Exhibit31.1

CERTIFICTION OF PRINCPAL EXECUTIVE OFFICER

IMarlene Krauss, M.D., Chief Executive Officer, certifythat:

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| 1.  | I have reviewed this Quarterly Report onForm 10-QSB of KBL Healthcare Acquisition Corp.II; |

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| 2.  | Based on my knowledge, this quarterly reportdoes not contain any untrue statement of a material fact or omit tostate a material fact necessary to make the statements made, in lightof the circumstances under which such statements were made, notmisleading with respect to the period covered by thisreport; |

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| 3.  | Based on my knowledge, the financialstatements, and other financial information included in this report,fairly present in all material respects the financial conditions,results of operations and cash flows of the small business issuer asof, and for, the periods presented in thisreport. |

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| 4.  | The small business issuer’s othercertifying officer(s) and I are responsible for establishing andmaintaining disclosure controls and procedures (as defined in ExchangeAct Rules 13a-15(e) and 15d-15(e)) and internal control over financialreporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f))for the small business issuer andhave: |

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|  | a)  | Designed such disclosure controls andprocedures, or caused such disclosure controls and procedures to bedesigned under our supervision, to ensure that material informationrelating to the small business issuer, including its consolidatedsubsidiaries, is made known to us by others within those entities,particularly during the period in which this report is beingprepared; |

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|  | b)  | Designed such internal control overfinancial reporting, or caused such internal control over financialreporting to be designed under our supervision, to provide reasonableassurance regarding the reliability of financial reporting and thepreparation of financial statements for external purposes in accordancewith generally accepted accountingprinciples |

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|  | c)  | Evaluated the effectiveness of thesmall business issuer’s disclosure controls and procedures andpresented in this report our conclusions about the effectiveness of thedisclosure controls and procedures, as of the end of the period coveredby this report based on such evaluation;and |

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|  | d)  | Disclosed in this report any change in thesmall business issuer’s internal control over financialreporting that occurred during the small business issuer’s mostrecent fiscal quarter (the small business issuer’s fourth fiscalquarter in the case of an annual report) that has materially affected,or is reasonably likely to materially affect, the small businessissuer’s internal control over financial reporting;and |

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| 5.  | The small business issuer’s othercertifying officer(s) and I have disclosed, based on our most recentevaluation of internal control over financial reporting, to the smallbusiness issuer’s auditors and the audit committee of the smallbusiness issuer’s board of directors (or persons performing theequivalent functions): |

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|  | a)  | All significantdeficiencies and material weaknesses in the design or operation ofinternal control over financial reporting which are reasonably likelyto adversely affect the small business issuer's ability torecord, process, summarize and report financial information;and |

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|  | b)  | Any fraud, whether or not material, thatinvolves management or other employees who have a significant role inthe small business issuer's internal control over financialreporting. |

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| /s/Marlene Krauss, M.D.                                                                                                                                         |  | Dated: May  15,2006 |
|      Marlene Krauss,M.D.     Chief ExecutiveOfficer     (Principal ExecutiveOfficer) |  |                |
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