U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Salfen, Brentitem
                                            Carroll, Jeffery

                                                         - *Jeff Carroll*item
                                            KEISLER, DUANE - UNIV OF MISSOURI
  Submitted to: Journal of Endocrinology
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 5/23/2003
                                    Publication  Date: 6/4/2003
                                    Citation: SALFEN, B.E., CARROLL, J.A., KEISLER, D.H. ENDOCRINE RESPONSES TO SHORT-TERM FEED DEPRIVATION IN WEANLING PIGS. JOURNAL OF ENDOCRINOLOGY. 2003. V. 178. P. 541-551.Interpretive Summary: Low feed intake by pigs during weaning leads to a suppression of weight gain and may also increase susceptibility to diseases.  Our objective was to characterize the hormonal changes that take place during a feed-deprivation period similar to that commonly observed during weaning in pigs.  The study elucidated the endocrine control of feed intake in pigs and may prove useful in developing methods to increase feed intake in pigs during weaning, when feed intake is typically low.  If a method of increasing feed intake in pigs can be developed, the health and growth of the pig will be increased.  This will result in pigs that reach market weight faster, thus saving the producer money associated with feed, medication and facility costs.  The end result will be an increased efficiency of pork production.  This data will be of interest to all individuals associated with swine production including scientists in academia, government, and industry.
                                Technical Abstract: Low feed intake by pigs during weaning leads to a suppression of weight gain and may also increase susceptibility to diseases.  Our objective was to characterize the hormonal changes that take place during a feed-deprivation period similar to that commonly observed during weaning in pigs.  In Experiment 1, eight barrows were either fed on a continual basis (CON; n = 4) or were feed deprived for 24 h and then re-fed until 30 h (FD; n = 4).  Relative serum concentrations of ghrelin tended to be lower in FD pigs at 12 h (P = 0.08) when compared to CON pigs, but greater than CON pigs at 24 and 30 h (P < 0.01).  Serum IGF-I was lower in FD pigs from 12 to 30 h as compared to CON pigs (P < 0.05) and increased following re-feeding (P < 0.06).  Experiment 2 included of 32 pigs that were either fed (CON72 and CON96; n = 16), feed deprived for 72 h (FD72; n = 8), or FD72 and then re-fed from 72-96 h (FD72/RF24; n = 8).  Ghrelin in the FD72 and FD72/RF24 groups was lower at 12 h (P < 0.03), but greater at 36 h and 48 h than CON pigs (P < 0.01).  Serum IGF-I and leptin decreased following feed deprivation (P < 0.001) and remained low until re-feeding.  Cortisol was elevated from 12 h to 72 h during feed deprivation (P < 0.01), but was not different from CON96 pigs following re-feeding (P > 0.88).  Expression of ghrelin mRNA tended to be lower in the FD72 pigs¿ stomachs, pituitary glands, and hypothalami (P = 0.06, 0.07, and 0.08, respectively), compared to CON pigs.  These results provide evidence that feed deprivation is accompanied by multiple changes in the endocrine and neuroendocrine axis which influences feed intake, somatotrophic response, and HPA axis hormone concentrations.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov