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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                    Form 10-K

(X)      Annual report pursuant to Section 13 or 15(d) of the Securities
         Exchange Act of 1934 (Fee Required) for the fiscal year ended December
         31, 2000.

                                       OR

( )      Transition report pursuant to Section 13 or 15(d) of the Securities
         Exchange Act of 1934 (No Fee Required) for the transition period
         from                    to                        .
              ------------------    -----------------------

                           Commission File No. 0-22124

                                NSD Bancorp, Inc.
                                -----------------
             (Exact name of Registrant as specified in its charter)

Commonwealth of Pennsylvania                            25-1616814
(State or other jurisdiction of            (I.R.S. Employer Identification No.)
incorporation or organization)

          5004 McKnight Road, Pittsburgh, Pennsylvania        15237
            (Address of principal executive offices)        (Zip Code)

                                 (412) 231-6900
              (Registrant's telephone number, including area code)

Securities registered pursuant to Section 12(b) of the Act:

    Title of each class             Name of each exchange on which registered

    -------------------             -----------------------------------------

Securities registered pursuant to Section 12(g) of the Act:
                             Common Stock, $1.00 Par Value

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.
                                   YES  X    NO
                                       ---      ---

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K (Section 29.405 of this chapter) is not contained herein, and
will not be contained, to the best of the registrant's knowledge, in definitive
proxy or information statements incorporated by reference in Part III of this
Form 10-K or any amendment to this Form 10-K
                                             ------------

The aggregate market value of Common Stock, $1.00 par value, held by
non-affiliates of March 1, 2001, was $48,167,511.

The number of shares outstanding of the Registrant's Common Stock as of March 1,
2001 was 2,854,371.

Documents Incorporated By Reference:
Portions of the Registrant's Annual Report to Shareholders for the year ended
December 31, 2000 are incorporated by reference into Parts I, II and IV.

Portions of the Registrant's Proxy Statement for the Annual Shareholders'
Meeting to be held on April 24, 2001, are incorporated by reference into Part
III.

                        Number of Pages in this Filing 6

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                                NSD BANCORP, INC.
                                    FORM 10-K
                   For the Fiscal Year Ended December 31, 2000

                                      INDEX

                                                                            Page
Part I

  Item 1.    Business                                                         1
  Item 2.    Properties                                                       2
  Item 3.    Legal Proceedings                                                3
  Item 4.    Submission of Matters to a Vote of Security Holders              3
Part II
  Item 5.    Market for Registrant's Common Equity and Related
             Stockholder Matters                                              3

  Item 6.    Selected Financial Data                                          3
  Item 7.    Management's Discussion and Analysis of Financial condition
             and Results of Operations                                        3

  Item 7a.   Quantitative and Qualitative Disclosure About Market Risk        3

  Item 8.    Financial Statements and Supplementary Data                      3

  Item 9.    Changes in and Disagreements With Accountants on Accounting
             and Financial Disclosure                                         3

Part III

  Item 10.   Directors and Executive Officers of the Registrant               4

  Item 11.   Executive Compensation                                           4

  Item 12.   Security Ownership of Certain Beneficial Owners and
             Management                                                       4

  Item 13.   Certain Relationships and Related Transactions                   4

Part IV

  Item 14.   Exhibits, Financial Statement Schedules and Reports on
             Form 8-K                                                         4

             Signatures                                                       6


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Part I

ITEM 1.  BUSINESS

NSD Bancorp, Inc. (the "Corporation") is a registered bank holding company
organized under the Pennsylvania Business Corporation Law and is registered
under the Bank Holding Company Act of 1956, as amended. The Corporation became a
holding company upon acquiring all of the outstanding shares of NorthSide Bank
through an exchange of stock on August 2, 1993. At December 31, 2000, the
Corporation had total assets, deposits and shareholders' equity of $435,619,403,
$307,077,815 and $33,640,586, respectively. Full-time equivalent employees of
the Corporation were 139 at December 31, 2000.

The Corporation derives substantially all of it's income from banking and
bank-related services provided by its wholly-owned subsidiary, NorthSide Bank
(the Bank). The Bank is a state chartered bank with ten branch locations at
December 31, 2000. The Corporation is subject to periodic examination and
regulation by the Federal Reserve Bank. As a state chartered bank, NorthSide
Bank is subject to periodic examination and regulation by the Pennsylvania
Department of Banking and the FDIC. The Bank is a full-service bank offering
retail banking services, such as demand, savings and time deposits, money market
accounts, secured and unsecured loans, mortgage loans, safe deposit boxes,
holiday club accounts, wire transfers, money orders and traveler's checks.
Services to commercial customers are also offered, including real estate
mortgage loans, lines of credit, inventory and accounts receivable financing and
equipment leasing. NorthSide Bank operates nine automatic teller machines to
provide 24 hour banking services to its customers. The Bank's deposits are
derived from more than 50,000 individual and commercial accounts. There is no
single depositor or group of related depositors, the loss of whom would have a
materially adverse effect on the business of the Bank. The Bank's loans are not
concentrated within a single industry or group of related industries to any
material extent.

The Bank's service area includes the northern portion of Allegheny County and
southern Butler County where it competes with many other banks. The Bank also
competes with regional bank and trust companies, credit unions, savings and loan
associations, consumer finance companies, insurance companies and direct lending
agencies of the government throughout its service area. Banks compete for all
types of deposit and loan accounts, with banks and trust companies having the
additional power to compete for trust accounts. Savings and loan associations
offer savings and time deposit services as well as installment and mortgage
loans.

Credit unions also compete with the Bank for savings and time deposit accounts
and for installment loan accounts. Consumer finance companies provide personal
installment loan services in direct competition with the Bank.

The Bank's business is not seasonal in nature, nor does it depend on any single
customer or a few customers, the loss of any one or more of which would be a
materially adverse effect on its business. A further description of the
Corporation's business and discussion of operations is set forth on page 9 in
the Corporation's 2000 Annual Report to Shareholders included in this Form 10-K
as Exhibit 13 which description is incorporated herein by reference.







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ITEM 2.  PROPERTIES

The Corporation's principal office is located at 5004 McKnight Road, Pittsburgh,
Pennsylvania. The Bank's main office is located at 100 Federal Street,
Pittsburgh, Pennsylvania. Including the main office, the Bank has a total of ten
branch offices located as listed below. The Bank owns the four-story building
located on Federal Street, and a parking lot adjacent to the building. The Bank
also owns its Cranberry Township, Ross Township, Pine Creek and West View branch
offices, although it leases the land on which the Pine Creek Shopping Center
branch office is located. The Bank's Hampton Township, McCandless Township,
Allegheny Professional Building, Duncan Manor and Pittsburgh Cultural District
branch offices and the Pine Creek Shopping Center land are operated under leases
that contain various renewal option periods extending through September, 2005.

                            Location Name and Address
                            -------------------------
                              Pittsburgh-North Side
                               100 Federal Street
                              Pittsburgh, PA 15212

                         Allegheny Professional Building
                              490 East North Avenue
                              Pittsburgh, PA 15212

                                    West View
                                728 Center Avenue
                               West View, PA 15229

                               McCandless Township
                         Perry Highway and Ingomar Road
                              McCandless, PA 15237

                               Cranberry Township
                          Route 19N at St. Francis Way
                               Cranberry, PA 16066

                                Hampton Township
                            Shoppers Plaza at Route 8
                                Hampton, PA 15101

                                    Ross Park
                               5004 McKnight Road
                              Pittsburgh, PA 15237

                                   Pine Creek
                           Pine Creek Shopping Center
                               9805 McKnight Road
                              McCandless, PA 15237

                                  Duncan Manor
                                  Duncan Plaza
                               1701 Duncan Avenue
                             Allison Park, PA 15101

                          Pittsburgh Cultural District
                               701 Liberty Avenue
                              Pittsburgh, PA 15222


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ITEM 3.  LEGAL PROCEEDINGS

The Corporation is subject to a number of asserted and unasserted potential
legal claims encountered in the normal course of business. In the opinion of
management, there is no present basis to conclude that the resolution of these
claims will have a material adverse effect on the Corporation's consolidated
financial position or results of operations.

ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

No matter was submitted by the Corporation to its shareholders through the
solicitation of proxies or otherwise during the fourth quarter of the fiscal
year covered by this report.

PART II

ITEM 5.  MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED STOCKHOLDER MATTERS

The Corporation's Common Stock is traded on the NASDAQ National Market System
under the symbol NSDB. The information set forth under the captions "Regulatory
Restrictions" and "Sales Price and Cash Dividends per Share" on pages 20 and 40,
respectively, of the 2000 Annual Report is incorporated herein by reference. As
of March 13, 2001, the Corporation had 402 shareholders of its Common Stock.

ITEM 6.  SELECTED FINANCIAL DATA

Incorporated by reference is the information presented on pages 26 and 29 of the
2000 Annual Report.

ITEM 7.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
         RESULTS OF OPERATIONS

Incorporated by reference is the information presented on pages 28 to 43 of the
2000 Annual Report.

ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURE ABOUT MARKET RISK

Incorporated by reference to the information presented on pages 41 to 42 of the
2000 Annual Report attached as Exhibit 13 hereto.

ITEM 8.  FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

Incorporated by reference is the information presented on pages 4 to 26 of the
2000 Annual Report.

ITEM 9.  CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND
         FINANCIAL DISCLOSURE

None.







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PART III

ITEM 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

Incorporated by reference is the information presented on pages 3,4 and 5 of the
Proxy Statement for the Annual Shareholders Meeting to be held April 24, 2001.

ITEM 11.  EXECUTIVE COMPENSATION

Incorporated by reference is the information presented on pages 5, 6 ,7 and 8 of
the Proxy Statement for the Annual Shareholders Meeting to be held on April 24,
2001.

ITEM 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

Incorporated by reference is the information presented on pages 3, 9, 11 and 12
of the Proxy Statement for the Annual Shareholders Meeting to be held on April
24, 2001.

ITEM 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

Incorporated by reference is the information presented on page 8 of the Proxy
Statement for the Annual Shareholders Meeting to be held on April 24, 2001.

PART IV

ITEM 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

CONSOLIDATED FINANCIAL STATEMENTS FILED:
The consolidated financial statements and report of the Registrant's independent
accountant thereon are incorporated by reference to the pages indicated in the
said Annual Report.

CONSOLIDATED FINANCIAL STATEMENTS:
NSD Bancorp, Inc. and Subsidiary
         Consolidated Balance Sheets,  page 4
         Consolidated Statements of Income,  page 5
         Consolidated Statements of Cash Flows,  page 6
         Consolidated Statements of Comprehensive Income, page 7
         Consolidated Statements of Changes in Shareholders' Equity, page 8
         Notes to Consolidated Financial Statements, pages 9-25 Independent
         Auditor's Report, page 27

CONSOLIDATED FINANCIAL STATEMENT SCHEDULES:
Schedules normally required on Form 10-K are omitted since the required
information is either not applicable, not deemed material or is shown in the
respective consolidated financial statements or in the notes thereto.






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EXHIBITS

   3a.         Articles of Incorporation of NSD Bancorp, Inc. filed as Exhibit
               3a to NSD Bancorp, Inc.'s Form S-4 filed March 9, 1993
               (Registration No. 33-59242), is incorporated herein by reference.

   3b.         Bylaws of NSD Bancorp, Inc. filed as Exhibit 3b to NSD Bancorp,
               Inc.'s Form S-4 filed March 9, 1993 (Registration No. 33-59242),
               is incorporated herein by reference.

   10A.        Employment agreement, dated July 1, 1993 between NSD Bancorp,
               Inc. and Lloyd Gibson filed as exhibit 10D to NSD Bancorp, Inc.'s
               Form 10-K for the fiscal year ended December 31, 1993 is
               incorporated herein by reference.

   10B.        NSD Bancorp, Inc. 1994 Stock Option Plan filed as Exhibit 4.1 to
               NSD Bancorp, Inc.'s Form S-8 filed April 27, 1994 is incorporated
               herein by reference.

   10C.        NSD Bancorp, Inc. 1994 Non-Employee Director Stock Option Plan
               filed as Exhibit 4.1 to NSD Bancorp, Inc.'s Form S-8 filed April
               27, 1994 is incorporated herein by reference.

   11.         Statement re: Computation of Earnings Per Share (incorporated by
               reference to p. 11 of 2000 Annual Report, attached as Exhibit 13,
               hereto.)

   13.         2000 Annual Report to Shareholders is presented within.

   21.         Subsidiaries of the Registrant are presented within.

   23.1        Consent of Deloitte & Touche LLP, Independent Certified Public
               Accountants is presented within.



REPORTS ON FORM 8-K

       None.






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                                   SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange
Act of 1934, the registrant has duly caused this report to be signed on its
behalf by the undersigned, thereunto duly authorized.

                                                    NSD BANCORP, INC.
                                                    ----------------
                                                      (Registrant)

Dated:   March 27, 2001                             By   /S/  Lloyd G. Gibson
                                                        -----------------------
                                                        Lloyd G. Gibson
                                                        President and Chief
                                                        Executive Officer

Pursuant to the requirements of the Securities Exchange Act of 1934, this report
has been signed below by the following persons on behalf of the registrant and
in the capacities indicated on March 24, 2000:

/S/ Lawrence R. Gaus             Lawrence R. Gaus, Chairman of the
----------------------------     Board, Director

/S/ Lloyd G. Gibson              Lloyd G. Gibson, President and Chief Executive
----------------------------     Officer, Director (Principal Executive
                                 Officer)

/S/ James P. Radick              James P. Radick, Treasurer
----------------------------     (Principal Financial and Accounting Officer)

/S/ William R. Baierl            William R. Baierl, Director
----------------------------

/S/ Grant A. Colton Jr.          Grant A. Colton, Jr., Director
----------------------------

/S/ Nicholas C. Geanopulos       Nicholas C. Geanopulos, Director
----------------------------

/S/ Gus P. Georgiadis            Gus P. Georgiadis, Director
----------------------------

/S/ Charles S. Lenzner           Charles S. Lenzner, Director
----------------------------

/S/ Kenneth L. Rall              Kenneth L. Rall, Director
----------------------------

/S/ Arthur J. Rooney II          Arthur J. Rooney, II, Director
----------------------------







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