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Title:   Author  item
                                            Moore, Randleitem
                                            Byrd Ii, James

                                                         - *Allen*item
                                            KNAPE, KOYLE - TEXAS A&M UNIVERSITYitem
                                            Anderson, Robinitem
                                            Callaway, Todditem
                                            Edrington, Thomasitem
                                            Kubena, Leonitem
                                            Nisbet, David
  Submitted to: Poultry Science
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 1/15/2002
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Previously, chlorate compounds have been observed to reduce E. coli and Salmonella infections in swine and broilers. The current studies were performed to investigate the effects of an experimental chlorate compound (C1) on Salmonella typhimurium (ST) infections of turkeys. Two experiments were performed to investigate the effect of concentration and duration of  C1 on crop and ceca Salmonella recovery. In all experiments, 15-week-old turkey toms were challenged with not less than 6.5*10**6 cfu of ST at 1 and 7 days prior to organ sampling, and following C1 treatment, subjected to a 10 h water withdrawal and an 8 h feed withdrawal prior to sampling. In Experiment 1, birds were administered either 0X, 1X, 2X, 3X, or 4X of the C1 (1X C1 is equivalent to a 7.5 mM chlorate ion concentration) in the drinking water for 38 h prior to withdrawal. For all treatment concentrations, turkeys provided C1 had significantly (P<0.05) lower  populations and incidences of crop (> 1.5 log reduction) and ceca (> 0.6 log reduction) ST as compared to controls. In Experiment 2, birds were administered a 3X concentration of C1 in the drinking water for either 0, 14, 26, or 38 h prior to withdrawal. For all treatment durations, turkeys provided with C1 had significantly lower populations and incidences of crop (> 2.2 log reduction) and ceca (> 1.5 log reduction) ST as compared to controls. These experiments suggest that the C1 significantly reduces Salmonella colonization in commercial turkeys when administered prior to feed and water withdrawal.


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