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|   | 1      | I      have reviewed this quarterly report on Form 10-QSB of Applied DNA      Sciences, Inc.;                                                                                                                                                                                                                                                                                                   |
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|   | 2.     | Based      on my knowledge, this quarterly report does not contain any untrue      statement of a material fact or omit to state a material fact necessary to      make the statements made, in light of the circumstances under which such      statements were made, not misleading with respect to the period covered by      this quarterly report;                                         |
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|   | 3.     | Based      on my knowledge, the financial statements, and other financial information      included in this quarterly report, fairly present in all material respects      the financial condition, results of operations and cash flows of the Small      Business Issuer as of, and for, the periods presented in this quarterly      report;                                                 |
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|   | 4.     | The      Small Business Issuer’s other certifying officers and I are responsible      for establishing and maintaining disclosure controls and procedures (as      defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal      control over financial reporting (as defined in Exchange Act Rules      13a-15(f) and 15d-15(f)) for the Small Business Issuer and      have: |
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|   |   | (a)                                                                                                                                                                                                                                                                                                                                                                                             | Designed      such disclosure controls and procedures, or caused such disclosure      controls and procedures to be designed under our supervision, to ensure      that material information relating to the small business issuer, including      its consolidated subsidiaries, is made known to us by others within those      entities, particularly during the period in which this report is being      prepared; |
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|   |   | (b)                                                                                                                                                                                                                                                                                                                                                                                             | [Omitted      pursuant to SEC Release No. 33-8238]; |
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|   |   | (c)                                                                                                                                                                                                                                                                                                                                                                                             | Evaluated      the effectiveness of the Small Business Issuer’s disclosure controls and      procedures and presented in this report our conclusions about the      effectiveness of the disclosure controls and procedures, as of the end of      the period covered by this report based on such evaluation;      and |
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|   |   | (d)                                                                                                                                                                                                                                                                                                                                                                                             | Disclosed      in this report any change in the Small Business Issuer’s internal control      over financial reporting that occurred during the small business issuer’s      most recent fiscal quarter (the small business issuer’s fourth fiscal      quarter in the case of an annual report) that has materially affected, or      is reasonably likely to materially affect, the small business issuer’s      internal control over financial reporting; and |
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|   | 5.     | The      Small Business Issuer’s other certifying officer(s) and I have disclosed,      based on our most recent evaluation of internal control over financial      reporting, to the small business issuer’s auditors of the small business      issuer’s board of directors (or persons performing the equivalent      functions):                                          |
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|   |   | (a)                                                                                                                                                                                                                                                                                                                                                                                             | All      significant deficiencies and material weaknesses in the design or      operation of internal control over financial reporting which are      reasonably likely to adversely affect the small business issuer’s ability      to record, process, summarize and report financial information;      and |
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|   |   | (b)                                                                                                                                                                                                                                                                                                                                                                                             | Any      fraud, whether or not material, that involves management or other      employees who have a significant role in the small business issuer’s      internal control over financialreporting. |

| Date:      May 15, 2008            |   |
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| /s/  JAMES A.    HAYWARD |   |
| James      A. Hayward              |   |
| Chief      Executive Officer       |   |