**EXHIBIT      4.1 (c)**

**AGREEMENT      AND AMENDMENT NO. 2 OF THE DISTRIBUTION AGREEMENT DATED FEBRUARY 25,      2004**

| **Between :**       | -                EDAP TMS S.A., a French *société                anonyme*having                its registered office at Parc d'activité La Poudrette Lamartine, 4-6, rue                du Dauphiné , 69120 Vaulx-en-Velin, France (“**EDAP                TMS”**)                                                                                               |
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|                     | -                EDAP S.A., a French *société                anonyme*having                its registered office at 4-6, rue du Dauphiné , 69120 Vaulx-en-Velin,                France (“**EDAP**”)                                                                                                                                                                   |
|                     |                                                                                                                                                                                                                                                                                                                                                                                             |
|                     | -                Technomed Medical Systems S.A., a French *société                anonyme*having                its registered office at 4-6, rue du Dauphiné , 69120 Vaulx-en-Velin,                France (“**Technomed**”) (collectively,                the “**EDAP                Parties**”)On                the one hand,                    |
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| **And                :** | HT                Prostate Therapy Management Company L.L.C., a limited liability company                incorporated under the laws of Delaware (United States), having                its registered office at 1841 West Oak Parkway,                Suite A, Marietta, GA 30062, United                States (“**HT                Prostate**”)On                the other hand, |

**WHEREAS,      **
*inter      alia*

**WHEREAS,      **
*bons      de souscription d’actions*
**Warrants**

|   | - | 100,000                warrants of category D, which may be exercised as from January 1,                2006 if                HT Prostate Therapy Management                Company L.L.C. or any other Healthtronics Company purchases from                EDAP TMS                or its subsidiaries, at least four (4) lithotripters in                2005 (“**Warrants                D**”);  |
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|   | - | 100,000                warrants                of category E,                which may be exercised as from January 1, 2007 if HT Prostate Therapy                Management                Company L.L.C. or any other Healthtronics Company purchases from                EDAP TMS                or its subsidiaries, at least four (4) lithotripters in                2006 (“**Warrants                E**”); |
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|   | - | 100,000                warrants                of category F, which                may be exercised as from January 1, 2008 if HT Prostate Therapy                Management                Company L.L.C. or any other Healthtronics Company purchases from                EDAP TMS                or its subsidiaries, at least four (4) lithotripters in 2007                (“**Warrants                F**”). |
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**WHEREAS**
*given      the fact that HT Prostate wishes to focus its efforts on obtaining the PMA      for      Ablatherm and on developing the HIFU market potential on the US territory,      and      does not want to pursue the distribution of EDAP's lithotriptors in the US,      the      Parties wish to amend the terms and conditions of Warrants D, Warrants E and      Warrants F as follows:*

**Article      1**

**Article      2**

**Article      3**

*Warrants      D may be exercised as from January 1, 2006 if, in 2005, HT Prostate Therapy      *
*Management      Company L.L.C. or any other Healthtronics Company (i) purchases from EDAP TMS      or      its subsidiaries at least two (2) lithotripters, and (ii) places an irrevocable      order to EDAP TMS or its subsidiaries for the purchase of one (1) Ablatherm      at a      net price equal to USD 490,000*

**Article      4**

*procès-verbaux*

**Article      5**

| 5.1 | As                a result of the foregoing provisions, and subject to the                decision by the board of directors of EDAP TMS to adopt the amendment                set                forth in Article 3 above, the                Parties hereby agree to amend the Distribution Agreement as follows,                which                amendment shall become effective upon adoption of the amendment referred                to in Article 3 above: |
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*The      Warrant Exercise Milestone relating to the Warrants of category D, as set forth      in the resolution of the Board of Directors dated January 28, 2005, as per      Exhibit A, is amended as reflected in a new resolution of the Board of Directors      of the Parent Corporation set forth as Exhibit E. In addition, HT Prostate      has      waived any and all rights it may have under the 100,000 Category E Warrants      and      the 100,000 Category F Warrants that it holds, which have become null and void      and may no longer be exercised, as is also reflected in a resolution of the      Board of Directors of the Parent Corporation set forth in Exhibit      E.*

| 5.2 | Except                as amended in Article 5.1 above, all of the provisions of the Distribution                Agreement remain in full force and                effect. |
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**IN      WITNESS WHEREOF, **

| EDAP                TMS S.A.  S/                HUGUES DE BANTEL                By:                Hugues de BantelTitle:                *Directeur                Général*  | EDAP                S.A.  S/                HUGUES DE BANTEL                By:                Hugues de BantelTitle:                *Président                - Directeur Général*  |
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| TECHNOMED                MEDICAL SYSTEMS S.A.  S/                HUGUES DE BANTEL                By:                Hugues de BantelTitle:*Président - Directeur Général*    | HT                PROSTATE THERAPY MANAGEMENT LLC  S/                CHRISTOPHER SCHNEIDER                By:                Christopher Schneider Title:                President, Medical Devices |