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ARS Home Plains Area Fargo, North Dakota Edward T. Schafer Agricultural Research Center Cereal Crops Research Research Publications at this Location





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Title:   Author  item
                                            CAVANAGH, COLIN - Commonwealth Scientific And Industrial Research Organisation (CSIRO)item
                                            Chao, Shiaomanitem
                                            WANG, SHICHEN - Kansas State Universityitem
                                            HUANG, BEVAN - Commonwealth Scientific And Industrial Research Organisation (CSIRO)item
                                            STEPHAN, STUART - Commonwealth Scientific And Industrial Research Organisation (CSIRO)item
                                            KIANI, SEIFOLLAH - Kansas State Universityitem
                                            FORREST, KERRIE - Queensland Department Of Primary Industries & Fisheriesitem
                                            SAINTENAC, CYRILLE - Kansas State Universityitem
                                            Brown-Guedira, Ginaitem
                                            AKHUNOVA, ALINA - Kansas State Universityitem
                                            See, Devenitem
                                            Bai, Guihuaitem
                                            Pumphrey, Michaelitem
                                            TOMAR, LUXMI - Haryana Agricultural Universityitem
                                            WONG, DEBBIE - Department Of Primary Industriesitem
                                            KONG, STEPHAN - Department Of Primary Industriesitem
                                            REYNOLDS, MATTHEW - International Maize & Wheat Improvement Center (CIMMYT)item
                                            LOPEZ DA SILVA, MARTA - International Maize & Wheat Improvement Center (CIMMYT)item
                                            Bockelman, Harolditem
                                            TALBERT, LUTHER - Montana State Universityitem
                                            ANDERSON, JAMES - University Of Minnesotaitem
                                            DREISIGACKER, SUSANNE - International Maize & Wheat Improvement Center (CIMMYT)item
                                            BAENZIGER, STEPHEN - University Of Nebraskaitem
                                            CARTER, ARRON - Washington State Universityitem
                                            KORZUN, VIKTOR - Kws Saat Agitem
                                            MORRELL, PETER - University Of Minnesotaitem
                                            DUBCOVSKY, JORGE - University Of Californiaitem
                                            MORELL, MATTHEW - Commonwealth Scientific And Industrial Research Organisation (CSIRO)item
                                            SORRELLS, MARK - Cornell Universityitem
                                            HAYDEN, MATTHEW - Department Of Primary Industriesitem
                                            AKHUNOV, EDUARD - Kansas State University
  Submitted to: Proceedings of the National Academy of Sciences (PNAS)
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 3/25/2013
                                    Publication  Date: 5/14/2013
                                    Citation: Cavanagh, C., Chao, S., Wang, S., Huang, B.E., Stephan, S., Kiani, S., Forrest, K., Saintenac, C., Brown Guedira, G.L., Akhunova, A., See, D.R., Bai, G., Pumphrey, M.O., Tomar, L., Wong, D., Kong, S., Reynolds, M., Lopez Da Silva, M., Bockelman, H.E., Talbert, L., Anderson, J.A., Dreisigacker, S., Baenziger, S., Carter, A., Korzun, V., Morrell, P.L., Dubcovsky, J., Morell, M., Sorrells, M., Hayden, M., Akhunov, E. 2013. Genome-wide comparative diversity uncovers multiple targets of selection for improvement in hexaploid wheat landrace and cultivars. Proceedings of the National Academy of Sciences. 110:8057-8062.Interpretive Summary: Domesticated crops have experienced strong human-driven selection aimed at the development of improved varieties adapted to local conditions. To detect regions of the wheat genome subject to selection during improvement, we developed a high-throughput array to interrogate 9,000 gene-associated DNA markers based on single nucleotide differences, known as single nucleotide polymorphisms (SNPs), in a worldwide sample of 2,994 accessions of hexaploid wheat including landraces and modern cultivars. The genetic locations of 7500 of those SNPs on 21 wheat chromosomes were determined and were the basis for this study. The results from genetic diversity analyses showed that wheat improvement has mainly relied on preexisting variation in landraces, and the transition from landraces to cultivars has had little effect on diversity. The analyses further revealed that genetic variation present in cultivars was mainly explained by the geographic origin of breeding pools, and that chromosomal regions targeted by selection for wheat improvement have changed over time, potentially reflecting breeding efforts aimed at developing higher yielding varieties adapted to new or changing local conditions. The limited usage of exotic germplasm for wheat improvement as found in this study provides an important take home message in that breeders can broaden the genetic diversity by integrating landraces and wild relatives in their efforts on wheat improvement.
                                Technical Abstract: Domesticated crops have experienced strong human-driven selection aimed at the development of improved varieties adapted to local conditions. To detect regions of the wheat genome subject to selection during improvement, we developed a high-throughput array to interrogate 9,000 gene-associated DNA markers based on single nucleotide differences, known as single nucleotide polymorphisms (SNPs), in a worldwide sample of 2,994 accessions of hexaploid wheat including landraces and modern cultivars. The genetic locations of 7500 of those SNPs on 21 wheat chromosomes were determined and were the basis for this study. The results from genetic diversity analyses showed that wheat improvement has mainly relied on preexisting variation in landraces, and the transition from landraces to cultivars has had little effect on diversity. The analyses further revealed that genetic variation present in cultivars was mainly explained by the geographic origin of breeding pools, and that chromosomal regions targeted by selection for wheat improvement have changed over time, potentially reflecting breeding efforts aimed at developing higher yielding varieties adapted to new or changing local conditions. The limited usage of exotic germplasm for wheat improvement as found in this study provides an important take home message in that breeders can broaden the genetic diversity by integrating landraces and wild relatives in their efforts on wheat improvement.


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