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|  ̈ | Registration statement pursuant to Section 12(b) or 12(g) of the Securities Exchange Act of 1934 |
|--------|-------------------------------------------------------------------------------------------------------|

| x | Annual report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 |
|---|-------------------------------------------------------------------------------------------|

|  ̈ | Transition report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 |
|--------|-----------------------------------------------------------------------------------------------|

|  ̈ | Shell company report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 |
|--------|--------------------------------------------------------------------------------------------------|

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| Title of Each Class                                                                                | Name of Each Exchange on Which Registered |
|----------------------------------------------------------------------------------------------------|-------------------------------------------|
| American Depositary Shares, each representing seven ordinary shares, par value US$0.0001 per share |  The NASDAQ Stock Market LLC         |

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| ·   | Exhibit 4.8: |
|--------------------|--------------|

| (1)   | The description of the Appendices, appearing at the end of Exhibit 4.8 “English Translation of the Contract Form”, is revised. |
|-----------------|--------------------------------------------------------------------------------------------------------------------------------------------|

| (2)   | An Index to Exhibit 4.8 Appendices Public Documents (“4.8 Index”), and the English translation copy of each of the Exhibit 4.8 Appendices Public Documents (as listed and labeled in 4.8 Index) up to and including Ex 4.8.51  are added to and as a part of the publicly filed Exhibit 4.8. |
|-----------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|

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|   | PART III |
|--------|----------|

| ExhibitNumber |   | Description of Exhibits                                                                                                                                                                                                                                                                                   |
|---------------|--------|-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
| 1.1           |   | Amended and Restated Memorandum of Association of 3SBio Inc. (incorporated by reference to Exhibit 3.1 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                                    |
|          |   |
| 1.2           |   | Amended and Restated Articles of Association of 3SBio Inc. (incorporated by reference to Exhibit 3.2 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                                      |
|          |   |
| 2.1           |   | Form of Share Certificate of 3SBio Inc. (incorporated by reference to Exhibit 4.1 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                                                         |
|          |   |
| 2.2           |   | Form of Deposit Agreement, including Form of ADR, of 3SBio Inc. (incorporated by reference to Exhibit 4.2 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                                 |
|          |   |
| 4.1           |   | 2006 Stock Plan adopted by 3SBio Inc., dated as of September 5, 2006 (incorporated by reference to Exhibit 10.1 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                           |
|          |   |
| 4.2**         |   | First Amendment to 2006 Stock Plan                                                                                                                                                                                                                                                                        |
|          |   |
| 4.3**         |   | 2010 Equity Incentive Plan                                                                                                                                                                                                                                                                                |
|          |   |
| 4.4           |   | Form Purchase Contract for FCS between Shenyang Sunshine Pharmaceutical Company Limited and Shanghai Weike Biochemical Reagent Co., Ltd. (incorporated by reference to Exhibit 4.2 from our annual report on Form 20-F for the year ended December 31, 2008, filed with the Commission on April 21, 2009) |

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| 4.5**  |   | Form Purchase Agreement for BPT-6 culture medium between Shenyang Sunshine Pharmaceutical Company Limited and Invitrogen Trading (Shanghai) Company Limited, dated May 13, 2009 (portions of this exhibit have been omitted and filed separately with the Commission pursuant to a request for confidential treatment.)                                                                                                                                                                                                                                             |
|--------|--------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|   |   |
| 4.6    |   | Form of Distribution Agreement (incorporated by reference to Exhibit 10.15 from our F-1 registration statement (File No. 333-140099), as amended, initially filed with the Commission on January 19, 2007)                                                                                                                                                                                                                                                                                                                                                               |
|   |   |
| 4.7#   |   | Sanitary Piping System Contract between Shenyang Sunshine Pharmaceutical Company Limited and Shanghai Macroprocess Technology Co. Ltd., dated Mar.30, 2009 (portions of this exhibit have been omitted and filed separately with the Commission pursuant to a request for confidential treatment; and, this exhihit as filed in the Amendment No.1 amends and replaces the existing Exhibit 4.7 in the Original 20-F Filing in its entirety.)                                                                                                                            |
|   |   |
| 4.8##  |   | Installation Contract for the Core Cleanroom Area of the New Plant between Shenyang Sunshine Pharmaceutical Company Limited, and, Suntec Cleanroom & HVAC Engineering Co. Ltd. and Suntec (Suzhou) Cleanroom System Co. Ltd., dated  July 3, 2009 (portions of this exhibit have been omitted and filed separately with the Commission pursuant to a request for confidential treatment; and, this exhihit as filed in this Amendment No. 2 and Amendment No. 3 amends and replaces the existing Exhibit 4.8 in the Original 20-F Filing in its entirety.) |
|   |   |

| 8.1**  |                                                                                                                                                                                                                                                                                | List of Subsidiaries of 3SBio Inc.                                                                                                                                              |
|--------|------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
|   |                                                                                                                                                                                                                                                                                     |
| 11.1   |                                                                                                                                                                                                                                                                                | Code of Ethics (incorporated by reference to Exhibit 11.1 from our annual report on Form 20-F for the year ended December 31, 2006, filed with the Commission on June 29, 2007) |
|   |                                                                                                                                                                                                                                                                                     |
| 12.1** |                                                                                                                                                                                                                                                                                | CEO Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |
| 12.2** |                                                                                                                                                                                                                                                                                | CFO Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |
| 12.3*  |                                                                                                                                                                                                                                                                                | CEO Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |                                                                                                                                                                            |
| 12.4*  |                                                                                                                                                                                                                                                                                | CFO Certification Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |                                                                                                                                                                            |
| 13.1** |                                                                                                                                                                                                                                                                                | CEO Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |
| 13.2** |                                                                                                                                                                                                                                                                                | CFO Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |
| 13.3*  |                                                                                                                                                                                                                                                                                | CEO Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |                                                                                                                                                                            |
| 13.4*  |                                                                                                                                                                                                                                                                                | CFO Certification Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002                                                                                                     |
|   |                                                                                                                                                                                                                                                                                     |                                                                                                                                                                            |
| 15.1** |                                                                                                                                                                                                                                                                                | Consent of Ernst & Young Hua Ming                                                                                                                                           |
|   |                                                                                                                                                                                                                                                                                     |                                                                                                                                                                            |
| 15.2** |                                                                                                                                                                                                                                                                                     | Consent of KPMG                                                                                                                                                            |
| *      | Filed herewith.                                                                                                                                                                                                                                                                          |
| **     | Filed with the Original 20-F Filing.                                                                                                                                                                                                                                                     |
| #      | Filed in Amendment No.1                                                                                                                                                                                                                                                                  |
| ##     | Exhibit 4.8 Contract Form, 4.8 Index, and all documents listed and labelled in 4.8 Index from Ex 4.8.2 to Ex 4.8.51, inclusive, are filed in this Amendment No.2;  and all documents listed and labelled in 4.8 Index after Ex 4.8.52, inclusive, are filed in Amendment No.3. |

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|   | 3SBio Inc.                   |                    |
|--------|------------------------------|-------------------------|
|   |                         |                    |   |
|   | By:                          | /s/ Dr. Jing Lou   |   |
|   | Name:              | Dr. Jing Lou            |   |
|   | Title:                       | Chief Executive Officer |   |
|   |                         |                    |   |
|   | Date: November 3, 2011  |                    |

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