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Title:   Author  item
                                            Richt, Juergenitem
                                            Hamir, Amiraliitem
                                            Kunkle, Robertitem
                                            Nicholson, Ericitem
                                            Greenlee, Justinitem
                                            MILLER, JANICE - ARS RETIREDitem
                                            CUTLIP, RANDALL - ARS RETIREDitem
                                            DAVIS, ARTHUR - NVSL APHIS USDA, AMES, IAitem
                                            HALL, S - NVSL APHIS USDA, AMES, IA
  Submitted to: Rushmore Conference on Mechanisms in Pathogenesis of Enteric Diseases
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 9/5/2005
                                    Publication  Date: 9/29/2005
                                    Citation: Richt, J.A., Hamir, A.N., Kunkle, R.A., Nicholson, E.M., Greenlee, J.J., Miller, J.M., Cutlip, R., Davis, A.J., Hall, S.M. 2005. Natural and experimental prion diseases of cattle [abstract]. Third International Rushmore Conference on Enteric Diseases. Paper No. 14.Interpretive Summary:
                                Technical Abstract: Scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease (CWD), and transmissible mink encephalopathy (TME) are transmissible spongiform encephalopathies (TSEs) of animals. Scrapie naturally affects sheep and goats, CWD elk and deer, TME ranched mink and BSE cattle. BSE is the only animal TSE which has been shown to have a causal relationship with a human TSE, called variant Creutzfeldt-Jakob disease (vCJD). In the past decade, experimental transmission of scrapie, CWD and TME into cattle has been performed at the National Animal Disease Center. Clinicopathological and molecular features of these experimental prion diseases in cattle will be described in detail and compared to the two BSE cases identified in U.S. cattle.


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