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Title:   Author  item
                                            Smith, Daviditem
                                            Anderson, Robin
  Submitted to: Meeting Proceedings
                                    Publication Type: Proceedings
                                    Publication Acceptance Date: 7/7/2005
                                    Publication  Date: 9/6/2005
                                    Citation: Smith, D.J., Anderson, R.C. 2005. Effect of sodium [36Cl]chlorate dose on total radioactive residues and residues of parent chlorate in swine. Proceedings of the 6th International Symposium on the Epidemiology & Control of Foodborne Pathogens in Pork (SafePork 2005), Sept. 6-9, 2005, Rohnert Park, CA, pp. 142-144.Interpretive Summary:
                                Technical Abstract: Sodium chlorate effectively reduces the numbers of gram-negative pathogens in gastrointestinal tracts of live animals when administered in the 24 to 72 hour period prior to slaughter. It is believed that a chlorate-based product could be a cost-effective and efficient method to reduce the contamination of carcasses during animal processing. The purpose of this study was to determine a dose of sodium chlorate in swine that would result in chlorate residues below FDA CVM-estimated safe tissue concentrations.  Three sets of swine (one barrow and one gilt each) were dosed with 20, 40, or 60 mg/kg sodium [36Cl]chlorate dissolved in drinking water during a 24-hour exposure period. Animals were slaughtered after a 24-hour withdrawal period and edible tissues were removed and analyzed for chlorate content. Total radioactive residues and chlorate residues in edible tissues and excreta of swine will be reported.


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