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Title:   Author  item
                                            Meinhardt, Lyndelitem
                                            Bailey, Bryan
  Submitted to: Book Chapter
                                    Publication Type: Book / Chapter
                                    Publication Acceptance Date: 1/15/2016
                                    Publication  Date: 2/22/2016
                                    Citation: Meinhardt, L.W., Bailey, B.A. 2016. Moniliophthora roreri Genome and Transcriptome. In: Bailey, B.A., Meinhardt, L.W., editors. Cacao diseases: A history of old enemies and new encounters, Switzerland: Springer. p. 97-135.Interpretive Summary:
                                Technical Abstract: Frosty pod rot disease of cacao is one of the most destructive diseases of cacao and at this time is limited to regions in South America and Central America. Frosty pod rot is caused by a fungal pathogen Moniliophthora roreri, a basidiomycete that is closely related to another cacao pathogen that causes the Witches’ Broom disease, Moniliophthora perniciosa.  Combined these two pathogens are the leading causes of cacao yield losses in the Americas. Both pathogens are unique in that they have long biotrophic phases after infection as the disease progresses.  In this chapter genomic and transcriptomic sequencing will be used to corroborate and hypothesize various mechanisms of the molecular interactions of the host and pathogen during the disease interaction of frosty pod rot. The systematic timing of fungal and plant gene regulation in this pathosystem appears to be a key component of this plant disease resulting in specific molecular and cellular interactions. When this coordinated gene regulation is disrupted, for example in a resistant plant variety, the disease interaction fails.


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