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Title:   Author  item
                                            MEINELT, THOMAS - Leibniz Instituteitem
                                            SUDOVA, ELISKA - Research Institute Of Fish Culture And Hydrobiologyitem
                                            WIENKE, ANDREAS - Martin Luther Universityitem
                                            Straus, David

                                                         - *Dave*
  Submitted to: European Association of Fish Pathologists
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 6/29/2009
                                    Publication  Date: 9/14/2009
                                    Citation: Meinelt, T., Sudova, E., Wienke, A., Straus, D.L. 2009. Dynamic peracetic acid (PAA) exposure, a treatment strategy against ectoparasites [abstract]. European Association of Fish Pathologists. p.423.Interpretive Summary:
                                Technical Abstract: The search for alternative therapeutic agents is a difficult and laborious task. The use of peracetic acid (PAA) has recently been evaluated as an alternative compound for disinfection (Gustavino et al., 2005). In addition to having a broad antimicrobial spectrum, PAA does not contribute to the formation of disease resistant organisms. Meinelt et al. (2007) and Straus and Meinelt (2009) found PAA to be toxic to free living, infective Ichthyophthirius multifiliis-theronts at very low concentrations. Recently detached I. multifiliis-trophonts, had a higher tolerance to PAA. Trophonts that were allowed to settle to the bottom to form tomonts and developing tomites within the tomont were even more tolerant to PAA-exposure (Meinelt et al., submitted). It is presumed that this tolerance is a result of the developing cyst wall. 

Because PAA degrades in a liquid phase (Zhaoa, 2008), continuous exposure was investigated to treat I. multifiliis in common carp (Cyprinus carpio). Carp from a fish hatchery (RIFCH Vodnany, Czech Republic) were infected with approximately 5000 I. multifiliis-theronts/L. Two groups were treated with 1 ppm PAA (Wofasteril E400, 40% PAA, KESLA PHARMA WOLFEN GmbH, Greppin, Germany) for four days by means of peristaltic pumps. After exposure, the density of Diplozoon paradoxum, Gyrodactylus spp., Dactylogyrus spp., Trichodina spp. and Ichthyobodo necator, originating from the breeding pond, were lowered and I. multifiliis density was significantly reduced.


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