|FIRST AMENDMENT TO
LEASE



THIS FIRST AMENDMENT TO LEASE dated
as of March 20, 2000 by and between 82 Cambridge Street Associates LLC, as (Landlord),
and Palomar Medical Technologies, Inc., as Tenant.


WHEREAS, Landlord and Tenant
executed that certain Lease dated June 17, 1999, relating to certain premises at 82
Cambridge Street, Burlington, Massachusetts, the Commencement Date of which was August
26, 1999.


WHEREAS, Landlord and Tenant desire
to amend the square footage of Tenants demised area, and;


WHEREAS, Landlord and Tenant have
agreed to amend the rent structure of the Lease accordingly, and;


WHEREAS, Landlord and Tenant have
agreed to make certain changes to the Lease as provided below.


NOW THEREFORE, for good and valuable
consideration, the receipt and sufficiency of which is hereby acknowledged, Landlord and
Tenant agree as follows:
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|1. |  | Effective
as of the date hereof, the first floor space consists of 42,905 rentable square
              foot and the lower level space consists of 545 rentable square foot.
|-- |  | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|2. |  | Rent:
 Effective as of the date hereof, the rent section of Exhibit B to the
              Lease is hereby deleted and Exhibit A attached shall be submitted
therefore. In all other respects, the Lease is hereby ratified, confirmed and approved
and shall continue in full force and effect, except as herein expressly modified.
|-- |  | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|IN WITNESS WHEREOF, the parties
hereto have executed these presents as a sealed instrument as of the day and year first
above written.


WITNESS the execution hereof under
seal as of the date first above set written.
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|                                    |                                   
|----------------------------------- | ----------------------------------
|LANDLORD:                           | TENANT:                           
|82 Cambridge Street Associates, LLC | Palomar Medical Technologies, Inc.
|                                    |                                   
|By: /s/  Bruce Gorsky               | By: /s/Paul S. Weiner             
|Its: Manager                       | Its:Treasurer                    

|EXHIBIT A
|-----------

|             |                                
|------------ | -------------------------------
|DATES        | RENT PER MONTH                 
|             |                                
|Years 1-5    | $863,550.00                    
|             |                                
|Years 6-10   | $949,360.00                    
|             |                                
|OPTION:      |                                
|             |                                
|Years  11-15 | * (See Extension Term in Lease)

|The foregoing calculations are based
on the following bases: (1) the rent for years 1-5 is computed at $20.00 per rentable
square foot of first floor space and $10.00 per rentable square foot for below grade
space; and (ii) the rent for years 6-10 is computed at $22.00 per rentable square foot
space and $10.00 per rentable square foot for below grade space.
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