U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Animal Biosciences & Biotechnology Laboratory: Beltsville, MD
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Announcements
                        ABBL Journal Club
                    USDA Civil Rights Policy StatementSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BARC) Beltsville Agricultural Research Center Animal Biosciences & Biotechnology Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            SHIRLEY, M - Non ARS Employeeitem
                                            Lillehoj, Hyun
  Submitted to: Avian Pathology
                                    Publication Type: Review Article
                                    Publication Acceptance Date: 6/1/2012
                                    Publication  Date: 6/23/2012
                                    Citation: Shirley, M.W., Lillehoj, H.S. 2012. The long view: A selective review of 40 years of coccidiosis research. Avian Pathology. 41(2):111-121.Interpretive Summary: This invited review written by an ARS scientist in collaboration with a scientist from UK summarizes the 40 years of  immunology and vaccinology research in avian intestinal parasitic diseases to reflect on the progress made in scientific research in this field since 1970.  Specific scientific discoveries and major accomplishments in parasite biology, immunology, and pathogen and host genomes have been documented in this review that will help scientists in poultry disease research and poultry industry to gain better understanding on the progress in avian parasitic disease research.
                                Technical Abstract: This selective review of 40 years of coccidiosis research is one of a number being written on important diseases of poultry to celebrate the 40th anniversary of the birth of Avian Pathology, the journal of the World Veterinary Poultry Association, and is written for the non-specialist. Our intention is to provide a flavour of the field problems and intellectual challenges, with an emphasis in the areas of immunology and vaccinology, that drove research in the 1970’s and to reflect on research progress since. The 1970’s sit in the middle of the modern history of 80 years of research in to avian coccidia. The decade now looks (1) backwards to the pioneering work on coccidia and coccidiosis in the late 1920’s and early 1930’s by researchers who laid the foundations of much fundamental knowledge, including speciation, life cycles, pathogenicity, host-specificity, induction of protective immunity and control by vaccination and chemotherapy and (2) forwards to the modern era in which molecular approaches are being applied to many studies, including Eimeria genomes and genetics, immune mechanisms and protective antigens and host susceptibility with the real prospect that a new generation of innovative vaccines will emerge. In this short and very highly selective review, the reader will be referred to many of the substantive texts and references to primary data for more detailed information. This review is also mostly written from our personal perspectives so that we can best give insights in to how some of the scientific questions of the day were framed and addressed. We therefore apologize to very many colleagues and other coccidiologists whose names and work are either not described at all or only in passing. In particular, whilst the absolutely critical importance of chemotherapy to the control of coccidiosis is highlighted, less attention is given to this topic in our descriptions of scientific progress.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov