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ARS Home Southeast Area Athens, Georgia U.S. National Poultry Research Center Exotic & Emerging Avian Viral Diseases Research Research Publications at this Location





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Title:   Author  item
                                            PEDERSEN, JANICE - Animal And Plant Health Inspection Service (APHIS)item
                                            Kapczynski, Darrellitem
                                            Suarez, Daviditem
                                            HINES, N.L. - Animal And Plant Health Inspection Service (APHIS)item
                                            KILLIAN, M.L. - Animal And Plant Health Inspection Service (APHIS)item
                                            SCHMITT, BEVERLY - Animal And Plant Health Inspection Service (APHIS)
  Submitted to: International Symposium on Avian Influenza
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 6/15/2012
                                    Publication  Date: 8/4/2012
                                    Citation: Pedersen, J.C., Kapczynski, D.R., Suarez, D.L., Hines, N., Killian, M., Schmitt, B.J. 2012. Serological examination of sera from hyperimmunized chickens and turkeys [abstract]. International Symposium on Avian Influenza. CDROM.Interpretive Summary:
                                Technical Abstract: Detection of avian influenza (AI) H5 and H7 antibody in commercial poultry is a World Organization for Animal Health (OIE) notifiable event and impacts trade.  Chickens and turkeys which had been vaccinated with an oil-emulsion H1N1/H3N2 influenza autogenous vaccine were inoculated with inactivated pandemic H1N1 (pH1N1) virus (chickens) and live pH1N1 virus (turkeys) to determine if multiple exposures to pH1N1 virus can result in non-specific hemagglutination-inhibition (HI) reactions against H5 AI.  Sera from the hyperimmunized chickens and turkeys and field vaccinated turkeys were tested to evaluate the possibility of cross-reaction to subtypes H1, H2, and H5 AI which genetically fall into a distinct phylogenetic clade.  Sera from field turkeys and hyperimmunized chickens and turkeys did result in a small number of positive H5 reactions, but the results do not appear to support cross-reactivity based on a clade-based relationship.


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