U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Northeast Area Beltsville, Maryland (BHNRC) Beltsville Human Nutrition Research Center Food Components and Health Laboratory Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Novotny, Janetitem
                                            GREIF, PETER - NIHitem
                                            BOSTON, RAYMOND - UNIVERSITY OF PENNA
  Submitted to: Advances in Experimental Medicine and Biology
                                    Publication Type: Peer Reviewed Journal
                                    Publication Acceptance Date: 1/10/2003
                                    Publication  Date: 1/10/2003
                                    Citation: Novotny Dura, J., Greif, P., Boston, R.C. 2003. Winsaam: Software for simulation, analyis, and modeling. Advances in Experimental Medicine and Biology. 537:343-356Interpretive Summary: Understanding metabolism of nutrients and other compounds by the human body requires complicated computer software packages. This is because the human body is so complex that mathematics is often required to understand the research data. One such package is called WinSAAM. The WinSAAM modeling software is the newest version of the SAAM software series, which  was initiated in the 1950's and has been continually enhanced to meet expanding needs of modeling research. WinSAAM combines the complex mathematical core of the original program (SAAM) with new state-of-the-art tools. These tools include a Windows environment, a text editor, a spreadsheet for manipulating data, and a graphics package for making formatted plots of results. The WinSAAM package also includes a complicated statistical routine to calculate metabolism rates for a large population of individuals from a smaller number of study subjects. This  and the many other features of the WinSAAM software package make it a powerful tool for analysis of kinetic data from metabolism studies. This report will be used by scientists performing mathematical modeling for analysis of metabolism data.
                                Technical Abstract: The WinSAAM modeling software is the newest version of the SAAM software series, which was initiated in the 1950's and has been continually enhanced to meet expanding needs of modeling research.  WinSAAM is an integrated package of mathematical, simulation, and graphical tools for analysis of biokinetic data. Among WinSAAM's capabilities are two basic  functions for modeling: solving equations (which describe a model) and performing least squares fitting of model solutions to data for parameter estimation. This newest version of SAAM allows these functions to be executed through an easy-to-use graphical interface, which utilizes pull- down menus for common commands, multiple windows for model assessment and modification, spreadsheet tools for data manipulation, and a graphics package for display of results. One of the most sophisticated new functions of WinSAAM is the Project Management tool. This tool allows the  modeler to investigate the distribution of parameter values associated with a population of individuals. Data pooling to calculate simple means and standard deviations does not provide an accurate description of the population parameters. The WinSAAM program takes into account the covariance of parameters and uses maximum likelihood criteria to converge to a final solution of population parameter values. This is a crucial mathematical tool for accurately describing rates of metabolism from modeling studies.  This and the may other features of the WinSAAM software package make it a powerful tool for the analysis of biokinetic data.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov