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Exhibit 31.1

CERTIFICATION PURSUANT TOSECTION 302 OF THE SARBANES-OXLEY ACT OF 2002

I, Dr. Amnon Gonenne, certify that:

|1. | I have reviewed this quarterly report on Form 10-Q of
      MabCure Inc.;                                                                                                                                                                                                                                                                             
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|   |                                                                                                                                                                                                                                                                                                                                                       
|2. | Based on my knowledge, this quarterly report does not
      contain any untrue statement of a material fact or omit to state a
      material fact necessary to make the statements made, in light of the
      circumstances under which such statements were made, not misleading with
      respect to the period covered by this quarterly report;
|   |                                                                                                                                                                                                                                                                                                                                                       
|3. | Based on my knowledge, the financial statements, and
      other financial information included in this quarterly report, fairly
      present in all material respects the financial condition, results of
      operations and cash flows of the registrant as of, and for, the periods
      presented in this quarterly report;                   
|   |                                                                                                                                                                                                                                                                                                                                                       
|4. | Our companys other certifying officer and I are
      responsible for establishing and maintaining disclosure controls and
      procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and
      internal control over financial reporting (as defined in Exchange Act
      Rules 13a-15(f) and 15d-15(f)) for our company and have:
|   |                                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                                   
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|   | (b)                                                                                                                                                                                                                                                                                                                                                   
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|   | (c)                                                                                                                                                                                                                                                                                                                                                   
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|   | (d)                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                       
|5. | Our companys other certifying officer and I have
      disclosed, based on our companys most recent evaluation of internal
      control over financial reporting, to our companys auditors and our
      companys audit committee or board of directors (or persons performing the
      equivalent functions):                                  
|   |                                                                                                                                                                                                                                                                                                                                                       
|   | (a)                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                                   

|Date:  | May 14, 2010                                | 
|------ | ------------------------------------------- | 
|       |                                             | 
|By:    | /s/ Dr. Amnon Gonenne                       | 
|Name:  | Dr. Amnon Gonenne                           | 
|Title: | President and Chief Executive
      Officer | 
|       | (Principal
      Executive Officer)         | 

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