Specimen common stock certificate.



 Exhibit 4.1 

	
	 




 INCORPORATED UNDER THE LAWS 
 OF THE STATE OF DELAWARE 
 This Certifies that 
 is the record holder of 
 FULLY PAID AND NONASSESSABLE SHARES OF COMMON STOCK, $0.01 PAR VALUE, OF 
 MEDIDATA SOLUTIONS, INC. 
 transferable on the books of the Corporation in person or by duly authorized attorney upon surrender of this Certificate properly endorsed. This 
 Certificate is not valid until countersigned by the Transfer Agent and registered by the Registrar. 
 WITNESS the facsimile seal of the Corporation and the facsimile signatures of its duly authorized officers. 
 Dated: 
 SEE REVERSE FOR CERTAIN DEFINITIONS 
 CUSIP 58471A 10 5 
 SECRETARY 
 MEDIDATA SOLUTIONS, INC. 
 CORPORATE 
 SEAL 
 DELAWARE 
 2000 CHAIRMAN AND CHIEF EXECUTIVE OFFICER 
 COLORS SELECTED FOR PRINTING:
Intaglio prints in SC-7 dark blue. LOGO prints PMS 2738, PMS 375 and PMS 8420. 
 COLOR: This proof was printed from a digital
file or artwork on a graphics quality, color laser printer. It is a good representation of the color as it will appear on the final product. 
 However, it is not an exact color rendition, and the final printed product may appear slightly different from the proof due to the difference between the dyes and printing ink. 
 PLEASE INITIAL THE APPROPRIATE SELECTION FOR THIS PROOF: OK AS IS OK WITH CHANGES MAKE CHANGES AND SEND ANOTHER PROOF 
 MD 
 COUNTERSIGNED AND REGISTERED: 
 AMERICAN STOCK TRANSFER & TRUST COMPANY, LLC 
 (New York, NY) 
 TRANSFER AGENT AND REGISTRAR 
 BY: 
 AUTHORIZED SIGNATURE 
 AMERICAN BANK NOTE COMPANY 
 711 ARMSTRONG LANE 
 COLUMBIA, TENNESSEE 38401 
 (931) 388-3003 
 SALES: HOLLY GRONER 615-261-0610 
 PRODUCTION COORDINATOR: DENISE LITTLE 931-490-1706 
 PROOF OF: MAY 22, 2009 
 MEDIDATA SOLUTIONS, INC. 
 TSB 32460 FC 
 OPERATOR: AP 
 NEW 
 MEDIDATA SOLUTIONS, INC. 
 MEDIDATA 
 MEDIDATA SOLUTIONS, WORLD WIDE 







 

 
 For value received, hereby sell, assign and transfer unto 
 The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they 

were written out in full according to applicable laws or regulations: 
 TEN COM 
 TEN
ENT 
 JT TEN 
 – as tenants in common 
 – as tenants by the entireties 
 – as joint tenants with right 
 of survivorship and not as 
 tenants in common 
 UNIF GIFT MIN ACT– Custodian 
 (Cust) (Minor) 
 under Uniform Gifts to Minors 
 Act 
 (State)

 THE SIGNATURE TO THIS ASSIGNMENT MUST CORRESPOND WITH 
 THE NAME AS WRITTEN UPON THE FACE OF THE CERTIFICATE, IN 
 EVERY PARTICULAR, WITHOUT ALTERATION OR ENLARGEMENT, OR 
 ANY CHANGE
WHATEVER. 
 PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS INCLUDING POSTAL ZIP CODE OF ASSIGNEE 
 Shares 
 of
the common stock represented by the within Certificate, and do hereby irrevocably 
 constitute and appoint 
 PLEASE INSERT SOCIAL SECURITY OR OTHER 
 IDENTIFYING NUMBER OF ASSIGNEE 
 Attorney to transfer the said stock on the
books of the within-named Corporation with full power of 
 substitution in the premises. 
 Dated, 
 SIGNATURE(S) GUARANTEED: 
 THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR 
 INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS 
 AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE 
 GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15. 
 Additional
abbreviations may also be used though not in the above list. 
 NOTICE: 
 PLEASE INITIAL THE APPROPRIATE SELECTION FOR THIS PROOF: OK AS IS OK WITH CHANGES MAKE CHANGES AND SEND ANOTHER PROOF 
 AMERICAN BANK NOTE COMPANY 
 711 ARMSTRONG LANE 
 COLUMBIA, TENNESSEE 38401 
 (931) 388-3003 
 SALES: HOLLY GRONER 615-261-0610 
 PRODUCTION COORDINATOR: DENISE LITTLE 931-490-1706 
 PROOF OF: MAY 22, 2009 
 MEDIDATA SOLUTIONS, INC. 
 TSB 32460 BK 
 OPERATOR: AP 
 NEW