U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Harry K. Dupree Stuttgart National Aquaculture Research Cntr: Stuttgart, AR
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    CareersSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Southeast Area Stuttgart, Arkansas Harry K. Dupree Stuttgart National Aquaculture Research Cntr Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications
- IACUC Summary

Title:   Author  item
                                            BOWKER, JAMES - Us Fish And Wildlife Serviceitem
                                            Straus, David

                                                         - *Dave*item
                                            BOWMAN, MOLLY - Us Fish And Wildlife Serviceitem
                                            CARTY, DAN - Us Fish And Wildlife Serviceitem
                                            DOTSON, MIRANDA - Us Fish And Wildlife Serviceitem
                                            Mitchell, Andrewitem
                                            Farmer, Bradley
  Submitted to: Aquatic Animal Drug Approval Partnership (AADAP)
                                    Publication Type: Research Notes
                                    Publication Acceptance Date: 10/18/2010
                                    Publication  Date: 11/17/2010
                                    Citation: Bowker, J.D., Straus, D.L., Bowman, M.P., Carty, D., Dotson, M., Mitchell, A.J., Farmer, B.D. 2010. The Safety of AQUAFLOR  (50% Florfenicol; Type A Medicated Article) Administered in feed to sunshine bass (female white bass Morone chrysops × male striped bass M. saxatilis). U.S. Fish & Wildlife Service, Aquatic Animal Drug Approval Partnership, Drug Research Information Bulletin 19. 2 p.Interpretive Summary:
                                Technical Abstract: Bacterial diseases are a major problem in aquaculture and account for significant losses of fish (Clarke and Scott 1989; Frerichs and Roberts 1989; Bjorndal 1990). Therefore, the use of antimicrobial therapy plays an important role in aquaculture (Klontz 1987; Alderman 1988).  Florfenicol (FFC) is a potent, broad-spectrum, antibacterial agent with bacteriostatic and bacteriocidal properties that is active against a variety of Gram-positive and Gram-negative bacteria (Horsberg et al. 1996).  

AQUAFLOR® is an aquaculture feed premix containing 50% florfenicol (weight-to-weight).  Worldwide, AQUAFLOR® has been approved in more than 20 countries (e.g., Norway, Japan, Chile, Canada, and the U.S.) to control mortality in a variety of cultured fishes due to diseases associated with infectious pathogens.  In the U.S., the Food and Drug Administration (FDA) has approved AQUAFLOR® for use to control mortality in (1) catfish due to enteric septicemia associated with Edwardsiella ictaluri, (2) freshwater-reared salmonids due to coldwater disease associated with Flavobacterium psychrophilum, and (3) freshwater-reared salmonids due to furunculosis associated with Aeromonas salmonicida (Bowker et al., in press).  In the U.S., the only approved treatment regimen is to administer AQUAFLOR® in feed at 10 mg FFC/kg fish body weight/d for 10 consecutive days.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov