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ARS Home Southeast Area Stuttgart, Arkansas Harry K. Dupree Stuttgart National Aquaculture Research Cntr Research Publications at this Location





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Research Project: The Role of Mucosal Surfaces and Microflora in Immunity and Disease Prevention Location:
                                Harry K. Dupree Stuttgart National Aquaculture Research Cntr Title:   Author  item
                                            Farmer, Bradleyitem
                                            Beck, Benjaminitem
                                            MITCHELL, ANDREW - Retired ARS Employeeitem
                                            Rawles, Steven

                                                         - *Steve*item
                                            Straus, David

                                                         - *Dave*
  Submitted to: Aquaculture Research
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 1/11/2016
                                    Publication  Date: 3/1/2016
                                    Publication URL: http://handle.nal.usda.gov/10113/5878559Citation: Farmer, B.D., Beck, B.H., Mitchell, A.J., Rawles, S.D., Straus, D.L. 2016. Dietary copper effects survival of channel catfish challenged with Flavobacterium columnare. Aquaculture Research. 48(4):1751-1758. doi:10.1111/are.13012.Interpretive Summary: Columnaris disease is an important bacterial disease of channel catfish commercially grown in the US.  Copper sulfate (CuSO4) has also been shown to be both therapeutic and prophylactic as a water treatment for columnaris disease.  Copper is also an essential diet component in animal feeds and CuSO4 is the form that is typically included in the base diet.  This study was conducted to evaluate whether fish feed supplemented with CuSO4 at would affect resistance to columnaris disease.  The results indicate that fish fed the copper-supplemented diet for two weeks had a significant increase in resistance to columnaris disease.  This increase in resistance was also dose dependent and results indicated up to a 30% increase in survival after two weeks on the supplemented feed.  After 4 weeks on the copper-supplemented feed the increase in survival was less than at weeks but still greater than 10% higher survival than fish fed the base diet.  No statistical differences were found in growth rate or food conversion ratio.
                                Technical Abstract: Columnaris disease is one of the most important bacterial diseases of channel catfish, Ictalurus punctatus, commercially grown in the US.  Copper sulfate (CuSO4) has also been shown to be both therapeutic and prophylactic as a water treatment for columnaris disease.  As copper is an essential dietary component in animal feeds and CuSO4 is typically included in the base diet, a study was conducted to evaluate whether fish feed supplemented with CuSO4 at 0, 40, and 80 mg/kg of diet and fed at a daily rate of 3% body weight would affect resistance to columnaris disease.  The results indicate that fish fed the copper-supplemented diet for two weeks had a significant increase in resistance to columnaris disease.  This increase in resistance was also dose dependent.  The mean percent survival (+/- SEM) for fish fed the base diet (un-supplemented) for two weeks and then challenged was 2.0% +/- 1.1.  Fish fed the base plus 40 mg CuSO4/kg had a mean survival of 22.0% +/- 11.0.  Fish fed the base plus 80 mg CuSO4/kg had a mean survival of 29.3% +/- 13.4.  The mean percent survival for fish fed the base diet for four weeks and then challenged was 28.3 % +/- 9.0.  Fish fed the base plus 40 mg CuSO4/kg for four weeks had a mean survival of 12.5 % +/- 6.3.  Fish fed the base plus 80 mg CuSO4/kg for four weeks had a mean survival of 40.5 % +/- 8.1.  No statistical differences were found in growth rate or food conversion ratio.


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