EX-10.1



 Exhibit 10.1 
  





 
 Exhibit 10.1 
AMENDMENT OF
SOLICITATION/MODIFICATION OF CONTRACT 
1. CONTRACT ID CODE

PAGE OF PAGES 
1 1 
2. AMENDMENT/MODIFICATION NO. 0018 
3. EFFECTIVE DATE 
See Block 16C 
4. REQUISITION/PURCHASE REQ. NO. 
N/A 
5. PROJECT NO. (If applicable) 
6. ISSUED BY CODE 
ASPR-BARDA 
7. ADMINISTERED BY (If other than Item 6) 
CODE 
ASPR-BARDA01 
ASPR-BARDA 
330 INDEPENDENCE AVE SW 
ROOM 644-G 
WASHINGTON DC 20201 
ASPR-BARDA 
330 INDEPENDENCE AVE SW RM G644 
WASHINGTON DC 20201 
8. NAME AND ADDRESS OF CONTRACTOR (No., street, county, State and ZIP Code) 
BIOCRYST
PHARMACEUTICALS, INC. 
4505 EMPEROR BOULEVARD, SUITE 200 
DURHAM, NC 27703

(X) 
9A. AMENDMENT OF SOLICITATION NO. 
9B. DATED (SEE ITEM 11) 
X 
10A. MODIFICATION OF CONTRACT/ORDER NO. 
HHSO100200700032C 
10B. DATED (SEE ITEM 13) 
01/03/2007 
CODE 
FACILITY CODE 
11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS 
The above numbered solicitation is
amended as set forth in Item 14. The hour and date specified for receipt of Offers is extended, is not extended. Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the
following methods: (a) By completing items 8 and 15, and returning copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or telegram which includes a
reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this
amendment your desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and date
specified. 
12. ACCOUNTING AND APPROPRIATION DATA (If required) 
N/A

13. THIS ITEM ONLY APPLIES TO MODIFICATION OF CONTRACTS/ORDERS. 
IT MODIFIES
THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14. 
CHECK ONE A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE
IN THE CONTRACT ORDER NO. 
IN ITEM 10A. 
B. THE ABOVE NUMBERED CONTRACT/ORDER
IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation 
date, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF
FAR 43.103(b). 
X 
C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO
AUTHORITY OF: 
BILATERAL MODIFICATION AT THE MUTUAL AGREEMENT OF THE PARTIES

D. OTHER (Specify type of modification and authority) 
E. IMPORTANT:
Contractor is not, X is required to sign this document and return 1 copies to the issuing office. 
14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF
section headings, including solicitation/contract subject matter where feasible.) 
This Contract’s expiration date is changed by 30 days from March 31,
2014 to April 30, 2014. 
Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains
unchanged and in full force and effect. 
15A. NAME AND TITLE OF SIGNER (Type or print) 
16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print) 
KEVIN NILLES 
15B. CONTRACTOR/OFFEROR 
15C. DATE SIGNED 
16B. UNITED STATES OF AMERICA 
16C. DATE SIGNED 
(Signature of person authorized to sign) 
(Signature of Contracting Officer) 
NSN 7540-01-152-8070 
Previous edition unusable 
STANDARD FORM 30 (REV. 10-83) 
Prescribed by GSA FAR (48 CFR) 53.243