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Title:   Author  item
                                            Straus, David

                                                         - *Dave*item
                                            Griffin, Billy
  Submitted to: Investigational New Animal Drugs Meeting - Book of Abstracts
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 7/9/2001
                                    Publication  Date: 8/3/2001
                                    Citation: STRAUS, D.L., GRIFFIN, B.R. EFFICACY OF POTASSIUM PERMANGANATE AS A THERAPEUTANT TO TREAT ICHTHYOPHTHIRIASIS IN CHANNEL CATFISH.. INVESTIGATIONAL NEW ANIMAL DRUGS MEETING - BOOK OF ABSTRACTS. 2001.Interpretive Summary:
                                Technical Abstract:   Ichthyophthiriasis can be controlled with KMnO4, but reports of its effectiveness have not been completely confirmed.  These studies were set u to determine the acute toxicity of KMnO4 to I. multifiliis theronts and the econcentrations needed to prevent an initial or stop an active infestation I. multifiliis in juvenile channel catfish Ictalurus punctatus.  Free-swimm theronts were exposed to concentrations of KMnO4 in well water in 96-well plates and observed for 4 h to determine the acute toxicity.  The 4 h-LC50 value was estimated to be 0.77 mg/L.  Channel catfish were exposed to 10,00 theronts/L of well water and immediately treated with a single dose of KMnO to determine the concentration needed to prevent the establishment of ichthyophthiriasis.  The lowest effective dose of KMnO4 was 1.0 mg/L.  In  another study designed to determine the concentration needed to stop an ac epizootic, fish were infested with I. multifiliis and allowed to develop immature trophonts.  They were then moved to individual static containers w 2 L of filtered well water and were treated with KMnO4 daily for 10 days; water was exchanged daily prior to treatment.  The lowest effective dose (d required to eliminate trophonts) of KMnO4 was 1.25 mg/L.  These results indicate that low concentrations of KMnO4 are effective for controlling I. multifiliis in clean water.  Effective treatment of pond water will be strongly influenced by the concentration of easily oxidizable substances in the water.


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