U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Kapczynski, Darrellitem
                                            PHILBIN, VICTORIA - INST FOR ANML HLTH- UKitem
                                            SMITH, ADRIAN - INST FOR ANML HLTH-UKitem
                                            Holt, Peter
  Submitted to: American Association of Avian Pathologists
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 2/8/2005
                                    Publication  Date: 7/17/2005
                                    Citation: Kapczynski, D.R., Philbin, V.J., Smith, A.L., Holt, P.S. 2005. Functional characterization and phylogenetic comparison of the chicken toll-like receptor 7 [abstract]. American Association of Avian Pathologists. p.56.Interpretive Summary:
                                Technical Abstract: Abstract: Toll-like receptor (TLR) family members are responsible for recognizing the presence of invading microorganisms through pathogen-associated molecular patterns and initiation of immune responses.  Recently, several chicken TLR's have been identified, including TLR7, which is reported to be involved with recognition of ribonucleic acid components characteristic of viral genomes (e.g. ssRNA).  In this study, we compared the innate immune response of the avian macrophage cell line, HD11 (TLR7+), to the synthetic TLR7 agonist Loxoribine and live or killed Newcastle disease virus.  In addition, the phylogenetic relationship of various TLR7's from avian and mammalian origin will be discussed.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov