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Title:   Author  item
                                            LINDSAY  DAVID S  - COL VET MED, AUBURN UNIVitem
                                            RIPPEY  N S  - COL VET MED, AUBURN UNIVitem
                                            POWE  T A  - COL VET MED, AUBURN UNIVitem
                                            SARTIN  E A  - COL VET MED, AUBURN UNIVitem
                                            Dubey, Jitenderitem
                                            BLAGBURN  B L  - COL VET MED, AUBURN UNIV
  Submitted to: Veterinary Record
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 3/31/1995
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary: Neospora caninum is a recently discovered single celled parasite of livestock and companion animals.  It causes abortion in cattle, sheep, goats, and horses.  Its life cycle and source of infection are unknown. There is no vaccine to control this infection.  Scientists at the Beltsville Agricultural Research Center and Auburn University describe an  experimental pygmy goat model for neosporosis induced abortion.  They observed lesions and parasites in aborted goat fetuses.  This model will be of use by scientists to test candidate vaccines for neosporosis.
                                Technical Abstract: Seven pregnant pygmy goats (1 control and 6 inoculated) were used.  The control goat remained normal throughout the study and delivered 2 healthy kids.  Abortion, fetal deaths, and stillbirths were observed in some pregnant goats inoculated with N. caninum.  Two pregnant pygmy goats inoculated with N. caninum early in gestation (day 51 of gestation) had  fetuses that died and were aborted, or died and were reaborbed.  Neospora caninum tachyzoites and lesions were observed in the brains, spinal cords, and hearts of aborted fetuses; parasites were also isolated from the placenta.  Four additional pregnant pygmy goats (2 inoculated mid-gestation [day 85], 2 late gestation [day 127]) did not abort after inoculation.  However, 1 goat inoculated during mid-gestation delivered a stillborn fetus that had died about 1 week prior to parturition.  This goat kid was congenitally infected with N. caninum.  Neospora caninum was  isolated from the placentas of all inoculated goats examined.  Neonatal neosporosis was not observed in the liveborn goat kid.  Goats did not undergo abortion or have congenitally infected kids when they were rebred and evaluated for neosporosis.


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