<PAGE>   1
                                                                     Exhibit 4.3

                                                                  EXECUTION COPY






                             PAINE WEBBER GROUP INC.


                                       to


                 CHASE MANHATTAN BANK USA, NATIONAL ASSOCIATION


                                 ---------------

                          Subordinated Debt Securities

                                 ---------------

                          Fourth Supplemental Indenture

                                 ---------------



                          Dated as of November 3, 2000


                           Supplementing the Indenture
                           Dated as of March 15, 1988

                                 ---------------
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                                    FOURTH SUPPLEMENTAL INDENTURE dated as of
                           November 3, 2000, among PAINE WEBBER GROUP INC., a
                           corporation duly organized and existing under the
                           laws of Delaware (herein called the "Company"),
                           having its principal office at 1285 Avenue of the
                           Americas, New York, New York 10019, UBS AMERICAS
                           INC., a corporation duly organized and existing under
                           the laws of Delaware (herein called "UBS Americas"),
                           having its principal office at 677 Washington
                           Boulevard, Stamford, Connecticut 06901, and CHASE
                           MANHATTAN BANK USA, NATIONAL ASSOCIATION, a
                           corporation duly organized and existing under the
                           laws of the State of Delaware (formerly known as
                           Chemical Bank (Delaware)), as Trustee (herein called
                           the "Trustee").


                                    RECITALS

                  The Company and the Trustee are parties to an Indenture dated
as of March 15, 1988, as supplemented by the First Supplemental Indenture dated
as of September 22, 1989, the Second Supplemental Indenture dated as of March
22, 1991 and the Third Supplemental Indenture dated as of November 30, 1993 (as
so supplemented, the "Indenture"), relating to the issuance from time to time by
the Company of its Securities. Capitalized terms used, and not otherwise
defined, herein shall have the same meanings given them in the Indenture.

                  The Company, UBS AG, an Aktiengesellschaft organized under the
laws of Switzerland, and UBS Americas (then known as Neptune Merger Subsidiary,
Inc.), a wholly owned subsidiary of UBS AG have entered into an Agreement and
Plan of Merger, dated as of July 12, 2000 (the "Merger Agreement"). Pursuant to
the Merger Agreement, the Company will merge with and into UBS Americas, with
UBS Americas as the surviving corporation (the "Merger"), the Merger to be
effective upon the filing, in the office of the Secretary of State of the State
of Delaware, of a certificate of merger the ("Effective Time").

                  The Company has requested the Trustee to join with it in the
execution and delivery of this fourth supplemental indenture (this "Fourth
Supplemental Indenture") in order to supplement and amend the Indenture, by
amending and adding certain provisions thereof, pursuant to which UBS Americas
will expressly assume the due and punctual payment of the principal of (and
premium, if any) and interest on
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all Securities and the performance of every covenant of the Indenture on the
part of the Company to be performed or observed (the "Assumption"), as set forth
in Section 801(1) of the Indenture.

                  Section 801 of the Indenture provides that the Assumption must
be effected through a supplemental indenture, executed and delivered to the
Trustee, in form satisfactory to the Trustee.

                  Section 901 of the Indenture provides that a supplemental
indenture may be entered into by the Company and the Trustee, without the
consent of any Holders, to evidence the succession of another corporation to the
Company and assumption by any such successor of the covenants of the Company
contained in the Indenture and in the Securities.

                  At the request of the Trustee, the Company (a) has furnished
the Trustee with (1) an Officers' Certificate complying with the requirements of
Sections 102 and 801(4) of the Indenture, stating, among other things, that the
Merger and this Fourth Supplemental Indenture comply with Article Eight of the
Indenture and that all conditions precedent provided for in the Indenture
relating to the Merger and this Fourth Supplemental Indenture have been complied
with and (2) an Opinion of Counsel complying with the requirements of Sections
102, 801(4) and 903 of the Indenture and (b) has delivered to the Trustee a
Board Resolution as required by Section 901 of the Indenture authorizing the
execution by the Company of this Fourth Supplemental Indenture and its delivery
by the Company to the Trustee.

                  At the request of the Trustee, UBS Americas (a) has furnished
the Trustee with (1) an opinion of counsel and (2) a Secretary's Certificate and
(b) has delivered to the Trustee a Board Resolution authorizing the execution by
UBS Americas of this Fourth Supplemental Indenture and its delivery by UBS
Americas to the Trustee.

                  All things necessary to make this Fourth Supplemental
Indenture a valid agreement of the Company, UBS Americas and the Trustee, in
accordance with the terms of the Indenture, and a valid amendment of and
supplement to the Indenture have been done.

                  NOW, THEREFORE, THIS FOURTH SUPPLEMENTAL INDENTURE WITNESSETH:

                  For and in consideration of the premises and the purchase of
the Securities by the Holders thereof, it is mutually agreed, for the equal and
proportionate benefit of all Holders of the Securities or of series thereof, as
follows:
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I.       AMENDMENTS TO THE INDENTURE

                  A. Assumption and Substitution. UBS Americas hereby assumes,
as of the Effective Time, the due and punctual payment of the principal of (and
premium, if any) and interest on all the Securities and the performance of every
covenant of the Indenture on the part of the Company to be performed or
observed. UBS Americas hereby succeeds to, and is substituted for, the Company
in the Indenture, as of the Effective Time.

II.      NOTICES

                  A. For purposes of Section 105(2) of the Indenture, the
address of UBS Americas is: 677 Washington Boulevard, Stamford, Connecticut
06901, Attention: Secretary.

                  B. UBS Americas hereby agrees to give the Trustee prompt
notice of the Effective Time.

III.     NOTATION ON SECURITIES

                  A. All Securities authenticated and delivered after the
Effective Time shall bear the following notation, which may be stamped or
imprinted thereon:

                           "In connection with the merger of Paine Webber Group
                  Inc. (the "Company") into UBS Americas Inc. and pursuant to
                  the Fourth Supplemental Indenture dated as of November 3,
                  2000, UBS Americas Inc. has assumed the due and punctual
                  payment of the principal of (and premium, if any) and interest
                  on this Security and the performance of every covenant of the
                  Indenture on the part of the Company to be performed or
                  observed."

                  UBS Americas shall arrange for and pay all expenses related to
such notation.

IV.      GENERAL PROVISIONS

                  A. The recitals contained herein shall be taken as the
statements of the Company and UBS Americas, and the Trustee assumes no
responsibility for the correctness of same. The Trustee makes no representation
as to the validity of this Fourth Supplemental Indenture. The Indenture, as
supplemented and amended by this Fourth Supplemental Indenture, is in all
respects hereby adopted, ratified and confirmed.

                  B. The Trustee hereby accepts this Fourth Supplemental
Indenture and agrees to perform the same under the terms and conditions set
forth in the Indenture.
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                  C. This instrument may be executed in any number of
counterparts, each of which so executed shall be deemed to be an original, but
all such counterparts shall together constitute but one and the same instrument.

                  D. This Fourth Supplemental Indenture shall be governed by and
construed in accordance with the laws of the State of New York.
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                  IN WITNESS WHEREOF, the parties hereto have caused this Third
Supplemental Indenture to be duly executed, and their corporate seals to be
hereunto affixed and attested, all as of the day and year first above written.

                                       PAINE WEBBER GROUP INC.,

                                            by  /s/ Authorized Officer
                                               ---------------------------------
[SEAL]                                         Title: Senior Vice President

Attest:


 /s/
---------------------------

                                       UBS AMERICAS INC.,

                                            by  /s/  Louis Eber
                                               ---------------------------------
                                               Title: Executive Director


[SEAL]                                      by  /s/  Sandra Ward Costin
                                               ---------------------------------
                                               Title: Director


Attest:




                                       THE CHASE MANHATTAN BANK, as Trustee,

                                            by  /s/ Authorized Officer
                                               ---------------------------------
                                               Title: Vice President
---------------------------


[SEAL]

Attest: