U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Obesity and Metabolism Research: Davis, CA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Laboratories
                        Bennett Group
                                    Huang Group
                                    Keim Group
                                    Laugero Group
                                    Newman GroupSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Pacific West Area Davis, California Western Human Nutrition Research Center Obesity and Metabolism Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            WIDAMAN, ADRIANNE - University Of Californiaitem
                                            STANHOPE, KIMBER - University Of Californiaitem
                                            CHEN, GUOXIA - University Of Californiaitem
                                            MEDICI, VALENTINA - University Of Californiaitem
                                            BREMER, ANDREW - University Of Californiaitem
                                            LEE, VIVIEN - University Of Californiaitem
                                            NUNEZ, MARINEWLLW - University Of Californiaitem
                                            HAVEL, PETER - University Of Californiaitem
                                            Keim, Nancy
  Submitted to: Meeting Abstract
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 11/9/2015
                                    Publication  Date: 4/2/2016
                                    Citation: Widaman, A.M., Stanhope, K.L., Chen, G.X., Medici, V., Bremer, A.A., Lee, V., Nunez, M.V., Havel, P.J., Keim, N.L. 2016. Comparison of the Effects of a Sweetened Beverage Intervention on Self-Selected Food Intake. Meeting Abstract. Experimental Biology 2016, April 2-6, 2016, San Diego, CA.Interpretive Summary:
                                Technical Abstract: Evidence suggests that the intake of added sugar increases the risk of chronic disease and should be targeted for reduction. It is unclear if all types of added sugar have equivalent effects on food intake. This prospective, blinded intervention study compared parallel groups consuming one of five types of beverage sweeteners: glucose (GLU), fructose (FRU), sucrose (SUC), high fructose corn syrup (HFCS) or aspartame (ASP). The beverages were provided at ~25% of estimated energy needs for weight maintenance for 2 weeks and consumed along with the subjects’ usual diets. Before (week 0) and at the end (week 2) of the intervention, subjects were admitted to a metabolic ward and as inpatients participated in a day-long protocol designed to measure ad libitum food and beverage intake from buffets offered at breakfast, lunch, and dinner. One hundred and thirty men and women with an average age of 26.3 ± 6.3 y and a BMI of 25.3 ± 3.6 kg/m2 participated. The changes in food and beverage energy intake (week 2 – week 0) were analyzed using ANCOVA, adjusting for BMI, sex, and energy intake at week 0. Energy intake was significantly affected by sugar (p=0.0026, ANCOVA), with subjects consuming SUC (386 ± 96 kcal, p=0.0011, Tukeys) or HFCS (242 ± 89 kcal, p=0.022, Tukeys) significantly increasing their intake at 2 weeks compared with subjects consuming ASP (-169 ± 100 kcal) and compared with their week 0 intake (p=0.0001 and p=0.0072, respectively). Buffet energy intake did not change significantly for the groups consuming GLU (p=0.198), FRU (p=0.064), or ASP (p=0.096) between weeks 0 and 2. Further analysis of the influence of sex on buffet intake showed that the increases in energy intake at week 2 were mainly attributable to men. Men consuming SUC (580 ± 137 kcal, p=0.0072, Tukeys) or HFCS (426 ± 123 kcal, p=0.047, Tukeys) significantly increased their energy intake at 2 weeks compared with men consuming ASP (-176 ± 143 kcal).  In contrast, for women, there were no differences among groups, or between week 0 and week 2 buffet energy intake, regardless of the sweetened beverage assigned. In conclusion, we found that compared with aspartame, the caloric sweeteners, HFCS and sucrose, commonly used to sweeten soft drinks and fruit drinks, increased total energy intake during a day-long buffet protocol offered in a controlled research setting. The effect of these sweeteners was more pronounced in men.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov