U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            DIKMEN, S - Uludag Universityitem
                                            Cole, Johnitem
                                            Null, Danielitem
                                            HANSEN, P - University Of Florida
  Submitted to: Journal of Dairy Science
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 3/5/2012
                                    Publication  Date: 6/28/2012
                                    Citation: Dikmen, S., Cole, J.B., Null, D.J., Hansen, P.J. 2012. Genomic evaluation of rectal temperature in Holstein cattle. Journal of Dairy Science. 95(Suppl. 2):401(abstr. 327). 2012.Interpretive Summary:
                                Technical Abstract: Heat stress negatively impacts the production, fertility, and health of dairy cattle. Rectal temperature (RT) has unfavorable genetic correlations with production, longevity, economic merit, and somatic cell score in Holstein cows. The objectives of the current study were to perform a genome-wide association study (GWAS) for rectal temperature in dairy cows under heat stress conditions, and to determine if single nucleotide polymorphisms (SNP) are associated with genes related to heat stress. Rectal temperature was measured between 1500 and 1700 h in 5,590 lactating Holstein cows sired by 3,322 bulls during the summer in north central Florida. Rectal temperature averaged 38.8 ± 0.57 degrees C, and ranged from 37.0 to 41.6 degrees C. The model included fixed effects of parity; random effects of herd-year, animal, and permanent environment; and regressions on temperature-humidity index and test-day milk yield. The pedigree included 886 animals with Illumina BovineSNP50 BeadChip (Illumina, Inc., San Diego, CA) genotypes. After SNP edits for call rates < 0.90, minor allele frequencies < 0.05, and Mendelian conflicts, 30,0018 markers remained. Genotypes for nine animals were dropped due to low call rates. (Co)variance components and breeding values were calculated using the AIREMLF90 and BLUPF90 software packages from the University of Georgia (Athens). The GWAS was performed with a one-step procedure as implemented in the POSTGSF90 software. The heritability and repeatability of RT were 0.06 and 0.22, which is lower than recent estimates, possibly because most sires had only a few daughters with records and pedigree ties were limited. The 20 SNP with the largest solutions were examined to determine if they were located in or near genes that could account for heat stress effects. Five SNP were located in introns: C1H21orf59 on Bos taurus autosome (BTA) 1, INADL on BTA3, ZNF335 on BT13, VPS13 on BTA16, and FTO on BTA18. The third-ranked SNP was located in an exon of CCT6B on BTA12. These results will help  identify genes involved in physiological responses to heat stress. Additional phenotypes are needed to improve estimates SNP effects.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov