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Title:   Author  item
                                            Liu, Ge

                                                         - *George*
  Submitted to: Recent Patents on Food, Nutrition and Agriculture
                                    Publication Type: Review Article
                                    Publication Acceptance Date: 10/16/2008
                                    Publication  Date: 10/21/2008
                                    Citation: Liu, G. 2009. Applications and Case Studies of the Next-Generation Sequencing Technologies in Food, Mutrition and Agriculture. Recent Patents on Food, Nutrition & Agriculture. 1(1):75-79.Interpretive Summary:
                                Technical Abstract: Next-generation sequencing technologies are able to produce high-throughput short sequence reads in a cost-effective fashion. The emergence of these technologies has not only facilitated genome sequencing but also changed the landscape of life sciences. Here I survey their major applications ranging from whole-genome sequencing and resequencing, single nucleotide polymorphism (SNP) and structural variation discovery, to mRNA and noncoding RNA profiling and ChIP-seq. These case studies in comparative and functional genomics, epigenomics, and metagenomics are providing a more complete picture of the genome structures and functions. In the near future, we will witness broad impacts of these next-generation sequencing technologies for solving complex biological problems in food, nutrition and agriculture.


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