U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Animal Biosciences & Biotechnology Laboratory: Beltsville, MD
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Announcements
                        ABBL Journal Club
                    USDA Civil Rights Policy StatementSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BARC) Beltsville Agricultural Research Center Animal Biosciences & Biotechnology Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            KIM, JI EUN - US Department Of Agriculture (USDA)item
                                            Lillehoj, Hyunitem
                                            HONG, YEONG HO - Chung-Ang Universityitem
                                            KIM, GEUN BAE - Chung-Ang Universityitem
                                            LEE, SUNG HYEN - Rural Development Administration - Koreaitem
                                            LILLEHOJ, ERIK - University Of Marylanditem
                                            BRAVO, DAVID - Pancosma Sa
  Submitted to: Research in Veterinary Science
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 7/28/2015
                                    Publication  Date: 8/2/2015
                                    Publication URL: http://handle.nal.usda.gov/10113/61647Citation: Kim, J., Lillehoj, H.S., Hong, Y., Kim, G., Lee, S., Lillehoj, E.P., Bravo, D.M. 2015. Dietary Capsicum and Curcuma longa oleoresins alter  the intestinal microbiome and Necrotic Enteritis  Severity in three commercial broiler breeds. Research in Veterinary Science. 102:150-158.Interpretive Summary: Avian necrotic enteritis (NE) is an intestinal disease caused by the bacterium, Clostridium perfringens and represents one of the most economically important infectious diseases affecting the world’s poultry industry.  With increasing regulatory and voluntary restrictions on the use of antibiotics in poultry, there is an enhanced interest in developing alternatives to antibiotics.  Modulation of innate immunity using natural foods and herbal-derived essential oils offers another avenue to enhance poultry health and reduce the negative effects of pathogen infection.  ARS scientists in collaboration with university scientists and industry partners, investigated using plant-derived feed additives, oils from peppers and turmeric, to stimulate the chicken immune system and to enhance host defense against intestinal bacteria and parasites.  Furthermore, this study showed that these dietary herbal-derived essential oils also alterd the distribution and number of the types of bacteria in the gut resulting in a reduction of the negative effects caused by the NE disease.  This is the first study to show a significant effect of herbal-derived essential oils on NE and associated with intestinal microbes.  This opens a new way to reduce the use of antibiotics in poultry disease control.
                                Technical Abstract: Three commercial broiler breeds were fed from hatch with a diet supplemented with Capsicum and Curcuma longa oleoresins, and co-infected with Eimeria maxima and Clostridium perfringens to induce necrotic enteritis (NE).  Pyrotag deep sequencing of bacterial 16S rRNA showed that gut microbiota compositions were quite distinct depend on the broiler breed type. In the absence of oleoresin diet, the number of operational taxonomic units (OTUs), was decreased in infected Cobb, and increased in Ross and Hubbard, compared with the uninfected.  In the absence of oleoresin diet, all chicken breeds had decreased Candidatus Arthromitus, while the proportion of Lactobacillus was increased in Cobb, but decreased in Hubbard and Ross.  Oleoresin supplementation of infected chickens  increased OTUs in Cobb and Ross, but decreased OTUs in Hubbard, compared with  unsupplemented/infected controls.  Oleoresin supplementation of infected Cobb and Hubbard was associated with an increased percentage of gut Lactobacillus and decreased Selenihalanaerobacter, while Ross had a decreased fraction of Lactobacillus and increased Selenihalanaerobacter, Clostridium, Calothrix, and Geitlerinema.  These results suggest that dietary Capsicum/Curcuma oleoresins reduced the negative consequences of NE on body weight and intestinal lesion, in part, through alteration of the gut microbiome in 3 commercial broiler breeds.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov