provides, inter alia, that unvested
options shall be forfeited in the event that Employee is no longer an employee as of the vesting date. 
 (f) Within thirty (30) days
of commencing employment Employer will give Pace Law School an educational stipend of Ten Thousand ($10,000.00) Dollars for Employee to use in pursuit of educational endeavors. 

5. Absences and Vacation. In each calendar year of Employee’s employment Employee shall have off as paid vacation the Christmas/New Years break
starting with December 23 as the first day off and ending on January 1 of the following year. In addition, in each calendar year of Employee’s employment Employee shall be entitled to take fourteen (14) days off as paid vacation
during the summer. Employee shall be entitled to five (5) paid sick days and two personal days in each year of Employee’s employment. Except as to sick days, vacation time off shall be taken at a time reasonably convenient to Employer. In
the event Employee’s employment terminates prior to the end of the term hereof, such entitlement shall be prorated. Any unused time off at the end of any annual term of this Agreement shall not entitle Employee to payment therefor and may not
be carried forward into any subsequent period of employment. All vacation and sick time shall be prorated if Employee’s employment shall start or end during a calendar year. 

  
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 6. Expenses. 
 (a)
In addition to the compensation payable to Employee under Section 4, Employer agrees to reimburse Employee for approved expenses reasonably incurred during the course of Employee’s employment. Such reimbursement shall be made upon
presentation of receipts satisfactory to Employer for expenses actually incurred in connection with the foregoing. 
 7. Termination Other Than For
Cause. 
 (a) In the event of Employee’s death, Employee’s employment shall terminate immediately and Employee’s estate
shall be paid Employee’s base salary and accrued bonus, if any, through the date on which such death occurred. 
 (b) If Employee after
working for six (6) months for Employer becomes unable to perform the essential functions of Employee’s duties (with reasonable accommodation, if requested) due to partial or total disability or incapacity resulting from a mental or
physical illness or injury or any similar cause, Employer will continue the payment of Employee’s base salary pursuant to Section 4(a) for a period of three (3) months, or until the Employee is able to return to work, whichever is
shorter. The first days of said salary continuation shall be charged against any of Employee’s accrued and unused vacation time, sick time and personal days. Thereafter, Employer shall have no obligation for the payment of Employee’s base
salary pursuant to Section 4(a) to Employee during the continuance of such disability or incapacity. Any disability payments that are paid to Employee from Employer provided disability insurance shall be applied as an offset against
Employer’s salary continuation under this subsection 7(b). Notwithstanding anything to the contrary contained herein, Employee shall not be entitled to receive base salary pursuant to this subsection 7(b) for more than three (3) months in any
consecutive twelve (12) month period. At such time as the Family and Medical Leave Act shall apply to Employer, if ever, Employee shall have such rights as are provided for thereunder. 

8. Termination For Cause. 
 (a) Employee’s
employment under this Agreement shall be deemed to be terminated upon the occurrence of any of the following, at Employer’s election, immediately upon Employer giving written notice of such termination to Employee: 

(i) Employee’s conviction of any felony or a crime involving moral turpitude. 

  
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 (ii) Employee’s failure or refusal to follow, in any material respect, the instructions of
Employer or the bylaws, policies, standards or regulations of Employer, which from time to time may be established or changed, and such failure or refusal is not cured within fifteen (15) days of receiving written notice of such violation from
Employer. 
 (iii) Employee’s continued failure or refusal to faithfully and diligently perform, in any material respect, the usual
and customary duties of Employee’s employment hereunder, and such failure or refusal is not cured within fifteen (15) days of receiving written notice of such violation from Employer. 

(iv) Employee’s conduct is unprofessional, unethical, immoral or fraudulent and such conduct is not cured within fifteen (15) days
of receiving written notice to cure such conduct from Employer. 
 (v) Employee’s conduct is detrimental to the reputation, character
or standing of Employer. 
 (vi) Unlawful use by Employee of narcotics or other controlled substances, or use of alcohol or other drugs in
a manner Employer reasonably determines interferes with the performance of the essential functions of Employee’s duties hereunder. 

(vii) Employee’s failure or refusal to behave in a reasonably courteous, respectful and helpful manner toward third parties or
co-workers and such behavior is not cured within ten (10) days of receiving notice to cure such behavior from Employer. 
 (viii) Any
written notice under this Section 9(a) shall specify the alleged violations in sufficient detail as to apprise Employee of the default or failure. 

(b) In the event that Employer fails to pay Employee any installment of the base salary owed to Employee under Section 4(a) or
(b) when it is due and such non-payment is not cured within fifteen (15) days after Employee shall have notified Employer in writing of such non-payment, then Employee, provided that. Employee is not in default with respect to any of
Employee’s obligations under this Agreement, shall have the option to terminate Employee’s employment under this Agreement immediately upon Employee giving written notice of such termination to Employer. 

  
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 9. Proprietary and Confidential Information. 

a. Confidential Information. Employee acknowledges that, during the course of his service with Employer, he will have access to Confidential
Information and materials not generally known outside Employer. For all purposes of this Agreement, “Confidential Information” means all information and materials (whether conceived or developed by Employee or others), marketing and other
business plans, customers and customer information, data strategies, research, reports, copyrights and patents related to Employer. During the Term of this Agreement, Employee shall not, without the prior consent of Employer, communicate or divulge
any Confidential Information or materials to anyone other than Employer and its partners, affiliates, employees, consultants and those designated by it except in the course of carrying out his duties or as required by law. Employee acknowledges that
Confidential Information is and shall remain the property of Employer. The confidentiality obligations hereunder shall not apply to Confidential Information which: (i) is, or later becomes, public knowledge other than by breach of this
Agreement; or (ii) is in the possession of Employee with the full right to disclose same prior to his receipt of it from Employer; or (iii) is independently received by Employee from a third party, with no restrictions of disclosure.
Furthermore, Employee agrees not to use Confidential Information for any purposes other than to perform duties for Employer hereunder. Employee shall also execute Employer’s standard Confidentiality Agreement. 

b. Ownership of Patents and Intellectual Property. Employee agrees that any work prepared for Employer from the date of this Agreement until
the expiration of his employment with Employer, which is eligible for copyright and patent protection under the laws of the United States or any other country and any proprietary know-how developed by Employee while rendering services for Employer,
will vest in Employer. Employee hereby grants, transfers and assigns all right, title and interest in such work and all copyrights and patents in such work and all renewals and extensions thereof to Employer, and agrees to provide all assistance
reasonably requested by Employer in the establishment, preservation and enforcement of Employer’s copyright and patents in such work, such assistance to be provided at Employer’s expense but without any additional compensation to Employee
if Employee is employed by Employer and for reasonable compensation and subject to his reasonable availability if he is not. If Employer cannot, after reasonable effort, secure Employee’s signature on any documents needed do apply for or
prosecute any patent, copyright or other right or protection relating to an invention, whether because of his physical or mental incapacity or for any other reason whatsoever, Employee hereby irrevocably designates and appoints Employer and its duly
authorized officers and agents as his agent and attorney-in-fact, to act for and on his behalf and in his name and stead for the purpose of executing and filing any such application or 

  
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applications and taking all other lawfully permitted actions to further the prosecution and issuance of patents, copyrights, or similar protections thereon, with the same legal force and effect
as if executed by him. 
 c. Litigation. Employee agrees to render assistance and cooperation to Employer at its request regarding any
matter, dispute or controversy with which Employer may become involved and of which Employee has useful knowledge, information or expertise. Such services will be without additional compensation if Employee is then employed by Employer and for
reasonable compensation and subject to his reasonable availability if he is not. Following his employment, Employee shall not be required to cooperate other than as a fact witness. Employer agrees to pay all expenses reasonably incurred or to be
incurred by Employee in connection with his cooperation. 
 10. Covenants not to Compete. 

a. Non-competition. Employee acknowledges that his duties hereunder and the services he will provide to Employer are of a special, unique,
unusual and extraordinary character, which gives this Agreement particular value to Employer, and that the knowledge he will learn while working for Employer is such that it will necessarily be valuable to a competitor and almost impossible to keep
confidential if Employee were to work for a competitor. Therefore, during the Term and for a period of one year after termination of his service to Employer, Employee will not, directly or indirectly, enter into, organize, control, engage in, be
employed by, serve as a consultant to, be an officer or director of, or have any direct investment of more than 5% of the outstanding shares in, any business, person, partnership, association, firm, corporation, or other entity engaged in any
business activity (including, but not limited to, research, development, manufacturing, selling, leasing, licensing or providing services; excluding, but not limited to, clinical patient care) which is competitive with the business of Employer. For
purposes of this Agreement, a business activity is competitive with the business of the Company if it is being done on behalf of, any business, person, partnership, association, firm, corporation, or other entity that owns, develops, sells,
researches, or licenses scientific information, or products involving antibodies, lysins and other bacterial products, but does not include any other anti-microbial agents for the treatment of human pathogens. 

b. Non-diversion. During the Term, and for a period of one year after the date of termination of Employee’s employment with Employer,
Employee will not divert or attempt to divert or take advantage of or attempt to take advantage of any actual or potential business or opportunities of Employer. 

  
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 c. Non-recruitment. Employee agrees that Employer has or will invest substantial time and effort
in assembling its workforce. Accordingly, Employee agrees that during the Term and for a period of one year after the date of termination of Employee’s employment with Employer Employee will not directly or indirectly (a) hire away any
individuals who were employed by, or providing independent contractor services to, Employer during the one-year period prior to the date of termination of Employee’s service with Employer, or (b) directly or indirectly, entice, solicit or
seek to induce or influence any such employees, or independent contractors, to leave or curtail their service with Employer or to provide services to others. In addition, Employee agrees that for a period of one year after the date of termination of
Employee’s employment with Employer Employee will not directly or indirectly solicit any customer of Employer for the benefit of Employee or any other business venture 

11. Remedies. 
 a. Employee acknowledges that
the restrictions contained in Sections 9 and 10, in view of the nature of the business of Employer, are reasonable and necessary in order to protect the legitimate interests of Employer. Employee acknowledges that any violation of such restrictions
would likely result in irreparable injuries to Employer, and Employee therefore acknowledges that, in the event of Employee’s violation of any of these restrictions, Employer shall be entitled to seek from any court of competent jurisdiction
preliminary and permanent injunctive relief without proving actual damage or immediate or irreparable harm and without posting any bond. In addition, Employer shall be entitled to seek damages and an equitable accounting of all earnings, profits and
other benefits arising from such violation, which rights shall be cumulative and in addition to any other rights or remedies to which Employer may be entitled. 

b. If the time, geographic, or other limitations specified in Sections 9 and 10 above should be adjudged to exceed limitations permitted by
applicable law in any proceeding, then the affected provisions shall be deemed reformed in such jurisdiction to the maximum time, geographic, product or service or other limitations permitted by applicable law. If Employee violates any of the
restrictions contained in the foregoing Sections 9 and 10, the restrictive period shall be tolled, and shall not run, during the time of any said breach. 

c. In view of the difficulty of determining the amount of damages that may result to the parties hereto from the breach of the provision of
Section 9 or 10, it is the intent of the parties hereto that, in addition to monetary damages, any non-breaching party shall have the right to prevent any such breach in equity or otherwise, including without limitation prevention by means of
injunctive relief. The prevailing party in any such action shall be entitled to an award of its reasonable attorney’s fees and costs. 

  
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 12. Non-disparagement. Employee and Employer mutually agree that, during the Term and for a period of five years
thereafter, neither will directly or indirectly disparage the other. 
 13. Entire Agreement; Amendments. This Agreement constitutes the entire agreement
and understanding between Employer and Employee relating to the subject matter hereof, and shall not be amended or changed except by written instrument signed by each of the undersigned parties. There are no prior or contemporaneous oral or written
understandings or agreements between the parties regarding Employee’s employment by Employer or any other matter. 
 14. No Waiver. Neither
Employee nor Employer shall by any act, delay, indulgence, omission or otherwise be deemed to have waived any right or remedy hereunder or to have acquiesced in any default in or breach of any of the terms and conditions hereof. No failure to
exercise, nor any delay in exercising, on the part of Employee or Employer, any right, power or privilege hereunder shall operate as a waiver thereof. No single or partial exercise of any right, power or privilege hereunder shall preclude any other
or further exercise thereof or the exercise of any other right, power or privilege. 
 15. Waiver of jury trial. The parties hereto waive any and all rights
to a trial by jury with respect to any action arising hereunder. 
 16. Governing Law, Venue, Interpretation of Language. The parties agree that this
Agreement shall be governed by the laws of the State of New York and that venue for an action between the parties that arises out of this Agreement shall be in New York county, State of New York. In the event an ambiguity or question of intent or
interpretation arises, this Agreement shall be construed as if drafted jointly by the parties and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any of the provisions of this Agreement.

 17. Resignation as Officer and Director. In the event that Employee’s employment with Employer is terminated for any reason whatsoever,
Employee agrees to immediately resign from any position Employee may hold as an officer or director of, or on behalf of, Employer. 
 18. Limitation on
Authority. Without the express written consent of Employer, the Employee shall have no apparent or implied authority to: 
 (a) pledge
the credit of Employer or any of its employees; 

  
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 (b) bind the Employer under any contract, agreement, note, mortgage or otherwise; or 

(c) sell, mortgage, transfer or otherwise dispose of any assets of Employer. 

19. Notices. Any notices under this Agreement shall be given in writing in person or by registered or certified U.S. mail, postage prepaid, return
receipt requested, or by facsimile with confirmation, to the parties at their respective addresses set forth below, and such notices shall be deemed given when received or three (3) days after placed in the mail in the manner provided above.
Either party may change such party’s address for notice by giving notice as provided herein. 
  

							
	(a)	  	If to Employer:	  	With a copy to:	  	
		  	Robert Nowinski, Ph.D.	  		  	
		  	28 Wells Avenue	  		  	
		  	Yonkers, NY 10701	  		  	
				
	(b)	  	If to Employee:	  		  	
		  	David Huang, M.D.	  		  	
		  	320 E 46th Street #23C	  		  	
		  	New York, NY 10017	  		  	

 20. Prior Agreements. Employee represents to Employer that (a) there are no restrictions, agreements or
understandings to which Employee is a party that would prevent or make unlawful Employee’s execution of this Agreement or Employee’s employment hereunder, (b) Employee’s execution of this Agreement and Employee’s employment
hereunder shall not constitute a breach of any contract, agreement or understanding, oral or written, to which Employee is a party or by which Employee is bound, (c) Employee is free and able to execute this Agreement and to enter into
employment by Employer, and (d) Employee shall not divulge to Employer any trade secrets or proprietary information that belongs to any other person or entity. 

21. No Assignment. This Agreement and the rights and obligations of both parties hereunder are personal in nature, and shall not be assignable by
either party hereto, except by operation of law. Notwithstanding the foregoing, Employer may assign some or all of its rights hereunder to a successor in interest. 

22. Headings. Headings used in this Agreement are solely for the convenience of the parties and shall be given no effect in the construction or
interpretation of this Agreement. 

  
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 23 Miscellaneous. 

(a) Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be deemed to be an original as against any
party whose signature appears thereon, and all of which shall together constitute one and the same instrument. This Agreement shall become binding when one or more counterparts hereof, individually or taken together, shall bear the signatures of all
of the parties reflected hereon as the signatories. 
 (b) Provisions Separable. The provisions of this Agreement are independent of and
separable from each other, and no provision shall be affected or rendered invalid or unenforceable by virtue of the fact that for any reason any other or others of them may be invalid or unenforceable in whole or in part. 

(c) Survival. Any provisions of this Agreement which, by their terms, are intended to survive the expiration or termination of this Agreement,
including but not limited to the restrictive covenant and the provisions relating to non-solicitation, confidentiality, and both parties agree to forever waive any claim or defense, at law or in equity, asserting that such provision(s) terminated or
otherwise became unenforceable as a result of the expiration or termination of this Agreement. 
 IN WITNESS WHEREOF, the parties hereto
have caused this Agreement to be signed and delivered as of the day and year set forth below. 
  

			
	CONTRAFECT CORPORATION
		
	By:	 	 





		 	Robert Nowinski, CEO
	Dated:	 	June 27, 2011
		
		 	 





		 	David Huang, M.D.
	Dated:	 	June 30, 2011


  
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