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Title:   Author  item
                                            SINGH, CHINGAKHAM - University Of Mississippiitem
                                            CHANU, SAIKHOM - University Of Mississippiitem
                                            KH, LENIN - University Of Mississippiitem
                                            SWAPANA, NINGOMBAM - University Of Mississippiitem
                                            Cantrell, Charlesitem
                                            ROSS, SAMIR - University Of Mississippi
  Submitted to: Journal of Pharmacognosy and Phytochemistry
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 8/30/2014
                                    Publication  Date: 10/21/2014
                                    Citation: Singh, C.B., Chanu, S.B., Kh, L., Swapana, N., Cantrell, C.L., Ross, S.A. 2014. Chemical composition and biological activity of the essential oil of rhizome of Zingiber zerumbet (L.) smith. Journal of Pharmacognosy and Phytochemistry. 3(3):130-133.Interpretive Summary: Zingiber zerumbet (L.) Smith is a monocotyledonous perennial medicinal plant belonging to the Zingiberaceae family. It is known as shampoo ginger or pinecone ginger as its rhizomes produce foaming properties likes that of shampoo.  The aim was designed to study the biological activity and chemical composition of essential oil of Zingiber zerumbet.  The essential oil extracted from the rhizome of the plant was analysed by gas chromatography-mass spectroscopy  and its major components amounting  to 98.4 %  were found to be zerumbone (75.2%), alpha-caryophyllene (7.1%), camphene (5.1%), eucalyptol (2.4%), and camphor (3.0%). The essential oil and zerumbone exhibited antimalarial and antileishmanial activities whereas only Cryptococcus neoformans showed antimicrobial activity on the essential oil.
                                Technical Abstract: Technical Abstract:  The aim was designed to study the biological activity and chemical composition of essential oil of Zingiber  zerumbet (L.) Smith. The essential oil extracted from the rhizome of the plant was analysed by gas chromatography-mass spectroscopy  and its major components amounting  to 98.4 %  were found to be zerumbone (75.2%), a- caryophyllene (7.1%), camphene (5.1%), eucalyptol (2.4%), and camphor (3.0%). Antioxidant activity and total phenol content assay were studied using the DPPH and Folin-Ciocalteu colorimetric methods. Antimalarial, anti-leishmanial, antimicrobial assays were analysed for the essential oil and its major component, zerumbone. The essential oil and zerumbone exhibited antimalarial and antileishmanial activities whereas only Cryptococcus neoformans showed antimicrobial activity on the essential oil.


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