SIXTH LEASE EXTENSION AGREEMENT

                  THIS AGREEMENT  dated the 8th day of May, 1997, by and between
ICE  ASSOCIATES,  having an address of 15 Green Street,  Hackensack,  New Jersey
(hereinafter  called  "Landlord")  and DALTEX MEDICAL  SCIENCES,  INC. having an
address of 36-52 Kulick Road,  Fairfield,  New Jersey 07004 (hereinafter  called
"Tenant").

                        W I T N E S S E T H   T H A T:

                  WHEREAS,  Landlord and Tenant  entered into a Lease  Agreement
("Lease")  dated May 24, 1989 by which  Landlord  leased to Tenant  1,800 square
feet  located at 36-52  Kulick Road,  Fairfield,  New Jersey 07004  (hereinafter
"Initial Lease Agreement"); and

                  WHEREAS,  said  Initial  Lease  Agreement as extended by Lease
Extension  Agreement,  Second Lease Extension  Agreement,  Third Lease Extension
Agreement,  Fourth Lease Extension Agreement and Fifth Lease Extension Agreement
shall terminate on June 14, 1997; and

                  WHEREAS,  the  parties  hereto  wish to extend the term of the
initial  Lease  Agreement/Lease   Extension   Agreement/Second  Lease  Extension
Agreement/Third  Lease  Extension/Fourth  Lease  Extension/Fifth Lease Extension
under the same terms and  conditions  contained  therein,  with the exception of
those items enumerated below.

                  NOW,  THEREFORE,  in  consideration  of  the  mutual  promises
contained herein, the parties hereto agree as follows:

                  1. The Fifth Lease  Agreement is hereby  extended for one year
term commencing June 15, 1997 and terminating June 14, 1998 (hereinafter  "Sixth
Lease Extension Agreement").

                  2.  Tenant  has the right to cancel  this  Agreement  any time
after September 14, 1997 by giving the Landlord ninety (90) days written notice.

                  3. The Tenant  acknowledges that is presently in possession of
the leased  premises  and agrees  except as provided in the Lease as amended and
subject to provision of the Lease to retain  possession  of the same without any
representations, warranties, or covenants on the part of the Landlord and in the
condition commonly referred to as "As Is".

                  4. Except as  particularly  modified by the terms hereof,  the
Initial  Lease  Agreement/Lease   Extension   Agreement/Second  Lease  Extension
Agreement/Third Lease Extension Agreement/Fourth Lease Extension Agreement/Fifth
Lease Extension Agreement shall remain in full force and effect during the term


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of the  Lease as  contained  herein,  which  terms  and  conditions  are  hereby
reaffirmed by the parties hereto.

                  5. By execution of these present,  each party acknowledges the
full and  faithful  performance  by the  other  party of the  obligations  to be
performed by the other party under the Lease to the date hereof.

                  6. This Sixth Lease Extension Agreement shall bind and benefit
the parties  hereto,  their legal  representatives,  executors,  administrators,
successors and assigns.

                  IN WITNESS  WHEREOF,  the parties  have hereto  executed  this
Agreement the date and year first above written.

WITNESS:                                ICE ASSOCIATES;
                                        as Landlord

 /s/ John J. Horgan                     By:    /s/ Salvatore V. Frassetto
                                            Salvatore V. Frassetto, Partner

WITNESS:                                DALTEX MEDICAL SCIENCES, INC.;
                                        as Tenant
  /s/ Sylvia Leichter                   By:    /s/ Diane E. Fritz
                                            Diane E. Fritz, Vice President and
                                            Assistant Corporate Secretary

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