U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Obesity and Metabolism Research: Davis, CA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Laboratories
                        Bennett Group
                                    Huang Group
                                    Keim Group
                                    Laugero Group
                                    Newman GroupSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Pacific West Area Davis, California Western Human Nutrition Research Center Obesity and Metabolism Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            WITBRACHT, MEGAN - University Of Californiaitem
                                            Van Loan, Martaitem
                                            Adams, Seanitem
                                            Keim, Nancyitem
                                            Laugero, Kevin
  Submitted to: Journal of Nutrition
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 10/22/2012
                                    Publication  Date: 11/28/2012
                                    Citation: Witbracht, M., Van Loan, M.D., Adams, S.H., Keim, N.L., Laugero, K.D. 2012. Dairy food consumption and meal-induced cortisol response interact to influence weight loss in overweight women undergoing a 12-week meal-controlled weight loss intervention. Journal of Nutrition. 143(1):45-52.DOI: https://doi.org/10.3945/jn.112.166355                                                              
                                Interpretive Summary: Including dairy foods in the diet may facilitate diet-induced weight loss, possibly by modifying the metabolic effects of the hormone cortisol.  This study assessed in overweight women whether inclusion of dairy foods in an energy-restricted diet affects daily cortisol concentrations, and whether person-to-person differences in cortisol concentrations at baseline influence the magnitude of weight loss in response to the diet.  Women received either adequate dairy: 3-4 servings of dairy foods per day (AD) or low dairy: =1 serving per day (LD) in a 12-week moderate energy restricted dietary intervention.   We found that, on average across all women, energy restriction increased the daily minimum and decreased the daily range in cortisol concentrations from baseline to post-intervention.  Energy restriction also enhanced the cortisol response (rise) to eating dinner, but only in LD (this effect was not observed in women consuming adequate dairy).  Compared to LD, AD led to a greater loss in body weight and total and upper body fat, but only in women characterized at baseline as having a normal cortisol response to eating dinner (responders); weight and fat lost in AD and LD were similar in those women who did not display a cortisol response to eating dinner (non-responders).  Overall, our results suggest that dairy food consumption interacts with some underlying factors related to cortisol regulation to facilitate body weight and upper body fat loss.
                                Technical Abstract: Dairy foods enhance weight loss in animal models possibly by modifying the metabolic effects of cortisol.  This study aimed to determine in overweight women (ages 20-45; n=51) whether inclusion of dairy foods in an energy-restricted diet affects basal and stimulated cortisol concentrations, and whether baseline differences in provoked cortisol concentrations explain the magnitude of weight loss in response to the intervention.  Women received either adequate dairy: 3-4 servings of dairy foods per day (AD) or low dairy: =1 serving per day (LD) in a 12-week moderate energy restricted dietary intervention.   Participants were tested in a 12h lab visit, which included a standard breakfast and lunch, and an ad libitum dinner buffet.  Salivary cortisol was determined at 10 timepoints across the day from waking to bedtime.  Energy restriction increased (P=0.04) the minimum and decreased (P=0.02) the diurnal amplitude in cortisol concentrations from baseline to post-intervention.  The dinner-induced rise in cortisol was enhanced (P=0.02) by energy restriction, but only in LD.  Compared to LD, AD induced (P=0.04) greater reductions in body weight and total and upper body fat, but only in women characterized at baseline as having a dinner-induced cortisol response (responders); weight and fat lost in AD and LD were similar in non-responders.  Overall, energy restriction dampened diurnal cortisol fluctuations (symptomatic of hypothalamic pituitary adrenal (HPA) axis dysfunction) and enhanced dinner-induced cortisol concentrations.  However, AD prevented the latter.  Furthermore, certain phenotypic markers of HPA axis function may be important for revealing weight-reducing effects of consuming dairy foods.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov