Exhibit
10.25


 


Third
Amendment to Transaction Documents


 


This
Third Amendment to the Transaction (this “Amendment”) is effective as of October 14, 2022 (“Effective Date”),
by and between Puritan Partners LLC, a New York limited liability company (“Puritan Partners”) and Curative Biotechnology,
Inc., a Florida corporation (the “Company”), having its principal place of business at 1825 NW Corporate Blvd., Suite
110 Boca Raton, FL 33431, each a “Party” and collectively the “Parties”. Capitalized terms used
herein without definition shall have the meanings ascribed to them in the Securities Purchase Agreement, dated as of March 2, 2022, as
amended, entered between the Parties (the “Securities Purchase Agreement”)


 


Recitals


 


WHEREAS,
pursuant to the Transaction Documents, Puritan Partners purchased a 12.5% Original Issue Discount Senior Secured Note in the principal
amount of $1,142,857.14 due March 2, 2023 (the “Note”) and was issued a common stock purchase warrant to purchase 22,857,143
shares of the common stock at $0.0001 exercise price (the “Warrants”);


 


WHEREAS, Puritan
Partners and Company are parties to the Transaction Documents, which were previously amended on August 18, 2022 and October 2, 2022
and the parties now desire to further amend the respective Transaction Documents in accordance with the terms of this
Amendment.


 


NOW,
THEREFORE, in consideration of the following and other consideration, the receipt of which is hereby acknowledged, the parties agree
as follows:


 


		a)	Monthly
                                            Redemption Date. The definition of “Monthly Redemption Date” set forth in Section
1 of the Note is deleted in its entirety and hereby replaced with the following:






 


“Monthly
Redemption Date” means the second of each month, commencing immediately upon November 2, 2022, and terminating upon the full redemption of this Note. Provided however that upon completion of a Qualified
Offering, the entire outstanding balance of the Note will be due and payable at closing of the Qualified Offering.


 





	 	b)
  	Monthly Redemption Amount. The definition of “Monthly Redemption Amount” set forth in Section 1 of the Note is deleted in its entirety and hereby replaced with the following:



 





“Monthly
Redemption Amount” means, as to a Monthly Redemption, one fifth of the original principal amount at 110% of such principal
amount, plus accrued but unpaid interest, liquidated damages and any other amounts then owing to the Holder in respect of this Note.




 





	 	c)	The interest on the Note that is due and payable on October 2, 2022, shall
instead be due and payable on the earlier of (i) November 2, 2022 and (ii) the closing of the Qualified Offering.
	 	 	 
	 	d)	In further consideration for extending by one month the straight-line
amortization payment requirement under the Note, the Company agrees that (i) the number of shares underlying the Warrant shall be increased
from 24,761,905 shares to 26,666,667 shares and (ii) upon the closing of Company’s offering being registered pursuant to the S-1
Registration Statement (Registration. No. 333-264339), the outstanding principal balance, along with any accrued interest, fees or costs,
will be repaid, in full pursuant to either the Optional Redemption provisions contained in Section 5(a) of the Note or the Mandatory Prepayment
provisions contained in Section 5(d) of the Note, as the case may be.



 






    	 



     


    

 


Each
of the undersigned has caused this Amendment to be duly executed and delivered as of the date first written above and will become effective
as of the Effective Date.


 


	 	CURATIVE BIOTECHNOLOGY, INC.
	 	 	 
	 	By:	 
	 	Name:	Richard
    Garr                  
	 	Title:	Chief
    Executive Officer


 


	 	Puritan Partners LLC
	 	 	 
	 	By:	 
	 	Name:	Richard
    Smithline
	 	Title:	Managing
    Member