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Title:   Author  item
                                            BOYER, BERT - UNIV. ALASKA HEALTH RES.item
                                            MOHATT, GERALD - UNIV. ALASKA HEALTH RES.item
                                            PLAETKE, ROSEMARIE - UNIV. ALASKA HEALTH RES.item
                                            HERRON, JOHANNA - UNIV. ALASKA HEALTH RES.item
                                            STANHOPE, KIMBER - UC DAVIS, NUTR. DEPT.item
                                            Stephensen, Charlesitem
                                            HAVEL, PETER - UC DAVIS, NUTR. DEPT.
  Submitted to: Obesity
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 3/28/2007
                                    Publication  Date: 11/1/2007
                                    Citation: Boyer, B.B., Mohatt, G.V., Plaetke, R., Herron, J., Stanhope, K.L., Stephensen, C.B., Havel, P.J. 2007. Metabolic Syndrome in Yup'ik Eskimos: The Center for Alaska Native Health Research (CANHR) Study. Obesity. Vol.15 No.11, 2535-2540.Interpretive Summary: Metabolic syndrome is defined by elevated body weight, waist circumference, increased blood pressure, and abnormal serum lipid and glucose levels. The prevalence of these risk factors can vary among different population groups. Metabolic syndrome has been relatively uncommon in Yup’ik Eskimos, perhaps due to dietary and lifestyle differences. However, this study indicates a trend toward a less healthy risk profile and further increases in metabolic syndrome risk factors among Yup’ik Eskimos could lead to increases in the prevalence of type 2 diabetes and cardiovascular disease, once rare in this population.
                                Technical Abstract: Objective: This study investigated the prevalence of metabolic
syndrome and its defining components among Yup’ik
Eskimos.
Research Methods and Procedures: A cross-sectional
study design that included 710 adult Yup’ik Eskimos 18
years of age residing in 8 communities in Southwest Alaska.
The prevalence of metabolic syndrome was determined
using the recently updated Adult Treatment Panel III criteria.
Results: The prevalence of metabolic syndrome in this
study cohort was 14.7%, and varied by sex with 8.6% of the
men and 19.8% of the women having metabolic syndrome.
This is lower than the prevalence of 23.9% in the general
U.S. adult population. The most common metabolic syndrome
components/risk factors were increased waist circumference
and elevated blood glucose. High-density lipoprotein
(HDL) cholesterol levels in Yup’ik Eskimos were
significantly higher, and triglycerides lower than levels reported
in National Health and Nutritional Examination III.
Discussion: Compared with other populations, metabolic
syndrome is relatively uncommon in Yup’ik Eskimos. The
higher prevalence among Yup’ik women is primarily explained
by their large waist circumference, suggesting central
body fat accumulation. Further increases in metabolic
syndrome risk factors among Yup’ik Eskimos could lead to
increases in the prevalence of type 2 diabetes and cardiovascular
disease, once rare in this population.


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