U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 Corn Insects and Crop Genetics Research: Ames, IA
 close



    Research

                    Research Projects
                                    Publications
                                    Collaborations
                                    News
                People

                    Staff Listing
                                    Careers


        


                    Database Projects
                        MaizeGDB
                                    SoyBase
                                    PeanutBase
                                    Legume Information System
                                    Maize Newsletter
                                    Maize Mutant Phenotypes
                                    Maize Genetics Conference
                                    Shiny Soybase CNV
                                    Shiny Soybase SNP
                                    Common Bean and Alfalfa - PvGEA
                                    Common Bean and Alfalfa - AGEDSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Midwest Area Ames, Iowa Corn Insects and Crop Genetics Research Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Wise, Rogeritem
                                            WEI, FUSHENG - IOWA STATE UNIVERSITYitem
                                            WING, ROD - CLEMSON UNIVERSITY
  Submitted to: Proceedings International Barley Genetics Symposium
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 10/15/2000
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Obligate fungal pathogens, such as rusts and mildews, are perhaps the greatest deterrent to cereal production worldwide.  Powdery mildew of grasses (barley, wheat, rye, and oats) is caused by the obligate fungal pathogen, Blumeria (=Erysiphe) graminis.  It is most damaging to barley in cool, wet climates, and can reduce yields up to 25%.  The primary means of  disease control is by incorporation of genetic resistance into elite varieties.  To discern the fundamental signaling mechanisms between the host plant cell and fungal pathogen, we have chosen the Mla resistance-gene cluster in barley as our model system.  Approximately 30 variants of the Mla locus have been identified in different cultivars, each giving a race- specific response to different isolates of B. graminis f. sp. hordei (reviewed by J rgensen 1994).  This extensive variability provides an ideal research tool to explore resistance-signaling mechanisms elicited by cereal lhosts to obligate fungal biotrophs, as well as the evolution of new resistance-gene specificities. In preparation for positional-cloning of the Mla locus, we saturated the Mla region with molecular markers and the Mla locus was delimited to a 240-kb physical interval bridged by two overlapping BAC (Bacterial Artificial Chromosome) clones.  As a first step to unravel the evolutionary mechanisms that gave rise to this interesting gene-rich region, we determined the complete DNA sequence of these Mla- spanning clones.  This is the first description of the complete DNA sequence of a complex resistance gene cluster from cereal crops.  The results described in this manuscript will impact scientists that work in the area of resistance gene signaling and molecular pathology as well as the field of plant pathology and molecular breeding.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov