**Exhibit10.50**

**AMENDMENT**

**THIS AMENDMENT** is made as ofMarch 1, 2007 and amends the Employment Agreement dated as of September 26,2000 as amended through February 13, 2006 (the “Employment Agreement”) between **DENDRITE INTERNATIONAL, INC.** (“Dendrite”) and **NATASHA GIORDANO** (“Employee”).  Unless defined in this Amendment, capitalizedterms used in this Amendment will have the meaning set forth in the EmploymentAgreement.

WHEREAS, the Company and the Employee are parties tothe Employment Agreement and wish to amend the Employment Agreement; and

WHEREAS, the Compensation Committee of the Board hasdetermined it to be in the best interests of the Company and its shareholdersfor the Company to commit to certain executives of the Company facing potentialexcise tax liability, that certain payments shall be made in the event suchliability exists upon the consummation of any Change of Control;

NOW, THEREFORE, in consideration of the premises andmutual covenants contained in this Amendment, the Company and the Employeeagree as follows:

1.             Section 27(f) ofthe Employment Agreement is restated in its entirety to provide as follows:

“(f)          Notwithstanding anything else hereinto the contrary, in the event that the Company’s certified public accountants(or another of the “big four” certified public accounting firm, if the Company’scertified public accountants may not provide such service due to independenceor other considerations) (the “Accountants”) determine that any actual orpotential payment or distribution by the Company to or for the benefit of theEmployee (whether paid, payable, distributed or distributable to the Employee,whether under this Agreement or otherwise) (a “Payment”) would likely subjectthe Employee to the imposition of an excise tax under Section 4999 of the Code(or any similar successor provision) (“Section 4999”), then the Company shallpay to the Employee an amount (the “Tax Gross-Up Payment”), to be calculated bythe Accountants, designed and calculated to fully negate the tax impact of any excisetax and any potential interest or penalties related thereto and any expensesincurred attributable to any claim contest or notice of alleged deficiency oralleged underpayment imposed (or to be imposed) upon the Employee as a resultof Section 4999.  Any such Tax Gross-UpPayment will take into account the federal, state and local income, employmentand excise tax consequences of the Tax Gross-Up Payment, including theadditional impact of Section 4999 on the Tax Gross-Up Payment itself.  The Employee shall be deemed to pay federal,state and local taxes at the highest marginal rate of taxation for theapplicable calendar year.  The estimatedTax Gross-Up Payment due the Employee with respect to any Payment shall be paidto the Employee in a lump sum not later than thirty (30) business days aftersuch Payment is provided to the Employee. In the event that the Tax Gross-Up Payment is less than the amountactually due to the Employee under this Section 27(f) the amount of any suchshortfall, plus applicable additional interest or penalties related thereto andany expenses incurred attributable to any claim contest or notice of allegeddeficiency or alleged underpayment, shall be paid to the Employee within ten(10) days after the existence of the shortfall is discovered.  In the event the Tax Gross-Up Payment is more

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than the amountactually due the Employee under this Section 27(f), the Employee shall repaythe amount of such overpayment to the Company within a reasonable time afterthe overpayment is discovered.”

2.             Exceptas expressly modified by this Amendment, all of the terms and conditions of theEmployment Agreement shall remain in full force and effect.

**IN WITNESS WHEREOF,**theparties have signed this Amendment as of the first date written above.
|            | **DENDRITE INTERNATIONAL, INC.** |
|------------|----------------------------------|
| ** ** | ** **                       |
| ** ** | ** **                       |
| ** ** | /s/ Christine  Pellizzari        |
| ** ** | Name:                            | Christine Pellizzari |
|       | Title:                           | Senior Vice President, General Counsel and Secretary |
|       |                             |
|       |                             |
|       | /s/ Natasha  Giordano            |
|       | Natasha Giordano                 |

** **

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