|
|



UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549










FORM 20-F



(Mark One)



| ̈                                | Registration statement pursuant to Section
    12(b) or 12(g) of the Securities Exchange Act of 1934.                                                                                                           
|-------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|Or                               |                                                                                                                                                                                                                 
|x                                | Annual report pursuant to Section 13 or 15(d) of the
    Securities Exchange Act of 1934.For the fiscal year endedMay31, 2013.                                                                                  
|Or                               |                                                                                                                                                                                                                 
| ̈                                | Transition report pursuant to Section 13 or 15(d) of
    the Securities Exchange Act of 1934. For the transition period from ________ to ________ .                                                             
|Or                               |                                                                                                                                                                                                                 
| ̈                                | Shell
                                         company report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934.
        Date of event requiring this shell company report _______________.
|Commission file number 001-32001



LORUS THERAPEUTICS INC.

(Exact Name of Registrant as Specified
in Its Charter)



Canada

(Jurisdiction of Incorporation or Organization)



2 Meridian Road

Toronto, Ontario

M9W 4Z7

Canada

(Address of Principal Executive Offices)



Gregory Chow

Chief Financial Officer

2 Meridian Road

Toronto, Ontario M9W 4Z7

Canada

Telephone: (416) 798-1200

Facsimile: (416) 798-2200

(Name, Telephone, E-mail and/or Facsimile
number and Address of Company Contact Person)

Securities registered or to be registered pursuant to Section
12(b) of the Act: None



|Title
                                         of Each Class | Name of Each
    Exchange On Which Registered
|------------------------------------------------------------ | ---------------------------------------------
|                                                             |                                              

Securities registered or to be registered pursuant to Section 12(g) of the Act: Common Shares



Securities for which there is a reporting
obligation pursuant to Section 15(d) of the Act: None











Indicate the number of outstanding shares
of each of the issuer’s classes of capital or common stock as of the close of the period covered by the annual report.



Common Shares, without par value, at May
31, 2013: 42,251,081



Indicate by check mark if the registrant
is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act.



Yes  ̈
No x



If this is an annual or transition report,
indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Securities Exchange
Act of 1934.



Yes  ̈
No x



Indicate by check mark whether the registrant:
(1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding
12 months (or such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days.



Yes  ̈
No x



Indicate by check mark
whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File
required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding
12 months (or for such shorter period that the registrant was required to submit and post such files).



Yes  ̈No x



Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, or a non-accelerated filer. See definition of “accelerated filer and
large accelerated filer” in Rule 12b-2 of the Exchange Act.



Large accelerated filer  ̈Accelerated filer  ̈ Non-accelerated filer x



Indicate by check mark which basis of
accounting the registrant has used to prepare the financial statements included in this filing.



U.S. GAAP  ̈International Financial Reporting Standards as issued by the International Accounting Standards Board xOther  ̈



If “Other” has been checked
in response to the previous question, indicate by check mark which financial statement item the registrant has elected to follow.



Item 17  ̈Item 18  ̈



If this is an annual report, indicate
by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).



Yes  ̈No x











TABLE OF CONTENTS



|          |                                                                              | Page
|--------- | ---------------------------------------------------------------------------- | ----
|          |                                                                              |     
|PART I    |                                                                              | 2   
|          |                                                                              |     
|Item 1.   | Identity of Directors, Senior Management and Advisors                        | 2   
|Item 2.   | Offer Statistics and Expected Timetable                                      | 2   
|Item 3.   | Key Information                                                              | 2   
|Item 4.   | Information on the Company                                                   | 12  
|Item 4A.  | Unresolved Staff Comments                                                    | 27  
|Item 5.   | Operating and Financial Review and Prospects                                 | 27  
|Item 6.   | Directors, Senior Management and Employees                                   | 28  
|Item 7.   | Major Shareholders and Related Party Transactions                            | 43  
|Item 8.   | Financial Information                                                        | 46  
|Item 9.   | The Offer and Listing                                                        | 46  
|Item 10.  | Additional Information                                                       | 47  
|Item 11.  | Qualitative and Quantitative Disclosures about Market Risk                   | 56  
|Item 12.  | Description of Securities Other Than Equity Securities                       | 57  
|          |                                                                              |     
|PART II   |                                                                              | 58  
|          |                                                                              |     
|Item 13.  | Defaults, Dividends, Arrearages and Delinquencies                            | 58  
|Item 14.  | Material Modifications to the Rights of Security Holders and Use of Proceeds | 58  
|Item 15.  | Controls and Procedures                                                      | 58  
|Item 16.  | [Reserved]                                                                   | 59  
|Item 16A. | Audit Committee Financial Expert                                             | 59  
|Item 16B. | Code of Ethics                                                               | 59  
|Item 16C. | Principal Accountant Fees and Services                                       | 59  
|Item 16D. | Exemptions from the Listing Standards for Audit Committees                   | 60  
|Item 16E. | Purchases of Equity Securities by the Issuer and Affiliated Purchasers       | 60  
|          |                                                                              |     
|PART III  |                                                                              | 61  
|          |                                                                              |     
|Item 17.  | Financial Statements                                                         | 61  
|Item 18.  | Financial Statements                                                         | 61  
|Item 19.  | Exhibits                                                                     | 62  











GENERAL



On July 10, 2007
(the ”Arrangement Date”), Lorus Therapeutics Inc. completed a plan of arrangement and corporate reorganization
with, among others, 4325231 Canada Inc. (now Global Summit Real Estate Inc.), formerly Lorus Therapeutics Inc.
(“Old Lorus”), 6707157 Canada Inc. and Pinnacle International Lands, Inc. (the “Arrangement”).
As a result of the plan of arrangement and reorganization, among other things, each common share of Old Lorus was exchanged for
one Lorus Common Share and the assets (excluding certain deferred tax assets) and liabilities of Old Lorus (including all of the
shares of its subsidiaries) were transferred, directly or indirectly, to Lorus and/or our subsidiaries. We continued the business
of Old Lorus after the Arrangement Date with the same officers and employees and continued to be governed by the same directors
as Old Lorus prior to the Arrangement Date. In this Annual Report on Form 20-F, all references to “Lorus”,
the “Corporation”, the “Company”, “we”, “our”, “us”
and similar expressions, unless otherwise stated, are references to Old Lorus prior to the Arrangement Date and Lorus Therapeutics
Inc. (and where the context requires, Lorus Therapeutics Inc. and its subsidiary) after the Arrangement Date. References
to this “Form 20-F” and this “Annual Report” mean references to this Annual Report on Form
20-F for the fiscal year ended May 31, 2013.



We use the Canadian
dollar as our reporting currency. All references in this Annual Report to “dollars” or “$” are expressed
in Canadian dollars, unless otherwise indicated. See also “Item 3. Key Information” for more detailed currency and
conversion information. Our Consolidated Financial Statements, which form part of this Annual Report, are presented in Canadian
dollars and are prepared in accordance with International Financial Reporting Standards as issued by the International Accounting
Standards Board (“IFRS”), which differ in certain respects from accounting principles generally accepted in
the United States (“U.S. GAAP”).



FORWARD-LOOKING STATEMENTS



This Annual Report contains forward-looking
statements within the meaning of U.S. securities laws. Such statements include, but are not limited to, statements relating to:



| | · | our
                                         business strategy;
| | - | ---------------------------------------------------------------



| | · | our
                                         ability to obtain the substantial capital we require to fund research and operations;
| | - | ----------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         plans to secure strategic partnerships to assist in the further development of our product
                                         candidates;
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         plans to conduct clinical trials and pre-clinical programs;
| | - | --------------------------------------------------------------------------------------------------------



| | · | our
                                         expectations regarding the progress and the successful and timely completion of the various
                                         stages of our drug discovery, pre-clinical and clinical studies and the regulatory approval
                                         process;
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         plans, objectives, expectations and intentions; and
| | - | ------------------------------------------------------------------------------------------------



| | · | other
                                         statements including words such as “anticipate”, “contemplate”,
                                         “continue”, “believe”, “plan”, “estimate”,
                                         “expect”, “intend”, “will”, “should”,
                                         “may”, and other similar expressions.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Such statements reflect our current
views with respect to future events, are subject to risks and uncertainties, and are based upon a number of estimates and assumptions
that, while considered reasonable by us, are inherently subject to significant business, economic, competitive, political and
social uncertainties and contingencies. Many factors could cause our actual results, performance or achievements to be materially
different from any future results, performance, or achievements that may be expressed or implied by such forward-looking statements,
including, among others:



| | · | our
                                         ability to obtain the substantial capital we require to fund research and operations;
| | - | ----------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         lack of product revenues and history of operating losses;
| | - | ------------------------------------------------------------------------------------------------------



| | · | our
                                         early stage of development, particularly the inherent risks and uncertainties associated
                                         with (i) developing new drug candidates generally, (ii) demonstrating the safety and
                                         efficacy of these drug candidates in clinical studies in humans, and (iii) obtaining
                                         regulatory approval to commercialize these drug candidates;
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



1







| | · | our
                                         drug candidates require time-consuming and costly preclinical and clinical testing and
                                         regulatory approvals before commercialization;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | clinical
                                         studies and regulatory approvals of our drug candidates are subject to delays, and may
                                         not be completed or granted on expected timetables, if at all, and such delays may increase
                                         our costs and could delay our ability to generate revenue;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | the
                                         regulatory approval process;
| | - | -------------------------------------------------------------------------



| | · | our
                                         ability to recruit patients for clinical trials;
| | - | ---------------------------------------------------------------------------------------------



| | · | the
                                         progress of our clinical trials;
| | - | -----------------------------------------------------------------------------



| | · | our
                                         liability associated with the indemnification of Old Lorus and its directors, officers
                                         and employees in respect of a reorganization of the Company that occurred in 2007;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         ability to negotiate and enter into agreements with potential partners;
| | - | --------------------------------------------------------------------------------------------------------------------



| | · | our
                                         ability to attract and retain key personnel;
| | - | -----------------------------------------------------------------------------------------



| | · | our
                                         ability to obtain and maintain patent protection;
| | - | ----------------------------------------------------------------------------------------------



| | · | our
                                         ability to protect our intellectual property rights and not infringe on the intellectual
                                         property rights of others;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         ability to comply with applicable governmental regulations and standards;
| | - | ----------------------------------------------------------------------------------------------------------------------



| | · | development
                                         or commercialization of similar products by our competitors, many of which are more established
                                         and have or have access to greater financial resources than us;
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | commercialization
                                         limitations imposed by intellectual property rights owned or controlled by third parties;
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------



| | · | our
                                         business is subject to potential product liability and other claims;
| | - | -----------------------------------------------------------------------------------------------------------------



| | · | our
                                         ability to maintain adequate insurance at acceptable costs;
| | - | --------------------------------------------------------------------------------------------------------



| | · | further
                                         equity financing may substantially dilute the interests of our shareholders;
| | - | -----------------------------------------------------------------------------------------------------------------------------



| | · | changing
                                         market conditions; and
| | - | ------------------------------------------------------------------------



| | · | other
                                         risks detailed from time-to-time in our ongoing quarterly filings, annual information
                                         forms, annual reports and annual filings with Canadian securities regulators and the
                                         United States Securities and Exchange Commission (“SEC”), and those
                                         which are discussed under the heading “Risk Factors”.
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Should one or more
of these risks or uncertainties materialize, or should the assumptions set out in the section entitled “Risk Factors”
underlying those forward-looking statements prove incorrect, actual results may vary materially from those described herein. These
forward-looking statements are made as of the date of this Annual Report or, in the case of documents incorporated by reference
herein, as of the date of such documents, and we do not intend, and do not assume any obligation, to update these forward-looking
statements, except as required by law. Such statements may not prove to be accurate as actual results and future events could
differ materially from those anticipated in such statements. Investors are cautioned that forward-looking statements are not guarantees
of future performance and accordingly investors are cautioned not to put undue reliance on forward-looking statements due to the
inherent uncertainty therein. New factors emerge from time to time, and it is not possible for management of the Corporation to
predict all of these factors or to assess in advance the impact of each such factor on the Corporation’s business or the
extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any
forward-looking statement.



1









PART I



Item 1.          Identity
of Directors, Senior Management and Advisers



Not applicable.



Item 2.          Offer
Statistics and Expected Timetable



Not applicable.



Item 3.          Key
Information



A.           Selected
financial data.



The following tables
present our selected consolidated financial data. You should read these tables in conjunction with our audited Consolidated Financial
Statements and accompanying notes included inItem 18of this Annual Report and the “Management’s Discussion
and Analysis of Financial Condition and Results of Operations” included in Item 5 of this Annual Report.



The selected consolidated
financial information set forth below for each of the two years ended May 31, 2013 and 2012, has been derived from the Company's
audited consolidated financial statements as at and for the financial years ended May 31, 2013 and 2012 filed as part of this
Form 20-F under Item 18. These consolidated financial statements have been prepared in accordance with IFRS, which differ in certain
respects from the principles the Company would have followed had its consolidated financial statements been prepared in accordance
with U.S. GAAP. The selected consolidated financial information should be read in conjunction with the discussion in Item 5 of
this Form 20-F and the consolidated financial statements and related notes thereto.



Selected IFRS financial
data for the years ended May 31, 2010 and 2009 have not been included in this Annual Report on Form 20-F because IFRS financial
statements for such periods have not previously been prepared and could not be prepared without unreasonable effort and expense.
We changed our basis of accounting to IFRS beginning with the quarter ended August 31, 2011. Prior to the adoption of IFRS, we
prepared financial statements in accordance with accounting principles generally accepted in the United States for purposes of
our SEC reporting.



The following table
presents a summary of our consolidated statement of operations derived from our audited Consolidated Financial Statements for
the fiscal years ended May 31, 2013, 2012 and 2011.



Consolidated statements of operations data



|(In thousands, except per share data)                |  |                  |        |   |                  |   |        |                  | 
|---------------------------------------------------- |  | ---------------- | ------ | - | ---------------- | - | ------ | ---------------- | 
|                                                     |  | May
    31, 2013 |        |   | May
    31, 2012 |   |        | May
    31, 2011 | 
|In accordance with IFRS                              |  |                  |        |   |                  |   |        |                  | 
|Revenue                                              |  | $                | —      |   |                  | $ | —      |                  | 
|Research and development                             |  | $                | 3,317  |   |                  | $ | 2,170  |                  | 
|General and administrative                           |  | $                | 2,272  |   |                  | $ | 2,430  |                  | 
|Operating expenses                                   |  | $                | 5,589  |   |                  | $ | 4,600  |                  | 
|Finance expense                                      |  | $                | 6      |   |                  | $ | 20     |                  | 
|Finance income                                       |  | $                | (30    | ) |                  | $ | (6     | )                | 
|Net loss                                             |  | $                | (5,565 | ) |                  | $ | (4,614 | )                | 
|Basic and diluted loss per Common Share              |  | $                | (0.13  | ) |                  | $ | (0.23  | )                | 
|Weighted average number of Common Shares outstanding |  |                  | 42,251 |   |                  |   | 20,260 |                  | 



2







The following table
presents a summary of our consolidated balance sheet as at May 31, 2013, 2012 and 2011. We publish our consolidated financial
statements in Canadian (“CDN”) dollars. In this Annual Report, except where otherwise indicated, all amounts
are stated in CDN dollars.



Consolidated balance sheet data



|(In thousands, except per share data) |  | As at May 31, |       
|------------------------------------- |  | ------------- | ------
|                                      |  | 2013          |       
|In accordance with IFRS               |  |               |       
|Cash and cash equivalents             |  | $             | 653   
|Total assets                          |  | $             | 1,035 
|Total debt                            |  | $             | 1,816 
|Total shareholders’ equity (deficit)  |  | $             | (781  
|Number of Common Shares outstanding   |  |               | 42,251
|Dividends paid on Common Shares       |  |               | —     



The following table
sets out the exchange rates of CDN$ for US$1.00 for the following periods as taken from the Bank of Canada’s website:



|Period                         |  | Average Close |       
|------------------------------ |  | ------------- | ------
|Month Ended April 30, 2014     |  |               | 1.0990
|Fiscal Year Ended May 31, 2013 |  |               | 1.0042
|Fiscal Year Ended May 31, 2012 |  |               | 1.0005
|Fiscal Year Ended May 31, 2011 |  |               | 1.0066
|Fiscal Year Ended May 31, 2010 |  |               | 1.0635
|Fiscal Year Ended May 31, 2009 |  |               | 1.1567



The following table sets forth the high
and low exchange rates for each month during the previous six months.



|Period        |  | High |        |  | Low |  
|------------- |  | ---- | ------ |  | --- | -
|April 2014    |  | $    | 1.0857 |  |     | $
|March 2014    |  | $    | 1.0955 |  |     | $
|February 2014 |  | $    | 1.0939 |  |     | $
|January 2014  |  | $    | 1.0974 |  |     | $
|December 2013 |  | $    | 1.0669 |  |     | $
|November 2013 |  | $    | 1.0509 |  |     | $



B.           Capitalization
and indebtedness.



Not applicable.



C.           Reasons
for the offer and use of proceeds.



Not applicable.



D.           Risk
factors.



3







Investing in our securities
involves a high degree of risk. Before making an investment decision with respect to our Common Shares, you should carefully consider
the following risk factors, in addition to the other information included or incorporated by reference in this Annual Report.
Additional risks not currently known by us or that we consider immaterial at the present time may also impair our business, financial
condition, prospects or results of operations. If any of the following risks occur, our business, financial condition, prospects
or results of operations would likely be materially adversely affected. In that case, the trading price of our Common Shares could
decline and you may lose all or part of the money you paid to buy our Common Shares. The risks set out below are not the only
risks and uncertainties we currently face; other risks may arise in the future.



RISKS RELATED TO
OUR BUSINESS



We are an early
stage development company.



We are at an early
stage of development. Since our incorporation, none of our potential products has obtained regulatory approval for commercial
use and sale in any country, except for Virulizin, for which we have no control over commercialization efforts. We currently do
not receive any revenue from sales of Virulizin. As such, no significant revenues have resulted from product sales. Significant
additional investment will be necessary to complete the development of any of our product candidates. Preclinical and clinical
trial work must be completed before our potential products could be ready for use within the markets that we have identified.
We may fail to develop any products, obtain regulatory approvals, enter clinical trials or commercialize any products. We do not
know whether any of our potential product development efforts will prove to be effective, meet applicable regulatory standards,
obtain the requisite regulatory approvals, be capable of being manufactured at a reasonable cost or be accepted in the marketplace.
We also do not know whether sales, license fees or related royalties will allow us to recoup any investment we make in the commercialization
of our products.



The product candidates
we are currently developing are not expected to be commercially viable for at least the next several years and we may encounter
unforeseen difficulties or delays in commercializing our product candidates. In addition, our potential products may not be effective
or may cause undesirable side effects.



Our
product candidates require significant funding to reach regulatory approval assuming positive clinical results. For example,
our lead product candidate LOR-253, has recently completed a Phase I clinical trial in patients with solid tumors, and we
have reported initial results. Additional funding or a partnership will be necessary to complete, if required, a Phase II
or Phase III clinical trial. Such funding may be very difficult, or impossible to raise in the public or private markets or
through partnerships. If funding or partnerships are not attainable, the development of these product candidates may be
significantly delayed or stopped altogether. The announcement of a delay or discontinuation of development would likely have
a negative impact on our share price.



We need to raise
additional capital.



We have an ongoing
need to raise additional capital. To obtain the necessary capital, we must rely on some or all of the following: additional share
issues, debt issuances (including promissory notes), collaboration agreements or corporate partnerships and grants and tax credits
to provide full or partial funding for our activities. Additional funding may not be available on terms that are acceptable to
us or in amounts that will enable us to carry out our business plan.



Our need for capital
may require us to:



| | · | engage
                                         in equity financings that could result in significant dilution to existing investors;
| | - | -------------------------------------------------------------------------------------------------------------------------------------



| | · | delay
                                         or reduce the scope of or eliminate one or more of our development programs;
| | - | ---------------------------------------------------------------------------------------------------------------------------



| | · | obtain
                                         funds through arrangements with collaborators or others that may require us to relinquish
                                         rights to technologies, product candidates or products that we would otherwise seek to
                                         develop or commercialize ourselves; or license rights to technologies, product candidates
                                         or products on terms that are less favourable to us than might otherwise be available;
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | considerably
                                         reduce operations; or
| | - | ---------------------------------------------------------------------------



| | · | cease
                                         our operations.
| | - | --------------------------------------------------------------



4







We have a history
of operating losses. We expect to incur net losses and we may never achieve or maintain profitability.



We have not been profitable
since our inception in 1986. Under IFRS, we reported net losses of $5.6 million and $4.6 million for the fiscal years ended May
31, 2013 and 2012, respectively, and as of May 31, 2013, we had an accumulated deficit of $200 million.



We have not generated
any significant revenue to date and it is possible that we will never have sufficient product sales revenue to achieve profitability.
We expect to continue to incur losses for at least the next several years as we or our collaborators and licensees pursue clinical
trials and research and development efforts. To become profitable, we, either alone or with our collaborators and licensees, must
successfully develop, manufacture and market our current product candidate LOR-253 as well as continue to identify, develop, manufacture
and market new product candidates. It is possible that we will never have significant product sales revenue or receive royalties
on our licensed product candidates. If funding is insufficient at any time in the future, we may not be able to develop or commercialize
our products, take advantage of business opportunities or respond to competitive pressures.



We may be unable
to obtain partnerships for our product candidates, which could curtail future development and negatively affect our share price.
In addition, our partners might not satisfy their contractual responsibilities or devote sufficient resources to our partnership.



Our strategy for the
research, development and commercialization of our products requires entering into various arrangements with corporate collaborators,
licensors, licensees and others, and our commercial success is dependent upon these outside parties performing their respective
contractual responsibilities. The amount and timing of resources that such third parties will devote to these activities may not
be within our control. These third parties may not perform their obligations as expected and our collaborators may not devote
adequate resources to our programs. In addition, we could become involved in disputes with our collaborators, which could result
in a delay or termination of the related development programs or result in litigation. We intend to seek additional collaborative
arrangements to develop and commercialize some of our products. We may not be able to negotiate collaborative arrangements on
favourable terms, or at all, in the future, and our current or future collaborative arrangements may not be successful.



If we cannot negotiate
collaboration, licence or partnering agreements, we may never achieve profitability and we may not be able to continue to develop
our product candidates. Phase II and Phase III clinical trials for LOR-253 would require significant amounts of funding and
such funding may not be available to us.



Clinical trials
are long, expensive and uncertain processes and Health Canada or the United States Food and Drug Administration (“FDA”)
may ultimately not approve any of our product candidates. We may never develop any commercial drugs or other products that generate
revenues.



None of our product candidates has received
regulatory approval for commercial use and sale in North America, other than Virulizin. We cannot market a pharmaceutical product
in any jurisdiction until it has completed thorough preclinical testing and clinical trials in addition to that jurisdiction’s
extensive regulatory approval process. Approval in one country does not assure approval in another country. In general, significant
research and development and clinical studies are required to demonstrate the safety and effectiveness of our product candidates
before we can submit any regulatory applications.



Clinical trials are long, expensive
and uncertain processes. Clinical trials may not be commenced or completed on schedule and Health Canada or the FDA or any
other regulatory body may not ultimately approve our product candidates for commercial sale. The clinical trials of any of
our drug candidates could be unsuccessful, which would prevent us from advancing, commercializing or partnering the drug.



Even if the results of our preclinical
studies or clinical trials are initially positive, it is possible that we will obtain different results in the later stages of
drug development or that results seen in clinical trials will not continue with longer term treatment. Positive results in Phase
I clinical trials may not be repeated in larger Phase II or Phase III clinical trials.



5







Our preclinical studies and clinical trials
may not generate positive results that will allow us to move towards the commercial use and sale of our product candidates. Furthermore,
negative preclinical or clinical trial results may cause our business, financial condition, or results of operations to be materially
adversely affected. For example, as our lead product candidate LOR-253 has completed the Phase I testing in patients with solid
tumors, for which we previously reported initial data, there is still a long development path ahead which will take many years
to complete and like all of our potential drug candidates is prone to the risks of failure inherent in drug development.



Preparing, submitting and advancing applications
for regulatory approval is complex, expensive and time intensive and entails significant uncertainty. A commitment of substantial
resources to conduct time-consuming research, preclinical studies and clinical trials is required if we are to complete development
of our products.



Later stage clinical trials of our products
require that we identify and enroll a large number of patients with the illness under investigation. We may not be able to enroll
a sufficient number of appropriate patients to complete our clinical trials in a timely manner, particularly in smaller indications
and indications where this is significant competition for patients. If we experience difficulty in enrolling a sufficient number
of patients to conduct our clinical trials, we may need to delay or terminate ongoing clinical trials and will not accomplish
objectives material to our success. Delays in planned patient enrolment or lower than anticipated event rates in our current clinical
trials or future clinical trials also may result in increased costs, program delays, or both.



In addition, unacceptable toxicities or
adverse side effects may occur at any time in the course of preclinical studies or human clinical trials or, if any product candidates
are successfully developed and approved for marketing, during commercial use of any approved products. The appearance of any unacceptable
toxicities or adverse side effects could interrupt, limit, delay or abort the development of any of our product candidates or,
if previously approved, necessitate their withdrawal from the market. Furthermore, disease resistance or other unforeseen factors
may limit the effectiveness of our potential products.



Our failure to develop safe, commercially
viable drugs would substantially impair our ability to generate revenues and sustain our operations and would materially harm
our business and adversely affect our share price.



We have agreed
to indemnify our predecessor, Old Lorus, and its directors, officers and employees.



In connection with
the reorganization that we undertook in fiscal year 2008, we have agreed to indemnify our predecessor, Old Lorus, and its directors,
officers and employees from and against all damages, losses, expenses (including fines and penalties), other third party costs
and legal expenses, to which any of them may be subject arising out of any matter occurring:



| | · | prior
                                         to, at or after the effective time of the arrangement transaction, and directly or indirectly
                                         relating to any of the assets of Old Lorus transferred to us pursuant to the arrangement
                                         transaction (including losses for income, sales, excise and other taxes arising in connection
                                         with the transfer of any such asset) or conduct of the business prior to the effective
                                         time of the arrangement;
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | prior
                                         to, at or after the effective time as a result of any and all interests, rights, liabilities
                                         and other matters relating to the assets transferred by Old Lorus to us under the arrangement;
                                         and
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | prior
                                         to or at the effective time and directly or indirectly relating to, with certain exceptions,
                                         any of the activities of Old Lorus or the arrangement.
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



This indemnification
obligation could result in significant liability to us. To date no amount has been claimed on this indemnification obligation.
Should a claim arise under this indemnification obligation it could result in significant liability to the Company which could
have a negative impact on our liquidity, financial position, and ability to obtain future funding among other things.



6







We may not achieve
our projected development goals in the time frames we announce and expect.



We set goals for,
and make public statements regarding, the expected timing of the accomplishment of objectives material to our success, such as
the commencement and completion of clinical trials, the partnership of our product candidates and our ability to secure the financing
necessary to continue the development of our product candidates. The actual timing of these events can vary dramatically due to
factors within and beyond our control, such as delays or failures in our clinical trials, the uncertainties inherent in the regulatory
approval process, market conditions and interest by partners in our product candidates among other things. Our clinical trials
may not be completed, and we may not make regulatory submissions or receive regulatory approvals as planned, or that we will secure
partnerships for any of our product candidates. Any failure to achieve one or more of these milestones as planned would have a
material adverse effect on our business, financial condition and results of operations.



As a result
of intense competition and technological change in the pharmaceutical industry, the marketplace may not accept our products or
product candidates, and we may not be able to compete successfully against other companies in our industry and achieve profitability.



Many of our competitors
have:



| | · | drug
                                         products that have already been approved or are in development, and operate large, well-funded
                                         research and development programs in these fields;
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | substantially
                                         greater financial and management resources, stronger intellectual property positions
                                         and greater manufacturing, marketing and sales capabilities, areas in which we have limited
                                         or no experience; and
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | significantly
                                         greater experience than we do in undertaking preclinical testing and clinical trials
                                         of new or improved pharmaceutical products and obtaining required regulatory approvals.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Consequently, our
competitors may obtain Health Canada FDA and other regulatory approvals for product candidates sooner and may be more successful
in manufacturing and marketing their products than we or our collaborators are.



Our competitor’s
existing and future products, therapies and technological approaches will compete directly with the products we seek to develop.
Current and prospective competing products may be more effective than our existing and future products insofar as they may provide
greater therapeutic benefits for a specific problem or may offer easier delivery or comparable performance at a lower cost.



Any product candidate
that we develop and that obtains regulatory approval must then compete for market acceptance and market share. Our product candidates
may not gain market acceptance among physicians, patients, healthcare payers, insurers, the medical community and other stakeholders.
Further, any products we develop may become obsolete before we recover any expenses we incurred in connection with the development
of these products. As a result, we may never achieve profitability.



If we fail to
attract and retain key employees, the development and commercialization of our products may be adversely affected.



We depend on the principal
members of our scientific and management staff. If we lose any of these persons, our ability to develop products and become profitable
could suffer. The risk of being unable to retain key personnel may be increased by the fact that we have not executed long-term
employment contracts with our employees, except for our senior executives. Our future success will also depend in large part on
our ability to attract and retain other highly qualified scientific and management personnel. We face competition for personnel
from other companies, academic institutions, government entities and other organizations.



We may be unable
to obtain patents to protect our technologies from other companies with competitive products, and patents of other companies could
prevent us from manufacturing, developing or marketing our products.



7







Patent protection



The patent positions
of pharmaceutical and biotechnology companies are uncertain and involve complex legal and factual questions. The United States
Patent and Trademark Office and many other patent offices in the world have not established a consistent policy regarding the
breadth of claims that they will allow in biotechnology patents.



Allowable patentable
subject matter and the scope of patent protection obtainable may differ between jurisdictions. If a patent office allows broad
claims, the number and cost of patent interference proceedings in the United States, or analogous proceedings in other jurisdictions
and the risk of infringement litigation may increase. If it allows narrow claims, the risk of infringement may decrease, but the
value of our rights under our patents, licenses and patent applications may also decrease.



The scope of the claims
in a patent application can be significantly modified during prosecution before the patent is issued. Consequently, we cannot
know whether our pending applications will result in the issuance of patents or, if any patents are issued, whether they will
provide us with significant proprietary protection or will be circumvented, invalidated or found to be unenforceable.



Publication of discoveries
in scientific or patent literature often lags behind actual discoveries. Patent applications filed in the United States generally
will be published 18 months after the filing date unless the applicant certifies that the invention will not be the subject of
a foreign patent application. In many other jurisdictions, such as Canada, patent applications are published 18 months from the
priority date. We may not be aware of such literature. Accordingly, we cannot be certain that the named inventors of our products
and processes were the first to invent that product or process or that we were the first to pursue patent coverage for our inventions.



Enforcement of intellectual property
rights



Protection of the
rights revealed in published patent applications can be complex, costly and uncertain. Our commercial success depends in part
on our ability to maintain and enforce our proprietary rights. If third parties engage in activities that infringe our proprietary
rights, our management’s focus will be diverted and we may incur significant costs in asserting our rights. We may not be
successful in asserting our proprietary rights, which could result in our patents being held invalid or a court holding that the
third party is not infringing, either of which would harm our competitive position.



Others may design
around our patented technology. We may have to participate in interference proceedings declared by the United States Patent and
Trademark Office, European opposition proceedings, or other analogous proceedings in other parts of the world to determine priority
of invention and the validity of patent rights granted or applied for, which could result in substantial cost and delay, even
if the eventual outcome is favourable to us. Our pending patent applications, even if issued, may not be held valid or enforceable.



Trade secrets



We also rely on trade
secrets, know-how and confidentiality provisions in our agreements with our collaborators, employees and consultants to protect
our intellectual property. However, these and other parties may not comply with the terms of their agreements with us, and we
might be unable to adequately enforce our rights or obtain adequate compensation for the damages caused by unauthorized disclosure
or use of our trade secrets or know how. Our trade secrets or those of our collaborators also may be independently discovered
by others.



Our products
and product candidates may infringe the intellectual property rights of others, or others may infringe on our intellectual property
rights which could increase our costs.



Our success also depends
on avoiding infringement of the proprietary technologies of others. In particular, there may be certain issued patents and patent
applications claiming subject matter which we or our collaborators may be required to license in order to research, develop or
commercialize LOR-253, our lead product candidate. In addition, third parties may assert infringement or other intellectual property
claims against us. An adverse outcome in these proceedings could subject us to significant liabilities to third-parties, require
disputed rights to be licensed from third-parties or require us to cease or modify our use of the technology. If we are required
to license third-party technology, a license under such patents and patent applications may not be available on acceptable terms
or at all. Further, we may incur substantial costs defending ourselves in lawsuits against charges of patent infringement or other
unlawful use of another’s proprietary technology.We may also need to bring claims against others who we believe
are infringing our rights in order to become or remain competitive and successful. Any such claims can be time consuming and expensive
to pursue.



8







If product liability,
clinical trial liability or environmental liability claims are brought against us or we are unable to obtain or maintain product
liability, clinical trial or environmental liability insurance, we may incur substantial liabilities that could reduce our financial
resources.



The clinical testing
and commercial use of pharmaceutical products involves significant exposure to product liability, clinical trial liability, environmental
liability and other risks that are inherent in the testing, manufacturing and marketing of our products. These liabilities, if
realized, could have a material adverse effect on the Corporation’s business, results of operations and financial condition.



We have obtained limited
product liability insurance coverage for our clinical trials on humans; however, our insurance coverage may be insufficient to
protect us against all product liability damages. Regardless of merit or eventual outcome, liability claims may result in decreased
demand for a future product, injury to reputation, withdrawal of clinical trial volunteers, loss of revenue, costs of litigation,
distraction of management and substantial monetary awards to plaintiffs. Additionally, if we are required to pay a product liability
claim, we may not have sufficient financial resources to complete development or commercialization of any of our product candidates
and our business and results of operations will be adversely affected. In general, insurance will not protect us against some
of our own actions, such as negligence.



As the Corporation’s
development activities progress towards the commercialization of product candidates, our liability coverage may not be adequate,
and the Corporation may not be able to obtain adequate product liability insurance coverage at a reasonable cost, if at all. Even
if the Corporation obtains product liability insurance, its financial position may be materially adversely affected by a product
liability claim. A product liability claim could also significantly harm the Corporation’s reputation and delay market acceptance
of its product candidates. Additionally, product recalls may be issued at the direction of the FDA, other government agencies
or other companies having regulatory control for pharmaceutical sales. If a product recall occurs in the future, such a recall
could adversely affect our business, financial condition or reputation.



We have no manufacturing
capabilities and face supply risks. We depend on third-parties, including a number of sole suppliers, for manufacturing and storage
of our product candidates used in our clinical trials. Product introductions may be delayed or suspended if the manufacture of
our products is interrupted or discontinued.



Other than limited
quantities for research purposes, we do not have manufacturing facilities to produce supplies of LOR-253 or any of our other product
candidates to support clinical trials or commercial launch of these products, if they are approved. We are dependent on third
parties for manufacturing and storage of our product candidates. If the supply of necessary components is interrupted, components
from alternative suppliers may not be available in sufficient volumes or at acceptable quality levels within required timeframes,
if at all, to meet the needs of the Corporation. An inability to contract for a sufficient supply of our product candidates on
acceptable terms, or delays or difficulties in the manufacturing process or our relationships with our manufacturers, may lead
to us not having sufficient product to conduct or complete our clinical trials or support preparations for the commercial launch
of our product candidates, if approved. This may lead to substantial lost revenue opportunity and contract liability to third
parties.



Reliance on
Licensor(s) to Maintain Patent Rights



The Corporation's
commercial success depends, in part, on maintaining and defending patent rights related to products that the Corporation may market
in the future. Since the Corporation may not fully control the patent prosecution of any licensed patent applications it is possible
that the licensors will not devote the same resources or attention to the prosecution of the licensed patent applications as the
Corporation would if it controlled the prosecution of the applications. The licensors may also not pursue and successfully prosecute,
enforce or defend any potential patent infringement or invalidity claim, may fail to maintain their issued patents or prosecute
or maintain their patent applications, or may pursue any litigation less aggressively than the Corporation would. Consequently,
the resulting patent protection, if any, may not be as strong or comprehensive, which could have a material adverse effect on
the Corporation.



9







Extensive Government
Regulation



Government regulation
is a significant factor in the development, production and marketing of the Corporation’s products. Research and development,
testing, manufacture, marketing and sales of pharmaceutical products or related products are subject to extensive regulatory oversight,
often in multiple jurisdictions, which may cause significant additional costs and/or delays in bringing products to market, and
in turn, may cause significant losses to investors. The regulations applicable to the Corporation's product candidates may change.
Even if granted, regulatory approvals may include significant limitations on the uses for which products can be marketed or may
be conditioned on the conduct of post-marketing surveillance studies. Failure to comply with applicable regulatory requirements
can, among other things, result in warning letters, the imposition of civil penalties or other monetary payments, delay in approving
or refusal to approve a product candidate, suspension or withdrawal of regulatory approval, product recall or seizure, operating
restrictions, interruptions of clinical trials or manufacturing, injunctions or criminal prosecution. In addition, regulatory
agencies many not approve the labeling claims that are necessary or desirable for the successful commercialization of the Corporation’s
product candidates.



Requirements for regulatory
approval vary widely from country to country. Whether or not approved in Canada or the United States, regulatory authorities in
other countries must approve a product prior to the commencement of marketing the product in those countries. The time required
to obtain any such approval may be longer or shorter than in Canada or the United States. Approved drugs, as well as their manufacturers,
are subject to continuing and ongoing review, and discovery of problems with these products or the failure to adhere to manufacturing
or quality control requirements may result in regulatory restrictions being imposed



Risks
Related To Our Common Shares



Our share price
has been and will continue to be volatile and an investment in our Common Shares could suffer a decline in value.



You should consider
an investment in our Common Shares as risky and invest only if you can withstand a significant loss and wide fluctuations in the
market value of your investment. We receive only limited attention by securities analysts and frequently experience an imbalance
between supply and demand for our Common Shares. The market price of our Common Shares has been highly volatile and is likely
to continue to be volatile.This leads to a heightened risk of securities litigation pertaining to such volatility.Factors affecting our Common Share price include but are not limited to:



| | · | our
                                         ability to raise additional capital;
| | - | ---------------------------------------------------------------------------------



| | · | the
                                         progress of our clinical trials:
| | - | -----------------------------------------------------------------------------



| | · | our
                                         ability to obtain partners and collaborators to assist with the future development of
                                         our products;
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | general
                                         market conditions;
| | - | -------------------------------------------------------------------



| | · | announcements
                                         of technological innovations or new product candidates by us, our collaborators or our
                                         competitors;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | published
                                         reports by securities analysts;
| | - | ----------------------------------------------------------------------------------



| | · | developments
                                         in patent or other intellectual property rights;
| | - | ------------------------------------------------------------------------------------------------------



| | · | the
                                         cash and short term investments held us and our ability to secure future financing;
| | - | --------------------------------------------------------------------------------------------------------------------------------



| | · | public
                                         concern as to the safety and efficacy of drugs that we and our competitors develop; and
| | - | ---------------------------------------------------------------------------------------------------------------------------------------



| | · | shareholder
                                         interest in our Common Shares.
| | - | -----------------------------------------------------------------------------------



10







Future sales
of our Common Shares by us or by our existing shareholders could cause our share price to fall.



The issuance of Common
Shares by us could result in significant dilution in the equity interest of existing shareholders and adversely affect the market
price of our Common Shares. Sales by existing shareholders of a large number of our Common Shares in the public market and the
issuance of Common Shares issued in connection with strategic alliances, or the perception that such additional sales could occur,
could cause the market price of our Common Shares to decline and have an undesirable impact on our ability to raise capital.



We are susceptible
to stress in the global economy and therefore, our business may be affected by the current and future global financial condition.



If the increased level
of volatility and market turmoil that have marked recent years continue, our operations, business, financial condition and the
trading price of our Common Shares could be materially adversely affected. Furthermore, general economic conditions may have a
great impact on us, including our ability to raise capital, our commercialization opportunities and our ability to establish and
maintain arrangements with others for research, manufacturing, product development and sales.



An active trading
market in our Common Shares may not be sustained.



Our Common Shares
are listed for trading on the Toronto Stock Exchange. However, an active trading market in our Common Shares on the stock exchange
may not be sustained and we may not be able to maintain our listing.



There is a limited
market for our Common Shares in the United States.



There currently is
a limited market for our Common Shares in the United States. If shareholders in the United States are unable to sell their Common
Shares in the United States, they may have to sell their Common Shares over the Toronto Stock Exchange (the “TSX”),
which may expose the selling shareholders to currency exchange risk. In addition, because we are not listed on any United States
stock exchange, resales of our Common Shares to United States residents under state securities or “blue sky” laws
are likely to be limited to unsolicited transactions.



It may be difficult
for non-Canadian investors to obtain and enforce judgments against us because of our Canadian incorporation and presence.



We are a corporation
existing under the laws of Canada. Many of our directors and officers, and all of the experts named in this Annual Report and
the documents incorporated by reference into this Annual Report, are residents of Canada, and all or a substantial portion of
their assets, and a substantial portion of our assets, are located outside the United States. Consequently, although we have appointed
an agent for service of process in the United States, it may be difficult for holders of our shares who reside in the United States
to effect service within the United States upon our directors and officers and experts who are not residents of the United States.
It may also be difficult for holders of our shares who reside in the United States to realize in the United States upon judgments
of courts of the United States predicated upon our civil liability and the civil liability of our directors, officers and experts
under the United States federal securities laws. Investors should not assume that Canadian courts (i) would enforce judgments
of United States courts obtained in actions against us or our directors, officers or experts predicated upon the civil liability
provisions of the United States federal securities laws or the securities or “blue sky” laws of any state within the
United States or (ii) would enforce, in original actions, liabilities against us or our directors, officers or experts predicated
upon the United States federal securities laws or any such state securities or “blue sky” laws. In addition, we have
been advised by our Canadian counsel that in normal circumstances, only civil judgments and not other rights arising from United
States securities legislation are enforceable in Canada and that the protections afforded by Canadian securities laws may not
be available to investors in the United States.



11







We are likely
a “passive foreign investment company” which may have adverse U.S. federal income tax consequences for U.S. shareholders.



U.S. investors in
our Common Shares should be aware that the Company believes it was classified as a passive foreign investment company (“PFIC”)
during the tax year ended May 31, 2013, and based on current business plans and financial expectations, the Company believes that
it will be a PFIC for the current tax year. If the Company is a PFIC for any year during a U.S. shareholder’s holding period,
then such U.S. shareholder generally will be required to treat any gain realized upon a disposition of Common Shares, or any so-called
“excess distribution” received on its Common Shares, as ordinary income, and to pay an interest charge on a portion
of such gain or distributions, unless the shareholder makes a timely and effective “qualified electing fund” election
(“QEF Election”) or a “mark-to-market” election with respect to the Common Shares. A U.S. shareholder
who makes a QEF Election generally must report on a current basis its share of the Company’s net capital gain and ordinary
earnings for any year in which the Company is a PFIC, whether or not the Company distributes any amounts to its shareholders.
However, U.S. shareholders should be aware that we may not satisfy record keeping requirements that apply to a qualified electing
fund, and we may not supply U.S. shareholders with information that such U.S. shareholders require to report under the QEF Election
rules, in the event that we are a PFIC and a U.S. shareholder wishes to make a QEF Election. Thus, U.S. shareholders may not be
able to make a QEF Election with respect to their Common Shares. A U.S. shareholder who makes the mark-to-market election generally
must include as ordinary income each year the excess of the fair market value of the Common Shares over the taxpayer’s basis
therein. This paragraph is qualified in its entirety by the discussion below under the heading “Certain United States Federal
Income Tax Considerations.” Each U.S. shareholder should consult its own tax advisor regarding the U.S. federal, U.S. local,
and foreign tax consequences of the PFIC rules and the acquisition, ownership, and disposition of our Common Shares.



Item 4.          Information
on the Company



| | A. | History and development of the company.
| | -- | ---------------------------------------



Old Lorus was incorporated
under the Business Corporations Act(Ontario) on September 5, 1986 under the name RML Medical Laboratories Inc. On October
28, 1991, RML Medical Laboratories Inc. amalgamated with Mint Gold Resources Ltd., resulting in Old Lorus becoming a reporting
issuer (as defined under applicable securities law) in Ontario, on such date. On August 25, 1992, Old Lorus changed its name to
IMUTEC Corporation. On November 27, 1996, Old Lorus changed its name to Imutec Pharma Inc., and on November 19, 1998, Old Lorus
changed its name to Lorus Therapeutics Inc. On October 1, 2005, Old Lorus continued under the Canada Business Corporations
Act.



On the Arrangement
Date, Old Lorus completed a plan of arrangement and corporate reorganization with, among others, 6650309 Canada Inc. (“New
Lorus”), 6707157 Canada Inc. and Pinnacle International Lands, Inc. As a result of the plan of arrangement and reorganization,
each Common Share of Old Lorus was exchanged for one Common Share of New Lorus. New Lorus continued the business of Old Lorus
after the Arrangement Date with the same officers and employees and continued to be governed by the same board of directors as
Old Lorus prior to the Arrangement Date.



The address of the
Company’s head and registered office is 2 Meridian Road, Toronto, Ontario, Canada, M9W 4Z7 and our phone number is (416)
798-1200. Our corporate website is www.lorusthera.com. The contents of the website and items accessible through the website are
specifically not incorporated in this Annual Report by reference.



Lorus’ subsidiary
is NuChem Pharmaceuticals Inc. (“NuChem”), a corporation incorporated under the laws of Ontario, of which Lorus
owns 80% of the issued and outstanding voting share capital and 100% of the issued and outstanding non-voting preference share
capital.



Our Common Shares are listed on the TSX
under the symbol “LOR”.



12







Lorus is a clinical stage biotechnology
company with a commitment to discovering and developing targeted therapies addressing unmet medical needs in oncology. We aim
to develop therapeutics focused on novel cellular targets on the leading edge of cancer research coupled to companion diagnostics
to identify the optimal patient population for our products. Our pipeline of cancer drug candidates includes small molecule products
and immunotherapies providing additive or synergistic efficacy without leading to overlapping toxicities with existing anti-cancer
regimens, facilitating the adoption of doublet or possibly triplet therapies.



Our success is dependent
upon several factors, including recruitment and retention of skilled personnel, maintaining sufficient levels of funding through
public and/or private financing, establishing the efficacy and safety of our drug candidates in clinical trials, securing strategic
partnerships and obtaining the necessary regulatory approvals to market our products.



We believe the future
of cancer treatment and management lies in selecting for treatment patients having cancers that are predisposed to response based
on a drug’s unique mechanism of action. Our opinion is that many drugs currently approved for the treatment and management
of cancer are not selective for the specific genetic alterations (targets) that cause the patient’s tumor and hence lead
to significant toxicities due to off-target effects. Lorus’ strategy is to continue the development of our product pipeline
across several therapeutic indications in oncology with therapeutics addressing novel targets that drive particular types of cancers.
We also strive to optimize our therapeutics for synergy with currently available, commercialized therapeutics for a drug combination
regimen with enhanced efficacy. We evaluate the merits of each drug candidate throughout the clinical trial process and will consider
partnering a program when appropriate.







Capital Expenditures and Divestitures



Not applicable.



13







| | B. | Business overview.
| | -- | ------------------



Lorus is a clinical
stage biotechnology company with a commitment to discovering and developing targeted therapies addressing unmet medical needs
in oncology. We aim to develop therapeutics focused on novel cellular targets on the leading edge of cancer research coupled to
companion diagnostics to identify the optimal patient population for our products. Our pipeline of cancer drug candidates includes
small molecule products and immunotherapies providing additive or synergistic efficacy without leading to overlapping toxicities
with existing anti-cancer regimens, facilitating the adoption of doublet or possibly triplet therapies.



We believe the future
of cancer treatment and management lies in the prospective selection and treatment of patients predisposed to response based on
a drug’s unique mechanism of action. We are of the view that many drugs currently approved for the treatment and management
of cancer are not selective for the specific genetic alterations (targets) that cause the patient’s tumor and hence lead
to significant toxicities due to off-target effects. Lorus’ strategy is to continue the development of our programs that
address a common underlying pathway within a patient population, and we intend to apply this strategy across several therapeutic
indications in oncology, including hematologic malignancies and solid tumor indications. Our lead program, LOR-253, is a first-in-class
inducer of the Krüppel-like factor 4 gene (the “Klf4 Gene”) for patients with advanced hematologic malignancies,
including acute myeloid leukemia (“AML”) and myelodysplastic syndromes (“MDS”).



Krüppel-Like Factor 4 & CDX2



Krüppel-like
factors constitute a diverse family of genes (the “Klf Genes”) that act by modifying the expression levels
of other genes that control essential cellular processes such as proliferation, migration, differentiation, cell death and metastasis.
Approximately 17 Klf Genes are known, with an array of roles that include serving as innate tumor suppressors. The Klf Genes give
rise to the production of proteins (the “KLF Proteins”). Structurally, KLF Proteins include DNA binding domains
that allow for the identification and regulation of other genes. Of particular importance, the Krüppel-like factor 4 protein
(the “KLF4 Protein”) is also reported to be impacted by the embryonic gene, Cdx2 (the “Cdx2 Gene”).



The Cdx2 Gene, while
not activated in the bone marrow and blood cells of normal adults, was observed to be activated in the malignant cells in a majority
of patients with AML. It has subsequently been noted that the gene product of the Cdx2 Gene, the protein CDX2 (the “CDX2
Protein”), had the most profound intracellular impact on KLF4 Protein levels by binding, and epigenetically silencing
the Klf4 Gene (Faber et. al., J Clin Invest. 2013;123(1):299–314). In other words, while the sequence of the bases in the
DNA in the gene remain intact, those bases are modified chemically to reduce the expression of the gene. In subsequent studies
from Faber et. al., it was demonstrated that induction of the Cdx2 Gene, in cells lacking CDX2 Protein, subsequently decreased
KLF4 Protein levels and promoted proliferation (Figure 1, First Bullet), while silencing the Cdx2 Gene in cells possessing CDX2
Protein alleviated the suppression of the Klf4 Gene and restored innate function (Figure 1, Second Bullet) to drive cellular apoptosis
(programmed cell death) in AML cells. Further, in cells possessing an active Cdx2 Gene, Faber et. al. inserted an active Klf4
Gene to overcome innate KLF4 Protein suppression, and revealed that increased KLF4 Protein promoted apoptosis (Figure 1, Third
Bullet).



14







Figure 1: Studies Assessing the Role
of KLF4 in AML Cells







It has been suggested
by Faber et. al. that a multitude of genetic abnormalities culminate in the aberrant expression of the Cdx2 Gene and ultimately
converge on decreased Klf4 Gene transcription to yield diminished KLF4 Protein levels. This CDX2 Protein-KLF4 Protein signature
was speculated by Faber et. al. to be a potential trigger for AML based on the aforementioned pro-proliferative outcomes of diminished
KLF4 levels and the absence of this protein signature in healthy patient samples. Notably, it was observed by Scholl et. al. in
2007 (J. Clin. Invest. 117:1037–1048 (2007) that approximately 40% of patients with higher risk MDS possessed increased
CDX2 Protein levels, and may represent the portion of the MDS population progressing to AML. Other opportunities in oncology in
which the Klf4 Gene has been implicated to play a role include colorectal, gastric, cervical, prostate and lung cancers, among
others.



LOR-253: Lead Clinical Program



Our lead program is
LOR-253, a small molecule found to induce the transcription of the Klf4 Gene in vitro studies. LOR-253 was discovered and identified
by Lorus scientists based upon the magnitude of its antiproliferative and anti-metastatic activity across a multitude of cell
lines. In vitro studies conducted at Lorus have demonstrated significant potency (nanomolar IC50 concentrations) of LOR-253 in
AML cell lines, and ten to 1000 times greater potency than in solid tumor cell lines. In vitro analyses with relevant AML cell
lines, including THP1, HL-60 and Kasumi-1, have demonstrated that LOR-253 led to significant elevation of KLF4 Protein levels,
with the anticipated increase in cyclin-dependent kinase inhibitor 1 (p21, a protein that halts the cell cycle and prevents cells
from proliferating), caspase-3 (an enzyme activated during programmed cell death to chop up other proteins), and Annexin-V (a
protein used as a marker for the initiation of programmed cell death), leading to G1 cell cycle arrest and apoptosis (programmed
cell death). LOR-253 is administered as an intravenous infusion in patients. We have reported initial results from a Phase I clinical
study of LOR-253 in patients with various solid tumors which indicated that LOR- 253 was safe and well tolerated with indications
of anti-tumor activity as a single agent. Our plans are to advance LOR-253 to a Phase Ib clinical study in relapsed / refractory
hematologic malignancies, including patients with AML, MDS and various lymphomas, based upon the common underlying, leukemia-causing
profile of Klf4 Gene suppression. The development of LOR-253 currently represents the main focus of Lorus.



Lorus is currently
pursuing the clinical development of LOR-253 in AML, based on in vitro data demonstrating significant sensitivity to AML cell
lines and recent academic research implicating up-regulation of the CDX2 Protein, and suppression of the KLF4 Protein, as a possible
leukemogenic trigger in AML. This CDX2 Protein-KLF4 Protein signature has been observed to be absent in the normal hematopoietic
stem and progenitor cells of healthy individuals. The CDX2 Protein is reported by Faber et. al. to epigenetically silence the
Klf4 Gene tumor suppressor as a critical oncogenic event (transforming normal cells to cancer cells) in AML, and LOR-253 has demonstrated
the ability in preclinical investigations to up-regulate the Klf4 Gene and induce tumor-killing effect. We believe these findings
warrant investigation of the potential clinical utility of LOR-253 in the treatment of patients with suppressed Klf4 Gene in AML,
MDS, and, potentially, other hematologic malignancies.



15







Lorus is currently
developing and validating a companion diagnostic for LOR-253. The diagnostic will assess the extent of genetic expression of Cdx2
and Klf4 in patients as a potential predictor of response to therapy with LOR-253, as well as assess post-treatment expression
levels as biomarkers of efficacy.



Acute Myeloid Leukemia



AML is a rapidly progressing
cancer of the blood and bone marrow characterized by the uncontrolled proliferation of dysfunctional myeloblasts that do not mature
into healthy blood cells. It is the most common form of acute leukemia in adults. The American Cancer Society estimates there
were approximately 14,590 new cases of AML and approximately 10,370 deaths from AML in the U.S. in 2013 and that there will be
approximately 18,860 new cases of AML and approximately 10,460 deaths from AML in the U.S. in 2014.Standard induction
therapy with chemotherapy is successful in many AML patients, but the majority of these patients will relapse with treatment refractory
disease. Typical relapse rates in patients less than, and greater than, 60 years of age are approximately 48%and 71%respectively,
as reported by Datamonitor Healthcare



Myelodysplastic Syndromes



MDS are a group of
blood and bone marrow disorders. In MDS, stem cells do not mature normally, and the number of blasts (immature cells) and dysplastic
(abnormally developed) cells increases. Also, the number of healthy mature cells decreases, meaning there are fewer normal red
blood cells, white blood cells, and platelets. The numbers of blood cells are often called blood cell counts. Because of the decrease
in healthy cells, people with MDS often have anemia (a lowered blood cell count), and may have neutropenia (a low white blood
cell count) and thrombocytopenia (a low platelet count). Also, the chromosomes (long strands of genes) in the bone marrow cells
may be abnormal. According to the American Cancer Society, there are approximately 13,000 new cases of MDS annually in the US.
Additionally, Datamonitor Healthcare reports median survival in higher risk MDS patients may range between five months and two
years. There are several subtypes of MDS, and some subtypes of MDS may eventually turn into AML.



Solid Tumors



Phase 1 data with
LOR-253 in patients with solid tumors and extensive preclinical data in solid tumor cells, including non-small cell lung cancer
(“NSCLC”), have identified an opportunity for LOR-253 in patients possessing cancers with reduced Klf4 Gene
expression. Our prior Phase 1 study with LOR-253 also exhibited a favorable safety profile for LOR-253 without an identified maximally
tolerated dose over a 28-day cycle. Various solid tumors have exhibited suppressed levels of Klf4 Gene in scientific publications,
including colorectal, gastric, pancreatic and cervical cancers, as well as NSCLC. NSCLC is an indication that we consider to have
a large market potential and important unmet need worldwide, in which the Klf4 Gene is a tumor suppressor that is present in case-matched
normal cells but depressed in NSCLC tumor cells. Lorus may evaluate the clinical utility of LOR-253 in additional studies in a
subset of NSCLC patients that may be predisposed to a response with a therapeutic activating the Klf4 Gene.



Undisclosed
Program



In April 2013, Lorus
entered into a research and license option agreement with Elanco, the animal health division of Eli Lilly and Company (“Elanco”),
to investigate a new proprietary series of Lorus’ compounds for veterinary medicine. Pursuant to the agreement, Elanco will
fund the research program and was granted an exclusive option to license the worldwide rights for selected compounds for veterinary
use; the terms of which will be negotiated if the option is exercised by Elanco. Lorus retains the rights to develop and commercialize
these compounds for human use and intends to use the animal data from the collaboration as a basis for a partnership with a third
party that will seek to develop the technology for the treatment of patients with cancer. Lead optimization is underway and the
next goal is to identify a clinical drug candidate which can be developed for both human and animal use.



16







Subsequent Events



June 2013 Private Placement



In June 2013,
Lorus completed a private placement of units consisting of (i) $ 1,000 principal amount of unsecured promissory notes; and
(ii) 1,000 Common Share purchase warrants at a price of $ 1,000 per unit, for aggregate gross proceeds of $893,000.



Strategic Review Process



On September 12, 2013,
the Corporation formed a special committee, the Special Committee, composed of independent directors to review strategic alternatives
available to the Corporation, designed to secure the long-term financial and operational sustainability of the Corporation with
a view to enhance shareholder value. On October 28, 2013, the Special Committee, after having considered and reviewed a number
of options, concluded its review. The Special Committee recommended that the board of directors of Lorus (the “Board”)
approve the appointments of William G. Rice, Ph.D. as Chief Executive Officer and Chairman of the Board and of Daniel D. Von Hoff,
M.D., to serve as a special advisor to fulfill the functions of the Corporation’s Senior Vice President of Medical Affairs.



September 2013 Private Placement



On September 26, 2013, the Corporation
completed a private placement of convertible promissory notes for aggregate gross proceeds of $600,000 to maintain the research
and development activities of the Corporation while the Special Committee was continuing to review strategic alternatives available
to the Corporation. An additional $150,000 was raised subsequently under unsecured non-convertible loans.



Changes in Management



On October 28, 2013,
William G. Rice, Ph.D., was appointed as Chief Executive Officer of the Corporation and Chairman of the Board, while former Chief
Executive Officer of the Corporation, Dr. Aiping Young, continued as President and Chief Operating Officer until she departed
the Corporation on March 18, 2014. On October 28, 2013, Lorus also appointed Daniel D. Von Hoff, M.D., to serve as a special
advisor to fulfill the functions of the Corporation’s Senior Vice President of Medical Affairs. Dr. Von Hoff is an independent
contractor and advisor, but is not an employee of Lorus. The Board, after receiving the recommendation of the Special Committee,
unanimously approved the appointments. In doing so, the Board determined that such appointments were in the best interest of Lorus,
as they were considered to enhance the management team and advisory team with the addition of two seasoned and experienced biotechnology
executives bringing extensive clinical development and capital raising experience and improving the awareness and presence of
the Corporation in the United States. William G. Rice, Ph.D., as the new Chief Executive Officer of the Corporation and Chairman
of the Board, was authorized and mandated by the Board to explore all available options to maximize shareholder value. On April
10, 2014, Dr. Rice was additionally appointed as President of the Corporation.



On October 29, 2013,
Brian Druker, M.D., was appointed as the Chair of the Corporation’s Scientific Advisory Board. Like Dr. Von Hoff, Dr. Druker
is an independent contractor and advisor, but not any employee of Lorus.



On December 2, 2013,
Avanish Vellanki was appointed as Chief Business Officer of the Corporation to manage global business development, licensing and
corporate strategy, and Gregory K. Chow was appointed as Chief Financial Officer of the Corporation and assumed global responsibility
for corporate finance and accounting functions for the Corporation. On April 10, 2014, Mssrs. Vellanki and Chow were additionally
appointed as Senior Vice Presidents of the Corporation.



17







December 2013 Public Offering and Over
Allotment



On December 10, 2013,
the Company completed a public offering of Common Shares. The Company issued a total of 12,730,000 Common Shares at a purchase
price of $0.55 per Common Share, for aggregate gross proceeds of $7,001,500.



In January 2014, the
underwriters exercised in full their over-allotment option to purchase an additional 1,909,500 Common Shares of the Company at
a purchase price of $0.55 per Common Share, in connection with the December 10, 2013 public offering. As a result of the
exercise of this over-allotment option, Lorus received additional gross proceeds of $1,050,225 and raised total gross proceeds
of $8,051,725 from this public offering.



April 2014 Public Offering



In April 2014, the
Company completed a public offering of Common Shares. The Company issued a total of 56,500,000 Common Shares at a purchase price
of $0.50 per Common Share, including 6,500,000 Common Shares sold pursuant to the partial exercise of an over-allotment option,
for aggregate gross proceeds of $28,250,000.



LOR-253 Development



On October 29, 2013,
the Corporation announced that it will pursue the clinical development of LOR-253, its small molecule inducer of the tumor suppressor
KLF4, in AML and other hematologic malignancies.



Agreements



Manufacturing
Agreements



We currently rely
upon subcontractors for the manufacture of our drug candidates. The subcontractors manufacture clinical material according to
current Good Manufacturing Practices, or GMPs, at contract manufacturing organizations that have been approved by our quality
assurance department staff, after having conducted audits to ensure such manufacturers meet the requirements of the relative regulatory
authorities.



Manufactured product
for clinical purposes is tested for conformance with product specifications prior to release by our quality assurance staff. GMP
batches of our drug candidates are subjected to prospectively designed stability test protocols.



License Agreements



Genentech Inc.



The Company
holds a non-exclusive license from Genentech Inc. (“Genentech”) to certain patent rights to develop and sub-license a specified
polypeptide. In consideration of the license, the Company paid an upfront amount and could be required to pay to Genentech
additional milestones and royalties on sales. The initial amount paid upfront was a one-time non-creditable, non-refundable
fee which was immaterial to the Company. The aggregate milestone amounts payable under the agreement total $2,325,000.
Additionally, the Company is obligated to make royalty payments after the first commercial sale of the polypeptide within a
range of 1% to 5% on a country by country basis on an aggregate worldwide scale of net sales. No milestone or royalty
payments under this agreement have become due and the Company does not expect to make any milestone or royalty payments under
this agreement during the fiscal year ending May 31, 2014. The Company cannot reasonably predict when such royalties will
become payable, if at all. The agreement will terminate upon the expiration of the last patent, which is expected to be in
2020. The agreement may be terminated (i) by the Company for any reason upon 60 days prior written notice to Genentech or
(ii) by Genentech for any material breach of the agreement by the Company, provided that the Company has the option to cure
such breach within 30 days following written notice by Genentech.



18







Collaboration Agreements



Elanco



In April
2013, Lorus entered into a research and license option agreement with Elanco, the animal health division of Eli Lilly and
Company, to investigate a new proprietary series of Lorus’ compounds for veterinary medicine. Pursuant to the
agreement, Elanco agreed to fund the research program and was granted an exclusive option to license from Lorus our worldwide
rights for selected compounds for veterinary use; the terms of which will be negotiated if the option is exercised by Elanco.
Lorus retains the rights to develop and commercialize these compounds for human use and intends to use the animal data from
the collaboration as a basis for a partnership with a third party to develop the technology for the treatment
of patients with cancer. Lead optimization is underway and the next goal is to identify a clinical drug candidate that can
be developed for both human and animal use.



Cancer
Research UK



In November 2012,
Lorus entered into a clinical trial and option agreement with Cancer Research UK to develop IL-17E through to a Phase
I clinical trial. IL-17E (also known as IL-25) is a cytokine that plays an important role in inflammation. Lorus scientists were
the first to discover the anticancer properties of IL-17E against a range of solid tumors, including human melanoma, pancreatic,
colon, lung, ovarian and breast tumor models, with very low toxicity. Cancer Research UK, through its Clinical Development Partnerships
program, had agreed to fund and complete the preclinical studies, non-clinical toxicology studies and a Phase I clinical study
in solid tumors. This agreement was terminated by Cancer Research UK in early 2014.



Other



From time to time,
we enter into other research and technology agreements with third parties under which research is conducted and monies expended.
These agreements outline the responsibilities of each participant and the appropriate arrangements in the event the research produces
a product candidate.



Business Strategy



Our business strategy
is based on the identification and development of novel therapies that are effective, with fewer side effects than currently available
therapies. In order to minimize single technology-related risks, we have adopted the following technology approaches:



| | · | Development
                                         of small molecules that recognize specific targets in cancer cells;
| | - | ------------------------------------------------------------------------------------------------------------------------



| | · | Immunotherapy
                                         using safe and efficacious products to stimulate the natural anticancer properties of
                                         the immune system.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



In our efforts to
obtain the greatest return on our investment in each drug candidate, we separately evaluate the merits of each drug candidate
throughout the pre-clinical and clinical development process and consider commercialization opportunities when appropriate.



Our business model
is to take our product candidates through pre-clinical testing and into Phase I and Phase II clinical trials. It is our intention
to then partner or co-develop these drug candidates after successful completion of Phase I or II clinical trials. Lorus will give
careful consideration in the selection of partners that can best advance its drug candidates into a pivotal Phase III clinical
trial and, upon successful results, commercialization. Our objective is to receive upfront and milestone payments as well as royalties
from such partnerships, which will support continued development of our other product candidates.



Financial Strategy



To meet future financing
requirements, we intend to finance our operations through some or all of the following methods: public or private equity financings,
and collaborative and licensing agreements. We intend to pursue financing opportunities as they arise.



April 2014 Public Offering



Subsequent to the
fiscal year ended May 31, 2013, in April 2014 the Company completed a public offering of Common Shares. The Company issued a total
of 56,500,000 Common Shares at a purchase price of $0.50 per Common Share, including 6,500,000 Common Shares sold pursuant to
the partial exercise of an over-allotment option, for aggregate gross proceeds of $28,500,000.



19







December 2013 Public Offering and
Over Allotment



Subsequent
to the fiscal year ended May 31, 2013, on December 10, 2013 the Company completed a public offering of Common Shares.
The Company issued a total of 12,730,000 Common Shares at a price of $0.55 per Common Share, for aggregate gross proceeds
of $7,001,500. A related party of the Company by virtue of exercising control or direction over more than 10% of the then
outstanding Common Shares of the Company participated in the Offering and acquired an aggregate of 1,820,000Common
Shares.



In January
2014, the underwriters for our December 2013 public offering exercised in full their over-allotment option to purchase an
additional 1,909,500 Common Shares, at a purchase price of $0.55 per Common Share. As a result of the exercise of this
over-allotment option, Lorus received additional gross proceeds of $1,050,225 and raised total gross proceeds of $8,051,725
from the public offering.



September 2013 Private Placements



Subsequent to our
fiscal year ended May 31, 2013, in September 2013 the Company completed a private placement of convertible promissory notes for
aggregate gross proceeds of $600,000.



Each convertible promissory
note consists of a $1,000 principal amount of unsecured promissory note convertible into Common Shares at a purchase
price per share of $0.30. The promissory notes bear interest at a rate of 10% per annum, payable quarterly and are due September
26, 2015.



Also in September
2013, the Company received unsecured non-convertible loans in the aggregate principal amount of $150,000. The loans were
unsecured, bore interest at a rate of 10% per annum payable quarterly and had a maturity date of September 30, 2015.
The notes and all accrued and unpaid interest thereon were repaid on April 25, 2014.



June 2013 Private Placement



Subsequent to
our fiscal year ended May 31, 2013, in June 2013, Lorus completed a private placement of units consisting of (i) a $1,000
principal amount of unsecured promissory notes; and (ii) 1,000 Common Share purchase warrants at a price of $1,000 per unit,
for aggregate gross proceeds of $893,000. In July 2013, an additional $25,000 of unsecured promissory notes were issued in
the private placement for total gross proceeds of $918,000.



The
promissory notes bore interest at a rate of 10% per annum, payable monthly, and had a maturity date of June 19, 2014. Each
warrant entitled the holder thereof to acquire one Common Share at a price per Common Share equal to $0.25, at
any time through June 19, 2015. The maximum number of Common Shares issuable in connection with the private placement,
assuming the exercise of all warrants, is 918,000 Common Shares.



The promissory notes and all
accrued and unpaid interest thereon were repaid on April 22, 2014.



June 2012 Private Placement



On June 8, 2012, we
completed a private placement of 20,625,000 units at a subscription price of $0.32 per unit. Each unit consisted of one Common
Share and one Common Share purchase warrant for aggregate gross proceeds to Lorus of $6,600,000.



Each warrant is exercisable
for a period of 24 months from the date of issuance at an exercise price of $0.45 per share. If after one year the closing price
of the Common Shares on the TSX equals or exceeds $0.90 for twenty consecutive days, then we may send the warrant holders written
notice and issue a news release announcing an accelerated exercise date and then the warrants shall only be exercisable for a
period of 30 days following receipt of the notice, after which time they terminate if not exercised.



20







In
connection with the 2012 financing, we paid a cash finder’s fee of $396,000, based on 6% of the gross proceeds received
by Lorus from the private placement, and issued 1,237,500 finder’s warrants at an exercise price of $0.32 per
unit. Each finder’s warrant is exercisable for units consisting of 1,237,500 Common Shares and 1,237,500 Common
Share warrants.



August 2011 Unit Offering



On August
15, 2011, we closed a public offering for gross proceeds of $2,200,000, whereby we issued 5,500,000 Common Shares and
5,700,000 warrants, including aggregate broker warrants. Each warrant entitles the holder to purchase one Common Share for
five years after the closing of the offering at an exercise price of $0.45 per share. However, if on any date the 10-day volume
weighted average trading price of the Common Shares on the TSX equals or exceeds 200% of the $0.45 per share exercise price,
then Lorus can send the holders of warrants a written notice and issue a news release announcing the acceleration of the
exercise date, following which the warrants shall only be exercisable for a period of 30 days following the date of notice,
after which time the warrants will terminate if not exercised.



In
connection with the offering, Mr. Abramson, one of our directors at that time, entered into an irrevocable commitment letter
on June 20, 2011, as amended July 11, 2011, to purchase, directly or indirectly, Common Shares and Common Share purchase
warrants of Lorus having an aggregate subscription price equal to the difference if any, between (a) the sum of (i) the gross
proceeds realized by us in the offering and (ii) the gross proceeds received by us in respect of all financings completed by
us from the date of the final short-form prospectus to November 30, 2011, and (b) $4,000,000. Mr. Abramson purchased
2,400,000 units as part of the offering.



Promissory Notes Payable



Promissory notes
were issued subsequent to our fiscal year ended May 31, 2013 as described above under ‘June 2013 Private
Placement’.



Pursuant to the
commitment letter (described above under ‘August 2011 Unit Offering’) provided by Mr. Abramson, in November 2011,
we issued a grid promissory note to Mr. Abramson that allowed us to borrow funds up to $1,800,000. The funds could be
borrowed at a rate of up to $300,000 per month, incurred interest at a rate of 10% per year and were due and payable in full
on November 28, 2012. At May 31, 2012, $900,000 had been drawn under the promissory note and on June 27, 2012, the note and
all accrued interest there on were repaid.



Deferred
Share Unit Plan



As of May 31, 2013,
780,000 deferred share units had been issued under the deferred share unit plan of the Corporation (the“DSU Plan”),
780,000 as of May 31, 2012, with a carrying amount of $172,000 representing the fair market value of the units as of May 31,
2013 (May 31, 2012 - $304,000) recorded in accrued liabilities.



Warrant
Repricing



On November 29,
2011, shareholders of the Company (excluding insiders who also held warrants) approved a resolution to amend the exercise
price of Common Shares issuable pursuant to certain outstanding warrants, from $1.33 per share to the five-day volume
weighted average trading price on the TSX for the five days prior to approval plus a 10% premium. The revised exercise price
is $0.28 per share. The Company calculated an increased value attributed to the warrants of $239,000 related to the
amendment. This increase was calculated by taking the Black Scholes value of the warrants immediately before the amendment
and immediately after the amendment. There were 4,200,000 warrants which were amended and of those 3,600,000 were held by
Mr. Abramson, a director of the Company at that time.



Share
Consolidation



At our annual and
special meeting of shareholders held on November 30, 2009, our shareholders approved a special resolution permitting the Board,
in its sole discretion, to file an amendment to our articles of incorporation to consolidate our issued and outstanding Common
Shares. On May 12, 2010, the Board approved the share consolidation on the basis of one post-consolidation Common Share for every
30 pre-consolidation Common Shares. The record date and effective date for the share consolidation was May 25, 2010. Our Common
Shares began trading on the TSX on a post-consolidation basis on May 31, 2010. The share consolidation resulted in an adjustment
to the exercise price and number of Common Shares issuable upon exercise of outstanding stock options and warrants.



21







In this Annual Report,
all references to number of Common Shares, stock options and warrants in the current and past periods have been adjusted to reflect
the impact of the May 2010 consolidation unless noted otherwise.



Intellectual Property
and Protection of Confidential Information and Technology



We believe that our
issued patents and pending applications are important in establishing and maintaining a competitive position with respect to our
products and technology.



Small Molecule



As of April 30, 2014, we had 18issued patents and 10 pending patents worldwide for our in-house small molecules. These patents cover composition of matter
and method claims.



Immunotherapy



As of April 30, 2014
we had two issued patents and one pending patent for our IL-17E immunotherapy program.



Lorus has entered
into a licence agreement with Genentech which provides Lorus the right to use the IL-17E composition patent for cancer use, as
described above under License Agreements.



Other Therapies



As of April 30, 2014,
we had 13 issued patents and one pending patent worldwide for our DNA-based therapeutics. These patents include composition
of matter and method claims.



Risks Relating
to Intellectual Property



Pending applications
may not result in issued patents and issued patents may not be held valid and enforceable if challenged. Competitors may be able
to circumvent any such issued patents by adoption of a competitive, though non-infringing product or process. Interpretation and
evaluation of pharmaceutical or biotechnology patent claims present complex and often novel legal and factual questions. Our business
could be adversely affected by increased competition in the event that any patent granted to it is held to be invalid or unenforceable
or is inadequate in scope to protect our operations.



While we believe that
our products and technology do not infringe proprietary rights of others, third parties may assert infringement claims in the
future and such claims could be successful. Even if challenges are unsuccessful, we could incur substantial costs in defending
ourselves against patent infringement claims brought by others or in prosecuting suits against others. In addition, others may
obtain patents that we would need to license, which may not be available to us on reasonable terms. Whether we are able to obtain
a necessary license would depend on the terms offered, the degree of risk of infringement and the need for the patent.



Until such time, if
ever, that further patents are issued to us, we will rely upon the law of trade secrets to the extent possible given the publication
requirements under international patent treaty laws and/or requirements under foreign patent laws to protect our technology and
our products incorporating the technology. In this regard, we have adopted certain confidentiality procedures. These include:
limiting access to confidential information to certain key personnel; requiring all directors, officers, employees and consultants
and others who may have access to our intellectual property to enter into confidentiality agreements which prohibit the use of
or disclosure of confidential information to third parties; and implementing physical security measures designed to restrict access
to such confidential information and products. Our ability to maintain the confidentiality of our technology is crucial to our
ultimate possible commercial success. The procedures adopted by us to protect the confidentiality of our technology may not be
effective, third parties may gain access to our trade secrets or disclose our confidential technology. Further, by seeking patent
protection in various countries, it is inevitable that a substantial portion of our technology will become available to our competitors,
through publication of such patent applications.



22









Regulatory Strategy



Our overall regulatory
strategy is to work with the appropriate government departments which regulate the use and sale of therapeutic drug products.
This includes Health Canada in Canada, the Food and Drug Administration in the United States, the European Medicines Agency in
Europe, and other local regulatory agencies with oversight of preclinical studies, clinical trials and marketing of therapeutic
products. Where possible, we intend to take advantage of opportunities for accelerated development of drugs designed to treat
rare and serious or life-threatening diseases. We also intend to pursue priority evaluation of any application for marketing approval
filed in Canada, the United States or the European Union and to file additional drug applications in other markets where commercial
opportunities exist. We may not be able to pursue these opportunities successfully.



Revenues



The Company has not earned substantial
revenues from its drug candidates and is therefore considered to be in the development stage.



Employees



As of April 30, 2014,
we employed 19 full-time persons and three part-time people in research and drug development and administration activities. Among
our employees, five hold Ph.D.’s, five hold MSc degrees, one holds a DVM degree and numerous others hold degrees and
designations such as BSc, CPA (CA), CPA (California) and MBA. To encourage a focus on achieving long-term performance,
employees and members of the Board have the ability to acquire an ownership interest in the Company through Lorus’ share
option and alternate compensation plans. See Item 6.B – Compensation.



None of our employees
are unionized, and we consider our relations with our employees to be good.



Office Facilities



Our head office, which
occupies 20,500 square feet, is located at 2 Meridian Road, Toronto, Ontario. The leased premises include approximately 8,000
square feet of laboratory and research space. We believe that our existing facilities are adequate to meet our requirements for
the near term. Our current lease expires on March 31, 2015.



Subsequent to the
fiscal year end, we entered into a lease agreement for three offices in San Diego, California. This lease expires December 31,
2014.



Subsequent to the
fiscal year end, in February 2014, we entered into a lease agreement on a month to month basis for 188 square feet of office space
in Menlo Park, California, cancellable by either party upon 30 days prior notice.



Competition



The biotechnology
and pharmaceutical industries are characterized by rapidly evolving technology and intense competition. There are numerous companies
in these industries that are focusing their efforts on activities similar to ours. Some of these are companies with established
positions in the pharmaceutical industry and may have substantially more financial and technical resources, more extensive research
and development capabilities, and greater marketing, distribution, production and human resources than Lorus. In addition, we
face competition from other companies for opportunities to enter into partnerships with biotechnology and pharmaceutical companies
and academic institutions.



23







Competition with our
potential products may include chemotherapeutic agents, monoclonal antibodies, antisense therapies, small molecules, immunotherapies,
vaccines and other biologics with novel mechanisms of action. These drugs may kill cancer cells indiscriminately, or through a
targeted approach, and some have the potential to be used in non-cancer indications. We also expect that we will experience competition
from established and emerging pharmaceutical and biotechnology companies that have other forms of treatment for the cancers that
we target, including drugs currently in development for the treatment of cancer that employ a number of novel approaches for attacking
these cancer targets. Cancer is a complex disease with more than 100 indications requiring drugs for treatment. The drugs in competition
with our potential drugs have specific targets for attacking the disease, targets which are not necessarily the same as ours.
These competitive drugs, however, could potentially also be used together in combination therapies with our drugs to manage the
disease. Other factors that could render our potential products less competitive may include the stage of development, where competitors’
products may achieve earlier commercialization, as well as superior patent protection, better safety profiles, or a preferred
cost-benefit profile.



Government Regulation



Overview

Regulation by government
authorities in Canada, the United States, and the European Union is a significant factor in our current research and drug development
activities. To clinically test, manufacture and market drug products for therapeutic use, we must satisfy the rigorous mandatory
procedures and standards established by the regulatory agencies in the countries in which we currently operate or intend to operate.



The laws of most of
these countries require the licensing of manufacturing facilities, carefully controlled research and the extensive testing of
products. Biotechnology companies must establish the safety and efficacy of their new products in clinical trials; they must establish
current GMP(s) and control over marketing activities before being allowed to market a product. The safety and efficacy of a new
drug must be shown through human clinical trials of the drug carried out in accordance with the mandatory procedures and standards
established by regulatory agencies.



The process of completing
clinical trials and obtaining regulatory approval for a new drug takes a number of years and requires the expenditure of substantial
resources. Once a new drug or product license application is submitted, regulatory agencies may not review the application in
a timely manner and may not approve the product. Even after initial approval has been obtained, further studies, including post-marketing
studies, may be required to provide additional data on efficacy and safety necessary to confirm the approved indication or to
gain approval for the use of the new drug as a treatment for clinical indications other than those for which the new drug was
initially tested. Also, regulatory agencies require post-marketing surveillance programs to monitor a new drug’s side effects
and safety. Results of post-marketing programs may limit or expand the further marketing of new drugs. A serious safety or effectiveness
problem involving an approved new drug may result in a regulatory agency requiring withdrawal of the new drug from the market
and possible civil action. It is possible that we could encounter such difficulties or excessive costs in our efforts to secure
necessary approvals, which could delay or prevent us from manufacturing or marketing our products.



In addition to the
regulatory product approval framework, biotechnology companies, including Lorus, are subject to regulation under local, provincial,
state and federal law, including requirements regarding occupational safety, laboratory practices, environmental protection and
hazardous substance control, and may be subject to other present and future local, provincial, state, federal and foreign regulation,
including possible future regulation of the biotechnology industry.



Regulation
in Canada



In Canada, the manufacture
and sale of new drugs are controlled by Health Canada. New drugs must pass through a number of testing stages, including pre-clinical
testing and human clinical trials. Pre-clinical testing involves testing the new drug’s chemistry, pharmacology and toxicology
in vitro and in vivo. Successful results (that is, potentially valuable pharmacological activity combined with an
acceptable low level of toxicity) enable the developer of the new drug to file a clinical trial application to begin clinical
trials involving humans.



24







To study a drug in
Canadian patients, a clinical trial application submission must be filed with Health Canada. The clinical trial application submission
must contain specified information, including the results of the pre-clinical tests completed at the time of the submission and
any available information regarding use of the drug in humans. In addition, since the method of manufacture may affect the efficacy
and safety of a new drug, information on manufacturing methods and standards and the stability of the drug substance and dosage
form must be presented. Production methods and quality control procedures must be in place to ensure an acceptably pure product,
essentially free of contamination, and to ensure uniformity with respect to all quality aspects.



In addition, all federally
regulated trials must be approved and monitored by an independent committee of doctors, scientists, advocates and others to ensure
safety and ethical standards. These committees are called Institutional Review Boards (“IRBs”) or Ethics Review
Boards (“ERBs”). The review boards study and approve all study-related documents before a clinical trial begins
and also carefully monitor data to detect benefit or harm, and validity of results.



Provided Health Canada
does not reject a clinical trial application submission and IRB or ERB approval has been obtained, clinical trials can begin.
Clinical trials for product candidates in Canada, as in the U.S. generally are carried out in three phases. Phase I involves studies
to evaluate toxicity and ideal dose levels in healthy humans. The new drug is administered to human patients who have met the
clinical trial entry criteria to determine pharmacokinetics, human tolerance and prevalence of any adverse side effects. Phases
II and III involve therapeutic studies. In Phase II, efficacy, dosage, side effects and safety are established in a small number
of patients who have the disease or disorder that the new drug is intended to treat. In Phase III, there are controlled clinical
trials in which the new drug is administered to a large number of patients who are likely to receive benefit from the new drug.
In Phase III, the effectiveness of the new drug in patients is compared to that of standard accepted methods of treatment in order
to provide sufficient data for the statistical proof of safety and efficacy for the new drug.



If clinical studies
establish that a new drug has value, the manufacturer submits a new drug submission application to Health Canada for marketing
approval. The new drug submission contains all information known about the new drug, including the results of pre-clinical testing
and clinical trials. Information about a substance contained in new drug submission includes its proper name, its chemical name,
and details on its method of manufacturing and purification, and its biological, pharmacological and toxicological properties.
The new drug submission also provides information about the dosage form of the new drug, including a quantitative listing of all
ingredients used in its formulation, its method of manufacture, manufacturing facility information, packaging and labelling, the
results of stability tests, and its diagnostic or therapeutic claims and side effects, as well as details of the clinical trials
to support the safety and efficacy of the new drug. Furthermore, for biological products, an on-site evaluation is completed to
assess the production process and manufacturing facility. It is required prior to the issuance of a notice of compliance. All
aspects of the new drug submission are critically reviewed by Health Canada. If a new drug submission is found satisfactory, a
notice of compliance is issued permitting the new drug to be sold for the approved use. In Canada, an establishment license must
be obtained prior to marketing the product.



Health Canada has
a policy of priority evaluation of new drug submissions for all drugs intended for serious or life-threatening diseases for which
no drug product has received regulatory approval in Canada and for which there is reasonable scientific evidence to indicate that
the proposed new drug is safe and may provide effective treatment.



The monitoring of
a new drug does not cease once it is on the market. For example, a manufacturer of a new drug must report any new information
received concerning serious side effects, as well as the failure of the new drug to produce desired effects. If Health Canada
determines it to be in the interest of public health, a notice of compliance for a new drug may be suspended and the new drug
may be removed from the market.



A post surveillance
program involves clinical trials conducted after a drug is marketed (referred to as Phase IV studies in the United States) and
is an important source of information on as yet undetected adverse outcomes, especially in populations that may not have been
involved in the premarketing trials (e.g., children, the elderly, pregnant women) and the drug’s long-term morbidity and
mortality profile. Regulatory authorities may require companies to conduct Phase IV studies as a condition of market approval.
Companies often conduct post-marketing studies in the absence of a regulatory mandate.



25







An exception to the
foregoing requirements relating to the manufacture and sale of a new drug is the limited authorization that may be available in
respect of the sale of new drugs for emergency treatment. Under the special access program, Health Canada may authorize the sale
of a quantity of a new drug for human use to a specific practitioner for the emergency treatment of a patient under the practitioner’s
care. Prior to authorization, the practitioner must supply Health Canada with information concerning the medical emergency for
which the new drug is required, such data as is in the possession of the practitioner with respect to the use, safety and efficacy
of the new drug, the names of the institutions at which the new drug is to be used and such other information as may be requested
by Health Canada. In addition, the practitioner must agree to report to both the drug manufacturer and Health Canada the results
of the new drug’s use in the medical emergency, including information concerning adverse reactions, and must account to
Health Canada for all quantities of the new drug made available.



The Canadian regulatory
approval requirements for new drugs outlined above are similar to those of other major pharmaceutical markets. While the testing
carried out in Canada is often acceptable for the purposes of regulatory submissions in other countries, individual regulatory
authorities may request supplementary testing during their assessment of any submission. Therefore, the clinical testing conducted
under Health Canada authorization or the approval of regulatory authorities of other countries may not be accepted by regulatory
authorities outside Canada or other countries.



Regulation
in the United States



In the United States,
the FDA controls the manufacture and sale of new drugs. New drugs require FDA approval of a New Drug Application prior to commercial
sale. In the case of certain biological products, a Biological License Application must be obtained prior to marketing and batch
releasing. As in Canada, to obtain marketing approval, data from adequate and well-controlled human clinical trials, demonstrating
to the FDA’s satisfaction a new drug’s safety and effectiveness for its intended use, are required. Data are generated
in studies conducted pursuant to an IND submission, similar to that required for a clinical trial application in Canada. As in
Canada, clinical studies are characterized as Phase I, Phase II and Phase III trials or a combination thereof. In a marketing
application, the manufacturer must also demonstrate the identity, potency, quality and purity of the active ingredients of the
new drug involved, and the stability of those ingredients. Further, the manufacturing facilities, equipment, processes and quality
controls for the new drug must comply with the FDA’s current Good Manufacturing Practice regulations for drugs or biological
products both in a pre-licensing inspection before product licensing and in subsequent periodic inspections after licensing. An
establishment license grants the sponsor permission to fabricate, package, label, distribute, import, wholesale or test of the
newly approved drug.



The above describes
briefly what is necessary for a new drug to be approved for marketing in North America. The European Medicines Agency and Japanese
Pharmaceuticals and Medical Devices Agency are also important regulatory authorities in drug development. Together with the FDA,
they are the three International Conference on Harmonization parties which oversee the three largest markets for drug sales.



C.           Organizational
structure.



Old Lorus was incorporated
under the Business Corporations Act(Ontario) on September 5, 1986 under the name RML Medical Laboratories Inc. On October
28, 1991, RML Medical Laboratories Inc. amalgamated with Mint Gold Resources Ltd., resulting in Old Lorus becoming a reporting
issuer (as defined under Canadian securities law) in Ontario, on such date. On August 25, 1992, Old Lorus changed its name to
IMUTEC Corporation. On November 27, 1996, Old Lorus changed its name to Imutec Pharma Inc., and on November 19, 1998, Old Lorus
changed its name to Lorus Therapeutics Inc. On October 1, 2005, Old Lorus continued under the Canada Business Corporations
Act. On July 10, 2007, the Old Lorus changed its name from Lorus Therapeutics Inc. to 4325231 Canada Inc. and on October 17,
2007 changed its name to Global Summit Real Estate Inc. As of the Arrangement Date, Old Lorus is not related to New Lorus.



New Lorus was incorporated
on November 1, 2006 as 6650309 Canada Inc. under the Canada Business Corporations Act.



On July 10, 2007 (the
“Arrangement Date”), Old Lorus completed a plan of arrangement and corporate reorganization with, among others,
6650309 Canada Inc., subsequently renamed Lorus Therapeutics Inc. (New Lorus), 6707157 Canada Inc. and Pinnacle International
Lands, Inc. As a result of the plan of arrangement and reorganization, among other things, each common share of Old Lorus was
exchanged for one Common Share of New Lorus and the assets (excluding certain future tax attributes and related valuation allowance)
and liabilities of Old Lorus (including all of the shares of its subsidiaries held by it) were transferred, directly or indirectly,
to the Company and/or its subsidiaries. New Lorus continued the business of Old Lorus after the Arrangement Date with the same
officers and employees and continued to be governed by the same directors as Old Lorus prior to the Arrangement Date. At the Arrangement
Date, New Lorus’ articles of incorporation were amended to change the name of the Company from 6650309 Canada Inc. to Lorus
Therapeutics Inc.



26







Lorus currently has
one subsidiary, NuChem, of which Lorus owns 80% of the issued and outstanding voting share capital and 100% of the issued and
outstanding non-voting preference share capital.



Lorus’ Common
Shares are listed on the TSX under the symbol “LOR”.



The address of the
Company’s head and registered office is 2 Meridian Road, Toronto, Ontario, Canada, M9W 4Z7, and our phone number is (416)
798-1200. Our corporate website is www.lorusthera.com. The contents of the website, and items accessible through the website,
are specifically not incorporated in this Annual Report by reference.



D.           Property,
plants and equipment.



Our head office, which
occupies 20,500 square feet, is located at 2 Meridian Road, Toronto, Ontario. The leased premises include approximately 8,000
square feet of laboratory and research space. We believe that our existing facilities are adequate to meet our requirements for
the near term. Our current lease expires on March 31, 2015.



Subsequent to the
fiscal year end, in January 2014, we entered into a lease agreement for three offices in San Diego, California. This lease expires
December 31, 2014.



Subsequent to the
fiscal year end, in February 2014, we entered into a lease agreement on a month to month basis for 188 square feet of office space
in Menlo Park, California.



Item 4A.           Unresolved
Staff Comments



Not applicable.



Item
5.              Operating and Financial Review and
Prospects



A.           Operating
results.



Please see our Management
Discussion and Analysis for the year ended May 31, 2013 in Exhibit 15.1, which is incorporated herein by reference.



B.            Liquidity and capital resources.



Please see our Management
Discussion and Analysis for the year ended May 31, 2013 in Exhibit 15.1, which is incorporated herein by reference.



C.           Research
and development, patents and licenses, etc.



Certain information
concerning research and development and intellectual property is set forth in Item 4, “Information on the Company”.



D.           Trend
information.



We have a history
of operating losses and have not been profitable since our inception in 1986. We expect to continue to incur losses for at least
the next several years as we and our collaborators and licensees pursue clinical trials and research and development efforts.
See “Risk Factors” above.



27







E.           Off-balance
sheet arrangements.



As at May 31, 2013, we have not entered
into any off-balance sheet arrangements.



F.           Tabular
disclosure of contractual obligations.



|(In thousands)              |  | Payments due by period |    
|--------------------------- |  | ---------------------- | ---
|Contractual Obligations     |  | Total                  |    
|Operating lease obligations |  | $                      | 289



The Company’s
current facility lease expires in March 2015.



We hold a non-exclusive
license from Genentech Inc. to certain patent rights to develop and sub-license a certain polypeptide. We do not expect to make
any milestone or royalty payments under this agreement in the fiscal year ending May 31, 2014, and cannot reasonably predict when
such milestones and royalties will become payable, if at all.



We entered into various
contracts with service providers with respect to the LOR-253 Phase I clinical trial. These contracts could result in future payment
commitments by Lorus of approximately $1.5 million. Of this amount, $740,000 has been paid and $253,000was accrued at
May 31, 2013 (2012 $439,000 paid and $70,000 accrued). The payments will be based on services performed and amounts may be higher
or lower based on actual services performed.



On November 27, 2012,
we entered into a collaboration agreement with Cancer Research UK for the future development of our immunotherapy IL-17E. Under
this collaboration agreement we were committed to provide sufficient quantity of the drug IL-17E, for no cash consideration, to
be used by Cancer Research UK in pre-clinical toxicology studies and, should those studies be successful, a Phase I clinical trial.
This collaboration was terminated by Cancer Research UK in early 2014. The Company no longer has an obligation to provide
IL-17E to Cancer Research UK.



On July 10, 2007,
we completed a plan of arrangement and corporate reorganization with Old Lorus. As part of the arrangement, we agreed to indemnify
Old Lorus and its directors, officers and employees from and against all damages, losses, expenses (including fines and penalties),
other third party costs and legal expenses, to which any of them may be subject arising out of the arrangement. We recorded a
liability of $75,000, which we believe to be a reasonable estimate of the fair value of the obligation for the indemnifications
provided as at May 31, 2013. There have been no claims on this indemnification to date.



Item 6.          Directors,
Senior Management and Employees



A.           Directors
and senior management.



The following table
and notes thereto provide the name, province or state and country of residence, positions with the Company and term of office
of each person who serves as a director or executive officer of Lorus as at the date hereof.



Each director has
been elected or appointed to serve until the next annual meeting or until a successor is elected or appointed. We have an Audit
Committee, a Corporate Governance and Nominating Committee and a Compensation Committee, the members of each such committee are
shown below. As April 30, 2014, our directors and executive officers, as a group, beneficially owned, directly or indirectly,
or exercised control over approximately 3,091,220 of our Common Shares or approximately 2.5% of our outstanding Common Shares.



28







|Name and Province/State and 
Country of Residence                                |  | Position                                          |  | Director or Officer Since
|-------------------------------------------------------------------------------- |  | ------------------------------------------------- |  | -------------------------
|Denis Burger,
        Ph.D.(1)(2) Oregon, United States
        
        Age: 70 |  | Director                                          |  | September 2007           
|                                                                                 |  |                                                   |  |                          
|Bradley Thompson,
        Ph.D.(3)
        Alberta, Canada
        Age: 57       |  | Director                                          |  | June 2013                
|                                                                                 |  |                                                   |  |                          
|Brian Underdown, Ph.D.(1)                                                        |  | Director                                          |  | December 2013            
|Ontario, Canada
        Age: 73                                                  |  |                                                   |  |                          
|                                                                                 |  |                                                   |  |                          
|Mark Vincent,
        MD(3)
        Ontario, Canada
        Age: 61              |  | Director                                          |  | September 2007           
|                                                                                 |  |                                                   |  |                          
|Warren Whitehead(1)
        Ontario, Canada
        Age: 62                      |  | Director                                          |  | April 2011               
|                                                                                 |  |                                                   |  |                          
|Jim A. Wright,
        Ph.D.(2)
Ontario, Canada
        Age: 71                  |  | Lead Director                                     |  | October 1999             
|                                                                                 |  |                                                   |  |                          
|William G. Rice,
        Ph.D.
        California, United States
        Age: 55 |  | Chairman, President and Chief Executive Officer   |  | October 2013             
|                                                                                 |  |                                                   |  |                          
|Gregory Chow
California, United States
        Age: 41                           |  | Senior Vice President and Chief Financial Officer |  | November 2013            
|                                                                                 |  |                                                   |  |                          
|Avanish Vellanki
        California, United States
        Age: 39               |  | Senior Vice President and Chief Business Officer  |  | November 2013            



(1)         Member
of the Audit Committee.
(2)         Member of the Compensation Committee.
(3)         Member of the Corporate Governance and Nominating Committee.

29







The principal occupation and employment
of each of the foregoing persons for the past five years is set forth below:



Dr. Denis
Burger:Dr. Burger currently is the Chairman of AMES Devices, a medical device company. Dr. Burger co-founded Trinity
Biotech plc, based in Dublin, Ireland, in June 1992 and acted as Chairman from 1992 to 1995 and now serves on the Board of Directors
of the Company.  Dr. Burger was the past Chairman, Chief Executive Officer and a director of AVI Biopharma Inc., an Oregon
based biotechnology company, from 1992 to March 2007. Dr. Burger is also a partner in Sovereign Ventures, a healthcare consulting
and funding firm based in Portland, Oregon. Dr. Burger received his MSc and Ph.D. in Microbiology and Immunology from the
University of Arizona. Dr. Burger also serves on the Board of Biocurex Inc.



Dr. William Rice:Dr. Rice joined Lorus as Chairman and Chief Executive Officer in October 2013.Prior to joining Lorus, Dr. Rice served
as the President, Chief Executive Officer and Chairman of the Board of Cylene Pharmaceuticals, Inc., a private biotechnology
company (“Cylene”). Prior to Cylene, Dr. Rice was the founder, President, Chief Executive Officer and Director of
Achillion Pharmaceuticals, Inc. He also served as Senior Scientist and Head of the Drug Mechanism Laboratory at the National Cancer
Institute-Frederick Cancer Research and Development Center, and served as a faculty member in the division of Pediatric Hematology
and Oncology at Emory University School of Medicine.  Dr. Rice also serves on the Board of Cylene.



Dr. Brad Thompson:Dr. Thompson is an experienced biotechnology professional who has held the positions of Chairman of the Board and President
and Chief Executive Officer of Oncolytics Biotech Inc. since April 1999. Prior to his role with Oncolytics Dr. Thompson was the
Chief Executive Officer of Synsorb Biotech from 1994 to 1999. Dr. Thompson also currently is a board member of Immunovaccine Inc.
He received his Ph.D. from the University of Western Ontario in the Department of Microbiology and Immunology.



Dr. Brian Underdown:Dr. Underdown is a Managing Director of Lumira Capital, Investment Management, one of Canada’s leading venture capital
firms with offices in Canada and the United States.   Since joining Lumira and its preceding company, MDS Capital, in
1997, Dr. Underdown has focused on investments in North American therapeutics companies at all stages of development. With over
15 years of investment and operational experience in the biopharmaceutical sector, he has been a key player in the growth of over
10 life science companies in Canada and the U.S. Dr. Underdown also serves as a director of VistaGen Therapeutics Inc. and Argos
Therapeutics Inc.



Dr. Mark Vincent:Dr. Mark Vincent is a Professor of Oncology at the University of Western Ontario and a staff medical oncologist at the
London Regional Cancer Program, where he has been since 1990. Dr. Vincent is also the co-founder and Chief Executive Officer
of Sarissa, Inc. since 2000.



Dr.
Jim Wright: Dr. Wright is presently Chief Executive Officer of NuQuest Bio Inc., a position he has held since 2006.
As of July 1, 2010, Dr. Wright accepted a position as an Adjunct Professor in the Department of Biochemistry and
Biomedical sciences at McMaster University. Dr. Wright co-founded GeneSense Technologies Inc. in 1996, which merged with
Lorus in October 1999, and previously served as Lorus' President and Chief Executive Officer  from
October 1999 to September
2006.Dr. Wright was a Professor in the Faculties of Science and Medicine at the University of Manitoba, Senior
Scientist and Associate Director of the Manitoba Institute of Cell Biology, and Terry Fox Senior Scientist of the National
Cancer Institute prior to 1996.



Mr. Warren Whitehead:Mr. Whitehead is a Certified Management Accountant who has held senior financial management positions in several biotechnology
and pharmaceutical companies. Currently he is the Chief Financial Officer of Amorfix Life Sciences Ltd. Prior to this, he served
as Chief Financial Officer of ARIUS Research Inc., providing financial guidance and leadership during the acquisition of ARIUS
by Roche in 2008.  Prior to ARIUS, Mr. Whitehead was Chief Financial Officer at Labopharm Inc., where he completed a series
of public equity financings and a listing on NASDAQ.   He is currently a member of the Board of Directors of PlantForm
Corporation, a life sciences company that develops biosimilar antibody drugs for treatment of cancer and other critical illnesses.



Gregory Chow:
Mr. Chow joined Lorus as Chief Financial Officer in December 2013. Previously, Mr. Chow served as Managing Director, Director
of Private Placements at Wedbush Securities, where he led the private placement capital activities within the Life Sciences Investment
Banking Group. Prior to joining Wedbush, he was a Director in the Private Placements / Equity Capital Markets Group at RBC
Capital Markets, where he led life science private capital activities. Previously, he led the Private Capital Group at Wells Fargo
Securities and was a Senior Auditor at BDO Seidman, LLP in their Century City, CA office.  Mr. Chow is a Certified Public
Accountant (inactive) in the State of California.



30







Avanish Vellanki:Mr. Vellanki became Lorus’ Chief Business Officer in December 2013,having mostrecently served as Senior Vice
President, Investment Banking at Wedbush Securities focusing on the biotechnology sector.  Prior to Wedbush Securities, Mr.
Vellanki held the position of Senior Director of Corporate Development at Proteolix, Inc. (acquired by Onyx Pharmaceuticals),
a biotechnology company focused on the development of oncology therapeutics. Previously, Mr. Vellanki served as Vice President
in the Global Healthcare Investment Banking team at Citigroup’s Global Healthcare Investment Banking, where he focused on
large cap global biopharma strategic and financial advisory.  Mr. Vellanki began his career at Bear Stearns as an equity
research analyst covering the small/mid-cap biotechnology sector, and held the title of Vice President as a publishing analyst.



There are no family
relationships among the persons named above and there are no arrangements or understanding with major shareholders, customers,
suppliers or others pursuant to which any person was selected as a director or member of senior management.



B.           Compensation.



Summary of Executive Compensation



The following table
details the compensation information for the last three fiscal years of the Corporation, for the President and Chief Executive
Officer, the Director of Finance and Acting Chief Financial Officer and the Vice President of Research (“Named Executive
Officers”).The figures are in Canadian dollars.



Summary Compensation Table

|                                  |  | Non-equity
    incentive plan compensation |     
|--------------------------------- |  | ------------------------------------------ | ----
|Name and
    Principal Position   |  | Fiscal
    Year 
ended 
May 31             |     
|Dr. Aiping Young(3)               |  |                                            | 2013
|President and Chief               |  |                                            | 2012
|Executive Officer                 |  |                                            | 2011
|                                  |  |                                            |     
|Ms. Elizabeth Williams            |  |                                            | 2013
|Director of Finance, Acting Chief |  |                                            | 2012
|Financial Officer(4)              |  |                                            | 2011
|                                  |  |                                            |     
|Dr. Yoon Lee                      |  |                                            | 2013
|Vice President Research           |  |                                            | 2012
|                                  |  |                                            | 2011



| | (1) | During the year ended May 31, 2012, 780,000 deferred
share units were issued to Dr. Aiping Young. The deferred share units are measured at fair value and during the fiscal year ended
May 31, 2013, the fair value had decreased from $304,200 at May 31, 2012 to $171,600, resulting in a reduction in value of $132,600.
Dr. Aiping Young departed from the Corporation on March 18, 2014. For a description of our Deferred Common Share Units Plan, see
below. In April 2014, the Deferred Share Units held by Dr. Young were settled through the issuance of an equivalent number of Common
Shares.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | In determining the fair value of these option-based awards for the purchase of our Common
                                                                                Shares, the Black-Scholes valuation methodology was used with the following assumptions: (i) expected life of five
                                                                                years; (ii) volatility of 135%; (iii) risk free interest rate of 3%; and (iv) no dividend yield.The Corporation uses
                                                                                the Black-Scholes valuation methodology because it is equivalent to the option value reported in the
                                                                                Corporation’s consolidated financial statements. All options were granted at an exercise price equal to fair market
                                                                                value                                                                                 on the
                                                                                date                                                                                                                 of grant
                                                                                at                                                                                 exercise prices ranging from
                                                                                $0.18 to                                                                                    $1.05 per share. In accordance
                                                                                with the terms of the Share Option Plan (described
                                                                                below), all options typically expire on the earlier of ten years from the date of grant or within three months of
                                                                                termination.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



31







| | (3) | Dr. Aiping Young was named Chief Operating Officer on
October 28, 2013. On this date, she was replaced as Chief Executive Officer by William G. Rice, Ph.D. Dr. Young left the Company
on March 18, 2014.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (4) | Gregory Chow was appointed as our Chief Financial Officer
on December 2, 2013.
| | --- | ------------------------------------------------------------------------------



|Name and Principal 
    Position |  | Fiscal Year |  | Salary |         |  | Cash Bonus(1) |  |         | Other Annual Compensation |  | Securities Under Options/SARs
    Granted |  |  | All Other Compensation | 
|-------------------------------- |  | ----------- |  | ------ | ------- |  | ------------- |  | ------- | ------------------------- |  | ----------------------------------------- |  |  | ---------------------- | 
|                                 |  |             |  | ($)    |         |  | ($)           |  |         | ($)                       |  | (#)(2)                                    |  |  | ($)                    | 
|                                 |  |             |  |        |         |  |               |  |         |                           |  |                                           |  |  |                        | 
|Dr. Aiping
    Young(3)          |  | 2013        |  |        | 352,937 |  |               |  | 128,416 |                           |  | Nil                                       |  |  | 1,060,000              | 
|President and Chief              |  | 2012        |  |        | 349,334 |  |               |  | Nil     |                           |  | Nil                                       |  |  | 275,000                | 
|Executive Officer                |  | 2011        |  |        | 342,819 |  |               |  | 127,845 |                           |  | Nil                                       |  |  | 784,400                | 
|                                 |  |             |  |        |         |  |               |  |         |                           |  |                                           |  |  |                        | 
|Ms. Elizabeth Williams           |  | 2013        |  |        | 69,659  |  |               |  | 9,535   |                           |  | Nil                                       |  |  | 100,000                | 
|Director of Finance, Acting      |  | 2012        |  |        | 68,923  |  |               |  | Nil     |                           |  | Nil                                       |  |  | 162,000                | 
|Chief Financial Officer(4)       |  | 2011        |  |        | 66,322  |  |               |  | 808     |                           |  | Nil                                       |  |  | 62,015                 | 
|                                 |  |             |  |        |         |  |               |  |         |                           |  |                                           |  |  |                        | 
|Dr. Yoon Lee                     |  | 2013        |  |        | 139,546 |  |               |  | 26,484  |                           |  | Nil                                       |  |  | 150,000                | 
|Vice President Research          |  | 2012        |  |        | 138,071 |  |               |  | Nil     |                           |  | Nil                                       |  |  | 167,000                | 
|                                 |  | 2011        |  |        | 135,405 |  |               |  | 25,599  |                           |  | Nil                                       |  |  | 66,725                 | 



| | (1) | Cash bonuses are assessed by the Compensation Committee
and approved by the Board based on corporate objectives. Bonuses for the year ended May 31, 2013 were paid in the year ended May
31, 2014.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | Number of stock options granted during fiscal 2013. These
options were granted on August 2, 2013 at a price of $0.475 and have a ten-year life.
| | --- | -----------------------------------------------------------------------------------------------------------------------------------------------



| | (3) | Dr. Aiping Young was named Chief Operating Officer on
October 28, 2013. On this date, she was replaced as Chief Executive Officer by William G. Rice, Ph.D. Dr. Young left the Company
on March 18, 2014.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (4) | Gregory Chow was appointed as our Chief Financial Officer
on December 2, 2013.
| | --- | ------------------------------------------------------------------------------



Directors’ Compensation



The following table
details the compensation received by each director for the fiscal year ended May 31, 2013:



32







|Name                     |  | Fees
    earned ($) |        |  | Share-based
    awards ($) |     | Option- based awards ($)(1) |  |        | Non-equity
    incentive plan compensation ($) |  | Pension
    value ($) |  | All
    other Compensation ($) |  | Total
    ($) | 
|------------------------ |  | ------------------- | ------ |  | -------------------------- | --- | --------------------------- |  | ------ | ---------------------------------------------- |  | --------------------- |  | ------------------------------ |  | ------------- | 
|                         |  |                     |        |  |                            |     |                             |  |        |                                                |  |                       |  |                                |  |               | 
|Mr. Herbert Abramson (2) |  |                     | 34,500 |  |                            | Nil |                             |  | 6,330  |                                                |  | Nil                   |  | N/A                            |  | Nil           | 
|                         |  |                     |        |  |                            |     |                             |  |        |                                                |  |                       |  |                                |  |               | 
|Dr. Denis Burger         |  |                     | 34,500 |  |                            | Nil |                             |  | 6,330  |                                                |  | Nil                   |  | N/A                            |  | Nil           | 
|                         |  |                     |        |  |                            |     |                             |  |        |                                                |  |                       |  |                                |  |               | 
|Dr. Mark Vincent         |  |                     | 25,500 |  |                            | Nil |                             |  | 6,330  |                                                |  | Nil                   |  | N/A                            |  | Nil           | 
|                         |  |                     |        |  |                            |     |                             |  |        |                                                |  |                       |  |                                |  |               | 
|Mr. Warren Whitehead     |  |                     | 31,500 |  |                            | Nil |                             |  | 6,330  |                                                |  | Nil                   |  | N/A                            |  | Nil           | 
|                         |  |                     |        |  |                            |     |                             |  |        |                                                |  |                       |  |                                |  |               | 
|Dr. Jim Wright           |  |                     | 55,500 |  |                            | Nil |                             |  | 42,200 |                                                |  | Nil                   |  | N/A                            |  | Nil           | 



| | (1) | In determining the fair value of these option awards,
the Black-Scholes valuation methodology was used with the following assumptions: (i) expected life of five years; (ii) volatility
of 135%; (iii) risk free interest rate of 3%; and (iv) no dividend yield. The Corporation has decided to use the Black-Scholes
valuation methodology because it is equivalent to the option value reported in the Corporation’s consolidated financial
statements.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | Mr. Abramson resigned from the Board effective December
10, 2013.
| | --- | -----------------------------------------------------------------



During the fiscal
year ended May 31, 2013, each director who was not an officer of the Corporation was entitled to receive 15,000 share options
(the Chair received 100,000) and, at his election, Common Shares, deferred share units and/or cash compensation for attendance
at the Board committee meetings. Compensation consisted of an annual fee of $15,000 (the Chair received $35,000) and $1,500 per
Board meeting attended ($4,500 to the Chair of a Board meeting). Members of the Audit Committee received an annual fee of $8,000
(the Chair received $10,000). Each member of the Compensation Committee and Corporate Governance and Nominating Committee received
an annual fee of $5,000 per committee. Board members (including the Chair) receive $500 for meetings held via conference call.
There have not been any changes to the fees from the prior year. Non-executive directors are reimbursed for any out-of pocket
travel expenses incurred in order to attend meetings. Executive directors are not entitled to directors’ compensation or
reimbursement of travel expenses.



Directors are entitled
to participate in the DSU Plan. None of our directors except for Dr. Aiping Young participated in this plan in the fiscal years
ended May 31, 2013 or 2012.



Management Contracts



Under the employment
agreement with President and Chief Executive Officer of the Corporation, Dr. Aiping Young, dated September 21, 2006, as amended
on May 29, 2012, Dr. Young’s salary for fiscal 2013 was $340,937 and she was entitled to an annual car allowance of
$12,000. This agreement provided for a notice period equal to 18 months plus one additional month for each year of employment
under the agreement in the event of termination without cause or a resignation. It also provided that, if within 36 months of
a change of control of Lorus, Dr. Young’s employment was terminated without cause or if she terminated the agreement with
good reason as defined in the agreement, then she was entitled to receive the equivalent of two years of her basic salary plus
one month’s salary for each year under the agreement, plus an annual bonus prorated over the severance period (based on
the bonus paid in respect of the last completed fiscal year). Dr. Young is also entitled to benefits coverage for the severance
period or a cash payment in lieu thereof. In March 2014, Dr. Young’s contract was terminated, and the Company paid her 26
months of salary and bonus, as well as payment in lieu of benefits, in accordance with the terms of the agreement. The total compensation
paid to Dr. Young following her departure from the Company was approximately $1.1 million.



Under the employment
agreement with our Director of Finance of the Corporation, Ms. Elizabeth Williams, dated May 31, 2004, Ms. Williams’ salary
for fiscal 2013 was $70,000. Ms. Williams currently provides services on a part-time basis. This agreement provides for a notice
period equal to the greater of one month and the applicable notice entitlement under employment legislation in the event of termination.
Ms. Williams reports to the Chief Executive Officer. The bonus and options allocation for the Director of Finance is recommended
to the Board by the Chief Executive Officer. Ms. Williams is entitled to four weeks of paid vacation, prorated to reflect a period
of employment less than a full calendar year.



33







Under the employment
agreement with our Vice President of Research of the Corporation, Dr. Yoon Lee, dated May 5, 2008, Dr. Lee’s salary for
fiscal 2013 was $139,530. This agreement provides for a notice period equal to four months plus one additional month for each
year of employment, to a maximum of 12 months. Dr. Lee reports to the Chief Business Officer. The bonus and options allocation
of the Vice President of Research is recommended to the Board by the Chief Executive Officer. Dr. Lee is entitled to five weeks
of paid vacation, prorated to reflect a period of employment less than a full calendar year.



Salary and bonus amounts
for each of the Named Executive Officers paid during the fiscal year 2013 were as set out in the Summary Compensation Table above.



Equity Compensation Plans



The following table sets forth certain
details as at the end of the fiscal year ended May 31, 2013 with respect to compensation plans pursuant to which equity securities
of the Company are authorized for issuance.



|                                                   |  | Number of Shares to be
    
    issued upon exercise of 
    outstanding options, 
    warrants and rights 
(a) |           |  | Weighted- average exercise
    price of 
    outstanding 
    options, 
    warrants and 
    rights (b) |  |    | Number of Shares remaining
    
    available for future issuance 
    under the equity 
    compensation plans 
    (Excluding Shares reflected 
    in Column (a)) 
(c) |  |   | Total options, warrants 
and rights outstanding 
    and available for grant  
    (a) + (c) | 
|-------------------------------------------------- |  | --------------------------------------------------------------------------------------------------------------- | --------- |  | -------------------------------------------------------------------------------------------------------- |  | -- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |  | - | -------------------------------------------------------------------------------------------- | 
|Plan Category                                      |  | Number                                                                                                          |           |  | % of Shares
    outstanding                                                                              |  |    |                                                                                                                                                                           |  |   | Number                                                                                       | 
|Equity compensation plans approved by shareholders |  |                                                                                                                 | 4,138,116 |  |                                                                                                          |  | 10 | %                                                                                                                                                                         |  | $ | 0.46                                                                                         | 



Share Option Plan



The share option plan
of the Corporation (the “Share Option Plan”) was established to advance the interests of Lorus by:



| | · | providing
                                         Eligible Persons (as defined below) with additional incentives;
| | - | ------------------------------------------------------------------------------------------------------------------



| | · | encouraging
                                         stock ownership by Eligible Persons;
| | - | -----------------------------------------------------------------------------------------



| | · | increasing
                                         the interest of Eligible Persons in the success of Lorus;
| | - | -------------------------------------------------------------------------------------------------------------



| | · | encouraging
                                         Eligible Persons to remain loyal to Lorus; and
| | - | ---------------------------------------------------------------------------------------------------



| | · | attracting
                                         new Eligible Persons to Lorus.
| | - | ----------------------------------------------------------------------------------



The
Compensation Committee, as authorized by the Board administers theShare OptionPlan and makes recommendations to the Board for grants under the plan. The maximum total number of Common Shares available for
issuance from treasury under the Share Option Plan, together with the DSU Plan, the alternate compensation plan of the Corporation
(the “ACP” and collectively with the Share Option Plan and the DSU Plan, the “Plans”) and
any other security based compensation arrangement is 15% of the Corporation’s issued and outstanding Common Shares at any
given time. Any exercise of options pursuant to the Share Option Plan will make new option grants available under the Share Option
Plan, provided that the maximum number of Common Shares reserved for issuance collectively under the Plans may not exceed 15%
of the Corporation’s issued and outstanding Common Shares at any given time.



34







The exercise price
of options granted under the Share Option Plan is established by the Board and will be equal to the closing market price of the
Common Shares on the TSX on the last trading day preceding the date of grant. If there is no trading on that date, the exercise
price will be the average of the bid and ask on the TSX on the last trading date preceding the date of grant. If not otherwise
determined by the Board, an option granted under the Share Option Plan will vest as to 50% on the first anniversary of the date
of grant of the option and an additional 25% on the second and third anniversaries after the date of grant. The Board fixes the
term of each option when granted, but such term may not be greater than 10 years from the date of grant.If the date on which an option expires pursuant to an option agreement occurs during, or within 10 days after the last day of,
a black out period or other restriction period imposed on the trading of Common Shares by the Corporation, the expiry date for
the option will be the last day of the 10-day period. Options are personal to the participant and a participant may not transfer
an option except in accordance with the Share Option Plan.



The Board may, its
sole discretion, amend, suspend or terminate the Share Option Plan or any portion of it at any time in accordance with applicable
legislation, without obtaining the approval of shareholders. Any amendment to any provision of the Share Option Plan is subject
to any required regulatory or Shareholder approval. The Corporation is, however, required to obtain the approval of the shareholders
for any amendment related to (i) the maximum number of Common Shares reserved for issuance under the Share Option Plan, and under
any other security based compensation arrangements of the Corporation; (ii) a reduction in the exercise price for options held
by insiders of the Corporation; and (iii) an extension to the term of options held by insiders or the Corporation. In addition,
the Corporation is required to obtain the approval of the approval of the shareholders for any amendment related to the increase
in the limits on the grants of options to insiders of the Corporation and any shareholder approval required in respect of an amendment
to increase such limits shall exclude shall exclude the votes attaching to Common Shares, if any, held by eligible persons who
are insiders of the Corporation.



If an option holder
is terminated without cause, resigns or retires, each option held by such option holder that has vested will cease to be exercisable
three months after the option holder’s termination date. Any portion of an option that has not vested on or prior to
the termination date will expire immediately. If an option holder is terminated for cause, each option that has vested will cease
to be exercisable immediately upon the Corporation’s notice of termination. Any portion of an option that has not vested
on or prior to the termination date will expire immediately.



During
the period from June 1, 2012 to May 31, 2013, options to purchase 1,780,000 Common Shares were granted under theShare
OptionPlan at an exercise price of $0.475 per Common Share. During the
year ended May 31, 2013, we granted options to employees, other than executive officers of the Corporation, to purchase 320,000
Common Shares, being 18% of the total incentive stock options granted during the year to employees, executive officers and directors.
SinceMay 31, 2013, there have been 6,878,004 options to purchase
Common Shares granted under theShare OptionPlan at exercise
prices ranging from $0.29 to $0.78.During this period we granted
options to employees and consultants other than executive officers of the Corporation to purchase 933,004 Common Shares, being
14% of the total stock options granted during the period to employees, executive officers, consultants and directors.



Alternate Compensation Plan



The Corporation has
an ACP Plan which enables Lorus to meet its obligations to pay directors’ fees, salary and performance bonuses to certain
employees in the form of Common Shares. The ACP Plan permits the Corporation to, in circumstances considered appropriate by the
Board, encourage the ownership of equity of the Corporation by its directors and senior employees (“ACP Participants”),
enhance the Corporation’s ability to retain key personnel and reward significant performance achievements while preserving
the cash resources of the Corporation.



Under the ACP Plan,
ACP Participants have the option of receiving director’s fees, salary, bonuses or other remuneration, as applicable (“Remuneration”)
by the allotment and issuance from treasury of such number of Common Shares as will be equivalent to the cash value of the Remuneration
determined by dividing the Remuneration by the weighted average closing share price for the five (5) trading days prior to payment
date (the “5-day VWAP”). The issue price of Common Shares issued under the ACP is the 5-day VWAP.Upon ceasing to be an ACP Participant, such ACP Participant will no longer be eligible to receive Common Shares under the
ACP Plan and any amounts owing to such ACP Participant shall be paid without reference to the ACP Participant.



35







The maximum number
of Common Shares reserved for issuance under the ACP Plan, when combined with the Share Option Planand the DSU Plan must not exceed 15% of the Corporation’s issued and outstanding Common Shares at any given time.



There were no Common
Shares issued under the ACP Plan during the fiscal year ended May 31, 2013. Since
May31, 2013, there have been no Common Shares issued under theACPPlan.



The Board may, at
any time and from time to time, amend, suspend or terminate the ACP Plan without Shareholder approval, provided that no such amendment,
suspension or termination may be made without obtaining any required approval of any regulatory authority or stock exchange. Notwithstanding
the foregoing, the Board may not, without the approval of the shareholders, make amendments to the ACP Plan to increase the maximum
number of Common Shares issuable under the ACP Plan, or to amend the provisions regarding Shareholder approval.



Deferred Common Share Units Plan



The Corporation adopted
the DSU Planon April 17, 2000, pursuant to whichparticipating
directors and senior officers (“DSU Participants”) may elect to receive either a portion or all of their remuneration
from the Corporation in deferred share units. Such remuneration includes all amounts payable in cash or Common Shares (subject
to election otherwise under the DSU Plan) to a DSU Participant by the Corporation or a subsidiary of the Corporation in respect
of the services provided to the Corporation or subsidiary by the DSU Participant in any calendar year by such DSU participant,
including (a): in the case of a director, (i) annual Board or committee of the Board or advisory retainer fees, (ii) fees for
attending meetings of the Board or a committee of the Board, and (iii) fees for serving as chairman or chairwoman of any committee
of the Board, but, for greater certainty, excluding amounts payable to a DSU Participant as a reimbursement for expenses incurred
in attending meetings; and (b): in the case of a senior officer, those services for which a salary or cash bonus would normally
be paid, provided that the relevant performance criteria which serve as a basis for the granting of such bonuses have been met.



Under the DSU Plan,
the deferred share units that DSU Participants elect to receive for remuneration earned are credited to each DSU Participant’s
account in an amount of units equal to the gross amount of remuneration to be deferred divided by the fair market value of the
Common Shares, being the closing price of the Common Shares on the TSX on the day immediately preceding the recommendation by
the Compensation Committee or such other amount as determined by the Board and permitted by the applicable regulatory authorities.
Rights respecting deferred share units are not transferable or assignable other than by will or by the laws of descent and distribution.



A DSU Participant
who has retired, resigned or been terminated without cause from all positions with the Corporation and any subsidiary of the Corporation
may redeem the deferred share units credited to the DSU Participant’s account. Subject to the approval of the Compensation
Committee, the DSU Participant may indicate what portion of the payment is to be paid in cash and what portion is to be paid in
Common Shares. A DSU Participant who has been terminated with cause may not redeem the deferred share units held by that DSU Participant
and those deferred share units so held will be deemed cancelled as of the date of termination of the DSU Participant.



The maximum number
of Common Shares reserved for issuance under the DSU Plan, when combined with the Share Option Planand the ACP Plan must not exceed 15% of the Corporation’s issued and outstanding Common Shares at any given time.



During
the period from June 1, 2012 to May 31, 2013, no deferred share units were issued to DSU Participants under theDSU
Plan.Since May 31, 2013, there have been no deferred share units
issued under the DSU Plan.



36







The Board may amend
the DSU Plan as it deems necessary or appropriate without Shareholder approval, subject to applicable corporate, securities and
tax law requirements, but no amendment will, without the consent of the DSU Participant or unless required by law, adversely affect
the rights of a DSU Participant with respect to deferred share units that have been credited to the account of the DSU Participant
at the time of such amendment to the DSU Plan. Notwithstanding the foregoing, the Board must obtain Shareholder approval to increase
to the maximum number of securities reserved for issuance under the DSU Plan or any other security based compensation arrangement,
or to amend the provisions regarding Shareholder approval.



Employee Share Purchase Plan



We have an Employee
Share Purchase Plan (“ESPP”) to assist the Corporation to retain the services of its employees, to secure and
retain the services of new employees and to provide incentives for such persons to exert maximum efforts for the success of the
Corporation. The ESPP provides a means by which employees of the Corporation and its affiliates may purchase Common Shares at
a 15% discount through accumulated payroll deductions. Eligible participants in the ESPP include all employees, including executive
officers, who work at least 20 hours per week and are customarily employed by the Corporation or an affiliate of the Corporation
for at least six months per calendar year. Generally, each offering is of three months’ duration with purchases occurring
every quarter. Participants may authorize payroll deductions of up to 15% of their base compensation for the purchase of Common
Shares under the ESPP.



During the year ended
May 31, 2013, under the ESPP, Named Executive Officers, as a group, and employees did not purchase any Common Shares pursuant
to the ESPP.Since May 31, 2013, there have been no Common
Shares purchased pursuant to the ESPP.



Option Grants During Fiscal Year
2013



The following tables
set forth the options granted to and exercised by each of the Named Executive Officers during the fiscal year ended May 31,
2013:



Option/SAR Grants During the Most
Recently Completed Financial Year

|Name
                                         and Principal Position                                                                                    |  | Securities Under Options/SARs Granted  (#) |           |     | % of Total Options/SARs Granted to Employees in Financial Year (%) |  |    | Exercise or
Base Price ($/Security) |  |   | Market Value
    of Securities Underlying Options/SARs on the Date of Grant ($/Security) |  |  | Expiration Date
|------------------------------------------------------------------------------------------------------------------------------------------------------- |  | ------------------------------------------ | --------- | --- | ------------------------------------------------------------------ |  | -- | ----------------------------------- |  | - | ---------------------------------------------------------------------------------------- |  |  | ---------------
|                                                                                                                                                        |  |                                            |           |     |                                                                    |  |    |                                     |  |   |                                                                                          |  |  |                
|Dr.
                                         Aiping Young President
                                         and Chief Executive Officer(2)             |  |                                            | 1,050,000 |     |                                                                    |  | 59 | %                                   |  | $ | 0.475                                                                                    |  |  | $              
|Ms.
                                 Elizabeth Williams Director
                                         of Finance, Acting Chief Financial Officer(3) |  |                                            | 100,000   | (1) |                                                                    |  | 6  | %                                   |  | $ | 0.475                                                                                    |  |  | $              
|Dr. Yoon Lee Vice President, Research                                                                                                                   |  |                                            | 150,000   | (1) |                                                                    |  | 8  | %                                   |  | $ | 0.475                                                                                    |  |  | $              



| | (1) | These options to purchase Common Shares are incentive
options. The options only vest upon the attainment of specific undertakings based on certain corporate performance objectives;
failing to achieve the undertakings will result in forfeiture on the specified deadline. Upon achieving the specific undertakings,
50% of the options vest followed by 25% on the first anniversary and 25% on the second anniversary of the date of granting.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | Dr. Aiping Young was named Chief Operating Officer of
the Corporation on October 28, 2013. On this date, she was replaced as Chief Executive Officer of the Corporation by William G.
Rice, Ph.D. Dr. Aiping Young departed the Corporation on March 18, 2014.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (3) | Gregory Chow was appointed as our Chief Financial Officer
on December 2, 2013.
| | --- | ------------------------------------------------------------------------------



37







Incentive Compensation Plans



Outstanding Share-Based
Awards and Option-Based Awards



The following table shows all awards outstanding
to each Named Executive Officer as at May 31, 2013:



|                              |  | Option-based Awards                                     |          
|----------------------------- |  | ------------------------------------------------------- | ---------
|Name and Principal Position   |  | Number of securities underlying unexercised options (#) |          
|Dr. Aiping Young              |  |                                                         | 275,000  
|President and Chief Executive |  |                                                         | 1,050,000
|Officer                       |  |                                                         |          
|                              |  |                                                         |          
|Ms. Elizabeth Williams        |  |                                                         | 85,000   
|Director of Finance, Acting   |  |                                                         | 62,000   
|Chief Financial Officer(2)    |  |                                                         | 100,000  
|                              |  |                                                         |          
|Dr. Yoon Lee                  |  |                                                         | 100,000  
|Vice President, Research      |  |                                                         | 67,000   
|                              |  |                                                         | 150,000  





| | (1) | These amounts are calculated based on the difference
between the market value of the securities underlying the options at the end of the fiscal year ($0.22), and the exercise price
of the options.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (2) | Gregory Chow was appointed as our Chief Financial Officer
on December 2, 2013.
| | --- | ------------------------------------------------------------------------------



Aggregated Option/SAR Exercises During
the Most Recently Completed

Financial Year and Financial Year-End
Option/SAR Values

|Name                                  |  | Securities Acquired on
    Exercise (#) |  | Aggregate Value Realized
    ($) |  |  | Unexercised Options/SARs
                                         at May
                                         31, 2013 (#) Exercisable/Unexercisable |  |  |  | Value
                                         of Unexercised in-the-Money Options/SARs
                                         at May
                                         31, 2013 ($) Exercisable/Unexercisable | 
|------------------------------------- |  | --------------------------------------- |  | -------------------------------- |  |  | -------------------------------------------------------------------------------------------------------------------------------------------------------- |  |  |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | 
|                                      |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 
|Dr. Aiping Young                      |  | Nil                                     |  | Nil                              |  |  | 275,000/1,050,000                                                                                                                                        |  |  |  | 1,375/nil                                                                                                                                                                                                               | 
|President and Chief Executive Officer |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 
|Former Chief Operating Officer        |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 
|Ms. Elizabeth Williams                |  | Nil                                     |  | Nil                              |  |  | 144,750/102,250                                                                                                                                          |  |  |  | 1,559/1,346                                                                                                                                                                                                             | 
|Director of Finance, Acting Chief     |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 
|Financial Officer                     |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 
|Dr. Yoon Lee                          |  | Nil                                     |  | Nil                              |  |  | 177,875/131,625                                                                                                                                          |  |  |  | 1,687/1,456                                                                                                                                                                                                             | 
|Vice President, Research              |  |                                         |  |                                  |  |  |                                                                                                                                                          |  |  |  |                                                                                                                                                                                                                         | 



C.           Board
practices.



Lorus is authorized
to have a board of at least one director and no more than ten. Lorus currently has six directors. Directors are elected for a
term of approximately one year, from annual meeting to annual meeting, or until an earlier resignation, death or removal. For
the dates our current directors assumed their directorships, see Item 6.A. – “Directors and Senior Management”
above.



38







Each officer serves
at the discretion of the Board or until an earlier resignation or death. There are no family relationships among any of our directors
or officers.



Our non-management
directors have no service contracts with us or our subsidiaries that provide for benefits upon termination of employment. See
“Management Contracts” above for a summary of Dr. Young’s employment agreement.



Committees of the Board of Directors



The Company has an
Audit Committee, a Nominating and Corporate Governance Committee and a Compensation Committee.



The members of these
committees during the 2013 fiscal year were as follows:



|Audit Committee                                | Denis Burger, Herbert Abramson, Warren Whitehead
|---------------------------------------------- | ------------------------------------------------
|Nominating and Corporate Governance Committee: | Herbert Abramson, Mark Vincent                  
|Compensation Committee:                        | Denis Burger, Jim Wright                        



The current members
of these committees are as follows:



|Audit Committee                                | Denis Burger, Brian Underdown, Warren Whitehead
|---------------------------------------------- | -----------------------------------------------
|Nominating and Corporate Governance Committee: | Mark Vincent, Bradley Thompson                 
|Compensation Committee:                        | Denis Burger, Jim Wright, Brian Underdown      



Compensation Committee



Composition of the Compensation Committee

The Board, upon the
advice of the Compensation Committee, determines executive compensation. From June 1, 2010 to present, the Compensation Committee
has been comprised of independent Board members Dr. Burger and Dr. Wright. Dr. Burger is chair of the Compensation Committee.
The Compensation Committee met four times during the period lasting from June 1, 2012 until May 31, 2013. For more information
on the Compensation Committee, please see the section entitled “Compensation” of the Corporation’s Corporate
Governance Practices attached hereto as Appendix A.



Members of the Compensation
Committee each have direct experience relevant to compensation matters resulting from their respective current and past activities.
The members of the Compensation Committee have experience dealing with compensation matters in comparable organizations, including
public companies, as well as companies with a strong emphasis on governance in their current and former roles as principal executives.



Compensation Objectives and Philosophy

The Compensation Committee’s
mandate is to review and advise the Board on the recruitment, appointment, performance, compensation, benefits and termination
of executive officers. The Compensation Committee also administers and reviews procedures and policies with respect to the Plans,
employee benefit programs, pay equity and employment equity and reviews executive compensation disclosure where it is publicly
disclosed.



Lorus’ executive
compensation program is designed to:



| | · | attract
                                         and retain qualified, motivated and achievement-oriented individuals by offering compensation
                                         that is competitive in the industry and marketplace;
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | align
                                         executive interests with the interests of shareholders; and
| | - | ----------------------------------------------------------------------------------------------------------



| | · | ensure
                                         that individuals continue to be compensated in accordance with their personal performance
                                         and responsibilities and their contribution to the overall objectives of the Corporation.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



39







These objectives are achieved by offering
executives and employees a compensation package that is competitive and rewards the achievement of both short-term and long-term
objectives of the Corporation. As such, our compensation package consists of three key elements:



| | · | base
                                         salary and initial share options;
| | - | -------------------------------------------------------------------------------



| | · | short-term
                                         compensation incentives to reward corporate and personal performance through potential
                                         annual cash bonuses; and
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | long-term
                                         compensation incentives related to long-term increase in share value through participation
                                         in the Share Option Plan.
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



The Compensation Committee reviews each
of these items on a stand-alone basis and also reviews compensation as a total package. Adjustments to compensation are made as
appropriate following a review of the compensation package as a whole. The Compensation Committee then makes a recommendation
to the Board for approval.



Base Salary — Initial
Share Options



In establishing base
salaries, the objective of the Compensation Committee is to establish levels that will enable Lorus to attract and retain executive
officers that can effectively contribute to the long-term success of the Corporation. Base salary for each executive officer is
determined by the individual’s skills, abilities, experience, past performance and anticipated future contribution to the
success of Lorus. The members of the Compensation Committee use their knowledge of the industry and of industry trends to assist
with the determination of an appropriate compensation package for each executive officer. In certain cases, the Compensation Committee
may recommend inclusion of automobile allowances, fitness allowances and the payment of certain professional dues as a component
of an overall remuneration package for executives.



In certain cases,
executive officers may be granted share options on the commencement of employment with Lorus in accordance with the responsibility
delegated to each executive officer for achieving corporate objectives and enhancing shareholder value in accordance with those
objectives.



Short-Term Compensation Incentives



The role of short-term
compensation incentives at Lorus is to reward corporate and personal performance. Each year, the Board approves the annual corporate
objectives encompassing scientific, clinical, regulatory, business and corporate development and financial criteria. The annual
cash bonus for the executive officers is based, at least in part, on the level of achievement of these annual objectives. One
hundred percent of the President and Chief Operating Officer’s and seventy-five percent of the other executive officers’
cash bonus is based on the level of achievement of corporate objectives. The balance of the other executive officers’ bonus
is based on achievement of individual/departmental objectives.



All corporate and
executive officer objectives are reviewed by the Compensation Committee and approved by the Board. The Compensation Committee
recommends to the Board the awarding of bonuses, payable in cash, stock or share options, to reward extraordinary individual performance.



For each executive
officer, during the fiscal year ended May 31, 2013, the annual cash bonuses ranged from 15% to 40% of base salary when all
corporate and individual executive officer objectives were achieved.



Cash bonuses are determined
as soon as practicable after the end of the fiscal year and, for the Named Executive Officers (as defined hereinafter), are included
in the Summary Compensation Table in the year in respect of which they are earned.



40







Long-Term Incentive Plan



The role of long-term
compensation incentives at Lorus is to reward an executive’s contribution to the attainment of Lorus’ long-term objectives,
align an executive’s performance with the long-term performance of Lorus and to provide an additional incentive for an executive
to enhance shareholder value. Long-term incentive compensation for directors, officers, employees and consultants is reviewed
annually and is accomplished through the grant of share options under our Share Option Plan.



The number of options
granted for certain executives of Lorus for the fiscal year ended May 31, 2013 was based on achievement of both corporate and
executive officer objectives. The Compensation Committee approves the allocation of options and options are priced using the closing
market price of the Common Shares on the TSX on the last trading day prior to the date of grant. Options to purchase Common Shares
expire ten years from the date of grant and vest over a term determined by the Compensation Committee. The Compensation
Committee takes into account previous grants of options when considering new grant of options.



The option grants
for Named Executive Officers are included in the Summary Compensation Table in the year that they are granted.



Performance Metrics



The performance of
the Named Executive Officers for the 2013 financial year was measured in the following areas:



| | 1. | Maximizing the value of LOR-253;
| | -- | --------------------------------



| | 2. | Maximizing the value of IL-17E;
| | -- | -------------------------------



| | 3. | Maximizing the value of LOR-500;
| | -- | --------------------------------



| | 4. | Establishing at least one corporate partnership; and
| | -- | ----------------------------------------------------



| | 5. | Equity financing to establish at least one year of cash.
| | -- | --------------------------------------------------------



Each of the above
is weighted at 20%, 25%, 5%, 30% and 20%, respectively, in relation to assessment of satisfaction of overall corporate objective
and determination of any general corporate bonuses. Based on these criteria the Board assigned an achievement of 87%. Incentive
compensation related to the attainment of these objectives was paid in fiscal 2014. Similar performance metrics were established
for the year ending May 31, 2014 based on the approved business plan for the current year.



Hedge or Offset Instruments



Named Executive Officers or directors
are not permitted to purchase financial instruments that are designed to hedge or offset a decrease in market value of equity
securities granted as compensation or held, directly or indirectly, by Named Executive Officers or directors, including, for greater
certainty, prepaid variable forward contracts, equity swaps, collars, or units of exchange funds.



Risk Assessment of Compensation



The implications of the risks associated
with the Corporation’s compensation practices were not considered by the Board or a committee of the Board.



41







Audit Committee



The members of the
Audit Committee during the fiscal year ended May 31, 2013 were Herb Abramson, Denis Burger and Warren Whitehead. The current members
of the Audit Committee are Brian Underdown, Denis Burger and Warren Whitehead. Mr. Warren Whitehead is the Chairman of the Audit
Committee and has been appointed as the Financial Expert. Pursuant to Canadian securities laws, our board of directors has determined
that Messrs. Underdown, Burger and Whitehead are financially literate as all have experience in reviewing and analysing the financial
reports and ascertaining the financial position of a corporation. Mr. Burger, in his previous position as Chairman and Chief Executive
Officer of AVI Biopharma, is educated and experienced in reading and analyzing financial statements. Mr. Burger has also served
on the audit committee of three other publicly listed biotechnology companies. Mr. Underdown, in his position of Managing Director
at Lumira Capital Investment Management, is educated and experienced in reading and analysing financial statements. Mr. Underdown
also sits on the board of directors of several other publicly listed entities. Mr. Whitehead is a Certified Management Accountant
and has served as the Chief Financial Officer of Arius Research Inc. and Labopharm Inc. Additionally, we believe that Mr. Whitehead
and Mr. Burger qualify as “independent” as that term is defined in the relevant securities laws relating to the composition
of the audit committee.



Audit Committee Mandate



The Audit Committee’s
mandate is to assist the board of directors in fulfilling its oversight responsibilities. In particular, the Audit Committee:



| | (a) | serves as an independent and objective party to monitor
the integrity of our financial reporting process and systems of internal controls regarding finance, accounting, and legal compliance,
including the review of our Consolidated Financial Statements, MD&A and annual and interim results;
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (b) | identifies and monitors the management of the principal
risks that could impact our financial reporting;
| | --- | --------------------------------------------------------------------------------------------------------



| | (c) | monitors the independence and performance of our independent
auditors, including the pre-approval of all audit fees and all permitted non-audit services;
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------



| | (d) | provides an avenue of communication among the independent
auditors, management, and our board of directors; and
| | --- | ---------------------------------------------------------------------------------------------------------------



| | (e) | encourages continuous improvement of, and foster adherence
to, our policies, procedures and practices at all levels.
| | --- | --------------------------------------------------------------------------------------------------------------------



The Audit Committee is also responsible
for implementing and overseeing our whistle-blowing procedures.



D.           Employees.



As at May 31,
2013, we employed 15 full-time persons and four part-time people in research and drug development and administration
activities. Among our employees, five hold Ph.D.s, two hold M.D.s, five hold MSc degrees, one holds a DVM degree and
numerous others hold degrees and designations such as BSc, CPA(CA), CPA(California) and MBA. To encourage a focus on achieving long-term
performance, employees and members of the board of directors have the ability to acquire an ownership interest in the Company
through Lorus’ stock option and alternative compensation plans.



Our ability to develop
commercial products and to establish and maintain our competitive position in light of technological developments will depend,
in part, on our ability to attract and retain qualified personnel. There is a significant level of competition in the marketplace
for such personnel. We believe that to date we have been successful in attracting and retaining the highly skilled personnel critical
to our business. We have also chosen to outsource activities where skills are in short supply or where it is economically prudent
to do so.



None of our employees
are unionized, and we consider our relations with our employees to be good.



E.           Share
ownership.



The following table sets forth information
regarding beneficial ownership of our Common Shares as of May 31, 2013, by our executive officers and directors individually and
as a group.



42







|                                                    |  |                   |           |  |             |  |           |                                                  |  |  |                                       |  |  | Options to Purchase Shares       
|--------------------------------------------------- |  | ----------------- | --------- |  | ----------- |  | --------- | ------------------------------------------------ |  |  | ------------------------------------- |  |  | ---------------------------------
|                                                    |  | Number of
 Shares |           |  | Warrants(1) |  |           | Total Number 
of Shares 
Beneficially
    
Owned |  |  | Percentage of 
Shares
 Outstanding(+) |  |  | Number of 
Underlying 
Shares (#)
|                                                    |  |                   |           |  |             |  |           |                                                  |  |  |                                       |  |  |                                  
|Dr. Aiping H. Young(4)                              |  |                   | 221,584   |  |             |  | 125,000   |                                                  |  |  | 346,584                               |  |  |                                  
|Ms. Elizabeth Williams                              |  |                   | 427       |  |             |  | Nil       |                                                  |  |  | 427                                   |  |  |                                  
|Dr. Yoon Lee                                        |  |                   | Nil       |  |             |  | Nil       |                                                  |  |  | Nil                                   |  |  |                                  
|Dr. Jim A. Wright(3)                                |  |                   | 214,300   |  |             |  | Nil       |                                                  |  |  | 214,300                               |  |  |                                  
|Mr. Herbert Abramson(2)                             |  |                   | 8,938,041 |  |             |  | 2,444,500 |                                                  |  |  | 11,382,541                            |  |  |                                  
|Dr. Denis Burger                                    |  |                   | 51,987    |  |             |  | Nil       |                                                  |  |  | 51,987                                |  |  |                                  
|Dr. Bradley Thompson                                |  |                   | Nil       |  |             |  | Nil       |                                                  |  |  | Nil                                   |  |  |                                  
|Dr. Mark Vincent                                    |  |                   | Nil       |  |             |  | Nil       |                                                  |  |  | Nil                                   |  |  |                                  
|Mr. Warren Whitehead                                |  |                   | Nil       |  |             |  | Nil       |                                                  |  |  | Nil                                   |  |  |                                  
|All directors and executive officers as a
    group |  |                   | 9,426,439 |  |             |  | 2,569,500 |                                                  |  |  | 11,995,939                            |  |  |                                  



(+) calculated on a partially
diluted basis excluding stock options.

| | (1) | Warrants to purchase Common Shares were acquired pursuant
to a unit offering completed in August 2011.  Each warrant represents the right to acquire a Common Share at an exercise
price of $0.45. These warrants will expire in August 2016.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | (2) | In addition to Common Shares held personally, Mr. Abramson
is deemed to control the Common Shares held by Technifund Inc. in his capacity as sole owner of Technifund. Mr. Abramson resigned
from the Board on December 10, 2013.
| | --- | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

| | (3) | Of the Common Shares owned by Dr. Wright 56,141 are registered
in the name of Calliope Investments Limited.
| | --- | -----------------------------------------------------------------------------------------------------------

| | (4) | Dr. Young has been issued 780,000 deferred share units
in addition to the options disclosed. The deferred share units may be settled in Common Shares or cash at the approval of the
Board . Dr. Young departed the Corporation on March 18, 2104.
| | --- | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



See Item 6.B for a description
of arrangements pursuant to which employees may become involved in the capital of Lorus.



Item 7.          Major
Shareholders and Related Party Transactions



A.           Major
shareholders.



To the knowledge of
our directors and officers, as of the date hereof, no person or company beneficially owns, directly or indirectly, or exercises
control or direction over, 5% or more of the outstanding Common Shares, other than those discussed below.



Approximately 99%
of our ordinary Common Shares are held in Canada, and there are 78 record holders of our Common Shares in Canada. All of our shareholders
have equal voting rights.



43







The following table is based upon information supplied by officers,
directors and principal stockholders and Schedules 13D and 13G filed with the SEC, as well as Early Warning Reports and System
for Electronic Disclosure by Insiders (“SEDI”) filings with the Ontario Securities Commission.



|Name of Beneficial Owner(s)                |  | Amount and Nature of Beneficial Ownership |            |     | Percent of Class(1) | 
|------------------------------------------ |  | ----------------------------------------- | ---------- | --- | ------------------- | 
|Cormorant Global Healthcare Master Fund LP |  |                                           | 13,000,000 | (4) |                     | 
|Herbert Abramson                           |  |                                           | 8.993,041  | (2) |                     | 
|Mr. Sheldon Inwentash and Pinetree Capital |  |                                           | 14,670,000 | (3) |                     | 



(1) Based
on 122,858,327 Common Shares outstanding as of May 9, 2014 and assuming exercise of owner’s warrants only.



(2) Subsequent
to Lorus’ fiscal year ended May 31, 2013 on November 14, 2013 a Schedule 13D was filed jointly by Herbert Abramson and Technifund
Inc. On November 7, 2013, Abramson acquired directly 2,444,500 Common Shares through the exercise of warrants at a price of $0.45
per share and sold 2,444,500 shares at CDN$0.90 per share on the public market. On February 20, 2014 Mr. Abramson exercised 55,000
Common Share purchase options. Following this transaction Mr. Abramson and Technifund are deemed to control 8,993,041 Common Shares.



(3)
As reported on filings with SEDI. Mr. Sheldon Inwentash holds 3,920,000 Common Shares and 3,500,000 Common Share purchase
warrants and Pinetree Capital holds 5,750,000 Common Shares, 1,000,000 Common Share purchase warrants and $150,000 in
convertible promissory notes convertible into 500,000 Common Shares. Mr. Inwentash became a greater than 5% holder following
the June 2012 private placement. Please see ‘Related Party Transactions’ below for recent acquisitions by Mr.
Inwentash.



(4) On
April 3, 2014, Cormorant Global Healthcare Master Fund LP (“Cormorant”) filed a 13G indicating that it had acquired
13,000,000 of our Common Shares under the April 10, 2014 public offering as described above. Upon completion of the offering,
Cormorant held 11.5% of the issued and outstanding Common Shares of the Company.



B.           Related
party transactions.



Certain related parties
participated in the June 2013 private placement described above. Directors and officers, including Dr. Aiping Young, Dr. Jim Wright
and Dr. Mark Vincent, acquired an aggregate of $68,000 of the promissory notes. A company related to a Mr. Abramson, a former
director of the Company, acquired $250,000 of the promissory notes and Mr. Inwentash and his joint actors (“Mr. Inwentash”),
a related party of the Company by virtue of exercising control or direction over more than 10% of the issued and outstanding Common
Shares of the Company, acquired $100,000 of the promissory notes. These promissory notes were repaid by the Company in April 2014.



In the September
2013 convertible promissory note private placement described above, a company related to Mr. Abramson, a former director of Lorus,
acquired $100,000 of the promissory notes; Mr. Inwentash acquired $150,000 of the promissory notes; and Sprott Asset Management,
which then held more than 10% of the Common Shares of Lorus and the ability to acquire control of more than 20% of the Common
Shares of Lorus, acquired $112,000 of the promissory notes.



Mr. Inwentash participated
in the December 2013 Common Share public offering described above and acquired an aggregate of 1,820,000 Common Shares in that
offering and an aggregate of 1,300,000 Common Shares in the April 2014 public offering described above.



44







Executive Contracts



On October 25, 2013,
the Company entered into an executive employment agreement with William G. Rice, Ph.D., in connection with his appointment as
Chief Executive Officer and Chairman of the Board of the Company.



On November 29, 2013,
the Company entered into an executive employment agreement with each of Gregory K. Chow and Avanish Vellanki in connection with
their appointments as Chief Financial Officer and Chief Business Officer, respectively, of the Company.



The
employment agreements for each of Dr. Rice, Mr. Chow and Mr. Vellanki provide that if they are terminated by the Company
other than for cause, each of Dr. Rice, Mr. Chow and Mr. Vellanki would be entitled under their respective agreements to a
payment equivalent to 12 months of their respective annual base salaries at the time of termination.  Dr. Rice’s
current annual base salary represents U.S. $480,000, Mr. Chow’s current annual base salary represents U.S. $315,000 and
Mr. Vellanki’s current annual base salary represents U.S. $315,000.  They are each additionally entitled to an
amount equal to the average bonus remuneration received from the Company during the last three years of employment completed
prior to the termination date, prorated based on the number of days the executive worked during the year of the
termination.  In addition, the employment agreements for each of Dr. Rice, Mr. Chow and Mr. Vellanki provide that
certain payments related to health benefits continue to be made for a period of 12 months following termination of their
employment.



The employment agreements
of each of Dr. Rice, Mr. Chow and Mr. Vellanki also provide for the grant of options to purchase Common Shares of the Company,
at an exercise price equal to the fair market value of the shares on the dates of grant.  In connection with the execution
of his executive employment agreement, Dr. Rice received an initial grant of a fully vested option to purchase 425,000 Common
Shares at an exercise price equal to the fair market value of the Common Shares on the date of grant.  Pursuant to the terms
of his executive employment agreement, upon satisfaction of the conditions in his agreement, Dr. Rice received additional grants
of options to purchase 63,367, 781,633 and 1,680,000 Common Shares on December 10, 2013, January 29, 2014 and April 10, 2014,
respectively, at exercise prices equal to the fair market value of the Common Shares on the dates of grant.  The options
vest in accordance with the Company’s standard three year vesting term, at a rate of 50% of the shares subject to the option
vest on the one-year anniversary of the date of grant and 25% vest on each one-year anniversary thereafter.



In addition to the
option grants to Mr. Chow and Mr. Vellanki described below, Mr. Chow and Mr. Vellanki each received two additional grants of options
to purchase 425,000 Common Shares pursuant to the terms of their respective executive employment agreements, on December 10, 2013
and April 10, 2014.  Of the 425,000 options granted on December 10, 2013 to Mr. Chow and Mr. Vellanki, 200,000 vested immediately
and the remaining 225,000 options vest 50% after one year, 25% after two years and 25% after three years from the date of grant.
The options granted in April 10, 2014 vest in equal monthly installments over 36 months from the date of grant.



The employment agreements of Mr. Chow and
Mr. Vellanki also provide that, in the event of a change of control (as defined in the agreements), each of Mr. Chow and Mr. Vellanki
would be eligible to receive a payment equivalent to 18 months of their respective annual base salaries at the time of termination,
plus an amount equal to 150% of the average bonus remuneration received from the Company during the last three years of employment
completed prior to the termination date, prorated based on the number of days the executive worked during the year of the termination,
as well as continuation of the payments related to health benefits for a period of 12 months following the termination following
a change of control. The employment agreement of Dr. Rice does not include change of control provisions.



Prior to the Company entering into the
executive employment agreements with Mr. Chow and Mr. Vellanki, Lorus entered into a consulting agreement with each of Mr. Chow
and Mr. Vellanki, on November 4, 2013.  Pursuant to the consulting agreements, Mr. Chow provided services to the Company
as acting Chief Financial Officer prior to the date of his executive employment agreement and Mr. Vellanki provided services as
acting Chief Business Officer prior to the date of his executive employment agreement.  Mr. Chow and Mr. Vellanki each were
compensated at the monthly rate of $20,833 for their services and each were granted a fully vested option to purchase 425,000
Common Shares at an exercise price equal to the fair market value of the shares on the date of grant.



45







C.           Interests
of experts and counsel.



Not applicable.



Item 8.          Financial
Information



A.           Consolidated
statements and other financial information.



See Item 18 for our Consolidated Financial
Statements and other financial information.



Dividends on our Common Shares are
declared at the discretion of our board of directors. To date, we have not paid any dividends and do not expect to do so in the
foreseeable future.



B.            Significant changes.



Subsequent to the
quarter ended February 28, 2014, in April 2014, the Company completed a public offering of our Common Shares. The Company issued
a total of 56,500,000 Common Shares at a purchase price of $0.50 per Common Share, including 6,500,000 Common Shares sold pursuant
to the partial exercise of an over-allotment option on April 22, 2014, for aggregate gross proceeds of $28,250,000.



Subsequent to the
quarter ended February 28, 2014, then outstanding warrants exercisable for the purchase of 2,930,000 Common Shares were exercised
on April 1, 2014, providing the Company with $1,318,500 in additional proceeds.



In April 2014, the
Company repaid the $918,000 in then outstanding promissory notes due in June 2014, and the $150,000 then outstanding loan agreements
due in September 2015, and all accrued and unpaid interest on the notes.



In April 2014,
pursuant to the terms of her executive employment agreement, the Company paid cash compensation to Dr. Aiping Young of
approximately $1.1 million following her departure from the Company. The Company also issued to Dr. Young 780,000 Common Shares
in satisfaction of the deferred share unit grant previously made to Dr. Young on April 12, 2012.



Item 9.          The
Offer and Listing



Not applicable, except for Item 9.A.4. and Item 9.C.



A.           Offer
and listing details.



Price Range of Common Stock and Trading Markets



Our Common Shares,
without par value, are currently listed on the TSX under the symbol “LOR”. The following table sets out the price
ranges and trading volumes of our Common Shares on the TSX for the periods indicated below.



46







|                                    |  | TSX (CDN$) |     
|----------------------------------- |  | ---------- | ----
|Five most recent full fiscal years: |  | High       |     
|Year ended May 31, 2013             |  |            | 0.64
|Year ended May 31, 2012             |  |            | 0.72
|Year ended May 31, 2011             |  |            | 2.55
|Year ended May 31, 2010             |  |            | 3.90
|Year ended May 31, 2009             |  |            | 0.16
|                                    |  |            |     
|Year ended May 31, 2013             |  |            | 0.64
|Quarter ended May 31, 2013          |  |            | 0.30
|Quarter ended February 29, 2013     |  |            | 0.45
|Quarter ended November 30, 2012     |  |            | 0.48
|Quarter ended August 31, 2012       |  |            | 0.64
|                                    |  |            |     
|Year ended May 31, 2012             |  |            | 0.72
|Quarter ended May 31, 2012          |  |            | 0.59
|Quarter ended February 29, 2012     |  |            | 0.25
|Quarter ended November 30, 2011     |  |            | 0.37
|Quarter ended August 31, 2011       |  |            | 0.72
|                                    |  |            |     
|Most recent six months:             |  |            |     
|April 2014                          |  |            | 0.59
|March 2014                          |  |            | 0.77
|February 2014                       |  |            | 0.88
|January 2014                        |  |            | 0.70
|December 2013                       |  |            | 0.65
|November 2013                       |  |            | 1.04



B.           Plan
of distribution.



Not applicable.



C.           Markets.



See Item 9.A.



D.           Selling
shareholders.



Not applicable.



E.           Dilution.



Not applicable.



F.           Expense
of the issue.



Not applicable.



Item 10.         
Additional Information



A.           Share
capital.



Not applicable.



B.           Memorandum
and articles of association.



We are incorporated
pursuant to the laws of Canada. Our articles of incorporation(“Articles”) and by-laws provide no restrictions
as to the nature of our business operations. Under Canadian law, a director must inform us, at a meeting of the board of directors,
of any interest in a material contract or proposed material contract with us. Directors may not vote in respect of any such contracts
made with us or in any such contract in which a director is interested, and such directors shall not be counted for purposes of
determining a quorum. However, these provisions do not apply to (i) a contract relating primarily to their remuneration as
a director, officer, employee or agent of the Corporation or affiliate, (ii) a contract for their indemnity or insurance
as permitted under the Canada Business Corporations Act, or (iii) a contract with an affiliate.



47







We are
authorized to issue an unlimited number of Common Shares. Our shareholders have no rights to share in our profits, are
subject to no redemption or sinking fund provisions, have no liability for further capital calls and are not subject to any
discrimination due to number of Common Shares owned. By not more than 50 days nor less than seven days in advance of a
dividend, the Board may establish a record date for the determination of the persons entitled to such dividend.



The rights of holders
of our Common Shares can be changed at any time in a shareholder meeting where the modifications are approved by 66 2/3% of the
Common Shares represented by proxy or in person at a meeting at which a quorum exists.



All holders of our
Common Shares are entitled to vote at annual or special meetings of shareholders, provided that they were shareholders as of the
record date. The record date for shareholder meetings may precede the meeting date by no more than 50 days and not less than
21 days, provided that notice by way of advertisement is given to shareholders at least seven days before such record date.
Notice of the time and place of meetings of shareholders may not be less than 21 nor greater than 50 days prior to the date
of the meeting. There are no:



| | · | limitations
                                         on share ownership;
| | - | ------------------------------------------------------------------------



| | · | provisions
                                         of the Articles or by-laws that would have the effect of delaying, deferring or preventing
                                         a change of control of our company;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | by-law
                                         provisions that govern the ownership threshold above which shareholder ownership must
                                         be disclosed; and
| | - | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | conditions
                                         imposed by the Articles or by-laws governing changes in capital, but Canadian corporate
                                         law requires any changes to the terms of share capital be approved by 66.66% of the Common
                                         Shares represented by proxy or in person at a shareholders’ meeting convened for
                                         that purpose at which a quorum exists.
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Common Shares



Each holder of record
of Common Shares, without par value, is entitled to one vote for each share held on all matters properly submitted to the shareholders
for their vote, except matters which are required to be voted on as a particular class or series of stock. Cumulative voting for
directors is not permitted.



Holders of
outstanding Common Shares are entitled to those dividends declared by the board of directors out of legally available funds. In
the event of liquidation, dissolution or winding up our affairs, holders of Common Shares are entitled to receive, pro rata, our
net assets available after provision has been made for the preferential rights of the holders of preferred stock,including any surplus available after such event of liquidation, dissolution
or winding up of the affairs of the Corporation. Holders of outstanding Common Shares have no pre-emptive, conversion or
redemption rights. All of the issued and outstanding Common Shares are, and all unissued Common Shares, when offered and sold
will be, duly authorized, validly issued, fully paid and non-assessable. To the extent that additional Common Shares may be issued
in the future, the relative interests of the then existing shareholders may be diluted. There were 42,251,081 Common Shares issued
and outstanding at May 31, 2013.



Common Shares Eligible for Future
Sale



Future sales of substantial
amounts of our Common Shares in the public market or even the perception that such sales may occur, could adversely affect the
market price for our Common Shares and could impair our future ability to raise capital through an offering of our equity securities.



At May 31, 2013, there
were 3,400,000 options outstanding under our stock option plans to purchase an equal number of Common Shares. The outstanding
options are exercisable at a weighted average price per share of $0.46. In addition, there were 780,000 deferred share units which
may be redeemed for Common Shares of the Company



48







As at May
31, 2013, there were 27,000,000 Common Shares issuable upon the exercise of outstanding Common Share purchase warrants. Of
these warrants, 5,300,000 are exercisable at a purchase price of  $0.45 per share and expire in August 2016 and 22,000,000
are exercisable at a purchase price of $0.45 per share and expire in June 2014. On June 19, 2013, subsequent to our fiscal
year end, we issued an additional 918,000 warrants for Common Shares which are exercisable at a purchase price of $0.25
per share and expire in June 2015. In September 2013, we issued $600,000 in convertible promissory notes which can be
converted at a price of $0.30 per share into 2,000,000 Common Shares. In connection with the December 2013 public offering
and January 2014 closing of the over-allotment option we issued 878,370 Common Share warrants at an exercise price of $0.55
per share that expire after 24 months.



Indemnification of Executive Officers
and Directors



We have agreed to
indemnify our executive officers and directors for all costs, charges and expenses, including an amount paid to settle an action
or satisfy a judgment, reasonably incurred by them in respect of any civil, criminal or administrative action or proceeding to
which they are made a party by reason of being or having been a director or officer, if (a) they acted honestly and in good
faith with a view to our best interests, and (b) in the case of a criminal or administrative action or proceeding that is
enforced by a monetary penalty, they had reasonable grounds for believing that their conduct was lawful.



| | C. | Material contracts.
| | -- | -------------------



Other
than the agreements described below, we have not, in the two years preceding the date hereof, entered into any material agreements
other than contracts in the ordinary course of business.



| | 1. | Non-Exclusive License Agreement
                                                                                                                             between
                                                                                                                             the Company and Genentech Inc., dated May 1, 2012, for the non-exclusive right to certain patent rights.
| | -- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 2. | Lease of premises between the Company and
565991 Ontario Limited, dated July 27, 2001, as amended through March 31, 2015.
| | -- | -------------------------------------------------------------------------------------------------------------------------



| | 3. | Executive Employment Agreement between the
Company and Dr. William G. Rice, dated October 25, 2013.
| | -- | ---------------------------------------------------------------------------------------------------



| | 4. | Executive Employment Agreement between the
Company and Gregory K. Chow, dated November 29, 2013.
| | -- | ------------------------------------------------------------------------------------------------



| | 5. | Executive Employment Agreement between the
Company and Avanish Vellanki, dated November 29, 2013.
| | -- | -------------------------------------------------------------------------------------------------



| | 6. | Executive Employment Agreement between the
Company and Dr. Aiping Young, dated September 21, 2006, as amended on May 29, 2012.
| | -- | ------------------------------------------------------------------------------------------------------------------------------



| | 7. | Form of Warrant issued in connection with
the June 2012 private placement.
| | -- | --------------------------------------------------------------------------



| | 8. | Form of Promissory Note and Warrant Agreement
issued June 19, 2013.
| | -- | -------------------------------------------------------------------



| | 9. | Form of Promissory Note issued
September 26, 2013.
| | -- | --------------------------------------------------



| | 10. | Underwriting Agreement dated November
                                                                                                                              22, 2013 in connection with the December 2013 public offering.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | 11. | Underwriting Agreement dated March 27,
                                                                                                                              2014 in connection with the April 2014 public offering.
| | --- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



Please refer to Item
4 – “Business Overview” for further details on certain agreements referred to in number 1 and to “Financial
Strategy” for further details on items 7 to 11 above and to “Management Contracts” for further details on items
3 through 6 above.



D.           Exchange
controls.



There is no law or
governmental decree or regulation in Canada that restricts the export or import of capital, or affects the remittance of dividends,
interest or other payments to non-resident holders of our voting Common Shares, other than withholding tax requirements.



There is no limitation
imposed by Canadian law or by our Articles or our other charter documents on the right of a non-resident to hold or vote voting
Common Shares, other than as provided by the Investment Canada Act, the North American Free Trade Agreement Implementation
Act (Canada) and the World Trade Organization Agreement Implementation Act.



The Investment
Canada Act requires notification and, in certain cases, advance review and approval by the government of Canada of the acquisition
by a non-Canadian of control of a Canadian business, all as defined in the Investment Canada Act. Generally, the threshold
for review will be higher in monetary terms for a member of the World Trade Organization or North American Free Trade Agreement.



E.           Taxation.



49







CERTAIN UNITED STATES
FEDERAL INCOME TAX CONSIDERATIONS



We are likely to be a passive foreign investment company
for U.S. federal income tax purposes, which may adversely affect U.S. investors.



Our earnings for the current tax year
are expected to consist mostly of interest and similar income. For the purposes of U.S. federal income taxation, we believe we
are currently a passive foreign investment company (“PFIC”) and will continue to be a PFIC, at least until
we begin to earn substantial amounts of gross income from our operations. However, our status as a PFIC for any particular taxation
year cannot be determined with certainty until the close of our taxable year. Subject to certain limited exceptions, if a U.S.
person owns our Common Shares during a year when we are a PFIC, gain realized by the U.S. person from the sale of those Common
Shares would be taxed as ordinary income, rather than capital gain, and an interest charge would be added to the tax. The PFIC
rules are extremely complex, and U.S. persons should consult with their own U.S. tax advisors regarding the application of the
PFIC rules to an investment in our Common Shares.



U.S. Federal Income Tax Considerations



The following discussion is limited
to certain material U.S. federal income tax considerations relating to the purchase, ownership and disposition of the Common Shares
by U.S. Holders (as defined below). This discussion applies to U.S. Holders that purchase Common Shares pursuant to the offering
and hold such Common Shares as capital assets. This discussion is based on the U.S. Internal Revenue Code of 1986, as amended
(the “Code”), U.S. Treasury regulations promulgated thereunder and administrative and judicial interpretations
thereof, all as in effect on the date hereof and all of which are subject to change, possibly with retroactive effect. This discussion
does not address all of the U.S. federal income tax considerations that may be relevant to specific U.S. Holders in light of their
particular circumstances or to U.S. Holders subject to special treatment under U.S. federal income tax law (such as certain financial
institutions, insurance companies, broker-dealers and traders in securities or other persons that generally mark their securities
to market for U.S. federal income tax purposes, tax-exempt entities, retirement plans, regulated investment companies, real estate
investment trusts, certain former citizens or residents of the United States, persons who hold Common Shares as part of a “straddle,”
“hedge,” “conversion transaction,” “synthetic security” or integrated investment, persons
that have a “functional currency” other than the U.S. dollar, persons that own (or are deemed to own) 10% or more
(by voting power or value) of our Common Shares, corporations that accumulate earnings to avoid U.S. federal income tax, partnerships
and other pass-through entities, and investors in such pass-through entities). This discussion does not address any U.S. state
or local or non-U.S. tax considerations or any U.S. federal estate, gift or alternative minimum tax considerations.



As used in this discussion, the term
“U.S. Holder” means a beneficial owner of the Common Shares that is, for U.S. federal income tax purposes, (1) an
individual who is a citizen or resident of the United States, (2) a corporation (or entity treated as a corporation for U.S.
federal income tax purposes) created or organized in or under the laws of the United States, any state thereof, or the District
of Columbia, (3) an estate the income of which is subject to U.S. federal income tax regardless of its source or (4) a
trust (x) with respect to which a court within the United States is able to exercise primary supervision over its administration
and one or more United States persons have the authority to control all of its substantial decisions or (y) that has elected
under applicable U.S. Treasury regulations to be treated as a domestic trust for U.S. federal income tax purposes.



If an entity treated as a partnership
for U.S. federal income tax purposes holds the Common Shares, the U.S. federal income tax considerations relating to an investment
in the Common Shares will depend in part upon the status and activities of such entity and the particular partner. Any such entity
should consult its own tax advisor regarding the U.S. federal income tax considerations applicable to it and its partners of the
purchase, ownership and disposition of the Common Shares.



Persons holding Common Shares should consult their own tax
advisors as to the particular tax considerations applicable to them relating to the purchase, ownership and disposition of Common
Shares, including the applicability of U.S. federal, state and local tax laws and non-U.S. tax laws.



50







Distributions



Subject to the discussion below under “Passive Foreign
Investment Company Considerations,” a U.S. Holder that receives a distribution with respect to the Common Shares generally
will be required to include the gross amount of such distribution (before reduction for any Canadian withholding taxes) in gross
income as a dividend when actually or constructively received to the extent of the U.S. Holder’s pro rata share of our current
and/or accumulated earnings and profits (as determined under U.S. federal income tax principles). To the extent a distribution
received by a U.S. Holder is not a dividend because it exceeds the U.S. Holder’s pro rata share of our current and accumulated
earnings and profits, it will be treated first as a tax-free return of capital and reduce (but not below zero) the adjusted tax
basis of the U.S. Holder’s Common Shares. To the extent the distribution exceeds the adjusted tax basis of the U.S. Holder’s
Common Shares, the remainder will be taxed as capital gain. Because we may not calculate our earnings and profits under U.S. federal
income tax principles, U.S. Holders should expect all distributions to be reported to them as dividends.



The U.S. dollar value of any distribution on the Common
Shares made in Canadian dollars generally should be calculated by reference to the exchange rate between the U.S. dollar and the
Canadian dollar in effect on the date of receipt (or deemed receipt) of such distribution by the U.S. Holder regardless of whether
the Canadian dollars so received are in fact converted into U.S. dollars at that time. If the Canadian dollars received are converted
into U.S. dollars on the date of receipt (or deemed receipt), a U.S. Holder generally should not recognize currency gain or loss
on such conversion. If the Canadian dollars received are not converted into U.S. dollars on the date of receipt (or deemed receipt),
a U.S. Holder generally will have a basis in such Canadian dollars equal to the U.S. dollar value of such Canadian dollars on
the date of receipt (or deemed receipt). Any gain or loss on a subsequent conversion or other disposition of such Canadian dollars
by such U.S. Holder generally will be treated as ordinary income or loss and generally will be income or loss from sources within
the United States for U.S. foreign tax credit purposes.



Distributions on the Common Shares that are treated as
dividends generally will constitute income from sources outside the United States for foreign tax credit purposes and generally
will constitute passive category income. Such dividends will not be eligible for the “dividends received” deduction
generally allowed to corporate shareholders with respect to dividends received from U.S. corporations. Dividends paid by a “qualified
foreign corporation” are eligible for taxation at a reduced capital gains rate rather than the marginal tax rates generally
applicable to ordinary income provided that a holding period requirement (more than 60 days of ownership, without protection from
the risk of loss, during the 121-day period beginning 60 days before the ex-dividend date) and certain other requirements are
met. However, if we are a PFIC for the taxable year in which the dividend is paid or the preceding taxable year (see discussion
below under “—Passive Foreign Investment Company Considerations”), we will not be treated as a qualified foreign
corporation, and therefore the reduced capital gains tax rate described above will not apply. Each U.S. Holder is advised to consult
its tax advisors regarding the availability of the reduced tax rate on dividends.



If a U.S. Holder is subject to Canadian withholding tax
on dividends paid on the holder’s Common Shares, the U.S. Holder may be eligible, subject to a number of complex limitations,
to claim a credit against its U.S. federal income tax for the Canadian withholding tax imposed on the dividends. A U.S. Holder
may claim a deduction for the Canadian withholding tax in lieu of a credit, but only for a year in which the U.S. Holder elects
to do so for all creditable foreign income taxes. The rules governing the foreign tax credit are complex. Each U.S. Holder is
advised to consult its tax advisor regarding the availability of the foreign tax credit under its particular circumstances.



Sale, Exchange or Other Disposition of Common Shares



Subject to the discussion below under “Passive Foreign
Investment Company Considerations,” a U.S. Holder generally will recognize capital gain or loss for U.S. federal income
tax purposes upon the sale, exchange or other disposition of Common Shares. The amount of gain recognized will equal the excess
of the amount realized (i.e., the amount of cash plus the fair market value of any property received) over the U.S. Holder’s
adjusted tax basis in the Common Shares sold or exchanged. The amount of loss recognized will equal the excess of the U.S. Holder’s
adjusted tax basis in the Common Shares sold or exchanged over the amount realized. Such capital gain or loss generally will be
long-term capital gain or loss if, on the date of sale, exchange or other disposition, the Common Shares were held by the U.S.
Holder for more than one year. Net long-term capital gain derived by a non-corporate U.S. Holder currently is subject to tax at
reduced rates. The deductibility of a capital loss is subject to limitations. Any gain or loss recognized from the sale, exchange
or other disposition of Common Shares will generally be gain or loss from sources within the United States for U.S. foreign tax
credit purposes.



51







Passive Foreign Investment Company Considerations



In general, a corporation organized outside the United
States will be treated as a PFIC in any taxable year in which either (1) at least 75% of its gross income is “passive
income” or (2) on average at least 50% of the average quarterly value of its assets is attributable to assets that
produce passive income or are held for the production of passive income. Passive income for this purpose generally includes, among
other things, dividends, interest, royalties, rents, and gains from commodities transactions and from the sale or exchange of
property that gives rise to passive income. In determining whether a foreign corporation is a PFIC, a proportionate share of the
items of gross income and assets of each corporation in which it owns, directly or indirectly, at least a 25% interest (by value)
are taken into account.



We believe we were a PFIC for our taxable year ended May
31, 2013. Based on the nature of our business, the projected composition of our gross income and the projected composition and
estimated fair market values of our assets, we expect to be a PFIC for our taxable year ending May 31, 2014. However, the determination
of our PFIC status is made annually after the close of each taxable year and it is difficult to predict before such determination
whether we will be a PFIC for any given taxable year. Even if we determine that we are not a PFIC after the close of a taxable
year, there can be no assurance that the Internal Revenue Service (the “IRS”) will agree with our conclusion.
No assurance can be provided regarded our PFIC status, and neither we nor our United States counsel expresses any opinion with
respect to our PFIC status for the taxable year ended May 31, 2013 or for any other taxable year.



If we are a PFIC at any time when a U.S. Holder owns Common
Shares, such U.S. Holder will generally be subject to federal tax under the excess distribution regime on (1) distributions
paid during a taxable year that are greater than 125% of the average annual distributions paid in the three preceding taxable
years, or, if shorter, the U.S. Holder’s holding period for the Common Shares, and (2) any gain recognized on a sale,
exchange or other disposition (which would include a pledge) of Common Shares. Under the excess distribution regime, the U.S.
Holder’s tax liability will be determined by allocating such distribution or gain ratably to each day in the U.S. Holder’s
holding period for the Common Shares. The amount allocated to the current taxable year (i.e., the year in which the distribution
occurs or the gain is recognized) and any year prior to the first taxable year in which we were a PFIC in the holding period will
be taxed as ordinary income earned in the current taxable year. The amount allocated to other taxable years will be taxed at the
highest marginal rate in effect (for individuals or corporations as applicable) for ordinary income in each such taxable year,
and an interest charge, generally that applicable to the underpayment of tax, will be added to the tax. Once we are a PFIC with
respect to a particular U.S. Holder, we generally will remain a PFIC with respect to the U.S. Holder, unless we cease to meet
the gross income and asset tests described above and the U.S. Holder makes a “deemed sale” election with respect to
all of the U.S. Holder’s Common Shares. If such election is made, the U.S. Holder will be deemed to have sold the Common
Shares held at their fair market value on the last day of the last taxable year in which we qualified as a PFIC, and any gain
from such deemed sale would be taxed under the excess distribution regime described above. After the deemed sale election, the
U.S. Holder’s Common Shares would not be treated as Common Shares of a PFIC unless we subsequently became a PFIC.



If we are a PFIC for any taxable year during which a U.S.
Holder holds the Common Shares and one of our non-United States subsidiaries is also a PFIC (i.e., a lower-tier PFIC), the U.S.
Holder will be treated as owning a proportionate amount (by value) of the Common Shares of the lower-tier PFIC and will be subject
to the rules described above on certain distributions by the lower-tier PFIC and a disposition (or deemed disposition) of Common
Shares of the lower-tier PFIC, even though the U.S. Holder would not receive the distributions or the proceeds from the disposition
of the Common Shares of the lower-tier PFIC. Each U.S. Holder is advised to consult its tax advisors regarding the application
of the PFIC rules to any of our subsidiaries.



The tax considerations that would apply if we were a PFIC
would be different from those described above if a U.S. Holder were able to make a valid “qualified electing fund,”
or “QEF election.” We do not intend to provide U.S. Holders with the information required to permit them to make a
QEF election and, accordingly, prospective investors should assume that a QEF election will not be available.



52







A U.S. Holder may avoid taxation under the excess distribution
regime if the holder makes a valid “mark-to-market” election. An electing U.S. Holder generally would take into account
as ordinary income each year, the excess of the fair market value of the Common Shares held at the end of the taxable year over
the adjusted tax basis of such Common Shares. The U.S. Holder would also take into account, as an ordinary loss each year, the
excess of the adjusted tax basis of such Common Shares over their fair market value at the end of the taxable year, but only to
the extent of the excess of amounts previously included in income over ordinary losses deducted as a result of the mark-to-market
election. The U.S. Holder’s tax basis in the Common Shares would be adjusted to reflect any income or loss recognized as
a result of the mark-to-market election. Any gain from a sale, exchange or other disposition of the Common Shares in any taxable
year in which we are a PFIC, (i.e., when we meet the gross income test or asset test described above) would be treated as ordinary
income and any loss from a sale, exchange or other disposition would be treated first as an ordinary loss (to the extent of any
net mark-to-market gains previously included in income) and thereafter as a capital loss. If we cease to be a PFIC, any gain or
loss recognized by a U.S. Holder on the sale or exchange of the Common Shares would be classified as a capital gain or loss.



A mark-to-market election is available to a U.S. Holder
only for “marketable stock.” Generally, stock will be considered marketable stock if it is “regularly traded”
on a “qualified exchange” within the meaning of applicable U.S. Treasury regulations. A class of stock is regularly
traded during any calendar year during which such class of stock is traded, other than in de minimis quantities, on at least 15 days
during each calendar quarter. The Common Shares should be marketable stock as long as they are listed on the TSX and are regularly
traded. A mark-to-market election will not apply to the Common Shares for any taxable year during which we are not a PFIC, but
will remain in effect with respect to any subsequent taxable year in which we again become a PFIC. Such election will not apply
to any subsidiary that we own. Accordingly, a U.S. Holder may continue to be subject to the PFIC rules with respect to any lower-tier
PFICs notwithstanding the U.S. Holder’s mark-to-market election.



Each U.S. person who is a shareholder of a PFIC generally
must file an annual report with the IRS containing certain information, and the failure to file such report could result in the
imposition of penalties on such U.S. person and in the extension of the statute of limitations with respect to federal income
tax returns filed by such U.S. person.



The U.S. federal income tax rules relating to PFICs are
very complex. U.S. Holders are urged to consult their own tax advisers with respect to the purchase, ownership and disposition
of Common Shares, the consequences to them of an investment in a PFIC, any elections available with respect to the Common Shares
and the IRS information reporting obligations with respect to the purchase, ownership and disposition of Common Shares in the
event we are considered a PFIC.



Medicare Tax



In general, a U.S. person that is an individual or estate,
or a trust that does not fall into a special class of trusts, is subject to a 3.8% tax on the lesser of (1) the U.S. person’s
“net investment income” (or “undistributed net investment income” in the case of estates and trusts) for
the relevant taxable year and (2) the excess of the U.S. person’s “modified adjusted gross income” (or
adjusted gross income in the case of estates and trusts) for the taxable year over a certain threshold (which in the case of individuals
will be between US$125,000 and US$250,000, depending on the individual’s circumstances). A U.S. Holder’s net investment
income will include dividends and gains from the disposition of Common Shares, unless such dividends or gains are derived in the
ordinary course of the conduct of a trade or business (other than a trade or business that consists of certain passive or trading
activities). If you are a U.S. person that is an individual, estate or trust, you are encouraged to consult your tax advisor regarding
the applicability of the Medicare tax to your income and gains in respect of your investment in Common Shares.



Information Reporting with Respect to Foreign Financial
Assets



U.S. individuals that own “specified foreign financial
assets” with an aggregate fair market value exceeding either US$50,000 on the last day of the taxable year or US$75,000
at any time during the taxable year generally are required to file an information report on IRS Form 8938 with respect to such
assets with their tax returns. Significant penalties may apply to persons who fail to comply with these rules. Specified foreign
financial assets include not only financial accounts maintained in foreign financial institutions, but also, unless held in accounts
maintained by a financial institution, any stock or security issued by a non-U.S. person. Upon the issuance of future U.S. Treasury
regulations, these information reporting requirements may apply to certain U.S. entities that own specified foreign financial
assets. The failure to report information required under the current regulations could result in substantial penalties and in
the extension of the statute of limitations with respect to federal income tax returns filed by a U.S. Holder. U.S. Holders should
consult their own tax advisors regarding the possible implications of these U.S. Treasury regulations for an investment in our
Common Shares.



53







Special Reporting Requirements for Transfers to Foreign
Corporations



A U.S. Holder that acquires Common Shares generally will
be required to file Form 926 with the IRS if (1) immediately after the acquisition such U.S. Holder, directly or indirectly, owns
at least 10% of the Common Shares, or (2) the amount of cash transferred in exchange for Common Shares during the 12-month period
ending on the date of the acquisition exceeds US$100,000. Significant penalties may apply for failing to satisfy these filing
requirements. U.S. Holders are urged to contact their tax advisors regarding these filing requirements.



Information Reporting and Backup Withholding



Dividends on and proceeds from the sale or other disposition
of Common Shares may be reported to the IRS unless the U.S. Holder establishes a basis for exemption. Backup withholding may apply
to amounts subject to reporting if (1) the holder fails to provide an accurate taxpayer identification number or otherwise
establish a basis for exemption, or (2) is described in certain other categories of persons.



Any amounts withheld under the backup withholding rules
generally will be allowed as a refund or a credit against a U.S. Holder’s U.S. federal income tax liability if the required
information is furnished by the U.S. Holder on a timely basis to the IRS.



THE DISCUSSION ABOVE IS A GENERAL SUMMARY. IT DOES NOT COVER
ALL TAX MATTERS THAT MAY BE OF IMPORTANCE TO A US HOLDER. EACH US HOLDER IS URGED TO CONSULT ITS OWN TAX ADVISOR ABOUT THE TAX
CONSEQUENCES TO IT OF AN INVESTMENT IN COMMON SHARES IN LIGHT OF THE INVESTOR’S OWN CIRCUMSTANCES.



CERTAIN CANADIAN FEDERAL INCOME TAX
CONSIDERATIONS



The following is,
as of the date hereof, a summary of the principal Canadian federal income tax considerations under the Income Tax Act (Canada)
(the “Tax Act”) generally applicable to a holder of Common Shares of the Corporation who, for purposes of the
Tax Act and at all relevant times, is neither resident in Canada nor deemed to be resident in Canada for purposes of the Tax Act
and any applicable income tax treaty or convention, and who does not use or hold (and is not deemed to use or hold) Common Shares
in carrying on a business in Canada, deals at arm’s length with and is not affiliated with the Corporation and holds Common
Shares as capital property (a “Holder”). Generally, Common Shares will be considered to be capital property
to a Holder thereof provided that the Holder does not hold Common Shares in the course of carrying on a business of buying and
selling securities and such Holder has not acquired them in one or more transactions considered to be an adventure or concern
in the nature of trade.



This summary does
not apply to a Holder (i) that is a “financial institution” for purposes of the mark-to-market rules contained in
the Tax Act; (ii) that is a “specified financial institution” as defined in the Tax Act; (iii) an interest in which
is a “tax shelter investment” as defined in the Tax Act; or (iv) that has elected to report its tax results in a functional
currency other than Canadian currency. Special rules, which are not discussed in this summary, may apply to a Holder that is an
“authorized foreign bank” within the meaning of the Tax Act or an insurer carrying on business in Canada and elsewhere.
Such Holders should consult their own tax advisors.



This summary is based
upon the provisions of the Tax Act (including the regulations (“Regulations”) thereunder) in force as of the
date hereof and our understanding of the current administrative policies and assessing practices of the Canada Revenue Agency
(the “CRA”) published in writing by the CRA prior to the date hereof. This summary takes into account all specific
proposals to amend the Tax Act (and the Regulations) publicly announced by or on behalf of the Minister of Finance (Canada) prior
to the date hereof (the “Tax Proposals”) and assumes that the Tax Proposals will be enacted in the form proposed,
although no assurance can be given that the Tax Proposals will be enacted in their current form or at all. This summary does not
otherwise take into account any changes in law or in the administrative policies or assessing practices of the CRA, whether by
legislative, governmental or judicial decision or action. This summary is not exhaustive of all possible Canadian federal income
tax considerations, and does not take into account other federal or any provincial, territorial or foreign income tax legislation
or considerations, which may differ materially from those described in this summary.



54







This summary is of
a general nature only and is not, and is not intended to be, and should not be construed to be, legal or tax advice to any particular
Holder, and no representations concerning the tax consequences to any particular Holder are made. Holders should consult their
own tax advisors regarding the income tax considerations applicable to them having regard to their particular circumstances.



Dividends



Dividends paid or
credited (or deemed to be paid or credited) to a Holder by the Corporation are subject to Canadian withholding tax at the rate
of 25% unless reduced by the terms of an applicable tax treaty. For example, under the Canada-United States Income Tax Convention
(1980) (the “US Treaty”), as amended, the dividend withholding tax rate is generally reduced to 15%
in respect of a dividend paid or credited to a Holder beneficially entitled to the dividend who is resident in the U.S. for purposes
of the US Treaty and whose entitlement to the benefits of the US Treaty is not limited by the limitation of benefits provisions
of the US Treaty. Holders are urged to consult their own tax advisors to determine their entitlement to relief under the US Treaty
or any other applicable tax treaty as well as their ability to claim foreign tax credits with respect to any Canadian withholding
tax, based on their particular circumstances.



Disposition of Common Shares



A Holder generally
will not be subject to tax under the Tax Act in respect of a capital gain realized on the disposition or deemed disposition of
a Common Share, unless the Common Share constitutes or is deemed to constitute “taxable Canadian property” to the
Holder thereof for purposes of the Tax Act, and the gain is not exempt from tax pursuant to the terms of an applicable tax treaty
or convention.



In general, provided the Common Shares are listed on a “designated
stock exchange” (which currently includes the TSX) at the date of the disposition, the Common Shares will only constitute
“taxable Canadian property” of a Holder when, at any time within the 60-month period preceding the disposition: (i)
such Holder has, either alone or in combination with persons with whom the Holder does not deal at arm's length, owned 25% or more
of the issued Common Shares of any class or series of the Corporation’s capital stock, and (ii) more than 50% of the fair
market value of the Common Shares was derived directly or indirectly from one or any combination of (A) real or immovable property
situated in Canada, (B) Canadian resource properties, (C) timber resource properties, and (D) options in respect of, or interests
in, or for civil law rights in, property described in any of subparagraphs (ii)(A) to (C), whether or not the property exists.
However, and despite the foregoing, in certain circumstances the Common Shares may be deemed to be “taxable Canadian property”
under the Tax Act.



Holders whose Common
Shares may be “taxable Canadian property” should consult their own tax advisers.



F.           Dividends
and paying agents.



Not applicable.



G.           Statement
by experts.



Not applicable.



H.           Documents
on display.



We are subject to
the information and reporting requirements of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
and file periodic reports and other information with the SEC. However, as a foreign private issuer, we are exempt from the rules
and regulations under the Exchange Act prescribing the furnishing and content of proxy statements, and our officers, directors
and principal shareholders are exempt from the reporting and short-swing profit recovery provisions contained in Section 16
of the Exchange Act. Our reports and other information filed with the SEC may be inspected at the public reference facilities
maintained by the SEC at 100 F Street, N.E., Washington, D.C. 20549. Copies of these materials may be obtained at prescribed rates
from the SEC at that address. Our reports and other information can also be inspected at no charge on the SEC’s website
at www.sec.gov.



55







We are also subject
to the information and reporting requirements of the Securities Act (Ontario) and the Canada Business Corporations Act.
Such reports and information can be inspected at no charge on the website www.sedar.com.



If you are a shareholder,
you may request a copy of these filings at no cost by contacting us at:



Director of Finance
Lorus Therapeutics Inc.
2 Meridian Road
Toronto, Ontario M9W 4Z7
Canada
Phone (416) 798-1200
Fax (416) 798-2200



I.           Subsidiary
information.



Lorus currently has
one subsidiary, NuChem Pharmaceuticals Inc., a corporation incorporated under the laws of Ontario, of which Lorus owns 80% of
the issued and outstanding voting share capital and 100% of the issued and outstanding non-voting preference share capital.



Item 11.         Qualitative
and Quantitative Disclosures About Market Risk



Refer to notes 4 and
8 to the Consolidated Financial Statements contained in Item 18.



We are not exposed
to significant market risks. We do not currently have significant interest, credit or foreign currency risk.



We do not utilize
derivative financial instruments to hedge our interest rate or foreign currency rate risks.



Interest Rate Risk



The Company invests
its cash resources in liquid government and corporate debt instruments. We do not believe that the results of operations or cash
flows would be affected to any significant degree by a sudden change in market interest rates relative to interest rates on our
investments, owing to the relative short-term nature of the investments.



Credit Risk



Financial instruments
potentially exposing the Company to a concentration of credit risk consist principally of cash and cash equivalents and marketable
securities. The Company manages this credit risk by maintaining bank accounts with Schedule I banks and investing only in highly
rated Canadian securities that are traded on active markets and are capable of prompt liquidation.



Exchange Rate Sensitivity



The functional currency
of the Company is the Canadian dollar. The Company does not have significant cash balances in any foreign currencies, does not
generally invest in marketable securities denominated in currencies other than Canadian dollars and does not have significant
ongoing supply contracts or revenue sources denominated in foreign currencies. Any foreign exchange gains and losses are included
in the determination of gain or loss for the relevant period.



56







Limitations



The above discussion
includes only those exposures that exist as of May 31, 2013, and as a result, does not consider exposures or positions that could
arise after that date. The Company’s ultimate realized gain or loss with respect to interest rate and exchange rate fluctuations
would depend on the exposures that arise during the period.



Risk Factors



See Item 3.D.



Item 12.         Description
of Securities Other Than Equity Securities



Not applicable.



57







PART II



Item 13.         Defaults,
Dividends Arrearages and Delinquencies



Not applicable.



Item 14.         Material
Modifications to the Rights of Security Holders and Use of Proceeds



Not applicable.



Item 15.         Controls
and Procedures



(a)Disclosure
controls and procedures.



As of the end of our fiscal year ended
May 31, 2013, an evaluation of the effectiveness of our “disclosure controls and procedures” (as such term is defined
in Rules 13a-15(e) and 15d-15(e) under the Exchange Act), was carried out by our management under the supervision of and with
the participation of the principal executive officer and principal financial officer. Based upon on that evaluation, our principal
executive officer and principal financial officer have concluded that as of the end of that fiscal year, our disclosure controls
and procedures were effective to ensure that information required to be disclosed by us in reports that we file or submit under
the Exchange Act is (i) recorded, processed, summarized and reported within the time periods specified in SEC rules and forms
and (ii) accumulated and communicated to our management, including our principal executive officer and principal financial officer,
to allow timely decisions regarding required disclosure.



It should be noted that while our principal
executive officer and principal financial officer believe that our disclosure controls and procedures are effective and provide
a reasonable level of assurance, they do not expect that the disclosure controls and procedures or internal control over financial
reporting will prevent all errors and fraud. A control system, no matter how well conceived or operated, can provide only reasonable,
not absolute, assurance that the objectives of the control system are met.



(b)Management’s
annual report on internal control over financial reporting.



Management is responsible for establishing
and maintaining adequate internal control over our financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f)
under the Exchange Act). Our internal control system was designed to provide reasonable assurance that all transactions are accurately
recorded, that transactions are recorded as necessary to permit preparation of financial statements in accordance with IFRS, and
that our assets are safeguarded.



Management has assessed the effectiveness
of our internal control over financial reporting as at May 31, 2013. In management’s opinion, our internal control over
financial reporting is effective as at May 31, 2013. In making its assessment, management used the Committee of Sponsoring Organizations
of the Treadway Commission framework in Internal Control – Integrated Framework of 1992 to evaluate the effectiveness of
our internal control over financial reporting.



Changes in Internal Control over Financial
Reporting.



There was no change in the Corporation’s
internal control over financial reporting that occurred during the period covered by this report that has materially affected,
or is reasonably likely to materially affect, the Corporation’s internal control over financial reporting.



The design of any system of controls and
procedures is based in part upon certain assumptions about the likelihood of future events. There can be no assurance that any
design will succeed in achieving its stated goals under all potential future conditions, regardless of how remote.



58







(c)Attestation
report of the independent registered public accounting firm.



Because we are a non-accelerated
filer under the rules of the SEC, this Annual Report is not required to include, and does not include, an attestation report of
our independent registered public accounting firm with respect to our internal control over financial reporting.



(d)Changes
in internal control over financial reporting.



There have been no
changes in our internal control over financial reporting during the fiscal year ended May 31, 2013 that have materially affected,
or are reasonably likely to materially affect, our internal control over financial reporting.



Item 16.         [Reserved]



Item 16A.      Audit
Committee Financial Expert



Our board of directors
has determined that Mr. Warren Whitehead, a director of the Company and the chairman of the Audit Committee, possesses the attributes
required of an “audit committee financial expert,” and is “independent,” under applicable NYSE Amex rules.



Item 16B.      Code
of Ethics



We have adopted a
code of ethics, as such term is defined in Form 20-F, which applies to all of our officers, directors, employees and consultants.
A copy of the code of ethics is available, without charge, upon written request from our Director of Finance at our offices located
at 2 Meridian Road, Toronto, Ontario M9W 4Z7, Canada. There were no amendments to, or waivers granted under, our code of ethics
during our fiscal year ended May 31, 2013.



Item 16C.      Principal
Accountant Fees and Services



KPMG LLP has served
as our principal independent external auditor since October 1994. The total fees billed to us for professional services provided
by KPMG LLP for the fiscal years ended May 31, 2013 and 2012 are as follows:



|                   |  | 2013 |         |  | 2012 |  
|------------------ |  | ---- | ------- |  | ---- | -
|Audit Fees         |  | $    | 175,300 |  |      | $
|Audit-Related Fees |  |      | $nil    |  |      |  
|Tax Fees           |  |      | $nil    |  |      |  
|All Other Fees     |  | $    | 17,530  |  |      | $
|Total              |  | $    | 192,830 |  |      | $



Audit fees consist
of the fees paid with respect to the audit of our consolidated annual financial statements, quarterly reviews and 20-F filing
with the SEC. Tax fees relate to assistance provided with review of tax returns and assistance with specific tax issues. Other
fees consist of expenses.



Pre-Approval Policies and Procedures



The Audit Committee
of our board of directors has, pursuant to the Audit Committee charter, adopted specific responsibilities and duties regarding
the provision of services by our external auditor, currently KPMG LLP. Our charter requires Audit Committee pre-approval of all
permitted audit, audit-related and tax services.



Subject to the charter,
the Audit Committee may establish fee thresholds for a group of pre-approved services. The Audit Committee then recommends to
the board of directors approval of the fees and other significant compensation to be paid to the independent auditors.



59







No services were provided
by KPMG LLP under a de minimusexemption for our fiscal year ended May 31, 2013.



Item 16D.      Exemptions
from the Listing Standards for Audit Committees



Not applicable.



Item 16E.       Purchases
of Equity Securities by the Issuer and Affiliated Purchasers



Not applicable.



Item 16F.       Change
in Registrant’s Certifying Accountant



Not applicable.



Item 16G.      Corporate
Governance



Not applicable.



Item 16H.      Mine
Safety Disclosure



Not applicable.



60







PART III



Item 17.         Financial
Statements



We have responded to
Item 18 in lieu of responding to this Item.



Item 18.         Financial
Statements



The Consolidated Financial
Statements of Lorus Therapeutics Inc. are attached as follows:



|                                                                                                                      |  | Page
|--------------------------------------------------------------------------------------------------------------------- |  | ----
|Managements Responsibility for Financial Reporting                                                                    |  | F-1 
|Report of Independent Registered Public Accounting Firm                                                               |  | F-2 
|Consolidated Statements of Financial Position as at May 31, 2013 and May 31,  2012                                    |  | F-3 
|Consolidated Statements of Loss and Comprehensive Loss for the years ended May 31, 2013, and 2012                     |  | F-4 
|Consolidated Statement of Changes in Shareholders’ Equity for the years ended May 31, 2013, and 2012                  |  | F-5 
|Consolidated Statements of Cash Flows for the years ended May 31, 2013 and 2012                                       |  | F-6 
|Notes to Consolidated Financial Statements for the year ended May 31, 2013                                            |  | F-7 
|Consolidated Statements of Financial Position at February 28, 2014                                                    |  | F-38
|Consolidated Statements of Loss and Comprehensive Loss for the three and nine months ended February 28, 2014 and 2013 |  | F-39
|Consolidated Statement of Changes in Shareholder’s Equity for the nine months ended February 28, 2014 and 2013        |  | F-40
|Consolidated Statements of Cash Flows for the three and nine months ended February 28, 2014 and 2013                  |  | F-41
|Notes to the Consolidated Financial Statements for the three and nine months ended February 28, 2014 and 2013         |  | F-42



61







Item 19.         Exhibits



See the Exhibit Index hereto.



62







SIGNATURES



The registrant hereby certifies that it
meets all of the requirements for filing on Form 20-F and that it has duly caused and authorized the undersigned to sign this
Annual Report on its behalf.



| | LORUS THERAPEUTICS INC.
| | -----------------------
| |                        
| | By:                    
| |                        
| |                        
| |                        
| |                        



| | By: | /s/ Gregory Chow              
| | --- | ------------------------------
| |     | Name:	Gregory Chow            
| |     | Title:	Chief Financial Officer
| |     |                               
| |     | Date:	May 15th, 2014          



63







EXHIBIT INDEX





|Number              |  | Exhibit                                                                                                                                                                                                     
|------------------- |  | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
|1.1 *               |  | Articles of Incorporation.                                                                                                                                                                                  
|1.2*                |  | Articles of Arrangement.                                                                                                                                                                                    
|1.3 *               |  | By-law #2 of the Registrant.                                                                                                                                                                                
|2.11+               |  | Indemnification Agreement dated July 10, 2007 between Old Lorus and the Company.                                                                                                                            
|2.24#               |  | Share Purchase Warrant related to the June 2012 Private Placement.                                                                                                                                          
|2.25                |  | Form of Promissory Note issued June 19, 2013.                                                                                                                                                               
|2.26                |  | Form of Promissory Note issued September 26, 2013.                                                                                                                                                          
|2.27                |  | Underwriting Agreement dated November 22, 2013 in Connection with the December 2013 public
        offering.                                                                                                
|2.28                |  | Underwriting Agreement dated March 27, 2014 in Connection with the April 2014 public offering.                                                                                                              
|4.1+++              |  | Security Based Compensation Plans.                                                                                                                                                                          
|4.2+++              |  | Form of Officer and Director Indemnity Agreement.                                                                                                                                                           
|4.3 ++              |  | Amalgamation Agreement dated August 23, 1991, among the Company, Mint Gold Resources Ltd., Harry J. Hodge and Wayne Beach.                                                                                  
|4.4###^^            |  | Non-Exclusive License Agreement dated May 1, 2012 between the Company and Genentech, Inc.                                                                                                                   
|4.5+                |  | Indemnification Agreement dated July 10, 2007 between Old Lorus and the Company.                                                                                                                            
|4.8**
        4.8.1 |  | Lease of Premises between the Company and 565991 Ontario Limited,
        dated July 27, 2001.
        Lease Amending Agreement dated April 15, 2005 between the
        Company and 565991 Ontario Limited.
|4.8.2               |  | Lease Amending Agreement dated February 25, 2008 between the Company and 565991 Ontario
    Limited.                                                                                                        
|4.8.3               |  | Lease Amending Agreement dated December 15, 2010 between the Company and 565991 Ontario
    Limited.                                                                                                        
|4.8.4               |  | Lease Amending Agreement dated February 1, 2013 between the Company and 565991 Ontario
    Limited.                                                                                                         
|4.9                 |  | Executive Employment Agreement between the Company and Dr. William G. Rice, dated October 25, 2013.                                                                                                         
|4.9.1               |  | Executive Employment Agreement between the Company and Gregory K. Chow, dated November 29, 2013.                                                                                                            
|4.9.2               |  | Executive Employment Agreement between the Company and Avanish Vellanki, dated November 29, 2013.                                                                                                           
|4.12                |  | Executive Employment Agreement between the Company and Dr. Aiping Young, dated September 21, 2006, as amended on May 29, 2012.                                                                              
|8.1##               |  | List of subsidiaries.                                                                                                                                                                                       
|11.1##              |  | Code of Business Conduct and Ethics.                                                                                                                                                                        
|12.1                |  | Certification of Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act.                                                                                                                 





64







|12.2 |  | Certification of Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act.                                            
|---- |  | ---------------------------------------------------------------------------------------------------------------------------------------
|13.1 |  | Certification of Chief Executive Officer pursuant to Section 906 of the Sarbanes-Oxley Act.                                            
|13.2 |  | Certification of Chief Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act.                                            
|15.1 |  | Management Discussion and Analysis for the year ended May 31, 2013.                                                                    
|*    |  | Incorporated by reference to File 0-32001, Form 6-K, dated November 19, 2007.                                                          
|**   |  | Incorporated by reference to File 000-19763, Form 20-F, dated December 16, 2002.                                                       
|+    |  | Incorporated by reference to File 1-32001, Form 6-K, dated September 4, 2007.                                                          
|++   |  | Incorporated by reference to File 0-19763, Registration Statement on Form 20-FR, dated March 4, 1992.                                  
|+++  |  | Incorporated by reference to File 1-32001, Form 20-F, Annual Report, dated November 29, 2007.                                          
|^^   |  | Confidential treatment has been requested for portions of this document, which have been omitted and filed separately
    with the SEC.
|#    |  | Incorporated by reference to File 1-32001, Form 20-F, Annual Report dated September 27, 2012.                                          
|##   |  | Incorporated by reference to File 1-32001, Form 20-F, Annual Report, dated November 30, 2009.                                          
|###  |  | Incorporated by reference to File 1-32001, Form 20-F/A, Annual Report, dated January 11, 2013.                                         





65











Consolidated Financial Statements of



LORUS THERAPEUTICS
INC.



Years ended May 31, 2013 and 2012



66











Management’s Responsibility for Financial Reporting



The accompanying consolidated financial
statements of Lorus Therapeutics Inc. and other financial information contained in this annual report are the responsibility of
Management and have been approved by the Board of the Company.



The consolidated financial statements have
been prepared in conformity with International Financial Reporting Standards, using Management’s best estimates and judgments
where appropriate. In the opinion of Management, these consolidated financial statements reflect fairly the financial position
and the results of operations and cash flows of the Company within reasonable limits of materiality. The financial information
contained elsewhere in this annual report has been reviewed to ensure consistency with that in the consolidated financial statements.
The integrity and objectivity of data in the financial statements and elsewhere in this annual report are the responsibility of
Management.



In discharging its responsibility for the
integrity and fairness of the financial statements, management maintains a system of internal controls designed to provide reasonable
assurance, at appropriate cost, that transactions are authorized, assets are safeguarded and proper records are maintained. Management
believes that the internal controls provide reasonable assurance that financial records are reliable and form a proper basis for
the preparation of the consolidated financial statements, and that assets are properly accounted for and safeguarded. The internal
control process includes management’s communication to employees of policies that govern ethical business conduct.



The Board, through an Audit Committee,
oversees management’s responsibilities for financial reporting. This committee, which consists of three independent directors,
reviews the audited consolidated financial statements and recommends the financial statements to the Board for approval. Other
key responsibilities of the Audit Committee include reviewing the adequacy of the Company’s existing internal controls, audit
process and financial reporting with management and the external auditors.



The consolidated financial statements have
been audited by KPMG LLP, Chartered Accountants, who are independent auditors appointed by the shareholders of the Company upon
the recommendation of the Audit Committee. Their report follows. The independent auditors have free and full access to the Audit
Committee.



|/s/ William G. Rice     | /s/ Gregory Chow         
|----------------------- | -------------------------
|                        |                          
|William G. Rice         | Gregory Chow             
|Chairman, President and | Senior Vice President and
|Chief Executive Officer | Chief Financial Officer  









F-1









| |                                                                                                                                                |                                        |                                                          
| | ---------------------------------------------------------------------------------------------------------------------------------------------- | -------------------------------------- | ---------------------------------------------------------
| | kpmg LLP
        Chartered Accountants
        Bay Adelaide Centre
        333 Bay Street Suite 4600
        Toronto ON M5H 2S5
        Canada | Telephone
        Fax
        Internet | (416) 777-8500
        (416) 777-8818
        www.kpmg.ca



INDEPENDENT
AUDITORS’ REPORT OF REGISTERED PUBLIC ACCOUNTING FIRM



To the Shareholders and Board of Directors of Lorus Therapeutics
Inc.



We have audited the accompanying consolidated
financial statements of Lorus Therapeutics Inc., which comprise the consolidated statements of financial position as at May 31,
2013 and 2012, the consolidated statements of loss and comprehensive income, changes in equity and cash flows for the years
then ended, and notes, comprising a summary of significant accounting policies and other explanatory information.



Management’s Responsibility for
the Consolidated Financial Statements



Management is responsible for the preparation
and fair presentation of these consolidated financial statements in accordance with International Financial Reporting Standards
as issued by the International Accounting Standards Board, and for such internal control as management determines is necessary
to enable the preparation of consolidated financial statements that are free from material misstatement, whether due to fraud or
error.



Auditors’ Responsibility



Our responsibility is to express an opinion
on these consolidated financial statements based on our audits. We conducted our audits in accordance with Canadian generally accepted
auditing standards and the standards of the Public Company Accounting Oversight Board (United States). Those standards require
that we comply with ethical requirements and plan and perform the audit to obtain reasonable assurance about whether the consolidated
financial statements are free from material misstatement.



An audit involves performing procedures
to obtain audit evidence about the amounts and disclosures in the consolidated financial statements. The procedures selected depend
on our judgment, including the assessment of the risks of material misstatement of the consolidatedfinancial statements,
whether due to fraud or error. In making those risk assessments, we consider internal control relevant to the entity’s preparation
and fair presentation of the consolidated financial statements in order to design audit procedures that are appropriate in the
circumstances, but not for the purpose of expressing an opinion on the effectiveness of the entity’s internal control.An audit also includes evaluating the appropriateness of accounting policies used and the reasonableness of accounting
estimates made by management, as well as evaluating the overall presentation of the consolidated financial statements.



We believe that the audit evidence we have
obtained in our audits is sufficient and appropriate to provide a basis for our audit opinion.



Opinion



In our opinion, the consolidated financial
statements present fairly, in all material respects, the consolidated financial position of Lorus Therapeutics Inc. as at May 31,
2013 and 2012, and its consolidated financial performance and its consolidated cash flows for the years then ended in accordance
with International Financial Reporting Standards as issued by the International Accounting Standards Board.



Emphasis of Matter



Without qualifying our opinion, we draw
attention to Note 2(b) in the consolidated financial statements, which indicates that Lorus Therapeutics Inc. is in the development
stage and, as such, no substantial revenue has been generated from its operating activities and consequently, it is incurring losses
and negative cash flows from its activities and has a deficit of $199,959,000 and negative working capital. Accordingly, Lorus
Therapeutics Inc. depends on its ability to raise financing in order to discharge its commitments and liabilities in the normal
course of business. These conditions, along with other matters as set forth in Note 2(b), indicate the existence of a material
uncertainty that casts substantial doubt about Lorus Therapeutics Inc.’s ability to continue as a going concern.



Chartered Accountants, Licensed Public Accountants



July 11, 2013



Toronto, Canada



| | KPMG LLP is a Canadian limited liability partnership and a member firm
    of the KPMG | 
| | -------------------------------------------------------------------------------------- | 
| | network of independent member firms affiliated with KPMG International Cooperative     | 
| | (“KPMG International”), a Swiss entity.                                                | 
| | KPMG Canada provides services to KPMG LLP.                                             | 



F-2







|Lorus Therapeutics Inc.                      
|---------------------------------------------
|Consolidated Statements of Financial Position
|(Expressed in thousands of Canadian dollars) 
|                                             



|                                                        |  | May 31, |          |   | May 31, |  
|------------------------------------------------------- |  | ------- | -------- | - | ------- | -
|                                                        |  | 2013    |          |   | 2012    |  
|                                                        |  |         |          |   |         |  
|Assets                                                  |  |         |          |   |         |  
|                                                        |  |         |          |   |         |  
|Current assets:                                         |  |         |          |   |         |  
|Cash and cash equivalents (note 4)                      |  | $       | 653      |   |         | $
|Prepaid expenses and other assets                       |  |         | 365      |   |         |  
|Total current assets                                    |  |         | 1,018    |   |         |  
|                                                        |  |         |          |   |         |  
|Non-current assets:                                     |  |         |          |   |         |  
|Equipment (note 5)                                      |  |         | 17       |   |         |  
|Total non-current assets                                |  |         | 17       |   |         |  
|                                                        |  |         |          |   |         |  
|Total assets                                            |  | $       | 1,035    |   |         | $
|                                                        |  |         |          |   |         |  
|Liabilities and Shareholders' (Deficiency) Equity       |  |         |          |   |         |  
|                                                        |  |         |          |   |         |  
|Current liabilities:                                    |  |         |          |   |         |  
|Accounts payable                                        |  | $       | 713      |   |         | $
|Accrued liabilities (notes 9(g) and 14)                 |  |         | 1,103    |   |         |  
|Promissory notes payable (note 7)                       |  |         | –        |   |         |  
|Total current liabilities                               |  |         | 1,816    |   |         |  
|                                                        |  |         |          |   |         |  
|Shareholders' (deficiency) equity:                      |  |         |          |   |         |  
|Share capital (note 9):                                 |  |         |          |   |         |  
|Common shares                                           |  |         | 174,522  |   |         |  
|Stock options (note 10)                                 |  |         | 1,018    |   |         |  
|Contributed surplus                                     |  |         | 21,217   |   |         |  
|Warrants                                                |  |         | 2,421    |   |         |  
|Deficit                                                 |  |         | (199,959 | ) |         |  
|Total shareholders' (deficiency) equity                 |  |         | (781     | ) |         |  
|                                                        |  |         |          |   |         |  
|Going concern (note 2(b))                               |  |         |          |   |         |  
|                                                        |  |         |          |   |         |  
|Total liabilities and shareholders' (deficiency) equity |  | $       | 1,035    |   |         | $



See accompanying notes to consolidated
financial statements.



On behalf of the Board:



|“Warren Whitehead” |  | Director
|------------------ |  | --------
|                   |  |         
|“Jim Wright”       |  | Director



F-3







|Lorus Therapeutics Inc.                                                       
|------------------------------------------------------------------------------
|Consolidated Statements of Loss and Comprehensive Loss                        
|(Expressed in thousands of Canadian dollars, except for per common share data)
|                                                                              
|Years ended May 31, 2013 and 2012                                             
|                                                                              



|                                                                                                     |  | 2013 |        |   | 2012 |  
|---------------------------------------------------------------------------------------------------- |  | ---- | ------ | - | ---- | -
|                                                                                                     |  |      |        |   |      |  
|Revenue                                                                                              |  | $    | –      |   |      | $
|                                                                                                     |  |      |        |   |      |  
|Expenses:                                                                                            |  |      |        |   |      |  
|Research and development (notes 6 and 12)                                                            |  |      | 3,317  |   |      |  
|General and administrative (note 12)                                                                 |  |      | 2,272  |   |      |  
|Operating expenses                                                                                   |  |      | 5,589  |   |      |  
|                                                                                                     |  |      |        |   |      |  
|Finance expense (note 11)                                                                            |  |      | 6      |   |      |  
|Finance income                                                                                       |  |      | (30    | ) |      |  
|Net finance (income) expense                                                                         |  |      | (24    | ) |      |  
|                                                                                                     |  |      |        |   |      |  
|Net loss and total comprehensive loss for the year                                                   |  | $    | (5,565 | ) |      | $
|                                                                                                     |  |      |        |   |      |  
|Basic and diluted loss per common share                                                              |  | $    | (0.13  | ) |      | $
|                                                                                                     |  |      |        |   |      |  
|Weighted average number of common shares outstanding
     used in the calculation of (in thousands): |  |      |        |   |      |  
|Basic and diluted loss per common
    share                                                          |  |      | 42,251 |   |      |  



See accompanying notes to consolidated
financial statements.



F-4







|Lorus Therapeutics Inc.                                   
|----------------------------------------------------------
|Consolidated Statements of Changes in Shareholders' Equity
|(Expressed in thousands of Canadian dollars)              
|                                                          
|Years ended May 31, 2012 and 2012                         
|                                                          



|                                             |  | Common |         |  | Stock   |   |        |          |  |   | Contributed |   |  |         |        |   |       |  
|-------------------------------------------- |  | ------ | ------- |  | ------- | - | ------ | -------- |  | - | ----------- | - |  | ------- | ------ | - | ----- | -
|                                             |  | shares |         |  | options |   |        | Warrants |  |   | surplus     |   |  | Deficit |        |   | Total |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Balance, June 1, 2012                        |  | $      | 170,036 |  |         | $ | 535    |          |  | $ | 609         |   |  | $       | 21,186 |   |       | $
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Issuance of units (note 9(b)(i))             |  |        | 4,263   |  |         |   | –      |          |  |   | 1,855       |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Exercise of warrants (note 9(c)(ii)(a))      |  |        | 223     |  |         |   | –      |          |  |   | (43         | ) |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Stock-based compensation (note 10)           |  |        | –       |  |         |   | 514    |          |  |   | –           |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Forfeiture of stock options                  |  |        | –       |  |         |   | (31    | )        |  |   | –           |   |  |         | 31     |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Net loss for the year                        |  |        | –       |  |         |   | –      |          |  |   | –           |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Balance, May 31, 2013                        |  | $      | 174,522 |  |         | $ | 1,018  |          |  | $ | 2,421       |   |  | $       | 21,217 |   |       | $
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Balance, June 1, 2011                        |  | $      | 168,787 |  |         | $ | 1,212  |          |  | $ | 1,032       |   |  | $       | 18,988 |   |       | $
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Issuance of units (note 9(b)(ii))            |  |        | 1,214   |  |         |   | –      |          |  |   | 609         |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Repricing of warrants (note 9(c)(i))         |  |        | –       |  |         |   | –      |          |  |   | 239         |   |  |         | (239   | ) |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Exercise of warrants (note 9(c)(ii)(b))      |  |        | 35      |  |         |   | –      |          |  |   | (18         | ) |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Expiry of warrants (note 9(c)(ii)(b))        |  |        | –       |  |         |   | –      |          |  |   | (1,253      | ) |  |         | 1,253  |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Stock-based compensation (note 10)           |  |        | –       |  |         |   | 507    |          |  |   | –           |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Cancellation and forfeiture of stock options |  |        | –       |  |         |   | (1,184 | )        |  |   | –           |   |  |         | 1,184  |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Net loss for the year                        |  |        | –       |  |         |   | –      |          |  |   | –           |   |  |         | –      |   |       |  
|                                             |  |        |         |  |         |   |        |          |  |   |             |   |  |         |        |   |       |  
|Balance, May 31, 2012                        |  | $      | 170,036 |  |         | $ | 535    |          |  | $ | 609         |   |  | $       | 21,186 |   |       | $



See accompanying notes to consolidated
financial statements.



F-5







|Lorus Therapeutics Inc.                     
|--------------------------------------------
|Consolidated Statements of Cash Flows       
|(Expressed in thousands of Canadian dollars)
|                                            
|Years ended May 31, 2013 and 2012           
|                                            



|                                                                            |  | 2013 |        |   | 2012 |  
|--------------------------------------------------------------------------- |  | ---- | ------ | - | ---- | -
|                                                                            |  |      |        |   |      |  
|Cash flows from operating activities:                                       |  |      |        |   |      |  
|Net loss for the year                                                       |  | $    | (5,565 | ) |      | $
|Items not involving cash:                                                   |  |      |        |   |      |  
|Stock-based compensation                                                    |  |      | 514    |   |      |  
|Depreciation of equipment                                                   |  |      | 38     |   |      |  
|Finance income                                                              |  |      | (30    | ) |      |  
|Finance expense                                                             |  |      | 6      |   |      |  
|Change in non-cash operating working
    capital (note 11)                  |  |      | (52    | ) |      |  
|Cash used in operating activities                                           |  |      | (5,089 | ) |      |  
|                                                                            |  |      |        |   |      |  
|Cash flows from financing activities:                                       |  |      |        |   |      |  
|Issuance of common shares and warrants,  net of issuance
    costs (note 9) |  |      | 6,118  |   |      |  
|Exercise of warrants (note 9)                                               |  |      | 180    |   |      |  
|Issuance of promissory notes (note 7)                                       |  |      | –      |   |      |  
|Repayment of promissory notes (note 7)                                      |  |      | (900   | ) |      |  
|Interest on promissory notes                                                |  |      | (6     | ) |      |  
|Cash provided by financing activities                                       |  |      | 5,392  |   |      |  
|                                                                            |  |      |        |   |      |  
|Cash flows from investing activities:                                       |  |      |        |   |      |  
|Interest income                                                             |  |      | 30     |   |      |  
|Cash provided by investing activities                                       |  |      | 30     |   |      |  
|                                                                            |  |      |        |   |      |  
|Increase (decrease) in cash and cash equivalents                            |  |      | 333    |   |      |  
|                                                                            |  |      |        |   |      |  
|Cash and cash equivalents, beginning of year                                |  |      | 320    |   |      |  
|                                                                            |  |      |        |   |      |  
|Cash and cash equivalents, end of year                                      |  | $    | 653    |   |      | $



Supplemental cash flow information (note
11)



See accompanying notes to consolidated
financial statements.



F-6







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 1. | Reporting entity:
| | -- | -----------------



Lorus Therapeutics Inc. ("Lorus"
or the "Company") is a biopharmaceutical company focused on the discovery, research and development of anticancer therapies.
Lorus has worked to establish a diverse anticancer product pipeline, with products in various stages of development ranging from
discovery and pre-clinical to clinical stage development. The Company is a publicly listed company incorporated under the laws
of Canada. The Company's shares are listed on the Toronto Stock Exchange. The head office, principal address and records of the
Company are located at 2 Meridian Road, Toronto, Ontario, Canada, M9W 4Z7.



| | 2. | Basis of presentation:
| | -- | ----------------------



| | (a) | Statement of compliance:
| | --- | ------------------------



These consolidated financial
statements of the Company and its subsidiary as at May 31, 2013 are prepared in accordance with International Financial Reporting
Standards ("IFRS") as issued by the International Accounting Standards Board ("IASB"). The consolidated financial
statements of the Company were approved and authorized for issue by the Board of Directors on July 11, 2013.



| | (b) | Going concern:
| | --- | --------------



These consolidated financial
statements have been prepared in accordance with IFRS accounting principles applicable to a going concern using the historical
cost basis.



Management has forecasted that
the Company's current level of cash and cash equivalents, including the proceeds from the private placement completed subsequent
to year end (note 16), will not be sufficient to execute its current planned expenditures for the next 12 months without further
financing being obtained. The Company is currently in discussion with several potential investors and partners to provide additional
funding. Management believes that it will complete one or more of these arrangements in sufficient time to continue to execute
its planned expenditures without interruption. However, there can be no assurance that the capital will be available as necessary
to meet these continuing expenditures, or if the capital is available, that it will be on terms acceptable to the Company. The
issuance of common shares by the Company could result in significant dilution in the equity interest of existing shareholders.
There can be no assurance that the Company will be able to obtain sufficient financing to meet future operational needs. As a
result, there is a substantial doubt as to whether the Company will be able to continue as a going concern and realize its assets
and pay its liabilities as they fall due.



F-7







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 2. | Basis of presentation (continued):
| | -- | ----------------------------------



These consolidated financial
statements do not reflect the adjustments that would be necessary should the Company be unable to continue as a going concern
and therefore be required to realize its assets and settle its liabilities and commitments in other than the normal course of
business and at amounts different from those in the accompanying consolidated financial statements. Such amounts could be material.



| | (c) | Functional and presentation currency:
| | --- | -------------------------------------



The functional and presentation
currency of the Company and its Canadian subsidiary, NuChem Pharmaceuticals Inc. ("NuChem"), is the Canadian dollar.



| | (d) | Significant accounting judgments,
                                         estimates and assumptions:
| | --- | -----------------------------------------------------------------------------------------------------



The preparation of these consolidated
financial statements in accordance with IFRS requires management to make judgments, estimates and assumptions that affect the
application of accounting policies and reported amounts of assets and liabilities at the date of the consolidated financial statements
and reported amounts of revenue and expenses during the reporting period. Actual outcomes could differ from those estimates. The
consolidated financial statements include estimates, which, by their nature, are uncertain. The impacts of such estimates are
pervasive throughout the consolidated financial statements and may require accounting adjustments based on future occurrences.



The estimates and underlying
assumptions are reviewed on a regular basis. Revisions to accounting estimates are recognized in the period in which the estimate
is revised and in any future periods affected.



The key assumptions concerning
the future and other key sources of estimation uncertainty as of the date of the statement of financial position that have a significant
risk of causing material adjustment to the carrying amounts of assets and liabilities within the next fiscal year include:



| | (i) | Valuation of contingent liabilities:
| | --- | ------------------------------------



The Company utilizes considerable
judgment in the measurement and recognition of provisions and the Company's exposure to contingent liabilities. Judgment is required
to assess and determine the likelihood that any potential or pending litigation or any and all potential claims against the Company
may be successful. The Company must estimate if an obligation is probable as well as quantify the possible economic cost of any
claim or contingent liability. Such judgments and assumptions are inherently



F-8







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 2. | Basis of presentation (continued):
| | -- | ----------------------------------



uncertain. The increase or decrease
of one of these assumptions could materially increase or decrease the fair value of the liability and the associated expense.



| | (ii) | Valuation of tax accounts:
| | ---- | --------------------------



Uncertainties exist with respect
to the interpretation of complex tax regulations and the amount and timing of future taxable income. Currently, the Company is
accumulating tax loss carryforward balances creating a deferred tax asset. Deferred tax assets are recognized for all unused tax
losses to the extent that it is probable that taxable profit will be available against which the losses can be utilized. Management
judgment is required to determine the amount of deferred tax assets that can be recognized, based upon the likely timing and the
level of future taxable profits together with future tax planning strategies. To date, the Company has determined that none of
its deferred tax assets should be recognized. The Company's deferred tax assets are mainly comprised of its net operating losses
from prior years, prior year research and development expenses, and investment tax credits. These tax pools relate to entities
that have a history of losses, have varying expiry dates, and may not be used to offset taxable income. As well, there are no
taxable temporary differences or any tax planning opportunities available that could partly support the recognition of these losses
as deferred tax assets. The generation of future taxable income could result in the recognition of some portion or all of the
remaining benefits, which could result in an improvement in the Company's results of operations through the recovery of future
income taxes.



| | (iii) | Valuation of share-based compensation
                                         and share purchase warrants:
| | ----- | -----------------------------------------------------------------------------------------------------------



Management measures the costs
for share-based payments and share purchase warrants using market-based option valuation techniques. Assumptions are made and
judgment is used in applying valuation techniques. These assumptions and judgments include estimating the future volatility of
the share price, expected dividend yield, future employee turnover rates and future share option and share purchase warrant behaviours
and corporate performance. Such judgments and assumptions are inherently uncertain. The increase or decrease of one of these assumptions
could materially increase or decrease the fair value of share-based payments and share purchase warrants issued and the associated
expense.



F-9







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant
                                         accounting policies:
| | -- | -------------------------------------------------------------------------



| | (a) | Basis of consolidation:
| | --- | -----------------------



The consolidated financial statements
include the accounts of the Company and its 80% owned subsidiary, NuChem. NuChem has limited activity and the non-controlling
interest is not material to the financial statements of the Company. A subsidiary is an entity over which the Company has control,
being the power to govern the financial and operating policies of the investee entity so as to obtain benefits from its activities.
Accounting policies of the subsidiary are consistent with the Company's accounting policies. All intra-group transactions, balances,
revenue and expenses are eliminated on consolidation.



| | (b) | Foreign currency translation:
| | --- | -----------------------------



Foreign currency transactions
are translated into Canadian dollars at rates prevailing on the transaction dates. At the end of each reporting period, monetary
assets and liabilities denominated in foreign currencies are translated into Canadian dollars at the rates in effect at that date.
Gains or losses resulting from the translation to Canadian dollars are presented in the statement of loss and comprehensive loss
for the year within general and administrative expenses.



| | (c) | Derecognition of financial assets
                                         and liabilities:
| | --- | -------------------------------------------------------------------------------------------



A financial asset is derecognized
when the right to receive cash flows from the asset have expired or when the Company has transferred its rights to receive cash
flows from the asset.



A financial liability is derecognized
when its contractual obligations are discharged, cancelled or expire.



| | (d) | Financial assets and liabilities:
| | --- | ---------------------------------



Financial assets within the scope
of IAS 39, Financial Instruments - Recognition and Measurement ("IAS 39"), are classified as either financial
assets at fair value through profit or loss, loans and receivables, held-to-maturity investments or available-for-sale financial
assets, as appropriate. When financial assets are recognized initially, they are measured at fair value, plus, in the case of
financial assets not at fair value through profit or loss, directly attributable transaction costs. The Company determines the
classification of its financial assets at initial recognition and, where allowed and appropriate, re-evaluates this designation
at each financial year end.



F-10







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



The Company's financial instruments
are comprised of the following:



|Financial assets          |  | Classification        |  | Measurement   
|------------------------- |  | --------------------- |  | --------------
|                          |  |                       |  |               
|Cash and cash equivalents |  | Loans and receivables |  | Amortized cost



|Financial liabilities                                               |  | Classification    |  | Measurement   
|------------------------------------------------------------------- |  | ----------------- |  | --------------
|                                                                    |  |                   |  |               
|Accounts payable, accrued liabilities  and promissory notes payable |  | Other liabilities |  | Amortized cost



The Company considers unrestricted
cash on hand and term deposits and guaranteed investment certificates held by Canadian Schedule A banks with original maturities
of three months or less as cash and cash equivalents.



Fair value:



Fair value is the price that
would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the
measurement date. The fair value hierarchy establishes three levels to classify the inputs to valuation techniques used to measure
fair value.



| | · | Level
                                         1 - inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities;
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------



| | · | Level
                                         2 - inputs are quoted prices in markets that are not active, quoted prices for similar
                                         assets or liabilities in active markets, inputs other than quoted prices that are observable
                                         for the asset or liability, or inputs that are derived principally from or corroborated
                                         by observable market data or other means; and
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Level
                                         3 - inputs are unobservable (supported by little or no market activity). The fair value
                                         hierarchy gives the highest priority to Level 1 inputs and the lowest priority to Level
                                         3 inputs.
| | - | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



The Company's financial assets
as at May 31, 2013 and 2012 which include cash and cash equivalents are classified as a Level 1 measurement.



F-11







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (e) | Equipment:
| | --- | ----------



Equipment is measured at cost
less accumulated depreciation and accumulated impairment losses. Cost includes expenditures that are directly attributable to
the acquisition of the asset. The Company records depreciation at rates that charge operations with the cost of the assets over
their estimated useful lives on a straight-line basis as follows:



|Furniture and equipment | 3 - 5 years
|----------------------- | -----------



The assets' residual value, useful
life and methods of depreciation are reviewed at each reporting period and adjusted prospectively if appropriate.



| | (f) | Research and development:
| | --- | -------------------------



Expenditures on research activities,
undertaken with the prospect of gaining new scientific or technical knowledge and understanding, are recognized in profit or loss
as incurred.



Development activities involve
a plan or design for the production of new or substantially improved products or processes. Development expenditures are capitalized
only if development costs can be measured reliably, the product or process is technically and commercially feasible, future economic
benefits are probable, and the Company intends to and has sufficient resources to complete development and to use or sell the
asset. The expenditures capitalized would include the cost of materials, direct labour, overhead costs that are directly attributable
to preparing the asset for its intended use, and borrowing costs on qualifying assets. Other development expenditures which do
not meet the criteria for capitalization are recognized in profit or loss as incurred.



Capitalized development costs
are recognized at cost less accumulated amortization and accumulated impairment losses.



The Company has not capitalized
any development costs to date.



F-12







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (g) | Investment tax credits:
| | --- | -----------------------



Research and development investment
tax credits, which are earned as a result of incurring qualifying research and development expenditures, are recorded as a reduction
of the related expense or cost of the asset acquired when there is reasonable assurance that they will be realized.



The Company's claim for scientific
research and experimental development ("SR&ED") deductions and related investment tax credits for income tax purposes
are based on management's interpretation of the applicable legislation in the Income Tax Act (Canada). These amounts are subject
to review and acceptance by the Canada Revenue Agency or the Ontario Ministry of Finance prior to collection.



| | (h) | Employee benefits:
| | --- | ------------------



| | (i) | Short-term employee benefits:
| | --- | -----------------------------



Short-term employee benefit obligations
are measured on an undiscounted basis and are expensed as the related service is provided.



A liability is recognized for
the amount expected to be paid in short-term cash bonuses if the Company expects to pay these amounts as approved by the Board
of Directors as a result of past services provided by the employee and the obligation can be estimated reliably.



F-13







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (ii) | Stock-based compensation:
| | ---- | -------------------------



The Company has a stock-based
compensation plan (the "Plan") available to officers, directors, employees and consultants with grants under the Plan
approved by the Company's Board of Directors. Under the Plan, the exercise price of each option equals the closing trading price
of the Company's stock on the day prior to the grant. Vesting is provided for at the discretion of the Board of Directors and
the expiration of options is to be no greater than 10 years from the date of grant.



Details regarding the determination
of the fair value of equity settled share-based transactions are set out in note 10.



The Company uses the fair value
based method of accounting for employee awards granted under the Plan. The Company calculates the fair value of each stock option
grant using the Black-Scholes option pricing model at the grant date. The stock-based compensation cost of the options is recognized
as stock-based compensation expense over the relevant vesting period of the stock options using an estimate of the number of options
that will eventually vest.



Stock options awarded to non-employees
are accounted for at the fair value of the goods received or the services rendered. The fair value is measured at the date the
Company obtains the goods or the date the counterparty renders the service. If the fair value of the goods or services cannot
be reliably measured, the fair value of the options granted will be used.



The Company has an alternate
compensation plan that provides directors and senior management with the option of receiving director's fees, salary, bonuses
or other remuneration ("Remuneration") in common shares rather than cash. Under the plan, the participant receives an
allotment from treasury of such number of shares as will be equivalent to the cash value of the Remuneration determined by dividing
the Remuneration by the weighted average closing common share price for the five trading days prior to payment date (the "5-day
VWAP"). The issue price of the shares is the 5-day VWAP. There are currently no shares allotted for issuance under this plan.



F-14







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



The Company has a deferred
share unit (“DSU”) plan that provides directors the option of receiving payment for their services in the form of
share units rather than common shares or cash. Officers may also receive compensation under the plan as determined by the Board
of Directors. Share units entitle the director to elect to receive, on termination of his or her services with the Company, an
equivalent number of common shares, or the cash equivalent of the market value of the common shares at that future date. On November
29, 2012, shareholders of Lorus voted in favour of certain amendments to the DSU plan of Lorus which included providing Lorus
with the ability to issue shares of Lorus from treasury in order to satisfy current and future liabilities under the DSU plan.
The plan gives the holder of the DSU’s the option between settlement in cash or shares of Lorus and the Board of Directors
of Lorus has the final determination as to the method of settlement. It is currently the intention of the Board of Directors to
comply with the wishes of the holder in terms of settlement method. It is also anticipated that the settlement method of the currently
outstanding DSU’s will be in the form of cash and as such the DSU plan has been treated as a cash settled liability.



For units issued under this
plan, the Company records an expense and a liability equal to the market value of the shares issued. The accumulated liability
is adjusted for market fluctuations on a quarterly basis.



As at May 31, 2013, 780,000
deferred share units have been issued and are outstanding (May 31, 2012 – 780,000).



| | (i) | Loss per share:
| | --- | ---------------



Basic loss per share is computed
by dividing the net loss available to common shareholders by the weighted average number of shares outstanding during the year.
Diluted loss per share is computed similar to basic loss per share except that the weighted average shares outstanding is increased
to include additional shares for the assumed exercise of stock options and warrants, if dilutive. The number of additional shares
is calculated by assuming that outstanding stock options and warrants were exercised and that the proceeds from such exercises
were used to acquire common stock at the average market price during the year. The inclusion of the Company's stock options and
warrants in the computation of diluted loss per share has an anti-dilutive effect on the loss per share and, therefore, they have
been excluded from the calculation of diluted loss per share.



F-15







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (j) | Income taxes:
| | --- | -------------



Deferred tax is recognized in
respect of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the
amounts used for taxation purposes.



Deferred tax assets and liabilities
are offset if there is a legally enforceable right to offset current tax liabilities and assets, and they relate to income taxes
levied by the same tax authority on the same taxable entity.



Deferred tax is measured at the
tax rates that are expected to be applied to temporary differences when they reverse, based on the laws that have been enacted
or substantively enacted by the reporting date. A deferred tax asset is recognized for unused tax losses, tax credits and deductible
temporary differences, to the extent that it is probable that future taxable profits will be available against which they can
be utilized.



| | (k) | Provisions:
| | --- | -----------



A provision is recognized if,
as a result of a past event, the Company has a present legal or constructive obligation that can be estimated reliably, and it
is probable that an outflow of economic benefits will be required to settle the obligation. Provisions are determined by discounting
the expected future cash flows at a pre-tax rate that reflects current market assessments of the time value of money and the risks
specific to the liability. The unwinding of the discount is recognized as a financial cost.



Employee entitlements to annual
leave are recognized as the employee earns them. A provision, stated at current cost, is made for the estimated liability at the
end of each reporting period.



The Company has recorded a provision
as related to an indemnification as described in note 14.



F-16







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (l) | Finance income and finance costs:
| | --- | ---------------------------------



Finance income comprises interest
income on funds invested. Interest income is recognized as it accrues in profit or loss using the effective interest method.



Finance costs comprise interest
expense on borrowings and are recognized in profit or loss using the effective interest method.



| | (m) | Recent accounting pronouncements:
| | --- | ---------------------------------



| | (i) | IAS 1, Presentation of Financial
                                         Statements("IAS 1"):
| | --- | ----------------------------------------------------------------------------------------------



In June 2011, the IASB issued
IAS 1. This amendment retains the "one or two statement" approach to presenting the statements of income and comprehensive
income at the option of the entity and only revises the way other comprehensive income is presented. This new standard is effective
for the Company's interim and annual consolidated financial statements commencing June 1, 2013. The Company is assessing the impact
of this new standard on its consolidated financial statements.



| | (ii) | IFRS 9, Financial Instruments("IFRS 9"):
| | ---- | ----------------------------------------



In October 2010, the IASB issued
IFRS 9, which replaces IAS 39, Financial Instruments - Recognition and Measurement and establishes principles for
the financial reporting of financial assets and financial liabilities that will present relevant and useful information to users
of financial statements for their assessment of the amounts, timing and uncertainty of an entity's future cash flows. This new
standard is effective for the Company's interim and annual consolidated financial statements commencing June 1, 2015. The
Company is assessing the impact of this new standard on its consolidated financial statements.



F-17







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            





| | 3. | Significant accounting policies (continued):
| | -- | --------------------------------------------



| | (iii) | IFRS 10, Consolidated Financial
                                         Statements ("IFRS 10"):
| | ----- | ------------------------------------------------------------------------------------------------



This amendment establishes a
single control that applies to all entities. These changes will require management to exercise significant judgment to determine
which entities are controlled, and therefore are required to be consolidated by a parent, compared with the former requirements.
The amendment becomes effective for annual periods beginning on or after January 1, 2013. The Company does not anticipate any
impact on its consolidated financial statements related to the adoption of this new standard.



| | (v) | IFRS 12, Disclosure of Interests
                                         in Other Entities ("IFRS 12"):
| | --- | --------------------------------------------------------------------------------------------------------



In May 2011, the IASB issued
IFRS 12. IFRS 12 establishes new and comprehensive disclosure requirements for all forms of interest in other entities. This new
standard is effective for the Company's interim and annual consolidated financial statements commencing June 1, 2013. The Company
does not expect that this new standard will have any effect on its consolidated financial statements.



| | (vi) | IFRS 13, Fair Value Measurement("IFRS 13"):
| | ---- | -------------------------------------------



In May 2011, the IASB issued
IFRS 13. IFRS 13, replaces the fair value measurement guidance contained in individual IFRSs with a single source of fair
value measurement guidance. This standard establishes a framework for measuring fair value and requires the fair value hierarchy,
to be applied to all fair value measurements, including non-financial assets and liabilities that are measured or based on fair
value in the statement of financial position as well as non-recurring fair value measurements such as assets held-for-sale. Furthermore,
IFRS 13 expands disclosure requirements for fair value measurements to provide information that enables financial statement users
to assess the methods and inputs used to develop fair value measurements and, for recurring fair value measurements that use significant
unobservable inputs (Level 3), the effect of the measurements on profit or loss or other comprehensive income. This new standard
is effective for the Company's interim and annual consolidated financial statements commencing June 1, 2013. The Company
is assessing the impact of this new standard on its consolidated financial statements.



F-18







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 4. | Capital disclosures:
| | -- | --------------------



The Company's objectives when
managing capital are to:



| | · | Maintain
                                         its ability to continue as a going concern in order to provide returns to shareholders
                                         and benefits to other stakeholders;
| | - | ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Maintain
                                         a flexible capital structure which optimizes the cost of capital at acceptable risk;
                                         and
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | Ensure
                                         sufficient cash resources to fund its research and development activity, to pursue partnership
                                         and collaboration opportunities and to maintain ongoing operations.
| | - | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



The capital structure of the
Company consists of equity comprised of share capital, share purchase warrants, stock options, contributed surplus and deficit.
The Company manages its capital structure and makes adjustments to it in light of economic conditions. The Company, upon approval
from its Board of Directors, will balance its overall capital structure through new share issuances, acquiring or disposing of
assets, adjusting the amount of cash balances or by undertaking other activities as deemed appropriate under the specific circumstances.



Pursuant to the commitment letter
(described in note 7) provided by Mr. Herbert Abramson (“Mr. Abramson”) a director of the Company and majority shareholder,
the Company issued a grid promissory note to Mr. Abramson that allowed Lorus to borrow funds of up to $1.8 million. The funds
could be borrowed at a rate of up to $300 thousand per month, incurred interest at a rate of 10% per year and were due and payable
on November 28, 2012. As at May 31, 2012 the Company had borrowed $900 thousand under this promissory note.



As at May 31, 2013 there were
no promissory notes outstanding. Subsequent to the year end (described in note 17) the Company issued additional promissory notes.



The Company is not subject to
externally imposed capital requirements, and the Company's overall strategy with respect to capital risk management remains unchanged
from the year ended May 31, 2012.



| | (a) | Cash and cash equivalents:
| | --- | --------------------------



Cash and cash equivalents consists
of cash of $144 thousand (May 31, 2012 - $76 thousand) and funds deposited into high interest savings accounts totalling
$509 thousand (May 31, 2012 - $nil). The current interest rate earned on these deposits is 1.25% (May 31, 2012 - nil).



F-19







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 4. | Capital disclosures (cont’d):
| | -- | -----------------------------



At May 31, 2012, the Company
had received $244 thousand in deposits related to subscription agreements for the Private Placement (note 9(b)(i)). The Company
recorded a liability related to these funds at May 31, 2012 and on June 8, 2012; the Company reversed the liability with the credit
to share capital when the shares were issued.



| | 5. | Equipment:
| | -- | ----------



|                        |  |      |       |  | Accumulated  |   |       | Net book | 
|----------------------- |  | ---- | ----- |  | ------------ | - | ----- | -------- | 
|May 31, 2013            |  | Cost |       |  | depreciation |   |       | value    | 
|                        |  |      |       |  |              |   |       |          | 
|Furniture and equipment |  | $    | 2,914 |  |              | $ | 2,897 |          | 



|                        |  |      |       |  | Accumulated  |   |       | Net book | 
|----------------------- |  | ---- | ----- |  | ------------ | - | ----- | -------- | 
|May 31, 2012            |  | Cost |       |  | depreciation |   |       | value    | 
|                        |  |      |       |  |              |   |       |          | 
|Furniture and equipment |  | $    | 2,914 |  |              | $ | 2,859 |          | 



| | 6. | Research and development programs:
| | -- | ----------------------------------



The Company has product candidates
in two classes of anticancer therapies:



| | · | small
                                         molecule therapies based on anti-proliferative and anti-metastatic properties that act
                                         at novel cancer specific targets;
| | - | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | · | immunotherapy,
                                         based on stimulating anticancer properties of the immune system and by direct tumour
                                         cell killing; and
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (a) | Small molecule program:
| | --- | -----------------------



The Company is developing small
molecule cancer therapies that target solid tumours with indications addressing large cancer markets. The Company's proprietary
group of small molecule compounds includes lead drug LOR-253 for which Phase I clinical trial results were announced in July 2013
and LOR-500 program, which is in the pre-clinical stage of development.



F-20







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 6. | Research and development programs
                                         (continued):
| | -- | ---------------------------------------------------------------------------------------



| | (b) | Immunotherapy:
| | --- | --------------



The Company's immunotherapy product
candidate is Interleukin-17E ("IL-17E"). IL-17E is a protein-based therapeutic in the pre-clinical stage of development.
On November 27, 2012 the Company announced it had entered into a collaboration agreement with Cancer Research UK for the future
development of immunotherapy IL-17E. Under this collaboration agreement Lorus has committed to provide sufficient quantity of
the drug IL-17E, for no cash consideration, to be used by Cancer Research UK in non-clinical toxicology studies and should those
studies be successful, a Phase I clinical trial. The non-clinical toxicology studies will only be carried out upon the successful
completion of a preclinical program as determined by Cancer Research UK.



Program costs by product class
are as follows:



|                       |  | 2013 |       |  | 2012 |  
|---------------------- |  | ---- | ----- |  | ---- | -
|                       |  |      |       |  |      |  
|Small molecule program |  | $    | 2,701 |  |      | $
|Immunotherapy          |  |      | 425   |  |      |  
|                       |  |      |       |  |      |  
|                       |  | $    | 3,126 |  |      | $



See note 12 for all components
of research and development expenditures.



| | 7. | Promissory notes payable:
| | -- | -------------------------



Pursuant to the commitment letter
(described in note 9(b)(ii)) provided by Mr. Abramson, the Company issued a grid promissory note to Mr. Abramson that allowed
Lorus to borrow funds up to $1.8 million. The funds could be borrowed at a rate of up to $300 thousand per month, incurred interest
at a rate of 10% per year were due and payable in full no later than November 28, 2012.



As at May 31, 2012, the Company
had drawn $900 thousand on this promissory note and in June 2012, the note and all accrued interest was repaid.



Subsequent to the year ended
May 31, 2013, on June 19, 2013 the Company issued additional promissory notes for cash proceeds of $893 thousand which are due
in June 2014 (see note 17).



F-21







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 8. | Financial instruments:
| | -- | ----------------------



| | (a) | Financial instruments:
| | --- | ----------------------



The Company has classified its
financial instruments as follows:



|                                                                                                    |  | May 31, |       |  | May 31, |  
|--------------------------------------------------------------------------------------------------- |  | ------- | ----- |  | ------- | -
|                                                                                                    |  | 2013    |       |  | 2012    |  
|                                                                                                    |  |         |       |  |         |  
|Financial assets:                                                                                   |  |         |       |  |         |  
|Cash and cash equivalents, consisting of high interest  savings account, measured at amortized cost |  | $       | 653   |  |         | $
|                                                                                                    |  |         |       |  |         |  
|Financial liabilities:                                                                              |  |         |       |  |         |  
|Accounts payable, measured at amortized cost                                                        |  |         | 713   |  |         |  
|Accrued liabilities, measured at amortized cost                                                     |  |         | 1,103 |  |         |  
|Promissory notes payable, measured at amortized cost                                                |  |         | –     |  |         |  

| |  | 
| |  | 



At May 31, 2013, there are
no significant differences between the carrying values of these amounts and their estimated market values due to their short-term
nature.



| | (b) | Financial risk management:
| | --- | --------------------------



The Company has exposure to credit
risk, liquidity risk and market risk. The Company's Board of Directors has the overall responsibility for the oversight of these
risks and reviews the Company's policies on an ongoing basis to ensure that these risks are appropriately managed.



| | (i) | Credit risk:
| | --- | ------------



Credit risk is the risk of financial
loss to the Company if a customer, partner or counterparty to a financial instrument fails to meet its contractual obligations,
and arises principally from the Company's cash and cash equivalents. The carrying amount of the financial assets represents the
maximum credit exposure.



F-22







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 8. | Financial instruments (continued):
| | -- | ----------------------------------



The Company manages credit risk
for its cash and cash equivalents by maintaining minimum standards of R1-low or A-low investments and the Company invests only
in highly rated Canadian corporations which are capable of prompt liquidation.



| | (ii) | Liquidity risk:
| | ---- | ---------------



Liquidity risk is the risk that
the Company will not be able to meet its financial obligations as they come due. To the extent that the Company does not believe
it has sufficient liquidity to meet its current obligations, the management and the Board consider securing additional funds through
equity, debt or partnering transactions. The Company manages its liquidity risk by continuously monitoring forecasts and actual
cash flows. All of the Company's financial liabilities are due within the current operating period. Refer to note 2(b) for further
discussion on the Company's ability to continue as a going concern.



| | (iii) | Market risk:
| | ----- | ------------



Market risk is the risk that
changes in market prices, such as interest rates, foreign exchange rates and equity prices, will affect the Company's income or
the value of its financial instruments.



The Company is subject to interest
rate risk on its cash and cash equivalents and short-term investments. The Company does not believe that the results of operations
or cash flows would be affected to any significant degree by a sudden change in market interest rates relative to interest rates
on the investments, owing to the relative short-term nature of the investments. The Company does not have any material interest
bearing liabilities subject to interest rate fluctuations.



Financial instruments potentially
exposing the Company to foreign exchange risk consist principally of accounts payable and accrued liabilities. The Company holds
minimal amounts of U.S. dollar denominated cash, purchasing on an as-needed basis to cover U.S. dollar denominated payments. At
May 31, 2013, U.S. dollar denominated accounts payable and accrued liabilities amounted to $448 thousand (May 31, 2012 - $148
thousand). Assuming all other variables remain constant, a 10% depreciation or appreciation of the Canadian dollar against the
U.S. dollar would result in an increase or decrease in loss for the year and comprehensive loss of $45 thousand (May 31, 2012
- $15 thousand). The Company does not have any forward exchange contracts to hedge this risk.



F-23







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 8. | Financial instruments (continued):
| | -- | ----------------------------------



The Company has issued deferred
share units. The Company has determined that these units represent a cash liability as it is expected that they will be settled
in cash. The value of these units is tied to the share price of the Company and as such is subject to significant variation as
the Company’s stock price is highly volatile. As at May 31, 2013 the Company had issued 780,000 (May 31, 2012 – 780,000)
deferred share units and at May 31, 2013 that represents a cash liability of $172 thousand (May 31, 2012 - $304 thousand). Assuming
all other variables remain constant, a 10% depreciation or appreciation of the Company’s share price would result in an
increase or decrease in loss for the year and comprehensive loss of $17 thousand (May 31, 2012 - $30 thousand).



| | 9. | Share capital:
| | -- | --------------



| | (a) | Continuity of common shares and warrants:
| | --- | -----------------------------------------





|                                    |  | Common shares  |        |  | Warrants |  
|----------------------------------- |  | -------------- | ------ |  | -------- | -
|                                    |  | Number         |        |  | Amount   |  
|                                    |  | (In thousands) |        |  |          |  
|                                    |  |                |        |  |          |  
|Balance, May 31, 2011               |  |                | 15,685 |  |          |  
|Issuance of units (b)(ii)           |  |                | 5,484  |  |          |  
|Warrant repricing (c)(i)            |  |                | –      |  |          |  
|Exercise of warrants (c)(ii)(b)     |  |                | 59     |  |          |  
|Expiry of warrants (c)(ii)(b)       |  |                | –      |  |          |  
|                                    |  |                |        |  |          |  
|Balance, May 31, 2012               |  |                | 21,228 |  |          | $
|Issuance of units (b)(i)            |  |                | 20,625 |  |          |  
|Issuance of finders warrants (b)(i) |  |                | –      |  |          |  
|Exercise of warrants (c)(ii)(a)     |  |                | 398    |  |          |  
|                                    |  |                |        |  |          |  
|Balance, May 31, 2013               |  |                | 42,251 |  |          | $





F-24







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 9. | Share capital (continued):
| | -- | --------------------------



| | (b) | Equity issuances:
| | --- | -----------------



| | (i) | June 2012 Private Placement
| | --- | ---------------------------



On June 8, 2012 Lorus completed
a private placement (the “Private Placement”) of 20,625,000 units at a subscription price of $0.32 per unit, each
unit (“Unit”) consisting of one common share and one common share purchase warrant for gross proceeds to Lorus of
$6,600,000.



Each warrant
is exercisable for a period of 24 months from the date of issuance at an exercise price of $0.45 (the “Warrants”).
If after one year (the “Accelerated Exercise Date”) the closing price of the common shares on the Toronto Stock Exchange
(“TSX”) equals or exceeds $0.90 for twenty consecutive days, then upon the Company sending the holders of Warrants
written notice of such Accelerated Exercise Date and issuing a news release announcing such Accelerated Exercise Date, the Warrants
shall only be exercisable for a period of 30 days following the date on which such written notice is sent to holders of Warrants.



Lorus paid a cash finder’s
fee of $396 thousand based on 6% of the gross proceeds of the Private Placement and issued 1,237,500 finder’s warrants with
an exercise price of $0.32 each. Each finder’s warrant is exercisable into Units consisting of 1,237,500 common shares and
1,237,500 Warrants.



The total costs associated with
the transaction were approximately $617 thousand which includes the $135 thousand which represented the estimated fair value of
the finders warrants issued as part of the Private Placement. Each such finder warrant is exercisable for one Unit at a price
of $0.32 per Unit for a period of 24 months following the closing of the Offering. The Company has allocated the net proceeds
of the Offering to the common shares and the common share purchase warrants based on their estimated relative fair values. Based
on relative fair values, $4.3 million of the net proceeds were allocated to the common shares and $1.7 million to the common share
purchase warrants.



| | (ii) | August 2011 Unit Offering:
| | ---- | --------------------------



On July 22, 2011, the Company
filed a final short-form prospectus in connection with a best efforts offering (the "Offering") of units of the Company
at a price of $0.40 per unit.



F-25







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 9. | Share capital (continued):
| | -- | --------------------------



Each unit consisted of one common
share of Lorus and one common share purchase warrant of Lorus. Each warrant entitles the holder to purchase one common share for
five years after the closing of the Offering at an exercise price of $0.45 per common share (the "Exercise Price").
If on any date (the "Accelerated Exercise Date") the 10-day VWAP of the common shares on the TSX equals or exceeds
200% of the Exercise Price, then upon the Company sending the holders of warrants written notice of such Accelerated Exercise
Date and issuing a news release announcing such Accelerated Exercise Date, the warrants shall only be exercisable for a period
of 30 days following the date on which such written notice is sent to holders of warrants.



In connection with the Offering,
Mr. Abramson, a director of the Company, entered into an irrevocable commitment letter on June 20, 2011, and amended July 11,
2011, to purchase, directly or indirectly, common shares and common share purchase warrants (or as may otherwise be agreed) in
the capital of Lorus having an aggregate subscription price equal to the difference (the "Commitment Amount"), if any,
between: (a) the sum of: (i) the gross proceeds realized by Lorus in the Offering; and (ii) the gross proceeds received by Lorus
in respect of all financings completed by Lorus from the date of the final short-form prospectus to November 30, 2011; and (b)
$4 million.



The Offering closed on August
15, 2011 for total gross proceeds of $2.2 million. In connection with the Offering, Lorus issued 5.484 million common shares and
5.678 million warrants including the broker warrants.



Mr. Abramson purchased 2.4 million
units as part of the Offering.



The total costs associated with
the transaction were approximately $395 thousand, which included the $25 thousand which represented the fair value of the brokers'
services provided as part of the Offering. Each such broker warrant is exercisable for one unit at a price of $0.40 per unit for
a period of 24 months following the closing of the Offering. The Company has allocated the net proceeds of the Offering to the
common shares and the common share purchase warrants based on their estimated relative fair values. Based on relative fair values,
$1.2 million of the net proceeds were allocated to the common shares and $609 thousand to the common share purchase warrants.



F-26









|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 9. | Share capital (continued):
| | -- | --------------------------



| | (c) | Warrants:
| | --- | ---------



| | (i) | Repricing:
| | --- | ----------



On November 29, 2011, shareholders
of the Company (excluding insiders who also held warrants) approved a resolution to amend the exercise price of certain outstanding
warrants from $1.33 to the 5-day volume weighted average trading price on the Toronto Stock Exchange five days prior to approval
plus a 10% premium. The revised warrant exercise price was $0.28. The Company calculated an increased value attributed to the
warrants of $239 thousand related to the amendment. This increase was calculated by taking the Black-Scholes value of the warrants
immediately before the amendment and immediately after the amendment. The increased value was accounted for by an increase in
the warrant equity value and a corresponding reduction in contributed surplus. There were 4.2 million warrants which were amended
and of those 3.6 million were held by Mr. Abramson, a director of the Company.



| | (ii) | Exercises and expiry:
| | ---- | ---------------------



| | (a) | During the year ended May 31, 2013,
                                         398 thousand warrants related to the August 2011 unit offering were exercised for proceeds
                                         of $180 thousand. The fair value related to these warrants was $43 thousand and transferred
                                         from warrants to share capital.
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



(b) The
warrants issued in November 2010 and for which the price was amended in November 2011 ((i) repricing described above), expired
May 8, 2012. A total of 59,384 warrants were exercised for cash proceeds of $17 thousand. The balance of the 4.2 million
warrants expired unexercised, resulting in a transfer of the amount attributed to the expired warrants of $1.253 million to contributed
surplus.



F-27







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 9. | Share capital (continued):
| | -- | --------------------------



| | (d) | Continuity of contributed surplus:
| | --- | ----------------------------------



Contributed surplus is comprised
of the cumulative grant date fair value of expired share purchase warrants and expired stock options as well as the cumulative
amount of previously expensed and unexercised equity settled share-based payment transactions.



|                                             |  | 2013 |        |  | 2012 |  
|-------------------------------------------- |  | ---- | ------ |  | ---- | -
|                                             |  |      |        |  |      |  
|Balance, beginning of year                   |  | $    | 21,186 |  |      | $
|Expiry of warrants (c)                       |  |      | –      |  |      |  
|Warrant repricing (c)                        |  |      | –      |  |      |  
|Forfeiture and cancellation of stock options |  |      | 31     |  |      |  
|                                             |  |      |        |  |      |  
|Balance, end of year                         |  | $    | 21,217 |  |      | $



| | (e) | Continuity of stock options:
| | --- | ----------------------------



|                                             |  | 2013 |       |   | 2012 |  
|-------------------------------------------- |  | ---- | ----- | - | ---- | -
|                                             |  |      |       |   |      |  
|Balance, beginning of year                   |  | $    | 535   |   |      | $
|Stock option expense                         |  |      | 514   |   |      |  
|Cancellation and forfeiture of stock options |  |      | (31   | ) |      |  
|                                             |  |      |       |   |      |  
|Balance, end of year                         |  | $    | 1,018 |   |      | $



| | (f) | Loss per share:
| | --- | ---------------



Loss per common share is calculated
using the weighted average number of common shares outstanding for the year ending May 31, 2013 of 42.251 million and 20.260 million
as of May 31, 2012 calculated as follows:



|                                                    |  | 2013 |        |  | 2012 | 
|--------------------------------------------------- |  | ---- | ------ |  | ---- | 
|                                                    |  |      |        |  |      | 
|Issued common shares, beginning of year             |  |      | 21,228 |  |      | 
|Effect of private placement (note 9(b)(i))          |  |      | 20,625 |  |      | 
|Effect of unit offering (note 9(b)(ii))             |  |      | –      |  |      | 
|Effect of Warrant exercises (note 9(c)(ii)(a))      |  |      | 398    |  |      | 
|                                                    |  |      |        |  |      | 
|Issued weighted average common shares,  end of year |  |      | 42,251 |  |      | 



F-28







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 9. | Share capital (continued):
| | -- | --------------------------



The effect of any potential exercise
of the Company's stock options and warrants outstanding during the year has been excluded from the calculation of diluted loss
per common share as it would be anti-dilutive.



| | (g) | Deferred share unit plan:
| | --- | -------------------------



As at May 31, 2013, 780,000 deferred
share units have been issued (May 31, 2012 – 780,000), with a carrying amount of $172 thousand representing the fair market
value of the units as of May 31, 2013 (May 31, 2012 - $304 thousand) recorded in accrued liabilities.



| | (h) | Employee share purchase plan:
| | --- | -----------------------------



The Company has an employee share
purchase plan ("ESPP"). The purpose of the ESPP is to assist the Company in retaining the services of its employees,
to secure and retain the services of new employees and to provide incentives for such persons to exert maximum efforts for the
success of the Company. The ESPP provides a means by which employees of the Company may purchase common shares of the Company
at a discount through accumulated payroll deductions with each offering having a three-month duration. Participants may authorize
payroll deductions of up to 15% of their base compensation for the purchase of common shares under the ESPP. For the year ended
May 31, 2013, nil (May 31, 2012 – 14,120) common shares have been purchased under the ESPP, and the Company has recognized
an expense of $nil (May 31, 2012 - $1 thousand) related to this plan in these consolidated financial statements. The
ESPP is not active as of May 31, 2013.



F-29







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 10. | Stock-based compensation:
| | --- | -------------------------



Stock option plan:



Under the Company's stock option
plan, options, rights and other entitlements may be granted to directors, officers, employees and consultants of the Company to
purchase up to a maximum of 15% of the total number of outstanding common shares, estimated at 6,338,000 options, rights and other
entitlements as at May 31, 2013. Options are granted at the fair market value of the common shares on the date immediately preceding
the date of the grant. Options vest at various rates (immediate to three years) and have a term of 10 years. Stock option transactions
for the two years ended May 31, 2013 are summarized as follows:



|Option
    numbers are in (000’s)
|---------------------------------



|                               |  | 2013    |       |   | 2012     |  
|------------------------------ |  | ------- | ----- | - | -------- | -
|                               |  |         |       |   | Weighted |  
|                               |  |         |       |   | average  |  
|                               |  |         |       |   | exercise |  
|                               |  | Options |       |   | price    |  
|                               |  |         |       |   |          |  
|Outstanding, beginning of year |  |         | 1,612 |   |          | $
|Granted                        |  |         | 1,780 |   |          |  
|Forfeited                      |  |         | (33   | ) |          |  
|Cancelled                      |  |         | –     |   |          |  
|                               |  |         |       |   |          |  
|Outstanding, end of year       |  |         | 3,359 |   |          |  



The following table summarizes
information about stock options outstanding at May 31, 2013:



|Option numbers are in (000’s)
|-----------------------------



|                |  | Options outstanding |       |  | Options exercisable | 
|--------------- |  | ------------------- | ----- |  | ------------------- | 
|                |  |                     |       |  | Weighted            | 
|                |  |                     |       |  | average             | 
|                |  |                     |       |  | remaining           | 
|Range of        |  |                     |       |  | contractual         | 
|exercise prices |  | Options             |       |  | life (years)        | 
|                |  |                     |       |  |                     | 
|$0.18 - $  0.22 |  |                     | 1,507 |  |                     | 
|$0.23 - $  0.48 |  |                     | 1,780 |  |                     | 
|$0.49 - $  9.90 |  |                     | 72    |  |                     | 
|                |  |                     |       |  |                     | 
|                |  |                     | 3,359 |  |                     | 



F-30







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 10. | Stock-based compensation (continued):
| | --- | -------------------------------------



The following assumptions
were used in the Black-Scholes option pricing model to determine the fair value of stock options granted during the year:



|                                                                                   |  | 2013 |         |   | 2012 |  
|---------------------------------------------------------------------------------- |  | ---- | ------- | - | ---- | -
|                                                                                   |  |      |         |   |      |  
|Exercise price                                                                     |  | $    | 0.475   |   |      |  
|Grant date share price                                                             |  | $    | 0.475   |   |      |  
|Risk-free interest rate                                                            |  |      | 3.0     | % |      |  
|Expected dividend yield                                                            |  |      | –       |   |      |  
|Expected volatility                                                                |  |      | 135     | % |      |  
|Expected life of options                                                           |  |      | 5 years |   |      |  
|Weighted average fair value of
    options granted or modified during the     year |  | $    | 0.42    |   |      | $



The Company uses historical
data to estimate the expected dividend yield and expected volatility of its common shares in determining the fair value of stock
options. The expected life of the options represents the estimated length of time the options are expected to remain outstanding.



Stock options granted by the
Company during the year ended May 31, 2013 have various vesting schedules. Options granted to directors consisted of 160,000 options
that vested 50% upon issuance and 50% one year later. Options granted to the CEO of 1,050,000 vest 50% after one year and 25%
on each of August 2, 2014 and August 2, 2015. Options granted to certain members of management totaled 325,000 and vest 50% upon
certain performance criteria measured as of May 31, 2013 and 25% May 31, 2014 and 25% on May 31, 2015. Options granted to employees
totaled 245,000 and vest 50% after one year and 25% on each of August 2, 2015 and August 2, 2016.



Stock options granted by the
Company during the year ended May 31, 2012 also have various vesting schedules. Options granted to directors consisted of 221,000
options that vested 50% upon issuance and 50% one year later. Two directors received options that totalled 550,000 options which
vested immediately. Options granted to the Chief Executive Officer ("CEO") of 275,000 vested 50% immediately and 25%
on each of November 29, 2012 and 2013. Options granted to certain members of management totalled 300,000 and vested 50% upon certain
performance criteria measured as of May 31, 2012 and 25% May 31, 2013 and 25% on May 31, 2014. An additional 192,000 options
were granted to these members of management which vest 50% on March 9, 2013, 25% on March 9, 2014 and 25% on March 9, 2015.



Refer to note 12 for a breakdown
of stock option expense by function.



F-31







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 11. | Additional cash flow disclosures:
| | --- | ---------------------------------



Net change in non-cash operating
working capital is summarized as follows:



|                                  |  | 2013 |      |   | 2012 |  
|--------------------------------- |  | ---- | ---- | - | ---- | -
|                                  |  |      |      |   |      |  
|Prepaid expenses and other assets |  | $    | (72  | ) |      | $
|Accounts payable                  |  |      | 391  |   |      |  
|Accrued liabilities               |  |      | (371 | ) |      |  
|                                  |  |      |      |   |      |  
|                                  |  | $    | (52  | ) |      | $



During the year ended May
31, 2013, the Company incurred $6 thousand (2012 - $20 thousand) in interest expense on a $900 thousand promissory note due to
Mr. Abramson. The interest was paid at a rate of 10%.



| | 12. | Other expenses:
| | --- | ---------------



Components of research and development
expenses:



|                          |  | 2013 |       |   | 2012 |  
|------------------------- |  | ---- | ----- | - | ---- | -
|                          |  |      |       |   |      |  
|Program costs (note 6)    |  | $    | 3,126 |   |      | $
|Deferred share unit costs |  |      | (40   | ) |      |  
|Stock-based compensation  |  |      | 198   |   |      |  
|Depreciation of equipment |  |      | 33    |   |      |  
|                          |  |      |       |   |      |  
|                          |  | $    | 3,317 |   |      | $



Components of general and
administrative expenses:



|                                              |  | 2013 |       |   | 2012 |  
|--------------------------------------------- |  | ---- | ----- | - | ---- | -
|                                              |  |      |       |   |      |  
|General and administrative excluding salaries |  | $    | 1,368 |   |      | $
|Salaries                                      |  |      | 675   |   |      |  
|Deferred share unit costs                     |  |      | (92   | ) |      |  
|Stock-based compensation                      |  |      | 316   |   |      |  
|Depreciation of equipment                     |  |      | 5     |   |      |  
|                                              |  |      |       |   |      |  
|                                              |  | $    | 2,272 |   |      | $



F-32







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 13. | Related party transactions:
| | --- | ---------------------------



See also notes 7, 9 and 17 for
related party transactions.



These transactions were in the
normal course of business and have been measured at the exchange amount, which is the amount of consideration established and
agreed to by the related parties.



Compensation of key management
personnel:



Key management personnel are
those persons having authority and responsibility for planning, directing and controlling the Company's activities as a whole.
The Company has determined that key management personnel consists of the members of the Board of Directors along with the officers
of the Company.



Officer compensation:



|                                          |  | 2013 |      |   | 2012 |  
|----------------------------------------- |  | ---- | ---- | - | ---- | -
|                                          |  |      |      |   |      |  
|Salaries and short-term employee benefits |  | $    | 727  |   |      | $
|Deferred share units                      |  |      | (132 | ) |      |  
|Stock-based compensation                  |  |      | 358  |   |      |  
|                                          |  |      |      |   |      |  
|                                          |  | $    | 953  |   |      | $



Director compensation:



|                         |  | 2013 |     |  | 2012 |  
|------------------------ |  | ---- | --- |  | ---- | -
|                         |  |      |     |  |      |  
|Directors' fees          |  | $    | 180 |  |      | $
|Stock-based compensation |  |      | 73  |  |      |  
|                         |  |      |     |  |      |  
|                         |  | $    | 253 |  |      | $



Included in accounts payable
and accrued liabilities is $26 thousand (May 31, 2012 - $160 thousand) due to directors and officers of the Company relating
to directors' fees, and reimbursements for employment expenses. These amounts are unsecured, non-interest bearing and have no
fixed terms of repayment.



F-33







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 14. | Commitments, contingencies and guarantees:
| | --- | ------------------------------------------



| | (a) | Operating lease commitments:
| | --- | ----------------------------



The Company has entered into
operating leases for premises and equipment under which it is obligated to make minimum annual payments as described below:



|                 |  | Less than 1 year |     |  | 1 - 3 years |   |     | 3 - 5 years |  |   | Total | 
|---------------- |  | ---------------- | --- |  | ----------- | - | --- | ----------- |  | - | ----- | 
|                 |  |                  |     |  |             |   |     |             |  |   |       | 
|Operating leases |  | $                | 152 |  |             | $ | 137 |             |  | $ | nil   | 



The Company's current facility
lease expires in March 2015.



| | (b) | Other contractual commitments:
| | --- | ------------------------------



The Company holds a non-exclusive
license from Genentech Inc. to certain patent rights to develop and sub-license a certain polypeptide. The Company does not expect
to make any milestone or royalty payments under this agreement in fiscal years ended May 31, 2014 or 2015, and cannot reasonably
predict when such milestones and royalties will become payable, if at all.



The Company has entered into
various contracts with service providers with respect to the LOR-253 Phase I clinical trial. These contracts could result in future
payment commitments of approximately $1.5 million. Of this amount, $740 thousand has been paid and $253 thousand has been
accrued at May 31, 2013 (2012 - $439 thousand paid and $70 thousand accrued). The payments will be based on services performed
and amounts may be higher or lower based on actual services performed.



On November 27, 2012 the Company
announced it had entered into a collaboration agreement with Cancer Research UK for the future development of immunotherapy IL-17E.
Under this collaboration agreement Lorus has committed to provide sufficient quantity of the drug IL-17E, for no cash consideration,
to be used by Cancer Research UK in pre-clinical toxicology studies and should those studies be successful, a Phase I clinical
trial. It is expected that this will result in costs of approximately $4 million over a two year period. The Company has not yet
entered into any contracts related to the drug manufacturing.



F-34







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 14. | Commitments, contingencies and guarantees (continued):
| | --- | ------------------------------------------------------



| | (c) | Guarantees:
| | --- | -----------



The Company entered into various
contracts, whereby contractors perform certain services for the Company. The Company indemnifies the contractors against costs,
charges and expenses in respect of legal actions or proceedings against the contractors in their capacity of servicing the Company.
The maximum amounts payable from these guarantees cannot be reasonably estimated. Historically, the Company has not made significant
payments related to these guarantees.



The Company indemnifies its directors
and officers against any and all claims or losses reasonably incurred in the performance of their service to the Company to the
extent permitted by law. The Company has acquired and maintains liability insurance for its directors and officers. The fair value
of this indemnification is not determinable.



| | (d) | Indemnification on plan of arrangement:
| | --- | ---------------------------------------



On July 10, 2007, Lorus completed
a plan of arrangement and corporate reorganization whereby the assets and liabilities of Lorus were transferred from one corporate
entity into a new corporate entity which continued to operate as Lorus Therapeutics Inc. Under the arrangement, the Company agreed
to indemnify the old entity and its directors, officers and employees from and against all damages, losses, expenses, other third
party costs and legal expenses, to which any of them may be subject arising out of any matter occurring:



| | (i) | prior to, at or after the effective
                                         time of the arrangement ("Effective Time") and directly or indirectly relating
                                         to any of the assets transferred to the Company pursuant to the arrangement (including
                                         losses for income, sales, excise and other taxes arising in connection with the transfer
                                         of any such asset) or conduct of the business prior to the Effective Time;
| | --- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (ii) | prior to, at or after the Effective
                                         Time as a result of any and all interests, rights, liabilities and other matters relating
                                         to the assets transferred to the Company pursuant to the arrangement; and
| | ---- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



| | (iii) | prior to or at the Effective Time
                                         and directly or indirectly relating to, with certain exceptions, any of the activities
                                         of the old entity or the arrangement.
| | ----- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



The Company recorded a liability
of $75 thousand, which it believes to be a reasonable estimate of the fair value of the obligation for the indemnifications provided
as at May 31, 2013. There have been no claims on this indemnification to date.



F-35







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 15. | Income taxes:
| | --- | -------------



Provision
for income taxes:



Major items causing the Company's
income tax rate to differ from the statutory rate of approximately 26.5% (2012 - 27.4%) are as follows:



|                                                                    |  | 2013 |        |   | 2012 |  
|------------------------------------------------------------------- |  | ---- | ------ | - | ---- | -
|                                                                    |  |      |        |   |      |  
|Loss before income taxes                                            |  | $    | (5,565 | ) |      | $
|Statutory Canadian corporate tax rate                               |  |      | 26.5   | % |      |  
|                                                                    |  |      |        |   |      |  
|Anticipated tax recovery                                            |  | $    | (1,475 | ) |      | $
|Non-deductible stock-based compensation                             |  |      | 138    |   |      |  
|Change in deferred tax benefits deemed not probable to be recovered |  |      | 1,553  |   |      |  
|Change in substantively enacted tax rates                           |  |      | –      |   |      |  
|Other                                                               |  |      | (216   | ) |      |  
|                                                                    |  |      |        |   |      |  
|                                                                    |  | $    | –      |   |      | $



The Company has undeducted
research and development expenditures, totalling $21.6 million that can be carried forward indefinitely. In addition, the
Company has non-capital loss carryforwards of $17.7 million. To the extent that the non-capital loss carryforwards are not used,
they expire as follows:



|2015 |  | $ | 10     | 
|---- |  | - | ------ | 
|2026 |  |   | 11     | 
|2027 |  |   | 4      | 
|2028 |  |   | 4,359  | 
|2029 |  |   | 3,753  | 
|2030 |  |   | 650    | 
|2031 |  |   | 2,908  | 
|2032 |  |   | 2,571  | 
|2033 |  |   | 3,473  | 
|     |  | $ | 17,739 | 



F-36







|Lorus Therapeutics Inc.                                                     
|----------------------------------------------------------------------------
|Notes to Consolidated Financial Statements (continued)                      
|(Tabular amounts in thousands of Canadian dollars, except per share amounts)
|                                                                            
|Years ended May 31, 2013 and 2012                                           
|                                                                            



| | 15. | Income taxes (continued):
| | --- | -------------------------



Deferred tax assets have not
been recognized in respect of the following items:



|                                            |  | 2013 |        |  | 2012 |  
|------------------------------------------- |  | ---- | ------ |  | ---- | -
|                                            |  |      |        |  |      |  
|Net operating losses carried forward        |  | $    | 4,701  |  |      | $
|Research and development expenditures       |  |      | 5,731  |  |      |  
|Fixed assets book over tax depreciation     |  |      | 448    |  |      |  
|Intangible asset                            |  |      | 3,097  |  |      |  
|Ontario harmonization tax credit            |  |      | 287    |  |      |  
|Ontario Research and Development Tax Credit |  |      | 327    |  |      |  
|Cumulative eligible capital                 |  |      | 358    |  |      |  
|Other                                       |  |      | 279    |  |      |  
|                                            |  |      |        |  |      |  
|Unrecognized deferred tax asset             |  | $    | 15,228 |  |      | $



| | 16. | Comparative figures:
| | --- | --------------------



Certain
comparative figures have been reclassified to conform with the financial statement presentation adopted in the current year.



| | 17. | Subsequent event:
| | --- | -----------------



On June 19, 2013 the Company
completed a private placement of units at a price of $1,000 per unit, for aggregate gross proceeds of $893,000. Each Unit consisted
of (i) a $1,000 principal amount of unsecured promissory notes; and (ii) 1,000 common share purchase warrants. The Promissory
Notes bear interest at a rate of 10% per annum, payable monthly and are due June 19, 2014. Each Warrant entitles the holder thereof
to acquire one common share of the Company at a price per common share equal to $0.25 at any time until June 19, 2015. Certain
related parties participated in the transaction including Dr. Aiping Young our President and CEO and two Directors, Dr. Wright
and Dr. Vincent for combined proceeds of $68 thousand. Trapeze Capital Corporation (“Trapeze”) also participated in
the transaction for proceeds of $250 thousand. Mr. Abramson, a director of the Company, is a co-founder, Chairman and portfolio
manager at Trapeze.



F-37







Lorus
Therapeutics Inc.

Condensed
Consolidated Interim Statements of Financial Position

(unaudited)



|(amounts in 000's of Canadian Dollars)                  |  | February 28, 2014 |          |   | May 31, 2013 |  
|------------------------------------------------------- |  | ----------------- | -------- | - | ------------ | -
|ASSETS                                                  |  |                   |          |   |              |  
|Current                                                 |  |                   |          |   |              |  
|Cash and cash equivalents (note 4 (a))                  |  | $                 | 7,230    |   |              | $
|Prepaid expenses and other assets                       |  |                   | 502      |   |              |  
|Total Current Assets                                    |  |                   | 7,732    |   |              |  
|Non-current                                             |  |                   |          |   |              |  
|Equipment                                               |  |                   | 12       |   |              |  
|Total Non-Current Assets                                |  |                   | 12       |   |              |  
|Total Assets                                            |  | $                 | 7,744    |   |              | $
|LIABILITIES                                             |  |                   |          |   |              |  
|Current                                                 |  |                   |          |   |              |  
|Accounts payable                                        |  | $                 | 297      |   |              | $
|Accrued liabilities                                     |  |                   | 1,848    |   |              |  
|Promissory note payable (note 6(b))                     |  |                   | 887      |   |              |  
|Total Current Liabilities                               |  |                   | 3,032    |   |              |  
|                                                        |  |                   |          |   |              |  
|Long-term                                               |  |                   |          |   |              |  
|Loans payable (note 8 (b))                              |  |                   | 150      |   |              |  
|Convertible promissory notes (note 8 (a))               |  |                   | 515      |   |              |  
|Total Long Term Liabilities                             |  |                   | 665      |   |              |  
|                                                        |  |                   |          |   |              |  
|SHAREHOLDERS' EQUITY                                    |  |                   |          |   |              |  
|Share capital (note 6)                                  |  |                   |          |   |              |  
|Common shares                                           |  |                   | 184,387  |   |              |  
|Equity portion of convertible promissory notes (note 8) |  |                   | 88       |   |              |  
|Stock options (note 7)                                  |  |                   | 2,285    |   |              |  
|Contributed surplus                                     |  |                   | 21,307   |   |              |  
|Warrants                                                |  |                   | 2,272    |   |              |  
|Deficit                                                 |  |                   | (206,292 | ) |              |  
|Total Equity                                            |  |                   | 4,047    |   |              |  
|Total Liabilities and Equity                            |  | $                 | 7,744    |   |              | $



See
accompanying notes to the condensed consolidated interim financial statements (unaudited)

Commitments,
contingencies and guarantees (Note 12)

Subsequent
events (Note 14)



F-38







Lorus
Therapeutics Inc.

Condensed
Consolidated Interim Statements of Loss and Comprehensive Loss

(unaudited)







|                                                                                                                                                    |  | Three             |        |   | Three         |   |        | Nine              |  |   | Nine          |  
|--------------------------------------------------------------------------------------------------------------------------------------------------- |  | ----------------- | ------ | - | ------------- | - | ------ | ----------------- |  | - | ------------- | -
|                                                                                                                                                    |  | months ended      |        |   | months ended  |   |        | months ended      |  |   | months ended  |  
|(amounts in 000's of Canadian
    Dollars except for per common share data)                                                                         |  | Feb.
    28, 2014 |        |   | Feb. 28, 2013 |   |        | Feb.
    28, 2014 |  |   | Feb. 28, 2013 |  
|REVENUE                                                                                                                                             |  | $                 | -      |   |               | $ | -      |                   |  | $ | -             |  
|                                                                                                                                                    |  |                   |        |   |               |   |        |                   |  |   |               |  
|EXPENSES                                                                                                                                            |  |                   |        |   |               |   |        |                   |  |   |               |  
|Research and development  (notes 10 and 11)                                                                                                         |  |                   | 597    |   |               |   | 889    |                   |  |   | 2,003         |  
|General and administrative (note
    10)                                                                                                            |  |                   | 1,771  |   |               |   | 491    |                   |  |   | 4,160         |  
|Operating expenses                                                                                                                                  |  |                   | 2,368  |   |               |   | 1,380  |                   |  |   | 6,163         |  
|Finance expense                                                                                                                                     |  |                   | 78     |   |               |   | -      |                   |  |   | 184           |  
|Finance income                                                                                                                                      |  |                   | (13    | ) |               |   | (9     | )                 |  |   | (15           | )
|Net financing
    expense (income)                                                                                                                  |  |                   | 65     |   |               |   | (9     | )                 |  |   | 169           |  
|Net loss and
    total comprehensive loss for the period                                                                                            |  |                   | 2,433  |   |               |   | 1,371  |                   |  |   | 6,332         |  
|Basic and diluted
    loss per common share                                                                                                         |  | $                 | 0.04   |   |               | $ | 0.03   |                   |  | $ | 0.13          |  
|                                                                                                                                                    |  |                   |        |   |               |   |        |                   |  |   |               |  
|Weighted
    average number of common shares outstanding used in the calculation of basic and diluted loss per common share (000's) (note
    6(f)) |  |                   | 61,271 |   |               |   | 42,251 |                   |  |   | 49,085        |  



See
accompanying notes to the condensed consolidated interim financial statements (unaudited)



F-39







Lorus
Therapeutics Inc.

Condensed
Consolidated Interim Statement of Changes in Equity

(unaudited)



|(amounts in 000's of Canadian Dollars)             |  | Share
Capital |         |  | Stock
Options |   |       | Warrants |  |   | Contributed
Surplus |   |  | Equity Portion
of Convertible
Debt |        |  | Deficit |   |    | Total | 
|-------------------------------------------------- |  | ------------- | ------- |  | ------------- | - | ----- | -------- |  | - | ------------------- | - |  | ---------------------------------- | ------ |  | ------- | - | -- | ----- | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Balance, June 1, 2013                              |  | $             | 174,522 |  |               | $ | 1,018 |          |  | $ | 2,421               |   |  | $                                  | 21,217 |  |         | $ | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Public equity offering (note 6(a))                 |  |               | 6,927   |  |               |   |       |          |  |   | 350                 |   |  |                                    |        |  |         |   |    |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Issuance of warrants(note 6(b))                    |  |               | -       |  |               |   | -     |          |  |   | 75                  |   |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Warrant and option exercises (notes 6(c) and 6(e)) |  |               | 2,938   |  |               |   | (20   | )        |  |   | (549                | ) |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Stock-based compensation (note 7)                  |  |               | -       |  |               |   | 1,352 |          |  |   | -                   |   |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Issuance of convertible notes (note 8(a))          |  |               | -       |  |               |   | -     |          |  |   | -                   |   |  |                                    | -      |  |         |   | 88 |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Expiry of stock options                            |  |               | -       |  |               |   | (65   | )        |  |   | -                   |   |  |                                    | 65     |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Expiry of broker warrants                          |  |               |         |  |               |   |       |          |  |   | (25                 | ) |  |                                    | 25     |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Net loss                                           |  |               | -       |  |               |   | -     |          |  |   | -                   |   |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Balance, February 28, 2014                         |  | $             | 184,387 |  |               | $ | 2,285 |          |  | $ | 2,272               |   |  | $                                  | 21,307 |  |         | $ | 88 |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Balance, June 1, 2012                              |  | $             | 170,036 |  |               | $ | 535   |          |  | $ | 609                 |   |  | $                                  | 21,186 |  |         | $ | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Issuance of units                                  |  |               | 4,263   |  |               |   | -     |          |  |   | 1,855               |   |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Warrant exercises                                  |  |               | 223     |  |               |   | -     |          |  |   | (43                 | ) |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Stock-based compensation (note 7)                  |  |               | -       |  |               |   | 380   |          |  |   | -                   |   |  |                                    | -      |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Expiry of stock options                            |  |               | -       |  |               |   | (31   | )        |  |   | -                   |   |  |                                    | 31     |  |         |   | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Net loss                                           |  |               | -       |  |               |   | -     |          |  |   | -                   |   |  |                                    | -      |  |         | $ | -  |       | 
|                                                   |  |               |         |  |               |   |       |          |  |   |                     |   |  |                                    |        |  |         |   |    |       | 
|Balance, February 28, 2013                         |  | $             | 174,522 |  |               | $ | 884   |          |  | $ | 2,421               |   |  | $                                  | 21,217 |  |         | $ | -  |       | 



F-40







Lorus
Therapeutics Inc.

Condensed
Consolidated Interim Statements of Cash Flows

(unaudited)



|                                                                   |  | Three         |        |   | Three         |   |        | Nine          |  |   | Nine          |  
|------------------------------------------------------------------ |  | ------------- | ------ | - | ------------- | - | ------ | ------------- |  | - | ------------- | -
|                                                                   |  | months ended  |        |   | months ended  |   |        | months ended  |  |   | months ended  |  
|(amounts in 000's of Canadian Dollars)                             |  | Feb. 28, 2014 |        |   | Feb. 28, 2013 |   |        | Feb. 28, 2014 |  |   | Feb. 28, 2013 |  
|Cash flows from operating  activities:                             |  |               |        |   |               |   |        |               |  |   |               |  
|Net loss for the period                                            |  | $             | (2,433 | ) |               | $ | (1,371 | )             |  | $ | (6,332        | )
|Items not involving cash and other adjustments:                    |  |               |        |   |               |   |        |               |  |   |               |  
|Stock-based compensation                                           |  |               | 349    |   |               |   | 140    |               |  |   | 1,352         |  
|Depreciation of equipment                                          |  |               | 5      |   |               |   | 9      |               |  |   | 13            |  
|Finance income                                                     |  |               | (13    | ) |               |   | (9     | )             |  |   | (15           | )
|Accretion expense                                                  |  |               | 36     |   |               |   | -      |               |  |   | 87            |  
|Finance expense                                                    |  |               | 42     |   |               |   | -      |               |  |   | 97            |  
|Other                                                              |  |               | (2     | ) |               |   | -      |               |  |   | (1            | )
|Change in non-cash operating working capital (note 9)              |  |               | (175   | ) |               |   | (42    | )             |  |   | 192           |  
|Cash used in operating activities                                  |  |               | (2,191 | ) |               |   | (1,273 | )             |  |   | (4,607        | )
|Cash flows from financing activities:                              |  |               |        |   |               |   |        |               |  |   |               |  
|Issuance of common shares and warrants, net of issuance costs      |  |               | 7,277  |   |               |   | -      |               |  |   | 7,277         |  
|Exercise of warrants and options                                   |  |               | 440    |   |               |   | -      |               |  |   | 2,369         |  
|Issuance of loans, promissory notes and warrants                   |  |               | -      |   |               |   | -      |               |  |   | 1,068         |  
|Repayment of promissory notes                                      |  |               | -      |   |               |   | -      |               |  |   | -             |  
|Issuance of convertible notes                                      |  |               | -      |   |               |   | -      |               |  |   | 600           |  
|Issuance costs                                                     |  |               | -      |   |               |   | -      |               |  |   | (40           | )
|Interest on promissory notes                                       |  |               | (42    | ) |               |   | -      |               |  |   | (97           | )
|Cash provided by financing activities                              |  |               | 7,675  |   |               |   | -      |               |  |   | 11,177        |  
|Cash flows from investing activities:                              |  |               |        |   |               |   |        |               |  |   |               |  
|Purchase of fixed assets                                           |  |               | (5     | ) |               |   | -      |               |  |   | (8            | )
|Interest income                                                    |  |               | 13     |   |               |   | 9      |               |  |   | 15            |  
|Cash (used in) provided by investing activities                    |  |               | 8      |   |               |   | 9      |               |  |   | 7             |  
|Increase (decrease) in cash and cash equivalents during the period |  |               | 5,492  |   |               |   | (1,264 | )             |  |   | 6,577         |  
|Cash and cash equivalents, beginning of period                     |  |               | 1,738  |   |               |   | 2,816  |               |  |   | 653           |  
|Cash and cash equivalents, end of period                           |  | $             | 7,230  |   |               | $ | 1,552  |               |  | $ | 7,230         |  



See
accompanying notes to the condensed consolidated interim financial statements (unaudited)



F-41







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



| | 1. | Reporting
                                         Entity
| | -- | ---------------------------------------------------------



Lorus
Therapeutics Inc. (“Lorus” or the “Company”) is a biopharmaceutical company focused on the discovery,
research and development of novel anticancer therapies with a high safety profile. Lorus has worked to establish a diverse anticancer
product pipeline, with products in various stages of development ranging from discovery and pre-clinical to clinical stage development.
The Company’s shares are listed on the Toronto Stock Exchange. The head office, principal address and records of the Company
are located at 2 Meridian Road, Toronto, Ontario, Canada, M9W 4Z7.



| | 2. | Basis
                                         of presentation
| | -- | --------------------------------------------------------------



(a)
Statement of Compliance

These
unaudited condensed consolidated interim financial statements of the Company and its subsidiary as at February 28, 2014 were prepared
in accordance with International Financial Reporting Standards (“IFRS”) and International Accounting Standard (“IAS”)
34, Interim Financial Reportingas issued by the International Accounting Standards Board (“IASB”) and does
not include all of the information required for full annual financial statements. These unaudited condensed consolidated interim
financial statements should be read in conjunction with the Company’s audited annual consolidated financial statements and
accompanying notes.



The
unaudited condensed consolidated interim financial statements of the Company were reviewed by the Audit Committee and approved
and authorized for issue by the Board of Directors on April 10, 2014.



(b)
Basis of measurement

These
unaudited condensed consolidated interim financial statements have been prepared in accordance with IFRS accounting principles
applicable to a going concern using the historical cost basis except for deferred share units which are measured at fair value.



(c)
Functional and presentation currency

The
functional and presentation currency of the Company and its Canadian subsidiary Nuchem Pharmaceuticals Inc. is the Canadian dollar
(“$”).



(d)
Significant accounting judgments, estimates and assumptions

The
preparation of these unaudited condensed consolidated interim financial statements in accordance with IFRS requires management
to make judgments, estimates and assumptions that affect the application of accounting policies and reported amounts of assets
and liabilities at the date of the unaudited condensed consolidated interim financial statements and reported amounts of revenues
and expenses during the reporting period. Actual outcomes could differ from these estimates. The unaudited condensed consolidated
interim financial statements include estimates, which, by their nature, are uncertain. The impacts of such estimates are pervasive
throughout the unaudited condensed consolidated interim financial statements, and may require accounting adjustments based on
future occurrences.



The
estimates and underlying assumptions are reviewed on a regular basis. Revisions to accounting estimates are recognized in the
period in which the estimate is revised and in any future periods affected.



The
key assumptions concerning the future, and other key sources of estimation uncertainty as of the date of the statement of financial
position that have a significant risk of causing material adjustment to the carrying amounts of assets and liabilities within
the next fiscal year arise in connection with the valuation of contingent liabilities. Significant estimates also take place in
connection with the valuation of compound instruments, valuation of share-based compensation, share purchase warrants and finders’
warrants.



| | 3. | Significant
                                         accounting policies
| | -- | ------------------------------------------------------------------------



The
accompanying unaudited condensed consolidated interim financial statements are prepared in accordance with IFRS and follow the
same accounting policies and methods of application as the audited consolidated financial statements of the Company for the year
ending May 31, 2013. They do not include all of the information and disclosures required by IFRS for annual financial statements.
In the opinion of management, all adjustments considered necessary for fair presentation have been included in these unaudited
condensed consolidated interim financial statements. Operating results for the three and nine month periods ended February 28,
2014 are not necessarily indicative of the results that may be expected for the full year ended May 31, 2014. For further information,
see the Company’s audited consolidated financial statements including notes thereto for the year ended May 31, 2013.



F-42







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



Standards
and Interpretations Adopted in Fiscal 2014

On
June 1, 2013, we adopted the following standards and amendments to existing standards:

IFRS
10, Consolidated Financial Statements, (“IFRS 10”) replaces consolidation requirements in IAS 27, consolidated and
Separate Financial Statements, and SIC-12, Consolidation – Special Purpose Entities, and establishes principles for identifying
when an entity controls other entities. The adoption of this standard did not have any impact on the Company’s financial
statements.



IFRS
12, Disclosure of Interests in Other Entities, (“IFRS 12”) establishes comprehensive disclosure requirements for all
forms of interests in other entities, including joint arrangements, associates, and special purpose vehicles. The adoption of
this standard did not have any impact on the Company’s financial statements.



IFRS
13, Fair Value Measurement, provides a single source of fair value measurement and disclosure requirements in IFRS. The adoption
of this standard did not have a material impact on the Company’s financial statements.



Amendments
to IAS 1, Presentation of Financial Statements, to require entities to group items within other comprehensive income that may
be reclassified to net income. The adoption of this standard did not have a material impact on the Company’s financial statements.



| | 4. | Capital
                                         disclosures
| | -- | ------------------------------------------------------------



The
Company’s objectives when managing capital are to:





| | · | Maintain
its ability to continue as a going concern;
| | - | ----------------------------------------------------



| | · | Maintain a flexible capital structure which optimizes the cost of capital at acceptable risk; and
| | - | -------------------------------------------------------------------------------------------------



| | · | Ensure sufficient cash resources to fund its research and development activity, to pursue partnership and collaboration opportunities and to maintain ongoing operations.
| | - | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------



The
capital structure of the Company consists of cash and cash equivalents and equity comprised of share capital, share purchase warrants,
stock options, contributed surplus and deficit. The Company manages its capital structure and makes adjustments to it in light
of economic conditions. The Company, upon approval from its Board of Directors, will balance its overall capital structure through
new share issuances, acquiring or disposing of assets, adjusting the amount of cash balances or by undertaking other activities
as deemed appropriate under the specific circumstances.



The
Company is not subject to externally imposed capital requirements.



The
Company’s overall strategy with respect to capital risk management remains unchanged from the year ended May 31, 2013.



| | (a) | Cash
                                         and cash equivalents
| | --- | ------------------------------------------------------------------



As
at February 28, 2014 cash and cash equivalents consists of cash of $960 thousand (May 31, 2013 - $144 thousand) and funds deposited
into High Interest Savings Accounts totaling $6.270 million (May 31, 2013 –$509 thousand). The current interest rate earned
on these deposits is 1.25% (May 31, 2013 – 1.25%)



| | 5. | Financial
                                         instruments
| | -- | --------------------------------------------------------------



(a)
Financial instruments



The
Company has classified its financial instruments as follows:



|                                                                                                                     |  | As
    at             |       |  | As
    at        |  
|-------------------------------------------------------------------------------------------------------------------- |  | --------------------- | ----- |  | ---------------- | -
|                                                                                                                     |  | February
    28, 2014 |       |  | May
    31, 2013 |  
|                                                                                                                     |  |                       |       |  |                  |  
|Financial
    assets                                                                                                 |  |                       |       |  |                  |  
|Cash
    and cash equivalents (consisting of deposits in high interest savings accounts), measured at amortized cost |  | $                     | 7,230 |  |                  | $
|Financial
    liabilities                                                                                            |  |                       |       |  |                  |  
|Accounts
    payable, measured at amortized cost                                                                     |  |                       | 297   |  |                  |  
|                                                                                                                     |  |                       |       |  |                  |  
|Accrued
    liabilities, measured at amortized cost                                                                  |  |                       | 1,848 |  |                  |  
|                                                                                                                     |  |                       |       |  |                  |  
|Promissory
    note payable, measured at amortized cost                                                              |  |                       | 887   |  |                  |  
|                                                                                                                     |  |                       |       |  |                  |  
|Long
    term loans payable, measured at amortized cost                                                              |  |                       | 150   |  |                  |  
|                                                                                                                     |  |                       |       |  |                  |  
|Convertible
    promissory notes, measured at amortized cost                                                         |  |                       | 515   |  |                  |  



F-43







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



At
February 28, 2014, there are no significant differences between the carrying values of these amounts and their estimated market
values.



(b)
Financial risk management



The
Company has exposure to credit risk, liquidity risk and market risk. The Company's Board of Directors has the overall responsibility
for the oversight of these risks and reviews the Company's policies on an ongoing basis to ensure that these risks are appropriately
managed.



(i)
Credit risk



Credit
risk is the risk of financial loss to the Company if a customer, partner or counterparty to a financial instrument fails to meet
its contractual obligations, and arises principally from the Company's cash and cash equivalents. The carrying amount of the financial
assets represents the maximum credit exposure.



The
Company manages credit risk for its cash and cash equivalents by maintaining minimum standards of R1-low or A-low investments
and the Company invests only in highly rated Canadian corporations with debt securities that are traded on active markets and
are capable of prompt liquidation.



(ii)
Liquidity risk



Liquidity
risk is the risk that the Company will not be able to meet its financial obligations as they come due. To the extent that the
Company does not believe it has sufficient liquidity to meet its current obligations, the Board considers securing additional
funds through equity, debt or partnering transactions. The Company manages its liquidity risk by continuously monitoring forecasts
and actual cash flows.



(iii)
Market risk



Market
risk is the risk that changes in market prices, such as interest rates, foreign exchange rates and equity prices will affect the
Company's income or the value of its financial instruments.



The
Company is subject to interest rate risk on its cash and cash equivalents. The Company does not believe that the results of operations
or cash flows would be affected to any significant degree by a sudden change in market interest rates relative to interest rates
on the investments, owing to the relative short-term nature of the investments. The Company does not have any material interest
bearing liabilities subject to interest rate fluctuations.



Financial
instruments potentially exposing the Company to foreign exchange risk consist principally of accounts payable and accrued liabilities.
The Company holds minimal amounts of U.S. dollar denominated cash, purchasing on an as needed basis to cover U.S. dollar denominated
payments. At February 28, 2014, U.S. dollar denominated accounts payable and accrued liabilities amounted to $202 thousand (May
31, 2013 - $448 thousand). Assuming all other variables remain constant, a 10% depreciation or appreciation of the Canadian dollar
against the U.S. dollar would result in an increase or decrease in loss for the year and comprehensive loss of $20 thousand (May
31, 2013 - $45 thousand). The Company does not have any forward exchange contracts to hedge this risk.



The
Company has issued deferred share units. These units represent a cash liability to the Company which fluctuates with the share
price of the Company and as such is subject to significant variation as the Company’s stock price is highly volatile. As
at February 28, 2014 the Company had issued 780,000 (May 31, 2013 – 780,000) deferred share units and at February 28, 2014
that represents a cash liability of $608 thousand (May 31, 2013 - $172 thousand). Assuming all other variables remain constant,
a 10% depreciation or appreciation of the Company’s share price would result in an increase or decrease in loss for the
year and comprehensive loss of $61 thousand (May 31, 2013 - $17 thousand).



The
Company does not invest in equity instruments of other corporations.



F-44







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



| | 6. | Share
                                         capital
| | -- | ------------------------------------------------------



The
Company is authorized to issue an unlimited number of common shares.



Continuity
of common shares and warrants



|                                         |  | Common
    Shares |        |  | Warrants |  
|---------------------------------------- |  | ----------------- | ------ |  | -------- | -
|(amounts
    in 000's)                   |  | Number            |        |  | Amount   |  
|                                         |  |                   |        |  |          |  
|Balance
    at May 31, 2013              |  |                   | 42,251 |  |          | $
|Expiry
    of broker warrants (c)        |  |                   | ─      |  |          |  
|Issuance
    of warrants (b)             |  |                   | ─      |  |          |  
|Balance
    at August 31, 2013           |  |                   | 42,251 |  |          | $
|Warrant
    exercises (c)                |  |                   | 4,445  |  |          |  
|Balance
    at November 30, 2013         |  |                   | 46,696 |  |          | $
|Public
    equity offering (a)           |  |                   | 12,730 |  |          |  
|Exercise
    of overallotment option (a) |  |                   | 1,910  |  |          |  
|Warrant
    exercises (c)                |  |                   | 932    |  |          |  
|Option
    exercises                     |  |                   | 68     |  |          |  
|Balance
    at February 28, 2014         |  |                   | 62,336 |  |          | $



| | (a) | Public
                                         Equity Offering and Overallotment
| | --- | ---------------------------------------------------------------------------------



On
December 10, 2013, we completed a public offering of common shares. Lorus issued a total of 12,730,000 common shares at a price
of $0.55 per common share, for aggregate gross proceeds of $7,001,500 as part of such offering.



The
total costs associated with the transaction were approximately $999 thousand which include a cash commission of $420 thousand
based on 6% of the gross proceeds received as part of the offering, and the issuance of 763,800 broker warrants with an estimated
fair value of $304 thousand. The fair value of these warrants was determined using the Black Scholes model with a 24 month time
to maturity, an assumed volatility of 130% and a risk free interest rate of 1.5%. Each broker warrant is exercisable into one
common share of the Company at a price of $0.55 for a period of twenty four months following closing of the offering.



Mr.
Sheldon Inwentash and his joint actors (“Mr. Inwentash”) a related party of the Company by virtue of exercising control
or direction over more than 10% of the common shares of the Company participated in the Offering and acquired an aggregate of
1,820,000 common shares.



On
January 8, 2014, the underwriters conducting the offering exercised in full their over-allotment option to purchase an additional
1,909,500 common shares of the Company at a price of $0.55 per common share for additional gross proceeds of $1,050,225. The total
costs associated with the exercise of the over-allotment option were approximately $125 thousand based on 6% of the gross proceeds
received as part of the exercise of the over-allotment option, and the issuance of 114,570 broker warrants with an estimated fair
value of $46 thousand using the Black Scholes model with the same assumptions as disclosed above. Each broker warrant is exercisable
into one common share of the Company at a price of $0.55 for a period of twenty four months following closing of over-allotment
option exercise.



| | (b) | Promissory
                                         Notes and Warrants
| | --- | ----------------------------------------------------------------------



In
June 2013 the Company completed a private placement of units (“Units”) at a price of $1,000 per unit, for aggregate
gross proceeds of $918 thousand.



Each
Unit consists of (i) a $1,000 principal amount of unsecured promissory note and (ii) 1,000 common share purchase warrants.
The promissory notes bear interest at a rate of 10% per annum, payable monthly and are due June 19, 2014. Each warrant entitles
the holder thereof to acquire one common share of the Company at a price per common share equal to $0.25 at any time until June
19, 2015.



Certain
related parties participated in the transaction. Directors and officers (including Dr. Aiping Young, Dr. Jim Wright and Dr. Mark
Vincent) acquired an aggregate of $68 thousand of the promissory notes. A company related to a Mr. Abramson, a former director
of the Company acquired $250 thousand of the promissory notes and Mr. Inwentash acquired $100 thousand of the promissory notes.



The
promissory notes contain a liability component and an equity component represented by the warrants to purchase common shares.
The fair value of the liability component was estimated by discounting the future cash flows associated with the debt at a discounted
rate of approximately 19% which represents the estimated borrowing cost to the Company for similar promissory notes with no warrants.
The residual value was allocated to the warrants. Subsequent to initial recognition, the notes are recorded at amortized cost
using the effective interest rate method.



F-45







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



The
Company incurred costs associated with the financing of $23 thousand. These costs are being amortized using the effective interest
rate method over the 12 month life of the notes.



|                                            |  | Nine
    months ended |     |   | Nine
    months ended |  
|------------------------------------------- |  | --------------------- | --- | - | --------------------- | -
|                                            |  | February
    28, 2014 |     |   | February
    28. 2013 |  
|                                            |  |                       |     |   |                       |  
|Promissory
    Notes                        |  | $                     | 918 |   |                       | $
|Less:
    Equity warrant component of notes |  |                       | (75 | ) |                       |  
|Less:
    Issue costs                       |  |                       | (23 | ) |                       |  
|                                            |  |                       | 820 |   |                       |  
|Accretion
    in carrying value of notes    |  |                       | 67  |   |                       |  
|Balance,
    end of period                  |  | $                     | 887 |   |                       | $



| | (c) | Exercise
                                         of Warrants
| | --- | -------------------------------------------------------------



During
the nine month period ended February 28, 2014 5.377 million warrants (February 28, 2013 – 398 thousand) were exercised for
proceeds of $2.35 million (February 28, 2013 – $180 thousand). The carrying amount related to these warrants was $549 thousand
(February 28, 2013 - $43 thousand) and was transferred from warrants to share capital.



Expiry
of Warrants



Broker
warrants with a carrying amount of $25 thousand expired unexercised in August 2013. The impact of the expiry was a reclassification
of the amount from warrants to contributed surplus.



(d)
Continuity of contributed surplus



Contributed
surplus is comprised of the cumulative grant date fair value of expired share purchase warrants and expired stock options as well
as the cumulative amount of previously expensed and unexercised equity settled share-based payment transactions.



|                                   |  | Nine
    months ended |        |  | Nine
    months ended |  
|---------------------------------- |  | --------------------- | ------ |  | --------------------- | -
|                                   |  | February
    28, 2014 |        |  | February
    28, 2013 |  
|                                   |  |                       |        |  |                       |  
|Balance,
    beginning of year     |  | $                     | 21,217 |  |                       | $
|Expiry
    of broker warrants      |  |                       | 25     |  |                       |  
|Expiry
    of vested stock options |  |                       | 65     |  |                       |  
|Balance,
    end of period         |  | $                     | 21,307 |  |                       | $



(e)
Continuity of stock options



|                                   |  | Nine
    months ended |       |   | Nine
    months ended |  
|---------------------------------- |  | --------------------- | ----- | - | --------------------- | -
|                                   |  | February
    28, 2014 |       |   | February
    28, 2013 |  
|Balance,
    beginning of year     |  | $                     | 1,018 |   |                       | $
|Stock
    based compensation       |  |                       | 1,352 |   |                       |  
|Exercise
    of stock options      |  |                       | (20   | ) |                       |  
|Expiry
    of vested stock options |  |                       | (65   | ) |                       |  
|Balance,
    end of period         |  | $                     | 2,285 |   |                       | $



F-46







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



(f)
Loss per share



Loss
per common share is calculated using the weighted average number of common shares outstanding for the three and nine month periods
ending February 28, 2014 calculated as follows:



|                                              |  | Three
    months ended |        |  | Nine
    months ended | 
|--------------------------------------------- |  | ---------------------- | ------ |  | --------------------- | 
|                                              |  | February
    28        |        |  | February
    28       | 
|                                              |  | 2014                   |        |  | 2013                  | 
|                                              |  |                        |        |  |                       | 
|Issued
    common shares, beginning of period |  |                        | 42,251 |  |                       | 
|Effect
    of private placement               |  |                        | —      |  |                       | 
|Effect
    of public offering                 |  |                        | 12,730 |  |                       | 
|Effect
    of overallotment                   |  |                        | 1,273  |  |                       | 
|Effect
    of warrant and option exercises    |  |                        | 5,017  |  |                       | 
|                                              |  |                        | 61,271 |  |                       | 



The
effect of any potential exercise of our stock options and warrants outstanding during the year has been excluded from the calculation
of diluted loss per common share as it would be anti-dilutive.



| | 7. | Stock
                                         options
| | -- | ------------------------------------------------------



(a)
Stock options transactions for the period:



|                                   |  | Nine
    months ended |       |   | Nine
    months ended                   |  
|---------------------------------- |  | --------------------- | ----- | - | --------------------------------------- | -
|                                   |  | February
    28, 2014 |       |   | February
    28, 2013                   |  
|                                   |  | Number
    of Options |       |   | Weighted
    average exercise
    price |  
|                                   |  |                       |       |   |                                         |  
|Outstanding,
    Beginning of year |  |                       | 3,358 |   |                                         | $
|Granted                            |  |                       | 3,358 |   |                                         |  
|Exercised                          |  |                       | (68   | ) |                                         |  
|Expired                            |  |                       | (35   | ) |                                         |  
|Outstanding,
    end of period     |  |                       | 6,613 |   |                                         | $



(b)
Stock options outstanding at February 28, 2014:



|                    |  | Options
    outstanding |       |  | Options
    exercisable | 
|------------------- |  | ----------------------- | ----- |  | ----------------------- | 
|                    |  |                         |       |  | Weighted                | 
|                    |  |                         |       |  | average                 | 
|                    |  |                         |       |  | remaining               | 
|Range
    of        |  | Number                  |       |  | contractual             | 
|exercise
    prices |  | of
    Options          |       |  | life
    (years)        | 
|                    |  |                         |       |  |                         | 
|$
    0.18 - $ 0.22 |  |                         | 1,466 |  |                         | 
|$
    0.23 - $ 0.48 |  |                         | 2,324 |  |                         | 
|$
    0.49 - $ 9.90 |  |                         | 2,823 |  |                         | 
|                    |  |                         |       |  |                         | 
|                    |  |                         | 6,613 |  |                         | 



F-47







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



(c)
Fair value assumptions



The
following assumptions were used in the Black-Scholes option-pricing model to determine the fair value of stock options granted
during the following periods:





|                                                                 |  | Nine
    months ended |                                                  |   | Nine
    months ended |  
|---------------------------------------------------------------- |  | --------------------- | ------------------------------------------------ | - | --------------------- | -
|                                                                 |  | February
    28, 2014 |                                                  |   | February
    28, 2013 |  
|                                                                 |  |                       |                                                  |   |                       |  
|Exercise
    price                                               |  | $                     | 0.29-0.78                                        |   |                       | $
|Grant
    date share price                                       |  | $                     | 0.29-0.78                                        |   |                       | $
|Risk
    free interest rate                                      |  |                       | 1.5                                              | % |                       |  
|Expected
    dividend yield                                      |  |                       | —                                                |   |                       |  
|Expected
    volatility                                          |  |                       | 135                                              | % |                       |  
|Expected
    life of options                                     |  |                       | 5
                                         years |   |                       |  
|Weighted
    average fair value of options granted in the period |  | $                     | 0.53                                             |   |                       | $



Stock
options granted by the Company during the nine months ended February 28, 2014 consisted of 1,663,000 options which vested immediately,
850,000 options that vested 50% upon issuance and 25% on each of the next two anniversaries and 845,000 options which vest 50%,
25% and 25% on each of the next three anniversaries.



Stock
options granted by the Company during the nine months ended February 28, 2013 have various vesting schedules. Options granted
to directors consisted of 160,000 options that vested 50% upon issuance and 50% one year later. Options granted to the former
Chief Operating Officer consisting of 1,050,000 options that vest 50% after one year and 25% on each of August 2, 2014 and August
2, 2015. Options granted to certain employees totaled 325,000 and vested 50% upon certain performance criteria measured as of
May 31, 2013 and 25% on May 31, 2014 and 25% on May 31, 2015. Options granted to employees totaled 245,000 and vest 50% after
one year and 25% on each of August 2, 2014 and August 2, 2015.



Refer
to note 10 for a breakdown of stock option expense by function.



The
Company has reserved up to 9,300,000 common shares for issuance relating to outstanding options, rights and other entitlements
under the stock based compensation plans of the Company as of February 28, 2014.



(d)
Deferred share units



The
Lorus Deferred Share Unit (DSU) plan gives the holder of the DSU’s the option between settlement in cash or shares of Lorus
and the Board of Directors of Lorus has the final determination as to the method of settlement. It is currently the intention
of the Board of Directors to comply with the wishes of the holder in terms of settlement method. It is also anticipated that the
settlement method of the currently outstanding DSU’s will be in the form of cash and as such the liability has been treated
as a cash settled liability.



As
at February 28, 2014, 780,000 deferred share units have been issued (May 31, 2013 – 780,000), with a carrying amount of
$608 thousand representing the fair market value of the units as of February 28, 2014 (May 31, 2013 - $172 thousand) recorded
in accrued liabilities.



| | 8. | Convertible
                                         promissory notes and loans payable
| | -- | ---------------------------------------------------------------------------------------



| | a) | Convertible
                                         promissory notes
| | -- | ---------------------------------------------------------------------



In
September 2013 the Company completed a private placement of convertible promissory notes for aggregate gross proceeds of $600
thousand.



Each
convertible promissory note consists of a $1,000 principal amount of unsecured promissory note convertible into common shares
of the Company at a price per share of $0.30. The promissory notes bear interest at a rate of 10% per annum, payable quarterly
and are due September 26, 2015.



Certain
related parties participated in the transaction. A company related to Mr. Abramson, a former director of Lorus acquired $100 thousand
of the promissory notes, Mr. Inwentash acquired $150 thousand of the promissory notes and Sprott Asset Management which held more
than 10% of the common shares of Lorus and the ability to acquire control of more than 20% of Lorus acquired $112 thousand of
the promissory notes.



The
promissory notes are a compound instrument containing a liability component and an equity component represented by the conversion
feature. The fair value of the liability component was estimated by discounting the future cash flows associated with the debt
at a discounted rate of approximately 19% which represents the estimated borrowing cost to the Company for similar promissory
notes with no warrants. The residual value was allocated to the conversion feature. Subsequent to initial recognition, the notes
will be recorded at amortized cost using the effective interest rate method.



F-48







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



The
Company incurred costs associated with the financing of $17 thousand. These costs will be amortized using the effective interest
rate method over the 24 month life of the notes.







|                                         |  | Nine
    months ended |     |   | Nine
    months ended |  
|---------------------------------------- |  | --------------------- | --- | - | --------------------- | -
|                                         |  | February
    28, 2014 |     |   | February
    28, 2013 |  
|                                         |  |                       |     |   |                       |  
|Promissory
    Notes                     |  | $                     | 600 |   |                       | $
|Less:
    Equity component of notes      |  |                       | (88 | ) |                       |  
|Less:
    Issue costs                    |  |                       | (17 | ) |                       |  
|                                         |  |                       | 495 |   |                       |  
|Accretion
    in carrying value of notes |  |                       | 20  |   |                       |  
|Balance,
    end of period               |  | $                     | 515 |   |                       | $



b)
Loans payable



In
September 2013 the Company entered into loan agreements for proceeds of $150 thousand. The loan agreements are unsecured, bear
interest at a rate of 10% per annum payable quarterly and are due September 30, 2015.



| | 9. | Additional
                                         cash flow disclosures
| | -- | -------------------------------------------------------------------------



Net
change in non-cash operating working capital is summarized as follows:

|                                      |  | Three
    months ended |      |   | Nine
    months ended |  
|------------------------------------- |  | ---------------------- | ---- | - | --------------------- | -
|                                      |  | February
    28        |      |   | February
    28       |  
|                                      |  | 2014                   |      |   | 2013                  |  
|                                      |  |                        |      |   |                       |  
|Prepaid
    expenses and other assets |  | $                      | (7   | ) |                       | $
|Accounts
    payable                  |  |                        | 107  |   |                       |  
|Accrued
    liabilities               |  |                        | (275 | ) |                       |  
|                                      |  | $                      | (175 | ) |                       | $



During
the nine months ended February 28, 2014 the Company accrued and paid $62 thousand in interest expense on the $918 thousand promissory
notes as described in note 6(b). The interest accrues at a rate of 10% per annum. In addition the Company accrued interest during
the nine months ended February 28, 2014 on the loan agreements and convertible promissory notes described in note 8 of $32 thousand.
The interest accrues at a rate of 10% per annum and is paid quarterly. In addition the Company paid interest of $3 thousand at
a rate of 10% per annum to the withheld pay of employees. All amounts withheld from employees had been repaid as of February 28,
2014.



During
the nine months ended November 30, 2012 the Company accrued and paid $6 thousand in interest expense on the $900 thousand promissory
note due to Mr. Abramson repaid on June 25, 2012. The interest accrued at a rate of 10% per annum.



| | 10. | Other
                                         expenses
| | --- | -------------------------------------------------------



Components
of research and development expenses:



|                              |  | Three
    months ended |     |  | Nine
    months ended |  
|----------------------------- |  | ---------------------- | --- |  | --------------------- | -
|                              |  | February
    28        |     |  | February
    28       |  
|                              |  | 2014                   |     |  | 2013                  |  
|                              |  |                        |     |  |                       |  
|Program
    costs (note 11)   |  | $                      | 519 |  |                       | $
|Stock
    based compensation  |  |                        | 15  |  |                       |  
|Deferred
    share unit costs |  |                        | 59  |  |                       |  
|Depreciation
    of equipment |  |                        | 4   |  |                       |  
|                              |  | $                      | 597 |  |                       | $





F-49







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



Components
of general and administrative expenses:



|                                                  |  | Three
    months ended |       |  | Nine
    months ended |  
|------------------------------------------------- |  | ---------------------- | ----- |  | --------------------- | -
|                                                  |  | February
    28        |       |  | February
    28       |  
|                                                  |  | 2014                   |       |  | 2013                  |  
|                                                  |  |                        |       |  |                       |  
|Stock
    based compensation                      |  | $                      | 334   |  |                       | $
|General
    and administrative excluding salaries |  |                        | 520   |  |                       |  
|Salaries                                          |  |                        | 780   |  |                       |  
|Deferred
    share unit costs                     |  |                        | 136   |  |                       |  
|Depreciation
    of equipment                     |  |                        | 1     |  |                       |  
|                                                  |  | $                      | 1,771 |  |                       | $



| | 11. | Research
                                         and development programs:
| | --- | ---------------------------------------------------------------------------



Program
costs by product class are as follows:



|                    |  | Three
    months ended February 28 |     |  | Nine
    months ended February 28 |  
|------------------- |  | ---------------------------------- | --- |  | --------------------------------- | -
|                    |  | 2014                               |     |  | 2013                              |  
|                    |  |                                    |     |  |                                   |  
|Small
    molecules |  | $                                  | 519 |  |                                   | $
|                    |  |                                    |     |  |                                   |  
|Immunotherapy       |  |                                    | ─   |  |                                   |  
|                    |  |                                    |     |  |                                   |  
|Total               |  | $                                  | 519 |  |                                   | $



| | 12. | Commitments,
                                         contingencies and guarantees.
| | --- | -----------------------------------------------------------------------------------



The
Company entered into various contracts with service providers with respect to the LOR-253 phase I solid tumor clinical trial clinical
trial completed in 2013.  These contracts could have resulted in future payment commitments of approximately $1.5 million. 
Of this amount, $1.1 million has been paid and $73 thousand has been accrued at February 28, 2014 (May 31, 2013 - $740 thousand
paid and $253 thousand accrued).  The Company does not anticipate any additional costs being incurred under these contracts
and will enter into new contracts with respect to the planned Phase Ib clinical trial.



On
November 27, 2012 the Company announced it had entered into a collaboration agreement with Cancer Research UK for the future development
of immunotherapy IL-17E. Under this collaboration agreement Lorus had committed to provide sufficient quantity of the drug IL-17E,
for no cash consideration, to be used by Cancer Research UK in pre-clinical toxicology studies and should those studies be successful,
a Phase I clinical trial. It was expected that this would result in costs of approximately $4 million over a two year period.
In January 2014, the collaboration agreement with Cancer Research UK was terminated and, as such the Company no longer has any
obligation to manufacture IL-17E.



| | 13. | Related
                                         Party Transactions
| | --- | -------------------------------------------------------------------



See
notes 6(a), 8 (a) and 14 for details of related party transactions



These
transactions were in the normal course of business and have been measured at the exchange amount, which is the



amount
of consideration established and agreed to by the related parties.



| | 14. | Subsequent
                                         Events
| | --- | ----------------------------------------------------------



1)
On March 18, 2014 the Company announced the departure of Dr. Aiping Young, former President and Chief Operating Officer. The Company
is prepared to make severance payments of approximately $1.2 million to Dr. Young in accordance with the terms of Dr. Young’s
employment agreement.



2)
Subsequent to the quarter end, on April 10, 2014 we announced the closing of a public offering of our common shares.

As
part of such offering, we issued a total of 50,000,000 common shares at a price of $0.50 per share for aggregate gross proceeds
of $25,000,000. The common shares were sold to a syndicate of underwriters led by RBC Capital Markets and including Roth Capital
Partners and Cormark Securities Inc. and we granted to the underwriters an over-allotment option to purchase up to 7,500,000 additional
common shares at a price of $0.50 per share for a period ending 30 days following the closing of the offering.



The
total costs associated with the transaction were approximately $2.55 million.



F-50







LORUS
THERAPEUTICS INC.

NOTES
TO CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Unaudited)

Three
and nine months ended February 28, 2014 and 2013

(Tabular
amounts are in 000s)



Mr.
Inwentash, a related party of the Company by virtue of exercising control or direction over more than 10% of the common shares
of the Company participated in this offering and acquired an aggregate of 1.3 million common shares.



3)
On April 10, 2014 the Company granted 3,520,000 stock options to directors, members of management and employees at an exercise
price of $0.50. These options will be accounted for in the quarter ended May 31, 2014.



F-51