U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Kapczynski, Darrellitem
                                            Wise, Markitem
                                            King, Daniel
  Submitted to: Avian Diseases
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 2/16/2006
                                    Publication  Date: 9/1/2006
                                    Citation: Kapczynski, D.R., Wise, M., King, D.J. 2006. Susceptibility and protection of naive and vaccinated racing pigeons (Columba liva) against exotic Newcastle disease virus from the California 2002-03 outbreak. Avian Diseases. 50(3):336-341.Interpretive Summary: Newcastle disease is considered to be one of the most important viral diseases of poultry worldwide.  The role of free-flying birds to spread the virus to commercial poultry has been established.  The objectives of the present study were to extend the knowledge of susceptibility and protection of racing pigeons against U.S. exotic Newcastle disease (END) virus.  The results indicate that pigeons are less susceptible to END than chickens and display few clinical signs of disease following exposure to the virus.  Although vaccination decreases the amount of virus shed, the birds will continue to shed the virus up to 2 weeks after infection.
                                Technical Abstract: The susceptibility,  immune response and protection to challenge following vaccination in racing pigeons was assessed using the 2002-03 exotic Newcastle disease (END) virus responsible for the most recent major outbreak in southern California. Immunologically naïve pigeons appeared resistant to disease, regardless of dose, following a natural route of exposure. Twenty percent morbidity was observed in each group of birds receiving between 102.1-108.1 EID50/bird, with one bird succumbing to challenge in the 108.1EID50/bird group at day 12 post-inoculation .  Although resistant to disease, birds in all groups continued to shed virus from either oral or cloacal route at the end of the 14-day sampling period, and seroconversion was only observed in birds receiving > 106.1EID50.  Single or double vaccination of juvenile and adult birds with pigeon paramyxovirus virus-type 1 (PPMV-1) vaccine followed by END challenge with 106.1 EID50/bird decreased the duration, incidence and viral load.  A positive correlation was observed between the presence of hemagglutination-inhibiting antibody titers at challenge and decreased viral.  Overt clinical signs of disease were not observed in any PPMV-1 vaccinated birds following challenge.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov