117TH CONGRESS 

2D SESSION S. 4120 

AN ACT 

To maximize discovery, and accelerate development and availability, of promising childhood cancer treatments, and 

for other purposes. 

1 Be it enacted by the Senate and House of Representa2 tives of the United States of America in Congress assembled, 
2 

†S 4120 ES

1 SECTION 1. SHORT TITLE. 

2 This Act may be cited as the ‘‘Childhood Cancer Sur3 vivorship, Treatment, Access, and Research Reauthoriza4 tion Act of 2022’’ or the ‘‘Childhood Cancer STAR Reau5 thorization Act’’. 

6 SEC. 2. REAUTHORIZING AND IMPROVING THE CHILDHOOD 

7 STAR ACT. 

8 (a) CHILDREN’S CANCER BIOREPOSITORIES.—Sec9 tion 417E of the Public Health Service Act (42 U.S.C. 

10 285a–11) is amended— 

11 (1) in subsection (a)— 

12 (A) in paragraph (2)(A), by inserting be13 fore the period at the end of the second sen14 tence the following: ‘‘, such as collected samples 

15 of both solid tumor cancer and paired samples’’; 

16 (B) in paragraph (9), by striking ‘‘Child17 hood Cancer Survivorship, Treatment, Access, 

18 and Research Act of 2018’’ and inserting 

19 ‘‘Childhood Cancer Survivorship, Treatment, 

20 Access, and Research Reauthorization Act of 

21 2022’’; 

22 (C) by redesignating paragraph (10) as 

23 paragraph (11); and 

24 (D) by inserting after paragraph (9) the 

25 following: 
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†S 4120 ES

1 ‘‘(10) REPORT ON RESEARCHER ACCESS TO

2 CHILDREN’S CANCER BIOREPOSITORY SAMPLES.— 

3 Not later than 2 years after the date of enactment 

4 of the Childhood Cancer Survivorship, Treatment, 

5 Access, and Research Reauthorization Act of 2022, 

6 the Director of NIH shall— 

7 ‘‘(A) conduct a review of the procedures 

8 established under paragraph (2)(C) and other 

9 policies or procedures related to researcher ac10 cess to such biospecimens to identify any oppor11 tunities to reduce administrative burden, con12 sistent with paragraph (2)(D), in a manner 

13 that protects personal privacy to the extent re14 quired by applicable Federal and State privacy 

15 law, at a minimum; and 

16 ‘‘(B) submit to the Committee on Health, 

17 Education, Labor, and Pensions of the Senate 

18 and the Committee on Energy and Commerce 

19 of the House of Representatives a report on the 

20 findings of the review under subparagraph (A) 

21 and whether the Director of NIH plans to make 

22 any changes to the policies or procedures con23 sidered in such review, based on such find24 ings.’’; and 
4 

†S 4120 ES

1 (2) in subsection (d), by striking ‘‘2019 through 

2 2023’’ and inserting ‘‘2024 through 2028’’. 

3 (b) CANCER SURVIVORSHIP PROGRAMS.—Section 

4 201 of the Childhood Cancer Survivorship, Treatment, Ac5 cess, and Research Act of 2018 (Public Law 115–180) 

6 is amended— 

7 (1) in subsection (a)— 

8 (A) in the subsection heading, by striking 

9 ‘‘PILOT PROGRAMS TO EXPLORE’’ and inserting 

10 ‘‘RESEARCH TO EVALUATE’’ 

11 (B) in paragraph (1)— 

12 (i) by striking ‘‘may make awards to 

13 eligible entities to establish pilot pro14 grams’’ and inserting ‘‘shall, as appro15 priate, make awards to eligible entities to 

16 conduct or support research’’; 

17 (ii) by striking ‘‘model systems’’ and 

18 inserting ‘‘approaches’’; 

19 (iii) by inserting ‘‘and adolescent’’ 

20 after ‘‘childhood’’; and 

21 (iv) by striking ‘‘evaluation of models 

22 for’’; 

23 (C) in paragraph (2)— 

24 (i) in subparagraph (A), in the matter 

25 preceding clause (i), by inserting ‘‘within 
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1 the existing peer review process,’’ after 

2 ‘‘practicable,’’; and 

3 (ii) in subparagraph (B)(v), by strik4 ing ‘‘in treating survivors of childhood can5 cers’’ and inserting ‘‘in carrying out the 

6 activities described in paragraph (1)’’; and 

7 (D) in paragraph (3)(B)(v), by striking 

8 ‘‘design of systems for the effective transfer of 

9 treatment information and care summaries 

10 from cancer care providers to other health care 

11 providers’’ and inserting ‘‘design tools to sup12 port the secure electronic transfer of treatment 

13 information and care summaries between health 

14 care providers or, as applicable and appropriate, 

15 longitudinal childhood cancer survivorship co16 horts’’; and 

17 (2) in subsection (b)— 

18 (A) in each of paragraphs (1) and (2), by 

19 striking ‘‘date of enactment of this Act’’ and in20 serting ‘‘date of enactment of the Childhood 

21 Cancer Survivorship, Treatment, Access, and 

22 Research Reauthorization Act of 2022’’; and 

23 (B) in paragraph (1)— 

24 (i) by striking subparagraphs (A) and 

25 (C); 
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†S 4120 ES

1 (ii) by redesignating subparagraph 

2 (B) as subparagraph (A); and 

3 (iii) by adding at the end the fol4 lowing: 

5 ‘‘(B) recommendations for enhancing or 

6 promoting activities of the Department of 

7 Health and Human Services related to work8 force development for health care providers who 

9 provide psychosocial care to pediatric cancer pa10 tients and survivors.’’. 

Passed the Senate December 20, 2022. 

Attest: 

Secretary. 

117TH CONGRESS 

2D SESSION S. 4120 

AN ACT 

To maximize discovery, and accelerate development 

treatments, and for other purposes. and availability, of promising childhood cancer