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ARS Home Midwest Area Ames, Iowa National Animal Disease Center Infectious Bacterial Diseases Research Research Publications at this Location





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Title:   Author  item
                                            Whipple, Dianaitem
                                            Waters, Wadeitem
                                            Palmer, Mitchell
  Submitted to: Meeting Abstract
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 9/18/2003
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: White-tailed deer in northeast Michigan are recognized as a wildlife reservoir host species of Mycobacterium bovis.  Since 1998, tuberculosis has been diagnosed in 29 herds of cattle in northeast Michigan. Results of DNA fingerprinting indicate that the cattle are infected with the same strain of M. bovis as the deer.  The purpose of this study was to determine if cattle can become infected with M. bovis through indirect contact with experimentally infected deer and contaminated feed.  The study was divided into three phases and a different group of calves and deer were used for each phase.  In phase 1, deer were experimentally infected with M. bovis and after two weeks, calves were introduced into the barn.  Deer were offered excess feed each day.  In the mornings, calves were moved to the soiled deer pens and given access to the feed.  Deer were moved to clean pens and again offered excess feed.  In phase 2, groups of calves were given feed spiked with a high and low dosage of M. bovis.  In phase 3, deer were experimentally infected with M. bovis as in phase 1; however, the feed was moved between pens of deer and calves rather than moving the animals.  In all three phases, calves became infected with M. bovis and had lesions suggestive of an inhalation route of exposure.


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