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ARS Home Pacific West Area Davis, California Western Human Nutrition Research Center Obesity and Metabolism Research Research Publications at this Location





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Title:   Author  item
                                            VAN OMMEN, B - Tno Quality Of Lifeitem
                                            EL-SOHEMY, A - University Of Torontoitem
                                            HESKETH, JOHN - Newcastle Universityitem
                                            KAPUT, JIM - Food And Drug Administration(FDA)item
                                            FENECH, MICHAEL - Newcastle Universityitem
                                            EVELO, T - Commonwealth Scientific And Industrial Research Organisation (CSIRO)item
                                            MCARDLE, HARRY - Rowett Research Instituteitem
                                            BOUWMAN, JILDAU - Tno Quality Of Lifeitem
                                            LIETZ, GEORGE - Newcastle Universityitem
                                            MATHERS, JOHN - Newcastle Universityitem
                                            FAIRWEATHER-TAIT, SUE - University Of East Angliaitem
                                            VAN KRANEN, HENK - National Institute For Public Health And The Environment (RIVM)item
                                            ELLIOTT, RUAN - Institute Of Food Research - United Kingdomitem
                                            WOPEREIS, SUZAN - Tno Quality Of Lifeitem
                                            FERGUSON, LYNNETTE - University Of Aucklanditem
                                            MEPLAN, CATHERINE - Newcastle Universityitem
                                            PEROZZI, GIUDITTA - National Research Institute For Food And Nutrition (INRAN)item
                                            Allen, Lindsay

                                                         - *A*
  Submitted to: Genes and Nutrition
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 10/13/2010
                                    Publication  Date: 10/30/2010
                                    Citation: Van Ommen, B., El-Sohemy, A., Hesketh, J., Kaput, J., Fenech, M., Evelo, T., Mcardle, H.J., Bouwman, J., Lietz, G., Mathers, J.C., Fairweather-Tait, S., Van Kranen, H., Elliott, R., Wopereis, S., Ferguson, L.R., Meplan, C., Perozzi, G., Allen, L.H. 2010. The micronutrient genomics project: a community-driven knowledge base for micronutrient research. . 5(4):285-296.Interpretive Summary:
                                Technical Abstract: Micronutrients influence multiple metabolic pathways including oxidative and inflammatory processes. Optimum micronutrient supply is important for the maintenance of homeostasis in metabolism and, ultimately, for maintaining good health. With advances in systems biology and genomics technologies, it is becoming feasible to assess the activity of single and multiple micronutrients in their complete biological context. Existing research collects fragments of information, which are not stored systematically and are thus not optimally disseminated. The Micronutrient Genomics Project (MGP) was established as a community-driven project to facilitate the development of systematic capture, storage, management, analyses, and dissemination of data and knowledge generated by biological studies focused on micronutrient-genome interactions. Specifically, the MGP creates a public portal and open-source bioinformatics toolbox for all "omics" information and evaluation of micronutrient and health studies. The core of the project focuses on access to, and visualization of, genetic/genomic, transcriptomic, proteomic and metabolomic information related to micronutrients. For each micronutrient, an expert group is or will be established combining the various relevant areas (including genetics, nutrition, biochemistry, and epidemiology). Each expert group will (1) collect all available knowledge, (2) collaborate with bioinformatics teams towards constructing the pathways and biological networks, and (3) publish their findings on a regular basis. The project is coordinated in a transparent manner, regular meetings are organized and dissemination is arranged through tools, a toolbox web portal, a communications website and dedicated publications.


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