U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BHNRC) Beltsville Human Nutrition Research Center Food Components and Health Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Stote, Kimitem
                                            PAUL, DAVID - UNIV OF IDAHOitem
                                            HARRIS, GABRIEL - NORTH CAROLINA STATE UNIVitem
                                            Rumpler, Williamitem
                                            Clevidence, Beverlyitem
                                            Baer, David
  Submitted to: Journal of Nutrition
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 5/16/2011
                                    Publication  Date: 8/1/2011
                                    Citation: Stote, K.S., Paul, D.R., Harris, G.K., Rumpler, W.V., Clevidence, B.A., Baer, D.J. 2011. Whey protein but not soy protein supplementation alters body weight and composition in free-living overweight and obese adults. Journal of Nutrition. 141:1489-94.Interpretive Summary: The macronutrient that appears to be most satiating is dietary protein and the source of dietary protein may influence satiety and food intake. Few long-term research studies have investigated the effects of whey protein, a protein found in dairy products, on biomarkers of satiety, such as plasma ghrelin, in overweight and obese adults. Ghrelin is a hormone that is produced primarily by the stomach and small intestine; it may serve as a hunger signal. The effect of consumption of supplemental whey protein, soy protein, and an isocaloric amount of carbohydrate on subjective and physiologic biomarkers of satiety in free-living overweight and obese adults was evaluated. Ninety subjects were randomly assigned for 23 weeks to one of three treatments along with consuming their free-living diet: 1) 60 g/d of whey protein, 2) 60 g/d of soy protein, or 3) a carbohydrate control group. The treatments were consumed as a beverage with breakfast and the evening meal. Biomarkers measured at baseline and at the end of the study included ghrelin, peptide YY, leptin, and adiponectin. These biomarkers are associated with hunger and energy regulation. Subjective satiety was assessed daily by the use of visual analog scales which evaluate hunger, desire to eat, and fullness. Dietary intake was determined by 24-h dietary recalls collected every 10 days. Results showed that after 23 weeks, subjects consuming supplemental whey protein had lower ghrelin concentrations than did subjects consuming soy protein or an isocaloric carbohydrate treatment. No significant treatment effects were observed on peptide YY, leptin, adiponectin, or energy and macronutrient intakes. Whey protein suppressed ghrelin concentrations when compared with soy protein and the carbohydrate treatment. These findings indicate that whey protein supplementation may be more satiating than soy protein and carbohydrate in free-living overweight and obese adults. These findings will be important to scientists interested in components in dairy foods and their effects on hunger, satiety, and food intake regulation.
                                Technical Abstract: The most satiating macronutrient appears to be dietary protein; the source of the dietary protein may influence satiety and food intake. Few long-term clinical trials have investigated the effects of whey protein on biomarkers of satiety, such as plasma ghrelin, in overweight and obese adults. The effect of consumption of supplemental whey protein, soy protein, and an isocaloric amount of carbohydrate on subjective and physiologic biomarkers of satiety in free-living overweight and obese adults was evaluated. Ninety subjects were studied in a double-blinded parallel design. The subjects were randomly assigned for 23 weeks to one of three treatment groups along with consuming their free-living diet: 1) 60 g/d of whey protein, 2) 60 g/d of soy protein, or 3) a carbohydrate control group. The treatments were consumed as a beverage with breakfast and the evening meal. Biomarkers measured at baseline and at the end of the study included ghrelin, peptide YY, leptin, and adiponectin. Subjective satiety was assessed daily by use of visual analog scales. Dietary intake was determined by 24-h dietary recalls collected every 10 days. Results showed that after 23 weeks, subjects consuming supplemental whey protein had lower ghrelin concentrations than did subjects consuming soy protein or the isocaloric carbohydrate treatment. No significant treatment effects were observed on peptide YY, leptin, adiponectin, and energy and macronutrient intakes. Whey protein suppressed ghrelin concentrations when compared with soy protein and the isocaloric carbohydrate treatment. Whey protein supplementation may be more satiating than soy protein and carbohydrate in free-living overweight and obese adults.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov