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 Mycotoxin Prevention and Applied Microbiology Research: Peoria, IL
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ARS Home Midwest Area Peoria, Illinois National Center for Agricultural Utilization Research Mycotoxin Prevention and Applied Microbiology Research Research





- Hao, Guixia
- Food Safety, (Animal and Plant Products) (108)

Research Project: **Location:
                            Mycotoxin Prevention and Applied Microbiology Research** Project Number: 5010-11420-001-006-T
                        
                        Project Type: Trust Fund Cooperative Agreement Start Date: Oct 1, 2021
                        
                        End Date: Sep 30, 2025 **Objective:**
                        
                        Objective: Develop an endophyte-based delivery system for double-stranded RNA (dsRNA) to control Fusarium mycotoxin production and mitigate associated corn crop losses. **Approach:**
                        
                        We propose to develop an innovative method to deliver dsRNAs efficiently and continuously to maintain the RNAi effect in planta using an endophyte delivery system.   We will utilize a corn endophyte to continuously produce and supply RNAi signals to combat Fusarium pathogens and mycotoxin contamination. 

We will introduce dsRNA constructs already developed by ARS into a corn endophyte, inoculate variable corn varieties with the transgenic endophyte, and then determine the RNAi silencing efficacy targeting these critical mycotoxin biosynthesis genes of Fusarium graminearum and Fusarium verticillioides.


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