# Patent

## Title
Method for the improved use of the production potential of transgenic plants

## Abstract

The invention relates to a method for improving the utilization of the production potential of transgenic plants by treating the plant with an effective amount of at least one compound of the formula (I)




in which

R1 and A have the meanings given in the description.

## Background
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a §371 National Stage Application of PCT/EP2008/007605 filed Sep. 13, 2008, which claims priority to European Application 10 2007 045 921.3 filed Sep. 26, 2007.
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to a method for improving the utilization of the production potential of transgenic plants.
2. Description of Related Art
In recent years, there has been a marked increase in the proportion of transgenic plants in agriculture, even if regional differences are still noticeable to date. Thus, for example, the proportion of transgenic maize in the USA has doubled from 26% to 52% since 2001, while transgenic maize has hardly been of any practical importance in Germany. However, in other European countries, for example in Spain, the proportion of transgenic maize is already about 12%.
Transgenic plants are employed mainly to utilize the production potential of respective plant varieties in the most favourable manner, at the lowest possible input of production means. The aim of/be genetic modification of the plants is in particular the generation of resistance in the plants to certain pests or harmful organisms or else herbicides and also to abiotic stress (for example drought, heat or elevated salt levels). It is also possible to modify a plant genetically to increase certain quality or product features, such as, for example, the content of selected vitamins or oils, or to improve certain fibre properties.
Herbicide resistance or tolerance can be achieved, for example, by incorporating genes into the useful plant for expressing enzymes to detoxify certain herbicides, so that a relatively unimpeded growth of these plants is possible even in the presence of these herbicides for controlling broad-leaved weeds and weed grasses. Examples which may be mentioned are cotton varieties or maize varieties which tolerate the herbicidally active compound glyphosate (Roundup®), (Roundup Ready®. Monsanto) or the herbicides glufosinate or oxynil.
More recently, there has also been the development of useful plants comprising two or more genetic modifications (“stacked transgenic plants” or multiply transgenic crops). Thus, for example, Monsanto has developed multiply transgenic maize varieties which are resistant to the European corn borer (Ostrinia nubilalis) and the Western corn rootworm (Diabrotica virgifera). Also known are maize and cotton crops which are both resistant to the Western corn rootworm and the cotton bollworm and tolerant to the herbicide Roundup®.
SUMMARY OF THE INVENTION
It has now been found that the utilization of the production potential of transgenic useful plants can be improved even more by treating the plants with one or more compounds of the formula (I) defined below. Here, the term “treatment” includes all measures resulting in a contact between these active compounds and at least one plant part. “Plant parts” are to be understood as meaning all above-ground and below-ground parts and organs of plants, such as shoot, leaf, flower and root, by way of example leaves, needles, stalks, stems, flowers, fruit bodies, fruits and seed, and also roots, tubers and rhizomes. The plant parts also include harvested material and also vegetative and generative propagation material, for example cuttings, tubers, rhizomes, slips and seed.


DETAILED DESCRIPTION OF A PREFERRED EMBODIMENT
Compounds of the formula (I)




in which

    A represents pyrid-2-yl or pyrid-4-yl, or represents pyrid-3-yl which is optionally substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy, or represents pyridazin-3-yl which is optionally substituted in the 6-position by chlorine or methyl, or represents pyrazin-3-yl or represents 2-chloropyrazin-5-yl or represents 1,3-thiazol-5-yl which is optionally substituted in the 2-position by chlorine or methyl, or
    A represents a pyrimidinyl, pyrazolyl, thiophenyl, oxazolyl, isoxazolyl, 1,2,4-oxadiazolyl, isothiazolyl, 1,2,4-triazolyl or 1,2,5-thiadiazolyl radical which is optionally substituted by fluorine, chlorine, bromine, cyano, nitro, C1-C4-alkyl (which is optionally substituted by fluorine and/or chlorine), C1-C3-alkylthio (which is optionally substituted by fluorine and/or chlorine) or C1-C3-alkylsulphonyl (which is optionally substituted by fluorine and/or chlorine),

or

    A represents a radical






in which

    X represents halogen, alkyl or haloalkyl,
    Y represents halogen, alkyl, haloalkyl, haloalkoxy, azido or cyano, and
    R1 represents alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, halocycloalkyl, alkoxy, alkoxyalkyl or halocycloalkylalkyl,

and their insecticidal action are known from the prior art (cf. EP 0 539 588, WO 2007/115644, WO 2007/115643. WO 2007/115646).



From these documents, the person skilled in the art will be familiar with processes for preparing and methods for using compounds of the formula (I) and with the action of compounds of the formula (I).
Preferred sub-groups for the compounds of the formula (I) mentioned above are listed below.

    A preferably represents 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-methylpyrid-3-yl, 6-tritluoromethylpyrid-3-yl, 6-trifluoromethoxypyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl or 2-methyl-1,3-thiazol-5-yl, 2-chloropyrimidin-5-yl, 2-trifluoromethylpyrimidin-5-yl, 5,6-difluoropyrid-3-yl, 5-chloro-6-fluoropyrid-3-yl, 5-bromo-6-fluoropyrid-3-yl, 5-iodo-6-fluoropyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromo-pyrid-3-yl, 5-fluoro-6-iodopyrid-3-yl, 5-chloro-6-iodopyrid-3-yl, 5-bromo-6-iodopyrid-3-yl, 5-methyl-6-fluoropyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-bromopyrid-3-yl, 5-methyl-6-iodopyrid-3-yl, 5-difluoromethyl-6-fluoropyrid-3-yl, 5-difluoromethyl-6-chloropyrid-3-yl, 5-difluoromethyl-6-bromopyrid-3-yl or 5-difluoromethyl-6-iodopyrid-3-yl.
    R1 preferably represent optionally fluorine-substituted C1-C5-alkyl, C2-C5, C3-C5-cycloalkyl, C3-C5-cycloalkylalkyl or C1-C5-alkoxy.
    A particularly preferably represents the radical 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl, 2-chloropyrimidin-5-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromopyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-chloro-6-iodopyrid-3-yl or 5-difluoromethyl-6-chloropyrid-3-yl radical.
    R1 particularly preferably represents methyl, methoxy, ethyl, propyl, vinyl, allyl, propargyl, cyclopropyl, 2-fluoroethyl, 2,2-difluorethyl or 2-fluorocyclopropyl.
    A very particularly preferably represents the radical 6-U 3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 2-chloro-1,3-thiazol-5-yl or 5,6-dichloropyrid-3-yl.
    R1 very particularly preferably represents methyl, cyclopropyl, methoxy, 2-fluor thy or 2,2-difluoroethyl.
    A most preferably represents the radical 6-chloropyrid-3-yl or 5-fluoro-6-chloropyrid-3-yl.
    R1 most preferably represents methyl, 2-fluoroethyl or 2,2-difluoroethyl.


In a prominent group of compounds of the formula (I), A represents 6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I), A represents 6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I), A represents 6-chloro-1,4-pyridazin-3-yl




In a further prominent group of compounds of the formula (I), A represents 2-chloro-1,3-thiazol-5-yl




In a further prominent group of compounds of the formula (I). A represents 5-fluoro-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I), A represents 5-fluoro-6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I), A represents 5,6-dichloropyrid-3-yl




In a further prominent group of compounds of the formula (I), R1 represents methyl.
In a further prominent group of compounds of the formula (I), R1 represents ethyl.
In a further prominent group of compounds of the formula (I), R1 represents cyclopropyl.
In a further prominent group of compounds of the formula (I), R1 represents 2-fluoroethyl.
In a further prominent group of compounds of the formula (I). R1 represents 2,2-difluoroethyl.
The radical definitions and illustrations listed above in general or listed in preferred ranges can be combined with one another as desired, i.e. including between the particular preferred ranges.
Preference is given in accordance with the invention to compounds of the formula (I) in which a combination of the definitions listed above as preferred is present.
Particular preference is given in accordance with the invention to compounds of the formula (I) in which a combination of the definitions listed above as particularly preferred is present.
Very particular preference is given in accordance with the invention to compounds of the formula (I) in which a combination of the definitions listed above as very particularly preferred is present.
A preferred subgroup of the compounds of the formula (I) are those of the formula (I-a)




in which

    B represents pyrid-2-yl or pyrid-4-yl, or represents pyrid-3-yl which is optionally substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy, or represents pyridazin-3-yl which is optionally substituted in the 6-position by chlorine or methyl, or represents pyrazin-3-yl or represents 2-chloropyrazin-5-yl or represents 1,3-thiazol-5-yl which is optionally substituted in the 2-position by chlorine or methyl,
    R2 represents haloalkyl, haloalkenyl, halocycloalkyl or halocycloalkylalkyl.


Preferred substituents or ranges of the radicals listed in the formula (I-a) mentioned above and below are illustrated below.

    B preferably represents 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-methyl-pyrid-3-yl, 6-trifluoromethylpyrid-3-yl, 6-trifluoromethoxypyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl or 2-methyl-13′ thiazol-5-yl.
    R2 preferably represents fluorine-substituted C1-C5-alkyl, C2-C5-alkenyl, C3-C5-cycloalkyl or C3-C5-cycloalkylalkyl.
    B particularly preferably represents the radical 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl.
    R2 particularly preferably represents 2-fluoroethyl, 2,2-difluoroethyl, 2-fluorocyclopropyl.
    B very particularly preferably represents the radical 6-chloropyrid-3-yl.
    R2 very particularly preferably represents 2-fluoroethyl or 2,2-difluoroethyl.


In a prominent group of compounds of the formula (I-a). B represents 6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-a). B represents 6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-a), B represents 6-chloro-1,4-pyridazin-3-yl




In a further prominent group of compounds of the formula (I-a), R2 represents 2-fluoroethyl.
In a further prominent group of compounds of the formula (I-a). R2 represents 2,2-difluoroethyl.
A further preferred subgroup of the compounds of the formula (I) are those of the formula (I-b)




in which

    D represents a radical






in which

    X and Y have the meanings given above,
    R3 represents hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or alkoxy.


Preferred substituents or ranges of the radicals listed in the formula (I-b) mentioned above and below are illustrated below.

    D preferably represents one of the radicals 5,6-difluoropyrid-3-yl, 5-chloro-6-fluoropyrid-3-yl, 5-bromo-6-fluoropyrid-3-yl, 5-iodo-6-fluoropyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromopyrid-3-yl, 5-fluoro-6-iodopyrid-3-yl, 5-chloro-6-iodopyrid-3-yl, 5-bromo-6-iodopyrid-3-yl, 5-methyl-6-fluoropyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-bromopyrid-3-yl, 5-methyl-6-iodopyrid-3-yl, 5-difluoromethyl-6-fluoropyrid-3-yl, 5-difluoromethyl-6-chloropyrid-3-yl, 5-difluoromethyl-6-bromopyrid-3-yl, 5-difluoromethyl-6-iodopyrid-3-yl.
    R3 preferably represents C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl or C3-C4-cycloalkyl.
    D particularly preferably represents 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromopyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-chloro-6-iodopyrid-3-yl or 5-difluoromethyl-6-chloropyrid-3-yl.
    R3 particularly preferably represents C1-C4-alkyl.
    D very particularly preferably represents 5-fluoro-6-chloropyrid-3-yl or 5-fluoro-6-bromopyrid-3-yl
    R3 very particularly preferably represents methyl, ethyl, propyl vinyl, allyl, propargyl or cyclopropyl.
    D most preferably represents 5-fluoro-6-chloropyrid-3-yl.
    R3 most preferably represents methyl or cyclopropyl.


In a further prominent group of compounds of the formula (I-b). D represents 5-fluoro-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5,6-dichloropyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5-bromo-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5-methyl-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5-fluoro-6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5-chloro-6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-b), D represents 5-chloro-6-iodopyrid-3-yl




In a further prominent group of compounds of the formula (I-b), R3 represents ethyl.
In a further prominent group of compounds of the formula (I-b), R3 represents ethyl.
In a further prominent group of compounds of the formula (I-b), R3 represents cyclopropyl.
A further preferred subgroup of the compounds of the formula (I) are those of the formula (I-c)




in which

    represents a radical






in which

    X and Y have the meanings given above and
    R4 represents haloalkyl, haloalkenyl, halocycloalkyl or halocycloalkylalkyl.


Preferred substituents or ranges of the radicals listed in the formula (I-c) mentioned above and below are illustrated below.

    E preferably represents one of the radicals 5,6-difluoropyrid-3-yl, 5-chloro-6-fluoropyrid-3-yl, 5-bromo-6-fluoropyrid-3-yl, 5-iodo-6-fluoropyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-iodo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromopyrid-3-yl, 5-fluoro-6-iodopyrid-3-yl, 5-chloro-6-iodopyrid-3-yl, 5-bromo-6-iodopyrid-3-yl, 5-methyl-6-fluoropyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-methyl-6-bromopyrid-3-yl, 5-methyl-6-iodopyrid-3-yl, 5-difluoromethyl-6-fluoropyrid-3-yl, 5-difluoromethyl-6-chloropyrid-3-yl, 5-difluoromethyl-6-bromopyrid-3-yl, 5-difluoromethyl-6-iodopyrid-3-yl.
    R4 preferably represents fluorine-substituted C1-C5-alkyl, C2-C5-alkenyl, C3-C5-cycloalkyl or C3-C5-cycloalkylalkyl.
    E particularly preferably represents 2-chloropyrimidin-5-yl, 5-fluoro-6-chloropyrid-3-yl, 5,6-dichloropyrid-3-yl, 5-bromo-6-chloropyrid-3-yl, 5-fluoro-6-bromopyrid-3-yl, 5-chloro-6-bromopyrid-3-yl, 5,6-dibromopyrid-3-yl, 5-methyl-6-chloropyrid-3-yl, 5-chloro-6-iodopyrid-3-yl or 5-difluoromethyl-6-chloropyrid-3-yl.
    R4 particularly preferably represents 2-fluoroethyl, 2,2-difluoroethyl, 2-fluorocyclopropyl.
    E very particularly preferably represents 5-fluoro-6-chloropyrid-3-yl.
    R4 very particularly preferably represents 2-fluoroethyl or 2,2-difluoroethyl.


In a further prominent group of compounds of the formula (I-c), E represents 5-fluoro-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5,6-dichloropyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5-bromo-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5-methyl-6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5-fluoro-6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5-chloro-6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-c), E represents 5-chloro-6-iodopyrid-3-yl




In a further prominent group of compounds of the formula (I-c), R4 represents 2-fluoroethyl.
In a further prominent group of compounds of the formula (I-c), R4 represents 2,2-difluoroethyl.
A preferred subgroup of the compounds of the formula (I) are those of the formula (I-d)




in which

    G represents pyrid-2-yl or pyrid-4-yl, or represents pyrid-3-yl which is optionally substituted in the 6-position by fluorine, chlorine, bromine, methyl, trifluoromethyl or trifluoromethoxy, or represents pyridazin-3-yl which is optionally substituted in the 6-position by chlorine or methyl, or represents pyrazin-3-yl or represents 2-chloropyrazin-5-yl or represents 1,3-thiazol-5-yl which is optionally substituted in the 2-position by chlorine or methyl, and
    R5 represents C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C3-C4-cycloalkyl or C1-C4-alkoxy.


Preferred substituents or ranges of the radicals listed in the formula (I-d) mentioned above and below are illustrated below.

    G preferably represents 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-methyl-pyrid-3-yl, 6-trifluoromethylpyrid-3-yl, 6-trifluoromethoxypyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 6-methyl-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl or 2-methyl-1,3-thiazol-5-yl.
    R5 preferably represents C1-C4-alkyl, C1-alkoxy, C2-C4-alkenyl, C2-C4-alkynyl or C1-C4-cycloalkyl.
    G particularly preferably represents the radical 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 6-chloro-1,4-pyridazin-3-yl, 2-chloro-1,3-thiazol-5-yl,
    R5 particularly preferably represents methyl, methoxy, ethyl, propyl, vinyl, allyl, propargyl or cyclopropyl.
    G very particularly preferably represents the radical 6-chloropyrid-3-yl.
    R5 very particularly preferably represents methyl or cyclopropyl.


In a prominent group of compounds of the formula (I-d), G represents 6-chloropyrid-3-yl




In a further prominent group of compounds of the formula (I-d), G represents 6-bromopyrid-3-yl




In a further prominent group of compounds of the formula (I-d). G represents 6-chloro-1,4-pyridazin-3-yl




In a further prominent group of compounds of the formula (I-d), G represents 2-chloro-1,3-thiazol-5-yl




In a further prominent group of compounds of the formula (I-d), G represents 6-fluoropyrid-3-yl




In a further prominent group of compounds of the formula (I-d), G represents 6-trifluoromethyl-pyrid-3-yl




In a further prominent group of compounds of the formula (I-d), G represents 6-fluoropyrid-3-yl




In a further prominent group of compounds of the formula (I-d), R5 represents methyl.
In a further prominent group of compounds of the formula (I-d). R5 represents cyclopropyl.
Specific mention may be made of the following compounds of the general formula (I):

    
    
        Compound (I-1), 4-{[(6-bromopyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known the international patent application WO 2007/115644.
        Compound (I-2), 4-{[(6-fluoropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115644.
        Compound (I-3), 4-{[(2-chloro-1,3-thiazol-5-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115644.
        Compound (1-4), 4-{[(6-chloropyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115644.
        Compound (I-5), 4-{[(6-chloropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115644.
        Compound (I-6), 4-{[(6-chloro-5-fluoropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115643.
        Compound (I-7), 4-{[(5,6-dichloropyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115646.
        Compound (I-8), 4-{[(6-chloro-5-fluoropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from the international patent application WO 2007/115643.
        Compound (I-9), 4-{[(6-chloropyrid-3-yl)methyl](cyclopropyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from EP 0 539 588.
        Compound (I-10), 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one, has the formula
    
    






    
    
        and is known from EP 0 539 588.
    
    


Preference is given to compounds of the formula (I) selected from the group consisting of the compounds of the formulae (I-a), (I-b), (I-c) and (I-d) mentioned above.
Preference is furthermore given to compounds of the formula (I) selected from the group consisting of the compounds of the formulae (I-a), (I-b) and (I-c) mentioned above.
Particular preference is given to compounds of the formula (I) in which A is selected from the radicals 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 2-chloro-1,3-thiazol-5-yl and 5,6-dichloropyrid-3-yl and R1 is selected from the radicals methyl, cyclopropyl, methoxy, 2-fluoroethyl or 2,2-difluoroethyl.
Very particular preference is given to compounds of the formula (I) selected from the group consisting of the compounds of the formulae (I-1), (I-2), (I-3), (I-4), (I-5), (I-6), (I-7), (I-8), (I-9) and (I-10).
According to the invention. “alkyl” represents straight-chain or branched aliphatic hydrocarbons having 1 to 6, preferably 1 to 4, carbon atoms. Suitable alkyl groups are, for example, methyl, ethyl, n-propyl, i-propyl, n-, iso-, sec- or tert-butyl, pentyl or hexyl. The alkyl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “alkenyl” represents straight-chain or branched hydrocarbons having at least one double bond. The double bond of the alkenyl group may be unconjugated or is conjugated to an unsaturated bond or group. Alkenyl groups having 2 to 6 or 3 to 6 carbon atoms are preferred. Suitable alkenyl groups are, for example, vinyl or allyl. The alkenyl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “alkynyl” represents straight-chain or branched hydrocarbons having at least one triple bond. The triple bond of the alkynyl group may be unconjugated or is conjugated to an unsaturated bond or group. Alkynyl groups having 2 to 6 or 3 to 6 carbon atoms are preferred. Suitable alkynyl groups are, for example, ethynyl, propynyl, butynyl, pentynyl, hexynyl, methylpropynyl, 4-methyl-1-butynyl, 4-propyl-2-pentynyl and 4-butyl-2-hexynyl. The alkynyl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “cycloalkyl” represents cyclic hydrocarbons having 3 to 6 carbon atoms. Suitable cycloalkyl groups are, for example, cyclopropyl cyclobutyl, cyclopentyl or cyclohexyl. The cycloalkyl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “alkoxy” represents alkoxy groups having 1 to 6 carbon atoms, preferably having 1 to 4 carbon atoms. Suitable alkoxy groups are, for example, methyloxy, ethyloxy, n-propyloxy, i-propyloxy, n-, iso-, sec- or tert-butyloxy, pentyloxy or hexyloxy. The alkoxy group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “alkylamino” represents alkylamino groups having 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms. Suitable alkylamino groups are, for example, methylamino, ethylamino, n-propylamino, i-propylamino, n-, iso-, sec- or tert-butylamino, pentylamino or hexylamino. The alkylamino group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “heterocyclic compounds” represents cyclic hydrocarbons having preferably 3 to 14, particularly preferably 3 to 10 and very particularly preferably 5 to 6 carbon atoms which contain at least one heteroatom, such as, for example, nitrogen, oxygen or sulphur and which can be prepared by customary methods. The heterocyclic compounds may contain saturated and unsaturated bonds or groups which are additionally in conjugation with further unsaturated bonds or groups, Suitable heterocyclic compounds are, for example, oxirane, aziridine, azetidine, tetrahydrofuran, dioxane, tetrahydrofuran-2-one, caprolactam: unsaturated heterocyclic compounds, such as, for example, 2H-pyrrole, 4H-pyran, 1,4-dihydropyridine: and heteroaryls, such as, for example, pyrrole, pyrrazole, imidazole, oxazole, isoxazole, thiazole, oxathiazole, triazole, tetrazole, pyridine, pyridazine, pyrimidine, pyrazine, purine, pteridine, quinoline, isoquinoline, acridine and phenazine. The heterocyclic compounds may be unsubstituted or are substituted by at least one of the substituents mentioned here.
According to the invention, “halogen” represents fluorine, chlorine, bromine or iodine, preferably fluorine, chlorine or bromine.
According to the invention, “haloalkyl” represents alkyl groups having 1 to 6, preferably 1 to 4, carbon atoms in which at least one hydrogen atom has been replaced by a halogen. Suitable haloalkyl groups are, for example, CH2F, CHF2, CF3, CF2Cl, CFCl2, CCl3, CF2Br, CF2CF3, CFHCF3, CH2CF3, CH2CH2F, CH2CHF2, CFClCF3, CCl2CF3, CF2CH3, CF2CH2F, CF2CHF2, CF2CF2Cl, CF2CF2Br, CFHCH3, CFHCHF2, CHFCF3, CHFCF2Cl, CHFCF2Br, CFClCF3, CCl2CF3, CF2CF2CF3, CH2CH2CH2F, CH2CHFCH3, CH2CF2CF3, CF2CH2CF3, CF2CF2CH3, CHFCF2CF3, CF2CHFCF3, CF2CF2CHF2, CF2CF2CH2F, CF2CF2CF2Cl, CF2CF2CF2Br, 1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl, pentafluoroethyl, 1-(difluoromethyl)-1,2,2,2-tetrafluoroethyl, 2-bromo-1,2,2-trifluoro-1-(trifluoromethyl)ethyl, 1-(difluoromethyl)-2,2,2-trifluoroethyl. The haloalkyl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
According to the invention, “aryl” represents aryl groups having 6 to 10, preferably 6, carbon atoms. Suitable aryl groups are, for example, phenyl or naphthyl. The aryl group may be unsubstituted or is substituted by at least one of the substituents mentioned here.
Preference is given to mixtures of two or more, preferably two or three, particularly preferably two, of the insecticidally active compounds.
According to the method proposed according to the invention, transgenic plants, in particular useful plants, are treated with compounds of the formula (I) to increase agricultural productivity. For the purpose of the invention, transgenic plants are plants which contain at least one gene or gene fragment which is not the result of fertilization. This gene or gene fragment may originate or be derived from another plant of the same species, from plants of a different species, but also from organisms from the animal kingdom or microorganisms (including viruses) (“foreign gene”) and/or, if appropriate, already have mutations compared to the naturally occurring sequence. According to the invention, it is also possible to use synthetic genes, this also being included in the term “foreign gene” here. It is also possible for a transgenic plant to code for two or more foreign genes of different origin.
For the purpose of the invention, the “foreign gene” is further characterized in that it comprises a nucleic acid sequence which has a certain biological or chemical function or activity in the transgenic plant. In general, these genes code for biocatalysts, such as, for example, enzymes or ribozymes, or else they comprise regulatory sequences, such as, for example, promoters or terminators, for controlling the expression of endogenous proteins. However, to this end, they may also code for regulatory proteins, such as, for example, repressors or inductors. Furthermore, the foreign gene may also serve the targeted localization of a gene product of the transgenic plant, coding, for example, for a signal peptide. The foreign gene may also code for inhibitors, such as, for example, antisense RNA.
The person skilled in the art is readily familiar with numerous different methods for producing transgenic plants and methods for the targeted mutagenesis, for gene transformation and cloning, for example from: Willmitzer, 1993, Transgenic plants, in: Biotechnology, A Multivolume Comprehensive Treatise, Rehm et al. (eds.), Vol. 2, 627-659, VCH Weinheim, Germany.
A good example of a complex genetic manipulation of a useful plant is the so-called GURT technology (“Genetic Use Restriction Technologies”) which allows the technical control of the propagation of the transgenic plant variety in question. To this end, in general two or three foreign genes are cloned into the useful plant which, in a complex interaction after administration of an external stimulus, trigger a cascade resulting in the death of the embryo which would otherwise develop. To this end, the external stimulus (for example an active compound or another chemical or abiotic stimulus) may interact, for example, with a repressor which then no longer suppresses the expression of a recombinase, so that the recombinase is able to cleave an inhibitor thus allowing expression of a toxin causing the embryo to die. Examples of this type of transgenic plant are disclosed in U.S. Pat. No. 5,723,765 or U.S. Pat. No. 5,808,034.
Accordingly, the person skilled in the art is familiar with processes for generating transgenic plants which, by virtue of the integration of regulatory foreign genes and the overexpression, suppression or inhibition of endogenous genes or gene sequences mediated in this manner, if appropriate, or by virtue of the existence or expression of foreign genes or fragments thereof, have modified properties.
As already discussed above the method according to the invention allows better utilization of the production potential of transgenic plants. On the one hand, this may, if appropriate, be based on the fact that the application rate of the active compound which can be employed according to the invention can be reduced, for example by lowering the dose employed or else by reducing the number of applications. On the other hand, if appropriate, the yield of the useful plants may be increased quantitatively and/or qualitatively. This is true in particular in the case of a transgenically generated resistance to biotic or abiotic stress. If, for example, compounds of the formula (I) are employed, it may in certain cases be possible to limit the dosage of the insecticide to a sublethal dose without significantly reducing the desired effect of the active compound on the pests.
Depending on the plant species or plant varieties, their location and the growth conditions (soils, climate, vegetation period, nutrients), these synergistic actions may vary and may be multifarious. Thus possible are, for example, reduced application rates and/or a widening of the activity spectrum and/or an increase of the activity of the compounds and compositions used according to the invention, better plant growth, increased tolerance to high or low temperatures, increased tolerance to drought or to water or soil salt content, increased flowering, easier harvesting, accelerated maturation, higher harvest yields, higher quality and/or higher nutrient value of the harvested products, increased storability and/or processibility of the harvested products, which exceed the effects normally to be expected.
These advantages are the result of a synergistic action, achieved according to the invention, between the compounds of the formula (I) which can be employed and the respective principle of action of the genetic modification of the transgenic plant. This reduction of production means as a result of the synergism, with simultaneous yield or quality increase, is associated with considerable economical and ecological advantages.
A list of examples known to the person skilled in the art of transgenic plants, with the respective affected structure in the plant or the protein expressed by the genetic modification in the plant being mentioned, is compiled in Table 1. Here, the structure in question or the principle expressed is in each case grouped with a certain feature in the sense of a tolerance to a certain stress factor. A similar list (Table 3) compiles—in a slightly different arrangement—likewise examples of principles of action, tolerances induced thereby and possible useful plants. Further examples of transgenic plants suitable for the treatment according to the invention are compiled in Table 4.
In an advantageous embodiment, the compounds of the formula (I) are used for treating transgenic plants comprising at least one gene or gene fragment coding for a Bt toxin. A Bt toxin is a protein originating from or derived from the soil bacterium Bacillus thuringiensis which either belongs to the group of the crystal toxins (Cry) or the cytolytic toxins (Cyt). In the bacterium, they are originally formed as protoxins and are only metabolized in alkaline medium—for example in the digestive tract of certain feed insects—to their active form. There, the active toxin then binds to certain hydrocarbon structures at cell surfaces causing pores to be formed which destroy the osmotic potential of the cell, which may effect cell lysis. The result is the death of the insects. Bt toxins are active in particular against certain harmful species from the orders of the Lepidoptera (butterflies), Homoptera, Diptera and Coleoptera (beetles) in all their development stages; i.e. from the egg larva via their juvenile forms to their adult forms.
It has been known for a long time that gene sequences coding for Bt toxins, parts thereof or else peptides or proteins derived from Bt toxins can be cloned with the aid of genetic engineering into agriculturally useful plants to generate transgenic plants having endogenous resistance to pests sensitive to Bt toxins. For the purpose of the invention, the transgenic plants coding for at least one Bt toxin or proteins derived therefrom are defined as “Bt plants”.
The “first generation” of such Bt plants generally only comprise the genes enabling the formation of a certain toxin, thus only providing resistance to one group of pathogens. An example of a commercially available maize variety comprising the gene for forming the Cry1Ab toxin is “YieldGard®” from Monsanto which is resistant to the European corn borer. In contrast, in the Bt cotton variety (Bollgard®), resistance to other pathogens from the family of the Lepidoptera is generated by introduction by cloning of the genes for forming the Cry1Ac toxin. Other transgenic crop plants, in turn, express genes for forming Bt toxins with activity against pathogens from the order of the Coleoptera. Examples that may be mentioned are the Bt potato variety “NewLeaf®” (Monsanto) capable of forming the Cry3A toxin, which is thus resistant to the Colorado potato beetle, and the transgenic maize variety “YieldGard®” (Monsanto) which is capable of forming the Cry 3Bb1 toxin and is thus protected against various species of the Western corn rootworm.
In a “second generation”, the multiply transgenic plants, already described above, expressing or comprising at least two foreign genes were generated.
Preference according to the invention is given to transgenic plants with Bt toxins from the group of the Cry family (see, for example, Crickmore et al., 1998, Microbiol. Mol. Biol. Rev. 62: 807-812), which are particularly effective against Lepidoptera, Coleoptera and Diptera. Examples of genes coding for the proteins are:
cry1Aa1, cry1Aa2, cry1Aa3, cry1Aa4, cry1Aa5, cry1Aa6, cry1Aa7, cry1Aa8, cry1Aa9, cry1Aa10, cry1Aa11, cry1Ab1, cry1Ab2, cry1Ab3, cry1Ab4, cry1Ab5, cry1Ab6, cry1Ab7, cry1Ab8, cry1Ab9, cry1Ab10, cry1Ab11, cry1Ab12, cry1Ab13, cry1Ab14, cry1Ac1, cry1Ac2, cry1Ac3, cry1Ac4, cry1Ac5, cry1Ac6, cry1Ac7, cry1Ac8, cry1Ac9, cry1Ac10, cry1Ac11, cry1Ac12, cry1Ac13, cry1Ad1, cry1Ad2, cry1Ae1, cry1Af1, cry1Ag1, cry1Ba1, cry1Ba2, cry1Bb1, cry1Bc1, cry1Bd1, cry1Be1, cry1Ca1, cry1Ca2, cry1Ca3, cry1Ca4, cry1Ca5, cry1Ca6, cry1Ca7, cry1Cb1, cry1Cb2, cry1Da1, cry1Da2 cry1Db1, cry1Ea1, cry1Ea2, cry1Ea3, cry1Ea4, cry1Ea5, cry1Ea6, cry1Eb1, cry1Fa1, cry1Fa2, cry1Fb1, cry1Fb2, cry1Fb3, cry1Fb4, cry1Ga1, cry1Ga2, cry1Gb1, cry1Gb2, cry1Ha1, cry1Hb1, cry1Ia1, cry1Ia2, cry1Ia3, cry1Ia4, cry1Ia5, cry1Ia6, cry1Ib1, cry1Ic1, cry1Id1, cry1Ie1, cry1I-like, cry1Ja1, cry1Jb1, cry1Jc1, cry1Ka1, cry1-like, cry2Aa1, cry2Aa2, cry2Aa3, cry2Aa4, cry2Aa5, cry2Aa6, cry2Aa7, cry2Aa8, cry2Aa9, cry2Ab1, cry2Ab2, cry2Ab3, cry2Ac1, cry2Ac2, cry2Ad1, cry3Aa1, cry3Aa2, cry3Aa3, cry3Aa4, cry3Aa5, cry3Aa6, cry3Aa7, cry3Ba1, cry3Ba2, cry3Bb1, cry3Bb2, cry3Bb3, cry3Ca1, cry4Aa1, cry4Aa2, cry4Ba1, cry4Ba2, cry4Ba3, cry4Ba4, cry5Aa1, cry5Ab1, cry5Ac1, cry5Ba1, cry6Aa1, cry6Ba1, cry7Aa1, cry7Ab1, cry7Ab2, cry8Aa1, cry8Ba1, cry8Ca1, cry9Aa1, cry9Aa2, cry9Ba1, cry9Ca1, cry9Da1, cry9Da2, cry9Ea1, cry9 like, cry10Aa1, cry10Aa2, cry11Aa1, cry11Aa2, cry11Ba1, cry11Bb1, cry12Aa1, cry13Aa1, cry14Aa1, cry15Aa1, cry16Aa1, cry17Aa1, cry18Aa1, cry18Ba1, cry18Ca1, cry19Aa1, cry19Ba1, cry20Aa1, cry21Aa1, cry21Aa2, cry22Aa1, cry23Aa1, cry24Aa1, cry25Aa1, cry26Aa1, cry27Aa1, cry28Aa1, cry28Aa2, cry29Aa1, cry30Aa1, cry31Aa1, cyt1Aa1, cyt1Aa2, cyt1Aa3, cyt1Aa4, cyt1Ab1, cyt1Ba1, cyt2Aa1, cyt2Ba1, cyt2Ba2, cyt2Ba3, cyt2Ba4, cyt2Ba5, cyt2Ba6, cyt2Ba7, cyt2Ba8, cyt2Bb1.
Particular preference is given to the genes or gene sections of the subfamilies cry1, cry2, cry3, cry5 and cry9; especially preferred are cry1Ab, cry1Ac, cry3A, cry3B and cry9C.
Furthermore, it is preferred to use plants which, in addition to the genes for one or more Bt toxins, express or contain, if appropriate, also genes for expressing, for example, a protease or peptidase inhibitor (such as in WO-A 95/35031), of herbicide resistances (for example to glufosinate or glyphosate by expression of the pat gene or bar gene) or for becoming resistant to nematodes, fungi or viruses (for example by expressing a gluconase, chitinase). However, they may also be genetically modified in their metabolic properties, so that they show a qualitative and/or quantitative change of ingredients (for example by modification of the energy, carbohydrate, fatty acid or nitrogen metabolism or by metabolite currents influencing these (see above).
A list of examples of principles of action which can be introduced by genetic modification into a useful plant and which are suitable for the treatment according to the invention on their own or in combination is compiled in Table 2. Under the header “AP” (active principle), this table contains the respective principle of action and associated therewith the pest to be controlled.
In a particularly preferred variant, the process according to the invention is used for treating transgenic vegetable, maize, soya bean, cotton, tobacco, rice, potato and sugar beet varieties. These are preferably Bt plants.
The vegetable plants or varieties are, for example, the following useful plants:

    
    
        potatoes: preferably starch potatoes, sweet potatoes and table potatoes;
        root vegetables: preferably carrots, turnips (swedes, stubble turnips (Brassica rapa var. rapa), spring turnips, autumn turnips (Brassica campestris ssp. rapifera). Brassica rapa L. ssp. rapa f. teltowiensis), scorzonera, Jerusalem artichoke, turnip-rooted parsley, parsnip, radish and horseradish;
        a tuber vegetables: preferably kohlrabi, beetroot, celeriac, garden radish;
        bulb crops: preferably scallion, leek and onions (planting onions and seed onions);
        brassica vegetables: preferably headed cabbage (white cabbage, red cabbage, kale, savoy cabbage), cauliflowers, broccoli, curly kale, marrow-stem kale, seakale and Brussels sprouts;
        fruiting vegetables: preferably tomatoes (outdoor tomatoes, vine-ripened tomatoes, beef tomatoes, greenhouse tomatoes, cocktail tomatoes, industrial and fresh market tomatoes), melons, eggplants, aubergines, pepper (sweet pepper and hot pepper. Spanish pepper), chilli pepper, pumpkins, courgettes and cucumbers (outdoor cucumbers, greenhouse cucumbers snake gourds and gherkins);
        vegetable pulses: preferably bush beans (as sword beans, string beans, flageolet beans, wax beans, corn beans of green- and yellow-podded cultivars), pole beans (as sword beans, string beans, flageolet beans, wax beans of green-, blue- and yellow-podded cultivars), broadbeans (field beans, Windsor beans, cultivars having white- and black-spotted flowers), peas (chickling vetch, chickpeas, marrow peas, shelling peas, sugar-peas, smooth peas, cultivars having light- and dark-green fresh fruits) and lentils;
        a green vegetables and stem vegetables: preferably Chinese cabbage, round-headed garden lettuce, curled lettuce, lamb's-lettuce, iceberg lettuce, romaine lettuce, oakleaf lettuce, endives, radicchio, lollo rossa, ruccola lettuce, chicory, spinach, chard (leaf chard and stem chard) and parsley;
        a other vegetables: preferably asparagus, rhubarb, chives, artichokes, mint varieties, sunflowers. Florence fennel dill, garden cress, mustard poppy seed, peanuts, sesame and salad chicory.
    
    


Bt vegetables including exemplary methods for preparing them are described in detail, for example, in Barton et al., 1987, Plant Physiol. 85: 1103-09; Vaeck et al., 1987, Nature 328: 33-37: Fischhoff et al. 1987. Bio/Technology 5: 807-813. In addition. Bt vegetable plants are already known as commercial varieties, for example the potato cultivar NewLeaf® (Monsanto). The preparation of Bt vegetables is also described in U.S. Pat. No. 6,072,105.
Likewise, Bt cotton is already known in principle, for example from U.S. Pat. No. 5,322,938. In the context of the present invention, particular preference is given to Bt cotton with the trade names NuCOTN33® and NuCOTN33B®.
The use and preparation of Bt maize has likewise already been known for a long time, for example from Ishida, Y., Saito. H., Ohta, S., Hiei, Y., Komari, T., and Kumashiro, T. (1996). High efficiency transformation of maize (Zea mayz L.) mediated by Agrobacterium tumefaciens, Nature Biotechnology 4: 745-750. EP-B-0485506, too, describes the preparation of Bt maize plants. Furthermore, different varieties of Bt maize are commercially available, for example under the following names (company/companies is/are in each case given in brackets): KnockOut® (Novartis Seeds). NaturGard® (Mycogen Seeds), Yieldgard® (Novartis Seeds, Monsanto, Cargill, Golden Harvest, Pioneer, DeKalb inter alia), Bt-Xtra® (DeKalb) and StarLink® (Aventis CropScience, Garst inter alia). For the purpose of the present invention, particular preference is given especially to the following maize cultivars: KnockOut®, NaturGard®, Yieldgard®, Bt-Xtra® and StarLink®.
For soya beans, too. Roundup®Ready cultivar or cultivars resistant to the herbicide Liberty Link® are available and can be treated according to the invention. In the case of rice, a large number of “Golden Rice” lines are available which are likewise characterized in that, by virtue of a transgenic modification, they have an increased content of provitamin A. They, too, are examples of plants which can be treated by the method according to the invention, with the advantages described.
The method according to the invention is suitable for controlling a large number of harmful organisms which occur in particular in vegetables, maize and cotton, in particular insects and arachnids, very particularly preferably insects. The pests mentioned include:

    
    
        From the order of the Anoplura (Phthiraptera), for example. Damalinia spp., Haematopinus spp., Linognathus spp., Pediculus spp., Trichodectes spp.
        From the class of the Arachnida, for example. Acarus siro, Aceria sheldoni, Aculops spp., Aculus spp., Amblyomma spp., Argas spp., Boophilus spp., Brevipalpus spp., Bryobia praetiosa, Chorioptes spp., Dermanyssus gallinae, Eotetranychus spp. Epitrimerus pyri, Eutetranychus spp. Eriophyes spp., Hemitarsonemus spp., Hyalomma spp., Ixodes spp. Latrodectus mactans, Metatetranychus spp., Oligonychus spp., Ornithodoros spp., Panonychus spp., Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus spp., Sarcoptes spp., Scorpio maurus, Stenotarsonemus spp. Tarsonemus spp., Tetranychus spp. Vasates lycopersici. 
        From the class of the Bivalva, for example, Dreissena spp.
        From the order of the Chilopoda, for example, Geophilus spp., Scutigera spp.
        From the order of the Coleoptera, for example, Acanthoscelides obtectus, Adoretus spp., Agelastica alni, Agriotes spp., Amphimallon solstitialis, Anobium punctatum, Anoplophora spp., Anthonomus spp., Anthrenus spp., Apogonia spp., Atomaria spp., Attagenus spp., Bruchidius obtectus. Bruchus spp., Ceuthorhynchus spp., Cleonus mendicus, Conoderus spp., Cosmopolites spp., Costelytra zealandica, Curculio spp., Cryptorhynchus lapathi, Dermestes spp., Diabrotica spp., Epilachna spp., Faustinus cubae, Gibbium psylloides, Heteronychus arator. Hylamorpha elegans, Hylotrupes bajulus, Hypera postica, Hypothenemus spp., Lachnosterna consanguinea, Leptinotarsa decemlineata, Lissorhoptrus oryzophilus, Lixus spp., Lyctus spp., Meligethes aeneus, Melolontha melolontha, Migdolus spp., Monochamus spp., Naupactus xanthographus, Niptus hololeucus, Oryctes rhinoceros, Oryzaephilus surinamensis, Otiorrhynchus sulcatus, Oxycetonia jucunda, Phaedon cochleariae, Phyllophaga spp., Popillia japonica, Premnotrypes spp., Psylliodes chrysocephala, Ptinus spp., Rhizobius ventralis, Rhizopertha dominica, Sitophilus spp., Sphenophorus spp., Sternechus spp., Symphyletes spp., Tenebrio molitor, Tribolium spp., Trogodemma spp., Tychius spp., Xylotrechus spp., Zabrus spp.
        From the order of the Collembola, for example, Onychiurus armatus. 
        From the order of the Dermaptera, for example, Forficula auricularia. 
        From the order of the Diplopoda, for example, Blaniulus guttulatus. 
        From the order of the Diptera, for example, Aedes spp., Anopheles spp., Bibio hortulanus, Calliphora erythrocephala, Ceratitis capitata, Chrysomyia spp. Cochliomyia spp., Cordylobia anthropophaga, Culex spp. Cuterebra spp., Dacus oleae, Dermatobia hominis, Drosophila spp., Fannia spp., Gastrophilus spp., Hylemyia spp., Hyppobosca spp. Hypoderma spp., Liriomyza spp. Lucilia spp., Musca spp., Nezara spp., Oestrus spp., Oscinella frit, Pegomyia hyoscyami, Phorbia spp., Stomoxys spp., Tabanus spp., Tannia spp., Tipula paludosa, Wohlfahrtia spp.
        From the class of the Gastropoda, for example, Arion spp., Biomphalaria spp., Bulinus spp., Deroceras spp., Galba spp., Lymnaea spp., Oncomelania spp., Succinea spp.,
        From the class of the helminths, for example. Ancylostoma duodenale, Ancylostoma ceylanicum, Acylostoma braziliensis, Ancylostoma spp., Ascaris lubricoides, Ascaris spp., Brugia malayi, Brugia timori, Bunostomum spp., Chabertia spp., Clonorchis spp. Cooperia spp., Dicrocoelium spp, Dictyocaulus filaria, Diphyllobothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp., Haemonchus spp. Heterakis spp., Hymenolepis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesophagostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp. Paragonimus spp., Schistosomen spp, Strongyloides fuelleborni, Strongyloides stercoralis, Stronyloides spp., Taenia saginata, Taenia solium, Trichinella spiralis, Trichinella nativa, Trichinella britovi, Trichinella nelsoni, Trichinella pseudopsiralis, Trichostrongulus spp., Trichuris trichuria, Wuchereria bancrofti. 
        It is furthermore possible to control Protozoa, such as Eimeria. 
        From the order of the Heteroptera, for example, Anasa tristis, Antestiopsis spp., Blissus spp., Calocoris spp., Campylomma livida, Cavelerius spp., Cimex spp., Creontiades dilutus, Dasynus piperis, Dichelops furcatus, Diconocoris hewetti, Dysdercus spp., Euschistus spp., Eurygasteri spp., Heliopeltis spp., Horcias nobilellus, Leptocorisa spp., Leptoglossus phyllopus, Lygus spp., Macropes excavatus, Miridae, Nezara spp., Oebalus spp., Pentomidae, Piesma quadrata, Piezodorus spp., Psallus seriatus, Pseudacysta persea, Rhodnius spp., Sahlbergella singularis, Scotinophora spp., Stephanitis nashi, Tibraca spp., Triatoma spp.
        From the order of the Homoptera, for example. Acyrthosipon spp., Aeneolamia spp., Agonoscena spp., Aleurodes spp., Aleurolobus barodensis, Aleurothrixus spp., Amrasca spp., Anuraphis cardui, Aonidiella spp., Aphanostigma piri, Aphis spp., Arboridia apicalis, Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacorthum solani, Bemisia spp., Brachycaudus helichrysii, Brachycolus spp., Brevicoryne brassicae, Calligypona marginata, Carneocephala fulgida, Ceratovacuna lanigera, Cercopidae, Ceroplastes spp. Chaetosiphon fragaefolii, Chionaspis tegalensis, Chlorita onukii, Chromaphis juglandicola, Chrysomphalus ficus, Cicadulina mbila, Coccomytilus bulli, Coccus spp., Cryptomyzus ribis, Dalbulus spp., Dialeurodes spp., Diaphorina spp., Diaspis spp., Doralis spp., Drosicha spp., Dysaphis spp., Dysmicoccus spp., Empoasca spp., Eriosoma spp., Erythroneura spp., Euscelis bilobatus, Geococcus coffeae, Homalodisca coagulate, Hyalopterus arundinis, Icerya spp., Idiocerus spp. Idioscopus spp., Laodelphax striatellus, Lecanium spp., Lepidosaphes spp., Lipaphis erysimi, Macrosiphum spp., Mahanarva fimbriolata, Melanaphis sacchari, Metcalfiella spp. Metopolophium dirhodum, Monellia costalis, Monelliopsis pecanis, Myzus spp., Nasonovia ribisnigri, Nephotettix spp., Nilaparvata lugens, Oncometopia spp., Orthezia praelonga, Parabemisia myricae, Paratrioza spp., Parlatoria spp., Pemphigus spp., Peregrinus maidis, Phenacoccus spp., Phloeomyzus passerinii, Phorodon humuli, Phylloxera spp., Pinnaspis aspidistrae, Planococcus spp., Protopulvinaria pyriformis, Pseudaulacaspis pentagona, Pseudococcus spp., Psylla spp., Pteromalus spp., Pyrilla spp., Quadraspidiotus spp., Quesada gigas, Rastrococcus spp., Rhopalosiphum spp., Saissetia spp., Scaphoides titanus, Schizaphis graminum, Selenaspidus articulatus, Sogata spp., Sogatella furcifera, Sogatodes spp., Stictocephala festina, Tenalaphara malayensis, Tinocallis caryaefoliae, Tomaspis spp., Toxoptera spp., Trialeurodes vaporariorum, Trioza spp., Typhlocyba spp., Unaspis spp., Viteus vitifolii. 
        From the order of the Hymenoptera, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis, Vespa spp.
        From the order of the Isopoda, for example, Armadillidium vulgare, Oniscus asellus, Porcellio scaber. 
        From the order of the Isoptera, for example, Reticulitermes spp. Odontotermes spp.
        From the order of the Lepidoptera, for example, Acronicta major, Aedia leucomelas, Agrotis spp., Alabama argillacea, Anticarsia spp., Barathra brassicae, Bucculatrix thurberiella, Bupalus piniarius, Cacoecia podana, Capua reticulana, Carpocapsa pomonella, Chematobia brumata, Chilo spp., Choristoneura fumiferana, Clysia ambiguella, Cnaphalocerus spp., Earias insulana, Ephestia kuehniella, Euproctis chrysorrhoea, Euxoa spp., Feltia spp., Galleria mellonella, Helicoverpa spp., Heliothis spp., Hofmannophila pseudospretella, Homona magnanima, Hyponomeuta padella, Laphygma spp., Lithocolletis blancardella, Lithophane antennata, Loxagrotis albicosta, Lymantria spp., Malacosoma neustria, Mamestra brassicae, Mocis repanda, Mythimna separata, Oria spp., Oulema oryzae, Panolis flammea, Pectinophora gossypiella, Phyllocnistis citrella, Pieris spp. Plutella xylostella, Prodenia spp. Pseudaletia spp., Pseudoplusia includens, Pyrausta nubilalis, Spodoptera spp., Thermesia gemmatalis, Tinea pellionella, Tineola bisselliella, Tortrix viridana, Trichoplusia spp.
        From the order of the Orthoptera, for example, Acheta domesticus, Blatta orientalis, Blattella germanica, Gryllotalpa spp., Leucophaea maderae, Locusta spp., Melanoplus spp., Periplaneta americana, Schistocerca gregaria. 
        From the order of the Siphonaptera, for example, Ceratophyllus spp., Xenopsylla cheopis. 
        From the order of the Symphyla, for example, Scutigerella immaculata. 
        From the order of the Thysanoptera, for example, Baliothrips biformis, Enneothrips flavens, Frankliniella spp., Heliothrips spp., Hercinothrips femoralis, Kakothrips spp., Rhipiphorothrips cruentatus, Scirtothrips spp., Taeniothrips cardamoni, Thrips spp.
        From the order of the Thysanura, for example, Lepisma saccharina. 
        The phytoparasitic nematodes include, for example, Anguina spp., Aphelenchoides spp., Belonoaimus spp., Bursaphelenchus spp., Ditylenchus dipsaci, Globodera spp., Heliocotylenchus spp., Heterodera spp., Longidorus spp., Meloidogyne spp., Pratylenchus spp., Radopholus similis, Rotylenchus spp., Trichodorus spp., Tylenchorhynchus spp., Tylenchulus spp., Tylenchulus semipenetrans, Xiphinema spp.
    
    


The method according to the invention for the treatment of Bt vegetables, Bt maize. Bt cotton, Bt soya beans, Bt tobacco and also Bt rice, Bt sugar beets or Bt potatoes is particularly suitable for controlling aphids (Aphidina), whiteflies (Trialeurodes), thrips (Thysanoptera), spider mites (Arachnida), soft scale insects or mealy bugs (Coccoidae and Pseudococcoidae, respectively).
The active compounds which can be used according to the invention can be employed in customary formulations, such as solutions, emulsions, wettable powders, water- and oil-based suspensions, powders, dusts, pastes, soluble powders, soluble granules, granules for broadcasting, suspoemulsion concentrates, natural compounds impregnated with active compound, synthetic substances impregnated with active compound, fertilizers and also microencapsulations in polymeric substances.
These formulations are prepared in a known manner, for example by mixing the active compounds with extenders, i.e. liquid solvents and/or solid carriers, if appropriate using surfactants, i.e. emulsifiers and/or dispersants and/or foam-formers. The formulations are prepared either in suitable plants or else before or during application.
Wettable powders are preparations which can be dispersed homogeneously in water and which, in addition to the active compound and beside a diluent or inert substance, also comprise wetting agents, for example polyethoxylated alkylphenols, polyethoxylated fatty alcohols, alkylsulphonates or alkylphenylsulphonates and dispersants, for example sodium lignosulphonate, sodium 2,2′-dinaphthylmethane-6,6′-disulphonate.
Dusts are obtained by grinding the active compound with finely distributed solid substances, for example talc, natural clays, such as kaolin, bentonite, pyrophillite or diatomaceous earth. Granules can be prepared either by spraying the active compound onto granular inert material capable of adsorption or by applying active compound concentrates to the surface of carrier substances, such as sand, kaolinites or granular inert material, by means of adhesives, for example polyvinyl alcohol, sodium polyacrylate or mineral oils. Suitable active compounds can also be granulated in the manner customary for the preparation of fertilizer granules—if desired as a mixture with fertilizers.
Suitable for use as auxiliaries are substances which are suitable for imparting to the composition itself and/or to preparations derived therefrom (for example spray liquors, seed dressings) particular properties such as certain technical properties and/or also particular biological properties. Typical suitable auxiliaries are: extenders, solvents and carriers.
Suitable extenders are, for example, water, polar and nonpolar organic chemical liquids, for example from the classes of the aromatic and non-aromatic hydrocarbons (such as paraffins, alkylbenzenes, alkylnaphthalenes, chlorobenzenes), the alcohols and polyols (which, if appropriate, may also be substituted, etherified and/or esterified), the ketones (such as acetone, cyclohexanone), esters (including fats and oils) and (poly)ethers, the unsubstituted and substituted amines, amides, lactams (such as N-alkylpyrrolidones) and lactones, the sulphones and sulphoxides (such as dimethyl sulphoxide).
If the extender used is water, it is also possible to employ, for example, organic solvents as auxiliary solvents. Essentially, suitable liquid solvents are: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics and chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons such as cyclohexane or paraffins, for example petroleum fractions, mineral and vegetable oils, alcohols such as butanol or glycol and also their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, strongly polar solvents such as dimethyl sulphoxide, and also water.
Suitable solid carriers are:
for example, ammonium salts and ground natural minerals such as kaolins, clays, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals, such as finely divided silica, alumina and silicates; suitable solid carriers for granules are: for example, crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, and also synthetic granules of inorganic and organic meals, and granules of organic material such as paper sawdust, coconut shells, maize cobs and tobacco stalks; suitable emulsifiers and/or foam-formers are: for example, nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulphonates, alkyl sulphates, arylsulphonates and also protein hydrolysates; suitable dispersants are nonionic and/or ionic substances, for example from the classes of the alcohol-POE and/or -POP ethers, acid and/or POP POE esters, alkylaryl and/or POP POE ethers, fat and/or POP POE adducts, POE- and/or POP-polyol derivatives, POE- and/or POP-sorbitan or -sugar adducts, alkyl or aryl sulphates, alkyl- or arylsulphonates and alkyl or aryl phosphates or the corresponding PO-ether adducts. Furthermore, suitable oligo- or polymers, for example those derived from vinylic monomers, from acrylic acid, from EO and/or PO alone or in combination with, for example, (poly)alcohols or (poly)amines. It is also possible to employ lignin and its sulphonic acid derivatives, unmodified and modified celluloses, aromatic and/or aliphatic sulphonic acids and their adducts with formaldehyde.
Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, as well as natural phospholipids such as cephalins and lecithins, and synthetic phospholipids, can be used in the formulations.
It is possible to use colorants such as inorganic pigments, for example iron oxide, titanium oxide and Prussian Blue, and organic dyestuffs, such as alizarin dyestuffs, azo dyestuffs and metal phthalocyanine dyestuffs, and trace nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.
Other possible additives are perfumes, mineral or vegetable, optionally modified oils, waxes and nutrients (including trace nutrients), such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.
Stabilizers, such as low-temperature stabilizers, preservatives, antioxidants, light stabilizers or other agents which improve chemical and/or physical stability may also be present.
These individual types of formulation are known in principle and are described, for example, in: “Pesticides Formulations”, 2nd Ed., Marcel Dekker N.Y.; Martens, 1979. “Spray Drying Handbook”, 3rd Ed., G. Goodwin Ltd. London.
Based on his general expert knowledge, the person skilled in the art is able to choose suitable formulation auxiliaries (in this context, see, for example, Watkins, “Handbook of Insecticide Dust Diluents and Carriers”, 2nd Ed., Darland Books, Caldwell N.J.).
In a preferred embodiment, the plants or plant parts are treated according to the invention with an oil-based suspension concentrate. An advantageous suspension concentrate is known from WO 2005/084435 (EP 1 725 104 A2). It consists of at least one room-temperature-solid active agrochemical substance, at least one “closed” penetrant, at least one vegetable oil or mineral oil, at least one nonionic surfactant and/or at least one anionic surfactant, and optionally one or more additives from the groups of the emulsifiers, foam inhibitors, preservatives, antioxidants, colorants and/or inert filler materials. Preferred embodiments of the suspension concentrate are described in the above-mentioned WO 2005/084435. For the purpose of the disclosure, both documents are incorporated herein in their entirety by way of reference.
In a further preferred embodiment, the plants or plant parts are treated according to the invention with compositions comprising ammonium or phosphonium salts and, if appropriate, penetrants. Advantageous compositions are known from WO2007/068355 and from the not prior-published EP 07109732.3. They consist of at least one compound of the formula (I) and at least one ammonium or phosphonium salt and, if appropriate, penetrants. Preferred embodiments are described in WO2007/068355 and the not prior-published EP 07109732.3. For the purpose of the disclosure, these documents are incorporated herein in their entirety by way of reference.
In general, the formulations comprise from 0.01 to 98% by weight of active compound, preferably from 0.5 to 90%. In wettable powders, the active compound concentration is, for example, from about 10 to 90% by weight, the remainder to 100% by weight consisting of customary formulation components. In the case of emulsifiable concentrates, the active compound concentration can be from about 5 to 80% by weight. In most cases, formulations in the form of dusts comprise from 5 to 20% by weight of active compound, sprayable solutions comprise about 2 to 20% by weight. In the case of granules, the active compound content depends partially on whether the active compound is present in liquid or solid form and on which granulation auxiliaries, fillers, etc. are used.
The required application rate may also vary with external conditions such as, inter alia, temperature and humidity. It may vary within wide limits, for example between 0.1 g/h and 5.0 kg/ha or more of active substance. However, they are preferably between 0.1 g/ha and 1.0 kg/ha. Owing to the synergistic effects between Bt vegetables and the insecticide, particular preference is Oven to application rates of from 0.1 to 500 g/ha.
For compounds of the formula (I), preference is given to application rates of from 10 to 500 g/ha; particularly preferred are from 10 to 200 g/ha.
In a particular embodiment of the method according to the invention, the compound of the formula (I) is employed in an application rate of from 0.1 g/ha to 5.0 kg/ha, preferably from 0.1 to 500 g/ha and particularly preferably from 50 to 500 g/ha and especially preferably from 50 to 200 g/ha.
In their commercial formulations and in the use forms prepared from these formulations, the active compounds according to the invention may be present as mixtures with other active compounds, such as insecticides, attractants, sterilants, acaricides, nematicides, fungicides, growth-regulating substances or herbicides.
Particularly favourable mixing components are, for example, the following compounds:
Fungicides:
inhibitors of nucleic acid synthesis
benalaxyl, benalaxyl-M, bupirimate, chiralaxyl, clozylacon, dimethirimol, ethirimol, furalaxyl, hymexazole, metalaxyl, metalaxyl-M, ofurace, oxadixyl, oxolinic acid
inhibitors of mitosis and cell division
benomyl, carbendazim, diethofencarb, fuberidazole, pencycuron, thiabendazole, thiophanate-methyl, zoxamide
inhibitors of respiratory chain complex I/II
diflumetorim
bixafen, boscalid, carboxin, fenfuram, fluopyram, flutolanil, furametpyr, mepronil oxycarboxin, penthiopyrad, thifluzamide, N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide
inhibitors of respiratory chain complex III
amisulbrom azoxystrobin, cyazofamid, dimoxystrobin, enestrobin, famoxadone, fenamidone, fluoxastrobin, kresoxim-methyl metominostrobin, orysastrobin, pyraclostrobin, pyribencarb, picoxystrobin, trifloxystrobin
decouplers
dinocap, fluazinam
inhibitors of ATP production
fentin acetate, fentin chloride, fentin hydroxide, silthiofam
inhibitors of amino acid biosynthesis and protein biosynthesis
andoprim, blasticidin-S, cyprodinil, kasugamycin, kasugamycin hydrochloride hydrate, mepanipyrim, pyrimethanil
inhibitors of signal transduction
fenpiclonil, fludioxonil, quinoxyfen
inhibitors of lipid and membrane synthesis
chlozolinate, iprodione, procymidone, vinclozolin
ampropylfos, potassium-ampropylfos, edifenphos, iprobenfos (IBP), isoprothiolane, pyrazophos
tolclofos-methyl, biphenyl
iodocarb, propamocarb, propamocarb hydrochloride
inhibitors of ergosterol biosynthesis
fenhexamid,
azaconazole, bitertanol, bromuconazole, cyproconazole, diclobutrazole, difenoconazole, diniconazole, diniconazole-M, epoxiconazole, etaconazole, fenbuconazole, fluquinconazole, fusilazole, flutriafol, furconazole, furconazole-cis, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, paclobutrazole, penconazole, propiconazole, prothioconazole, simeconazole, spiroxamine, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, uniconazole, voriconazole, imazalil, imazalil sulphate, oxpoconazole, fenarimol, flurprimidole, nuarimol, pyrifenox, triforine, pefurazoate, prochloraz, triflumizole, viniconazole,

aldimorph, dodemorph, dodemorph acetate, fenpropimorph, tridemorph, fenpropidin, spiroxamine,

naftifine, pyributicarb, terbinafine

inhibitors of cell wall synthesis

benthiavalicarb, bialaphos, dimethomorph, flumorph, iprovalicarb, polyoxins, polyoxorim, validamycin A

inhibitors of melanin biosynthesis

capropamid, diclocymet, fenoxanil, phthalid, pyroquilon, tricyclazole

resistance inductors

acibenzolar-S-methyl, probenazole, tiadinil

multisite

captafol, captan, chlorothalonil, copper salts such as: copper hydroxide, copper naphthenate, copper oxychloride, copper sulphate, copper oxide, oxine-copper and Bordeaux mixture, dichlofluanid, dithianon, dodine, dodine free base, ferbam, folpet, fluorofolpet, guazatine, guazatine acetate, iminoctadine, iminoctadine albesilate, iminoctadine triacetate, mancopper, mancozeb, maneb, metiram, metiram zinc, propineb, sulphur and sulphur preparations containing calcium polysulphide, thiram, tolylfluanid, zineb, ziram

unknown mechanism

amibromdol, benthiazole, bethoxazin, capsimycin, carvone, chinomethionat, chloropicrin, cufraneb, cyflufenamid, cymoxanil, dazomet, debacarb, diclomezine, dichlorophen, dicloran, difenzoquat, difenzoquat methyl sulphate, diphenylamine, ethaboxam, ferimzone, flumetover, flusulfamide, fluopicolid, fluoroimid, fosetyl-A1, hexachlorobenzene, 8-hydroxyquinoline sulphate, iprodione, irumamycin, isotianil, methasulfocarb, metrafenone, methyl isothiocyanate, mildiomycin, natamycin, nickel dimethyl dithiocarbamate, nitrothal-isopropyl octhilinone, oxamocarb, oxyfenthiin, pentachlorophenol and salts, 2-phenylphenol and salts, piperalin, propanosine-sodium, proquinazid, pyrrolnitrin, quintozene, tecloftalam, tecnazene, triazoxide, trichlamide, zarilamid and 2,3,5,6-tetrachloro-4-(methylsulphonyl)pyridine, N-(4-chloro-2-nitrophenyl)-N-ethyl-4-methylbenzenesulphonamide, 2-amino-4-methyl-N-phenyl-5-thiazolecarboxamide, 2-chloro-N-(2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl)-3-pyridinecarboxamide, 3-[5-(4-chlorophenyl)-2,3-dimethylisoxazolidin-3-yl]pyridine, cis-1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)cycloheptanol, 2,4-dihydro-5-methoxy-2-methyl-4-[[[[1-[3(trifluoromethyl)phenyl]ethylidene]amino]-oxy]methyl]phenyl]-3H-1,2,3-triazol-3-one (185336-79-2), methyl 1-(2,3-dihydro-2,2-dimethyl-1H-inden-1-yl)-1H-imidazole-5-carboxylate, 3,4,5-trichloro-2,6-pyridinedicarbonitrile, methyl [[[cyclopropyl[(4-methoxyphenyl)imino]methyl]thio]methyl]-.alpha.-(methoxymethylene)benzacetate, 4-chloro-alpha-propynyloxy-N-[2-[3-methoxy-4-(2-propynyloxy]phenyl]ethyl]benzacetamide, (2S)—N-[2-[4-[[3-(4-chlorophenyl)-2-propynyl]oxy]-3-methoxyphenyl]ethyl]-3-methyl-2-[(methylsulphonyl)amino]butanamide, 5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine, 5-chloro-6-(2,4,6-trifluorophenyl)-N-[(1R)-1,2,2-trimethylpropyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine, 5-chloro-N-[(1R)-1,2-dimethylpropyl]-6-(2,4,6-trifluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, N-[1-(5-bromo-3-chloropyridin-2-yl)ethyl]-2,4-dichloronicotinamide, N-(5-bromo-3-chloropyridin-2-yl)methyl-2,4-dichloronicotinamide, 2-butoxy-6-iodo-3-propylbenzopyranon-4-one, N-{(Z)-[(cyclopropylmethoxy)imino][6-(difluoromethoxy)-2,3-difluorophenyl]methyl}-2-benzacetamide, N-(3-ethyl-3,5,5-trimethylcyclohexyl)-3-formylamino-2-hydroxybenzamide, 2-[[[[1-[3(1-fluoro-2-phenylethyl)oxy]phenyl]ethylidene]amino]oxy]methyl]-alpha-(methoxyimino)-N-methyl-alphaE-benzacetamide, N-(2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl)-2-(trifluoromethyl)benzamide, N-(3′,4′-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide, N-(6-methoxy-3-pyridinyl)cyclopropanecarboxamide, 1-[(4-methoxyphenoxy)methyl]-2,2-dimethylpropyl-1H-imidazole-1-carboxylic acid, O-[1-[(4-methoxyphenoxy)methyl]-2,2-dimethylpropyl]-1H-imidazole-1-carbothioic acid, 2-(2-{[6-(3-chloro-2-methylphenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)-2-(methoxyimino)-N-methylacetamide

Bactericides:

bronopol, dichlorophen, nitrapyrin, nickel dimethyldithiocarbamate, kasugamycin, octhilinone, furancarboxylic acid, oxytetracycline, probenazole, streptomycin, tecloftalam, copper sulphate and other copper preparations.

Insecticides/Acaricides/Nematicides:

acetylcholine esterase (AChE) inhibitors

carbamates,

for example alanycarb, aldicarb, aldoxycarb, allyxycarb, aminocarb, bendiocarb, benfuracarb, bufencarb, butacarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, cloethocarb, dimetilan, ethiofencarb, fenobucarb, fenothiocarb, fenoxycarb, formetanate, furathiocarb, isoprocarb, metam-sodium, methiocarb, methomyl, metolcarb, oxamyl, pirimicarb, promecarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb, triazamate

organophosphates,

for example acephate, azamethiphos, azinphos (-methyl, -ethyl), bromophos-ethyl, bromfenvinfos (-methyl), butathiofos, cadusafos, carbophenothion, chlorethoxyfos, chlorfenvinphos, chlormephos, chlorpyrifos (-methyl/-ethyl), coumaphos, cyanofenphos, cyanophos, chlorfenvinphos, demeton-S-methyl, demeton-S-methylsulphone, dialifos, diazinon, dichlofenthion, dichlorvos/DDVP, dicrotophos, dimethoate, dimethylvinphos, dioxabenzofos, disulfoton, EPN, ethion, ethoprophos, etrimfos, famphur, fenamiphos, fenitrothion, fensulfothion, fenthion, flupyrazofos, fonofos, formothion, fosmethilan, fosthiazate, heptenophos, iodofenphos, iprobenfos, isazofos, isofenphos, isopropyl O-salicylate, isoxathion, malathion, mecarbam, methacrifos, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion (-methyl/-ethyl), phenthoate, phorate, phosalone, phosmet, phosphamidon, phosphocarb, phoxim, pirimiphos (-methyl/-ethyl), profenofos, propaphos, propetamphos, prothiofos, prothoate, pyraclofos, pyridaphenthion, pyridathion, quinalphos, sebufos, sulfotep, sulprofos, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, triclorfon, vamidothion

sodium channel modulators/voltage-dependent sodium channel blockers

pyrethroids,

for example acrinathrin, allethrin (d-cis-trans, d-trans), beta-cyfluthrin, bifenthrin, bioallethrin, bioallethrin-S-cyclopentyl isomer, bioethanomethrin, biopermethrin, bioresmethrin, chlovaporthrin, cis-cypermethrin, cis-resmethrin, cis-permethrin, clocythrin, cycloprothrin, cyfluthrin, cyhalothrin, cypermethrin (alpha-, beta-, theta-, zeta-), cyphenothrin, deltamethrin, efusilanate, empenthrin (1R isomer), esfenvalerate, etofenprox, fenfluthrin, fenpropathrin, fenpyrithrin, fenvalerate, flubrocythrinate, flucythrinate, flufenprox, flumethrin, fluvalinate, fubfenprox, gamma-cyhalothrin, imiprothrin, kadethrin, lambda-cyhalothrin, metofluthrin, permethrin (cis-, trans-), phenothrin (1R-trans isomer), prallethrin, profluthrin, protrifenbute, pyresmethrin, pyrethrin, resmethrin, RU 15525, silafluofen, tau-fluvalinate, tefluthrin, terallethrin, tetramethrin (1R isomer), tralomethrin, transfluthrin, ZXI 8901, pyrethrins (pyrethrum)

DDT

oxadiazine,

for example indoxacarb

semicarbazones,

for example metaflumizone (BAS3201)

acetylcholine receptor agonists/antagonists

chloronicotinyls,

for example acetamiprid, AKD 1022, clothianidin, dinotefuran, imidacloprid, imidaclothiz, niten-pyram, nithiazine, thiacloprid, thiamethoxam

nicotine, bensultap, cartap

acetylcholine receptor modulators

spinosyns,

for example spinosad, spinetoram

GABA-controlled chloride channel antagonists

organochlorines,

for example camphechlor, chlordane, endosulfan, gamma-HCH, HCH, heptachlor, lindane, methoxychlor

fiproles,

for example acetoprole, ethiprole, fipronil, pyrafluprole, pyriprole, vaniliprole

chloride channel activators

mectine,

for example abamectin, emamectin, emamectin-benzoate, ivermectin, lepimectin, milbemycin

    
    
        juvenile hormone mimetics,

for example diofenolan, epofenonane, fenoxycarb, hydroprene, kinoprene, methoprene, pyri-proxifen, triprene

ecdysone agonists/disruptors

diacylhydrazines,

for example chromafenozide, halofenozide, methoxyfenozide, tebufenozide

chitin biosynthesis inhibitors

benzoylureas,

for example bistrifluron, chlofluazuron, diflubenzuron, fluazuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, penfluoron, teflubenzuron, triflumuron

        buprofezin
        cyromazine

Oxidative phosphorylation inhibitors, ATP disruptors

        diafenthiuron
        organotin compounds,

for example azocyclotin, cyhexatin, fenbutatin oxide

oxidative phosphorylation decouplers acting by interrupting the H-proton gradient

pyrroles,

for example chlorfenapyr

dinitrophenols,

for example binapacyrl, dinobuton, dinocap, DNOC, meptyldinocap

Site-I electron transport inhibitors

METI's,

for example fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad, tolfenpyrad

hydramethylnon

dicofol

Site-II electron transport inhibitors

rotenone

Site-III electron transport inhibitors

acequinocyl, fluacrypyrim

microbial disruptors of the insect gut membrane

Bacillus thuringiensis strains

Lipid synthesis inhibitors

tetronic acids,

for example spirodiclofen, spiromesifen

tetramic acids,

for example spirotetramate, cis-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one

carboxamides,

for example flonicamid

octopaminergic agonists,

for example amitraz

inhibitors of magnesium-stimulated ATPase,

        propargite
        nereistoxin analogues,
        for example thiocyclam hydrogen oxalate, thiosultap-sodium

Ryanodine receptor agonists,

benzodicarboxamides,

for example flubendiamides

anthranilamides,

for example Rynaxypyr (3-bromo-N-{4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide), Cyazapyr (ISO-proposed) (3-bromo-N-{4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide) (known from WO 2004067528)

biologicals, hormones or pheromones

azadirachtin, Bacillus spec. Beauveria spec. codlemone, Metarrhizium spec., Paecilomyces spec., thuringiensin, Verticillium spec.

active compounds with unknown or unspecific mechanisms of action

fumigants,

for example aluminium phosphide, methyl bromide, sulphuryl fluoride

antifeedants,

for example cryolite, flonicamid, pymetrozine

mite growth inhibitors,

for example clofentezine, etoxazole, hexythiazox

amidoflumet, benclothiaz, benzoximate, bifenazate, bromopropylate, buprofezin, chinomethionat, chlordimeform, chlorobenzilate, chloropicrin, clothiazobe, cycloprene, cyflumetofen, dicyclanil, fenoxacrim, fentrifanil, flubenzimine, flufenerim, flutenzin, gossyplure, hydramethylnone, japonilure, metoxadiazone, petroleum, piperonyl butoxide, potassium oleate, pyridalyl, sulfluramid, tetradifon, tetrasul, triarathene, verbutin or cyflumetofen, cyanopyrafen.

    
    


A mixture with other known compounds, such as herbicides, fertilizers, growth regulators, safeners, semiochemicals, or else with agents for improving plant properties is also possible.
The active compound content of the use forms prepared from the commercial formulations can be from 0.00000001 to 95% by weight, preferably between 0.00001 and 1% by weight, of active compound.







TABLE 1







Plant: Maize








Structure affected or principle expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acid,



cyclohexanedione


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylates, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1
xenobiotics and herbicides, such as



sulphonylurea


dimboa biosynthesis (Bx1-Gen)
Helminthosporium turcicum,



Rhopalosiphum maydis, Diplodia



maydis, Ostrinia nubilalis, Lepidoptera sp.


CMIII (small basic peptide building block
plant pathogens e.g. Fusarium, Alternaria,


from maize grain)
Sclerotina


Com-SAFP (zeamatin)
plant pathogens, e.g. Fusarium,



Alternaria, Sclerotina, Rhizoctonia,



Chaetomium, Phycomycen


Hm1-gene
Cochliobulus


chitinases
plant pathogens


glucanases
plant pathogens


envelope proteins
viruses, such as the Maize dwarf mosaic virus



(MDMV)


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, Coleoptera, Diptera,


Bacillus cereus toxin, Photorabdus and
nematodes, e.g. Ostrinia nubilalis,


Xenorhabdus toxins
Heliothis zea, armyworms e.g.



Spodoptera frugiperda, Western corn



rootworm, Sesamia sp., Aprotis ipsilon, Asian



corn borer, weevils


3-hydroxysteroid oxidase
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon,



Asian corn borer, weevils


peroxidase
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon, Asian corn borer, weevils


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, Coleoptera, Diptera,


aminopeptidase inhibitors (LAPI)
nematodes, e.g. Ostrinia nubilalis,



Heliothis zea, armyworms e.g. Spodoptera



frugiperda, Western corn rootworm, Sesamia



sp., Aprotis ipsilon, Asian corn borer, weevils


limonene synthase
Western corn rootworm


lectin
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon, Asian corn borer, weevils


protease inhibitors e.g. cystatin, patatin,
weevils, Western corn rootworm


virgiferin, CPTI


ribosome-inactivating protein
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon, Asian corn borer, weevils


5C9-maize polypeptide
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon, Asian corn borer, weevils


HMG-CoA reductase
Lepidoptera, Coleoptera, Diptera, nematodes,



e.g. Ostrinia nubilalis, Heliothis zea,



armyworms e.g. Spodoptera frugiperda,



Western corn rootworm, Sesamia sp., Aprotis



ipsilon, Asian corn borer, weevils










Plant: Wheat








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acid,



cyclohexanedione


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol



or isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1
xenobiotics and herbicides, such as



sulphonylurea compounds


antifungal polypeptide AlyAFP
plant pathogens, e.g. Septoria and Fusarium


glucose oxidase
plant pathogens, e.g. Fusarium, Septoria


pyrrolnitrin synthesis gene
plant pathogens, e.g. Fusarium, Septoria


serine/threonine kinases
plant pathogens, e.g. Fusarium, Septoria



and other diseases


polypeptide having the effect of triggering
plant pathogens, e.g. Fusarium, Septoria and


a hypersensitivity reaction
other diseases


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
plant pathogens


glucanases
plant pathogens


double-strand ribonuclease
viruses such as, for example, BYDV and



MSMV


envelope proteins
viruses such as, for example, BYDV and



MSMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, Coleoptera, Diptera,


Bacillus cereus toxins, Photorabdus and
nematodes


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, Coleoptera, Diptera,



nematodes


peroxidase
Lepidoptera, Coleoptera, Diptera,



nematodes


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, Coleoptera, Diptera,


aminopeptidase inhibitor
nematodes


lectins
Lepidoptera, Coleoptera, Diptera,



nematodes, aphids


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, Coleoptera, Diptera,


virgiferin, CPTI
nematodes, aphids


ribosome-inactivating protein
Lepidoptera, Coleoptera, Diptera,



nematodes, aphids


HMG-CoA reductase
Lepidoptera, Coleoptera, Diptera,



nematodes, e.g. Ostrinia nubilalis,



Heliothis zea, armyworms e.g. Spodoptera



frugiperda, Western corn rootworm, Sesamia



sp., Aprotis ipsilon, Asian corn borer, weevils










Plant: Barley








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1
xenobiotics and herbicides, such as



sulphonylurea compounds


antifungal polypeptide AlyAFP
plant pathogens, e.g. Septoria and Fusarium


glucose oxidase
plant pathogens, e.g. Fusarium, Septoria


pyrrolnitrin synthesis gene
plant pathogens, e.g. Fusarium, Septoria


serine/threonine kinases
plant pathogens, e.g. Fusarium, Septoria



and other diseases


polypeptide having the effect of triggering
plant pathogens, e.g. Fusarium, Septoria and


a hypersensitivity reaction
other diseases


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
plant pathogens


glucanases
plant pathogens


double-strand ribonuclease
viruses such as, for example, BYDV and



MSMV


envelope proteins
viruses such as, for example, BYDV and



MSMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, Coleoptera, Diptera,


Bacillus cereus toxins, Photorabdus and
nematodes


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, Coleoptera, Diptera,



nematodes


peroxidase
Lepidoptera, Coleoptera, Diptera,



nematodes


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, Coleoptera, Diptera,


aminopeptidase inhibitor
nematodes


lectins
Lepidoptera, Coleoptera, Diptera,



nematodes, aphids


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, Coleoptera, Diptera,


virgiferin, CPTI
nematodes, aphids


ribosome-inactivating protein
Lepidoptera, Coleoptera, Diptera,



nematodes, aphids


HMG-CoA reductase
Lepidoptera, Coleoptera, Diptera,



nematodes, aphids










Plant: Rice








Structure affected/principle expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acid,



cyclohexanedione


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1
xenobiotics and herbicides, such as



sulphonylurea compounds


antifungal polypeptide AlyAFP
plant pathogens


glucose oxidase
plant pathogens


pyrrolnitrin synthesis gene
plant pathogens


serine/threonine kinases
plant pathogens


phenylalanine ammonia lyase (PAL)
plant pathogens, e.g. bacterial



foliar mildew and inducible rice blast


phytoalexins
plant pathogens, e.g. bacterial



foliar mildew and rice blast


B-1,3-glucanase (antisense)
plant pathogens, e.g. bacterial



foliar mildew and rice blast


receptor kinase
plant pathogens, e.g. bacterial



foliar mildew and rice blast


polypeptide having the effect of triggering
plant pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
plant pathogens, e.g. bacterial



foliar mildew and rice blast


glucanases
plant pathogens


double-strand ribonuclease
viruses such as, for example, BYDV and



MSMV


envelope proteins
viruses such as, for example, BYDV and



MSMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, e.g. stem borer, Coleoptera,


Bacillus cereus toxins, Photorabdus and
e.g. weevils such as Lissorhoptrus oryzophilus,


Xenorhabdus toxins
Diptera, rice planthoppers, e.g. rice brown



planthopper


3-hydroxysteroid oxidase
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus oryzophilus,



Diptera, rice planthoppers, e.g. rice brown



planthopper


peroxidase
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus oryzophilus,



Diptera, rice planthoppers, e.g. rice brown



planthopper


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, e.g. stem borer, Coleoptera,


aminopeptidase inhibitor
e.g. weevils such as Lissorhoptrus



oryzophilus, Diptera, rice planthoppers, e.g.



rice brown planthopper


lectins
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus



oryzophilus, Diptera, rice planthoppers, e.g.



rice brown planthopper


protease inhibitors
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus oryzophilus,



Diptera, rice planthoppers e.g. rice brown



planthopper


ribosome-inactivating protein
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus



oryzophilus, Diptera, rice planthoppers, e.g.



rice brown planthopper


HMG-CoA reductase
Lepidoptera, e.g. stem borer, Coleoptera,



e.g. weevils such as Lissorhoptrus



oryzophilus, Diptera, rice planthoppers e.g.



rice brown planthopper










Plant: Soya bean








Structure affected/principle expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides, such as



sulphonylurea compounds


antifungal polypeptide AlyAFP
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


oxalate oxidase
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


glucose oxidase
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


pyrrolnitrin synthesis gene
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


serine/threonine kinases
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


phytoalexins
plant pathogens, e.g. bacterial foliar



mildew and rice blast


B-1,3-glucanase (antisense)
plant pathogens, e.g. bacterial foliar



mildew and rice blast


receptor kinase
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


polypeptide having the effect of triggering
plant pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


glucanases
bacterial and fungal pathogens such as, for



example, Fusarium, Sclerotinia, stem rot


double-strand ribonuclease
viruses such as, for example, BPMV and



SbMV


envelope proteins
viruses such as, for example, BYDV and



MSMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, Coleoptera, aphids


Bacillus cereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, Coleoptera, aphids


peroxidase
Lepidoptera, Coleoptera, aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, Coleoptera, aphids


aminopeptidase inhibitor


lectins
Lepidoptera, Coleoptera, aphids


protease inhibitors, e.g. virgiferin
Lepidoptera, Coleoptera, aphids


ribosome-inactivating protein
Lepidoptera, Coleoptera, aphids


HMG-CoA reductase
Lepidoptera, Coleoptera, aphids


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


hatching factor for cyst nematodes
cyst nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and



cyst nematodes










Plant: Potato








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides, such as



sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
black spot


(antisense)


metallothionein
bacterial and fungal pathogens such as, for



example, Phytophtora,


ribonuclease
Phytophtora, Verticillium, Rhizoctonia


antifungal polypeptide AlyAFP
bacterial and fungal pathogens such as, for



example, Phytophtora


oxalate oxidase
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


glucose oxidase
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


pyrrolnitrin synthesis gene
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


serine/threonine kinases
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


cecropin B
bacteria such as, for example, Coryne-



bacterium sepedonicum, Erwinia carotovora


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


phytoalexins
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


B-1,3-glucanase (antisense)
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


receptor kinase
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


polypeptide having the effect of triggering
bacterial and fungal pathogens such as, for


a hypersensitivity reaction
example, Phytophtora, Verticillium, Rhizoctonia


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


barnase
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


gene 49 for controlling disease resistance
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


trans-aldolase (antisense)
black spot


glucanases
bacterial and fungal pathogens such as, for



example, Phytophtora, Verticillium, Rhizoctonia


double-strand ribonuclease
viruses such as, for example, PLRV, PVY and



TRV


envelope proteins
viruses such as, for example, PLRV, PVY and



TRV


17 kDa or 60 kDa protein
viruses such as, for example, PLRV, PVY and



TRV


nuclear inclusion proteins, e.g. a or b
viruses such as, for example, PLRV, PVY and



TRV


pseudoubiquitin
viruses such as, for example, PLRV, PVY and



TRV


replicase
viruses such as, for example, PLRV, PVY and



TRV


toxins of Bacillus thuringiensis, VIP 3,
Coleoptera, e.g. Colorado beetle, aphids


Bacillus cereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Coleoptera, e.g. Colorado beetle, aphids


peroxidase
Coleoptera, e.g. Colorado beetle, aphids


aminopeptidase inhibitors, e.g. leucine
Coleoptera, e.g. Colorado beetle, aphids


aminopeptidase inhibitor


stilbene synthase
Coleoptera, e.g. Colorado beetle, aphids


lectins
Coleoptera, e.g. Colorado beetle, aphids


protease inhibitors, e.g. cystatin, patatin
Coleoptera, e.g. Colorado beetle, aphids


ribosomene-inactivating protein
Coleoptera, e.g. Colorado beetle, aphids


HMG-CoA reductase
Coleoptera, e.g. Colorado beetle, aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and



cyst nematodes










Plant: Tomato








Structure affected/principle expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolepyrimidines, pyrimidyloxybenzoates,



phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acid,



cyclohexanedione


hydroxyphenylpyruvate dioxygenase (HPPD)
isooxazoles, such as isoxaflutol or



isoxachlortol,



triones, such as mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles, such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides, such as



sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
black spot


(antisense)


metallothionein
bacterial and fungal pathogens such as, for



example, Phytophtora


ribonuclease
Phytophtora, Verticillium, Rhizoctonia


antifungal polypeptide AlyAFP
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


oxalate oxidase
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


glucose oxidase
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


pyrrolnitrin synthesis gene
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


serine/threonine kinases
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


cecropin B
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2
leaf mould


osmotin
early blight


alpha hordothionin
bakteria


systemin
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


polygalacturonase inhibitors
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


Prf control gene
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


12 fusarium resistance site
Fusarium


phytoalexins
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


B-1,3-glucanase (antisense)
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


receptor kinase
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


polypeptide having the effect of triggering
bacterial and fungal pathogens such as, for


a hypersensitivity reaction
example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


barnase
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


glucanases
bacterial and fungal pathogens such as, for



example, bacterial blotch, Fusarium,



soft rot, powdery mildew, foliar blight,



leaf mould etc.


double-strand ribonuclease
viruses such as, for example, PLRV, PVY and



ToMoV


envelope proteins
viruses such as, for example, PLRV, PVY and



ToMoV


17 kDa or 60 kDa protein
viruses such as, for example, PLRV, PVY and



ToMoV


nuclear inclusion proteins e.g. a or b or
viruses such as, for example, PLRV, PVY and



ToMoV


nucleoprotein
TRV


pseudoubiquitin
viruses such as, for example, PLRV, PVY and



ToMoV


replicase
viruses such as, for example, PLRV, PVY and



ToMoV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera e.g. Heliothis, whitefly


Bacilluscereus toxins, Photorabdus and
aphids


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera e.g. Heliothis, whitefly,



aphids


peroxidase
Lepidoptera e.g. Heliothis, whitefly,



aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera e.g. Heliothis, whitefly,


aminopeptidase inhibitor
aphids


lectins
Lepidoptera e.g. Heliothis, whitefly,



aphids


protease inhibitors, e.g. cystatin, patatin
Lepidoptera e.g. Heliothis, whitefly,



aphids


ribosome-inactivating protein
Lepidoptera e.g. Heliothis, whitefly,



aphids


stilbene synthase
Lepidoptera e.g. Heliothis, whitefly,



aphids


HMG-CoA reductase
Lepidoptera e.g. Heliothis, whitefly,



aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and



cyst nematodes










Plant: Bell Pepper








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial and fungal pathogens


(antisense)


metallothionein
bacterial and fungal pathogens


ribonuclease
bacterial and fungal pathogens


antifungal polypeptid AlyAFP
bacterial and fungal pathogens


oxalate oxidase
bacterial and fungal pathogens


glucose oxidase
bacterial and fungal pathogens


pyrrolnitrin synthesis genes
bacterial and fungal pathogens


serine/threonine kinases
bacterial and fungal pathogens


cecropin B
bacterial and fungal pathogens, rot,



leaf mould, etc.


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens


Cf genes, e.g. Cf9 Ct5 Cf4 Cf2
bacterial and fungal pathogens


osmotin
bacterial and fungal pathogens


alpha hordothionine
bacterial and fungal pathogens


systemin
bacterial and fungal pathogens


polygalacturonase inhibitors
bacterial and fungal pathogens


Prf control gene
bacterial and fungal pathogens


12 Fusarium resistance site
Fusarium


phytoalexins
bacterial and fungal pathogens


B-1,3-glucanase (antisense)
bacterial and fungal pathogens


receptor kinase
bacterial and fungal pathogens


polypeptide having the effect of triggering
bacterial and fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens


barnase
bacterial and fungal pathogens


glucanases
bacterial and fungal pathogens


double-strand ribonuclease
viruses such as, for example, CMV, TEV


envelope proteins
viruses such as, for example, CMV, TEV


17 kDa or 60 kDa protein
viruses such as, for example, CMV, TEV


nuclear inclusion proteins e.g. a or b or
viruses such as, for example, CMV, TEV


nucleoprotein


pseudoubiquitin
viruses such as, for example, CMV, TEV


replicase
viruses such as, for example, CMV, TEV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, whitefly, aphids


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, whitefly, aphids


peroxidase
Lepidoptera, whitefly, aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, whitefly, aphids


aminopeptidase inhibitor


lectins
Lepidoptera, whitefly, aphids


protease inhibitors, e.g. cystatin, patatin
Lepidoptera, whitefly, aphids


ribosome-inactivating protein
Lepidoptera, whitefly, aphids


stilbene synthase
Lepidoptera, whitefly, aphids


HMG-CoA reductase
Lepidoptera, whitefly, aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and



cyst nematodes










Plant: Grapevines








Structure affected/principle expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial and fungal pathogens such as


(antisense)
Botrytis and powdery mildew


metallothionein
bacterial and fungal pathogens such as



Botrytis and powdery mildew


ribonuclease
bacterial and fungal pathogens such as



Botrytis and powdery mildew


antifungal polypeptide AlyAFP
bacterial and fungal pathogens such as



Botrytis and powdery mildew


oxalate oxidase
bacterial and fungal pathogens such as



Botrytis and powdery mildew


glucose oxidase
bacterial and fungal pathogens such as



Botrytis and powdery mildew


pyrrolnitrin synthesis genes
bacterial and fungal pathogens such as



Botrytis and powdery mildew


serine/threonine kinases
bacterial and fungal pathogens such as



Botrytis and powdery mildew


cecropin B
bacterial and fungal pathogens such as



Botrytis and powdery mildew


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as



Botrytis and powdery mildew


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial and fungal pathogens such as



Botrytis and powdery mildew


osmotin
bacterial and fungal pathogens such as



Botrytis and powdery mildew


alpha hordothionine
bacterial and fungal pathogens such as



Botrytis and powdery mildew


systemin
bacterial and fungal pathogens such as



Botrytis and powdery mildew


polygalacturonase inhibitors
bacterial and fungal pathogens such as



Botrytis and powdery mildew


Prf control gene
bacterial and fungal pathogens such as



Botrytis and powdery mildew


phytoalexins
bacterial and fungal pathogens such as



Botrytis and powdery mildew


B-1,3-glucanase (antisense)
bacterial and fungal pathogens such as



Botrytis and powdery mildew


receptor kinase
bacterial and fungal pathogens such as



Botrytis and powdery mildew


polypeptide having the effect of triggering
bacterial and fungal pathogens such as Botrytis


a hypersensitivity reaction
and powdery mildew


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens such as



Botrytis and powdery mildew


barnase
bacterial and fungal pathogens such as



Botrytis and powdery mildew


glucanases
bacterial and fungal pathogens such as Botrytis



and powdery mildew


double-strand ribonuclease
viruses


envelope proteins
viruses


17 kDa or 60 kDa protein
viruses


nuclear inclusion proteins e.g. a or b or
viruses


nucleoprotein


pseudoubiquitin
viruses


replicase
viruses


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids


peroxidase
Lepidoptera, aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids


aminopeptidase inhibitor


lectins
Lepidoptera, aphids


protease inhibitors, e.g. cystatin, patatin
Lepidoptera, aphids


ribosome-inactivating protein
Lepidoptera, aphids


stilbene synthase
Lepidoptera, aphids, diseases


HMG-CoA reductase
Lepidoptera, aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes or general diseases


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes



or root-cyst nematodes










Plant: Oilseed rape








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial and fungal pathogens such as


(antisense)
Cylindrosporium, Phoma, Sclerotinia


metallothionein
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


ribonuclease
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


antifungal polypeptid AlyAFP
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


oxalate oxidase
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


glucose oxidase
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


pyrrolnitrin synthesis genes
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


serine/threonine kinases
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


cecropin B
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


osmotin
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


alpha hordothionine
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


systemin
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


polygalacturonase inhibitors
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


Prf control gene
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


phytoalexins
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


B-1,3-glucanase (antisense)
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


receptor kinase
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


polypeptide having the effect of triggering
bacterial and fungal pathogens such as


a hypersensitivity reaction
Cylindrosporium, Phoma, Sclerotinia


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


barnase
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia



nematodes


glucanases
bacterial and fungal pathogens such as



Cylindrosporium, Phoma, Sclerotinia


double-strand ribonuclease
viruses


envelope proteins
viruses


17 kDa or 60 kDa protein
viruses


nuclear inclusion proteins e.g. a or b or
viruses


nucleoprotein


pseudoubiquitin
viruses


replicase
viruses


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids


peroxidase
Lepidoptera, aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids


aminopeptidase inhibitor


lectins
Lepidoptera, aphids


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids


CPTI


ribosome-inactivating protein
Lepidoptera, aphids


stilbene synthase
Lepidoptera, aphids, diseases


HMG-CoA reductase
Lepidoptera, aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Brassica vegetables (cabbage, Brussels sprouts etc.)








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial and fungal pathogens


(antisense)


metallothionein
bacterial and fungal pathogens


ribonuclease
bacterial and fungal pathogens


antifungal polypeptid AlyAFP
bacterial and fungal pathogens


oxalate oxidase
bacterial and fungal pathogens


glucose oxidase
bacterial and fungal pathogens


pyrrolnitrin synthesis genes
bacterial and fungal pathogens


serine/threonine kinases
bacterial and fungal pathogens


cecropin B
bacterial and fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens


Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2
bacterial and fungal pathogens


osmotin
bacterial and fungal pathogens


alpha hordothionine
bacterial and fungal pathogens


systemin
bacterial and fungal pathogens


polygalacturonase inhibitors
bacterial and fungal pathogens


Prf control gene
bacterial and fungal pathogens


phytoalexins
bacterial and fungal pathogens


B-1,3-glucanase (antisense)
bacterial and fungal pathogens


receptor kinase
bacterial and fungal pathogens


polypeptide having the effect of triggering
bacterial and fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


chitinases
bacterial and fungal pathogens


barnase
bacterial and fungal pathogens


glucanases
bacterial and fungal pathogens


double-strand ribonuclease
viruses


envelope proteins
viruses


17 kDa or 60 kDa protein
viruses


nuclear inclusion proteins e.g. a or b or
viruses


nucleoprotein


pseudoubiquitin
viruses


replicase
viruses


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids


peroxidase
Lepidoptera, aphids


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids


aminopeptidase inhibitor


lectins
Lepidoptera, aphids


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids


CPTI


ribosome-inactivating protein
Lepidoptera, aphids


stilbene synthase
Lepidoptera, aphids, diseases


HMG-CoA reductase
Lepidoptera, aphids


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes



cyst nematodes










Plants: Pomaceous fruit, e.g. apples, pears








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial and fungal pathogens such as


(antisense)
storage scab on apples or fire-blight


metallothionein
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


ribonuclease
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


antifungal polypeptid AlyAFP
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


oxalate oxidase
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


glucose oxidase
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


pyrrolnitrin synthesis genes
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


serine/threonine kinases
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


cecropin B
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


phenylalanine ammonia lyase (PAL)
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


osmotin
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


alpha hordothionine
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


systemin
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


polygalacturonase inhibitors
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


Prf control gene
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


phytoalexins
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


B-1,3-glucanase (antisense)
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


receptor kinase
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


polypeptide having the effect of triggering
bacterial and fungal pathogens such as


a hypersensitivity reaction
storage scab on apples or fire-blight


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


lysozyme
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


chitinases
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


barnase
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


glucanases
bacterial and fungal pathogens such as



storage scab on apples or fire-blight


double-strand ribonuclease
viruses


envelope proteins
viruses


17 kDa or 60 kDa protein
viruses


nuclear inclusion proteins e.g. a or b or
viruses


nucleoprotein


pseudoubiquitin
viruses


replicase
viruses


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites


peroxidase
Lepidoptera, aphids, mites


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites


aminopeptidase inhibitor


lectins
Lepidoptera, aphids, mites


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites


CPTI


ribosome-inactivating protein
Lepidoptera, aphids, mites


stilbene synthase
Lepidoptera, aphids, diseases, mites


HMG-CoA reductase
Lepidoptera, aphids, mites


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Melon








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens such as


(antisense)
Phytophtora


metallothionein
bacterial or fungal pathogens such as



Phytophtora


ribonuclease
bacterial or fungal pathogens such as



Phytophtora


antifungal polypeptid AlyAFP
bacterial or fungal pathogens such as



Phytophtora


oxalate oxidase
bacterial or fungal pathogens such as



Phytophtora


glucose oxidase
bacterial or fungal pathogens such as



Phytophtora


pyrrolnitrin synthesis genes
bacterial or fungal pathogens such as



Phytophtora


serine/threonine kinases
bacterial or fungal pathogens such as



Phytophtora


cecropin B
bacterial or fungal pathogens such as



Phytophtora


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens such as



Phytophtora


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial or fungal pathogens such as



Phytophtora


osmotin
bacterial or fungal pathogens such as



Phytophtora


alpha hordothionine
bacterial or fungal pathogens such as



Phytophtora


systemin
bacterial or fungal pathogens such as



Phytophtora


polygalacturonase inhibitors
bacterial or fungal pathogens such as



Phytophtora


Prf control gene
bacterial or fungal pathogens such as



Phytophtora


phytoalexins
bacterial or fungal pathogens such as



Phytophtora


B-1,3-glucanase (antisense)
bacterial or fungal pathogens such as



Phytophtora


receptor kinase
bacterial or fungal pathogens such as



Phytophtora


polypeptide having the effect of triggering
bacterial or fungal pathogens such as


a hypersensitivity reaction
Phytophtora


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens such as



Phytophtora


lysozyme
bacterial or fungal pathogens such as



Phytophtora


chitinases
bacterial or fungal pathogens such as



Phytophtora


barnase
bacterial or fungal pathogens such as



Phytophtora


glucanases
bacterial or fungal pathogens such as



Phytophtora


double-strand ribonuclease
viruses such as CMV, PRSV, WMV2, SMV,



ZYMV


envelope proteins
viruses such as CMV, PRSV, WMV2, SMV,



ZYMV


17 kDa or 60 kDa protein
viruses such as CMV, PRSV, WMV2, SMV,



ZYMV


nuclear inclusion proteins e.g. a or b or
viruses such as CMV, PRSV, WMV2, SMV,


nucleoprotein
ZYMV


pseudoubiquitin
viruses such as CMV, PRSV, WMV2, SMV,



ZYMV


replicase
viruses such as CMV, PRSV, WMV2, SMV,



ZYMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, whitefly


peroxidase
Lepidoptera, aphids, mites, whitefly


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, whitefly


aminopeptidase inhibitor


lectins
Lepidoptera, aphids, mites, whitefly


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, whitefly


CPTI, virgiferin


ribosome-inactivating protein
Lepidoptera, aphids, mites, whitefly


stilbene synthase
Lepidoptera, aphids, mites, whitefly


HMG-CoA reductase
Lepidoptera, aphids, mites, whitefly


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Banana








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens


(antisense)


metallothionein
bacterial or fungal pathogens


ribonuclease
bacterial or fungal pathogens


antifungal polypeptid AlyAFP
bacterial or fungal pathogens


oxalate oxidase
bacterial or fungal pathogens


glucose oxidase
bacterial or fungal pathogens


pyrrolnitrin synthesis genes
bacterial or fungal pathogens


serine/threonine kinases
bacterial or fungal pathogens


cecropin B
bacterial or fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial or fungal pathogens


osmotin
bacterial or fungal pathogens


alpha hordothionine
bacterial or fungal pathogens


systemin
bacterial or fungal pathogens


polygalacturonase inhibitors
bacterial or fungal pathogens


Prf control gene
bacterial or fungal pathogens


phytoalexins
bacterial or fungal pathogens


B-1,3-glucanase (antisense)
bacterial or fungal pathogens


receptor kinase
bacterial or fungal pathogens


polypeptide having the effect of triggering
bacterial or fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens


lysozyme
bacterial or fungal pathogens


chitinases
bacterial or fungal pathogens


barnase
bacterial or fungal pathogens


glucanases
bacterial or fungal pathogens


double-strand ribonuclease
viruses such as the Banana Bunchy Top Virus



(BBTV)


envelope proteins
viruses such as the Banana Bunchy Top Virus



(BBTV)


17 kDa or 60 kDa protein
viruses such as the Banana Bunchy Top Virus



(BBTV)


nuclear inclusion proteins e.g. a or b or
viruses such as the Banana Bunchy Top Virus


nucleoprotein
(BBTV)


pseudoubiquitin
viruses such as the Banana Bunchy Top Virus



(BBTV)


replicase
viruses such as the Banana Bunchy Top Virus



(BBTV)


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites, nematodes


Bacilluscereus toxins, Photorabdus and


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, nematodes


peroxidase
Lepidoptera, aphids, mites, nematodes


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, nematodes


aminopeptidase inhibitor


lectins
Lepidoptera, aphids, mites, nematodes


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, nematodes


CPTI, virgiferin


ribosome-inactivating protein
Lepidoptera, aphids, mites, nematodes


stilbene synthase
Lepidoptera, aphids, mites, nematodes


HMG-CoA reductase
Lepidoptera, aphids, mites, nematodes


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Cotton








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthese


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens


(antisense)


metallothionein
bacterial or fungal pathogens


ribonuclease
bacterial or fungal pathogens


antifungal polypeptid AlyAFP
bacterial or fungal pathogens


oxalate oxidase
bacterial or fungal pathogens


glucose oxidase
bacterial or fungal pathogens


pyrrolnitrin synthesis genes
bacterial or fungal pathogens


serine/threonine kinases
bacterial or fungal pathogens


cecropin B
bacterial or fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial or fungal pathogens


osmotin
bacterial or fungal pathogens


alpha hordothionine
bacterial or fungal pathogens


systemin
bacterial or fungal pathogens


polygalacturonase inhibitors
bacterial or fungal pathogens


Prf control gene
bacterial or fungal pathogens


phytoalexins
bacterial or fungal pathogens


B-1,3-glucanase (antisense)
bacterial or fungal pathogens


receptor kinase
bacterial or fungal pathogens


polypeptide having the effect of triggering
bacterial or fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens


lysozyme
bacterial or fungal pathogens


chitinases
bacterial or fungal pathogens


barnase
bacterial or fungal pathogens


glucanases
bacterial or fungal pathogens


double-strand ribonuclease
viruses such as the wound tumour virus (WTV)


envelope proteins
viruses such as the wound tumour virus (WTV)


17 kDa or 60 kDa protein
viruses such as the wound tumour virus (WTV)


nuclear inclusion proteins e.g. a or b or
viruses such as the wound tumour virus (WTV)


nucleoprotein


pseudoubiquitin
viruses such as the wound tumour virus (WTV)


replicase
viruses such as the wound tumour virus (WTV)


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites, nematodes,


Bacilluscereus toxins, Photorabdus and
whitefly


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, nematodes,



whitefly


peroxidase
Lepidoptera, aphids, mites, nematodes,



whitefly


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, nematodes,


aminopeptidase inhibitor
whitefly


lectins
Lepidoptera, aphids, mites, nematodes,



whitefly


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, nematodes,


CPTI, virgiferin
whitefly


ribosome-inactivating protein
Lepidoptera, aphids, mites, nematodes,



whitefly


stilbene synthase
Lepidoptera, aphids, mites, nematodes,



whitefly


HMG-CoA reductase
Lepidoptera, aphids, mites, nematodes,



whitefly


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Sugar cane








Feature affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens


(antisense)


metallothionein
bacterial or fungal pathogens


ribonuclease
bacterial or fungal pathogens


antifungal polypeptid AlyAFP
bacterial or fungal pathogens


oxalate oxidase
bacterial or fungal pathogens


glucose oxidase
bacterial or fungal pathogens


pyrrolnitrin synthesis genes
bacterial or fungal pathogens


serine/threonine kinases
bacterial or fungal pathogens


cecropin B
bacterial or fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial or fungal pathogens


osmotin
bacterial or fungal pathogens


alpha hordothionine
bacterial or fungal pathogens


systemin
bacterial or fungal pathogens


polygalacturonase inhibitors
bacterial or fungal pathogens


Prf control gene
bacterial or fungal pathogens


phytoalexins
bacterial or fungal pathogens


B-1,3-glucanase (antisense)
bacterial or fungal pathogens


receptor kinase
bacterial or fungal pathogens


polypeptide having the effect of triggering
bacterial or fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens


lysozyme
bacterial or fungal pathogens, e.g.



Clavibacter


chitinases
bacterial or fungal pathogens


barnase
bacterial or fungal pathogens


glucanases
bacterial or fungal pathogens


double-strand ribonuclease
viruses such as SCMV, SrMV


envelope proteins
viruses such as SCMV, SrMV


17 kDa or 60 kDa protein
viruses such as SCMV, SrMV


nuclear inclusion proteins e.g. a or b or
viruses such as SCMV, SrMV


nucleoprotein


pseudoubiquitin
viruses such as SCMV, SrMV


replicase
viruses such as SCMV, SrMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites, nematodes,


Bacilluscereus toxins, Photorabdus and
whitefly, beetles such as e.g. the Mexican


Xenorhabdus toxins
rice borer


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


peroxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, nematodes,


aminopeptidase inhibitor
whitefly, beetles such as e.g. the Mexican



rice borer


lectins
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, nematodes,


CPTI, virgiferin
whitefly, beetles such as e.g. the Mexican



rice borer


ribosome-inactivating protein
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


stilbene synthase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


HMG-CoA reductase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles such as e.g. the Mexican



rice borer


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plant: Sunflower








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example,



sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens


(antisense)


metallothionein
bacterial or fungal pathogens


ribonuclease
bacterial or fungal pathogens


antifungal polypeptid AlyAFP
bacterial or fungal pathogens


oxalate oxidase
bacterial or fungal pathogens, e.g.



Sclerotinia


glucose oxidase
bacterial or fungal pathogens


pyrrolnitrin synthesis genes
bacterial or fungal pathogens


serine/threonine kinases
bacterial or fungal pathogens


cecropin B
bacterial or fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens


Cf genes, e.g. Cf9 Cf5 Cf4 Cf2
bacterial or fungal pathogens


osmotin
bacterial or fungal pathogens


alpha hordothionine
bacterial or fungal pathogens


systemin
bacterial or fungal pathogens


polygalacturonase inhibitors
bacterial or fungal pathogens


Prf control gene
bacterial or fungal pathogens


phytoalexins
bacterial or fungal pathogens


B-1,3-glucanase (antisense)
bacterial or fungal pathogens


receptor kinase
bacterial or fungal pathogens


polypeptide having the effect of triggering
bacterial or fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens


lysozyme
bacterial or fungal pathogens


chitinases
bacterial or fungal pathogens


barnase
bacterial or fungal pathogens


glucanases
bacterial or fungal pathogens


double-strand ribonuclease
viruses such as CMV, TMV


envelope proteins
viruses such as CMV, TMV


17 kDa or 60 kDa protein
viruses such as CMV, TMV


nuclear inclusion proteins e.g. a or b or
viruses such as CMV, TMV


nucleoprotein


pseudoubiquitin
viruses such as CMV, TMV


replicase
viruses such as CMV, TMV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites, nematodes,


Bacilluscereus toxins, Photorabdus and
whitefly, beetles


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


peroxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, nematodes,


aminopeptidase inhibitor
whitefly, beetles


lectins
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, nematodes,


CPTI, virgiferin
whitefly, beetles


ribosome-inactivating protein
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


stilbene synthase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


HMG-CoA reductase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced at nematode feeding sites
root-cyst nematodes










Plants: Sugar beet, turnips








Structure affected/protein expressed
Feature of the plant/tolerance to





acetolactate synthase (ALS)
sulphonylurea compounds, imidazolinones



triazolopyrimidines,



pyrimidyloxybenzoates, phthalides


acetyl-CoA carboxylase (ACCase)
aryloxyphenoxyalkanecarboxylic acids,



cyclohexanediones


hydroxyphenylpyruvate dioxygenase (HPPD)
isoxazoles such as, for example, isoxaflutole or



isoxachlortole, triones such as, for example,



mesotrione or sulcotrione


phosphinothricin acetyltransferase
phosphinothricin


O-methyl transferase
modified lignin content


glutamine synthetase
glufosinate, bialaphos


adenylosuccinate lyase (ADSL)
inhibitors of IMP and AMP synthesis


adenylosuccinate synthase
inhibitors of adenylosuccinate synthesis


anthranilate synthase
inhibitors of tryptophan synthesis and



degradation


nitrilase
3,5-dihalo-4-hydroxybenzonitriles such as



bromoxynil and loxinyl


5-enolpyruvyl-3-phosphoshikimate
glyphosate or sulphosate


synthase (EPSPS)


glyphosate oxidoreductase
glyphosate or sulphosate


protoporphyrinogen oxidase (PROTOX)
diphenyl ethers, cyclic imides,



phenylpyrazoles, pyridine derivatives,



phenopylate, oxadiazoles etc.


cytochrome P450 e.g. P450 SU1 or selection
xenobiotics and herbicides such as, for



example, sulphonylurea compounds


polyphenol oxidase or polyphenol oxidase
bacterial or fungal pathogens


(antisense)


metallothionein
bacterial or fungal pathogens


ribonuclease
bacterial or fungal pathogens


antifungal polypeptid AlyAFP
bacterial or fungal pathogens


oxalate oxidase
bacterial or fungal pathogens, e.g.



Sclerotinia


glucose oxidase
bacterial or fungal pathogens


pyrrolnitrin synthesis genes
bacterial or fungal pathogens


serine/threonine kinases
bacterial or fungal pathogens


cecropin B
bacterial or fungal pathogens


phenylalanine ammonia lyase (PAL)
bacterial or fungal pathogens


Cf genes, e.g. Cf 9 Cf5 Cf4 Cf2
bacterial or fungal pathogens


osmotin
bacterial or fungal pathogens


alpha hordothionine
bacterial or fungal pathogens


systemin
bacterial or fungal pathogens


polygalacturonase inhibitors
bacterial or fungal pathogens


Prf control gene
bacterial or fungal pathogens


phytoalexins
bacterial or fungal pathogens


B-1,3-glucanase (antisense)
bacterial or fungal pathogens


AX + WIN-proteins
bacterial and fungal pathogens such as



Cercospora beticola


receptor kinase
bacterial or fungal pathogens


polypeptide having the effect of triggering
bacterial or fungal pathogens


a hypersensitivity reaction


systemic aquired resistance (SAR) genes
viral, bacterial, fungal and nematodal



pathogens


lytic protein
bacterial or fungal pathogens


lysozyme
bacterial or fungal pathogens


chitinases
bacterial or fungal pathogens


barnase
bacterial or fungal pathogens


glucanases
bacterial or fungal pathogens


double-strand ribonuclease
viruses such as, for example, BNYVV


envelope proteins
viruses such as, for example, BNYVV


17 kDa or 60 kDa protein
viruses such as, for example, BNYVV


nuclear inclusion proteins e.g. a or b or
viruses such as, for example, BNYVV


nucleoprotein


pseudoubiquitin
viruses such as, for example, BNYVV


replicase
viruses such as, for example, BNYVV


toxins of Bacillus thuringiensis, VIP 3,
Lepidoptera, aphids, mites, nematodes,


Bacilluscereus toxins, Photorabdus and
whitefly, beetles, root-flies


Xenorhabdus toxins


3-hydroxysteroid oxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


peroxidase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


aminopeptidase inhibitors, e.g. leucine
Lepidoptera, aphids, mites, nematodes,


aminopeptidase inhibitor
whitefly, beetles, root-flies


lectins
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


protease inhibitors, e.g. cystatin, patatin,
Lepidoptera, aphids, mites, nematodes,


CPTI, virgiferin
whitefly, beetles, root-flies


ribosome-inactivating protein
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


stilbene synthase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


HMG-CoA reductase
Lepidoptera, aphids, mites, nematodes,



whitefly, beetles, root-flies


hatching factor for cyst nematodes
cyst nematodes


barnase
nematodes, e.g. root-knot nematodes and



cyst nematodes


beet cyst nematode resistance site
cyst nematodes


CBI
root-knot nematodes


principles for preventing food uptake
nematodes, e.g. root-knot nematodes and


induced
root-cyst nematodes



















TABLE 2







AP
Control of









CrylA(a)
Adoxophyes spp.



CrylA(a)
Agrotis spp.



CrylA(a)
Alabama argiliaceae



CrylA(a)
Anticarsia gemmatalis



CrylA(a)
Chilo spp.



CrylA(a)
Clysia ambiguella



CrylA(a)
Crocidolomia binotalis



CrylA(a)
Cydia spp.



CrylA(a)
Diparopsis castanea



CrylA(a)
Earias spp.



CrylA(a)
Ephestia spp.



CrylA(a)
Heliothis spp.



CrylA(a)
Heliula undalis



CrylA(a)
Keiferia lycopersicella



CrylA(a)
Leucoptera scitella



CrylA(a)
Lithocollethis spp.



CrylA(a)
Lobesia botrana



CrylA(a)
Ostrinia nubilalis



CrylA(a)
Pandemis spp.



CrylA(a)
Pectinophora gossyp.



CrylA(a)
Phyllocnistis citrella



CrylA(a)
Pieris spp.



CrylA(a)
Plutella xylostella



CrylA(a)
Scirpophaga spp.



CrylA(a)
Sesamia spp.



CrylA(a)
Sparganothis spp.



CrylA(a)
Spodoptera spp.



CrylA(a)
Tortrix spp.



CrylA(a)
Trichoplusia ni



CrylA(a)
Agriotes spp.



CrylA(a)
Anthonomus grandis



CrylA(a)
Curculio spp.



CrylA(a)
Diabrotica balteata



CrylA(a)
Leptinotarsa spp.



CrylA(a)
Lissorhoptrus spp.



CrylA(a)
Otiorhynchus spp.



CrylA(a)
Aleurothrixus spp.



CrylA(a)
Aleyrodes spp.



CrylA(a)
Aonidiella spp.



CrylA(a)
Aphididea spp.



CrylA(a)
Aphis spp.



CrylA(a)
Bemisia tabaci



CrylA(a)
Empoasca spp.



CrylA(a)
Mycus spp.



CrylA(a)
Nephotettix spp.



CrylA(a)
Nilaparvata spp.



CrylA(a)
Pseudococcus spp.



CrylA(a)
Psylla spp.



CrylA(a)
Quadraspidiotus spp.



CrylA(a)
Schizaphis spp.



CrylA(a)
Trialeurodes spp.



CrylA(a)
Lyriomyza spp.



CrylA(a)
Oscinella spp.



CrylA(a)
Phorbia spp.



CrylA(a)
Frankliniella spp.



CrylA(a)
Thrips spp.



CrylA(a)
Scirtothrips aurantii



CrylA(a)
Aceria spp.



CrylA(a)
Aculus spp.



CrylA(a)
Brevipaipus spp.



CrylA(a)
Panonychus spp.



CrylA(a)
Phyllocoptruta spp.



CrylA(a)
Tetranychus spp.



CrylA(a)
Heterodera spp.



CrylA(a)
Meloidogyne spp.



CrylA(b)
Adoxophyes spp



CrylA(b)
Agrotis spp



CrylA(b)
Alabama argillaceae



CrylA(b)
Anticarsia gemmatalis



CrylA(b)
Chilo spp.



CrylA(b)
Ciysia ambiguella



CrylA(b)
Crocidolomia binotaiis



CrylA(b)
Cydia spp.



CrylA(b)
Diparopsis castanea



CrylA(b)
Earias spp.



CrylA(b)
Ephestia spp.



CrylA(b)
Heliothis spp.



CrylA(b)
Hellula undalis



CrylA(b)
Keiferia lycopersicella



CrylA(b)
Leucoptera scitella



CrylA(b)
Lithocollethis spp.



CrylA(b)
Lobesia botrana



CrylA(b)
Ostrinia nubilalis



CrylA(b)
Pandemis spp.



CrylA(b)
Pectinophora gossyp.



CrylA(b)
Phyllocnistis citrella



CrylA(b)
Pieris spp.



CrylA(b)
Plutelia xyiostella



CrylA(b)
Scirpophaga spp.



CrylA(b)
Sesamia spp.



CrylA(b)
Sparganothis spp.



CrylA(b)
Spodoptera spp.



CrylA(b)
Tortrix spp.



CrylA(b)
Trichoplusia ni



CrylA(b)
Agriotes spp.



CrylA(b)
Anthonomus grandis



CrylA(b)
Curculio spp.



CrylA(b)
Diabrotica balteata



CrylA(b)
Leptinotarsa spp.



CrylA(b)
Lissorhoptrus spp.



CrylA(b)
Otiorhynchus spp.



CrylA(b)
Aleurothrixus spp.



CrylA(b)
Aleyrodes spp.



CrylA(b)
Aonidiella spp.



CrylA(b)
Aphididae spp.



CrylA(b)
Aphis spp.



CrylA(b)
Bemisia tabaci



CrylA(b)
Empoasca spp.



CrylA(b)
Mycus spp.



CrylA(b)
Nephotettix spp.



CrylA(b)
Nilaparvata spp.



CrylA(b)
Pseudococcus spp.



CrylA(b)
Psylla spp.



CrylA(b)
Quadraspidiotus spp.



CrylA(b)
Schizaphis spp.



CrylA(b)
Trialeurodes spp.



CrylA(b)
Lyriomyza spp.



CrylA(b)
Oscinella spp.



CrylA(b)
Phorbia spp.



CrylA(b)
Frankliniella spp.



CrylA(b)
Thrips spp.



CrylA(b)
Scirtothrips aurantii



CrylA(b)
Aceria spp.



CrylA(b)
Aculus spp.



CrylA(b)
Brevipalpus spp.



CrylA(b)
Panonychus spp.



CrylA(b)
Phyllocoptruta spp.



CrylA(b)
Tetranychus spp.



CrylA(b)
Heterodera spp.



CrylA(b)
Meloidogyne spp.



CrylA(c)
Adoxophyes spp.



CrylA(c)
Agrotis spp.



CrylA(c)
Alabama argillaceae



CrylA(c)
Anticarsia gemmatalis



CrylA(c)
Chilo spp.



CrylA(c)
Ciysia ambiguella



CrylA(c)
Crocidolomia binotalis



CrylA(c)
Cydia spp.



CrylA(c)
Diparopsis castanea



CrylA(c)
Earias spp.



CrylA(c)
Ephestia spp.



CrylA(c)
Heliothis spp.



CrylA(c)
Hellula undalis



CrylA(c)
Keiferia lycopersicella



CrylA(c)
Leucoptera scitella



CrylA(c)
Lithocollethis spp.



CrylA(c)
Lobesia botrana



CrylA(c)
Ostrinia nubilalis



CrylA(c)
Pandemis spp.



CrylA(c)
Pectinophora gossypielia.



CrylA(c)
Phyllocnistis citrella



CrylA(c)
Pieris spp.



CrylA(c)
Plutella xyiostella



CrylA(c)
Scirpophaga spp.



CrylA(c)
Sesamia spp.



CrylA(c)
Sparganothis spp.



CrylA(c)
Spodoptera spp.



CrylA(c)
Tortrix spp.



CrylA(c)
Trichoplusia ni



CrylA(c)
Agriotes spp.



CrylA(c)
Anthonomus grandis



CrylA(c)
Curculio spp.



CrylA(c)
Diabrotica baiteata



CrylA(c)
Leptinotarsa spp.



CrylA(c)
Lissorhoptrus spp.



CrylA(c)
Otiorhynchus spp.



CrylA(c)
Aleurothrixus spp.



CrylA(c)
Aleyrodes spp.



CrylA(c)
Aonidiella spp.



CrylA(c)
Aphididae spp.



CrylA(c)
Aphis spp.



CrylA(c)
Bemisia tabaci



CrylA(c)
Empoasca spp.



CrylA(c)
Mycus spp.



CrylA(c)
Nephotettix spp.



CrylA(c)
Nilaparvata spp.



CrylA(c)
Pseudococcus spp.



CrylA(c)
Psylla spp.



CrylA(c)
Quadraspidiotus spp.



CrylA(c)
Schizaphis spp.



CrylA(c)
Trialeurodes spp.



CrylA(c)
Lyriomyza spp.



CrylA(c)
Oscinelia spp.



CrylA(c)
Phorbia spp.



CrylA(c)
Frankliniella spp.



CrylA(c)
Thrips spp.



CrylA(c)
Scirtothrips aurantii



CrylA(c)
Aceria spp.



CrylA(c)
Aculus spp.



CrylA(c)
Brevipalpus spp.



CrylA(c)
Panonychus spp.



CrylA(c)
Phyllocoptruta spp.



CrylA(c)
Tetranychus spp.



CrylA(c)
Heterodera spp.



CrylA(c)
Meloidogyne spp.



CryllA
Adoxophyes spp.



CryllA
Agrotis spp.



CryllA
Alabama argillaceae



CryllA
Anticarsia gemmatalis



CryllA
Chilo spp.



CryllA
Clysia ambiguella



CryllA
Crocidolomia binotalis



CryllA
Cydia spp.



CryllA
Diparopsis castanea



CryllA
Earias spp.



CryllA
Ephestia spp.



CryllA
Heliothis spp.



CryllA
Hellula undalis



CryllA
Keiferia lycopersicella



CryllA
Leucoptera scitella



CryllA
Lithocoliethis spp.



CryllA
Lobesia botrana



CryllA
Ostrinia nubilalis



CryllA
Pandemis spp.



CryllA
Pectinophora gossyp.



CryllA
Phyllocnistis citrella



CryllA
Pieris spp.



CryllA
Plutella xylostella



CryllA
Scirpophaga spp.



CryllA
Sesamia spp.



CryllA
Sparganothis spp.



CryllA
Spodoptera spp.



CryllA
Tortrix spp.



CryllA
Trichoplusia ni



CryllA
Agriotes spp.



CryllA
Anthonomus grandis



CryllA
Curculio spp.



CryllA
Diabrotica balteata



CryllA
Leptinotarsa spp.



CryllA
Lissorhoptrus spp.



CryllA
Otiorhynchus spp.



CryllA
Aleurothrixus spp.



CryllA
Aleyrodes spp.



CryllA
Aonidiella spp.



CryllA
Aphididae spp.



CryllA
Aphis spp.



CryllA
Bemisia tabaci



CryllA
Empoasca spp.



CryllA
Mycus spp.



CryllA
Nephotettix spp.



CryllA
Nilaparvata spp.



CryllA
Pseudococcus spp.



CryllA
Psyila spp.



CryllA
Quadraspidiotus spp.



CryllA
Schizaphis spp.



CryllA
Trialeurodes spp.



CryllA
Lyriomyza spp.



CryllA
Oscinella spp.



CryllA
Phorbia spp.



CryllA
Frankliniella spp.



CryllA
Thrips spp.



CryllA
Scirtothrips aurantii



CryllA
Aceria spp.



CryllA
Acutus spp.



CryllA
Brevipalpus spp.



CryllA
Panonychus spp.



CryllA
Phyllocoptruta spp.



CryllA
Tetranychus spp.



CryllA
Heterodera spp.



CryllA
Meloidogyne spp.



CrylllA
Adoxophyes spp.



CrylllA
Agrotis spp.



CrylllA
Alabama argiiiaceae



CrylllA
Anticarsia gemmataiis



CrylllA
Chilo spp.



CrylllA
Ciysia ambiguelia



CrylllA
Crocodolomia binotalis



CrylllA
Cydia spp.



CrylllA
Diparopsis castanea



CrylllA
Earias spp.



CrylllA
Ephestia spp.



CrylllA
Heliothis spp.



CrylllA
Hellula undalis



CrylllA
Keiferia lycopersicella



CrylllA
Leucoptera scitella



CrylllA
Lithocollethis spp.



CrylllA
Lobesia botrana



CrylllA
Ostrinia nubilalis



CrylllA
Pandemis spp.



CrylllA
Pectinophora gossyp.



CrylllA
Phyllocnistis citrella



CrylllA
Pieris spp.



CrylllA
Plutella xylostella



CrylllA
Scirpophaga spp.



CrylllA
Sesamia spp.



CrylllA
Sparganothis spp.



CrylllA
Spodoptera spp.



CrylllA
Tortrix spp.



CrylllA
Trichoplusia ni



CrylllA
Agriotes spp.



CrylllA
Anthonomus grandis



CrylllA
Curculio spp.



CrylllA
Diabrotica balteata



CrylllA
Leptinotarsa spp.



CrylllA
Lissorhoptrus spp.



CrylllA
Otiorhynchus spp.



CrylllA
Aleurothrixus spp.



CrylllA
Aleyrodes spp.



CrylllA
Aonidiella spp.



CrylllA
Aphididae spp.



CrylllA
Aphis spp.



CrylllA
Bemisia tabaci



CrylllA
Empoasca spp.



CrylllA
Mycus spp.



CrylllA
Nephotettix spp.



CrylllA
Nilaparvata spp.



CrylllA
Pseudococcus spp.



CrylllA
Psylla spp.



CrylllA
Quadraspidiotus spp.



CrylllA
Schizaphis spp.



CrylllA
Trialeurodes spp.



CrylllA
Lyriomyza spp.



CrylllA
Oscinella spp.



CrylllA
Phorbia spp.



CrylllA
Frankliniella spp.



CrylllA
Thrips spp.



CrylllA
Scirtothrips aurantii



CrylllA
Aceria spp.



CrylllA
Aculus spp.



CrylllA
Brevipalpus spp.



CrylllA
Panonychus spp.



CrylllA
Phyllocoptruta spp.



CrylllA
Tetranychus spp.



CrylllA
Heterodera spp.



CrylllA
Meloidogyne spp.



CrylllB2
Adoxophyes spp.



CrylllB2
Agrotis spp.



CrylllB2
Alabama argiilaceae



CrylllB2
Anticarsia gemmatalis



CrylllB2
Chilo spp.



CrylllB2
Clysia ambiguella



CrylllB2
Crocidolomia binotaiis



CrylllB2
Cydia spp.



CrylllB2
Diparopsis castanea



CrylllB2
Earias spp.



CrylllB2
Ephestia spp.



CrylllB2
Heliothis spp.



CrylllB2
Hellula undalis



CrylllB2
Keiferia lycopersicella



CrylllB2
Leucoptera sectelia



CrylllB2
Lithocollethis spp.



CrylllB2
Lobesia botrana



CrylllB2
Ostrinia nubilalis



CrylllB2
Pandemis spp.



CrylllB2
Pectinophora gossyp.



CrylllB2
Phyllocnistis citrella



CrylllB2
Pieris spp.



CrylllB2
Plutella xylostella



CrylllB2
Scirpophaga spp.



CrylllB2
Sesamia spp.



CrylllB2
Sparganothis spp.



CrylllB2
Spodoptera spp.



CrylllB2
Tortrix spp.



CrylllB2
Trichoplusia ni



CrylllB2
Agriotes spp.



CrylllB2
Anthonomus grandis



CrylllB2
Curculio spp.



CrylllB2
Diabrotica balteata



CrylllB2
Leptinotarsa spp.



CrylllB2
Lissorhoptrus spp.



CrylllB2
Otiorhynchus spp.



CrylllB2
Aleurothrixus spp.



CrylllB2
Aleyrodes spp.



CrylllB2
Aonidiella spp.



CrylllB2
Aphididae spp.



CrylllB2
Aphis spp.



CrylllB2
Bemisia tabaci



CrylllB2
Empoasca spp.



CrylllB2
Mycus spp.



CrylllB2
Nephotettix spp.



CrylllB2
Nilaparvata spp.



CrylllB2
Pseudococcus spp.



CrylllB2
Psylla spp.



CrylllB2
Quadraspidiotus spp.



CrylllB2
Schizaphis spp.



CrylllB2
Trialeurodes spp.



CrylllB2
Lyriornyza spp.



CrylllB2
Oscinella spp.



CrylllB2
Phorbia spp.



CrylllB2
Frankliniella spp.



CrylllB2
Thrips spp.



CrylllB2
Scirtothrips aurantii



CrylllB2
Aceria spp.



CrylllB2
Acutus spp.



CrylllB2
Brevipalpus spp.



CrylllB2
Panonychus spp.



CrylllB2
Phyllocoptruta spp.



CrylllB2
Tetranychus spp.



CrylllB2
Heterodera spp.



CrylllB2
Meloidogyne spp.



CytA
Adoxophyes spp.



CytA
Agrotis spp.



CytA
Alabama argiilaceae



CytA
Anticarsia gemmatalis



CytA
Chilo spp.



CytA
Clysia ambiguella



CytA
Crocidolomia binotaiis



CytA
Cydia spp.



CytA
Diparopsis castanea



CytA
Earias spp.



CytA
Ephestia spp.



CytA
Heliothis spp.



CytA
Hellula undalis



CytA
Keiferia lycopersicella



CytA
Leucoptera scitelia



CytA
Lithocollethis spp.



CytA
Lobesia botrana



CytA
Ostrinia nubilalis



CytA
Pandemis spp.



CytA
Pectinophora gossyp.



CytA
Phyllocnistis citrella



CytA
Pieris spp.



CytA
Plutella xylostella



CytA
Scirpophaga spp.



CytA
Sesamia spp.



CytA
Sparganothis spp.



CytA
Spodoptera spp.



CytA
Tortrix spp.



CytA
Trichoplusia ni



CytA
Agriotes spp.



CytA
Anthonomus grandis



CytA
Curculio spp.



CytA
Diabrotica balteata



CytA
Leptinotarsa spp.



CytA
Lissorhoptrus spp.



CytA
Otiorhynchus spp.



CytA
Aleurothrixus spp.



CytA
Aleyrodes spp.



CytA
Aonidielia spp.



CytA
Aphididae spp.



CytA
Aphis spp.



CytA
Bemisia tabaci



CytA
Empoasca spp.



CytA
Mycus spp.



CytA
Nephotettix spp.



CytA
Nilaparvata spp.



CytA
Pseudococcus spp.



CytA
Psylla spp.



CytA
Quadraspidiotus spp.



CytA
Schizaphis spp.



CytA
Trialeurodes spp.



CytA
Lyriomyza spp.



CytA
Oscinella spp.



CytA
Phorbia spp.



CytA
Frankliniella spp.



CytA
Thrips spp.



CytA
Scirtothrips aurantii



CytA
Aceria spp.



CytA
Acutus spp.



CytA
Brevipalpus spp.



CytA
Panonychus spp.



CytA
Phyllocoptruta spp.



CytA
Tetranychus spp.



CytA
Heterodera spp.



CytA
Meloidogyne spp.



VIP3
Adoxophyes spp.



VIP3
Agrotis spp.



VIP3
Alabama argillaceae



VIP3
Anticarsia gemmatalis



VIP3
Chilo spp.



VIP3
Clysia ambiguella



VIP3
Crocidolomia binotalis



VIP3
Cydia spp.



VIP3
Diparopsis castanea



VIP3
Earias spp.



VIP3
Ephestia spp.



VIP3
Heliothis spp.



VIP3
Hellula undalis



VIP3
Keiferia




lycopersicella



VIP3
Leucoptera scitella



VIP3
Lithocollethis spp.



VIP3
Lobesia botrana



VIP3
Ostrinia nubilalis



VIP3
Pandemis spp.



VIP3
Pectinophora gossyp.



VIP3
Phyllocnistis citrella



VIP3
Pieris spp.



VIP3
Piutella xylostella



VIP3
Scirpophaga spp.



VIP3
Sesamia spp.



VIP3
Sparganothis spp.



VIP3
Spodoptera spp.



VIP3
Tortrix spp.



VIP3
Trichoplusia ni



VIP3
Agriotes spp.



VIP3
Anthonomus grandis



VIP3
Curculio spp.



VIP3
Diabrotica balteata



VIP3
Leptinotarsa spp.



VIP3
Lissorhoptrus spp.



VIP3
Otiorhynchus spp.



VIP3
Aleurothrixus spp.



VIP3
Aleyrodes spp.



VIP3
Aonidiella spp.



VIP3
Aphididae spp.



VIP3
Aphis spp.



VIP3
Bemisia tabaci



VIP3
Empoasca spp.



VIP3
Mycus spp.



VIP3
Nephotettix spp.



VIP3
Niiaparvata spp.



VIP3
Pseudococcus spp.



VIP3
Psylla spp.



VIP3
Quadraspidiotus spp.



VIP3
Schizaphis spp.



VIP3
Trialeurodes spp.



VIP3
Lyriomyza spp.



VIP3
Oscinella spp.



VIP3
Phorbia spp.



VIP3
Frankliniella spp.



VIP3
Thrips spp.



VIP3
Scirtothrips aurantii



VIP3
Aceria spp.



VIP3
Acutus spp.



VIP3
Brevipalpus spp.



VIP3
Panonychus spp.



VIP3
Phyllocoptruta spp.



VIP3
Tetranychus spp.



VIP3
Heterodera spp.



VIP3
Meloidogyne spp.



GL
Adoxophyes spp.



GL
Agrotis spp.



GL
Alabama argillaceae



GL
Anticarsia gemmatalis



GL
Chilo spp.



GL
Clysia ambiguella



GL
Crocidolomia binotaiis



GL
Cydia spp.



GL
Diparopsis castanea



GL
Earias spp.



GL
Ephestia spp.



GL
Heliothis spp.



GL
Hellula undalis



GL
Keiferia lycopersicella



GL
Leucoptera scitella



GL
Lithocollethis spp.



GL
Lobesia botrana



GL
Ostrinia nubilalis



GL
Pandemis spp.



GL
Pectinophora gossyp.



GL
Phyliocnistis citrella



GL
Pieris spp.



GL
Plutella xylostella



GL
Scirpophaga spp.



GL
Sesamia spp.



GL
Sparganothis spp.



GL
Spodoptera spp.



GL
Tortrix spp.



GL
Trichoplusia ni



GL
Agriotes spp.



GL
Anthonomus grandis



GL
Curculio spp.



GL
Diabrotica balteata



GL
Leptinotarsa spp.



GL
Lissorhoptrus spp.



GL
Otiorhynchus spp.



GL
Aleurothrixus spp.



GL
Aleyrodes spp.



GL
Aonidiella spp.



GL
Aphididae spp.



GL
Aphis spp.



GL
Bemisia tabaci



GL
Empoasca spp.



GL
Mycus spp.



GL
Nephotettix spp.



GL
Nilaparvata spp.



GL
Pseudococcus spp.



GL
Psylia spp.



GL
Quadraspidiotus spp.



GL
Schizaphis spp.



GL
Trialeurodes spp.



GL
Lyriomyza spp.



GL
Oscinella spp.



GL
Phorbia spp.



GL
Frankliniella spp.



GL
Thrips spp.



GL
Scirtothrips aurantii



GL
Aceria spp.



GL
Aculus spp.



GL
Brevipalpus spp.



GL
Panonychus spp.



GL
Phyliocoptruta spp.



GL
Tetranychus spp.



GL
Heterodera spp.



GL
Meioidogyne spp.



PL
Adoxophyes spp.



PL
Agrotis spp.



PL
Alabama argillaceae



PL
Anticarsia gemmatalis



PL
Chilo spp.



PL
Clysia ambiguella



PL
Crocidolomia binotalis



PL
Cydia spp.



PL
Diparopsis castanea



PL
Earias spp.



PL
Ephestia spp.



PL
Heliothis spp.



PL
Hellula undaiis



PL
Keiferia lycopersicella



PL
Leucoptera scitella



PL
Lithocollethis spp.



PL
Lobesia botrana



PL
Ostrinia nubilalis



PL
Pandemis spp.



PL
Pectinophora gossyp.



PL
Phyllocnistis citrella



PL
Pieris spp.



PL
Plutella xylostella



PL
Scirpophaga spp.



PL
Sesamia spp.



PL
Sparganothis spp.



PL
Spodoptera spp.



PL
Tortrix spp.



PL
Trichoplusia ni



PL
Agriotes spp.



PL
Anthonomus grandis



PL
Curculio spp.



PL
Diabrotica balteata



PL
Leptinotarsa spp.



PL
Lissorhoptrus spp.



PL
Otiorhynchus spp.



PL
Aleurothrixus spp.



PL
Aleyrodes spp.



PL
Aonidiella spp.



PL
Aphididae spp.



PL
Aphis spp.



PL
Bemisia tabaci



PL
Empoasca spp.



PL
Mycus spp.



PL
Nephotettix spp.



PL
Nilaparvata spp.



PL
Pseudococcus spp.



PL
Psylla spp.



PL
Quadraspidiotus spp.



PL
Schizaphis spp.



PL
Trialeurodes spp.



PL
Lyriomyza spp.



PL
Oscinella spp.



PL
Phorbia spp.



PL
Frankliniella spp.



PL
Thrips spp.



PL
Scirtothrips auranii



PL
Aceria spp.



PL
Aculus spp.



PL
Brevipalpus spp.



PL
Panonychus spp.



PL
Phyllocoptruta spp.



PL
Tetranychus spp.



PL
Heterodera spp.



PL
Meloidogyne spp.



XN
Adoxophyes spp.



XN
Agrotis spp.



XN
Alabama argiliaceae



XN
Anticarsia gemmatalis



XN
Chilo spp.



XN
Clysia ambiguella



XN
Crocidolomia binotalis



XN
Cydia spp.



XN
Diparopsis castanea



XN
Earias spp.



XN
Ephestia spp.



XN
Heliothis spp.



XN
Helluia undaiis



XN
Keiferia lycopersicella



XN
Leucoptera scitella



XN
Lithocollethis spp.



XN
Lobesia botrana



XN
Ostrinia nubilalis



XN
Pandemis spp.



XN
Pectinophora gossyp.



XN
Phyllocnistis citrella



XN
Pieris spp.



XN
Plutella xylostella



XN
Scirpophaga spp.



XN
Sesamia spp.



XN
Sparganothis spp.



XN
Spodoptera spp.



XN
Tortrix spp.



XN
Trichoplusia ni



XN
Agriotes spp.



XN
Anthonomus grandis



XN
Curculio spp.



XN
Diabrotica balteata



XN
Leptinotarsa spp.



XN
Lissorhoptrus spp.



XN
Otiorhynchus spp.



XN
Aleurothrixus spp.



XN
Aleyrodes spp.



XN
Aonidiella spp.



XN
Aphididae spp.



XN
Aphis spp.



XN
Bemisia tabaci



XN
Empoasca spp.



XN
Mycus spp.



XN
Nephotettix spp.



XN
Nilaparvata spp.



XN
Pseudococcus spp.



XN
Psylla spp.



XN
Quadraspidiotus spp.



XN
Schizaphis spp.



XN
Trialeurodes spp.



XN
Lyriomyza spp.



XN
Oscinella spp.



XN
Phorbia spp.



XN
Frankliniella spp.



XN
Thrips spp.



XN
Scirtothrips aurantii



XN
Aceria spp.



XN
Aculus spp.



XN
Brevipalpus spp.



XN
Panonychus spp.



XN
Phyllocoptruta spp.



XN
Tetranychus spp.



XN
Heterodera spp.



XN
Meloidogyne spp.



Plnh.
Adoxophyes spp.



Plnh.
Agrotis spp.



Plnh.
Alabama argiliaceae



Plnh.
Anticarsia gemmatalis



Plnh.
Chilo spp.



Plnh.
Clysia ambiguella



Plnh.
Crocidolomia




binotalis



Plnh.
Cydia spp.



Plnh.
Diparopsis castanea



Plnh.
Earias spp.



Plnh.
Ephestia spp.



Plnh.
Heliothis spp.



Plnh.
Heliuia undalis



Plnh.
Keiferia lycopersicella



Plnh.
Leucoptera scitella



Plnh.
Lithocollethis spp.



Plnh.
Lobesia botrana



Plnh.
Ostrinia nubilalis



Plnh.
Pandemis spp.



Plnh.
Pectinophora gossyp.



Plnh.
Phyllocnistis citrelia



Plnh.
Pieris spp.



Plnh.
Plutella xylostella



Plnh.
Scirpophaga spp.



Plnh.
Sesamia spp.



Plnh.
Sparganothis spp.



Plnh.
Spodoptera spp.



Plnh.
Tortrix spp.



Plnh.
Trichoplusia ni



Plnh.
Agriotes spp.



Plnh.
Anthonomus grandis



Plnh.
Curculio spp.



Plnh.
Diabrotica balteata



Plnh.
Leptinotarsa spp.



Plnh.
Lissorhoptrus spp.



Plnh.
Otiorhynchus spp.



Plnh.
Aleurothrixus spp.



Plnh.
Aleyrodes spp.



Plnh.
Aonidiella spp.



Plnh.
Aphididae spp.



Plnh.
Aphis spp.



Plnh.
Bemisia tabaci



Plnh.
Empoasca spp.



Plnh.
Mycus spp.



Plnh.
Nephotettix spp.



Plnh.
Nilaparvata spp.



Plnh.
Pseudococcus spp.



Plnh.
Psylla spp.



Plnh.
Quadraspidiotus spp.



Plnh.
Schizaphis spp.



Plnh.
Trialeurodes spp.



Plnh.
Lyriomyza spp.



Plnh.
Oscinella spp.



Plnh.
Phorbia spp.



Plnh.
Frankliniella spp.



Plnh.
Thrips spp.



Plnh.
Scirtothrips aurantii



Plnh.
Aceria spp.



Plnh.
Acutus spp.



Plnh.
Brevipalpus spp.



Plnh.
Panonychus spp.



Plnh.
Phyllocoptruta spp.



Plnh.
Tetranychus spp.



Plnh.
Heterodera spp.



Plnh.
Meloidogyne spp.



PLec.
Adoxophyes spp.



PLec.
Agrotis spp.



PLec.
Alabama argillaceae



PLec.
Anticarsia gemmatalis



PLec.
Chilo spp.



PLec.
Clysia ambiguella



PLec.
Crocidolomia binotalis



PLec.
Cydia spp.



PLec.
Diparopsis castanea



PLec.
Earias spp.



PLec.
Ephestia spp.



PLec.
Heliothis spp.



PLec.
Hellula undalis



PLec.
Keiferia lycopersicella



PLec.
Leucoptera scitella



PLec.
Lithocollethis spp.



PLec.
Lobesia botrana



PLec.
Ostrinia nubilalis



PLec.
Pandemis spp.



PLec.
Pectinophora gossyp.



PLec.
Phyllocnistis citrella



PLec.
Pieris spp.



PLec.
Plutella xylostella



PLec.
Scirpophaga spp.



PLec.
Sesamia spp.



PLec.
Sparganothis spp.



PLec.
Spodoptera spp.



PLec.
Tortrix spp.



PLec.
Trichoplusia ni



PLec.
Agriotes spp.



PLec.
Anthonomus grandis



PLec.
Curculio spp.



PLec.
Diabrotica balteata



PLec.
Leptinotarsa spp.



PLec.
Lissorhoptrus spp.



PLec.
Otiorhynchus spp.



PLec.
Aleurothrixus spp.



PLec.
Aleyrodes spp.



PLec.
Aonidiella spp.



PLec.
Aphididae spp.



PLec.
Aphis spp.



PLec.
Bemisia tabaci



PLec.
Empoasca spp.



PLec.
Mycus spp.



PLec.
Nephotettix spp.



PLec.
Nilaparvata spp.



PLec.
Pseudococcus spp.



PLec.
Psylia spp.



PLec.
Quadraspidiotus spp.



PLec.
Schizaphis spp.



PLec.
Trialeurodes spp.



PLec.
Lyriomyza spp.



PLec.
Oscinella spp.



PLec.
Phorbia spp.



PLec.
Frankliniella spp.



PLec.
Thrips spp.



PLec.
Scirtothnps aurantii



PLec.
Aceria spp.



PLec.
Aculus spp.



PLec.
Brevipalpus spp.



PLec.
Panonychus spp.



PLec.
Phyllocoptruta spp.



PLec.
Tetranychus spp.



PLec.
Heterodera spp.



PLec.
Meloidogyne spp.



Aggl.
Adoxophyes spp.



Aggl.
Agrotis spp.



Aggl.
Alabama




argillaceae



Aggl.
Anticarsia gemmatalis



Aggl.
Chilo spp.



Aggl.
Clysia ambiguella



Aggl.
Crocidolomia




binotalis



Aggl.
Cydia spp.



Aggl.
Diparopsis




castanea



Aggl.
Earias spp.



Aggl.
Ephestia spp.



Aggl.
Heliothis spp.



Aggl.
Hellula undalis



Aggl.
Keiferia




lycopersicella



Aggl.
Leucoptera scitella



Aggl.
Lithocollethis spp.



Aggl.
Lobesia botrana



Aggl.
Ostrinia nubilalis



Aggl.
Pandemis spp.



Aggl.
Pectinophora




gossyp.



Aggl.
Phyllocnistis citrella



Aggl.
Pieris spp.



Aggl.
Plutiia xylostella



Aggl.
Scirpophaga spp.



Aggl.
Sesamia spp.



Aggl.
Sparganothis spp.



Aggl.
Spodoptera spp.



Aggl.
Tortrix spp.



Aggl.
Trichoplusia ni



Aggl.
Agriotes spp.



Aggl.
Anthonomus grandis



Aggl.
Curculio spp.



Aggl.
Diabrotica balteata



Aggl.
Leptinotarsa spp.



Aggl.
Lissorhoptrus spp.



Aggl.
Otiorhynchus spp.



Aggl.
Aleurothrixus spp.



Aggl.
Aleyrodes spp.



Aggl.
Aonidiella spp.



Aggl.
Aphididae spp.



Aggl.
Aphis spp.



Aggl.
Bemisia tabaci



Aggl.
Empoasca spp.



Aggl.
Mycus spp.



Aggl.
Nephotettix spp.



Aggl.
Nilaparvata spp.



Aggl.
Pseudococcus spp.



Aggl.
Psylla spp.



Aggl.
Quadraspidiotus spp.



Aggl.
Schizaphis spp.



Aggl.
Trialeurodes spp.



Aggl.
Lyriomyza spp.



Aggl.
Oscinella spp.



Aggl.
Phorbia spp.



Aggl.
Frankliniella spp.



Aggl.
Thrips spp.



Aggl.
Scirtothrips auranti



Aggl.
Aceria spp.



Aggl.
Aculus spp.



Aggl.
Brevipalpus spp.



Aggl.
Panonychus spp.



Aggl.
Phyllocoptruta spp



Aggl.
Tetranychus spp.



Aggl.
Heterodera spp.



Aggl.
Meloidogyne spp.



CO
Adoxophyes spp.



CO
Agrotis spp.



CO
Alabama argiliaceae



CO
Anticarsia gemmatalis



CO
Chilo spp.



CO
Ciysia ambiguella



CO
Crocidolomia binotalis



CO
Cydia spp.



CO
Diparopsis castanea



CO
Earias spp.



CO
Ephestia spp.



CO
Heliothis spp.



CO
Hellula undalis



CO
Keiferia lycopersicella



CO
Leucoptera scitella



CO
Lithocollethis spp.



CO
Lobesia botrana



CO
Ostrinia nubilalis



CO
Pandemis spp.



CO
Pectinophora gossyp.



CO
Phyllocnistis citrella



CO
Pieris spp.



CO
Plutella xylostella



CO
Scirpophaga spp.



CO
Sesamia spp.



CO
Sparganothis spp.



CO
Spodoptera spp.



CO
Tortrix spp.



CO
Trichoplusia ni



CO
Agriotes spp.



CO
Anthonomus grandis



CO
Curculio spp.



CO
Diabrotica balteata



CO
Leptinotarsa spp.



CO
Lissorhoptrus spp.



CO
Otiorhynchus spp.



CO
Aleurothrixus spp.



CO
Aleyrodes spp.



CO
Aonidielia spp.



CO
Aphididae spp.



CO
Aphis spp.



CO
Bemisia tabaci



CO
Empoasca spp.



CO
Mycus spp.



CO
Nephotettix spp.



CO
Nilaparvata spp.



CO
Pseudococcus spp.



CO
Psylla spp.



CO
Quadraspidiotus spp.



CO
Schizaphis spp.



CO
Trialeurodes spp.



CO
Lyriomyza spp.



CO
Oscinella spp.



CO
Phorbia spp.



CO
Frankliniella spp.



CO
Thrips spp.



CO
Scirtothrips aurantii



CO
Aceria spp.



CO
Acutus spp.



CO
Brevipalpus spp.



CO
Panonychus spp.



CO
Phyllocoptruta spp.



CO
Tetranychus spp.



CO
Heterodera spp.



CO
Meloidogyne spp.



CH
Adoxophyes spp.



CH
Agrotis spp.



CH
Alabama argillaceae



CH
Anticarsia




gemmatalis



CH
Chilo spp.



CH
Clysia ambiguella



CH
Crocidolomia binotalis



CH
Cydia spp.



CH
Diparopsis castanea



CH
Earias spp.



CH
Ephestia spp.



CH
Heliothis spp.



CH
Hellula undalis



CH
Keiferia lycopersicella



CH
Leucoptera scitella



CH
Lithocollethis spp.



CH
Lobesia botrana



CH
Ostrinia nubilalis



CH
Pandemis spp.



CH
Pectinophora gossyp.



CH
Phyllocnistis citrella



CH
Pieris spp.



CH
Plutella xylostella



CH
Scirpophaga spp.



CH
Sesamia spp.



CH
Sparganothis spp.



CH
Spodoptera spp.



CH
Tortrix spp.



CH
Trichoplusia ni



CH
Agriotes spp.



CH
Anthonomus




grandis



CH
Curculio spp.



CH
Diabrotica balteata



CH
Leptinotarsa spp.



CH
Lissorhoptrus spp.



CH
Otiorhynohus spp.



CH
Aleurothrixus spp.



CH
Aleyrodes spp.



CH
Aonidiella spp.



CH
Aphididae spp.



CH
Aphis spp.



CH
Bemisia tabaci



CH
Empoasca spp.



CH
Mycus spp.



CH
Nephotettix spp.



CH
Nilaparvata spp.



CH
Pseudococcus spp.



CH
Psylla spp.



CH
Quadraspidiotus spp.



CH
Schizaphis spp.



CH
Trialeurodes spp.



CH
Lyriomyza spp.



CH
Oscinella spp.



CH
Phorbia spp.



CH
Frankliniella spp.



CH
Thrips spp.



CH
Scirtothrips aurantii



CH
Aceria spp.



CH
Aculus spp.



CH
Brevipalpus spp.



CH
Panonychus spp.



CH
Phyllocoptruta spp.



CH
Tetranychus spp.



CH
Heterodera spp.



CH
Meloidogyne spp.



SS
Adoxophyes spp.



SS
Agrotis spp.



SS
Alabama argillaceae



SS
Anticarsia gemmatalis



SS
Chilo spp.



SS
Clysia ambiguella



SS
Crocidolomia binotalis



SS
Cydia spp.



SS
Diparopsis castanea



SS
Earias spp.



SS
Ephestia spp.



SS
Heliothis spp.



SS
Hellula undalis



SS
Keiferia lycopersicella



SS
Leucoptera scitella



SS
Lithocollethis spp.



SS
Lobesia botrana



SS
Ostrinia nubilalis



SS
Pandemis spp.



SS
Pectinophora gossyp.



SS
Phyllocnistis citrella



SS
Pieris spp.



SS
Plutella xylostella



SS
Scirpophaga spp.



SS
Sesamia spp.



SS
Sparganothis spp.



SS
Spodoptera spp.



SS
Tortrix spp.



SS
Trichopiusia ni



SS
Agriotes spp.



SS
Anthonomus grandis



SS
Curculio spp.



SS
Diabrotica balteata



SS
Leptinotarsa spp.



SS
Lissorhoptrus spp.



SS
Otiorhynchus spp.



SS
Aleurothrixus spp.



SS
Aleyrodes spp.



SS
Aonidielia spp.



SS
Aphididae spp.



SS
Aphis spp.



SS
Bemisia tabaci



SS
Empoasca spp.



SS
Mycus spp.



SS
Nephotettix spp.



SS
Nilaparvata spp.



SS
Pseudococcus spp.



SS
Psylla spp.



SS
Quadraspidiotus spp.



SS
Schizaphis spp.



SS
Trialeurodes spp.



SS
Lyriomyza spp.



SS
Oscinella spp.



SS
Phorbia spp.



SS
Frankliniella spp.



SS
Thrips spp.



SS
Scirtothrips aurantii



SS
Aceria spp.



SS
Aculus spp.



SS
Brevipalpus spp.



SS
Panonychus spp.



SS
Phyllocoptruta spp.



SS
Tetranychus spp.



SS
Heterodera spp.



SS
Meloidogyne spp.



HO
Adoxophyes spp.



HO
Agrotis spp.



HO
Alabama argillaceae



HO
Anticarsia gemmatalis



HO
Chilo spp.



HO
Clysia ambiguella



HO
Crocidolomia binotalis



HO
Cydia spp.



HO
Diparopsis castanea



HO
Earias spp.



HO
Ephestia spp.



HO
Heliothis spp.



HO
Hellula undalis



HO
Keiferia lycopersicella



HO
Leucoptera scitella



HO
Lithocollethis spp.



HO
Lobesia botrana



HO
Ostrinia nubilalis



HO
Pandemis spp.



HO
Pectinophora gossypiella



HO
Phyllocnistis citrella



HO
Pieris spp.



HO
Plutella xylostella



HO
Scirpophaga spp.



HO
Sesamia spp.



HO
Sparganothis spp.



HO
Spodoptera spp.



HO
Tortrix spp.



HO
Trichoplusia ni



HO
Agriotes spp.



HO
Anthonomus grandis



HO
Curculio spp.



HO
Diabrotica balteata



HO
Leptinotarsa spp.



HO
Lissorhoptrus spp.



HO
Otiorhynchus spp.



HO
Aleurothrixus spp.



HO
Aleyrodes spp.



HO
Aonidiella spp.



HO
Aphididae spp.



HO
Aphis spp.



HO
Bemisia tabaci



HO
Empoasca spp.



HO
Mycus spp.



HO
Nephotettix spp.



HO
Nilaparvata spp.



HO
Pseudococcus spp.



HO
Psylla spp.



HO
Quadraspidiotus spp.



HO
Schizaphis spp.



HO
Trialeurodes spp.



HO
Lyriomyza spp.



HO
Oscinella spp.



HO
Phorbia spp.



HO
Frankliniella spp.



HO
Thrips spp.



HO
Scirtothrips aurantii



HO
Aceria spp.



HO
Acutus spp.



HO
Brevipalpus spp.



HO
Panonychus spp.



HO
Phyllocoptruta spp.



HO
Tetranychus spp.



HO
Heterodera spp.



HO
Meloidogyne spp.







In the table, the following abbreviations were used:



active principle of the transgenic plant: AP



Photorhabdus luminescens: PL



Xenorhabdus nematophilus: XN



proteinase inhibitors: Plnh.



plant lectins PLec.



agglutinines: Aggl.



3-hydroxysteroid oxidase: HO



cholesterol oxidase: CO



chitinase: CH



glucanase: GL



stilbene synthase: SS

















TABLE 3







Principle
Tolerance to
Plant









ALS
sulphonylurea compounds etc.***
cotton



ALS
sulphonylurea compounds etc.***
rice



ALS
sulphonylurea compounds etc.***
Brassica



ALS
sulphonylurea compounds etc.***
potatoes



ALS
sulphonylurea compounds etc.***
tomatoes



ALS
sulphonylurea compounds etc.***
pumpkin



ALS
sulphonylurea compounds etc.***
soya beans



ALS
sulphonylurea compounds etc.***
maize



ALS
sulphonylurea compounds etc.***
wheat



ALS
sulphonylurea compounds etc.***
pome fruit



ALS
sulphonylurea compounds etc.***
stone fruit



ALS
sulphonylurea compounds etc.***
citrus fruit



ACCase
+++
cotton



ACCase
+++
rice



ACCase
+++
Brassica



ACCase
+++
potato



ACCase
+++
tomatoes



ACCase
+++
pumpkin



ACCase
+++
soya beans



ACCase
+++
maize



ACCase
+++
wheat



ACCase
+++
pome fruit



ACCase
+++
stone fruit



ACCase
+++
citrus fruit



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
cotton




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
rice




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
Brassica




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
potatoes




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
tomatoes




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
pumpkin




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
soya beans




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
maize




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
wheat




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
pome fruit




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
stone fruit




mesotrione



HPPD
isoxaflutole, isoxachlortole, sulcotrione,
citrus fruit




mesotrione



nitrilase
bromoxynil, loxynil
cotton



nitrilase
bromoxynil, loxynil
rice



nitrilase
bromoxynil, loxynil
Brassica



nitrilase
bromoxynil, loxynil
potatoes



nitrilase
bromoxynil, loxynil
tomatoes



nitrilase
bromoxynil, loxynil
pumpkin



nitrilase
bromoxynil, loxynil
soya beans



nitrilase
bromoxynil, loxynil
maize



nitrilase
bromoxynil, loxynil
wheat



nitrilase
bromoxynil, loxynil
pome fruit



nitrilase
bromoxynil, loxynil
stone fruit



nitrilase
bromoxynil, loxynil
citrus fruit



IPS
chloroactanilides &&&
cotton



IPS
chloroactanilides &&&
rice



IPS
chloroactanilides &&&
Brassica



IPS
chloroactanilides &&&
potatoes



IPS
chloroactanilides &&&
tomatoes



IPS
chloroactanilides &&&
pumpkin



IPS
chloroactanilides &&&
soya beans



IPS
chloroactanilides &&&
maize



IPS
chloroactanilides &&&
wheat



IPS
chloroactanilides &&&
pome fruit



IPS
chloroactanilides &&&
stone fruit



IPS
chloroactanilides &&&
citrus fruit



HOM
2,4-D, mecoprop-P
cotton



HOM
2,4-D, mecoprop-P
rice



HOM
2,4-D, mecoprop-P
Brassica



HOM
2,4-D, mecoprop-P
potatoes



HOM
2,4-D, mecoprop-P
tomatoes



HOM
2,4-D, mecoprop-P
pumpkin



HOM
2,4-D, mecoprop-P
soya beans



HOM
2,4-D, mecoprop-P
maize



HOM
2,4-D, mecoprop-P
wheat



HOM
2,4-D, mecoprop-P
pome fruit



HOM
2,4-D, mecoprop-P
stone fruit



HOM
2,4-D, mecoprop-P
citrus fruit



PROTOX
Protox inhibitors ///
cotton



PROTOX
Protox inhibitors ///
rice



PROTOX
Protox inhibitors ///
Brassica



PROTOX
Protox inhibitors ///
potatoes



PROTOX
Protox inhibitors ///
tomatoes



PROTOX
Protox inhibitors ///
pumpkin



PROTOX
Protox inhibitors ///
soya beans



PROTOX
Protox inhibitors ///
maize



PROTOX
Protox inhibitors ///
wheat



PROTOX
Protox inhibitors ///
pome fruit



PROTOX
Protox inhibitors ///
stone fruit



PROTOX
Protox inhibitors ///
citrus fruit



EPSPS
glyphosate and/or sulphosate
cotton



EPSPS
glyphosate and/or sulphosate
rice



EPSPS
glyphosate and/or sulphosate
Brassica



EPSPS
glyphosate and/or sulphosate
potatoes



EPSPS
glyphosate and/or sulphosate
tomatoes



EPSPS
glyphosate and/or sulphosate
pumpkin



EPSPS
glyphosate and/or sulphosate
soya beans



EPSPS
glyphosate and/or sulphosate
maize



EPSPS
glyphosate and/or sulphosate
wheat



EPSPS
glyphosate and/or sulphosate
pome fruit



EPSPS
glyphosate and/or sulphosate
stone fruit



EPSPS
glyphosate and/or sulphosate
citrus fruit



GS
gluphosinate and/or bialaphos
cotton



GS
gluphosinate and/or bialaphos
rice



GS
gluphosinate and/or bialaphos
Brassica



GS
gluphosinate and/or bialaphos
potatoes



GS
gluphosinate and/or bialaphos
tomatoes



GS
gluphosinate and/or bialaphos
pumpkin



GS
gluphosinate and/or bialaphos
soya beans



GS
gluphosinate and/or bialaphos
maize



GS
gluphosinate and/or bialaphos
wheat



GS
gluphosinate and/or bialaphos
pome fruit



GS
gluphosinate and/or bialaphos
stone fruit



GS
gluphosinate and/or bialaphos
citrus fruit







Abbreviations:



acetyl-CoA carboxylase: ACCase



acetolactate synthase: ALS



hydroxyphenylpyruvate dioxygenase: HPPD



inhibition of protein synthesis: IPS



hormone imitation: HO



glutamine synthetase: GS



protoporphyrinogen oxidase: PROTOX



5-enolpyruvyl-3-phosphoshikimate synthase: EPSPS



***included are sulphonylurea compounds, imidazolinones, triazolopyrimidines, dimethoxypyrimidines and N-acylsulphonamides: sulphonylurea compounds such as chlorsulfuron, chlorimuron, ethamethsulfuron, metsulfuron, primisulfuron, prosulfuron, triasulfuron, cinosulfuron, trifusulfuron, oxasulfuron, bensulfuron, tribenuron, ACC 322140, fluzasulfuron, ethoxysulfuron, fluzadsulfuron, nicosulfuron, rimsulfuron, thifensulfuron, pyrazosulfuron, clopyrasulfuron, NC 330, azimsulfuron, imazosulfuron, sulfosulfuron, amidosulfuron, flupyrsulfuron, CGA 362622 imidazolinones such as imazamethabenz, imazaquin, imazamethypyr, imazethapyr, imazapyr and imazamox; triazolopyrimidines such as DE 511, flumetsulam and chloransulam; dimethoxypyrimidines such as, for example, pyrithiobac, pyriminobac, bispyribac and pyribenzoxim.



+++ Tolerance to diclofop-methyl, fluazifop-P-butyl, haloxyfop-P-methyl, haloxyfop-P-ethyl, quizalafop-P-ethyl, clodinafop-propargyl, fenoxaprop-ethyl, tepraloxydim, alloxydim, sethoxydim, cycloxydim, cloproxydim, tralkoxydim, butoxydim, caloxydim, clefoxydim, clethodim.



&&& chloroacetanilides such as, for example, alachlor, acetochlor, dimethenamid



/// Protox inhibitors: for example diphenyl ethers such as, for example, acifluorfen, aclonifen, bifenox, chlornitrofen, ethoxyfen, fluoroglycofen, fomesafen, lactofen, oxyfluorfen; imides such as, for example, azafenidin, carfentrazone-ethyl, cinidon-ethyl, flumiclorac-pentyl, flumioxazin, fluthiacet-methyl, oxadiargyl, oxadiazon, pentoxazone, sulfentrazone, imides and other compounds such as, for example, flumipropyn, flupropacil, nipyraclofen and thidiazimin; and also fluazola and pyraflufen-ethyl.













TABLE 4







List of examples of transgenic plants having modified properties:








Transgenic plants
Transgenically modified properties





Dianthus caryophyllus (carnation)
Longer-lasting as a result of reduced ethylene


line 66
accumulation owing to the expression of ACC


[Florigene Pty. Ltd.]
synthase; tolerant to sulphonylurea herbicides


Dianthus caryophyllus (carnation)
Modified flower colour; tolerant to sulphonyl-


lines 4, 11, 15, 16
urea herbicides


[Florigene Pty. Ltd.]


Dianthus caryophyllus (carnation)
Modified flower colour; tolerant to sulphonyl-


lines 959A, 988A, 1226A, 1351A, 1363A,
urea herbicides


1400A


[Florigene Pty. Ltd.]


Brassica napus (Argentine oilseed rape)
Modified fatty acid content in the seeds


lines 23-18-17, 23-198


[Monsanto Company]


Zea mays L. (maize)
Elevated lysine content


lines REN-ØØØ38-3 (LY038)


[Monsanto Company]


Zea mays L. (maize)
Elevated lysine content, resistant to the corn


lines REN-ØØØ38-3, MON-ØØ81Ø-6
borer


(MON-ØØ81Ø-6 × LY038)


[Monsanto Company]


Cucumis melo (melon)
Delayed maturity as a result of the expression of


lines A, B
S-adenosylmethionine hydrolase


[Agritope Inc.]


Carica papaya (papaya)
Resistant to the papaya ring spot virus (PRSV)


lines 55-1/63-1


[Cornell University]


Solanum tuberosum L. (potato)
Resistant to the Colorado beetle and the potato


lines RBMT21-129, RBMT21-350, RBMT22-
leaf roll virus (PLRV)


082


[Monsanto Company]


Solanum tuberosum L. (potato)
Resistant to the Colorado beetle and the potato


lines RBMT15-101, SEMT15-02, SEMT15-15
virus Y (PVY)


[Monsanto Company]


Glycine max L. (soya bean)
Modified fatty acid content in the seeds, in


lines DD-Ø26ØØ5-3 (G94-1, G94-19, G168)
particular elevated oleic acid content


[DuPont Canada Agricultural Products]


Glycine max L. (soya bean)
Modified fatty acid content in the seeds, in


lines OT96-15
particular reduced linolenic acid content


[Agriculture & Agri-Food Canada]


Cucurbita pepo (pumpkin)
Resistant to viral infections, watermelon mosaic


line ZW20
virus (WMV) 2 and zucchini yellow mosaic


[Upjohn (USA); Seminis Vegetable Inc.
virus (ZYMV)


(Canada)]


Cucurbita pepo (pumpkin)
Resistance to viral infections, cucumber mosaic


line CZW-3
virus (CMV), watermelon mosaic virus (WMV)


[Asgrow (USA); Seminis Vegetable Inc.
2 and zucchini yellow mosaic virus (ZYMV)


(Canada)]


Nicotiana tabacum L. (tobacco)
Reduced nicotine content


line Vector 21-41


[Vector Tobacco]


Lycopersicon esculentum (tomato)
Longer lasting as a result of reduced ethylene


line 1345-4
accumulation owing to the expression of ACC


[DNA Plant Technology]
synthase


Lycopersicon esculentum (tomato)
Delayed maturity as a result of the expression of


line 35 1 N
S-adenosylmethionine hydrolase


[Agritope Inc.]


Lycopersicon esculentum (tomato)
Delayed maturity as a result of the expression of


line CGN-89322-3 (8338)
ACCd


[Monsanto Company]


Lycopersicon esculentum (tomato)
Delayed softening as a result of a reduced


lines B, Da, F
expression of polygalacturonase


[Zeneca Seeds]


Lycopersicon esculentum (tomato)
Delayed softening as a result of a reduced


line CGN-89564-2 (FLAVR SAVR)
expression of polygalacturonase


[Calgene Inc.]









EXAMPLES
The invention is illustrated in more detail by the non-limiting examples below.
Example 1
Individually potted transgenic cotton plants with Lepidoptera resistance and herbicide resistance (cultivar DP444 BG/RR) are treated in 2 replications against larvae of the cotton bollworm (Heliotizis armigera). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.
Example 2
Pots with in each case 5 transgenic maize plants having Lepidoptera resistance and herbicide resistance (cultivar SGI1890 H×X SGI1847) are treated in 2 replications against the armyworm (Spodoptera frugiperda). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.
Example 3
Pots with in each case 5 transgenic maize plants having herbicide resistance (cultivar FR1064LL X FR2108) are treated in 2 replications against the armyworm (Spodoptera frugiperda). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.
Example 4
Aphis gossypii on Cotton
Individually potted transgenic cotton plants with Lepidoptera resistance and herbicide resistance (cultivar DP444 BG/RR), which are populated by a mixed population of the cotton aphid (Aphis gossypii) are treated by dip application with the respective active compound.
After the desired period of time, the kill in % is determined. 100% means that all aphids have been killed; 0% means that none of the aphids have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.















Concentration
Kill rate


Active compound
in ppm
in % after 1d





I-5
0.8
40


DP 444 BG/RR

0


Cry1Ac&cp4 epsps












found*
calc.**


I-5 + DP 444 BG/RR
0.8
55
40


according to the invention













Concentration
Kill rate


Active compound
in ppm
in % after 6d





I-4
0.8
15


DP 444 BG/RR

0


Cry1Ac&cp4 epsps












found*
calc.**


I-4 + DP 444 BG/RR
0.8
60
15


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 5
Heliothis armigera on Cotton
Individually potted transgenic cotton plants with Lepidoptera resistance and herbicide resistance (cultivar DP444 BG/RR) are treated in 2 replications against larvae of the cotton bollworm (Heliothis armigera). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.













Concentration
Kill rate


Active compound
in ppm
in % after 4d

















I-4
100
0


I-6
20
0


DP 444 BG/RR

0


Cry1Ac&cp4 epsps












found*
calc.**


I-4 + DP 444 BG/RR
100
20
0


according to the invention


I-6 + DP 444 BG/RR
20
30
0


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 6
Spodoptera frugiperda on Cotton
Individually potted transgenic cotton plants with Lepidoptera resistance and herbicide resistance (cultivar DP444 BG/RR) are treated in 2 replications against the armyworm (Spodoptera frugiperda). Application is by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.















Concentration
Kill rate


Active compound
in ppm
in % after 4d





I-5
20
0


DP 444 BG/RR

0


Cry1Ac&cp4 epsps












found*
calc.**


I-5 + DP 444 BG/RR
20
60
0


according to the invention













Concentration
Kill rate


Active compound
in ppm
in % after 6d





I-6
100
20


DP 444 BG/RR

0


Cry1Ac&cp4 epsps












found*
calc.**


I-4 + DP 444 BG/RR
100
40
20


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 7
Diabrotica balteata on Maize
Pots with in each case 5 transgenic maize plants having Coleoptera, Lepidoptera and/or herbicide resistance (cultivars LH244RR×LH324 and HCL 201CRW2RR2×LH 324) are treated in 2 replications against larvae of the banded cucumber beetle (Diabrotica balteata). Application is carried out by drench application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all beetle larvae have been killed; 0% means that none of the beetle larvae have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.













Concentration
Kill rate


Active compound
in ppm
in % after 10d

















I-5
100
45


VSN-RR

0


Cp4epsps


HCL201CRW2RR2 × LH324

0


Cry3Bb1&Cp4epsps












found*
calc.**


I-5 + VSN-RR
100
60
45


according to the invention


I-5 + HCL201CRW 2RR2 ×
100
90
45


LH324


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 8
Spodoptera exigua on Maize
Pots with in each case 5 transgenic maize plants having Coleoptera, Lepidoptera and/or herbicide resistance (cultivars LH332RR×LH324BT, LH244RR×LH324, HC33CRW×LH287BTCRW and TR47×TR 7322 BT) are treated in 2 replications against larvae of the beet armyworm (Spodoptera exigua). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.













Concentration
Kill rate


Active compound
in ppm
in % after 4d

















I-4
100
0


I-10
100
10


I-6
100
0


VSN-RR BT

31.7


Cry1Ab&Cp4epsps


VSN-RR

0


Cp4epsps


VSN-BTCRW

15


Cry1Ab&Cry3Bb1


VSN-BT

0


Bt MON 810












found*
calc.**


I-4 + VSN-RR BT
100
100
31.7


according to the invention


I-4 + VSN-RR
100
90
38.53


according to the invention


I-10 + VSN-RR BT
100
100
73


according to the invention


I-6 + VSN-RR BT
100
65
31.7


according to the invention


I-6 + VSN-BTCRW
100
65
15


according to the invention


I-6 + VSN-BT
100
35
0


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 9
Spodoptera frugiperda on Maize
Pots with in each case 5 transgenic maize plants having Coleoptera, Lepidoptera and/or herbicide resistance (cultivars HC33CRW×LH287BTCRW, TR47×TR 7322 BT) are treated in 2 replications against the armyworm (Spodoptera frugiperda). Application is carried out by dip application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.















Concentration
Kill rate


Active compound
in ppm
in % after 1d





I-5
100
0


VSN-BTCRW

0


Cry1Ab&Cry3Bb1












found*
calc.**


I-5 + VSN-BTCRW
100
20
 0


according to the invention













Concentration
Kill rate


Active compound
in ppm
in % after 4d





I-4
100
0


I-5
100
10


I-6
100
0


VSN-BTCRW

60


Cry1Ab&Cry3Bb1


VSN-BT

70


Bt MON 810












found*
calc.**


I-4 + VSN-BTCRW
100
80
60


according to the invention


I-5 + VSN-BTCRW
100
100
64


according to the invention


I-5 + VSN-BT
100
100
73


according to the invention


I-6 + VSN-BTCRW
100
100
60


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula






Example 10
Spodoptera frugiperda on Maize (Drench Application)
Pots with in each case 5 transgenic maize plants having Coleoptera. Lepidoptera and/or herbicide resistance (cultivars HC33CRW×LH287BTCRW, LH332RR×LH324BT, LH24-4RR×LH324 and FR 1064LL×FR 2108) are treated in 2 replications against the armyworm (Spodoptera frugiperda). Application is carried out by drench application with the respective active compound at the desired application rate.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed.
Here, a markedly improved control of the pests compared to the control plants not treated according to the invention can be seen.













Concentration
Kill rate


Active compound
in ppm
in % after 6d

















I-4
100
15


I-10
100
0


I-6
100
0


VSN-BTCRW

45


Cry1Ab&Cry3Bb1


VSN-RR BT

60


Cry1Ab&Cp4epsps


VSN-RR

0


Cp4epsps


FR1064LL × FR 2108

0


herbicide resistance












found*
calc.**


I-4 + VSN-BTCRW
100
70
53.25


according to the invention


I-10 + VSN-RR BT
100
80
60


According to the invention


I-10 + VSN-RR
100
20
0


according to the invention


I-6 + FR1064LL × FR 2108
100
45
0


according to the invention





*found = activity found


**calc. = activity calculated using Colby's formula

## Claims

1. A method of improving the production potential of a transgenic plant, which comprises at least one gene or gene fragment coding for a Bt toxin or is herbicide tolerant, comprising treating said plant with an effective amount of at least one compound of formula (I)



in which
A represents 6-fluoropyrid-3-yl, 6-chloropyrid-3-yl, 6-bromopyrid-3-yl, 5-fluoro-6-chloropyrid-3-yl, 2-chloro-1,3-thiazol-5-yl or 5,6-dichloropyrid-3-yl and
R1 represents methyl, cyclopropyl, methoxy, 2-fluoroethyl or 2,2-difluoroethyl.

2. The method according to claim 1, wherein the compound of formula (I) is selected from the group consisting of compounds of the formulae (I-4), 4-{[(6-chloropyrid-3-yl)methyl](2-fluoroethyl)amino}furan-2(5H)-one,



(I-5), 4-{[(6-chloropyrid-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one,




(I-6), 4-{[(6-chloro-5-fluoropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one,




and (I-10), 4-{[(6-chloropyrid-3-yl)methyl](methyl)amino}furan-2(5H)-one,

3. The method according to claim 1, wherein the transgenic plant is a vegetable plant, maize plant, soya bean plant, cotton plant, tobacco plant, rice plant, sugar beet plant, oilseed rape plant or potato plant.

4. The method according to claim 1, wherein the compound of the formula (I) is present in a mixture with at least one mixing partner.

5. The method according to claim 4, wherein the mixing partner is an insecticide, an attractant, a sterilant, an acaricide, a nematicide, a fungicide, a growth-regulating substance, or a herbicide.

6. The method according to claim 1, wherein
A represents 6-chloropyrid-3-yl or 5-fluoro-6-chloropyrid-3-yl and
R1 represents methyl, 2-fluoroethyl or 2,2-difluoroethyl.

7. The method according to claim 1, wherein the compound of formula (I) is present in an oil-based suspension concentrate further comprising at least one vegetable oil or mineral oil, at least one nonionic surfactant and/or at least one anionic surfactant, and optionally, one or more additives selected from the group consisting of emulsifiers, foam inhibitors, preservatives, antioxidants, colorants and/or inert filler materials.

8. The method according to claim 1, wherein the compound of formula (I) is present in a composition further comprising at least one ammonium or phosphonium salt, and optionally, penetrants.

9. The method according to claim 1, wherein the compound of the formula (I) is applied at an application rate of from 0.1 g/h to 5.0 kg/ha.

10. The method according to claim 1, wherein the compound of the formula (I) is applied at an application rate of from 0.1 g/h to 500 g/ha.

11. The method according to claim 1, wherein the compound of the formula (I) is applied at an application rate of from 50 g/h to 500 kg/ha.

12. The method according to claim 1, wherein the transgenic plant is a Bt plant.

13. The method according to claim 1, wherein the transgenic plant is a herbicide tolerant plant.

14. The method according to claim 1, wherein the transgenic plant is a herbicide tolerant plant and a Bt plant.

15. The method according to claim 1, wherein the transgenic plant is a cotton plant or a maize plant.