4




                                             November 15, 2000



Mr. Richard T. Kelecy
Chief Financial Officer
Perma-Fix Environmental Services, Inc.
1940 NW 67th Place, Suite A
Gainesville, FL 32653


Dear Dick,

Reference  is  made  to  that  certain  Loan  and   Security
Agreement  dated  January 25, 1998  (as  amended,  restated,
supplemented  or otherwise modified from time to  time,  the
"Loan  Agreement")  among Perma-Fix Environmental  Services,
Inc.  and its direct and indirect subsidiaries named on  the
signature  pages hereof, jointly and severally  ("Perma-Fix"
or "Borrower") and Congress Financial Corporation (Florida),
("Congress"  or "Lender").  Capitalized terms used  but  not
otherwise defined herein shall have the meanings ascribed to
them in the Loan Agreement.

Borrower  has  advised  Lender  that  as  a  result  of  the
acquisition of Diversified Scientific Services, Inc.  (DSSI)
and  related  recording  of purchase  accounting,  effective
August  31,  2000,  Borrower is not in compliance  with  the
financial  covenant set forth in section 9.14  of  the  Loan
Agreement, which states:

     "Borrowers shall, at all times, maintain  Adjusted
     Net  Worth  on a consolidated basis in respect  of
     Borrowers of not less than $3,000,0000."

As  a  consequence of this Event of Default, we are entitled
to  exercise  various  rights and remedies  under  the  Loan
Agreement.  Borrower has requested that the Lender agree  to
amend  section  9.14 of the Loan Agreement effective  August
31, 2000 as follows:

     Borrowers shall, (i) at all times, maintain  net
     worth  in accordance with GAAP on a consolidated
     basis  of  not less than $19,500,000;  and  (ii)
     starting on December 31, 2001 Adjusted Net Worth
     of   not  less  than  $3,0000,000  through   the
     Expiration Date.

Borrowers hereby represent, warrant, acknowledge and  affirm
that no other Event of Default or any default which with the
passage  of  time,  the  giving of notice,  or  both,  would
constitute  an  Event  of  Default  has  occurred   and   is
continuing.
<PAGE>
Borrowers  shall pay to Lender an amendment fee of  $15,000,
which fee shall be due and payable, and deemed to have  been
fully  earned,  on  the  date  of  this  Amendment  and   an
additional monthly fee of $3,000 starting October 31st, 2000
and continuing for each month that the Adjusted Net Worth is
less than $3,000,000.

Except  as  amended herein, all the terms and conditions  of
the  Loan  Agreement between us remain  in  full  force  and
effect.

The foregoing is a one-time accommodation and is only to the
extent  specifically set forth herein.   This  accommodation
shall not be construed as an obligation on our part to waive
or consent to any departure from any obligation you have, or
any  right,  power, or remedy under our documents  with  you
which  we  would  otherwise have, on  any  future  occasion,
whether similar in kind, or otherwise.

Please  acknowledge  your acceptance of  this  amendment  by
signing below and return this letter to the undersigned.

Sincerely,

CONGRESS FINANCIAL CORPORATION
     (FLORIDA)

______________________________
Gary Dixon
Vice President
                     AGREED:

                         BORROWERS:
                         PERMA-FIX ENVIRONMENTAL SERVICES,
                         INC., a Delaware corporation

                         By:
                             ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         INDUSTRIAL WASTE MANAGEMENT, INC.,
                         a Missouri corporation

                         By:
                            ________________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                                 2
<PAGE>
                         SCHREIBER, YONLEY & ASSOCIATES
                         (formerly known as Schreiber, Grana
                         & Yonley, Inc.), a Missouri
                         corporation

                         By:
                            ________________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX TREATMENT SERVICES,
                         INC., an Oklahoma corporation

                         By:
                            ________________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX, INC., an Oklahoma
                         corporation

                         By:
                            _______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         MINTECH, INC., an Oklahoma
                         corporation

                         By:
                            _______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         RECLAMATION SYSTEMS, INC., an
                         Oklahoma corporation

                         By:
                           ________________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX OF NEW MEXICO, INC.,
                         a New Mexico corporation

                         By:
                            ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX OF FLORIDA, INC.,
                         a Florida corporation

                         By:
                            _____________________________
                              Richard T. Kelecy, Chief
                              Financial Officer


                                3
<PAGE>

                         PERMA-FIX OF MEMPHIS, INC.,
                         a Tennessee corporation

                         By:
                           _____________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX OF DAYTON, INC.,
                         an Ohio corporation

                         By:
                            _____________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX OF FORT LAUDERDALE, INC.,
                         a Florida corporation

                         By:
                            ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         PERMA-FIX OF MICHIGAN, INC., a
                         Michigan corporation

                         By:
                            ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         CHEMICAL CONSERVATION OF
                         GEORGIA, INC., a Georgia
                         corporation

                         By:
                            ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         CHEMICAL CONSERVATION
                         CORPORATION, INC., a Florida
                         corporation

                         By:
                            ______________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                         DIVERSIFIED SCIENTIFIC SERVICES, INC.,
                         a Tennessee corporation

                         By:
                            ________________________________
                              Richard T. Kelecy, Chief
                              Financial Officer

                                4