Federal Register / Vol. 60, No. 243 / Tuesday, December 19, 1995 / Notices 65321

area of environmental sciences, health

effects and life sciences, and medical

applications. Major program research

emphasis is placed on characterization

of human and microbial genomes,

structural biology, cellular and

molecular biology, global climate

change, improved technology for

cleanup of DOE contaminated sites,

advanced imaging technologies, and

molecular nuclear medicine. With the

explosion of nucleic acid and amino

acid sequence data that stems from

genome projects, there is an immediate

need for greatly improved experimental

and computational approaches for

protein structure determination. To help

meet this need, and in support of

diverse missions of DOE, OHER is

initiating a new program in

computational structural biology. The

purpose of this program is to support

research that will enhance

understanding of structure-function

relationships in biological

macromolecules. These relationships

are very important for diverse

applications in biotechnology, including

development of drugs for diseases, new

and improved biomaterials, design of

enzymes for effective and efficient

removal of environmental contaminants,

and the development and conversion of

bio-mass for fuels. In particular,

research applications that integrate

existing software tools in novel ways

and/or develop new computational

strategies to exploit databases of

macromolecular structural information

towards furthering our understanding of

the relationships between sequence and

structure are of particular interest to the

program at this time. This includes the

goals of predicting the structure and

function of newly discovered gene

sequences and the prediction or design

of the chemical properties and

architectural arrangement of proteins or

nucleic acids needed for a particular

functional application. Examples of

existing approaches that fall into this

category are knowledge-based or

molecular extension methods (e.g.,

homology model building or multiple

sequence alignment), ab initio folding

(finding structures that fit sequences)

and the development of tools to assign

existing or new sequences to specific

structures (e.g., finding sequences that

fit structures through threading or

inverse folding algorithms). Attention

should be also focussed on the problem

of negative design, the identification of

aspects of a sequence that precludes its

fitting a known structure. More

generally, the integration and joint

utilization of the growing body of

sequence, structural and physical

information is an area that offers new

opportunities that are of interest to the

program. Studies that rigorously

compare existing tools and/or exploit

the latest advances in multiple

approaches (in algorithms, simulation,

modeling and graphical representation/

visualization) or that include the

development of new computational and

visualization techniques for application

to the prediction of protein and nucleic

acid structure and the exploitation of

structure to predict function, will also

be considered particularly responsive.

Collaborative projects with two to five

principal investigators, of

complementary expertise and each with

independent funding, aimed at

achieving a synergistic effect in

improving structure prediction accuracy

through such activities as evaluation of

different potential functions, the

development of shared code, or an

integrated attack on a set of problems in

an area of prediction or in testing

current modeling techniques are also

encouraged. Funds for such projects

would be comparable to individual

awards, but could be used to nucleate a

larger group effort.

DATES: Formal applications submitted in

response to this notice must be received

by 4:30 p.m., E.D.T., April 25, 1996, to

be accepted for a June merit review and

to permit timely consideration of award

in Fiscal Year 1996.

ADDRESSES: Formal applications

referencing Program Notice 96–03

should be forwarded to: U.S.

Department of Energy, Office of Energy

Research, Grants and Contracts

Division, ER–64, 19901 Germantown

Road, Germantown, Maryland 20874–

1290, ATTN: Program Notice 96–03.

The same address as above must be used

when submitting applications by U.S.

Postal Service Express Mail, any

commercial mail delivery service, or

hand carried by the applicant.

FOR FURTHER INFORMATION CONTACT: Dr.

Matesh N. Varma, Office of Health and

Environmental Research, ER–73, U.S.

Department of Energy, 19901

Germantown Road, Germantown,

Maryland 20874–1290, telephone: (301)

903–3209, Fax: (301) 903–0567, (E-mail:

matesh.varma@mailgw.er.doe.gov).

SUPPLEMENTARY INFORMATION: Before

preparing a formal application, potential

applicants must submit a brief

preapplication in accordance with 10

CFR 600.10(d)(2), which consists of two

to three pages of narrative describing

research objectives and methods of

accomplishment. These will be

reviewed relative to the scope and

research needs for the computational

structural biology program.

Preapplications referencing Program

Notice 96–03 should be received by

January 23, 1996, and sent to Dr. Matesh

N. Varma, Office of Health and

Environmental Research, 19901

Germantown Road, Germantown,

Maryland 20874–1290, (301) 903–3209.

Telephone and fax numbers and e-mail

addresses are required to be part of the

preapplication. A response to the

preapplication discussing potential

relevance of a formal application will be

communicated by February 20, 1996. It

is anticipated that approximately $2.0

million will be available for grant

awards during Fiscal Year 1996

contingent upon availability of funds.

We expect to award several grants in

this area of research up to a few

hundred thousand dollars per year.

Information about development,

submission, and the selection process,

and other polices and procedures may

be found in 10 CFR Part 605, and in the

Application Guide for the Office of

Energy Research Financial Assistance

Program. The Application Guide is

available from the U.S. Department of

Energy, Office of Health and

Environmental, ER–73, 19901

Germantown Road, Germantown,

Maryland 20874–1290. Telephone

requests may be made by calling (301)

903–5349. Electronic access to ER’s

Financial Assistance Guide is possible

via the Internet using the following Email address: http://www.er.doe.gov/

The Catalog of Federal Domestic

Assistance Number for this program is

81.049, and the solicitation control number is

ERFAP 10 CFR Part 605.

Issued in Washington, D.C. on December

11, 1995.

D. D. Mayhew,

Associate Director, Office of Resource

Management, Office of Energy Research.

[FR Doc. 95–30749 Filed 12–18–95; 8:45 am]

BILLING CODE 6450–01–P

ENVIRONMENTAL PROTECTION

AGENCY

[FRL–5398–3]

Agency Information Collection

Activities Under OMB Review

AGENCY: Environmental Protection

Agency (EPA).

ACTION: Notice.

SUMMARY: In compliance with the

Paperwork Reduction Act (44 U.S.C.

3501 et seq.), this notice announces that

the Information Collection Request (ICR)

abstracted below has been forwarded to

the Office of Management and Budget

(OMB) for review and comment. The
65322 Federal Register / Vol. 60, No. 243 / Tuesday, December 19, 1995 / Notices

ICR describes the nature of the

information collection and its expected

cost and burden; where appropriate, it

includes the actual data collection

instrument.

DATES: Comments must be submitted on

or before January 18, 1996.

FOR FURTHER INFORMATION OR A COPY

CALL: Sandy Farmer at EPA, (202) 260–

2740, and refer to EPA ICR No. 1100.08.

SUPPLEMENTARY INFORMATION:

Title: National Emission Standards for

Hazardous Air Pollutant (OMB Control

No. 2060–0191; EPA ICR No. 1100.08).

‘‘This is a request for extension of a

currently approved collection.’’

Abstract: On December 15, 1989

pursuant to Section 112 of the Clean Air

Act as amended in 1977 (42 U.S.C.

1857), the Environmental Protection

Agency promulgated NESHAPs to

control Radionuclide emissions from

several source categories. The

regulations were published in 54 FR

51653, and are codified at 40 CFR

Subparts B, H, I, K, R, T, and W, and

imposes the following radionuclide

dose and emission standards:

Subpart B—Underground Uranium

Mines

10 mrem/yr

Subpart H—Department of Energy

10 mrem/yr, 20 pci/m 2-s

Subpart I—Non-DOE not licensed by

NRC

10 mrem/yr, 3 mrem/yr; iodine

Subpart I—Licensed by NRC

10 mrem/yr, 3 mrem/yr iodine

Subpart K—Elemental Phosphorous

2 curies/yr

Subpart R—Phosphogypsum Stacks

20 pci/m 2-s

Subparts T and W—Uranium Mill

Tailings Piles

20 pci/m 2-s

Information collected is used by EPA

to ensure that public health continues to

be protected from the hazards of

airborne radionuclides by compliance

with these. If the information were not

collected, it is unlikely that violation of

the standards would be identified and

no corrective action would be initiated

to bring the facilities back into

compliance. Compliance is

demonstrated through emission testing

and/or dose calculation. Results are

submitted to EPA Regional office

annually or when required for

verification of compliance and

maintained for a period of 5 years.

An agency may not conduct or

sponsor, and a person is not required to

respond to, a collection of information

unless it displays a currently valid OMB

control number. The OMB control

numbers for EPA’s regulations are listed

in 40 CFR Part 9 and 48 CFR Chapter

15. The Federal Register Notice required

under 5 CFR 1320.8(d), soliciting

comments on this collection of

information was published on 08/25/95

(FR Doc. 95–21169).

Burden Statement: The annual public

reporting and Record keeping burden

for this collection of information is

estimated to average 31 hours per

response. Burden means the total time,

effort, or financial resources expended

by persons to generate, maintain, retain,

or disclose or provide information to or

for a Federal agency. This includes the

time needed to review instructions;

develop, acquire, install, and utilize

technology and systems for the purposes

of collecting, validating, and verifying

information, processing and

maintaining information, and disclosing

and providing information; adjust the

existing ways to comply with any

previously applicable instructions and

requirements; train personnel to be able

to respond to a collection of

information; search data sources;

complete and review the collection of

information; and transmit or otherwise

disclose the information.

Respondents/Affected Entities: 6112.

Estimated Number of Respondents:

412.

Frequency of Responses: Annually or

less than annually.

Estimated Total Annual Hour Burden:

188,708 hours.

Estimated Total Annualized Cost

Burden: $1,758,559.

Send comments on the Agency’s need

for this information, the accuracy of the

provided burden estimates, and any

suggested methods for minimizing

respondent burden, including through

the use of automated collection

techniques to the following addresses.

Please refer to EPA ICR No. 1100.08 and

OMB Control No. 2060–0191 in any

correspondence.

Ms. Sandy Farmer, U.S. Environmental

Protection Agency, OPPE Regulatory

Information Division (2136), 401 M

Street, SW., Washington, DC 20460.

and

Office of Information and Regulatory

Affairs, Office of Management and

Budget, Attention: Desk Officer for

EPA, 725 17th Street, NW.,

Washington, DC 20503.

Dated: December 5, 1995.

Joseph Retzer,

Director, Regulatory Information Division.

[FR Doc. 95–30793 Filed 12–18–95; 8:45 am]

BILLING CODE 6560–50–M

[FRL–5398–2]

Agency Information Collection

Activities Under OMB Review; EPA

Indoor Environmental Quality

Questionnaire

AGENCY: Environmental Protection

Agency (EPA).

ACTION: Notice.

SUMMARY: In compliance with the

Paperwork Reduction Act (44 U.S.C.

3501 et seq.), this notice announces that

the Information Collection Request (ICR)

for ‘‘EPA Indoor Environmental Quality

Questionnaire’’ abstracted below has

been forwarded to the Office of

Management and Budget (OMB) for

review and comment. The ICR describes

the nature of the information collection

and its expected cost and burden; where

appropriate, it includes the actual data

collection instrument.

DATES: Comments must be submitted on

or before January 18, 1996.

FOR FURTHER INFORMATION OR A COPY

CALL: Sandy Farmer at EPA, (202) 260–

2740, and refer to EPA ICR No. 1619.02.

SUPPLEMENTARY INFORMATION:

Title: EPA Indoor Environmental

Quality Survey (OMB Control No. 2060–

0244; EPA ICR No. 1619.02). This is a

request for an extension of a currently

approved collection.

Abstract: The Indoor Environmental

Quality Questionnaire is a component of

the EPA Building Assessment Survey

and Evaluation (BASE) program. In this

program, EPA is conducting an indoor

air quality (IAQ) study of 100–200 large

commercial and public office buildings.

The purpose of this tudy is to develop

a national baseline assessment of the

indoor air in such buildings. The

activities EPA will conduct under this

survey include Indoor Environmental

Quality Questionnaire, building

inspections, interviews with building

maintenance workers, environmental

measurements (e.g., ventilation rates,

concentrations of indoor air pollutants),

and other quantitative and qualitative

assessments. By conducting this

research, EPA will begin to be able to

assess the key building parameters that

affect IAQ and the incidence of certain

IAQ-related health and comfort

problems. The Indoor Environmental

Questionnaire is a voluntary

questionnaire asking for information

pertaining to work station

characteristics, working conditions,

exposure to pollutants, health and wellbeing, and stress. Data from the Indoor

Environmental Questionnaire will be

used to compare the measured building

parameters and health effects.