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Title:   Author  item
                                            Nicholson, Ericitem
                                            Richt, Juergen
  Submitted to: Encyclopedia of Animal Science
                                    Publication Type: Book / Chapter
                                    Publication Acceptance Date: 11/30/2005
                                    Publication  Date: 3/27/2006
                                    Citation: Nicholson, E.M., Richt, J.A. 2003. Transmissible spongiform encephalopathies: detection & diagnosis. Encyclopedia of Animal Science [online]. 1(1). http://www.dekker.com/sdek/abstract~db=enc~content=a713617959.Interpretive Summary:
                                Technical Abstract: This review summarizes the basic approaches for transmissible spongiform encephalopathies (TSEs) detection and diagnosis.  The unusual nature of TSEs limits the available diagnostic repertoire.  Recent interest in the detection and diagnosis of TSEs has resulted in a variety of validated rapid diagnostic methodologies that have proven to be robust in clinical diagnostic settings.  Confirmatory tests are still required and entail specialized equipment and knowledge.  At this time all validated tests require tissues only available post mortem.  Ante mortem diagnostic tests are highly sought after but to date no broadly applicable, validated ante mortem method has been developed.


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