<PAGE>
 
                                                          Confidential Treatment
                                                                   Exhibit 10.47

Redacted information, denoted as "[REDACTED]," has been omitted from this 
document pursuant to a request for confidential treatment that has been 
separately filed with the Commission.



                              COPROMOTION AGREEMENT


                  This COPROMOTION AGREEMENT is made as of the Effective Date
(defined below), by and between APOTHECON, INC., a wholly-owned subsidiary of
Bristol-Myers Squibb Company ("BMS"), having a place of business at 777 Scudders
Mill Road, Plainsboro, New Jersey 08536 ("APOTHECON"), and WARNER CHILCOTT INC.,
having a place of business at Rockaway 80 Corporate Center, 100 Enterprise
Drive, Suite 280, Rockaway, New Jersey 07866 ("WCI").

                             W I T N E S S E T H:

                  WHEREAS, APOTHECON markets and distributes norethindrone and
ethinyl estradiol tablets, USP, under the trademark Ovcon(R)35; and

                  WHEREAS, APOTHECON also markets and distributes Estradiol
Vaginal Cream, USP, 0.01%, under the trademark Estrace(R); and

                  WHEREAS, WCI is engaged in the business of marketing
pharmaceutical products to physicians; and

                  WHEREAS, APOTHECON wishes to expand the promotion of
Ovcon(R)35 and Estrace(R) cream to physicians, and WCI desires to have the right
to copromote said products, upon the terms specified herein.

                  NOW, THEREFORE, in consideration of the mutual covenants
herein set forth, and intending to be legally bound hereby, the parties hereto
agree as follows:

                  1.       Definitions. For purposes of this Agreement, the
following terms shall have the corresponding meanings set forth below:

                  "Affiliate" means, with respect to any Person, any other
Person which directly or indirectly controls, is controlled by, or is under
common control with, such Person. A Person shall be regarded as in control of
another Person if it/he/she owns, or directly or indirectly controls, more than
fifty percent (50%) of the voting securities (or comparable equity interests) or
other ownership interests of the other Person, or if it/he/she directly or
indirectly possesses the power to direct or cause the direction of the
management or policies of the other Person, whether through the ownership of
voting securities, by contract or any other means whatsoever.

                  "Agreement" means this agreement, together with all
appendices, exhibits and schedules hereto, and as the same may be amended or
supplemented from time to time hereafter by a written agreement duly executed by
authorized representatives of each party hereto.
<PAGE>
 
                  "Agreement Quarter" means each three-month period commencing
on the first day of January, April, July, or October, as the case may be, during
the Copromotion Term.

                  "Agreement Year" means each 12-month period commencing on the
Effective Date and each anniversary thereof during the Copromotion Term.

                  "Call List" shall have the meanings specified in Section 5
hereof.

                  "Confidential and Proprietary Information" has the meaning set
forth in Section 14 hereof.

                  "Copromotion Term" has the meaning specified in Section 12(a)
hereof.

                  "Estrace(R)" means all current presentations of estradiol
vaginal cream, USP, 0.01%, currently approved by the FDA for the treatment of
vulval and vaginal atrophy (as more fully specified in the labeling for the
product) and marketed under the trademark Estrace(R). For the avoidance of
doubt, any line extensions of Estrace(R) cream developed and introduced by WCI
pursuant to separate license agreements between WCI and APOTHECON are
specifically excluded from the definition of "Estrace(R)".

                  "Effective Date" of this Agreement means January 1, 1999.

                  "Manufacturing Cost" means, with respect to samples of the
Products, the cost to BMS of raw materials, component costs, energy, labor
(salary and benefits) and reasonable overhead charges relating to the
manufacture of a specified quantity of either of Products, and other direct and
allocable indirect costs to manufacture such product, including but not limited
to manufacturing charges for material adjustments, for offgrade or defective
material, handling losses, physical adjustments, salvage and start-up costs, and
charges in the nature of depreciation and amortization of capitalized costs of
manufacturing equipment and facilities, all consistently applied in accordance
with U.S. GAAP. If either of the Products is manufactured by a third party, the
costs shall be the amount paid by APOTHECON for such Products, plus any of the
aforementioned costs that are incurred in completing the testing, manufacture,
packaging and delivery of the Products.

                  "Marketing Plan" has the meaning specified in Section 5
hereof.

                  "National Marketing Team" or "NMT" has the meaning specified
in Section 5 hereof.

                  "Net Sales" means for the applicable period the gross amount
invoiced for the Products by APOTHECON or its licensees to unAffiliated third
parties in the Territory, less the following amounts to the extent deducted on
such invoice or absorbed by APOTHECON in accordance with U.S. GAAP: (i)
quantity, trade, and/or cash discounts, allowances, rebates, and price
adjustments or reductions allowed or given, provided however that such
discounts, allowances, rebates, adjustments and reductions are ordinary and
usual in the industry; (ii) freight, postage and shipping insurance expenses
absorbed by APOTHECON and not reimbursed by the invoicee; (iii) credits,
rebates, chargebacks, or refunds allowed for rejected, outdated or returned
Products; (iv) sales and other excise taxes and duties directly related to the
sale, to the extent that such items are 

                                      -2-
<PAGE>
 
included in the gross invoice price (but not including taxes assessed against
the income derived from such sale). If Products are sold for compensation other
than cash, Net Sales shall be calculated based on the fair market value of the
Products in cash.

                  "Ovcon(R)35" means all current presentations of norethindrone
and ethinyl estradiol tablets, USP, currently approved by the FDA as an oral
contraceptive (as more fully specified in the labeling for the product) and
marketed under the trademark "Ovcon(R)35".

                  "Person" shall mean an individual, corporation, partnership,
limited liability company, trust, business trust, association, joint stock
company, joint venture, pool, syndicate, sole proprietorship, unincorporated
organization, governmental authority, or any other form of entity not
specifically listed herein.

                  "Physician" means any physician or other health care
professional authorized by applicable law to prescribe Ovcon(R)35 or Estrace(R).

                  "Products" means Ovcon(R)35 and Estrace(R) and any other
product the parties may mutually agree to add to this Agreement, which addition
shall be set forth in writing and appended to this Agreement.

                  "Serious adverse event" and "Non-serious adverse event" have
the meanings set forth in section 8(h) hereof.

                  "Territory" means the United States of America, and
specifically excluding Puerto Rico and any U.S. held territories and
possessions.

                  "Trademarks" means the trademarks "Ovcon(R)35" and
"Estrace(R)" and any other trademarks or trade names (whether registered or
unregistered) that APOTHECON decides to use on or with either of the Products or
in any promotional material related to either of the Products in the Territory
during the Copromotion Term.

                  2.  Grant of Rights to WCI.

                  (a) APOTHECON hereby engages WCI, on an exclusive basis (even
as to APOTHECON), to promote the Products to Physicians in the Territory during
the Copromotion Term, upon the terms and conditions set forth in this Agreement.
APOTHECON reserves all rights not expressly granted hereunder, including,
without limitation, the right to promote the Products to Persons other than
Physicians, including, without limitation, the managed care trade. It is
understood and agreed by the parties that WCI may promote the Products itself or
through any of its Affiliates, provided that such Affiliates agree to be bound
by all the terms and conditions of this Agreement.

                  (b) APOTHECON hereby grants to WCI a fully-paid up,
nonexclusive right and license to use the Trademarks during the Copromotion Term
solely in connection with the promotion of the Products in the Territory in
accordance with this Agreement. WCI shall not grant any sublicenses with respect
to the Trademarks without the prior, express written consent of APOTHECON;
except that WCI is hereby authorized to grant sublicenses to use the Trademarks

                                      -3-
<PAGE>
 
to its Affiliates if such Affiliates are utilized to promote the Products in
accordance with Section 2(a) herein and provided that such Affiliates agree to
be bound by all the terms and conditions of this Agreement.

                  (c) WCI acknowledges that BMS is the sole and exclusive owner
of all right, title and interest in and to the Trademarks (including the
application and any subsequent registrations and renewals thereof). In
connection with its use of the Trademarks, WCI shall not in any way or manner
represent to others that it owns or has any ownership rights in the Trademarks
and any subsequent registrations thereof. WCI agrees and acknowledges that any
goodwill accruing or arising from its use of the Trademarks shall be for the
sole benefit of APOTHECON and/or BMS. WCI shall not take any action that
impairs, contests or tends to impair or contest APOTHECON's and/or BMS's right,
title and interest in and to the Trademarks and any goodwill associated with the
Trademarks. All rights to use the Trademarks not expressly granted to WCI by BMS
pursuant this Agreement are reserved.

                  (d) WCI shall not use or display any other mark or marks in
connection with the Trademarks, except for trademarks used or adopted by WCI
generally, such as "Warner Chilcott" or the "WC" logo, that are used on
packaging and/or advertising or promotional material for the Products and that
are physically separate from the Trademarks. Notwithstanding the foregoing
exception, WCI shall not use or adopt any variation of the Trademarks or any
word or mark that is confusingly similar to the Trademarks. WCI shall comply
with the terms and conditions of this Agreement and all federal and state laws,
statutes and regulations in connection with its use of the Trademarks.

                  (e) APOTHECON and its Affiliates shall be responsible, at
their own cost and expense, for taking all actions required for the application,
registration, maintenance and renewal of the Trademarks in the United States
Patent and Trademark Office. BMS shall not permit any U.S. registration for the
Trademarks to lapse or become abandoned. WCI shall furnish APOTHECON with all
information reasonably requested by APOTHECON (including specimens and samples
illustrating the manner of use of the Trademarks) and documents (including the
execution and delivery of any and all affidavits, declarations, oaths and other
documents) to assist APOTHECON and its Affiliates in maintaining trademark
protection and registrations for the Trademarks.

                  (f) WCI shall promptly notify APOTHECON of: (i) any actual or
suspected infringement or misuse of the Trademarks, or (ii) any information
which may adversely affect the Trademarks. If either of the Trademarks is
infringed by a Third Party, APOTHECON and its Affiliates shall have the right
and option, but not the obligation, to bring an action for infringement, at
their sole expense, against the Third Party, and/or reach a settlement with the
Third Party. Except as may be otherwise set forth in any license agreement
between APOTHECON or its Affiliates and WCI or its Affiliates concerning the
"Ovcon(R)" or "Estrace(R)" trademark, the proceeds of any recovery resulting
from an infringement action against and/or settlement with a Third Party shall
belong to APOTHECON.

                                      -4-
<PAGE>
 
                  3.  Copromotion by WCI.

                  (a) WCI shall use best efforts, within the standard of
commercial reasonableness, to diligently promote the Products in the Territory
to Physicians in accordance with the terms of this Agreement during the
Copromotion Term; provided, that such efforts shall not be less than those that
it employs to promote its other principal products to Physicians, including, at
a minimum, the efforts undertaken to promote [REDACTED]; and provided, further,
that WCI's sales force shall make the position details set forth in the
Marketing Plan.

                  (b) Except as provided for in Section 6 of this Agreement or
otherwise agreed to by the parties and subject to the terms and conditions of
this Agreement, WCI shall be solely responsible for the costs and expenses of
establishing, maintaining and training its sales force and conducting its other
activities under this Agreement, provided, however, that the contents and
strategic direction of any training provided by WCI that relates to the Products
shall be coordinated and agreed to by APOTHECON.

                  (c) WCI shall provide APOTHECON, within five (5) working days
of transmission, complete copies and/or transcripts of all home office generated
(for example, those sent out by WCI's Sales, Marketing and Sales Training
departments) communications (whether written, electronic or visual aids) to any
of WCI's sales representatives concerning the promotion of the Products. The
individual to which these shall be sent will be designated by APOTHECON upon
execution of this Agreement. In addition, all written, electronic and visual
communications provided to any of WCI sales representatives regarding strategy,
positioning or selling messages for the Products will be subject to prior review
and approval by APOTHECON.

                  (d) APOTHECON shall retain sole responsibility for contractual
and other relationships with managed care organizations, formularies, insurers,
and governmental agencies and instrumentalities (including without limitation
Medicare, Medicaid, the Veterans Administration, and military entities).

                  (e) During the Copromotion Term and for [REDACTED] months
thereafter, WCI shall not market, promote or otherwise sell any [REDACTED] or
[REDACTED] product other than the Products, provided however, that this
subsection (e) shall not apply to any line extensions of Ovcon(R) or Estrace(R)
that WCI may obtain rights to pursuant to separate license agreements with
APOTHECON.

                  4.  Responsibilities of APOTHECON.

                  (a) APOTHECON shall have the sole authority to determine the
price of the Products, including price increases or decreases and the timing
thereof as determined by APOTHECON in its sole discretion. APOTHECON will
consult with WCI prior to implementing any price change, but such consultation
shall not restrict or limit APOTHECON's sole authority and discretion to
implement changes.

                  (b) APOTHECON shall have the sole responsibility, at its cost
and expense, for the manufacture, shipping, distribution and warehousing of the
Products, for the invoicing and 

                                      -5-
<PAGE>
 
billing of purchasers of the Products, for order confirmation (if any) in
accordance with APOTHECON customary practices, and for the collection of
receivables resulting from Net Sales. APOTHECON will book all sales of the
Products. All sales will be deemed made pursuant to contract between APOTHECON
and the customer.

                  (c) APOTHECON shall use commercially reasonable efforts,
including maintaining reasonable levels of inventory in light of customary
industry practice, to ensure that sufficient stock of the Products will be
available in its inventory to fill orders from the trade in accordance with
normal industry practices.

                  (d) APOTHECON shall use reasonable efforts consistent with
applicable legal requirements to maintain all necessary authorizations with the
FDA to manufacture and market the Products in the Territory. WCI shall refrain
from engaging in any act or omission inconsistent with such legal requirements.

                  (e) Subject to Section 15, APOTHECON reserves the right to
assign to a third party (by sale, license or otherwise) all rights to either of
the Products (including the IND and NDA), as and upon such terms as APOTHECON
may elect and determine in its sole and absolute discretion.

                  5.  National Marketing Team.

                  (a) A committee for marketing and promoting the Products to
Physicians in the Territory will be established promptly by APOTHECON and WCI
after execution of this Agreement (such committee being referred to herein as
the "National Marketing Team" or the "NMT"). The National Marketing Team shall
be composed of four (4) persons, with APOTHECON and WCI each being entitled to
designate two (2) individuals. The initial members shall be designated by each
party in writing promptly following execution of this Agreement. Each party may
change its designated members at any time upon advance written notice to the
other party.

                  (b) WCI shall present a marketing plan for the Products to the
NMT for review and approval not less frequently than annually covering a period
not to exceed one year. Each marketing plan shall include a list of Physicians
to whom the Products will be promoted during the period covered by the Marketing
Plan (the "Call List"). Each marketing plan shall identify the direct selling
and marketing activities to be conducted by WCI in each Agreement Quarter
covered by the Marketing Plan, including the product sampling levels and
scheduling. The marketing plan shall be subject to final review and written
approval by APOTHECON (the marketing plan so approved being referred to herein
as the "Marketing Plan"). Each Marketing Plan shall remain in effect until a new
Marketing Plan is again so approved by APOTHECON. Deviations from an approved
Marketing Plan will require resubmission to and approval by APOTHECON.

                  (c) Subject to final review by and written approval from
APOTHECON, the NMT shall also be responsible for:

                           (i)      developing and revising existing and new
         promotional materials for the Products for in-person promotion to
         Physicians, including the package inserts, labeling 

                                      -6-
<PAGE>
 
         and other materials to the extent that the same relate specifically to
         the marketing of the Products to Physicians;

                           (ii)     developing promotional programs for the
         Products to Physicians;

                           (iii)    planning market research activities;

                           (iv)     preparing any new materials directly related
         to the Products that are to be used to train WCI's sales force;

                           (v)      planning symposia, seminars and other
         professional relations events of specific interest to Physicians; and

                           (vi)     determining the types and frequency of
         reports to be provided by WCI to APOTHECON with respect to WCI's
         undertakings under this Agreement.

                  (d) The NMT shall meet not less than once in each Agreement
Quarter during the Copromotion Term or as otherwise agreed by the parties in
writing, at such locations as are designated by each party alternatingly. Each
party shall bear the costs and expenses of its designated members that are
incurred in connection with the National Marketing Committee meetings.

                  (e) Notwithstanding anything in this Section 5 or that might
otherwise imply to the contrary in this Agreement, APOTHECON shall have
strategic responsibility and sole authority and responsibility for obtaining all
legal, regulatory and medical approvals related to the selling and use of all
promotional materials prepared or approved by the National Marketing Team.

                  6.  Funding of Promotional Activities.

                  (a) During the Copromotion Term, and subject to Sections 6(b)
and 7 (in the case of product samples), APOTHECON will produce and provide to
WCI those quantities of promotional, sales, marketing and educational materials
specified in the Marketing Plan and approved by APOTHECON ("Sales Materials"),
as well as those quantities of samples of the Products specified in the
Marketing Plan.

                  (b) APOTHECON shall fund the cost of the Sales Materials
(development and production costs only) and product samples referenced in
Section 6(a) in an amount not to exceed [REDACTED] for each Agreement Year,
provided, however, that: (i) in the event that the combined Net Sales of the
Products in any Agreement Year shall be less than the combined Net Sales of the
Products in [REDACTED], then APOTHECON'S funding obligation pursuant to this
Section 6(b) in the immediately following year shall decrease by the percentage
decline of combined Net Sales of the Products measured against combined Net
Sales of the Products in [REDACTED]; and (ii) in the event that the Agreement is
terminated with respect to either Ovcon(R)35 or Estrace(R), then APOTHECON's
funding obligation pursuant to this Section 6(b) shall be decreased for the
remainder of the Copromotion Term by a percentage calculated by dividing the
amount of the

                                      -7-
<PAGE>
 
terminated product's Net Sales by the Products' combined Net Sales, each for the
twelve (12) months preceding the termination, and multiplying the resulting
quotient by one hundred (100).

                  (c) For purposes of accounting for APOTHECON's funding
obligation under Section 6(b), the cost of the Sales Materials shall be
[REDACTED], and the cost of the product samples shall be [REDACTED].

                  (d) Except for APOTHECON's funding obligation as set forth in
section 6(b) hereof, WCI shall be solely responsible for all costs incurred in
the promotion of the Products to Physicians in the Territory. WCI may, at its
own expense, purchase from APOTHECON Sales Materials and/or product samples in
quantities in excess of the amounts that APOTHECON is required to fund pursuant
to Section 6(b), provided, however, that if the amounts so purchased are in
excess of those set forth in the Marketing Plan, WCI shall provide APOTHECON
with sufficient notice of its intent to make such purchases as to enable
APOTHECON to supply the requested Sales Materials and/or product samples.

                  (e) APOTHECON shall invoice the purchase price of the Sales
Materials and/or product samples to WCI at the price specified in Section 6(c)
above. WCI shall pay for such Sales Materials and/or product samples within
[REDACTED] days after receipt of same by WCI, or shall credit same against such
amount as may then be remaining under APOTHECON's annual funding obligation
under Section 6(b).

                  (f) APOTHECON shall be under no obligation to conduct or
develop symposia, seminars, technical and scientific exhibits and other
professional relations events with respect to the Products or to conduct
additional Phase I, II, III or IV clinical trials with respect to the Products.
If requested by WCI and approved by APOTHECON in writing:

                           (i)     WCI may conduct or develop symposia,
         seminars, technical and scientific exhibits and other professional
         relations events with respect to the Products; and

                           (ii)    WCI may conduct additional Phase IV clinical
         trials with respect to the use of the Products, provided that APOTHECON
         and its Affiliates shall have the exclusive right to use for any
         purpose the data resulting from any such clinical studies including,
         but not limited to, product registrations and product licenses related
         to the Products, throughout the world.

WCI shall be solely responsible for all costs or expenses incurred by WCI or
APOTHECON pursuant to clauses (i) and (ii) of this Section 6(f), and APOTHECON
shall have no contribution or reimbursement obligation hereunder with respect to
same.

                  7.  Product Samples; Additional Clinical Studies.

                  (a) Product samples supplied by APOTHECON to WCI pursuant to
Section 6 will by used solely in making detail calls to Physicians in the
Territory. Product samples will in all cases be shipped to WCI on not less than
sixty (60) days' advance written notice and subject to the prevailing shipping
schedules of APOTHECON.

                                      -8-
<PAGE>
 
                  (b) Product samples will be shipped to a WCI central
distribution point from which WCI will further distribute them to its sales
representatives. All costs of such distribution by WCI shall be borne solely by
WCI. Once WCI accepts shipment of product samples from APOTHECON, WCI shall be
responsible for all product samples accountability and compliance with the
Prescription Drug Marketing Act, as amended, and other applicable federal, state
and local laws relating to samples. WCI is further responsible for adherence by
its sales representatives to such laws.

                  (c) Product samples shall have a shelf life of not less than
[REDACTED] months.

                  8.  Certain Regulatory Matters.

                  (a) All regulatory matters regarding the Products shall remain
under the exclusive control of APOTHECON, subject to the participation by WCI in
matters related to the marketing of the Products to Physicians in the Territory.
APOTHECON will have the sole responsibility, at its cost and expense, to respond
to products and medical complaints and to handle all returns and recalls of the
Products.

                  (b) APOTHECON shall furnish WCI with efficacy and safety
information reasonably requested by WCI to assist it in promoting the Products
to Physicians, including, without limitation, relevant clinical and safety data
included in the New Drug Application for the Products and information related to
the efficacy and safety profile of the Products since their approval by the FDA.
Such information shall be treated as Confidential Information of APOTHECON, and
shall not be disclosed to third parties or used for any purpose other than WCI's
performance of its obligations under this Agreement without APOTHECON's prior
written approval.

                  (c) Beginning as of the Effective Date of this Agreement, each
party shall promptly notify the other party of any significant event(s) that
affect the marketing of the Products, including, but not limited to, adverse
drug experiences and governmental inquiries, whether within or outside the
Territory.

                  Serious adverse events for the Products (as defined in section
8(h) below) learned by WCI shall be submitted to APOTHECON within three (3)
working days but no more than four (4) calendar days from the receipt date by
WCI.

                  Non-serious adverse events for the Products (as defined in
section 8(h) below) that are spontaneously reported to WCI shall be submitted to
APOTHECON no more than one (1) month from the date received by WCI; provided,
however, that medical and scientific judgment should be exercised in deciding
whether expedited reporting is appropriate in other situations, such as
important medical events that may not be immediately life-threatening or result
in death or hospitalization but may jeopardize the patient or may require
intervention to prevent a serious adverse event outcome.

                  APOTHECON shall have the reporting responsibility for such
events to applicable regulatory health authorities anywhere in the world.

                                      -9-
<PAGE>
 
                  WCI shall report all such adverse events involving the
Products learned by it to:

                  Vice President, Worldwide Safety & Surveillance
                  Bristol-Myers Squibb Company
                  P.O. Box 5400
                  Mail Stop HW19-1.01
                  Princeton, New Jersey 08543-5400
                  U.S.A.

[REDACTED]

A CIOMS-I form or a form that contains the data elements of a CIOMS-I form is
recommended.

                  Serious adverse events concerning the Products learned by
APOTHECON shall be reported by APOTHECON to WCI at the time that APOTHECON
reports such events to FDA, and shall be sent to:

                  Vice President B Regulatory Affairs
                  Warner Chilcott, Inc.
                  100 Enterprise Drive B Suite 280
                  Rockaway, NJ 07866

[REDACTED]

                  (d) Beginning as of the Effective Date of this Agreement, each
party shall promptly notify the other party in writing of any order, request or
directive of a court or other governmental authority to recall or withdraw
either of the Products in any jurisdiction. APOTHECON shall be responsible, at
its sole cost and expense, for the costs of any recall or withdrawal of the
Products.

                  (e) Upon being contacted by the Food and Drug Administration
(FDA) or any other federal, state or local agency for any regulatory purpose
pertaining to this Agreement or to the Products, WCI shall, if not prohibited by
applicable law, immediately notify APOTHECON and will not respond to the agency
until consulting with APOTHECON, to the maximum feasible extent; provided,
however, that the foregoing shall not be construed to prevent WCI in any way
from complying, and WCI may permit unannounced FDA or similar inspections
authorized by law and respond to the extent necessary to comply, with its
obligation under applicable law.

                  (f) WCI shall inform Bristol Myers Squibb Company's office of
the Vice President, Worldwide Safety & Surveillance of any Product Quality
Complaint received within three (3) working days but no more than four (4)
calendar days from the receipt date by WCI. A Product Quality Complaint is
defined as any complaint that questions the purity, identity, potency or quality
of either of the Products, its packaging, or labeling, or any complaint that
concerns any incident that causes the drug product or its labeling to be
mistaken for, or applied to, another article or any bacteriological
contamination, or any significant chemical, physical, or other change or
deterioration in the distributed drug product, or any failure of one or more
distributed batches of the drug product 

                                      -10-
<PAGE>
 
to meet the specifications therefor in the NDA for the Products. Such
information shall be sent to the same address as set forth in Section 8(c) above

                  (g) BMS Professional Services Department shall handle all
medical inquiries concerning the Products. WCI shall refer all routine medical
information requests in writing to:

                  Bristol-Myers Squibb Company
                  Professional Services Department
                  P.O. Box 4500 P15-01
                  Princeton, NJ 08543-4500

Urgent medical information requests shall be referred by telephone to:
Professional Services Department: [REDACTED]

                  (h) A "serious" adverse event for the Products is defined as
any untoward medical occurrence that at any dose for either of the Products: (i)
results in death; (ii) is life-threatening; (iii) requires inpatient
hospitalization or prolongation of existing hospitalization; (iv) results in
persistent or significant disability/incapacity; (v) is a congenital
anomaly/birth defect; (vi) results in drug dependency or drug abuse; (vii) is
cancer, or (viii) is an overdose. A "nonserious" adverse event is defined as
that which is not serious.

                  9.  Compliance with Law and Labeling.

                  (a) Each party shall maintain in full force and effect all
necessary licenses, permits and other authorizations required by law to carry
out its duties and obligations under this Agreement. Each party shall comply
with all laws, ordinances, rules and regulations (collectively, "Laws")
applicable to its activities under this Agreement, including without limitation,
any requirements of any product license applicable to the Products in the
Territory; provided, however, that WCI shall be solely responsible for
compliance with those Laws pertaining to the activities conducted by it
hereunder (including, without limitation, those Laws that apply to documentation
and records retention pertaining to the distribution and use of product samples
by it under this Agreement), notwithstanding that the FDA may, as a matter of
law, be entitled to hold APOTHECON accountable or responsible (whether primarily
or secondarily) for failure of WCI to comply with such Laws. The parties will
reasonably cooperate with one another with the goal of ensuring full compliance
with Laws.

                  (b) WCI shall make no representations or warranties relative
to either of the Products that conflict or are inconsistent with the
FDA-approved label for the respective Products. WCI shall be responsible for any
documented out-of-pocket costs incurred by APOTHECON resulting from statements
made by its sales representatives that relate to the safety or efficacy of the
Products that are not in compliance with applicable law or have not been
authorized by APOTHECON in advance in writing.

                  (c) The parties acknowledge to each other that the breach of
any obligation contained in this Section 9 shall constitute a material breach of
the Agreement. The parties further agree that the absence of a similar
materiality acknowledgement for another Section in this 

                                      -11-
<PAGE>
 
Agreement shall not be evidential as to whether a breach of such Section or of
any other aspect of this Agreement constitutes a material breach.

                  10. Copromotion Compensation.

                  As compensation for services rendered by WCI during the
Copromotion Term, APOTHECON shall pay WCI a "Performance Fee" based on Net Sales
as set forth on Schedule A (as to Ovcon(R)35) and Schedule B (as to Estrace(R)).

                  11. Payments and Reporting.

                  (a) APOTHECON shall furnish WCI, within fifteen (15) days
after each month, a report setting forth in reasonable detail the calculation of
WCI's compensation under Section 10 with respect to such period, including the
calculation of gross to net sales (and, in addition to a report for December, a
report with respect to the entire Agreement Year).

                  (b) Compensation due WCI (or payments due APOTHECON) under
Section 10 shall be paid within [REDACTED] days after each Agreement Quarter.

                  (c) The parties will maintain complete and accurate books and
records in sufficient detail to enable verification of WCI's performance
hereunder and the basis for calculating the compensation paid by APOTHECON to
WCI hereunder. Either party may demand an audit of the other party's relevant
books and records in order to verify the other's reports on the aforesaid
matters. Upon reasonable prior notice to the party to be audited, the
independent public accountants of the other party shall have access to the
relevant books and records of the party to be audited in order to conduct a
review or audit thereof. Such access shall be available during normal business
hours not more than once each calendar quarter during the Copromotion Term and
only for a period until two years after the relevant period in question. The
accountants shall be entitled to report its conclusions and calculations to the
party requesting the audit, except that in no event shall the accountants
disclose the names of customers of either party or the prices, discounts,
rebates, or other terms of sale charged by APOTHECON for the Products.

                  The party requesting the audit shall bear the full cost of the
performance of any such audit except as hereinafter set forth. If, as a result
of any inspection of the books and records of APOTHECON, it is shown that
APOTHECON's payments to WCI under this Agreement were less than the amount which
should have been paid, then APOTHECON shall make all payments required to be
made to eliminate any discrepancy revealed by said inspection within 30 days
after WCI's demand therefor. If, as a result of any inspection of the books and
records of WCI, it is shown that APOTHECON's funding of costs associated with
its funding obligations under this Agreement were more than the amount which
should have been paid, then WCI shall reimburse APOTHECON for the discrepancy
revealed by said inspection within 30 days after APOTHECON's demand therefor.
Furthermore, if the payments were more or less than the amount which should have
been paid by an amount in excess of [REDACTED] percent [REDACTED] of the
payments actually made during the period in question, the party responsible for
the discrepancy shall also reimburse the auditing party for its documented
out-of-pocket costs of such inspection.

                                      -12-
<PAGE>
 
                  12. Copromotion Term and Termination.

                  (a) The Copromotion Term shall be for five (5) years and shall
begin effective January 1, 1999 (even if the Agreement is executed after such
date) and shall end on December 31, 2003, unless terminated earlier in
accordance with Section 12(b), (c) or (d) below or unless extended pursuant to
section 12(g) by the parties' mutual agreement (the "Copromotion Term").

                  (b) Upon sixty (60) days written notice to WCI, APOTHECON may
terminate the Copromotion Term without penalty with respect to Ovcon(R)35 or
Estrace(R) upon the occurrence of any of the following:

                           (i)     total prescriptions for such product in any
         Agreement Year do not exceed [REDACTED] percent [REDACTED] of the
         respective base prescription levels for such product set forth on
         Schedule C attached hereto; or

                           (ii)    total prescriptions for such product in any
         two (2) consecutive Agreement Quarters do not exceed the sum of the
         respective base prescription levels for such product set forth on
         Schedule C attached hereto; or

                           (iii)   APOTHECON sells or out-licenses Ovcon(R)35 or
         Estrace(R) Cream to an unAfilliated third party (so long as such sale
         or out-license is in accordance with Section 15 herein), or all of the
         outstanding stock or all or substantially all of the business assets of
         APOTHECON are sold to an unAffiliated third party, provided that in
         either such event APOTHECON shall pay to WCI an amount equal to the
         Performance Fee earned by WCI with respect to each such sold or out-
         licensed product to the date of termination plus an amount equal to
         [REDACTED] of the aggregate Performance Fee earned by WCI with respect
         to each such sold or out-licensed product for the four full calendar
         quarters immediately preceding the quarter in which the date of
         termination occurs; or

                           (iv)    BMS permanently stops manufacturing such
         product, provided that APOTHECON shall continue to provide the market
         with such product for eighteen (18) months from the date of the notice,
         and provided further, that APOTHECON will provide reasonable technical
         assistance to WCI if WCI wishes to transfer production to a third party
         acceptable to APOTHECON.

In all instances, prescription levels shall be as reported by the International
Marketing Services Prescription Reporting Services, or such other prescription
services to which the parties may mutually agree in writing.

                  (c) Upon written notice to WCI, APOTHECON may terminate the
Copromotion Term without penalty with respect to the Agreement in its entirety
upon the occurrence of either of the following:

                           (i)     [REDACTED] percent [REDACTED or more of the
         voting securities of WCI are sold or transferred or WCI otherwise
         undergoes a change of control; or

                                      -13-
<PAGE>
 
                           (ii)    WCI breaches any material obligation or duty
         under this Agreement and said breach is continuing thirty (30) days
         after APOTHECON has advised WCI in writing of the existence and nature
         of the breach; or

                           (iii)   APOTHECON receives notice that WCI has become
         insolvent or has suspended business in all material respects hereof, or
         has consented to an involuntary petition purporting to be pursuant to
         any reorganization or insolvency law of any jurisdiction, or has made
         an assignment for the benefit of creditors, or has applied for or
         consented to the appointment of a receiver or trustee for a substantial
         part of its property or assets.

                  (d) WCI may terminate the Copromotion Term without penalty
with respect to Ovcon(R)35 or Estrace(R) or with respect to the Agreement in its
entirety, as follows:

                           (i)     at any time, without cause, upon one hundred
         eighty (180) days written notice to APOTHECON; or

                           (ii)    APOTHECON breaches any material obligation or
         duty under this Agreement and said breach is continuing sixty (60) days
         after WCI has advised APOTHECON in writing of the existence and nature
         of the breach; or

                           (iii)   WCI receives notice that APOTHECON has become
         insolvent or has suspended business in all material respects hereof, or
         has consented to an involuntary petition purporting to be pursuant to
         any reorganization or insolvency law of any jurisdiction, or has made
         an assignment for the benefit of creditors, or has applied for or
         consented to the appointment of a receiver or trustee for a substantial
         part of its property or assets.

                  (e) Neither the termination nor expiration of the Copromotion
Term shall release or operate to discharge either party from (i) any liability
or obligation that may have accrued prior to such termination or expiration, or
(ii) any other agreement which may exist between the parties regarding line
extensions of the Products or any other product, except as may be set forth in
such other agreement. Any termination of the Copromotion Term by a party shall
not be an exclusive remedy, but shall be in addition to any legal or equitable
remedies that may be available to the terminating party. However, neither party
shall be liable to the other party for any damages (whether direct, indirect,
special, consequential, incidental, or other, including lost profits) sustained
by reason of expiration of this Agreement or for termination of this Agreement
by a party in accordance with the terms hereof.

                  (f) During any notice period, each party shall continue to
fulfill its obligations under this Agreement. Upon the termination or expiration
of the Copromotion Term, WCI shall promptly cease all of its promotion
activities pursuant to this Agreement, discontinue any use of the Trademarks,
return to APOTHECON all sales training, promotional, marketing material,
APOTHECON call lists and computer files, and any remaining product samples
(i.e., not already distributed or destroyed with destruction certified by WCI)
that may have been supplied to WCI by APOTHECON under this Agreement.

                                      -14-
<PAGE>
 
                  (g) The Copromotion Term may be extended at the expiration of
the initial Copromotion Term upon the mutual written consent of the parties.

                  13. Indemnification and Insurance.

                  (a) APOTHECON shall defend, indemnify and hold WCI and its
employees, agents, officers, directors and affiliates (a "WCI Party") harmless
from and against any and all losses, liabilities, obligations, claims, fees
(including, without limitation, attorneys fees), expenses and lawsuits incurred
by a WCI Party that are claimed by any third party and that result from or arise
in connection with (i) the breach of any covenant, representation or warranty of
APOTHECON contained in this Agreement, (ii) the manufacturing, storage, sale or
distribution of the Products by APOTHECON or any licensee or affiliate thereof,
including, without limitation, any claim of patent infringement, (iii) any
product liability claim related to the Products, including, without limitation,
the use by any person of any Products that were manufactured, sold or
distributed by APOTHECON or any licensee or affiliate thereof, (iv) any
contamination of or defect in the Products; and (v) breach by APOTHECON of its
obligations under Section 9 hereof. Notwithstanding anything in this Section
13(a), APOTHECON shall not be obligated to indemnify a WCI Party for any
liability related to the Products for which WCI has assumed an indemnification
obligation under Section 13(b) below.

                  (b) WCI shall defend, indemnify and hold APOTHECON and its
employees, agents, officers, directors and affiliates (an "APOTHECON Party")
harmless from and against any and all losses, liabilities, obligations, claims,
fees (including, without limitation, attorneys fees), expenses and lawsuits
brought against or incurred by an APOTHECON Party by a third party resulting
from or arising in connection with (i) the breach by WCI of any covenant,
representation or warranty of WCI contained in this Agreement, (ii) any
contamination, mislabeling, or adulteration of any product samples occurring
while such product samples are under the control of WCI, and/or (iii) breach by
WCI of its obligations under Section 9 hereof.

                  (c) To receive the benefits of the indemnity under clauses (a)
or (b) above, as applicable, an indemnified party must (i) give the indemnifying
party written notice of any claim or potential claim promptly after the
indemnified party receives notice of any such claim; (ii) allow the indemnifying
party to assume the control of the defense and settlement (including all
decisions relating to litigation, defense and appeal) of any such claim (so long
as it has confirmed its indemnification obligation to such indemnified party
under this Section 13); and (iii) so long as such cooperation does not vitiate
any legal privilege to which it is entitled, reasonably cooperate (provided the
indemnifying party reimburses the indemnified party's reasonable documented
out-of-pocket expenses) with the indemnifying party in its defense of the claim
(including, without limitation, making documents and records available for
review and copying and making persons within its/his/her control available for
pertinent testimony). If the indemnifying party defends the claim, an
indemnified party may participate in, but not control, the defense of such claim
at its/his/her sole cost and expense. An indemnifying party shall have no
liability under this Section 13 as to any claim for which settlement or
compromise of such claim or an offer of settlement or compromise of such claim
is made by an indemnified party without the prior consent of the indemnifying
party.

                                      -15-
<PAGE>
 
                  (d) WCI acknowledges and agrees that any WCI sales force
personnel (including contract sales personnel, telemarketers, independent
contractors, employees, and agents) used by WCI to fulfill its obligations under
this Agreement are not, and are not intended to be or be treated as, employees
of APOTHECON or any of its Affiliates, and that such individuals are not
eligible to participate in any "employee benefit plans", as such term is defined
in section 3(3) of ERISA, that are sponsored by BMS or any of its Affiliates.

                  APOTHECON shall not be responsible to WCI, to any employees,
agents, contractors, telemarketers, or other personnel of WCI used by it to
perform its obligations under this Agreement, or to any governmental entity for
any compensation or benefits (including, without limitation, vacation and
holiday remuneration, healthcare coverage or insurance, life insurance, pension
or profit-sharing benefits and disability benefits), payroll-related taxes or
withholdings, or any governmental charges or benefits (including without
limitation unemployment and disability insurance contributions or benefits and
workmen's compensation contributions or benefits) that may imposed upon or be
related to the performance by WCI and any of its employees, agents, contractors,
telemarketers, or other personnel used by WCI to discharge its obligations under
this Agreement, all of which shall be the sole responsibility of WCI, even if it
is subsequently determined by any court, the IRS or any other governmental
agency that such individual may be a common law employee of APOTHECON or any of
its Affiliates. All such matters of compensation, benefits and other terms of
employment for any employee, agent, contractor, telemarketer, or other personnel
used by WCI shall be solely a matter between WCI and such individual(s) or
entities.

                  WCI will indemnify, defend, and hold harmless each APOTHECON
Party from and against any damages, liability, loss and costs that may be paid
or payable by any such APOTHECON Party resulting from or in connection with any
claim or other cause of action asserted by:

                           (i)      any employees, agents, contractors,
         telemarketers, or other personnel of WCI used by it to perform its
         obligations under this Agreement, or

                           (ii)     by any third party (including federal, state
         or local governmental authorities) with respect to:

                           (iii)    any payment or obligation to make a payment
         to any employees, agents, contractors, telemarketers, or other
         personnel used by WCI to perform its obligations under this Agreement
         with respect to any compensation, benefits of any type under any
         employee benefit plan (as such term is defined above), and any other
         bonus, stock option, stock purchase, incentive, deferred compensation,
         supplemental retirement, severance and other similar fringe or employee
         benefit plans, programs or arrangements that may be sponsored at any
         time by APOTHECON or any of its Affiliates or by WCI or any of its
         Affiliates, even if it is subsequently determined by any court, the IRS
         or any other governmental agency that any such employee, agent,
         contractor, telemarketer, and other person used by WCI to discharge its
         obligations hereunder may be a common law employee of APOTHECON or any
         of its Affiliates; and

                                      -16-
<PAGE>
 
                           (iv)     the payment or withholding of any
         contributions, payroll taxes, or any other payroll-related item by or
         on behalf of WCI or any of its employees, agents, contractors,
         telemarketers, and other personnel with respect to which APOTHECON, WCI
         or any of WCI's employees, agents, contractors, telemarketers, and
         other personnel may be responsible hereunder or pursuant to applicable
         law to pay, make, collect, withhold or contribute, even if it is
         subsequently determined by any court, the IRS or by any other
         governmental agency that any such employee, agent, contractor,
         telemarketer, and other person used by WCI to discharge its obligations
         hereunder may be a common law employee of APOTHECON or any of its
         Affiliates.

Nothing contained in this Section 13(d) is intended to or will effect or limit
any compensation payable by APOTHECON to WCI for the services rendered by WCI
pursuant to this Agreement.

                  (e) WCI shall maintain for the entire term of this Agreement
comprehensive general liability and product liability coverage of no less than
[REDACTED] per occurrence. Apothecon, Inc. and Bristol-Myers Squibb Company
shall be named as insureds on the policy. WCI shall furnish to APOTHECON
evidence of such insurance, upon request.

                  (f) The indemnification obligations set forth in this Section
13 shall survive termination of the Agreement.

                  14. Confidentiality.

                  (a) Each party acknowledges that it may receive confidential
or proprietary information of the other party in the performance of this
Agreement. Each party shall hold confidential and shall not, directly or
indirectly, disclose, publish or use for the benefit of any third party or
itself, except in carrying out its duties hereunder, any confidential or
proprietary information of the other party, without first having obtained the
furnishing party's written consent to such disclosure or use. "Confidential or
proprietary information" shall include, inter alia, know-how, scientific
information, clinical data, efficacy and safety data, adverse event information,
formulas, methods and processes, specifications, pricing information (including
discounts, rebates and other price adjustments) and other terms and conditions
of sales, customer information, business plans, and all other intellectual
property. This restriction shall not apply to any information within the
following categories:

                           (i)      information that is known to the receiving
         party or its Affiliates prior to the time of disclosure to it, to the
         extent evidenced by written records or other competent proof;

                           (ii)     information that is independently developed
         by employees, agents, or independent contractors of the receiving party
         or its Affiliates without reference to or reliance upon the information
         furnished by the disclosing party, as evidenced by written records or
         other competent proof;

                           (iii)    information disclosed to the receiving party
         or its Affiliates by a third party that has a right to make such
         disclosure;

                                      -17-
<PAGE>
 
                           (iv)     information that is contained in any written
         promotional material prepared by APOTHECON for use in connection with
         the Products; or

                           (v)      any other information that becomes part of
         the public domain through no fault or negligence of the receiving
         party.

                  The receiving party shall also be entitled to disclose the
other party's Confidential Information that is required to be disclosed in
compliance with applicable laws or regulations (including, without limitation,
to comply with SEC, NASDAQ or stock exchange disclosure requirements), or by
order of any governmental body or a court of competent jurisdiction; provided
that the party required to disclose such information shall use all reasonable
efforts to obtain confidential treatment of such information by the agency or
court.

                  (b) This obligation shall survive the termination or
expiration of this Agreement for [REDACTED] years.

                  (c) The confidentiality obligations described above shall be
in addition to the parties' obligations under the Confidential Disclosure
Agreement dated as of July 14, 1998, except that to the extent there is an
conflict between that agreement and provisions of this Agreement, this Agreement
shall govern.

                  15. Right of First Negotiation

                  If, during the Copromotion Term for either of the Products,
APOTHECON determines that it is interested in entering into an arrangement with
an unAffiliated Person (hereinafter "Third Party") to sell or out-license the
right to sell either of the Products or the right to either of the Trademarks
(any such rights being hereafter referred to as a "Right"), then, provided the
Copromotion Term for the product or trademark to be sold or out-licensed is
still in effect, APOTHECON shall give WCI a right of first negotiation to
acquire such Right as follows:

                  (a) APOTHECON shall give written notice to WCI of its interest
in selling or out-licensing the Right. WCI shall have [REDACTED] days after
receipt of such notice to decide whether or not it wishes to pursue negotiations
for such an arrangement with respect to such Right and to submit a proposal to
APOTHECON. In the event that WCI declines to pursue negotiations or does not
reply to APOTHECON's notice within the [REDACTED] day period, APOTHECON shall be
free to negotiate and enter into an arrangement with respect to such Right with
a Third Party.

                  (b) In the event that WCI expresses interest in negotiations
and submits a preliminary proposal, then for an additional [REDACTED] day
period, APOTHECON shall conduct negotiations on an exclusive basis with WCI
diligently and in good faith to reach an arrangement with WCI. At the end of
such [REDACTED] day period, if the parties have not reached an agreement at such
time, WCI shall give APOTHECON a written notice setting forth the final offer by
WCI for such an arrangement (the Final Offer). If APOTHECON rejects the Final
Offer, it shall thereafter be free to negotiate and enter into an arrangement
with respect to such Right with a Third Party as provided in section 15(c).

                                      -18-
<PAGE>
 
                  (c) In the event the parties fail to negotiate a written
agreement pursuant to Sections 15(b) above within the period provided therein,
APOTHECON shall be free to enter into an arrangement for the selling or
out-licensing of the Right with a Third Party; provided, however, that for a
period of twelve months from the expiration of the [REDACTED] exclusive
negotiation period set forth in section 15(b) APOTHECON shall not enter into an
arrangement with a Third Party with respect to such Right on terms less
favorable to APOTHECON than the Final Offer without first reoffering to WCI the
opportunity to enter into an arrangement on the terms set forth in the Final
Offer. In the event of such a reoffer, WCI shall have [REDACTED] days to advise
APOTHECON of its interest in entering into an arrangement on such terms. In the
event that WCI expresses interest in such an arrangement on such terms, the
parties shall conduct exclusive negotiations and conclude an agreement
incorporating such terms within [REDACTED] days thereafter. For purposes of this
Section 15(c), WCI acknowledges and agrees that APOTHECON shall have the right,
in its sole discretion, to determine whether an offer from a Third Party that
consists in whole or in part of non-cash compensation is more or less favorable
to APOTHECON than the Final Offer.

                  16. Representations and Warranties.

                  (a) APOTHECON represents and warrants to WCI that (i) the
execution, delivery and performance of this Agreement by APOTHECON does not
conflict with, or constitute a breach of or under, any order, judgment,
agreement or instrument to which APOTHECON is a party; (ii) the execution,
delivery and performance of this Agreement by APOTHECON does not require the
consent of any person or the authorization of (by notice or otherwise) any
governmental or regulatory authority; (iii) the rights granted by APOTHECON to
WCI hereunder do not conflict with any rights granted by APOTHECON to any third
party; and (iv) APOTHECON or BMS owns the Trademarks and NDAs for the Products.

                  (b) WCI represents and warrants to BMS that (i) the execution,
delivery and performance of this Agreement by WCI does not conflict with, or
constitute a breach of or under, any order, judgment, agreement or instrument to
which WCI is a party; and (ii) the execution, delivery and performance of this
Agreement by WCI does not require the consent of any person or the authorization
of (by notice or otherwise) any governmental or regulatory authority.

                  17. Notices. Unless otherwise explicitly set forth herein, any
notice required or permitted to be given hereunder shall be in writing and shall
be delivered personally by hand, or sent by reputable overnight courier,
signature required, to the addresses of each party set forth below or to such
other address or addresses as shall be designated in writing in the same matter:

                  (a) If to APOTHECON:

                  APOTHECON, INC.
                  777 Scudders Mill Road
                  Plainsboro, NJ  08536
                  Attention:  General Manager

with a copy to the attention of the "Vice President and Senior Counsel" at the
same address.

                                      -19-
<PAGE>
 
                  (b) If to WCI:

                  Warner Chilcott Inc.
                  Rockaway 80 Corporate Center
                  100 Enterprise Drive
                  Suite 280
                  Rockaway, N.J. 07866
                  Attention: President

with a copy to "General Counsel" at the same address.

All notices shall be deemed given when received by the addressee.

                  18. Miscellaneous Provisions.

                  (a) Assignment. Neither party shall assign or otherwise
transfer this Agreement or any interest herein or right hereunder without the
prior written consent of the other party, and any such purported assignment,
transfer or attempt to assign or transfer any interest herein or right hereunder
shall be void and of no effect; except that (i) APOTHECON may sell or
out-license any Right pursuant to Section 15 of this Agreement and (ii) each
party (x) may assign its rights and obligations hereunder to an Affiliate
without the prior consent of the other party (although, in such event, the
assigning party shall remain responsible for all of its obligations and
agreements set forth herein, notwithstanding such assignment) and (y) may assign
its rights and obligations to a successor (whether by merger, consolidation,
reorganization or other similar event) or purchaser of all or substantially all
of its business assets relating to the Products, provided, that such successor
or purchaser has agreed in writing to assume all of such party's rights and
obligations hereunder and a copy of such assumption is provided to the other
party hereunder, and provided further that nothing in this Section 18(a) shall
preclude APOHTECON from exercising its right to terminate the Copromotion Term
under Section 12 (b) or (c).

                  (b) Non-Waiver. Any failure on the part of a party to enforce
at any time or for any period of time any of the provisions of this Agreement
shall not be deemed or construed to be a waiver of such provisions or of any
right of such party thereafter to enforce each and every such provision on any
succeeding occasion or breach thereof.

                  (c) Dispute Resolution. If any dispute arises under this
Agreement which cannot be resolved expeditiously by the NMT after due
consideration, the matter shall be submitted to the President of WCI and the
General Manager of APOTHECON for resolution. Any dispute that can not be so
resolved within 30 days after submission shall be submitted for arbitration in
accordance with the rules of the American Arbitration Association, and the award
or decision made by the arbitrator(s) designated pursuant to the American
Arbitration Association rules of arbitration shall be binding upon the parties
hereto and a judgment consistent therewith may be entered in any court of
competent jurisdiction; provided, however, that nothing herein contained shall
preclude a party from seeking equitable remedies in any court of competent
jurisdiction. Any such arbitration proceedings shall be conducted in New Jersey.

                                      -20-
<PAGE>
 
                  (d) Entirety of Agreement. This Agreement contains the entire
understanding of the parties with respect to the subject matter hereof and
supersedes all previous and contemporaneous verbal and written agreements,
representations and warranties with respect to such subject matter. This
Agreement (or any provision or term hereof) may be released, waived, changed or
supplemented only by a written agreement signed by an officer or other
authorized representative of the party against whom enforcement of any release,
waiver, change or supplement is sought. This Agreement shall not be strictly
construed against either party hereto.

                  (e) Public Announcements. The form and content of any public
announcement to be made by one party regarding this Agreement, or the subject
matter contained herein, shall be subject to the prior written consent of the
other party (which consent may not be unreasonably withheld), except as may be
required by applicable law (including, without limitation, disclosure
requirements of the SEC, NASDAQ, or any other stock exchange) in which event the
other party shall endeavor to give the other party reasonable advance notice and
review of any such disclosure. Proposed public announcements submitted to the
other party for approval shall be considered approved if the submitting party
has not received comments or objections from the other party within fifteen (15)
days from the date of submission, provided that public announcements proposed by
WCI must be simultaneously provided to both the General Manager and in house
Legal Counsel for APOTHECON, at Apothecon, Inc., 777 Scudders Mill Road,
Plainsboro, New Jersey.

                  (f) Governing Law. This Agreement shall be governed by and
construed in accordance with the internal laws of the State of New Jersey,
without regard to its conflicts of law principles.

                  (g) Relationship of the Parties. In making and performing this
Agreement, the parties are acting, and intend to be treated, as independent
entities and nothing contained in this Agreement shall be construed or implied
to create an agency, partnership, joint venture, or employer and employee
relationship between APOTHECON and WCI. Except as otherwise provided herein,
neither party may make any representation, warranty or commitment, whether
express or implied, on behalf of or incur any charges or expenses for or in the
name of the other party. No party shall be liable for the act of any other party
unless such act is expressly authorized in writing by both parties hereto.

                  (h) Counterparts. This Agreement shall become binding when any
one or more counterparts hereof, individually or taken together, shall bear the
signatures of each of the parties hereto. This Agreement may be executed in any
number of counterparts, each of which shall be deemed an original as against the
party whose signature appears thereon, but all of which taken together shall
constitute but one and the same instrument.

                  (i) Force Majeure. Neither party shall be liable to the other
party for any failure to perform as required by this Agreement if the failure to
perform is due to circumstances reasonably beyond such party's control,
including, without limitation, acts of God, civil disorders or commotions, acts
of aggression, fire, explosions, floods, drought, war, sabotage, embargo,
unexpected safety or efficacy results obtained with either of the Products,
utility failures, material shortages, labor disturbances, a national health
emergency, or appropriations of property. A party 

                                      -21-
<PAGE>
 
whose performance is affected by a force majeure event shall take prompt action
using its reasonable best efforts to remedy the effects of the force majeure
event.

                                      -22-
<PAGE>
 
                  IN WITNESS WHEREOF, the parties hereto have duly executed this
Agreement as of the day and year first above written.

Apothecon, INC.                                 Warner Chilcott Inc.

By:  /s/ Richard J. Lane                        By: /s/ Roger M. Boissonneault  
     -----------------------------------            ----------------------------
     Richard J. Lane                                Roger M. Boissonneault
     Title: President U.S.                          Title: President
                  Medicines Group and
                  Worldwide Franchise Management





Prepared by Harvey C. Kaish,
McCarter & English, LLP

                                      -23-
<PAGE>
 
                                   Schedule A


                         Ovcon(R) & Estrace(R) Co-Promotion
                           Ovcon(R) 35 Payment Schedule



                  The following sets forth the performance based payment
schedule under which Apothecon will pay WCI for co-promoting Ovcon(R)35 in the
United States.

                  (i)     For the quarter ended March 31, 1999, [REDACTED] of
the excess, if any, of Net Sales for Ovcon(R)35 from [REDACTED] to [REDACTED]
and [REDACTED] of the excess, if any over [REDACTED].

                  (ii)    For the quarter ended June 30, 1999, [REDACTED] of the
excess, if any, of Net Sales for Ovcon(R)35 from [REDACTED] to [REDACTED] and
[REDACTED] of the excess, if any, over [REDACTED].

                  (iii)   For the quarter ended September 30, 1999, [REDACTED]
of the excess, if any, of Net Sales of Ovcon(R)35 from [REDACTED] to [REDACTED]
and [REDACTED] of the excess, if any, over [REDACTED].

                  (iv)    For the year ended December 31, 1999, [REDACTED] of
the excess, if any, of Net Sales for Ovcon(R)35 for the year ended December 31,
1999 from [REDACTED to [REDACTED] and [REDACTED] of the excess, if any, over
[REDACTED], minus the total of Performance Fees paid to WCI in respect of
Ovcon(R)35 for the first three calendar quarters of 1999. If the amount
calculated in accordance with the foregoing is a negative number, WCI shall pay
to Apothecon such amount.

                  (v)     For each calendar quarter beginning with the first
quarter of 2000 through the fourth quarter of 2003, [REDACTED] of the excess, if
any, of Net Sales of Ovcon(R)35 from [REDACTED] to [REDACTED] and [REDACTED] of
the excess, if any, over [REDACTED].

                                      -24-
<PAGE>
 
                                   Schedule B


                         Ovcon(R) & Estrace(R) Co-Promotion
                         Estrace Cream Payment Schedule



                  The following sets forth the performance based payment
schedule under which Apothecon will pay WCI for co-promoting Estrace(R) cream in
the United States.

                  (i)     For the quarter ended March 31, 1999, [REDACTED] of
the excess, if any, of Net Sales for Estrace(R) cream from [REDACTED] to
[REDACTED] and [REDACTED] of the excess, if any over [REDACTED].

                  (ii)    For the quarter ended June 30, 1999, [REDACTED] of the
excess, if any, of Net Sales for Estrace(R) cream from [REDACTED] to [REDACTED]
and [REDACTED] of the excess if any, over [REDACTED].

                  (iii)   For the quarter ended September 30, 1999, [REDACTED]
of the excess, if any, of Net Sales of Estrace(R) cream from [REDACTED] to
[REDACTED] and [REDACTED] of the excess, if any, over [REDACTED].

                  (iv)    For the year ended December 31, 1999, [REDACTED] of
the excess, if any, of the Net Sales for Estrace(R) Cream for the year ended
December 31, 1999 from [REDACTED] to [REDACTED] and [REDACTED] of the excess, if
any, over [REDACTED] minus the total of Performance Fees paid to WCI in respect
of Estrace(R) cream for the first three calendar quarters of 1999. If the amount
calculated in accordance with the foregoing is a negative number, WCI shall pay
to Apothecon such amount.

                  (v)     For each calendar quarter beginning with the first
quarter of 2000 through the fourth quarter of 2003, [REDACTED] of the excess, if
any, of Net Sales of Estrace(R) cream from [REDACTED] to [REDACTED] and
[REDACTED] of the excess, if any, over [REDACTED].

                                      -25-
<PAGE>
 
                                   Schedule C


                         Ovcon(R) & Estrace(R) Co-Promotion
                            Base Prescription Levels

<TABLE> 
<CAPTION> 
                                                     Total Prescriptions
Quarter Ending                      Year                      Ovcon(R)35                Estrace(R) Cream
<S>                                 <C>              <C>                              <C>     
March 31st                          2000                        [REDACTED]                     [REDACTED]

June 30th                           2000                        [REDACTED]                     [REDACTED]

September 30th                      2000                        [REDACTED]                     [REDACTED]

December 31st                       2000                        [REDACTED]                     [REDACTED]

March 31st                          2001                        [REDACTED]                     [REDACTED]

June 30th                           2001                        [REDACTED]                     [REDACTED]

September 30th                      2001                        [REDACTED]                     [REDACTED]

December 31st                       2001                        [REDACTED]                     [REDACTED]

March 31st                          2002                        [REDACTED]                     [REDACTED]

June 30th                           2002                        [REDACTED]                     [REDACTED]

September 30th                      2002                        [REDACTED]                     [REDACTED]

December 31st                       2002                        [REDACTED]                     [REDACTED]

March 31st                          2003                        [REDACTED]                     [REDACTED]

June 30th                           2003                        [REDACTED]                     [REDACTED]

September 30th                      2003                        [REDACTED]                     [REDACTED]

December 31st                       2003                        [REDACTED]                     [REDACTED]
</TABLE> 

                                      -26-