WARRANT

THE SECURITIES REPRESENTED BY THIS WARRANT AND SECURITIES ISSUABLE UPON EXERCISE
OF THIS WARRANT HAVE BEEN ISSUED PURSUANT TO REGULATION S PROMULGATED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE "1933 ACT"), AND HAVE NOT BEEN
REGISTERED UNDER THE 1933 ACT OR APPLICABLE STATE SECURITIES LAWS. THE
SECURITIES HAVE BEEN ACQUIRED FOR INVESTMENT AND MAY NOT BE OFFERED FOR SALE,
SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION
STATEMENT FOR THE SECURITIES UNDER THE 1933 ACT AND APPLICABLE STATE SECURITIES
LAWS OR AN OPINION OF COUNSEL IN FORM REASONABLY ACCEPTABLE TO THE ISSUER THAT
REGISTRATION IS NOT REQUIRED UNDER THE 1933 ACT. ANY SUCH OFFER, SALE,
ASSIGNMENT OR TRANSFER MUST ALSO COMPLY WITH THE APPLICABLE STATE SECURITIES
LAWS. FURTHERMORE, THIS WARRANT MAY NOT BE EXERCISED BY OR ON BEHALF OF ANY U.S.
PERSON (DEFINED IN REGULATION S UNDER THE 1933 ACT) UNLESS REGISTERED UNDER THE
1933 ACT OR AN EXEMPTION FROM SUCH REGISTRATION IS AVAILABLE.



                        Generex Biotechnology Corporation
                        WARRANT TO PURCHASE COMMON STOCK

Warrant No.: U2000S-[Number]                          Number of Shares: [Number]
Date of Original Issuance: May 17, 2000


Generex Biotechnology Corporation, a Delaware corporation (the "Company"),
hereby certifies that, for Ten United States Dollars ($10.00) and other good and
valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, [Name] the registered holder hereof or its permitted assigns, is
entitled, subject to the terms set forth below, to purchase from the Company
upon surrender of this Warrant, at any time or times on or after the date
hereof, but not after 11:59 P.M. Central Time on the Expiration Date (as defined
herein) [Number] fully paid nonassessable shares of Common Stock (as defined
herein) of the Company (the "Warrant Shares") at the purchase price per share
provided in Section 1(b) below.

     Section 1.

     (a) Securities Purchase Agreement. This Warrant is one of the Warrants (the
"Warrants") issued pursuant to the terms of that certain Securities Purchase
Agreement dated as

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<PAGE>

of May 17, 2000 (the "Closing Date"), among the Company and the Buyers referred
to therein (the "Securities Purchase Agreement").

     (b) Definitions. The following words and terms as used in this Warrant
shall have the following meanings:

          (i) "Approved Stock Plan" shall mean any employee benefit plan as
     defined in Rule 405 under the Securities Act which has been approved by the
     Board of Directors of the Company, pursuant to which the Company's
     securities may be issued to any employee, officer, director, consultant or
     other service provider for services provided to the Company.

          (ii) "Common Stock" means (i) the Company's common stock, $.001 par
     value per share, and (ii) any capital stock into which such Common Stock
     shall have been changed or any capital stock resulting from a
     reclassification of such Common Stock.

          (iii) "Common Stock Deemed Outstanding" means, at any given time, the
     number of shares of Common Stock actually outstanding at such time, plus
     the number of shares of Common Stock deemed to be outstanding pursuant to
     Sections 8(b)(i) and 8(b)(ii) hereof regardless of whether the Options (as
     defined below) or Convertible Securities (as defined below) are actually
     exercisable or convertible at such time, but excluding any shares of Common
     Stock owned or held by or for the account of the Company or issuable upon
     exercise of the Warrants.

          (iv) "Convertible Securities" means any stock or securities (other
     than Options) directly or indirectly convertible into or exchangeable for
     Common Stock.

          (v) "Expiration Date" means the date three (3) years from the date of
     this Warrant or, if such date falls on a Saturday, Sunday or other day on
     which banks are required or authorized to be closed in the City of Chicago
     or the State of Illinois or on which trading does not take place on the
     principal exchange or automated quotation system on which the Common Stock
     is traded (a "Holiday"), the next date that is not a Holiday.

          (vi) "Options" means any rights, warrants or options to subscribe for
     or purchase Common Stock or Convertible Securities.

          (vii) "Other Securities" means (i) the other Warrants, (ii) the shares
     of Common Stock issued pursuant to the Securities Purchase Agreement, (iii)
     securities purchased by Other Purchasers (as defined in the Securities
     Purchase Agreement), and (iv) securities sold through LT&C under the
     Investment Banking Agreement (as those terms are defined in the Securities
     Purchase Agreement).

          (viii) "Person" means an individual, a limited liability company, a
     partnership, a joint venture, a corporation, a trust, an unincorporated
     organization and a government or any department or agency thereof.

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<PAGE>

          (ix) "Principal Market" means the Nasdaq National Market or Nasdaq
     Small-Cap Market.

          (x) "Securities Act" means the Securities Act of 1933, as amended.


          (xi) "Warrant" means this Warrant and all Warrants issued in exchange,
     transfer or replacement of any thereof.

          (xii) "Warrant Exercise Price" shall be $8.6625 per common share,
     subject to adjustment as hereinafter provided.

     Section 2. Exercise of Warrant.

     (a) Subject to the terms and conditions hereof, this Warrant may be
exercised by the holder hereof then registered on the books of the Company, in
whole or in part, at any time on any business day on or after the opening of
business on the date hereof and prior to 11:59 P.M. Central Time on the
Expiration Date by (i) delivery of a written notice, in the form of the
subscription notice attached as Exhibit A hereto (the "Exercise Notice"), of
such holder's election to exercise this Warrant, which notice shall specify the
number of Warrant Shares to be purchased, (ii) (A) payment to the Company of an
amount equal to the Warrant Exercise Price multiplied by the number of Warrant
Shares as to which this Warrant is being exercised (plus any applicable issue or
transfer taxes) (the "Aggregate Exercise Price") in cash or by check or wire
transfer or (B) by notifying the Company that it should subtract from the number
of Warrant Shares issuable to the holder upon such exercise an amount of Warrant
Shares having a last reported sale price (as reported by Bloomberg) on the date
immediately preceding the date of the subscription notice equal to the Aggregate
Exercise Price of the Warrant Shares for which this Warrant is being exercised
(a "Cashless Exercise"), and (iii) the surrender to a common carrier for
delivery to the Company as soon as practicable following such date, this Warrant
(or an indemnification undertaking with respect to this Warrant in the case of
its loss, theft or destruction); provided, that if such Warrant Shares are to be
issued in any name other than that of the registered holder of this Warrant,
such issuance shall be deemed a transfer and the provisions of Section 7 shall
be applicable. In the event of any exercise of the rights represented by this
Warrant in compliance with this Section 2(a), a certificate or certificates for
the Warrant Shares so purchased, in such denominations as may be requested by
the holder hereof and registered in the name of, or as directed by, the holder,
shall be delivered at the Company's expense to, or as directed by, such holder
as soon as practicable, and in no event later than five (5) business days, after
the Company's receipt of the Exercise Notice, the Aggregate Exercise Price and
this Warrant (or an indemnification undertaking with respect to this Warrant in
the case of its loss, theft or destruction). Upon delivery of the Exercise
Notice and Aggregate Exercise Price referred to in clause (ii) (A) above or
notification to the Company of a Cashless Exercise referred to in clause (ii)
(B) above, the holder of this Warrant shall be deemed for all corporate purposes
to have become the holder of record of the Warrant Shares with respect to which
this Warrant has been exercised, irrespective of the date of delivery of this
Warrant as required by clause (iii) above or the certificates evidencing such
Warrant Shares. In the case of a dispute as to the determination of the Warrant
Exercise Price, the Company shall promptly issue to the holder the number of
shares of Common Stock that is not disputed and shall submit the disputed
determinations


                                       3

<PAGE>


or arithmetic calculations to the holder via facsimile within five (5) business
days of receipt of the holder's subscription notice. If the holder and the
Company are unable to agree upon the determination of the Warrant Exercise Price
or arithmetic calculation of the Warrant Shares within five (5) business days of
such disputed determination or arithmetic calculation being submitted to the
holder, then the Company shall immediately submit via facsimile (i) the disputed
determination of the Warrant Exercise Price to an independent, reputable
investment banking firm or (ii) the disputed arithmetic calculation of the
Warrant Shares to its independent, outside accountant. The Company shall cause
the investment banking firm or the accountant, as the case may be, to perform
the determinations or calculations and notify the Company and the holder of the
results no later than forty-eight (48) hours from the time it receives the
disputed determinations or calculations. Such investment banking firm's or
accountant's determination or calculation, as the case may be, shall be deemed
conclusive absent manifest error and the Company shall be liable for the costs
and expenses related to such determination or calculation.

     (b) Unless the rights represented by this Warrant shall have expired or
shall have been fully exercised, the Company shall, as soon as practicable and
in no event later than five (5) business days after any exercise and at its own
expense, issue a new Warrant identical in all respects to this Warrant exercised
except it shall represent rights to purchase the number of Warrant Shares
purchasable immediately prior to such exercise under this Warrant exercised,
less the number of Warrant Shares with respect to which such Warrant is
exercised.

     (c) If the Company shall fail for any reason or for no reason to issue to
the holder on a timely basis as described in this Section 2, a certificate for
the number of shares of Common Stock to which the holder is entitled upon the
holder's exercise of this Warrant or a new Warrant for the number of shares of
Common Stock to which such holder is entitled pursuant to Section 2(b) hereof,
the Company shall, in addition to any other remedies under this Warrant or the
Securities Purchase Agreement or otherwise available to such holder, including
any indemnification under the Securities Purchase Agreement, pay as additional
damages in cash to such holder on each day the issuance of such Common Stock
certificate or new Warrant, as the case may be, is not timely effected an amount
equal to .25% of the product of (A) the sum of the number of shares of Common
Stock not issued to the holder on a timely basis and to which the holder is
entitled and/or, the number of shares represented by the portion of this Warrant
which is not being converted, as the case may be, and (B) the average of the
closing bid price of the Common Stock for the three consecutive trading days
immediately preceding the last possible date which the Company could have issued
such Common Stock or Warrant, as the case may be, to the holder without
violating this Section 2.

     (d) The Company shall not affect any exercise of any Warrant and no holder
of any Warrant shall have the right to exercise any Warrant pursuant to Section
2 to the extent that after giving effect to such exercise such Person (together
with such Person's affiliates) (A) would beneficially own in excess of 4.9% of
the outstanding shares of the Common Stock following such conversion and (B)
would have acquired, through exercise of any Warrant or otherwise, in excess of
4.9% of the outstanding shares of the Common Stock following such exercise
during the 60-day period ending on and including such exercise date. For
purposes of the foregoing sentence, the number of shares of Common Stock
beneficially owned by a Person and its affiliates or acquired by a Person and
its affiliates, as the case may be, shall include the number of shares of Common
Stock

                                       4
<PAGE>

issuable upon exercise of the Warrants with respect to which the determination
of such sentence is being made, but shall exclude the number of shares of Common
Stock which would be issuable upon (i) exercise of the remaining, nonexercisable
Warrants beneficially owned by such Person and its affiliates and (ii) exercise
or conversion of the unexercised or unconverted portion of any other securities
of the Company subject to a limitation on conversion or exercise analogous to
the limitation contained herein beneficially owned by such Person and its
affiliates. Except as set forth in the preceding sentence, for purposes of this
Section 2(d), beneficial ownership shall be calculated in accordance with
Section 13(d) of the Securities Exchange Act of 1934, as amended.
Notwithstanding anything to the contrary contained herein, each Exercise Notice
shall constitute a representation by the holder submitting such Exercise Notice
that, after giving effect to such Exercise Notice, (A) the holder will not
beneficially own (as determined in accordance with this Section 2(d)) and (B)
during the 60-day period ending on and including such exercise date, the holder
will not have acquired, through exercise of any Warrant or otherwise, a number
of shares of Common Stock in excess of 4.9% of the outstanding shares of Common
Stock as reflected in the Company's most recent Form 10-Q or Form 10-K, as the
case may be, or more recent public press release or other public notice by the
Company setting forth the number of shares of Common Stock outstanding, but
after giving effect to exercise of any Warrant by such holder since the date as
of which such number of outstanding shares of Common Stock was reported.

     Section 3. Covenants as to Common Stock. The Company hereby covenants and
agrees as follows:

          (a) This Warrant is, and any Warrant issued in substitution for or
     replacement of this Warrant will upon issuance be, duly authorized and
     validly issued.

          (b) All Warrant Shares which may be issued upon the exercise of the
     rights represented by this Warrant will, upon issuance, be validly issued,
     fully paid and nonassessable and free from all taxes, liens and charges
     with respect to the issue thereof.

          (c) During the period within which the rights represented by this
     Warrant may be exercised, the Company will at all times have authorized and
     reserved at least 100% of the number of shares of Common Stock needed to
     provide for the exercise of the rights then represented by this Warrant and
     the par value of said shares will at all times be less than or equal to the
     applicable Warrant Exercise Price.

          (d) The Company shall promptly secure the listing of the shares of
     Common Stock issuable upon exercise of this Warrant upon each national
     securities exchange or automated quotation system, if any, upon which
     shares of Common Stock are then listed (subject to official notice of
     issuance upon exercise of this Warrant) and shall maintain, so long as any
     other shares of Common Stock shall be so listed, such listing of all shares
     of Common Stock from time to time issuable upon the exercise of this
     Warrant; and the Company shall so list on each national securities exchange
     or automated quotation system, as the case may be, and shall maintain such
     listing of, any other shares of capital stock of the Company issuable upon
     the exercise of this Warrant if and so long

                                       5
<PAGE>

     as any shares of the same class shall be listed on such national
     securities exchange or automated quotation system.

          (e) The Company will not, by amendment of its Certificate of
     Incorporation or through any reorganization, transfer of assets,
     consolidation, merger, dissolution, issue or sale of securities, or any
     other voluntary action, avoid or seek to avoid the observance or
     performance of any of the terms to be observed or performed by it
     hereunder, but will at all times in good faith assist in the carrying out
     of all the provisions of this Warrant and in the taking of all such action
     as may reasonably be requested by the holder of this Warrant in order to
     protect the exercise privilege of the holder of this Warrant against
     dilution or other impairment, consistent with the tenor and purpose of this
     Warrant will take all such actions as may be necessary or appropriate in
     order that the Company may validly and legally issue fully paid and
     nonassessable shares of Common Stock upon the exercise of this Warrant.

          (f) This Warrant will be binding upon any entity succeeding to the
     Company by merger, consolidation or acquisition of all or substantially all
     of the Company's assets.

     Section 4. Taxes. The Company shall pay any and all taxes which may be
payable with respect to the issuance and delivery of Warrant Shares upon
exercise of this Warrant.

     Section 5. Warrant Holder Not Deemed a Stockholder. Except as otherwise
specifically provided herein, no holder, as such, of this Warrant shall be
entitled to vote or receive dividends or be deemed the holder of shares of the
Company for any purpose, nor shall anything contained in this Warrant be
construed to confer upon the holder hereof, as such, any of the rights of a
stockholder of the Company or any right to vote, give or withhold consent to any
corporate action (whether any reorganization, issue of stock, reclassification
of stock, consolidation, merger, conveyance or otherwise), receive notice of
meetings, receive dividends or subscription rights, or otherwise, prior to the
issuance to the holder of this Warrant of the Warrant Shares which he or she is
then entitled to receive upon the due exercise of this Warrant. In addition,
nothing contained in this Warrant shall be construed as imposing any liabilities
on such holder to purchase any securities (upon exercise of this Warrant or
otherwise) or as a stockholder of the Company, whether such liabilities are
asserted by the Company or by creditors of the Company. Notwithstanding this
Section 5, the Company will provide the holder of this Warrant with copies of
the same notices and other information given to the stockholders of the Company
generally, contemporaneously with the giving thereof to the stockholders.

     Section 6. Representations of Holder.

     (a) The holder of this Warrant, by the acceptance hereof, represents that
it is acquiring this Warrant and the Warrant Shares for its own account for
investment only and not with a view towards, or for resale in connection with,
the public sale or distribution of this Warrant or the Warrant Shares, except
pursuant to sales registered or exempted under the Securities Act; provided,
however, that by making the representations herein, the holder does not agree to
hold this Warrant or any of the Warrant Shares for any minimum or other specific
term and reserves the right to dispose of this Warrant and the Warrant Shares at
any time in accordance with or pursuant to a

                                       6
<PAGE>

registration statement or an exemption under the Securities Act. The holder of
this Warrant further represents, by acceptance hereof, that, as of this date,
such holder is an "accredited investor" as such term is defined in Rule
501(a)(1) of Regulation D promulgated by the Securities and Exchange Commission
under the Securities Act (an "Accredited Investor").

     (b) Upon exercise of this Warrant, the holder hereof shall provide the
Company with written certification that (i) such holder is not a U.S. person
(defined in Regulation S under the Securities Act) and (ii) this Warrant is not
being exercised on behalf of a U.S. person.

     (c) The holder hereof acknowledges that this Warrant may not be exercised
in the United States (as defined in Regulation S) and that the Warrant Shares
may not be delivered within the United States upon exercise, unless delivered in
offerings deemed to meet the definition of offshore transaction (defined in
Regulation S under the Securities Act) unless registered under the Securities
Act, or unless an exemption from such registration is available.


     Section 7. Ownership and Transfer.

     (a) The Company shall maintain at its principal executive offices (or such
other office or agency of the Company as it may designate by notice to the
holder hereof), a register for this Warrant, in which the Company shall record
the name and address of the person in whose name this Warrant has been issued,
as well as the name and address of each transferee. The Company may treat the
person in whose name any Warrant is registered on the register as the owner and
holder thereof for all purposes, notwithstanding any notice to the contrary, but
in all events recognizing any transfers made in accordance with the terms of
this Warrant.

     (b) This Warrant and the rights granted to the holder hereof are
transferable, in whole or in part, upon surrender of this Warrant, together with
a properly executed warrant power in the form of Exhibit B attached hereto;
provided, however, that any transfer or assignment shall be subject to the
conditions set forth in Section 7(c) below.

     (c) The holder of this Warrant understands that this Warrant has not been
and is not expected to be, registered under the Securities Act or any state
securities laws, and may not be offered for sale, sold, assigned or transferred
unless (a) subsequently registered thereunder, or (b) such holder shall have
delivered to the Company an opinion of counsel, in generally acceptable form, to
the effect that the securities to be sold, assigned or transferred may be sold,
assigned or transferred pursuant to Regulation S under the Securities Act or to
an exemption from such registration; provided that (i) any sale of such
securities made in reliance on Rule 144 promulgated under the Securities Act may
be made only in accordance with the terms of said Rule and further, if said Rule
is not applicable, any resale of such securities under circumstances in which
the seller (or the person through whom the sale is made) may be deemed to be an
underwriter (as that term is defined in the Securities Act) may require
compliance with some other exemption under the Securities Act or the rules and
regulations of the Securities and Exchange Commission thereunder; and (ii)
neither the Company nor any other person is under any obligation to register the
Warrants

                                       7
<PAGE>

under the Securities Act or any state securities laws or to comply with the
terms and conditions of any exemption thereunder.

     (d) The Company is obligated to register the Warrant Shares for resale
under the Securities Act pursuant to the Registration Rights Agreement dated May
17, 2000 by and between the Company and the Buyers listed on the signature page
thereto (the "Registration Rights Agreement") and the initial holder of this
Warrant (and certain assignees thereof) is entitled to the registration rights
in respect of the Warrant Shares as set forth in the Registration Rights
Agreement.

     Section 8. Adjustment of Warrant Exercise Price and Number of Shares. The
Warrant Exercise Price and the number of shares of Common Stock issuable upon
exercise of this Warrant shall be adjusted from time to time as follows:

     (a) Adjustment of Warrant Exercise Price and Number of Shares upon Issuance
of Common Stock. Except for Company Common Stock issued upon exercise or
conversion of securities issued or contractual rights binding on the Company
outstanding prior to the Closing Date, if and whenever on or after the date of
issuance of this Warrant, the Company issues or sells, or in accordance with
Section 8(b) is deemed to have issued or sold, any shares of Common Stock
(including the issuance or sale of shares of Common Stock owned or held by or
for the account of the Company, but excluding Other Securities or shares of
Common Stock deemed to have been issued by the Company in connection with an
Approved Stock Plan or upon exercise or conversion of the Other Securities) for
a consideration per share less than the Warrant Exercise Price in effect
immediately prior to such time (the "Applicable Price"), then immediately after
such issue or sale the Warrant Exercise Price then in effect shall be reduced to
an amount equal to the product of (x) the Warrant Exercise Price in effect
immediately prior to such issue or sale and (y) the quotient determined by
dividing (1) the sum of (I) the product derived by multiplying the Applicable
Price by the number of shares of Common Stock Deemed Outstanding immediately
prior to such issue or sale, plus (II) the consideration, if any, received by
the Company upon such issue or sale, by (2) the product derived by multiplying
the (I) Applicable Price by (II) the number of shares of Common Stock Deemed
Outstanding immediately after such issue or sale. Upon each such adjustment of
the Warrant Exercise Price hereunder, the number of shares of Common Stock
acquirable upon exercise of this Warrant shall be adjusted to the number of
shares determined by multiplying the Warrant Exercise Price in effect
immediately prior to such adjustment by the number of shares of Common Stock
acquirable upon exercise of this Warrant immediately prior to such adjustment
and dividing the product thereof by the Warrant Exercise Price resulting from
such adjustment.

     (b) Effect on Warrant Exercise Price of Certain Events. For purposes of
determining the adjusted Warrant Exercise Price under Section 8(a) above, the
following shall be applicable:

          (i) Issuance of Options. If the Company in any manner grants any
     Options and the lowest price per share for which one share of Common Stock
     is issuable upon the exercise of any such Option or upon conversion or
     exchange of any Convertible Securities issuable upon exercise of any such
     Option is less than the Applicable Price, then such share of Common Stock
     shall be deemed to be outstanding and to have been issued and sold by the
     Company at the

                                       8
<PAGE>

     time of the granting or sale of such Option for such price per share.
     For purposes of this Section 8(b)(i), the "lowest price per share for which
     one share of Common Stock is issuable upon exercise of such Options or upon
     conversion or exchange of such Convertible Securities" shall be equal to
     the sum of the lowest amounts of consideration (if any) received or
     receivable by the Company with respect to any one share of Common Stock
     upon the granting or sale of the Option, upon exercise of the Option and
     upon conversion or exchange of any Convertible Security issuable upon
     exercise of such Option. No further adjustment of the Warrant Exercise
     Price shall be made upon the actual issuance of such Common Stock or of
     such Convertible Securities upon the exercise of such Options or upon the
     actual issuance of such Common Stock upon conversion or exchange of such
     Convertible Securities. Notwithstanding the foregoing, no adjustment shall
     be made pursuant to this Section 8(b)(i) to the extent that such adjustment
     is based solely on the fact that the Convertible Securities issuable upon
     exercise of such Option are convertible into or exchangeable for Common
     Stock at a price which varies with the market price of the Common Stock.

          (ii) Issuance of Convertible Securities. If the Company in any manner
     issues or sells any Convertible Securities and the lowest price per share
     for which one share of Common Stock is issuable upon such conversion or
     exchange thereof is less than the Applicable Price, then such share of
     Common Stock shall be deemed to be outstanding and to have been issued and
     sold by the Company at the time of the issuance or sale of such Convertible
     Securities for such price per share. For the purposes of this Section
     8(b)(ii), the "lowest price per share for which one share of Common Stock
     is issuable upon such conversion or exchange" shall be equal to the sum of
     the lowest amounts of consideration (if any) received or receivable by the
     Company with respect to one share of Common Stock upon the issuance or sale
     of the Convertible Security and upon conversion or exchange of such
     Convertible Security. No further adjustment of the Warrant Exercise Price
     shall be made upon the actual issuance of such Common Stock upon conversion
     or exchange of such Convertible Securities, and if any such issue or sale
     of such Convertible Securities is made upon exercise of any Options for
     which adjustment of the Warrant Exercise Price had been or are to be made
     pursuant to other provisions of this Section 8(b), no further adjustment of
     the Warrant Exercise Price shall be made by reason of such issue or sale.
     Notwithstanding the foregoing, no adjustment shall be made pursuant to this
     Section 8(b)(ii) to the extent that such adjustment is based solely on the
     fact that such Convertible Securities are convertible into or exchangeable
     for Common Stock at a price which varies with the market price of the
     Common Stock.

          (iii) Change in Option Price or Rate of Conversion. If the purchase
          price provided for in any Options, the additional consideration, if
     any, payable upon the issue, conversion or exchange of any Convertible
     Securities, or the rate at which any Convertible Securities are convertible
     into or exchangeable for Common Stock changes at any time, the Warrant
     Exercise Price in effect at the time of such change shall be adjusted to
     the Warrant Exercise Price which would have been in effect at such time had
     such Options or Convertible Securities provided for such changed purchase
     price, additional consideration or changed conversion rate, as the case may
     be, at the time initially granted, issued or sold and the number of shares
     of Common Stock acquirable hereunder shall be correspondingly readjusted.
     For purposes of this Section 8(b)(iii), if the terms of any Option or
     Convertible Security that was outstanding as of the date of issuance of
     this Warrant are changed in the manner described in the immediately
     preceding sentence, then such Option or Convertible Security and the Common
     Stock deemed issuable upon exercise, conversion or exchange thereof

                                       9
<PAGE>

     shall be deemed to have been issued as of the date of such change. No
     adjustment shall be made if such adjustment would result in an increase of
     the Warrant Exercise Price then in effect. (c) Effect on Warrant Exercise
     Price of Certain Events. For purposes of determining the adjusted Warrant
     Exercise Price under Sections 8(a) and 8(b), the following shall be
     applicable:

          (i) Calculation of Consideration Received. In case any Option is
     issued in connection with the issue or sale of other securities of the
     Company, together comprising one integrated transaction in which no
     specific consideration is allocated to such Options by the parties thereto,
     the Options will be deemed to have been issued for a consideration of $.01.
     If any Common Stock, Options or Convertible Securities are issued or sold
     or deemed to have been issued or sold for cash, the consideration received
     therefor will be deemed to be the net amount received by the Company
     therefor. If any Common Stock, Options or Convertible Securities are issued
     or sold for a consideration other than cash, the amount of such
     consideration received by the Company will be the fair value of such
     consideration, except where such consideration consists of publicly-traded
     securities, in which case the amount of consideration received by the
     Company will be the market price of such securities for the twenty (20)
     consecutive trading days immediately preceding the date of receipt. If any
     Common Stock, Options or Convertible Securities are issued to the owners of
     the non-surviving entity in connection with any merger in which the Company
     is the surviving entity, the amount of consideration therefor will be
     deemed to be the fair value of such portion of the net assets and business
     of the non-surviving entity as is attributable to such Common Stock,
     Options or Convertible Securities, as the case may be. The fair value of
     any consideration other than cash or publicly-held securities will be
     determined jointly by the Company and the holders of Warrants representing
     a majority of the shares of Common Stock obtainable upon exercise of the
     Warrants then outstanding. If such parties are unable to reach agreement
     within ten (10) days after the occurrence of an event requiring valuation
     (the "Valuation Event"), the fair value of such consideration will be
     determined within five business days after the tenth (10th) day following
     the Valuation Event by an independent, reputable appraiser jointly selected
     by the Company and the holders of Warrants representing a majority of the
     shares of Common Stock obtainable upon exercise of the Warrants then
     outstanding. The determination of such appraiser shall be final and binding
     upon all parties and the fees and expenses of such appraiser shall be borne
     by the Company.

          (ii) Record Date. If the Company takes a record of the holders of
     Common Stock for the purpose of entitling them (1) to receive a dividend or
     other distribution payable in Common Stock, Options or in Convertible
     Securities or (2) to subscribe for or purchase Common Stock, Options or
     Convertible Securities, then such record date will be deemed to be the date
     of the issue or sale of the shares of Common Stock deemed to have been
     issued or sold upon the declaration of such dividend or the making of such
     other distribution or the date of the granting of such right of
     subscription or purchase, as the case may be.

     (d) Adjustment of Warrant Exercise Price upon Subdivision or Combination of
Common Stock. If the Company at any time after the date of issuance of this
Warrant subdivides (by any stock split, stock dividend, recapitalization or
otherwise) one or more classes of its outstanding shares of Common Stock into a
greater number of shares, the Warrant Exercise Price in effect immediately prior
to such subdivision will be proportionately reduced and the number of shares of
Common Stock obtainable upon exercise of this Warrant will be proportionately
increased. If the Company at any time after the date of issuance of this Warrant
combines (by combination,

                                       10
<PAGE>

reverse stock split or otherwise) one or more classes of its outstanding shares
of Common Stock into a smaller number of shares, the Warrant Exercise Price in
effect immediately prior to such combination will be proportionately increased
and the number of shares of Common Stock obtainable upon exercise of this
Warrant will be proportionately decreased.

     (e) Distribution of Assets. If the Company shall declare or make any
dividend or other distribution of its assets (or rights to acquire its assets)
to holders of Common Stock, by way of return of capital or otherwise (including,
without limitation, any distribution of cash, stock or other securities,
property or options by way of a dividend, spin off, reclassification, corporate
rearrangement or other transaction) (a "Distribution"), at any time after the
issuance of this Warrant, then, in each such case:

          (i) the Warrant Exercise Price in effect immediately prior to the
     close of business on the record date fixed for the determination of holders
     of Common Stock entitled to receive the Distribution shall be reduced,
     effective as of the close of business on such record date, to a price
     determined by multiplying such Warrant Exercise Price by a fraction of
     which (A) the numerator shall be the Closing bid price on the trading day
     immediately preceding such record date minus the value of the Distribution
     (as determined in good faith by the Company's Board of Directors)
     applicable to one share of Common Stock, and (B) the denominator shall be
     the Closing bid price on the trading day immediately preceding such record
     date; and

          (ii) either (A) the number of Warrant Shares obtainable upon exercise
     of this Warrant shall be increased to a number of shares equal to the
     number of shares of Common Stock obtainable immediately prior to the close
     of business on the record date fixed for the determination of holders of
     Common Stock entitled to receive the Distribution multiplied by the
     reciprocal of the fraction set forth in the immediately preceding clause
     (i), or (B) in the event that the Distribution is of common stock of a
     company whose common stock is traded on a national securities exchange or a
     national automated quotation system, then the holder of this Warrant shall
     receive an additional warrant to purchase Common Stock, the terms of which
     shall be identical to those of this Warrant, except that such warrant shall
     be exercisable into the amount of the assets that would have been payable
     to the holder of this Warrant pursuant to the Distribution had the holder
     exercised this Warrant immediately prior to such record date and with an
     exercise price equal to the amount by which the exercise price of this
     Warrant was decreased with respect to the Distribution pursuant to the
     terms of the immediately preceding clause (i).

     (f) Certain Events. If any event occurs of the type contemplated by the
provisions of this Section 8 but not expressly provided for by such provisions
(including, without limitation, the granting of stock appreciation rights,
phantom stock rights or other rights with equity features), then the Company's
Board of Directors will make an appropriate adjustment in the Warrant Exercise
Price and the number of shares of Common Stock obtainable upon exercise of this
Warrant so as to protect the rights of the holders of the Warrants; provided
that no such adjustment will increase the Warrant Exercise Price or decrease the
number of shares of Common Stock obtainable as otherwise determined pursuant to
this Section 8.

                                       11
<PAGE>


     (g) Notices.

          (i) Immediately upon any adjustment of the Warrant Exercise Price, the
     Company will give written notice thereof to the holder of this Warrant,
     setting forth in reasonable detail, and certifying, the calculation of such
     adjustment.

          (ii) The Company will give written notice to the holder of this
     Warrant at least twenty (20) days prior to the date on which the Company
     closes its books or takes a record (A) with respect to any dividend or
     distribution upon the Common Stock, (B) with respect to any pro rata
     subscription offer to holders of Common Stock or (C) for determining rights
     to vote with respect to any Organic Change (as defined below), dissolution
     or liquidation, provided that such information shall be made known to the
     public prior to or in conjunction with such notice being provided to such
     holder.

          (iii) The Company will also give written notice to the holder of this
     Warrant at least twenty (20) days prior to the date on which any Organic
     Change, dissolution or liquidation will take place, provided that such
     information shall be made known to the public prior to or in conjunction
     with such notice being provided to such holder.

     Section 9. Purchase Rights; Reorganization, Reclassification,
Consolidation, Merger or Sale. (a) In addition to any adjustments pursuant to
Section 8 above, if at any time the Company grants, issues or sells any Options,
Convertible Securities or rights to purchase stock, warrants, securities or
other property pro rata to the record holders of any class of Common Stock (the
"Purchase Rights"), then the holder of this Warrant will be entitled to acquire,
upon the terms applicable to such Purchase Rights, the aggregate Purchase Rights
which such holder could have acquired if such holder had held the number of
shares of Common Stock acquirable upon complete exercise of this Warrant
immediately before the date on which a record is taken for the grant, issuance
or sale of such Purchase Rights, or, if no such record is taken, the date as of
which the record holders of Common Stock are to be determined for the grant,
issue or sale of such Purchase Rights.

     (b) Any recapitalization, reorganization, reclassification, consolidation,
merger, sale of all or substantially all of the Company's assets to another
Person or other transaction which is effected in such a way that holders of
Common Stock are entitled to receive (either directly or upon subsequent
liquidation) stock, securities or assets with respect to or in exchange for
Common Stock is referred to herein as "Organic Change." Prior to the
consummation of any (i) sale of all or substantially all of the Company's assets
to an acquiring Person or (ii) other Organic Change following which the Company
is not a surviving entity, the Company will secure from the Person purchasing
such assets or the successor resulting from such Organic Change (in each case,
the "Acquiring Entity") written agreement (in form and substance satisfactory to
the holders of Warrants representing a majority of the shares of Common Stock
obtainable upon exercise of the Warrants then outstanding) to deliver to each
holder of Warrants in exchange for such Warrants, a security of the Acquiring
Entity evidenced by a written instrument substantially similar in form and
substance to this Warrant and satisfactory to the holders of the Warrants
(including, an adjusted warrant exercise price equal to the value for the Common
Stock reflected by the terms of such

                                       12
<PAGE>

consolidation, merger or sale, and exercisable for a corresponding number of
shares of Common Stock acquirable and receivable upon exercise of the Warrants,
if the value so reflected is less than the Warrant Exercise Price in effect
immediately prior to such consolidation, merger or sale). Prior to the
consummation of any other Organic Change, the Company shall make appropriate
provision (in form and substance satisfactory to the holders of Warrants
representing a majority of the shares of Common Stock obtainable upon exercise
of the Warrants then outstanding) to insure that each of the holders of the
Warrants will thereafter have the right to acquire and receive in lieu of or in
addition to (as the case may be) the shares of Common Stock immediately
theretofore acquirable and receivable upon the exercise of such holder's
Warrants, such shares of stock, securities or assets that would have been issued
or payable in such Organic Change with respect to or in exchange for the number
of shares of Common Stock which would have been acquirable and receivable upon
the exercise of such holder's Warrant as of the date of such Organic Change
(without taking into account any limitations or restrictions on the
exercisability of this Warrant).

     Section 10. Lost, Stolen, Mutilated or Destroyed Warrant. If this Warrant
is lost, stolen, mutilated or destroyed, the Company shall, on receipt of an
indemnification undertaking, issue a new Warrant of like denomination and tenor
as this Warrant so lost, stolen, mutilated or destroyed.

     Section 11. Notice. Any notices, consents, waivers or other communications
required or permitted to be given under the terms of this Warrant must be in
writing and will be deemed to have been delivered: (i) upon receipt, when
delivered personally; (ii) upon receipt, when sent by facsimile (provided
confirmation of transmission is mechanically or electronically generated and
kept on file by the sending party); or (iii) one business day after deposit with
a nationally recognized overnight delivery service, in each case properly
addressed to the party to receive the same. The addresses and facsimile numbers
for such communications shall be:

                  If to the Company:

                           Generex Biotechnology Corporation
                           33 Harbour Square, Suite 202
                           Toronto, Canada M5J 2G2
                           Telephone: (416) 364-2551
                           Facsimile: (416) 364-9363
                           Attention: E. Mark Perri

                  With copy to:

                           Eckert Seamans Cherin & Mellott
                           1515 Market Street, 9th Floor
                           Philadelphia, Pennsylvania 19102-1909
                           Telephone: (215) 851-8410
                           Facsimile: (215) 851-8383
                           Attention: Joseph Chicco, Esq.

                                       13
<PAGE>


If to a holder of this Warrant, to it at the address and facsimile number set
forth on the Schedule of Buyers to the Securities Purchase Agreement, with
copies to such holder's representatives as set forth on such Schedule of Buyers,
or at such other address and facsimile as shall be delivered to the Company upon
the issuance or transfer of this Warrant. Each party shall provide five days'
prior written notice to the other party of any change in address or facsimile
number. Written confirmation of receipt (A) given by the recipient of such
notice, consent, waiver or other communication, (B) mechanically or
electronically generated by the sender's facsimile machine containing the time,
date, recipient facsimile number and an image of the first page of such
transmission or (C) provided by a nationally recognized overnight delivery
service shall be rebuttable evidence of personal service, receipt by facsimile
or receipt from a nationally recognized overnight delivery service in accordance
with clause (i), (ii) or (iii) above, respectively.

     Section 12. Amendments. This Warrant and any term hereof may be changed,
waived, discharged, or terminated only by an instrument in writing signed by the
party or holder hereof against which enforcement of such change, waiver,
discharge or termination is sought.

     Section 13. Date. The date of this Warrant is May 17, 2000. This Warrant,
in all events, shall be wholly void and of no effect after the close of business
on the Expiration Date, except that notwithstanding any other provisions hereof,
the provisions of Section 7 shall continue in full force and effect after such
date as to any Warrant Shares or other securities issued upon the exercise of
this Warrant.

     Section 14. Amendment and Waiver. Except as otherwise provided herein, the
provisions of the Warrants may be amended and the Company may take any action
herein prohibited, or omit to perform any act herein required to be performed by
it, only if the Company has obtained the written consent of the holders of
Warrants representing a majority of the shares of Common Stock obtainable upon
exercise of the Warrants then outstanding; provided that no such action may
increase the Warrant Exercise Price of the Warrants or decrease the number of
shares or class of stock obtainable upon exercise of any Warrants without the
written consent of the holder of such Warrant.

     Section 15. Descriptive Headings; Governing Law. The descriptive headings
of the several Sections and paragraphs of this Warrant are inserted for
convenience only and do not constitute a part of this Warrant. This Warrant
shall be governed by the internal laws of the State of Illinois, without giving
effect to any choice of law or conflict of law provision or rule (whether of the
State of Illinois or any other jurisdictions) that would cause the application
of the laws of any jurisdictions other than the State of Illinois.

                            [Signature Page Follows]


                                       14
<PAGE>


     This Warrant has been duly executed by the Company as of the date set forth
in Section 13 above.


                                        GENEREX BIOTECHNOLOGY CORPORATION



                                        By:
                                           -------------------------------------
                                        Name:
                                             -----------------------------------
                                        Title:
                                              ----------------------------------




<PAGE>


                              EXHIBIT A TO WARRANT

                                SUBSCRIPTION FORM

        TO BE EXECUTED BY THE REGISTERED HOLDER TO EXERCISE THIS WARRANT

                        GENEREX BIOTECHNOLOGY CORPORATION

     The undersigned holder hereby exercises the right to purchase
_________________ of the shares of Common Stock ("Warrant Shares") of Generex
Biotechnology Corporation, a Delaware corporation (the "Company"), evidenced by
the attached Warrant (the "Warrant"). Capitalized terms used herein and not
otherwise defined shall have the respective meanings set forth in the Warrant.

     1. Form of Warrant Exercise Price. The Holder intends that payment of the
Warrant Exercise Price shall be made as:

          a "Cash Exercise" with respect to _______________________ Warrant
          Shares which shall result in the holder owning ___% of the Company's
          common stock on a fully diluted basis; and/or

          a "Cashless Exercise" with respect to ___________________ Warrant
          Shares which shall result in the holder owning ___% of the Company's
          common stock on a fully diluted basis.

     2. Payment of Warrant Exercise Price. In the event that the holder has
elected a Cash Exercise with respect to some or all of the Warrant Shares to be
issued pursuant hereto, the holder shall pay the sum of $___________________ to
the Company in accordance with the terms of the Warrant.

     3. Delivery of Warrant Shares. The Company shall deliver to the holder
__________ Warrant Shares in accordance with the terms of the Warrant.


Date:                               ,
     ---------------------- --------  ---------------




   Name of Registered Holder

By:
    ------------------------------------
Name:
     -----------------------------------
Title:
      ----------------------------------


<PAGE>

                              EXHIBIT B TO WARRANT

                              FORM OF WARRANT POWER


FOR VALUE RECEIVED, the undersigned does hereby assign and transfer to
________________, Federal Identification No. __________, a warrant to purchase
____________ shares of the capital stock of Generex Biotechnology Corporation, a
Delaware corporation, represented by warrant certificate no. _____, standing in
the name of the undersigned on the books of said corporation. The undersigned
does hereby irrevocably constitute and appoint ______________, attorney to
transfer the warrants of said corporation, with full power of substitution in
the premises.


Dated:  _________, 200_






                                        By:
                                           -------------------------------------
                                        Name:
                                             -----------------------------------
                                        Title:
                                              ----------------------------------