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Title:   Author  item
                                            Richards, Gary
  Submitted to: Bacteriophage
                                    Publication Type: Literature Review
                                    Publication Acceptance Date: 10/7/2014
                                    Publication  Date: 12/1/2014
                                    Citation: Richards, G.P. 2014. Bacteriophage remediation of bacterial pathogens in aquaculture: a review of the technology. Bacteriophage. doi:10.4161/21597081.2014.975540.Interpretive Summary:
                                Technical Abstract: Bacteriophages have been proposed as an alternative to antibiotic usage and several studies on their application in aquaculture have been reported.  This review highlights progress to date on phage therapies for the following fish and shellfish diseases and associated pathogens: hemorrhagic septicemia (Aeromonas hydrophila) in loaches, furunculosis (Aeromonas salmonicida) in trout and salmon, edwardsiellosis (Edwardsiella tarda) in eel, columnaris disease (Flavobacterium columnare) in catfish, rainbow trout fry syndrome or cold water disease (Flavobacterium psychrophilum) in trout and salmon, lactococcosis (Lactococcus spp.) in yellowtail, ulcerative skin lesions (Pseudomonas aeruginosa) in freshwater catfish, bacterial hemorrhagic ascites disease (Pseudomonas plecoglossicida) in ayu fish, streptococcosis (Streptococcus iniae) in flounder, and luminescent vibriosis (Vibrio harveyi) in shrimp.  Information is reviewed on phage specificity, host resistance, routes of administration, and dosing of fish and shellfish.  Limitations in phage research are described and recommended guidelines are provided for conducting future phage studies involving fish and shellfish.


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