U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Livestock Issues Research: Lubbock, TX
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    NewsletterSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Plains Area Lubbock, Texas Cropping Systems Research Laboratory Livestock Issues Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            BUNTYN, JOE - Mississippi State Universityitem
                                            Carroll, Jeffery

                                                         - *Jeff Carroll*item
                                            SMITH, T - Mississippi State Universityitem
                                            FALKENBERG, SHOLLIE - Mississippi State Universityitem
                                            RIVERA, J - Mississippi State Universityitem
                                            Collier, Chaditem
                                            SCHMIDT, TY - Mississippi State University
  Submitted to: Journal of Animal Science Supplement
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 7/11/2010
                                    Publication  Date: 10/11/2010
                                    Citation: Buntyn, J., Carroll, J.A., Smith, T., Falkenberg, S., Rivera, J., Collier, C.T., Schmidt, T. 2010. Use of a lipopolysaccharide (LPS) challenge to evaluate the innate immune response of Angus heifers with genotypic differences in GeneSTAR markers for intramuscular fat deposition [abstract]. 2010 American Society of Animal Science Meeting, July 11-15, 2010, Denver, CO. Journal of Animal Science. 88(E-Supplement 2):590.Interpretive Summary:
                                Technical Abstract: The objective of this study was to evaluate the innate immune response of Angus heifers with genotypic differences in terms of the presence or absence of GeneSTAR markers for intramuscular fat deposition. Twenty-three pure-bred Angus heifers (223 ± 44 kg) were sorted into two treatment groups based GeneSTAR markers; LowSTAR = no GeneSTAR markers ( n=11), and HighSTAR = one or more GeneSTAR markers (n=12). To evaluate immune response, LPS was administered via IV at 0.25 micrograms/kg BW. Prior to challenge (24 hrs), indwelling jugular catheters and indwelling rectal thermometers were inserted. Blood samples were collected at 30-min intervals and rectal temperatures (RT) at 1-min intervals from -2 to 8 h relative the LPS challenge at Time 0. Serum was analyzed for concentrations of cortisol and pro-inflammatory cytokines. HighStar heifers displayed greater (P < 0.05) RT responses and serum concentrations of cortisol compared to LowStar heifers post-LPS. LowStar heifers also had greater (P < 0.05) concentrations of IFN-gamma post-LPS. No differences (P>0.05) were observed between HighStar and LowStar heifers for IL-6 concentrations; however, LowStar heifers had greater (P<0.05) sustained IL-6 responses. These results suggest that heifers lacking markers for intramuscular fat deposition have an altered immune response compared to High GeneStar heifers.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov