U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Poultry Production and Product Safety Research: Fayetteville, AR
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    CareersSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Southeast Area Fayetteville, Arkansas Poultry Production and Product Safety Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications
- IACUC Executive Summary 8.29.17
- IACUC Executive Summary 1.15.18
- IACUC Excecutive Summary 7.16.18
- IACUC Executive Summary 2.4.19
- IACUC Executive Summary 7.31.19
- IACUC Executive Summary 1.31.20
- IACUC Executive Summary 7.31.20
- IACUC Excecutive Summary 1.29.21
- IACUC Executive Summary 7.30.21
- IACUC Executive Summary 1.28.22
- IACUC Executive Summary 7.29.22
- IACUC Executive Summary 1.30.23
- IACUC Executive Summary 7.28.23

Title:   Author  item
                                            NAVA, G - UNIVERSITY OF ARKANSASitem
                                            HIGGINS, STACY - UNIVERSITY OF ARKANSASitem
                                            BIELKE, LISA - UNIVERSITY OF ARKANSASitem
                                            TELLEZ, GUILLERMO - UNIVERSITY OF ARKANSASitem
                                            Nisbet, Daviditem
                                            Anderson, Robinitem
                                            Donoghue, Ann

                                                         - *Annie*item
                                            HARGIS, BILLY - UNIVERSITY OF ARKANSAS
  Submitted to: Biofilms
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 8/22/2003
                                    Publication  Date: 11/1/2003
                                    Citation: Nava, G., Higgins, S., Bielke, L., Tellez, G., Nisbet, D.J., Anderson, R.C., Donoghue, A.M., Hargis, B. 2003. Biofilm development as an important factor in the virulence of intestinal bacteria. [abstract]. Biofilms. p. 144.Interpretive Summary:
                                Technical Abstract: Microbial characteristics associated with virulent bacteria include type I pili (TIP), curli production (CP), motility (M), hemolytic reaction (HR), and resistance to the lytic action of host complement (RHC). The role of biofilm production (BP) has not been considered as an important factor of virulence for promoting bacterial colonization of epithelial surfaces, entry into host cells, and exchange of genetic material between bacteria, and competition for intestinal niches. The aim of the present study was to estimate the relationship of selected virulence parameters and BP between pathogenic and endemic intestinal bacteria by comparing the occurrence of these factors. Eight avian pathogenic strains (E. coli O1:K1, E. coli O78:K8, E. coli-Brown, Salmonella enteritidis, Salmonella typhimurium, E. coli O2, E. coli O2:K1, E. coli O1) and seven endemic non-pathogenic intestinal strains (five E. coli isolates, Klebsiella trevisanii, and Kluyvera ascorbata) isolated from avian intestine were evaluated. Assays for TIP, CP, M, HR, CR, and BD were performed to each isolate. All pathogenic strains were positive to CP and RHC. Of these pathogenic strains, only Salmonella typhimurium and E. coli O2:K1 (intermediate RHC) failed to produce appreciable biofilm while the rest of the pathogenic strains were positive in the BP assay. Four of the endemic intestinal strains were positive to CP and produced appreciable amount of biofilm in the BP assay, additionally, three of these bacteria were RHC positive. A casual relationship was not observed between parameters described above and TIP, M, or HR assays in comparison between pathogenic or non-pathogenic bacteria. These results suggest that biofilm production could be an important factor in the virulence of pathogenic bacteria given that it could be used as a advantage to avoid immune, cellular, and chemical systems of host defense.  However, BP alone does not necessarily predict virulence as some pathogenic isolates failed to produce biofilm and some non-pathogenic isolates did produce appreciable amounts of biofilm.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov