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ARS Home Southeast Area Stoneville, Mississippi Genomics and Bioinformatics Research Research





- Rivers, Adam
- Vaughn, Justin
- Plant Genetic Resources, Genomics and Genetic Improvement (301)

Research Project: **Location:
                            Genomics and Bioinformatics Research** Project Number: 6066-21310-006-029-A
                        
                        Project Type: Cooperative Agreement Start Date: Apr 1, 2024
                        
                        End Date: Aug 31, 2024 **Objective:**
                        
                        Evaluate Salmonella pathogenicity using a gentamicin protection assay. The Cooperator will collect preliminary data for the development of a single-cell DNAseq based version of the gentamicin protection assay. **Approach:**
                        
                        Approximately 100 publicly available Salmonella isolates will be evaluated for the ability to invade or proliferate in one or more mammalian cell lines. The screen will be done using the gentamicin protection assay. Preliminary experiments of single cell RNAseq will also be designed.


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