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ARS Home Plains Area Houston, Texas Children's Nutrition Research Center Research





- Chandler, Laurence - Larry
- 2023
- 2022
- 2021
- 2020
- Human Nutrition (107)

Research Project: Acute Effects of Sedentary Behaviors on Cardiometabolic Risk in Latino Youth **Location:
                            Children's Nutrition Research Center** 2021 Annual Report **Objectives**
                                

Objective: Examine the acute effects of sedentary behaviors on energy metabolism and cardiometabolic health in Latino adolescents, after adjusting diet. **Approach**
                                

Researchers will utilize whole-room calorimetry to examine the effects of an acute bout of sedentary behaviors on cardiometabolic outcomes (glucose, insulin, lipids, arterial stiffness) and energy metabolism (energy expenditure, substrate utilization) in Latino adolescents (12-16 years old) with obesity (BMI% '95th) as compared to non-Latino white adolecents (12-16 years old) with obesity (BMI% '95th). Findings from this study will increase our understanding of the contributions of sedentary behaviors to the development of cardiometabolic diseases in high-risk youth. This information will inform future behavioral interventions aimed at reducing sedentariness to reduce disease risk and address health disparities in Latino youth. **Progress Report**
                                

This year our research project was submitted to the Institutional Review Board and received initial approval. Further progress was made toward Objective 1 through the development of recruitment materials. We created recruitment flyers and a list of potentially eligible participants using the Children's Nutrition Research Center volunteer database. To train staff in preparation for Objective 1 activities, we met with various teams at the Children's Nutrition Research Center to begin coordinating research activities for this study. We developed a protocol manual to further establish procedures and to facilitate training. This protocol manual includes training on the protection of human subjects, informed consent, protocols for measuring anthropometrics, collecting blood specimens, and the careful handling of sensitive data. Our protocol for blood specimen collection and analyses is still being developed. Once this protocol is finalized, staff will receive additional training. In preparation for data collection, all surveys for data collection have been developed and tested in REDCap, our data management software. **Accomplishments**


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