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Exhibit 12.1

Certification by the Chief Executive OfficerOf
3SBio Inc.Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

I, Jing Lou, certify that:

|1. | I have reviewed this annual report on Form 20-F of 3SBio
      Inc. for the fiscal year ended December 31, 2012;                                                                                                                                                                                                                                      
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|2. | Based on my knowledge, this report does not contain any
      untrue statement of a material fact or omit to state a material fact
      necessary to make the statements made, in light of the circumstances under
      which such statements were made, not misleading with respect to the period
      covered by this report;                    
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|3. | Based on my knowledge, the consolidated financial
      statements, and other financial information included in this report,
      fairly present in all material respects the financial condition, results
      of operations and cash flows of the company as of, and for, the periods
      presented in this report;                             
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|4. | The companys other certifying officer and I are
      responsible for establishing and maintaining disclosure controls and
      procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and
      internal control over financial reporting (as defined in Exchange Act
      Rules 13a-15(f) and 15d-15(f)) for the company and have:
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|   | (a)                                                                                                                                                                                                                                                                                                                                                   
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|   | (b)                                                                                                                                                                                                                                                                                                                                                   
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|   | (c)                                                                                                                                                                                                                                                                                                                                                   
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|   | (d)                                                                                                                                                                                                                                                                                                                                                   
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|5. | The companys other certifying officer and I have
      disclosed, based on our most recent evaluation of internal control over
      financial reporting, to the companys auditors and the audit committee of
      the companys board of directors (or persons performing the equivalent
      function):                                         
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|   | (a)                                                                                                                                                                                                                                                                                                                                                   
|   |                                                                                                                                                                                                                                                                                                                                                       
|   | (b)                                                                                                                                                                                                                                                                                                                                                   

Date: April 30, 2013

By: /s/ DR. JING
LOUName: Dr. Jing LouTitle: Chief Executive Officer

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