U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Lee, Sungitem
                                            Lillehoj, Hyunitem
                                            PARK, J - Changwon National Universityitem
                                            JANG, S - Research Institute Of Health And Environmentitem
                                            MORALES, A - Applied Research(INVESTIGACION APLICADA)item
                                            GARCIA, D - Applied Research(INVESTIGACION APLICADA)item
                                            LUCIO, E - Applied Research(INVESTIGACION APLICADA)item
                                            LARIOS, R - Applied Research(INVESTIGACION APLICADA)item
                                            VICTORIA, G - Applied Research(INVESTIGACION APLICADA)item
                                            MARRUFO, D - Applied Research(INVESTIGACION APLICADA)
  Submitted to: Veterinary Parasitology
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 8/1/2009
                                    Publication  Date: 9/15/2009
                                    Citation: Lee, S.H., Lillehoj, H.S., Park, J.W., Jang, S.I., Morales, A., Garcia, D., Lucio, E., Larios, R., Victoria, G., Marrufo, D. 2009. Protective effect of hyperimmune egg yolk Ig Y antibodies against Eimeria tenella and Eimeria maxima infections. Veterinary Parasitology. 163:123-126.Interpretive Summary: This report describes a new method to control avian coccidiosis. 
Avian coccidiosis is caused by several distinct species of Eimeria parasites and cost poultry industry more than $ 3.2 million annual economic loss. Although drugs have been used successfully 
to control coccidiosis, increasing incidence of drug-resistant field strains of Eimeria compels the new strategy to control this infection. In this paper, ARS scientists and scientists at the Investigación Aplicada, S. A. de C. V. (IASA) in Puebla, Mexico work together to develop a commercially applicable new strategy using egg yolk-derived IgY antibodies to feed young birds to prevent avian coccidiosis. The results indicate a very successful strategy that can be fed to young birds with significant reduction of intestinal damage and improved body weight gains in treated birds. Furthermore, orally-administered Eimeria-specific IgY antibodies protective against more than one species of Eimeria. This is the first study that describes the development of commercially available hyperimmune antibodies which provide significant protection against avian coccidiosis in newly hatched chicks.
                                Technical Abstract: Avian coccidiosis is economically the most important parasitic disease of the poultry industry and is caused by intestinal infection with Eimeria spp.  An alternative control strategy potentially applicable to intestinal diseases such as avian coccidiosis involves passive immunization using hyperimmune. The current study was conducted to evaluate the effect of dietary supplementation with a purified IgY fraction of egg yolk (SC) prepared from hens hyperimmunized with Eimeria oocysts on host protective immune responses against Eimeria tenella and Eimeria maxima. Broiler chickens were continuously fed from hatch with standard diets containing SC or a non-supplemented control diet, and orally challenged at day 7 post-hatch with 1.0 × 104 live E. tenella or E. maxima oocysts. Body weight gain between days 0 and 10, fecal oocyst shedding between days 5 and 10 post-infection, and lesion score were determined as parameters of protective immunity.  SC significantly affects body weight gain of the birds infected with E. tenella at 0.02% and 0.05% of diet, and body weight gain of the birds infected with E. maxima at 0.05% of diet.  Among the birds infected with E. tenella, oocyst shedding was reduced in the birds fed 0.05% SC diet (p<0.01).  Lesion score was significantly lower only in the birds given 0.5% SC among the birds infected with 1.0 × 104 E. maxima (p<0.05) compared with the control birds fed the non-supplemented diet. We conclude that passive immunization of chickens with anti-coccidia IgY antibodies may provide protective immunity against coccidiosis due to E. tenella and E. maxima at different concentrations of diet by preventing body weight loss, oocysts production or intestinal infection.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov