Exhibit
10.1


 





 


Stock
Purchase Agreement between


Beijing
Kanghuayuan Medicine


Information
Consulting Co., Ltd. and


Shineco
Life Science Research Co., Ltd.


 


Oct.
21, 2022


 


CONTENTS


 




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	I.
    The Parties	4
	II.
    Definitions and Interpretation	5
	III.
    Sale and purchase of target equity	6
	IV.
    Obligations prior to closing	7
	V.
    Closing conditions	7
	VI.
    Closing	9
	VII.
    Transaction consideration and payment terms	9
	VIII.
    Arrangements for transition period	10
	IX.
    Obligations after closing	12
	X.
    Representations, promises or warranties of the Seller	13
	XI.
    Representations, promises or warranties of the Buyer	14
	XII.
    Continuing representations, promises or warranties of the Seller after closing	15
	XIII.
    Liability for breach of contract and termination of agreement	16
	XIV.
    Modification	18
	XV.
    Notice	19
	XVI.
    Secrecy	20
	XVII.
    Tax bearing	20
	XVIII.
    Severability	20
	XIX.
    Governing Law	21
	XX.
    Litigation and arbitration	21
	XXI.
    Language text and effectiveness of the agreement	21
	☐
    Annex I Resolution of the Shareholders’ Meeting of the Target Company	23
	☐
    Annex II List of Main Assets Involved by the Target Company	23
	☐
    Annex III Transfer (Closing) Confirmation	24
	☐
    Annex IV Supplementary Representations, Promises or Warranties of the Seller	25


 




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This
Stock Purchase Agreement (hereinafter referred to as: “this Agreement”) is signed in MM/DD, 2022 in [Chaoyang District,
Beijing] by the following parties:


 


I.
The Parties


 


The
Seller:


 


Beijing
Kanghuayuan Medicine Information Consulting Co., Ltd. (English name: Beijing Kanghuayuan Medicine Information Consulting Co., Ltd., unified
social credit code: 91110108780200387B), a limited liability company legally established and surviving in the People’s Republic
of China, with its registered address at 01, Floor 1, Building 4, Jindayuan Community, Huilongguan Town, Changping District, Beijing,
China, is one of the registered shareholders of the Target Company, legally holding [63.7]% of the Target Company’s equity and
all the corresponding rights and interests. (hereinafter referred to as “the Seller”).


 


The
Buyer:


 


Shineco
Life Science Research Co., Ltd. (English name: Shineco Life Science Research Co., Ltd., unified social credit code: 91110107MA7EKGF43L),
a limited company legally established and surviving in the People’s Republic of China, is a wholly-owned sub-subsidiary of Shineco,
Inc., a NASDAQ listed company (Stock code: SISI). Its registered address is 4119, Floor 4, Building 4, Yard 49, Badachu Road, Shijingshan
District, Beijing, and the office address is Room 3310, North Tower, Zhengda Center, Chaoyang District, Beijing. (hereinafter referred
to as “the Buyer”).


 


Target
Company:


 


Changzhou
Biowin Pharmaceutical Co., Ltd. (English name: Changzhou Biowin Pharmaceutical Co., Ltd., unified social credit code: 913204055866144395),
a limited liability company legally established and surviving in the People’s Republic of China, with its registered address at
Floor 3, Building 3, California Science and Technology Port, No. 218, Fumin Road, Changzhou City, Jiangsu Province, China. (hereinafter
referred to as “the Target Company” or “the Company”).


 




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Under
this Agreement, the Seller and the Buyer are respectively referred to as “one party”, collectively referred to as “both
parties”, and mutually referred to as “the other party”. The Seller, the Buyer and the Target Company are collectively
referred to as “the Parties”.


 


Whereas:
The Seller is willing to sell the target equity (as defined below) to the Buyer in accordance with the terms and conditions set out in
this Agreement, and the Buyer agrees to purchase the target equity from the Seller in accordance with the terms and conditions set out
in this Agreement. Therefore, both parties hereby agree as follows through friendly negotiation:


 


II.
Definitions and Interpretation


 


2.1
In this Agreement and its annexes, unless the context otherwise requires, the following words are defined as follows in this Agreement:


 


	Weekdays
    	It
    refers to the Gregorian calendar day (excluding Saturday and Sunday) on which banks operating in China can normally operate and deposit
    and payment transactions can be conducted between banks 
	Base
    date 	It
    refers to Sep. 30, 2022 
	RMB
    	It
    refers to RMB, the lawful currency of China 
	Chinese
    	It
    refers to the People’s Republic of China, excluding Hong Kong Special Administrative Region, Macao Special Administrative Region
    and Taiwan for the purposes of this Agreement 
	Material
    adverse effect 	It
    refers to any circumstance, change or influence involved in the Company or its business as follows: The circumstance, change or influence
    (a) causes or has sufficient evidence to show that it may cause serious adverse effects on the survival, business, assets, intellectual
    property, liabilities (including but not limited to or liable for), operating performance or financial condition of the Company,
    or causes the loss of the Company and/or its assets to exceed ten percent (10%) of its net assets, or causes that the net profit
    of the current year of the Company is less than ten percent (10%) of the total net profit of the current year predicted by the Company;
    or (b) has a serious adverse effect on the qualification, license or ability of the Company to operate its current business 


 




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	Material
    contracts 	It
    refers to all contracts, agreements, memorandums, letters of intent or other legal documents that are necessary for the survival,
    development, finance or business of the Company, or constitute significant restrictions on the Company, or have a significant adverse
    impact on the survival, development, financial condition or business of the Company in case of absence of such contracts or agreements,
    regardless of whether such contracts or agreements are entered into in the normal course of business operations, including but not
    limited to: (i) Any contract with a transaction amount of more than RMB [100,000], (ii) contract for transfer, sale, license, purchase
    or disposal of important properties or important intellectual property rights of the Company, (iii) exclusive contract or contract
    restricting the Company’s competitiveness, (iv) commercial contract signed with the top ten contractors, suppliers of engineering
    or raw materials, and customers of sales and engineering contracts of the Company, (v) contracts involving equity sales, equity acquisition,
    investment, financing, joint venture, merger and acquisition, reorganization, voting right arrangement, profit sharing, or control
    right transfer, (vi) contracts for setting encumbrance on the Company’s equity or important property, etc., (vii) contract
    or agreement signed with government departments. 


 


2.2
In this Agreement, unless otherwise specified:


 


2.2.1
The mentioned terms and annexes refer to terms and annexes of this Agreement;


 


2.2.2
The headings used in this Agreement are set for convenience only and shall not affect the meaning or interpretation of this Agreement
in any way;


 


2.2.3
The word “including” used in this Agreement shall be interpreted as “including but not limited to”;


 


2.2.4
The annexes shall constitute a part of this Agreement and have the same effect and force as if they are explicitly listed in the body
of this Agreement. Any reference to this Agreement shall include annexes.


 


III.
Sale and purchase of target equity


 


3.1
According to the terms and conditions agreed in this agreement, the seller intends to sell the target equity to the buyer, the buyer
intends to transfer the target equity, list it in the Target Company’s shareholder register, amend the articles of association,
and complete the alteration registration in administration for industry and commerce in the target equity (collectively referred to as
“this transaction”).


 




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3.2
The “target equity” referred to in this Agreement refers to the [51]% equity of the Target Company to be sold to the Buyer
owned by the Seller on the Closing Date.


 


IV.
Obligations prior to closing


 


4.1
Within [30] days after the signing of this Agreement, the Seller and the Target Company shall complete the resolution of the shareholders’
meeting on the resignation of the original director and the replacement of the new director of the Target Company, which shall be reflected
in the industrial and commercial registration.


 


4.2
Within [30] days after the signing of this Agreement, the Seller and the Target Company shall complete the supplementary payment of social
insurance and housing provident fund for full-time employees by the Target Company. In addition, the Target Company and the employees
shall sign a settlement agreement satisfactory to the Buyer to ensure that the employees will not pursue other compensation or responsibilities,
and there is no dispute or conflict;


 


4.3
Within [30] days after the signing of this Agreement, the Seller and the Target Company shall complete the financial arrangement, overdue
tax payment (if any) and account adjustment of the Target Company to the satisfaction of the Buyer;


 


4.4
Within [30] days after the signing of this Agreement, the Seller shall complete all materials related to the compliant Chinese foreign
joint ventures and alteration registration in administration for industry and commerce under the transaction documents submitted by the
Target Company to the competent government departments (including the commercial department, the market supervision department, the tax
department, etc.);


 


The
expenses required for the above matters shall be borne by the Seller.


 


V.
Closing conditions


 


5.1
The following preconditions for the closing shall be satisfied or appropriately exempted:


 




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5.1.1
The Seller has approved this transaction in accordance with its internal and Target Company’s internal organizational documents,
articles of association, etc.;


 


5.1.2
The representations, promises and warranties made by the Seller under this Agreement are true, accurate, complete and not misleading
until the Closing Date;


 


5.1.3
The Buyer has approved this transaction according to its internal organizational documents and articles of association, etc.;


 


5.1.4
There is no one or more events with significant adverse effects before the Closing Date, and there is no indication that such events
may cause significant adverse effects;


 


5.1.5
The obligations prior to closing to be performed by the Seller on or before the Closing Date specified in this Agreement and other transaction
documents have been fulfilled, and there is no violation of the obligations prior to closing;


 


5.2
Both parties shall make all commercially reasonable efforts to achieve or facilitate the realization of the preconditions listed in Article
5.1 of this Agreement as soon as possible before the Closing Date to the extent that they are obligated to meet the relevant preconditions.


 


5.3
On the basis of friendly negotiation between both parties, both parties can sign a separate confirmation letter to exempt or partially
exempt the preconditions listed in Article 5.1 that cannot be met.


 


5.4
The Parties of this Agreement shall make reasonable efforts to adopt or prompt other person to adopt required, proper or needful relevant
measures as much as possible to conduct or urge other person to conduct all relevant matters according to applicable laws and regulations.
Besides, sign and deliver every necessary document and other materials to implement the terms and conditions of this Agreement, complete
and take effect the proposed transaction of this Agreement.


 




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VI.
Closing


 


6.1
Within [30] days after this Agreement is signed and the closing conditions agreed herein are all met or exempted by the Buyer, the Seller
and the Target Company will include the Buyer in the register of shareholders, complete the amendment of the Articles of Association,
complete the equity closing procedures such as the tax alteration and alteration registration in administration for industry and commerce
of the target equity, and obtain a new business license. Such alteration registration in administration for industry and commerce has
clearly reflected the shareholding situation after the completion of the equity transfer and other relevant matters contained in the
transaction documents.


 


6.2
Within [30] days after the signing of this Agreement and all the closing conditions agreed in this Agreement are met or exempted by the
Buyer, the Target Company shall establish a new board of directors composed of five directors, of which the Buyer shall appoint two directors
and the Chairman shall be the director appointed by the Buyer, the Seller and the original shareholder shall appoint two directors, and
the General Manager shall be the director appointed by the Seller and the original shareholder, and the other director is employed by
the Target Company after the closing, and the board of directors shall be subject to the principle of one person one vote. Complete the
alteration registration in administration for industry and commerce in the appointment of directors, Chairman, General Manager, etc.
within the aforesaid time.


 


6.3
The parties to the agreement shall sign the Transfer (Closing) Confirmation [see Annex III] to confirm the Closing Date, which shall
be deemed as the completion of the closing, after the completion of the above circumstances.


 


VII.
Transaction consideration and payment terms


 


7.1
The transaction consideration of this transaction is RMB [86.7] million (equivalent to USD 12.097 million. The settlement under this
Agreement is made in USD, and the exchange rate is USD 1 =RMB 7.1671, without adjustment). Among them, RMB [64.5] million (i.e., USD
9 million) will be paid in currency, and the remaining RMB [22.2] million (i.e., USD 3,097,000) will be paid by Shineco, Inc. issuing
SISI restricted shares of equal value registered in the Transfer Agent (TA) system to the Seller in accordance with the relevant provisions
of the US securities regulations on exemption from registration and issuance. With reference to the stock price performance of SISI 30
trading days prior to the signing date of this Agreement, both parties have agreed: The value of SISI restricted shares used for consideration
payment is USD 0.95/share. The Buyer shall pay 3.26 million SISI restricted shares to the seller, and the number of shares shall not
be adjusted under any circumstances. (hereinafter referred to as the “transaction consideration”).


 




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7.2
The transaction consideration shall be determined according to the following methods: [The transaction consideration is determined by
the Seller and the Buyer through negotiation based on the total equity value of the shareholders of the Target Company listed in the
Appraisal and Consultation Report issued by Beijing North Asia Asset Assessment Firm (Special General Partnership).]


 


7.3
The payment time shall be determined according to the following methods: For the part of monetary payment consideration, the buyer will
remit USD 9 million (or the equivalent of RMB 64.5 million) to the Seller or its designated bank account after the completion of the
closing and before Dec. 31, 2022; For the share payment consideration, the Buyer issues 3.26 million SISI restricted shares through Shineco,
Inc. and registers them in the name of the Seller or its designee within 30 days after the completion of the closing.


 


VIII.
Arrangements for transition period


 


8.1
The period from the signing date of this Agreement to the Closing Date (excluding the date) (“transition period”), if the
Closing Date is not the end of a month, the transition period shall be the period from the signing date of this Agreement to the end
of the month closest to the Closing Date. During the transition period, in addition to other obligations (if any) to meet the closing
preconditions or activities conducted with the prior written consent of the Buyer, the Seller shall ensure to:


 




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8.1.1
Enable the Target Company to operate in the normal business operation mode in the past;


 


8.1.2
Maintain or update all business contracts and operation qualifications involved in the Target Company;


 


8.1.3
Except for the normal wear and tear of daily operation, there is no substantial or significant value impairment of the Target Company’s
assets; The Target Company’s assets include:


 


A.
The assets listed in the Appraisal and Consultation Report issued by Beijing North Asia Asset Assessment Firm (Special General
Partnership) with Jul. 31, 2022 as the base date (see Annex II);


 


B.
Intellectual property rights directly related to the Target Company (including patent rights, software copyrights, trademarks, domain
names, etc.);


 


C.
As of the Closing Date, all kinds of business contracts related to the Target Company that are still valid and have not been fulfilled
and can bring asset inflow;


 


D.
Relevant assets owned by the Target Company but not included in the scope of due diligence assets on the Closing Date.


 


8.1.4
The Seller shall not directly or indirectly transfer or pledge any of the Target Equity and the Target Company’s assets, shall
not set a third party right on the target equity and the Target Company’s assets, or facilitate, allow or assist the occurrence
of any of the foregoing events;


 


8.2
During the transition period, the profits and losses arising from the assets of the Target Company that should be shared for the target
equity belong to the Buyer.


 


8.3
During the transition period, both parties shall cooperate with each other to further sign or make documents that may need to be signed
or behaviors that may need to be made by both parties for the full implementation of this Agreement and the completion of this transaction.


 




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IX.
Obligations after closing


 


9.1
Within [60] days after the Parties have completed the closing and signed the Transfer (Closing) Confirmation, the Seller and the
Target Company shall cooperate with the Buyer, and the Buyer shall appoint a financial officer (Chief Financial Officer) to manage the
accounting of Target Company.


 


9.2
The Seller is not allowed to operate other businesses outside the Target Company system that are identical with the existing technical
products, patent rights, software copyrights, trademarks and domain names of the Target Company in the name of the Company (in person)
or related parties (close relatives) and other holders. In case of any violation, the Buyer has the right to require the Seller to transfer
all the above assets, dividends or profits obtained and businesses and other contents to the name of the Target Company free of charge
within 30 days after the Buyer’s written notice.


 


9.3
The Seller promises that the revenue attributable to the Target Company in 2023 will not be less than RMB 35 million and the net profit
will not be lower than RMB 5.5 million, the revenue in 2024 shall not be less than RMB 50 million and the net profit shall not be less
than RMB 10 million, and the revenue in 2025 shall not be less than RMB 80 million, and the net profit shall not be less than RMB 20
million. In case of failure of the audited net profit of the Target Company in any year since 2023 to meet the above commitment standards,
the difference shall be deducted from the transaction consideration of this transaction by the Seller according to the Buyer’s
equity ratio, and the Seller shall return it to the Buyer; If the Target Company’s audited net profit for three years accumulatively
since 2023 reaches the above accumulative commitment standard, the Buyer shall return the profit compensation made by the Seller previously.
In case of any subsequent return by the Seller or the Buyer, the specific handling method can be separately agreed by both parties.


 


The
Target Company shall have an audit report issued by an accounting firm with securities practice qualification to confirm the revenue
target and net profit of the previous fiscal year before May 15 of the next year of the preceding year. If the Company does not have
independent audit conditions due to non-standard operation in the operation or does not cooperate with the audit, resulting in the failure
of accounting firm to issue a standard audit report to confirm the above net profit, the actual net profit of the Company shall be deemed
as 0.


 




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X.
Representations, promises or warranties of the Seller


 


10.1
The Seller makes the following representations, promises or warranties to the Buyer on the signing date and the Closing Date of this
Agreement:


 


10.1.1
The Seller is a company legally registered and validly surviving under the laws of China, which has the necessary capacity, power, authorization
and qualification to sign and perform this Agreement, and once this Agreement is formally signed and delivered, the Seller’s legal
and binding obligations shall constitute in accordance with its terms;


 


10.1.2
The Seller’s signing and performance of this Agreement will not result in violation of or conflict with the constitutional or organizational
documents or restrictive documents, agreements, etc. of the Seller and the Target Company.


 


10.1.3
The Seller owns the legal and beneficial ownership of each target equity and Target Company’s assets. No guarantee or other encumbrance
is set for any target equity or Target Company’s assets.


 


10.1.4
The taxes are paid according to laws and regulations, and there are no tax penalties and potential penalties.


 


10.1.5
All disputes arising from the subsequent cancellation of subsidiaries and branches will not affect the rights and interests of the Company
and the Buyer.


 


10.1.6
The Target Company’s liabilities not included in the scope of the assets appraisal of Appraisal and Consultation Report
issued by Beijing North Asia Asset Assessment Firm (Special General Partnership) on the base date of Jul. 31, 2022 shall be borne by
the Seller, and the liabilities within the scope of assets appraisal shall be borne by the Target Company.


 


10.1.7
The Seller has disclosed all matters related to the Target Company to the Buyer, and the disclosed matters are true and complete.


 


10.1.8
In addition to the foregoing representations, promises or warranties, the Seller still needs to make supplementary representations, promises
or warranties [see Annex IV for details].


 




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10.2
The Seller guarantees that if it finds that any matter constitutes or may constitute a violation of or inconsistent with any representations,
promises or warranties under Article [10.1] and other provisions of this Agreement, it will immediately disclose the matter in writing
to the Buyer and bear the liability for breach of contract and compensation.


 


XI.
Representations, promises or warranties of the Buyer


 


11.1
The Buyer makes the following representations, promises or warranties to the Seller on the signing date of this Agreement, the Closing
Date and the date when the Buyer pays the transaction consideration described in this Agreement on time:


 


11.1.1
The Buyer is a company legally registered and validly surviving under the laws of China. The Buyer has the necessary capacity, power,
authorization and qualification to sign and perform this Agreement, and once this Agreement is formally signed and delivered, a legal
and binding obligation of this Agreement shall constitute according to its terms;


 


11.1.2
The signing and performance of this Agreement by the Buyer will not result in violation of or conflict with the constitutional or organizational
documents of the Buyer.


 


11.1.3
There will be enough funds to pay the price, and the price source of the Buyer is legal.


 


11.2
The Buyer guarantees that if it finds any matter constitutes or may constitute a violation of or conflict with any representations, promises
or warranties under Article 11.1, it will immediately disclose the matter to the Seller in writing.


 




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XII.
Continuing representations, promises or warranties of the Seller after closing


 


12.1
Regardless of other provisions of this Agreement, if the Buyer transfers all or part of its equity to one or more other entities controlled
by the ultimate controller of the Buyer, the transfer does not require the consent of the Seller and other shareholders and is not subject
to any right contract of other shareholders (the Seller shall ensure that other shareholders agree to the transfer). The transferee shall
inherit all the rights and obligations of the Buyer under this Agreement as if the transferee is the Buyer.


 


12.2
The Seller and the Target Company shall, in accordance with the provisions of relevant Chinese laws and regulations, and in combination
with various preferential tax treatments granted by the state and government departments to companies engaged in the main business, pay
taxes according to law. the Company shall try its best to obtain the most preferential tax treatment permitted by relevant laws and regulations.


 


12.3
The Buyer shall have the right to inspect the business premise of the Target Company at any time and check the Company’s monthly,
quarterly and annual business records, accounting records, account books, financial reports and archives. The Buyer has the right to
entrust a third party to conduct financial audit on the Target Company. The Seller and the Target Company shall actively cooperate and
provide necessary conditions and materials so that the Buyer can complete the above audit survey, provided that it is within the normal
working hours of the Company and the Buyer sent a written notice to the Target Company ten (10) working days in advance, the cost of
the entrusted inspection shall be borne by the Buyer.


 


12.4
Unless otherwise specified in this Agreement, the Target Company and other shareholders of the Target Company shall cooperate or perform
matters under this Agreement. The Seller shall ensure that the Target Company and other shareholders of the Target Company cooperate
or perform, which shall be included in the Articles of Association. The Seller and the Target Company shall ensure that they are included
in the Articles of Association.


 


12.5
After the completion of the closing, the Seller and the Buyer shall act in concert at the shareholders’ meeting and the board of
directors of the Company. In case of disagreement between the Seller and the Buyer, the Buyer’s opinion shall prevail.


 




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XIII.
Liability for breach of contract and termination of agreement


 


13.1
Liability for breach of contract


 


13.1.1
In case of failure of a party to perform its obligations under this Agreement or any transaction document, or untruthfulness or inaccuracy
of any representations, promises or warranties or disclosure under this Agreement or any transaction document, it will constitute a breach
of this Agreement (the party is the “defaulting party”). In this case, the observant party shall notify the defaulting party
of its breach of this Agreement in writing, and has the right to require the defaulting party to compensated for any and all liabilities,
losses (including value impairment), damages, claims, costs and expenses (including but not limited to the expenditure and expenses incurred
in the process of claiming for breach of contract), interests, rulings, judgments, fines, any claim raised by either party or otherwise
caused (referred to as “loss” in this agreement) borne by the observant party for the above behaviors.


 


13.1.2
If the defaulting party has made it clear (orally, in writing or by conduct) before the expiration of the performance period that it
will not perform its main obligations under this Agreement, or the default of the defaulting party (including those caused by force majeure)
has made it impossible for the Parties to achieve the basic purpose of this Agreement, or the defaulting party has failed to remedy its
major breach within [10] days from the date of the notice of the observant party, then the observant party has the right to terminate
this Agreement.


 


13.1.3
In case of breach of this Agreement or other transaction documents, the defaulting party shall be responsible for all losses of the observant
party caused by its breach. The right to terminate this Agreement in advance applicable to the observant party under this Agreement shall
be the right other than any other remedies available to it, and such termination shall not exempt the defaulting party from any obligations
arising from the termination date of this Agreement, nor shall it exempt the defaulting party from the liability for compensation for
the losses caused to the observant party due to its breach of this Agreement or other transaction documents.


 




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13.1.4
When calculating the loss of the Buyer, in addition to the loss and cost incurred by the Buyer itself, the loss should also include the
difference between the actual value of the Target Company’s equity caused by the Seller’s misrepresentation or concealment
(if there is no such misrepresentation or concealment) and the value in Appraisal and Consultation Report issued by Beijing North
Asia Asset Assessment Firm (Special General Partnership) with Jul. 31, 2022 as the base date, and the resulting impairment of the equity
value of the Target Company held by the Buyer. The Buyer has the right to directly deduct from the transaction consideration payable
to the Seller and treat it as the corresponding reduction of transaction consideration. If this Agreement is terminated for the Seller’s
reason, the Seller shall pay interest to the Buyer in accordance with the latest 1-year loan market quotation rate published by the National
Interbank Funding Center when returning the transfer consideration to the Buyer, in addition to assuming the liability for breach of
contract as agreed herein.


 


13.2
Termination of the agreement


 


13.2.1
Unless otherwise specified in this Agreement, this Agreement may be terminated at any time under the following circumstances:


 


A.
It is terminated in accordance with this Agreement;


 


B.
(i) The Buyer finds that any promises or warranties of the Seller contained in any transaction document are untrue or inaccurate; (ii)
The Buyer believes that the Seller fails to comply with any promise or agreement or obligation in any transaction document to be complied
with, and fails to correct it within [10] days after the Buyer’s written notice; If the Buyer chooses not to terminate the agreement,
it will not affect the Buyer to claim for compensation for the Seller’s breach of the obligations and liabilities under this Agreement.


 


C.
If any government department issues any laws and regulations, or issues any order, decree or ruling, or takes any other legal action
to restrict, prevent or otherwise prohibit the transactions under this Agreement, or make the transactions under this Agreement illegal
or impossible to be completed, and such order, decree, ruling or other legal action is final and cannot be applied for reconsideration,
prosecution or appeal, either party of this Agreement may terminate this Agreement by giving a written notice to the other party;


 




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D.
The Seller and the Buyer agree to terminate the agreement in writing through consultation.


 


13.2.2
Effectiveness after the termination of agreement


 


A.
If this Agreement is terminated according to the provisions of this agreement, this Agreement will be announced to be terminated, and
nothing in this Agreement will exempt either party from liability for breach of contract under this Agreement.


 


B
If the Buyer has paid the transfer price, the Seller shall also return the transfer price to the Buyer and bear the capital occupation
fee at an annual rate of 10% to the Buyer; If alteration registration in administration for industry and commerce has been completed,
the Seller shall complete the equity return to the Buyer by repurchasing the equity. At that time, both parties shall issue the corresponding
documents according to the requirements of the relevant departments of administration for industry and commerce and administrative authorities.
The taxes arising from the repurchase of equity shall be borne by the defaulting party. If both parties have completed the closing in
accordance with this Agreement, both parties shall carry out the closing reversal after the Seller returns the transfer consideration
(stock) and the liability for breach of contract (if any) to the Buyer.


 


XIV.
Modification


 


14.1
Unless otherwise agreed in this Agreement, this Agreement can only be revised, supplemented and modified by both parties in writing.


 




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XV.
Notice


 


15.1
Any notice related to this Agreement shall be written in Chinese and delivered by specially-assigned personnel, fax, registered mail
or express mail from a courier company recognized by both parties. The notice shall become effective upon receipt and shall be deemed
to have been received at the following time: (1) If delivered by specially-assigned personnel, registered mail or express mail, at the
time of delivery; Or (2) if delivered by fax, at the time of transmission. In either case, if the notice is delivered outside working
hours, it shall be deemed to have been received at the beginning of working hours on the next working day.


 


15.2
For the purpose of Article 15.1, the contact information of the Parties is as follows:


 


The
Seller: Beijing Kanghuayuan Medicine Information Consulting Co., Ltd.


 


To:
LIU Fengming


 


Address:


 


Tel:


 


E-mail:


 


The
Buyer: Shineco Life Science Research Co., Ltd.


 


To:
REN Zheming


 


Address:


 


Tel:


 


E-mail:


 


Target
Company: Changzhou Biowin Pharmaceutical Co., Ltd.


 


To:
LIU Fengming


 


Address:


 


Tel:


 


E-mail:


 


15.3
Both parties may change the above address or contact information in good faith from time to time. As long as one party sends a change
notice to the other party according to the above address or contact information and the other party gives a corresponding response, the
changed address or fax No. will replace the above address and contact information.


 




    	 	 	19



    	



    

 


XVI.
Secrecy


 


16.1
The matters involved in this Agreement and this transaction, any and all contacts and negotiations between the Parties on this Agreement
and this transaction, and the existence of this Agreement are confidential matters. Except for disclosure to relevant laws and other
professional advisers who have confidentiality obligations to the Parties or disclosure in accordance with the requirements of relevant
laws, relevant rules of any relevant stock exchange, and requirements of a government agency or other competent authority having jurisdiction
over either party hereto, either party shall not disclose any such confidential matters to any third party other than the signatory of
this Agreement without the prior written consent of the other party.


 


XVII.
Tax bearing


 


17.1
Taxes, costs and expenses related to this transaction shall be paid and borne by both parties in accordance with the agreement or respective
applicable laws.


 


XVIII.
Severability


 


18.1
If any terms or other provisions of the Agreement are deemed as invalid, illegal or unenforceable according to any laws and regulations
or public policies, all other terms and provisions of this agreement shall remain in full force and effect as long as the economic or
legal substance of the proposed transaction under the Agreement is not seriously adversely affected by any party in any form. If any
terms or other provisions are deemed as invalid, illegal or unenforceable, the Parties of this Agreement shall negotiate in good faith
to revise this Agreement, and achieve the original intention of the Parties as nearly as possible in an acceptable manner, so as to complete
the transaction proposed in this Agreement as far as possible according to the original plan.


 




    	 	 	20



    	



    

 


XIX.
Governing Law


 


This
Agreement shall be governed by and construed in accordance with the Chinese laws.


 


XX.
Litigation and arbitration


 


20.1
Any dispute, controversy or claim arising from or in connection with this Agreement, the transactions to be conducted under this Agreement,
or the interpretation, breach, termination or effectiveness of this Agreement shall be settled by both parties through negotiation. The
negotiation shall begin immediately after one party delivers a written notice to the other party. In case of failure of the dispute to
be resolved within [15] days after the date of service of such written notice, then upon the request of either party to the dispute,
the dispute shall be submitted to Beijing Arbitration Commission for arbitration. The place of arbitration shall be [Beijing, China].
The arbitration fees (including but not limited to the fees of arbitration institutions, arbitrators, lawyers, appraisal fees, evaluation
fees, preservation fees, etc.) shall be borne by the losing party.


 


20.2
When any dispute arises or is under litigation, both parties shall continue to perform their respective obligations under this Agreement
and have the right to exercise their respective rights under this Agreement, except for the dispute items.


 


XXI.
Language text and effectiveness of the agreement


 


21.1
This Agreement is written in Chinese. If this Agreement is translated into English or both of Chinese and English, in case of any conflict
between the English interpretation and the Chinese interpretation, the Chinese interpretation shall prevail.


 


21.2
This Agreement shall come into force on the date when the legal representatives or authorized representatives of the Parties sign (or
affix their seals) and affix their official seals.


 


21.2
The original of this Agreement is made in [six] copies, with each party holding two copies, and the Target Company shall keep two copies
for equity change and other procedures, each of which has the same legal effect. In case of equity change, when the competent government
department requires to issue a simple or compliant text, the Parties shall make it in accordance with the spirit of this Agreement. In
case of any inconsistency with this Agreement, this Agreement shall prevail.


 


(No
text below)


 




    	 	 	21



    	



    

 


 


(No
text on this page - signature page of Stock Purchase Agreement)


 


In
witness whereof, the duly authorized representatives of the Parties hereto have signed this Agreement on the date stated on the head
of this Agreement.


 


The
Seller:


 


Beijing
Kanghuayuan Medicine Information Consulting Co., Ltd.


 


Legal
representative or authorized representative (signature/signature or seal):





	/s/Fengming
    Liu	 


 


The
Buyer:


 


Shineco
Life Science Research Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Jennifer
    Zhan	 



 


Target
Company:


 


Changzhou
Biowin Pharmaceutical Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Fengming
    Liu	 



 




    	 	 	22



    	



    

 


☐
Annex I Resolution of the Shareholders’ Meeting of the Target Company


 


Resolution
of the Shareholders’ Meeting of Changzhou Biowin


 


Pharmaceutical
Co., Ltd.


 


According
to the relevant provisions of the Company Law and the Articles of Association of the Company, the shareholders’ meeting
of the Company was hosted by and convened on Oct. 19, 2022. 5 shareholders should attend the meeting, and 1 shareholder actually attended
the meeting, representing 63.7% of the voting rights of the Company. The Supervisor Zhou Wei attended the meeting, which is in accordance
with the legal procedures.


 


The
shareholders present unanimously adopted the following resolutions through negotiation:


 


It
was agreed that Shineco Life Science Research Co., Ltd. would purchase at least 51% of the Company’s equity.


 


It
was agreed to give up the preemptive right of the equity involved in the equity acquisition of Shineco Life Science Research Co., Ltd.


 


It
was agreed to elect LIU Fengming as the shareholder representative and the Company’s representative to participate in the business
negotiation and decision-making in the acquisition process, and agreed that Beijing Kanghuayuan Medicine Information Consulting Co.,
Ltd. would transfer 51% of the Company’s shares to Shineco Life Science Research Co., Ltd. through internal consensus.


 


The
shareholders attending the meeting made a special statement that the Company had no proxy shareholders except the existing registered
shareholders.


 


Signature
of shareholders attending the meeting for confirmation:


 


Beijing
Kanghuayuan Medicine Information Consulting Co., Ltd. (sealed)


 


Oct.
19, 2022


 


☐
Annex II List of Main Assets Involved by the Target
Company


 


“Commercially
Sensitive Information Omitted”


 




    	 	 	23



    	



    

 


☐
Annex III Transfer (Closing) Confirmation


 


In
accordance with the Stock Purchase Agreement signed between the Seller and the Buyer and the Target Company on 10/21/2022, for
the closing matters of this transaction, the Seller and the Buyer agree and confirm that: The Closing Date of this transaction is 12/30/2022.


 


This
Confirmation is signed by the Seller and the Buyer on 12/30/2022.


 


The
Seller:


 


Beijing
Kanghuayuan Medicine Information Consulting Co., Ltd.


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Fengming
    Liu	 


 


The
Buyer:


 


Shineco
Life Science Research Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Jennifer
    Zuhan	


 


Target
Company:


 


Changzhou
Biowin Pharmaceutical Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Fengming
    Liu	


 




    	 	 	24



    	



    

 


☐
Annex IV Supplementary Representations, Promises or
Warranties of the Seller


 


Unless
otherwise agreed in this Annex, the definitions in this Agreement have the same meanings in this Annex.


 


The
Seller hereby jointly makes the following representations, promises or warranties to the Buyer, in order to promote the Buyer to enter
into this Agreement, and as a precondition for its entry into this Agreement. Such statements and warranties are true and accurate on
the date of signing this Agreement and the Closing Date:


 


1.
Company composition


 


the
Company is a limited liability company duly incorporated, validly surviving and in good standing under the laws of China.


 


2.
Authority, authorization and qualification of the Company


 


The
Company has full rights, capabilities and powers, and has legally obtained all necessary licenses, permits, authorizations, qualifications,
approvals, registrations and records (collectively referred to as “government authorizations”) for the following matters:
(i) It owns, uses, operates, leases, licenses and disposes of its property and assets (tangible or intangible); (ii) it lawfully carries
on the business in progress; (iii) It is legally established and validly survives in accordance with the law, and these governmental
authorizations are still valid. The Company has not violated its government authorization. The Company has not applied to the relevant
government departments for ending or changing the business it is operating.


 


3.
Conflict free


 


The
signing, delivery and performance of the transaction documents by the Seller will not:


 


(a)
violate or conflict with the provisions of the Articles of Association of the Seller/Target Company;


 


(b)
violate or conflict with any laws and regulations, government authorization or government directives applicable to the Company, and/or
any one or more of the Seller or any of its assets, properties or businesses (or events that may cause significant adverse effects due
to any laws and regulations, government authorization or government directives);


 




    	 	 	25



    	



    

 


(c)
conflict with or cause breach of any agreement, contract, license, permit, approval or other binding document or arrangement to which
any one or more of the Seller is a party or more or by which any of its business, assets or property is bound or affected, or constitute
a default under such document or arrangement, or require any consent or authorization according to such document or arrangement, or grant
others the right to terminate, modify, accelerate the payment for, suspend, revoke or cancel such documents or arrangements, or cause
any encumbrance to be placed on the equity or assets of the Company pursuant to such documents or arrangements.


 


4.
Registered capital


 


(a)
The Seller will pay its subscribed registered capital in full in accordance with the provisions of this contract and the accounting rules
before the closing. The Seller has legal, effective and complete ownership of all the equity of the Company without any encumbrance.


 


(b)
The Company does not have any options, warrants, convertible securities or other rights, agreements, arrangements or promises of any
nature relating to the equity or obligating the Seller to sell the equity of the Company or any other interest in the Company. The Company
is not obligated to repurchase, redeem, or otherwise purchase any equity. The Company has no obligation to provide financing, investment
(whether by way of loan, capital contribution or otherwise) or repayment to any other subject. Except for the disclosed information,
the Seller has not made any promise to sell, transfer, donate, pledge or dispose of any equity of the Company to any third party orally
or in writing.


 


c)
After completing the transactions proposed under this Agreement, the Buyer shall have legal, valid, complete and exclusive ownership
for the Company’s equity held without any encumbrance and obligation for additional investment in the Company under the law or
contract.


 




    	 	 	26



    	



    

 


5.
Company records


 


All
the resolutions of the shareholders’ meeting (shareholders) and the board of directors (executive director) and other company records
provided by the Seller to the Buyer are true and comprehensive, and accurately reflect the resolutions and deliberations of the shareholders’
meeting (shareholders) and the board of directors (executive director). The Company’s records are kept in accordance with good
industry standards. All documents provided to the Buyer contain the latest company records.


 


6.
Financial data, books and records


 


(a)
The Seller has delivered to the Buyer (i) all capital verification reports and all relevant notes and schedules of the Company issued
by accountants employed by the Seller since the establishment date of the Company; (ii) Audited balance sheets, relevant audited income
statements and cash flow statements for [3] financial years as of Jul. 31, 2022, together with all relevant notes and schedules; (iii)
The unaudited balance sheet of the Company, relevant income statement and cash flow statement as of the last day of the last quarter
(if any) before the Closing Date (the “Financial Statement Date”), together with all relevant notes and schedules ((i), (ii)
and (iii) above are collectively referred to as the “Financial Statements”). The Financial Statements (i) have been prepared
in accordance with the books of account and other financial records of the Company; (ii) fairly reflect the financial position and operating
results of the Company as of the statement date or during the corresponding period; (iii) have been prepared in accordance with the accounting
standards and the consistency principle consistent with the previous practice of the Company; and (iv) have included all adjustments
necessary to fairly reflect the financial position and operating results of the Company as of the statement date or during the corresponding
period.


 


(b)
book of accounts and other financial records of the Company shall: (i) reflect all income and expenditure items and all assets and liabilities
required to be reflected according to the accounting standards applicable to the basis consistent with the past practices of the Company;
(ii) be complete and correct in all material respects and not contain or reflect any material inaccuracy or inconsistency; and (iii)
be prepared according to good business and accounting practice.


 




    	 	 	27



    	



    

 


(c)
The Company or the target equity, and the Company’s assets have not suffered any events that cause their value to be depreciated
from the Financial Statement Date to the Closing Date, unless otherwise specified in this Agreement, or the Seller has disclosed to the
Buyer in writing and obtained the Buyer’s written consent.


 


7.
No undisclosed liabilities and obligations


 


The
Company has no liabilities or obligations (including but not limited to loans to shareholders or loans to third parties).


 


8.
Government authorization and legitimacy


 


The
Company has obtained all the approvals, permits, licenses and all government authorizations necessary to operate its current business,
and such approvals, permits, licenses and all government authorizations are effective from the signing date to the Closing Date (including
the date). The Company has not violated the provisions of such governmental authorization in any material respect. All such governmental
authorizations are still valid, have not expired, and have not been revoked or terminated in the foreseeable future. Such governmental
authorization will not be revoked, terminated or invalidated due to any transaction contemplated by this Agreement.


 


9.
Unsecured


 


The
Company has not provided any form of guarantee (including but not limited to mortgage, pledge and guarantee) to any subject, or set any
encumbrance or make such commitment on any of its assets for the benefit of any other subject.


 




    	 	 	28



    	



    

 


10.
Appeal


 


(a)
There is no appeal filed by or against the Company in any government department, or which affects any assets or property or business
of the Company, or the legality or enforceability of this Agreement and the transactions hereunder. Neither the Company nor any of its
businesses, assets or properties is bound by any government directive that will have or has had a material adverse effect, nor by any
government directive that may affect the legality, effectiveness or enforceability of this Agreement or affect the completion of the
transactions contemplated by this Agreement.


 


(b)
There is no litigation, arbitration, administrative procedure, inquiry, government investigation, dissolution or liquidation procedure,
or other judicial proceedings in progress, pending, with the Company as a party, or against the Company’s assets or the transactions
under this Agreement that can affect the normal operation of the Company; There are no claims for compensation or reimbursement against
or threatened against the Company which are sufficient to affect the normal operation of the Company.


 


(c)
There are no lawsuits, arbitration proceedings or governmental and administrative investigations, penalties and other procedures filed
by the Company that can affect the normal operation of the Company.


 


11.
Law abiding


 


(a)
The Company conducts business within its approved business scope and domicile in accordance with all laws and regulations and government
directives applicable to it or any of its properties or assets or business, and the Company does not violate any such laws and regulations
or government directives.


 


(b)
The Seller has complied with all statutory requirements for capital increase under applicable laws and regulations.


 


12.
Contract


 


(a)
The Seller has disclosed all material contracts without any omission, modification or update.


 


(b)
There are no currently effective agreements, contracts or arrangements to which the Company is a party:


 


i.
Agreements, contracts or other arrangements that violate applicable laws and regulations;


 




    	 	 	29



    	



    

 


ii.
Agreements, contracts or other arrangements that will harm the interests of the buyer;


 


iii.
If there is such agreement, contract or other arrangement, the Buyer’s performance of the terms of this Agreement will lead to
the release of any obligation of a third party to the Company, or create any right for a third party, or cause the Company to breach
any contract, or cause the Company to lose any interest, right, license or assume more obligations;


 


iv.
Any agreement, contract or other arrangement that is contrary to the principle of fair dealing and has a serious adverse impact on the
Company;


 


v.
Any agreement, contract or other arrangement involving joint venture, partnership or profit sharing (or loss sharing);


 


(d)
All major contracts shall: (i) be legally established, binding upon all parties to such contract and have full legal effect; And (ii)
come into force after the completion of the transactions contemplated by this Agreement.


 


(e)
The Company does not have any behavior seriously violating any agreement, contract or other arrangement and sufficient to affect the
normal operation of the Company; There are no circumstances or events that cause such agreements, contracts or other arrangements to
be breached by the Company.


 


(f)
The Company has not received any notice of termination, cancellation of any such agreement, contract or other arrangement, or breach
of its terms.


 


(g)
There is no contract or agreement granting any priority to any entity to purchase the Company’s major assets, properties, equity,
or other rights or interests (excluding purchases made in the normal course of business consistent with past practices).


 




    	 	 	30



    	



    

 


13.
Intellectual properties


 


(a)
The Company legally owns intellectual property rights.


 


(b)
There is no ownership dispute over the Company’s intellectual property rights.


 


14.
Real estate


 


The
Company does not own any real estate.


 


15.
Major assets


 


(a)
The Seller has disclosed all properties and assets (“assets”) used or intended to be used by the Company in its business
or otherwise occupied or used by it, as well as the ownership of the Company.


 


(b)
The Company legally owns or has the right to use these assets. The Company has the legal, valid and exclusive ownership and use right
of all the assets.


 


(c)
The Company has always maintained its assets in accordance with good industry practices. Except for wear and tear during normal use,
all assets are in good operating and maintenance conditions and are suitable for their current and planned use.


 


(d)
The Company’s ownership of the assets, or the right to use and lease the rental assets, will not incur any penalty or other adverse
consequences due to the completion of the transactions under this Agreement, including but not limited to any increase in costs caused
or incurred by the completion of the transactions contemplated by this Agreement.


 


16.
Labor and social insurance


 


Before
the closing, the Company will deal with labor relations in accordance with this Agreement and existing labor laws and regulations, including
but not limited to laws and regulations on labor contracts, working hours, labor protection, minimum wages, overtime wages and dismissal
compensation, social insurance and housing provident fund. There are no unresolved collective labor disputes, slowdowns or stoppages,
and there are no unresolved labor complaints against the Company.


 




    	 	 	31



    	



    

 


17.
No foreign investment


 


The
company has no foreign investment.


 


18.
No related transactions


 


(a)
The Seller and the Company’s shareholders, key employees or directors, as well as the related parties of such shareholders, key
employees or directors, do not have any direct or indirect interests in any competitors, suppliers or customers of the Company; do not
own, directly or indirectly, all or part of any tangible or intangible property that has been used to carry on the business of the Company,
or have any other interest in it; do not owe any debt to the Company.


 


(b)
The Company has not had any transaction with any related party.


 


19.
Taxable item


 


(a)
The Company has declared and paid all taxes on time and in full amount in accordance with applicable laws and regulations. All required
tax certificates and reports related to the Company’s taxes and fees have been submitted on time;


 


(b)
All taxes required to be shown on such tax certificates and reports or otherwise due have been paid on time;


 


(c)
All tax certificates and reports have been submitted to the Buyer and shall be true, correct and complete in all material respects, and
the taxable amount, applicable tax rate and allowable tax deductible items recorded on the tax certificates and reports shall have no
false and material errors;


 


(d)
All tax departments shall not formally or informally propose the adjustment to the tax certificate, and as known by the Company, there
shall be no basis for such adjustment;


 


(e)
There shall be no pending or potential litigation or proceedings against the Company about the assessment, penalty or taxes and fees
collection;


 


(f)
the Company shall not carry out transactions or conclude contracts for the purpose of illegal tax avoidance.


 


(g)
The Company discloses to the Buyer that the tax preferential treatment it has enjoyed or will enjoy is true, effective, legal and compliant.


 




    	 	 	32



    	



    

 


20.
Accounts receivable and payable


 


All
accounts receivable disclosed to the Buyer are enforceable transactions that reflect fairness, good faith and truth, are generated in
the normal business activities of the Company, and have been properly reflected in the Company’s financial reports and other company
records disclosed to the Buyer. No customer or supplier expects the Company to make other payments to them except those arising from
the Company’s normal business activities. All accounts payable disclosed to the Buyer are generated in normal business activities.


 


21.
Customers and suppliers


 


The
customers and suppliers disclosed by the Seller to the Buyer are true and effective.


 


22.
Anti-corruption


 


Neither
the Seller nor the Seller has made or ever made any monetary payment or other benefit payment to any third party (including but not limited
to government departments, state-owned enterprises or entities related to government departments and state-owned enterprises) related
to the Company’s business not in line with the anti-corruption law, anti-unfair competition law or other applicable laws and regulations
of China or any other relevant region, or promised to make such payment.


 


23.
Health, safety and environment


 


The
Company and its affiliated companies, its predecessor or former affiliated companies have complied with all laws, regulations and policy
requirements related to health, safety and environment, and have not received any notice of violation of the above laws, regulations
and policy requirements or any notice of relevant legal liability. The Company has obtained all permits related to its business and complied
with the provisions or attached conditions of these permits.


 




    	 	 	33



    	



    

 


24.
Full disclosure


 


The
information related to the Company or business or related parties of the Company has been fully disclosed to the Buyer according to the
Buyer’s requirements, does not contain any untrue representations of important facts, and does not omit any important facts that
are necessary to avoid misleading such statements.


 


This
Supplementary Representations, Promises or Warranties of the Seller is signed on 10/21, 2022.


 


The
Seller:


 


Beijing
Kanghuayuan Medicine Information Consulting Co., Ltd.


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Fengming
    Liu	 


 


The
Buyer:


 


Shineco
Life Science Research Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Jennifer
    Zhan	 


 


Target
Company:


 


Changzhou
Biowin Pharmaceutical Co., Ltd. (official seal)


 


Legal
representative or authorized representative (signature/signature or seal):


	/s/Fengming
    Liu	 


 




    	34