U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Animal Biosciences & Biotechnology Laboratory: Beltsville, MD
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Announcements
                        ABBL Journal Club
                    USDA Civil Rights Policy StatementSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BARC) Beltsville Agricultural Research Center Animal Biosciences & Biotechnology Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Lillehoj, Hyunitem
                                            KIM, JI EUN - US Department Of Agriculture (USDA)
  Submitted to: American Society of Microbiologists Abstracts
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 2/5/2015
                                    Publication  Date: N/A
                                    Publication URL: https://handle.nal.usda.gov/10113/61045Citation: N/AInterpretive Summary:
                                Technical Abstract: Necrotic enteritis (NE) is among the most economically important enteric diseases affecting the poultry industry worldwide.  In an effort to develop alternatives to antibiotics strategies to reduce the negative impact of NE to gut health, we investigated the efficacy of dietary phytonutrient mixture, Capsicum and Curcuma oleoresins on disease susceptibility to NE caused by co-infections with Eimeria maxima and Clostridium perfringens, and the role of gut microbiota community in three commercial broiler chicken breeds, Cobb, Ross and Hubbard.  Dietary Capsicum and Curcuma oleoresins significantly improved body weights and reduced the gut lesions in all three breeds compared with their respective control groups (P<0.05).  The results of pyrotag deep sequencing of the bacterial 16S rRNA gene showed that bacterial profiles in the ileum were quite distinct depend on the broiler breed type.  Interestingly, Candidatus Arthromitus, one of segmented filamentous bacteria (SFB) involved in regulatingT cells on the mucosa surface, was commonly identified as a key gut microbe in untreated and uninfected (control group), untreated and infected (NE group) and treated and infected (NE + XT group) in Cobb and Hubbard broilers, and a Ross control group in, indicating a potential immune regulatory role of Candidatus Arthromitus in the ileum of three broiler breeds.  These new findings increase our understanding of the positive effect of dietary phytonutrients as alternatives to antibiotics and the possible role of gut microbiota in local immune regulation in broiler chickens.  This study is the first to report the effects of dietary phytonutrients on the differential immune modulatory role of gut microbiota in commercial broiler breeds and opens a new way to reduce the use of antibiotics in poultry disease control.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov