AMENDMENT NO. 9
                            TO THE WARRANT AGREEMENT




                  AGREEMENT  dated as of April 22,  1997 by and  between  Daltex
Medical  Sciences,   Inc.,  a  Delaware   corporation  (the  "Corporation")  and
Continental Stock Transfer and Trust Company, a limited purpose trust company.

                                    RECITALS

                  WHEREAS,  the Corporation has extended the expiration dates of
its Class A  Warrants  and Class B  Warrants  pursuant  to  Section  2.05 of the
Warrant Agreement dated as of October 2, 1984 (the "Warrant Agreement");

                  WHEREAS,  the parties desire to amend the Warrant Agreement as
set forth herein.

                  NOW,  THEREFORE,  in  consideration  of the mutual  agreements
contained herein, the parties hereto agree as follows:

                  SECTION 2.02 Warrant Rights and Term. Exercise of each Warrant
                  shall   entitle   the  person  in  whose  name  such   Warrant
                  Certificate  shall then be registered on the books  maintained
                  by the Warrant  Agent (the "Warrant  Holder"),  subject to the
                  provisions  of this  Agreement  and the  Warrant  Certificate,
                  including  provisions  relating to adjustments,  to (i) in the
                  case of the  exercise of a Class A Warrant at the then Class A
                  Exercise  Price,  one fully paid and  non-assessable  share of
                  Common  Stock and one Class B Warrant at any time on and after
                  the date hereof until the  expiration  of such Class A Warrant
                  at 5:00 p.m., New York City time on December 31, 1997, or such
                  later date as may be  established  pursuant to Section 2.05 or
                  such  earlier date as may be  established  pursuant to Section
                  2.06(e) (the "Class A  Expiration  Date") and (ii) in the case
                  of the  exercise  of a Class B  Warrant,  at the then  Class B
                  Exercise  Price,  one fully paid and  non-assessable  share of
                  Common Stock at any time on and after such Class B Warrant has
                  become  issuable  until the expiration of such Class B Warrant
                  at 5:00 p.m.,  New York City time,  on December 31,  1997,  or
                  such later date as may be established pursuant to Section 2.05
                  or such earlier date


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                  as may be established pursuant to Section
                  2.06(e) (the "Class B Expiration Date").

                  IN WITNESS  WHEREOF,  the  parties  hereto  have  caused  this
Agreement to be executed by their respective officers thereunto duly authorized,
as of the date first above written.

                                   DALTEX MEDICAL SCIENCES, INC.


                                   By:     /s/ Diane E. Fritz
                                           Diane E. Fritz
                                           Vice President and Assistant
                                           Corporate Secretary


                                   CONTINENTAL STOCK TRANSFER AND TRUST
                                   COMPANY, as Warrant Agent


                                   By:    /s/ William F. Seegraber
                                         Name:  William F. Seegraber
                                         Title: Vice President




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