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                            Library & Multimedia
 Match statistics for sequence-based alleles in profiles from forensic PCR-mps kits
NCJ Number
              305081
Journal

*Electrophoresis* Volume: 42 Issue: 6 Dated: 2021 Pages: 756-765
Author(s)
          B. Young;
                        et al
Date Published

2021
Length
              10 pages
Annotation
              We describe a procedure to address calculation of match probabilities when casework samples are generated using an MPS kit with different trim sites than those present in the relevant population frequency database.
Abstract
              The first autosomal sequence-based allele (aka SNP-STR haplotype) frequency database for forensic massively parallel sequencing (MPS) has been published, thereby removing one of the remaining barriers to implementing MPS in casework. The database was developed using a specific set of flank trim sites. If different trim sites or different kits with different primers are used for casework, then SNP-STR haplotypes may be detected that do not have frequencies in the database. The proposed procedure provides a framework for comparison of any MPS kit or database combination while also accommodating comparison of MPS and CE profiles. (Publisher abstract provided)
      
  
          Additional Details
Grant Number(s)
        2018-DU-BX-0202


  
  
        
  Agencies
        NIJ-Sponsored


  
  
        
  Publication Type
        Research (Applied/Empirical)


  
  
        
  Award
        A fully continuous machine learning approach to predict the number of contributors in sequence-based DNA profiles
    
  
  
Date Published: January 1, 2021
    
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      PatentsRelated Topics
        
                Forensic sciences
        Evidence analysis and processing
        DNA (Deoxyribonucleic Acid)
        Databases
        Research and Development in Forensic Science for Criminal Justice Purposes



  
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