U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Infectious Bacterial Diseases Research: Ames, IA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    CareersSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Midwest Area Ames, Iowa National Animal Disease Center Infectious Bacterial Diseases Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Palmer, Mitchellitem
                                            Whipple, Diana
  Submitted to: American Association of Veterinary Laboratory Diagnosticians
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 10/21/2000
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Surveys of free-ranging deer in Michigan have identified the first known epidemic of tuberculosis in white-tailed deer.  Information is lacking on the transmissibility of Mycobacterium bovis among deer.  To determine the efficiency and routes of transmission between deer we exposed non- inoculated deer to deer that had been experimentally inoculated by  intratonsilar instillation of 2x10**5 CFU of M. Bovis.  Two in-contact dee were penned with two experimentally inoculated deer; each pen having a single source of water, hay, and pelleted feed.  Sixty-nine days after introduction, all in-contact deer manifested delayed type hypersensitivity (DTH) reactions to M. bovis purified protein derivative (PPD).  All experimentally inoculated deer were removed one hundred twenty days after inoculation.  One-hundred-fifty-nine days after introduction, four new non- lated deer were housed with the remaining original in-contact deer  such that two new in-contact deer were penned with two original in-contact deer.  One hundred days after introduction, all new in-contact deer demonstrated DTH to M. bovis PPD.  At 180 days after introduction of new in-contact deer, deer were euthanized and examined.  All in-contact exposed deer developed tuberculosis.  Lesions were most common in the lung and pulmonary lymph nodes.  Experimentally inoculated deer shed M. bovis in nasal secretions, saliva, feces, and urine.  In-contact infected deer also shed M. bovis in nasal secretions and saliva.  Hay and pelleted feed contained M. bovis at multiple times during the experiment.  Tuberculosis deer efficiently transmit M. bovis to other deer in close contact.  Lesion distribution suggests aerosol transmission, however, contamination of shared feed also must be considered.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov