U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            BAUTISTA, D - COLLEGE OF VET. MED.item
                                            ELANKUMARAN, E - COLLEGE OF VET. MED.item
                                            HECKERT, R - COLLEGE OF VET. MED.item
                                            BABU, U - FDAitem
                                            SHEELA, R - UNIVERSITY OF MARYLANDitem
                                            SONG, W - UNIVERSITY OF MARYLANDitem
                                            OKAMURA, M - USDAitem
                                            RAYBOURNE, R - FDAitem
                                            Lillehoj, Hyun
  Submitted to: North Central Avian Disease Conference
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 2/4/2001
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Vaccination strategies for the prevention and eradication of Salmonella require further insight into the immunological mechanisms of infection, resistance to infection and elimination of Salmonella.  We have attempted to examine the relative roles of some components of the local and systemic immune system after vaccination and infection with Salmonella.  Four groups sof SOF leghorns were reared in separate isolation units for 4 weeks.  The first group (n=8) was vaccinated with a live, avirulent vaccine strain at 1 day of age and received a booster dose at 14 days; the second (n=8), with an inactivated bacterin against various Salmonella species at the same time and interval as the first group; the third (n=8) was experimentally infected with a wild type Salmonella enteritidis (SE) PT4 at 1 day of age; the fourth (n=8) served as a control.  Eight birds from each group were sacrificed and bled at 4 weeks of age.  IgA, IgG, and IgM responses to  Salmonella in serum and IgA in intestinal mucus were determined by isotype specific ELISA.  Mean sample-to-positive (S/P) ratios of all three experimental groups were elvated at 4 weeks for all isotypes relative to the control.  The two vaccinated groups showed higher serum antibody responses relative to the SE-infected group and control.  Salmonella- specific IgA in the intestinal mucus at 4 weeks of age was detected in only 2/8 birds in the inactivated vaccine group.  Intestinal IgA from the other groups were negligible.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov