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Title:   Author  item
                                            Anderson, Robinitem
                                            CARR, M - ANGELO STATE UNIVitem
                                            Jung, Yong Sooitem
                                            Genovese, Kenneth

                                                         - *Ken*item
                                            Callaway, Todditem
                                            Edrington, Thomasitem
                                            Elder, Robertitem
                                            Beier, Rossitem
                                            Hume, Michaelitem
                                            Nisbet, David
  Submitted to: International Symposium and Workshop on Shiga Toxin ... Escherichia coli
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 6/10/2003
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: An experiment was conducted to test the effecicacy of experimental preharvest feed or water supplements on reducing E. coli in cattle. Sixty-four finished heifers averaging 402 ± 5 (SE) kg body weight were sorted to one of eight treatments in a 2 X 4 factorial design (two drinking water treatments X four feed treatments) that was replicated four times thus achieving an n of eight animals/treatment. The water treatments (a 0X control treatment or a specially prepared 1X solution containing <2500 ppm active chlorate) were provided free choice during the last 12 hours prior to being shipped to slaughter. The feed treatments contained supplements (% of body weight) of an experimental chlorate product (EKA Chemicals Inc., Marietta, GA) at 0%, 0.01% for last day on feed, 0.01% for last 5 days on feed or 0.05% for last day on feed. An effect (P<0.05; SEM=0.40) of drinking water treatment was observed on recovery of ruminal but not fecal E. coli, with ruminal concentrations from animals provided the 1X solution alone (2.98 log10 cfu/g) being nearly 10-fold lower than from controls (3.95 log10 cfu/g). An effect (P<0.05; SEM=0.51) of feed treatment was observed on fecal but not ruminal E. coli concentrations, with fecal concentrations being reduced by as much as 200-fold from those observed in control animals (5.64 log10 cfu/g). Feed treatment reduced (P<0.05; SEM=0.16) recovery of E. coli from swabs taken from the left rump area with control concentrations (5.36 log10 cfu/swab) being 10-fold or higher than swabs collected from any of the other treatments. No adverse effects were observed on animal health or performance thus demonstrating that the preparations were safe for the animals.


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