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                                                                   Exhibit 10.14


               Employment Agreement with Sean M. Johnston, Ph.D.

[LETTERHEAD OF MAGAININ PHARMACEUTICALS INC.]

November 30, 1998

Sean M. Johnston, Ph.D.

Dear Sean:

I am pleased to offer you the position of Vice President, Manufacturing with
Magainin Pharmaceuticals Inc., reporting to the Roy Levitt, Chief Operating
Officer. Your base salary will be $10,833.33 per month ($130,000/year).
Contingent upon your acceptance of this offer, it is expected that the
Compensation Committee of the Board of Directors will grant to you at its next
meeting options to purchase 30,000 shares of Magainin Common Stock, exercisable
at the fair market value underlying common stock on the date of such meeting.
These options will have a term of 10 years and vest at the rate of 25% per year.
As with all Magainin options, the grant will be subject to execution of a stock
option agreement in the form specified by the Compensation Committee.

Additionally, you will be eligible for merit increases, cash bonuses, and such
further stock options grants as may be awarded at the annual discretion of the
Company's Board of Directors.

Upon the commencement of your employment with the Company, you will be expected
to execute the Company's Drug Free Workplace Policy, Proprietary Information
Agreement, Policy Statement on Securities Trading by Magainin Personnel, and
Corporate Governance - Conflict of Interest Policy, each in the form previously
provided to you. Magainin may have already provided you with certain of its
confidential business or scientific information, which it expects you to keep
confidential, and to use only to further Magainin's legitimate business
interests. Just as Magainin expects you to keep confidential its business or
scientific information, Magainin also expects you to honor your obligations to
your former employers with respect to maintaining the confidentiality of their
business or scientific information.

If your employment is terminated without cause, as defined in the Stock Option
Plan, you will receive your monthly base salary for one (1) year following the
date of termination, or for such shorter period until you have secured full-time
employment elsewhere.

You will be eligible for twenty (20) days vacation per year. Vacation accrues
proportionate to months employed. Employees are encouraged to take their
vacations yearly. However, up to five (5) days of unused vacation time can be
carried over into next year with supervisor approval. In addition, you will be
eligible for the benefits package available to all employees. Enclosed is a
summary of the benefits.
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All the terms and conditions of this Agreement shall be binding upon and inure
to the benefit and be enforceable by the respective heirs, representatives,
successors (including any successor as a result of a merger or similar
reorganization) and assigns of the parties hereto, except that your duties and
responsibilities hereunder are of a personal nature and shall not be assignable
in whole or in part by you.

We look forward to your joining us at Magainin Pharmaceuticals Inc.  Please
indicate your acceptance of this offer, which is for at will employment, by your
signature below.  This offer of employment will remain in effect until Tuesday,
December 8, 1998.  We have agreed that your start date will be Monday, January
4, 1999, at 8:30 AM.  Please do not hesitate to speak with me concerning any
questions you may have.

                                         Sincerely,

                                         /s/ Michael R. Dougherty
                                         ------------------------
                                         Michael R. Dougherty
                                         President and Chief Executive Officer