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Title:   Author  item
                                            SCHILLER, I - Federal Veterinary Officeitem
                                            OESCH, B - Prionics Agitem
                                            VORDERMEIER, H - Veterinary Laboratories Agency (VLA)item
                                            Palmer, Mitchellitem
                                            HARRIS, B - US Department Of Agriculture (USDA)item
                                            ORLOSKI, K - US Department Of Agriculture (USDA)item
                                            BUDDLE, B - Agresearchitem
                                            Thacker, Tyleritem
                                            LYASHCHENKO, K - Chembio Diagnostic Systems, Incitem
                                            Waters, Wade
  Submitted to: Transboundary and Emerging Diseases
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 5/17/2010
                                    Publication  Date: 8/1/2010
                                    Citation: Schiller, I., Oesch, B., Vordermeier, H.M., Palmer, M.V., Harris, B.N., Orloski, K.A., Buddle, B.M., Thacker, T.C., Lyashchenko, K.P., Waters, W.R. 2010. Bovine tuberculosis: a review of current and emerging diagnostic techniques in view of their relevance for disease control and eradication. Transboundary and Emerging Diseases. 57(4):205-220.Interpretive Summary: Despite highly successful eradication efforts in several countries, tuberculosis of cattle remains a serious health concern worldwide. Outbreaks in Michigan, California, and Minnesota continue and new cases have been detected in South Dakota and Indiana; demonstrating that the disease is far from eliminated from the United States. This review article provides an overview of current and emerging bovine tuberculosis testing strategies/tools and a vision for incorporation of emerging technologies into the current control/eradication programs. Knowledge presented in this article will be useful for the dissemination of information critical for the advancement of new strategies to be used in the United States tuberculosis eradication program.
                                Technical Abstract: Existing strategies for long standing bovine tuberculosis (bTB) control/eradication campaigns are being reconsidered in many countries due to the development of new testing technologies, increased global trade, continued struggle with wildlife reservoirs of bTB, redistribution of international trading partners/agreements, and emerging financial and animal welfare constraints on herd depopulation. Changes under consideration or newly implemented include: additional control measures to limit risks with imported animals, enhanced programs to mitigate wildlife reservoir risks, re-evaluation of options to manage bTB-affected herds/regions, modernization of regulatory framework(s) to re-focus control efforts, and consideration of emerging testing technologies (i.e., improved or new tests) for use in bTB control/eradication programs. Traditional slaughter surveillance and test/removal strategies will likely be augmented by incorporation of new technologies and more targeted control efforts. The present review provides an overview of current and emerging bTB testing strategies/tools and a vision for incorporation of emerging technologies into the current control/eradication programs.


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