U.S. flagAn official website of the United States government
                    Here's how you know **Official websites use .gov**
                            
                            A **.gov** website belongs to an official government organization in the United States.
 **Secure .gov websites use HTTPS**
                            
                            A **lock** (                            
                              A locked padlock                                                      
                            
                            ) or **https://** means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.


Menu Agricultural Research Service
						
                    U.S. DEPARTMENT OF AGRICULTURE
 close



Research
                Research Home
                            National Programs
                            Research Projects
                            Scientific Manuscripts
                            International Engagement
                            Scientific Software/Models
                            Databases and Datasets
                            Office of Scientific Quality Review
            Media
                News & Features
                            Multimedia
                            Briefing Room
                            Down on the Farm
                            Press Room
                            Science in Your Shopping Cart
                            Scientific Discoveries
                            Tellus
                            Under the Microscope
            About ARS
                About ARS Home
                            Staff Directory
                            Labs and Research Centers (Map)
                            Headquarter Offices
                            Organizational Chart
                            Employee Services (REE Employees Only)
                            Office of Outreach, Diversity, and Equal Opportunity
            Work With Us
                Work With Us Home
                            ARS Vacancies at USAJOBS
                            Careers at ARS Information
                            Scientific Collaborations
                            Extramural Agreements
                            1890 Faculty Research Sabbatical ProgramSearch small
                    Search
            
            ARS Home
                                About ARS
                                Contact Us




ARS Home Research Publications at this Location





- ARS National Programs
- Search for a scientific manuscript
- Search for a research project
- ARS Software
- Programs and Projects
- Collaborations
- Subjects of Investigation
- Publications

Title:   Author  item
                                            Brockmeier, Susanitem
                                            Lager, Kellyitem
                                            Bolin, Steven

                                                         - *Steve*item
                                            Palmer, Mitchellitem
                                            Rimler, Richard

                                                         - *Rick*
  Submitted to: International Pig Veterinary Society (IPVS)
                                    Publication Type: Proceedings
                                    Publication Acceptance Date: 6/6/2000
                                    Publication  Date: 9/15/2000
                                    Citation: N/AInterpretive Summary:
                                Technical Abstract: Respiratory disease in pigs is arguably the most important health concern for swine producers today.  Pneumonia in swine is often multifactorial, caused by infection with multiple pathogens as well as environmental and management factors.  Porcine reproductive and respiratory syndrome virus (PRRSV) is a widely disseminated pathogen of swine associated with  reproductive and respiratory disease.  There is experimental and clinical data that PRRSV exacerbates the adverse effects of other pathogens. Bordetella bronchiseptica is also commonly found in swine and is considered a cause of bronchopneumonia and atrophic rhinitis.  Infection with B. bronchiseptica predisposes pigs to disease with pathogens such as toxigenic Pasteurella multocida and Streptococcus suis.  P. multocida is a common secondary invader in respiratory diseases of pigs.  Since all three of these agents are common pathogens of pigs, the purpose of this study was to odetermine whether there was interaction among these agents in causing respiratory disease.  These experiments demonstrated that infection with PRRSV predisposed pigs to pulmonary infection with B. bronchiseptica. PRRSV by itself did not predispose to infection with P. multocida.  Prior infection with B. bronchiseptica enabled P. multocida to colonize the upper respiratory tract but did not affect the ability of these agents to gain access to the lower respiratory tract.  When there was prior infection with both B. bronchiseptica and PRRSV, P. multocida was able to gain access to the lung.  All three of these agents are commonly found in swine herds, thus simultaneous infection with PRRSV and B. bronchiseptica may result in severe inhibition of resistance to secondary respiratory pathogens such as P. multocida.


Return to top


Connect with ARS Sign up


ARS Home
                            USDA.gov
                            Plain Writing
                            Policies & Links
                            Civil Rights Statements
                            FOIA
                            Accessibility Statement
                            Privacy Policy
                            Non-Discrimination Statement
                            Quality of Information
                            USA.gov
                            WhiteHouse.gov