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Title:   Author  item
                                            TURNER, STACY - IOWA STATE UNIVERSITYitem
                                            Wise, Roger
  Submitted to: Plant and Animal Genome Conference Proceedings
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 1/15/2003
                                    Publication  Date: 1/15/2003
                                    Citation: Turner, S., Wise, R.P. 2003. Evolutionary organization of the Mla locus in the poaceae. Plant and Animal Genome Conference Proceedings. XI Conference. p. 351.Interpretive Summary:
                                Technical Abstract: The Mla locus in barley contains 30 possible genes over a 260-kb region of chromosome 5 (1H), one of the highest gene densities in the Triticeae. Within the cereals, much of the model rice genome is syntenic to the larger, more complex species. However, genes encoding resistance to pathogens frequently evade synteny, possibly due to selection pressure resulting in their reorganization. To examine the evolution of the gene-dense Mla region in the Poaceae, we compared each of the putative coding regions of the 260-kb Mla complex to the sequenced rice genome in GenBank, Gramene, and TIGR. Although a few clusters of genes within the 260-kb Mla locus map to rice chromosomes 1, 5, and 10, most of the coding regions have significant similarity across several different rice chromosomes. These results indicate that much of the organization of the Mla locus in barley occurred after its divergence from rice.


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