|FOURTH AMENDMENT TO
LEASE


THIS
FOURTH AMENDMENT TO LEASE (the Amendment) is made and
entered into effective as of February 27, 2009 (the Effective Date) by
and betweenNORTHLAND CAMBRIDGE STREET LLC, a Delaware limited liability company
(Landlord) andPALOMAR MEDICAL TECHNOLOGIES, INC., a Delaware
corporation (Tenant).



RECITALS
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|A. | Landlord and Tenant are parties to that certain Commercial Lease dated June 17,
          1999 (the Original Lease) by and between 82 Cambridge Street
          Associates, LLC and Tenant, as amended by that certain First Amendment to Lease
          dated as of March 20, 2000 (the First Amendment), as further
          amended by that certain Second Amendment to Lease dated as of January 18, 2006
          (the Second Amendment), as further amended by that certain
          Third Amendment to Lease dated as of July 30, 2007 (the Third
          Amendment). The Original Lease as amended by the First Amendment, the
          Second Amendment, the Third Amendment and this Fourth Amendment is herein
          referred to as the Lease.
|-- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|B. | Pursuant to the Original Lease, as amended to date, Tenant currently leases
          certain office space consisting of (i) 55,450 rentable square feet in the
          building located at 82 Cambridge Street, Burlington, Massachusetts (the
          82 Cambridge Street Premises) and 13,600 rentable square feet
          in the building located at 80 Cambridge Street, Burlington, Massachusetts (the
          80 Cambridge Street Premises). Collectively, the 82
          Cambridge Street Premises and 80 Cambridge Street Premises shall be referred to
          herein as the Premises.
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|C. | The Term of the Lease will expire on August 31, 2009.
|-- | -----------------------------------------------------

|D. | Tenant has requested that Landlord extend the term of the Lease to August 31,
          2010 (the Extended Term) and that the Lease be appropriately
          amended, and Landlord is willing to do the same on the following terms and
          conditions.
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|NOW,
THEREFORE, in consideration of the above recitals which by this reference are
incorporated herein, the mutual covenants and conditions contained herein and other
valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
Landlord and Tenant agree as follows:
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|1. |  | Term; No Extension Option.
|-- |  | --------------------------

|1.01. |  | Effective
as of the Effective Date, the Term of the Lease shall be extended to August 31, 2010,
which date shall be the expiration date of                the Extended Term (the Expiration
Date).
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|1.02. |  | Tenant
hereby acknowledges and agrees that all rights of Tenant set forth in the
               Lease to extend the term of the Lease, including without limitation
Exhibit B of                the Original Lease, have expired without being exercised and
thus are of no                further force or effect.
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|2. |  | Monthly Base Rent.
|-- |  | ------------------

|2.01. |  | Effective
as of September 1, 2009, the Base Rent for the Premises shall be $135,558.33 per
month (i.e. $121,391.67 per month for the                82 Cambridge Street Premises and
$14,166.67 per month for the 80 Cambridge                Street Premises).
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|
|

|2.02. |  | Tenant
hereby acknowledges and agrees that the obligations of Tenant under the
               Lease shall be separate and independent covenants and agreements, that
Base Rent                and all other amounts due under the Lease (collectively,
               Rent) shall continue to be payable in all events and
that the                obligations of Tenant under the Lease shall continue unaffected,
unless the                requirement to pay or perform the same shall have been
terminated pursuant to an                express provision of the Lease.
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|3. |  | Holdover.
|-- |  | ---------

|3.01. |  | Section
23 of the Original Lease notwithstanding, if Tenant fails to surrender                all
or any part of the Premises at the termination of this Lease in the
               condition required pursuant to the Lease (including without limitation
Section                27 of the Original Lease), occupancy of the Premises after
termination shall be                that of a tenancy at sufferance. Tenants
occupancy shall be subject to all                the terms and provisions of this Lease,
and Tenant shall pay an amount (on a per                month basis without reduction for
partial months during the holdover) equal to                200% of the sum of the Base
Rent and additional rent (including without                limitation Real Estate Taxes
and Operating Costs) due for the period immediately                preceding the
holdover. No holdover by Tenant or payment by Tenant after the                termination
of this Lease shall be construed to extend the Term or prevent                Landlord
from immediate recovery of possession of the Premises by summary
               proceedings or otherwise. If Landlord is unable to deliver possession of
the                Premises to a new tenant or to perform improvements for a new tenant
as a result                of Tenants holdover, Tenant shall (i) be liable for all
damages that                Landlord suffers from the holdover, including without
limitation all                consequential damages arising therefrom, and (ii) indemnify
and hold landlord                harmless against and from all liabilities, obligations,
damages, penalties,                claims, actions, costs, charges and expenses,
including, without limitation,                reasonable attorneys fees and other
professional fees (if and to the                extent permitted by law), which may be
imposed upon, incurred by or asserted                against Landlord by any third party
and arising out of or in connection with                such holdover.
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|4. |  | Miscellaneous.
|-- |  | --------------

|4.01. |  | Effective
as of the Effective Date, Sections 37 and 38 of the Original Lease                shall
be of no further force or effect.
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|4.02. |  | This
Amendment sets forth the entire agreement between the parties with respect
               to the matters set forth herein. There have been no additional oral or
written                representations or agreements. Under no circumstances shall Tenant
be entitled                to any Rent abatement, improvement allowance, leasehold
improvements, or other                work to the Premises or any similar economic
incentives that may have been                provided Tenant in connection with entering
into the Lease, unless specifically                set forth in the Original Lease (as
amended by the First Amendment, Second                Amendment and Third Amendment) or
this Amendment.
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|4.03. |  | Except
as herein modified or amended, the provisions, conditions and terms of                the
Original Lease (as amended by the First Amendment, Second Amendment and
               Third Amendment) shall remain unchanged and in full force and effect.
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|4.04. |  | In
the case of any inconsistency between the provisions of the Original Lease
               (as amended by the First Amendment, Second Amendment and Third Amendment)
and                this Amendment, the provisions of this Amendment shall govern and
control.
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|
|

|4.05. |  | Neither
Landlord nor Tenant shall be bound by this Amendment until both Landlord
               and Tenant have executed the same.
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|4.06. |  | The
capitalized terms used in this Amendment shall have the same definitions as
               set forth in the Original Lease (as amended by the First Amendment, Second
               Amendment and Third Amendment) to the extent that such capitalized terms
are                defined therein and not redefined in this Amendment.
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|4.07. |  | Tenant
hereby represents to Landlord that Tenant has dealt with no broker in
               connection with this Amendment. Tenant agrees to indemnify and hold
Landlord,                its trustees, members, principals, beneficiaries, partners,
officers, directors,                employees, mortgagee(s) and agents, and the
respective principals and members of                any such agents harmless from all
claims of any brokers claiming to have                represented Tenant in connection
with this Amendment.
|----- |  | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

|4.08. |  | Each
signatory of this Amendment represents hereby that he or she has the
               authority to execute and deliver the same on behalf of the party hereto
for                which such signatory is acting.
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|[signatures on
following page]



IN
WITNESS WHEREOF, Landlord and Tenant have duly executed this Fourth Amendment to Lease
as of the day and year first above written.
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|                          |                                                                     
|------------------------- | --------------------------------------------------------------------
|WITNESS/ATTEST:           | LANDLORD:                                                           
|                          |                                                                     
|/s/ Leika Cooke           | NORTHLAND CAMBRIDGE STREET LLC, a Delaware limited liability company
|                          |                                                                     
|Name (print): Leika Cooke | By:/s/ Steven P. Rosenthal                                          
|                          | Name: Steven P. Rosenthal                                           
|                          | Title: CEO, President and Treasurer                                 

|                              |                                                            
|----------------------------- | -----------------------------------------------------------
|WITNESS/ATTEST:               | TENANT:                                                    
|                              |                                                            
|/s/ Eleanor Chemlen           | PALOMAR MEDICAL TECHNOLOGIES, INC., a  Delaware corporation
|                              |                                                            
|Name (print): Eleanor Chemlen | By: /s/ Paul S. Weiner                                     
|                              | Name: Paul S. Weiner                                       
|                              | Title: CFO                                                 

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