Exhibit 10.28

ANIKA THERAPEUTICS, INC.  NON-EMPLOYEE DIRECTOR COMPENSATION POLICY

The Non-Employee Director Compensation Policy of Anika Therapeutics, Inc., a Massachusetts company (the "Company"), is effective as of
February 1, 2008 (the "Effective Date").

Following
the Effective Date, all non-employee directors shall be paid cash compensation for services provided to the Company as set forth below.

|                       |  | Annual Retainer |        | In-Person
Attendance
Per Meeting |   | Telephonic
Attendance
Per Meeting
|---------------------- |  | --------------- | ------ | -------------------------------- | - | ---------------------------------
|Board                  |  |                 |        |                                  |   |                                  
|Chairman of the Board  |  | $               | 35,000 |                                  | $ | 1,500                            
|Other Directors        |  | $               | 20,000 |                                  | $ | 1,500                            
|Audit Committee        |  |                 |        |                                  |   |                                  
|Committee Chairman     |  | $               | 10,000 |                                  | $ | 1,000                            
|Committee Members      |  | $               | 5,000  |                                  | $ | 1,000                            
|Compensation Committee |  |                 |        |                                  |   |                                  
|Committee Chairman     |  | $               | 8,000  |                                  | $ | 1,000                            
|Committee Members      |  | $               | 4,000  |                                  | $ | 1,000                            
|Nominating Committee   |  |                 |        |                                  |   |                                  
|Committee Chairman     |  | $               | 6,000  |                                  | $ | 1,000                            
|Committee Members      |  | $               | 3,000  |                                  | $ | 1,000                            

The
Annual Retainer will be paid quarterly, in arrears, or upon the earlier resignation or removal of the non-employee director. Amounts owing to non-employee
directors as Annual Retainer shall be annualized, meaning that non-employee directors who join the board during the calendar year, shall receive a pro rated amount based on the number of
calendar days served by such director. Directors serving on committees of the Board shall receive no additional compensation for attending any committee meeting held in connection with a meeting of
the Board of Directors.

The
non-employee directors shall also be eligible to participate in the Company's stock option plans. Following the Effective Date, each person who is initially appointed or
elected to the Board of Directors as a non-employee director shall be eligible to receive a grant of stock appreciation rights of a value of approximately $70,000, based on a Black-Scholes
analysis (the "Initial Director Grant"), which Initial Director Grant shall vest in four equal annual installments from the date of grant. Following the Effective Date, each person who is
re-elected to the Board of Directors as a non-employee director shall be eligible to receive a grant of restricted stock units of a value of approximately $30,000, based on a
Black Scholes analysis (the "Annual Director Grant"), which Annual Director Grant shall vest in three equal annual installments from the date of grant. The Initial Director Grant and Annual Director
Grant shall become immediately exercisable upon the death, disability or retirement of a director who is in good standing or upon a change in control of the Company. Any non-employee
director in good standing who resigns from the Board of Directors shall have all unvested equity accelerated in full. In
addition, the form of stock appreciation rights agreement and restricted stock unit agreement, as applicable, will give directors up to one year following cessation of service as a director to
exercise the awards, as applicable, provided that the director has not been removed for cause. All of the foregoing awards will be granted at fair market value on the date of grant.

The
foregoing compensation will be in addition to reimbursement of all out-of-pocket expenses incurred by directors in attending meetings of the Board of
Directors.

All
non-employee directors shall hold equity of the Company equal to three times (3x) the non-employee director's annual retainer to be achieved within five
(5) years.

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