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Title:   Author  item
                                            Jung, Yong Sooitem
                                            Anderson, Robinitem
                                            Genovese, Kenneth

                                                         - *Ken*item
                                            Edrington, Thomasitem
                                            Callaway, Todditem
                                            Byrd Ii, James

                                                         - *Allen*item
                                            Bischoff, Kennethitem
                                            Harvey, Rogeritem
                                            MCREYNOLDS, JACK - TX A&M UNIVERSITYitem
                                            Nisbet, David
  Submitted to: International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork
                                    Publication Type: Proceedings
                                    Publication Acceptance Date: 9/9/2003
                                    Publication  Date: 10/1/2003
                                    Citation: Jung, Y., Anderson, R.C., Genovese, K.J., Edrington, T.S., Callaway, T.R., Byrd II, J.A., Bischoff, K.M., Harvey, R.B., McReynolds, J., Nisbet, D.J. 2003. Reduction of Campylobacter and Salmonella in pigs treated with a select nitrocompound. Proceedings of 5th International Symposium on the Epidemiology and Control of Foodborne Pathogens in Pork (SafePork '03). p. 205-207.Interpretive Summary:
                                Technical Abstract: The aim of this study was to test the effectiveness of administering a select nitrocompound (S-NO) on reducing naturally colonized Campylobacter and experimentally infected Salmonella in the weaned pig gut.  Pigs were divided into four groups; control (0 g S-NO/pig), 1X (0.2 g S-NO/pig), 5X (1 g S-NO/pig), and 10X (2 g S-NO/pig).  Treatments were administered via oral gavage 24 h before sacrifice.  Mean +/- SD populations (log10 cfu/g) of Campylobacter in the cecum were reduced (P < 0.05) in pigs receiving the 10 X dose when compared with untreated controls (1.64 +/- 1.30 vs 5.31 +/- 0.58, respectively).  Campylobacter concentrations in rectal contents from pigs administered the 5X dose were reduced (P < 0.05) compared to control (2.65 +/- 2.86 vs 5.90 +/- 0.94, respectively).  Rectal Salmonella concentrations were reduced (P < 0.05) in all of the S-NO-treated groups.  No adverse effects of S-NO on pig health were observed.  These results demonstrate that S-NO may have potential as a preharvest intervention strategy that can reduce colonization by Campylobacter and Salmonella in pigs.


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