U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Livestock Issues Research: Lubbock, TX
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    NewsletterSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Plains Area Lubbock, Texas Cropping Systems Research Laboratory Livestock Issues Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            CHAU, GILDA - Texas A&M Agricultural Experiment Stationitem
                                            Collier, Chaditem
                                            WELSH, THOMAS - Texas A&M Universityitem
                                            Carroll, Jeffery

                                                         - *Jeff Carroll*item
                                            LAURENZ, JAMIE - Texas A&M University
  Submitted to: Food and Agricultural Immunology
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 5/1/2009
                                    Publication  Date: 11/24/2009
                                    Citation: Chau, G.P., Collier, C.T., Welsh, T.H., Carroll, J.A., Laurenz, J.C. 2009. Beta-1-3-glucan effect on sow antibody production and passive immunization of progeny. Food and Agricultural Immunology. 20(3):185-193.Interpretive Summary: Of particular importance to swine producers is an effective immune system in breeding stock and their young piglets. Beta-glucans are complex sugars that have been found to affect immunity. Two indicators of potential beta-glucan affects were analyzed here. Specifically, sows were vaccinated and the resulting antibody (IgA, IgG, and IgM) production was measured and the subsequent passive immunization of their piglets was analyzed. To test this hypothesis, the treatments included: 1) Corn-soy fed control group, 2) beta-glucan, 3) vaccination, and 4) beta-glucan + vaccination. Piglet birth and weaning weights were not affected by treatment. Independent of treatment, the antibodies in colostrum were elevated and declined rapidly. Vaccination resulted in an increase in specific IgG and IgA antibodies in sow colostrum and milk with a corresponding increase in pigs serum at 4 days of age. However, beta-glucan did not enhance specific antibodies in pig serum. While the dosage used here did not enhance passive immunization in pigs, beta-glucan can be potentially useful as an oral adative to improve immune responses to vaccination.
                                Technical Abstract: Beta-glucans are glucose homopolymers known to modulate immunity. Here, the beta-glucan effect on sow antibody production and passive immunization of neonatal pigs was analyzed. Treatments included: 1) Corn-soy fed control group, 2) beta-glucan, 3) App vaccination, and 4) beta-glucan + App vaccination. Birth and weaning weights were not affected (P>0.05) by treatment. Independent of treatment, IgA, IgG, and IgM in colostrum were elevated and declined rapidly. Vaccination against App resulted in an increase (P<0.05) in IgG and IgA specific for App serotypes 1, 5, and 7 in colostrum and milk and a corresponding increase (P<0.05) in serum in pigs at 4 d of age. However, beta-glucan did not enhance specific App antibodies in pig serum. While the dosage used here did not enhance passive immunization in pigs, beta-glucan can be potentially efficacious as an oral adjuvant to enhance immunoglobulin production in response to vaccination.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov