U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Food and Feed Safety Research: College Station, TX
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    CareersSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Plains Area College Station, Texas Southern Plains Agricultural Research Center Food and Feed Safety Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Beier, Rossitem
                                            WHITE, DAVID - FDAitem
                                            MCDERMOTT, PATRICK - FDAitem
                                            FOLEY, STEVEN - UNIV OF CENTRAL ARitem
                                            ZHAO, SHAOHUA - FDAitem
                                            Hume, Michaelitem
                                            Poole, Toniitem
                                            Nisbet, Daviditem
                                            WALKER, R - FDA
  Submitted to: National Foundation for Infectious Disease
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 5/7/2004
                                    Publication  Date: 6/28/2004
                                    Citation: Beier, R.C., White, D.G., McDermott, P.F., Foley, S.L., Zhao, S., Hume, M.E., Poole, T.L., Nisbet, D.J., Walker, R.D. 2004. Characterization of antimicrobial resistance among Pseudomonas aeruginosa isolates recovered from companion animals, 1994-2003 [abstract]. 2004 Conference on Antimicrobial Resistance. p. 40.Interpretive Summary:
                                Technical Abstract: Background: Several fluoroquinolones are currently approved in the United States for treatment of skin and associated soft tissue infection. However, increasing reports of resistance among P. aeruginosa isolates associated with canine otitis may affect the choice of antimicrobials for systemic administration in companion animals. Here we evaluated the susceptibility of P. aeruginosa isolates recovered from companion animals across the U.S. from 1994-2003 to determine shifts in susceptibility among veterinary and human use antimicrobials, including several fluoroquinolones.  
Methods: One hundred seventy-seven P. aeruginosa isolates collected primarily from dogs (n = 155) and eight other animals from sixteen states during 1994-2003 were tested for susceptibility to antimicrobials of human and veterinary importance using NCCLS broth microdilution methods.  
Results: The majority of P. aeruginosa isolates (75-100%) were resistant to most of the antimicrobials tested, including chloramphenicol (99%), tetracycline (98%), kanamycin (80%), sulfamethoxazole (77%), ceftriaxone (69%). Resistance was also observed to gentamicin (9%) and several fluoroquinolones including enrofloxacin (45%), orbifloxacin (44%), difloxacin (38%), ciprofloxacin (5%). There did not appear to be an overall increasing rate of resistance to fluoroquinolones among P. aeruginosa isolates with the exception of two time periods, 1994-1996, and 2000.
Conclusions: Observed rates of resistance to several antimicrobials merit sustained surveillance of companion animal isolates to detect emerging antimicrobial resistance phenotypes and empirical treatment of P. aeruginosa infections may be problematic.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov