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Title:   Author  item
                                            DALLOUL, R - U MD COLLEGE PARKitem
                                            Lillehoj, Hyunitem
                                            DIERR, H - U MD COLLEGE PARK
  Submitted to: Poultry Science Meeting
                                    Publication Type: Abstract Only
                                    Publication Acceptance Date: 5/30/2001
                                    Publication  Date: N/A
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Previously we reported increased resistance (reduced fecal oocyst) in Lactobacillus-treated broilers to Eimeria acervulina (EA).  The present study was designed to examine IFM-gamma (interferon-gamma) and oocyst production.  Day-old male (24 chicks/diet) chicks were orally challenged with 10-4 oocysts of EA on day 20 after treating with PRO diets.  Sera and  intestinal secretions were sampled at 3, 6, 9, and 12 days post infection (DPI).  In Exp. 2 (8 chicks/diet), chickens were challenged with 2x10-4 oocysts/bird.  Intestinal IFN-gamma in CON chicks was constant through the sampling period except at 6 DPI when a significant (P<.05) increase occurred.  In contrast, PRO chicks had a significantly higher IFN-gamma at 3 DPI, which then declined until 12 DPI(P<0.05).  No differences in serum, IFN-gamma were observed.  No significant difference in anti-coccidial antobodies was noted (secretory or circulatory).  Fecal oocyst shedding was sslightly but significantly lower (P <0.05) for PRO than for CON chicks; however, the reduction in shedding was not as great as in a previous study when half the inoculum rate was used.  These results suggest a immuno- regulatory effect of PROdiets on the local immune system in poultry and provide a rationale for further study to investigate the beneficial effects of PRO diets in food animals.


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