U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Animal Biosciences & Biotechnology Laboratory: Beltsville, MD
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Announcements
                        ABBL Journal Club
                    USDA Civil Rights Policy StatementSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BARC) Beltsville Agricultural Research Center Animal Biosciences & Biotechnology Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            GADDE, UJVALA DEEPTHI - US Department Of Agriculture (USDA)item
                                            RATHINAM, T - University Of Arkansasitem
                                            Lillehoj, Hyun
  Submitted to: Animal Health Research Reviews
                                    Publication Type: Review Article
                                    Publication Acceptance Date: 11/16/2015
                                    Publication  Date: 12/1/2015
                                    Citation: Gadde, U., Rathinam, T., Lillehoj, H.S. 2015. Passive immunization with hyperimmune egg yolk IgY as prophylaxis and therapy for poultry diseases-A review. Animal Health Research Reviews. 16(2):163-176. doi: 10.1017/S1466252315000195.Interpretive Summary: Understanding the role of various immune factors which are secreted by specific immune cells (T lymphocytes) in the host are critical to develop prevention strategies against many infectious agents.  In this study, ARS scientists collaborated with scientists in a Korean university to study the role of one specific immune factor called IL-17 which is secreted by T lymphocytes in a bacterial infection using the duck as a model.  The results showed that the IL-17 protein enhances the innate immune reponse in ducks but not in chickens by inducing other bioactive proteins in immune cells that cause inflammation.  This study showed an underlying immune mechanism which is important in host’s response to a bacterial infection in duck species. This paper also points out animal species-differences in host immune response to pathogens.
                                Technical Abstract: Passive immunization with pathogen-specific egg yolk antibodies (IgY) is emerging as a potential alternative to antibiotics for the treatment and prevention of various human and animal diseases.  Laying hens are an excellent source of high-quality polyclonal antibodies, which can be collected noninvasively from egg yolks.  The use of IgY offers several advantages in that it is environmental friendly, nontoxic, and reduces the numbers of animals required for antibody production.  This article reviews the use of IgY antibodies in the treatment and prevention of enteric pathogen infections in poultry.  Brief descriptions of the production, structure, and properties of IgY are also presented. Some limitations of the technology and future perspectives are discussed.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov