U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            WEAVER, DANIEL - BEE POWER, L.Pitem
                                            ANZOLA, JUAN - TEXAS A&M UNIVitem
                                            Evans, Jayitem
                                            REESE, JUSTIN - TEXAS A&M UNIVitem
                                            CHILDS, KEVIN - TEXAS A&M UNIVitem
                                            REID, JEFFERY - BAYLOR COLLEGE OF MEDitem
                                            ZDOBNOV, EVGENY - EMBL HEIDELBERG, GERMANYitem
                                            SAMANTA, MANOJ - NASA-AMES MOFFET FLD, CAitem
                                            MILLER, JONATHAN - BAYLOR COLLEGE OF MEDitem
                                            ELSIK, CHRISTINE - TEXAS A&M UNIV
  Submitted to: Genome Biology
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 1/7/2007
                                    Publication  Date: 6/1/2007
                                    Citation: Weaver, D.B., Anzola, J.M., Evans, J.D., Reese, J., Childs, K.L., Reid, J., Zdobnov, E., Samanta, M., Miller, J., Elsik, C.G. 2007. Computational and transcriptional evidence for microRNAs in the honeybee genome. Genome Biology. 8(6):R97.Interpretive Summary: Genomic projects allow a deep understanding of agricultural organisms, including the honey bee, by presenting the entire genetic blueprint with which these organisms must grow and reproduce. In the case of the honey bee, recent genomic advances involve pollination and other behaviors, disease resistance, and the production of healthy queens and workers. These advances are now in use as diagnostic tools, and soon will be used in breeding programs aimed at keeping honey bees as a key pollinator of agricultural crops.  One of the most unexpected recent discoveries from genome projects is the importance of tiny sections of RNA that play a huge role in regulating genetic information.  Our description here of such ‘microRNA’s’ in the honey bee is aimed at understanding their impacts on honey bee biology.  This analysis should tie to together honey bee traits involving development, behavior, and disease resistance, providing researchers with a new tool for understanding and enhancing these traits in an important agricultural species.
                                Technical Abstract: Noncoding microRNAs (miRNAs) are key regulators of gene expression in eukaryotes. Insect miRNAs help regulate the levels of proteins involved with development, metabolism, and other life history traits.  The recently sequenced honeybee genome provides an opportunity to detect novel miRNAs in both this species and others, and begin to infer the roles of miRNAs in honeybee development. Three independent computational surveys of the assembled honeybee genome identified a total of 65 non-redundant candidate miRNAs, several of which appear to have previously unrecognized orthologs in the Drosophila genome.  A subset of these candidate miRNAs were detected as mature transcripts.  Among those canonical miRNAs tested in Apis mellifera, miR-1, miR-2, miR-9a, miR-9b, miR-10, miR-71, miR-310 and bantam exhibited evidence of expression in honeybee.  We also developed evidence of transcription in honeybee for several novel miRNAs. Interestingly, the transcript abundance for many of these mature miRNAs displayed caste or age-related differences.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov