U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Vanraden, Paul
  Submitted to: Interbull Annual Meeting Proceedings
                                    Publication Type: Proceedings
                                    Publication Acceptance Date: 2/2/2012
                                    Publication  Date: 2/2/2012
                                    Citation: Van Raden, P.M. 2012. Avoiding bias from genomic pre-selection in converting daughter information across countries. Interbull Annual Meeting Proceedings. Interbull Bull. 45, 5 pp.Interpretive Summary: Breeders have exchanged and converted genetic evaluations of bulls across countries for decades, but traditional evaluations may become biased by pre-selection on genotype. Bulls that were pre-selected on genotype now have daughter records, and new methods are needed to include both foreign and genomic information in 1-step or multi-step evaluations. This study compared U.S. Jersey traditional evaluations (EBV), genomic evaluations (GEBV), daughter yield deviations (DYD) and genomic DYD (DYDg). Correlations between the 1-step and multi-step method GEBV for young U.S. bulls were fairly high (0.962) as compared to the correlations between GEBV and parent averages (0.853 to 0.869). Correlations between DYDg and DYD were very high for U.S. bulls (>0.9993) regardless of the inclusion of foreign or genomic information.  These results indicate that DYDg can account for pre-selection of bulls, and exchanging DYDg across countries could eliminate the need to partition genomic from phenotypic information when used in across country evaluations which will help increase accuracy of evaluations that aid breeders in identifying superior animals.
                                Technical Abstract: Methods to include both foreign and genomic information in single-step or multi-step evaluations were developed and compared using the U.S. national Jersey database. Breeders have exchanged and converted genetic evaluations of bulls across countries for decades, but traditional evaluations may become biased by pre-selection on genotype. When foreign and genomic data were added to the equations, daughter yield deviations computed from only domestic daughter records were very stable. Those could be exchanged internationally, thereby avoiding the difficulty of deregressing genomic evaluations. A final step in the multi-step method simply inserted the genomic evaluations and held them constant during iteration instead of adjusting the data vector and equations. For genotyped young bulls, multi-step evaluations were correlated by .962 to single-step evaluations computed with an algorithm that did not require inverting the genomic relationship matrix. Accuracy was similar but regressions were closer to expectation for the single-step evaluations.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov