**Exhibit10.58**

**AMENDMENT**

**THIS AMENDMENT** is made as ofOctober 23, 2006 and amends the Employment Agreement dated as of November 21,2005, as amended as of February 13, 2006 (collectively the “EmploymentAgreement”), between **DENDRITE INTERNATIONAL,INC.**(“Dendrite”) and **JEFFREY BAIRSTOW**(“Employee”).  Unless defined in the Amendment, capitalizedterms used in this Amendment will have the meaning set forth in the EmploymentAgreement.

WHEREAS,the Company and the Employee are parties to the Employment Agreement and wishto amend the Employment Agreement; and

WHEREAS,the Company considers it essential to the best interests of its shareholders tofoster the continuous employment of key management;

NOWTHEREFORE, in consideration of the premises and mutual covenants contained inthis Amendment, the Company and the Employee agree as follows:

1.             Section 4(b) of the EmploymentAgreement is deleted and replaced as follows:

If your employmenthereunder is terminated by Dendrite for any reason other than death, Cause (asdefined in Exhibit A), or Disability (as defined in Exhibit A), you shall beentitled to receive severance payments of your monthly base salary for 12months following your employment termination (calculated at the rate of basesalary then being paid to you as of the date of termination) and your FinalAnnual Target Bonus (as defined below Section 4(g)).  The severance payments to be paid to youunder this Section 4(b) shall be referred to herein as the “Severance Payment.”  The Severance Payment shall be paid to you intwelve consecutive equal monthly payments commencing in the payroll periodfollowing the date you sign the separation agreement described in Section 4(d)below.  No interest shall accrue or bepayable on or with respect to any Severance Payment.  In the event of a termination of youremployment described in this Section 4(b), you shall be provided continued “COBRA”coverage pursuant to Sections 601 et seq. of ERISA under Dendrite’s grouphealth plan.  During the period which youreceive the Severance Payment, your cost of COBRA coverage shall be the same asthe amount paid by employees of Dendrite for the same coverage under Dendrite’sgroup health plan.  Notwithstanding theforegoing, in the event you become re-employed with another employer and becomeeligible to receive health coverage from such employer, the payment of COBRAcoverage by Dendrite as described herein shall cease.  You agree to notify Dendrite of any full-timeemployment that you begin while receiving the Severance Payment.

2.             A new Section 4(g) is added to theEmployment Agreement as follows:

Final Annual Target Bonus means the annual target bonus established foryou in the fiscal year in which your employment terminates, or, if the annualtarget bonus has not been established for you in such fiscal year, then theannual target bonus for the prior fiscal year shall be used.

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3.             Exceptas expressly modified by this Amendment, all of the terms and conditions of theEmployment Agreement shall remain in full force and effect.

IN WITNESSWHEREOF, the parties have signed this Amendment as of the first date writtenabove.
|            | **DENDRITE  INTERNATIONAL, INC.** |
|------------|-----------------------------------|
| ** ** | ** **                        |
| ** ** | ** **                        |
|       | By:                               |   | /s/ Christine A. Pellizzari |
|       | Name:                             | Christine A.  Pellizzari |
|       | Title:                            | Sr. Vice  President, General Counsel |
|       |                              | and Secretary |
|       | Date:                             | November       ,  2006 |
|       |                              |   |
|       |                              |   |
|       |                              | /s/ Jeffrey  Bairstow |
|       | Name:                             | Jeffrey Bairstow |
|       | Date:                             | November       ,  2006 |

** **

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