U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Natural Products Utilization Research: Oxford, MS
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Location Research Units
                        National Sedimentation Laboratory
                                    Natural Products Utilization Research Unit
                                    Water Quality and Ecology Research Unit
                                    Watershed Physical Processes Research UnitSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Southeast Area Oxford, Mississippi Natural Products Utilization Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Cantrell, Charlesitem
                                            MAMONOV, LEONID - INST. OF PLANT PHYS.item
                                            RYABUSHKINA, NATALJA - INST. OF PLANT PHYS.item
                                            KUSTOVA, TATYANA - INST. OF PLANT PHYS.item
                                            FISCHER, NIKOLAUS - UNIVERSITY OF MISSISSIPPIitem
                                            Schrader, Kevin
  Submitted to: Archives for Organic Chemistry (ARKIVOC)
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 12/1/2006
                                    Publication  Date: 1/1/2007
                                    Citation: Cantrell, C.L., Mamonov, L.K., Ryabushkina, N., Kustova, T.S., Fischer, N.H., Schrader, K. 2007. Bioassay-guided Isolation of Anti-Algal Constituents from Inula Helenium and Limonium Myrianthum. Archives for Organic Chemistry (ARKIVOC).  vii:65-75.Interpretive Summary: Over 70 crude plant extracts, primarily from Kazakhstan, were screened against the freshwater phytoplanktons Oscillatoria perornata and Selenastrum capricornutum.  Extracts from Limonium myrianthum and Inula helenium both demonstrated selective inhibition against the cyanobacterium O. perornata compared to activity against the beneficial green alga S. capricornutum.  This odor-producing cyanobacterium, Oscillatoria perornata, has been attributed as the primary cause of off-flavor in pond-raised catfish in west Mississippi and elsewhere in the United States.  Natural compounds were isolated from these active plant extracts and found to selectively inhibit the growth of O. perornata.
                                Technical Abstract: Over 70 crude plant extracts, primarily from Kazakhstan, were screened against the freshwater phytoplanktons Oscillatoria perornata and Selenastrum capricornutum.  Extracts from Limonium myrianthum and Inula helenium both demonstrated selective inhibition against the odor-producing cyanobacterium O. perornata compared to activity against the green alga S. capricornutum.  Bioassay-guided fractionation of the L. myrianthum dichloromethane extract resulted in the identification of nepodin, torachrysone, chrysophanol, and physcion.  Nepodin demonstrated the desired selective inhibition with lowest-complete-inhibition concentration values of 100 ug/mL and >100 ug/mL towards O. perornata and S. capricornutum, respectively.  Similarly, chrysophanol also demonstrated the desired selective inhibition with lowest-complete-inhibition concentration values of 10 ug/mL and >100 ug/mL, respectively.  Bioassay-guided fractionation of the I. helenium hexane extract resulted in the isolation of alantolactone, isoalantolactone, and 11 aH,13-dihydroisoalantolactone.  Activities of these three isolated constituents as well as those of synthetic isomers are reported.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov