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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                   FORM 10-KSB

                Annual Report Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934

For the Fiscal Year Ended                            Commission File No. 0-23047
December 31, 2002

                             SIGA Technologies, Inc.
             (Exact name of registrant as specified in its charter)

              Delaware                                          13-3864870
   (State or other jurisdiction of                        (IRS Employer Id. No.)
    incorporation or organization)

   420 Lexington Avenue, Suite 601                          New York, NY 10170
(Address of principal executive offices)                        (zip code)

       Registrant's telephone number, including area code: (212) 672-9100

           Securities registered pursuant to Section 12(b) of the Act:

                                      None
                                (Title of Class)

           Securities registered pursuant to Section 12(g) of the Act:

                         common stock, $.0001 par value
                                (Title of Class)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes |X| No |_|.

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-B is not contained herein, and will not be contained, to the
best of registrant's knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-KSB or any amendment to
this Form 10-KSB. |_|.

The aggregate market value of the voting stock held by non-affiliates of the
registrant, based upon the closing sale price of the common stock on March 20,
2003 as reported on the Nasdaq SmallCap Market was approximately $16,268,778. As
of March 20 , 2002 the registrant had outstanding 13,226,649 shares of common
stock. For the year ended December 31, 2002 SIGA had revenues of $344,450.
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                             SIGA Technologies, Inc.

                                   Form 10-KSB

                                Table of Contents


Part I                                                                  Page No.

Item 1   Business...........................................................   1

Item 2   Properties.........................................................  14

Item 3   Legal Proceedings..................................................  14

Item 4   Submission of Matters to a Vote of Security Holders................  14


Part II

Item 5   Market for Registrant's Common Equity and Related Stockholder
         Matters............................................................  15

Item 6   Management's Discussion and Analysis for Financial Condition
         and Results of Operations..........................................  18

Item 7   Financial Statements and Supplementary Data........................  29

Item 8   Changes in and Disagreements with Accountants on Accounting and
         Financial Disclosure...............................................  30


Part III

Item 9   Directors and Executive Officers of the Registrant.................  31

Item 10  Executive Compensation.............................................  33

Item 11  Security Ownership of Certain Beneficial Owners and Management
         and Related Stockholder Matters ...................................  35

Item 12  Certain Relationships and Related Transactions.....................  38


Part IV

Item 13  Exhibits, Lists and Reports on Form 8-K............................  39

Item 14  Controls and Procedures............................................  44

Item 15  Principal Accountant Fees and Services.............................  44

Signatures..................................................................  45




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                                     PART I


Item 1. Business

      Certain statements in this Annual Report on Form 10-KSB, including certain
statements contained in "Business" and "Management's Discussion and Analysis of
Financial Condition and Results of Operations," constitute "forward-looking
statements" within the meaning of Section 27A of the Securities Act of 1933, as
amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The
words or phrases "can be," "expects," "may affect," "may depend," "believes,"
"estimate," "project" and similar words and phrases are intended to identify
such forward-looking statements. Such forward-looking statements are subject to
various known and unknown risks and uncertainties and SIGA cautions you that any
forward-looking information provided by or on behalf of SIGA is not a guarantee
of future performance. SIGA's actual results could differ materially from those
anticipated by such forward-looking statements due to a number of factors, some
of which are beyond SIGA's control, including (i) the volatile and competitive
nature of the biotechnology industry, (ii) changes in domestic and foreign
economic and market conditions, and (iii) the effect of federal, state and
foreign regulation on SIGA's businesses. All such forward-looking statements are
current only as of the date on which such statements were made. SIGA does not
undertake any obligation to publicly update any forward-looking statement to
reflect events or circumstances after the date on which any such statement is
made or to reflect the occurrence of unanticipated events.

      SIGA Technologies, Inc. is referred to throughout this report as "SIGA,"
"the Company," "we" or "us."

Introduction

      SIGA is a development stage biotechnology company incorporated in Delaware
on December 9, 1996. We aim to discover, develop and commercialize vaccines,
antibiotics and novel anti-infectives for serious infectious diseases. Our lead
vaccine candidate is for the prevention of group A streptococcal pharyngitis or
"strep throat." We are developing a technology for the mucosal delivery of our
vaccines which may allow those vaccines to activate the immune system at the
mucus lined surfaces of the body -- the mouth, the nose, the lungs and the
gastrointestinal and urogenital tracts -- the sites of entry for most infectious
agents. We focus our anti-infectives program on the increasingly serious problem
of drug resistance. These programs are designed to block the ability of bacteria
to attach to human tissue, the first step in the infection process.


Technology

   Vaccine Technologies: Mucosal Immunity and Vaccine Delivery

      Using proprietary technology licensed from The Rockefeller University
("Rockefeller"), SIGA is developing certain commensal bacteria ("commensals") as
a means to deliver mucosal vaccines. Commensals are harmless bacteria that
naturally inhabit the body's surfaces with different commensals inhabiting
different surfaces, particularly the mucosal surfaces. Our vaccine candidates
use genetically engineered commensals to deliver antigens for a variety of
pathogens to the mucosal immune system. When administered, the genetically
engineered commensals colonize the mucosal surface and replicate. By activating
a local mucosal immune response, our vaccine candidates are designed to prevent
infection and disease at the earliest possible stage. By comparison, most
conventional vaccines are designed to act after infection has already occurred.

      Our commensal vaccine candidates use Gram-positive bacteria. Rockefeller
scientists have identified a protein region that is used by Gram-positive
bacteria to anchor proteins to their surfaces. We are using the proprietary
technology licensed from Rockefeller to combine antigens from a wide range of
infectious organisms, both viral and bacterial, with the surface protein anchor
region of a variety of commensal organisms. By combining a specific antigen with
a specific commensal, vaccines may be tailored to both the target pathogen and
its mucosal point of entry.



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      To target an immune response to a particular mucosal surface, a commensal
vaccine would employ a commensal organism that naturally inhabits that surface.
For example, vaccines targeting sexually transmitted diseases might employ
Lactobacillus acidophilus, a commensal colonizing the female urogenital tract.
Vaccines targeting gastrointestinal diseases could employ Lactobacillus casei, a
commensal colonizing the gastrointestinal tract. We have conducted initial
experiments using Streptococcus gordonii ("S. gordonii"), a commensal that
colonizes the oral cavity and which may be used in vaccines targeting pathogens
that enter through the upper respiratory tract, such as the influenza virus.

      By using an antigen unique to a given pathogen, the technology may
potentially be applied to any infectious agent that enters the body through a
mucosal surface. Our founding scientists have expressed and anchored a variety
of viral and bacterial antigens on the outside of S. gordonii, including the M6
protein from group A streptococcus, a group of organisms that causes a range of
diseases, including strep throat, necrotizing fasciitis, impetigo and scarlet
fever. In addition, proteins from other infectious agents, such as HIV and human
papilloma virus have also been expressed using this system. We believe this
technology will enable the expression of most antigens regardless of size or
shape. In animal studies, we have shown that the administration of a genetically
engineered S. gordonii vaccine prototype induces both a local mucosal immune
response and a systemic immune response.

     We believe that mucosal vaccines developed using our proprietary commensal
delivery technology could provide a number of advantages, including:

      o     More complete protection than conventional vaccines: Mucosal
            vaccines in general may be more effective than conventional
            parenteral vaccines, due to mucosal vaccines' ability to produce
            both a systemic and local (mucosal) immune response.

      o     Safety advantage over other live vectors: A number of bacterial
            pathogens have been genetically rendered less infectious, or
            attenuated, for use as live vaccine vectors. Commensals, by virtue
            of their substantially harmless nature, may offer a safer delivery
            vehicle without fear of genetic reversion to the infectious state
            inherent in attenuated pathogens.

      o     Non-injection administration: Oral, nasal, rectal or vaginal
            administration of the vaccine eliminates the need for painful
            injections with their potential adverse reactions.

      o     Potential for combined vaccine delivery: The Children's Vaccine
            Initiative, a world wide effort to improve vaccination of children
            sponsored by the World Health Organization (WHO), has called for the
            development of combined vaccines, specifically to reduce the number
            of needle sticks per child, by combining several vaccines into one
            injection, thereby increasing compliance and decreasing disease. We
            believe our commensal delivery technology can be an effective method
            of delivery of multi-component vaccines within a single commensal
            organism that address multiple diseases or diseases caused by
            multiple strains of an infectious agent.

      o     Eliminating need for refrigeration: One of the problems confronting
            the effective delivery of parenteral vaccines is the need for
            refrigeration at all stages prior to injection. The stability of the
            commensal organisms in a freeze-dried state would, for the most
            part, eliminate the need for special climate conditions, a critical
            consideration, especially for the delivery of vaccines in developing
            countries.

      o     Low cost production: By using a live bacterial vector, extensive
            downstream processing is eliminated, leading to considerable cost
            savings in the production of the vaccine. The potential for
            eliminating the need for refrigeration would add considerably to
            these savings by reducing the costs inherent in refrigeration for
            vaccine delivery.


   Anti-Infectives Technology: Prevention of Attachment and Infectivity

      The bacterial infectious process generally includes three steps:
colonization, invasion and disease. The adherence of bacteria to a host's
surface is crucial to establishing colonization. Bacteria adhere through a
number of mechanisms, but generally by using highly specialized surface
structures which, in turn, bind to specific structures or molecules on the
host's cells or, as discussed below, to inanimate objects residing in the host.
Once adhered,


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many bacteria will invade the host's cells and either establish residence or
continue invasion into deeper tissues. During any of these stages, the invading
bacteria can cause the outward manifestations of disease, in some cases through
the production and release of toxin molecules. The severity of disease, while
dependent on a large combination of factors, is often the result of the ability
of the bacteria to persist in the host. These bacteria accomplish this
persistence by using surface molecules which can alter the host's nonspecific
mechanisms or its highly specific immune responses to clear or destroy the
organisms.

      Unlike conventional antibiotics, as discussed above, our anti-infectives
approaches aim to block the ability of pathogenic bacteria to attach to and
colonize human tissue, thereby preventing infection at its earliest stage. Our
scientific strategy is to inhibit the expression of bacterial surface proteins
required for bacterial infectivity. We believe that this approach has promise in
the areas of hospital-acquired drug-resistant infections and a broad range of
other diseases caused by bacteria.

      Many special surface proteins used by bacteria to infect the host are
anchored in the bacterial cell wall. Scientists at Rockefeller University have
identified an amino acid sequence and related enzyme, a selective protease, that
are essential for anchoring proteins to the surface of most Gram-positive
bacteria. Published information indicates that this amino acid sequence is
shared by more than 50 different surface proteins found on a variety of
Gram-positive bacteria. This commonality suggests that this protease represents
a promising target for the development of a new class of antibiotic products for
the treatment of a wide range of infectious diseases. Experiments by our
founding scientists have shown that without this sequence, proteins cannot
become anchored to the bacterial surface and thus the bacteria are no longer
capable of attachment, colonization or infection. Such "disarmed" bacteria
should be readily cleared by the body's immune system. Our drug discovery
strategy is to use a combination of structure-based drug design and high
throughput screening procedures to identify compounds that inhibit the protease,
thereby blocking the anchoring process. If successful, this strategy should
provide relief from many Gram-positive bacterial infections, but may prove
particularly important in combating diseases caused by the emerging antibiotic
resistance of the Gram-positive organisms S. aureus, Streptococcus pneumoniae,
and the enterococci.

      In contrast to the above program, which focuses on Gram-positive bacteria,
our pilicide program, based upon initial research performed at Washington
University, focuses on a number of new and novel targets all of which impact on
the ability of Gram-negative bacteria to assemble adhesive pili on their
surfaces. Pili are proteins on the surfaces of Gram-negative bacteria -- such as
E. coli, salmonella, and shigella -- that are required for the attachment of the
bacteria to human tissue, the first step in the infection process. This research
program is based upon the well-characterized interaction between a periplasmic
protein -- a chaperone -- and the protein subunits required to form pili. In
addition to describing the process by which chaperones and pili subunits
interact, we have developed the assay systems necessary to screen for potential
therapeutic compounds, and have provided an initial basis for selecting novel
antibiotics that work by interfering with the pili adhesion mechanism.


   Surface Protein Expression System ("SPEX")

      The ability to overproduce many bacterial and human proteins has been made
possible through the use of recombinant DNA technology. The introduction of DNA
molecules into E. coli has been the method of choice to express a variety of
gene products, because of this bacteria's rapid reproduction and well-understood
genetics. Yet despite the development of many efficient E. coli-based gene
expression systems, the most important concern continues to be associated with
subsequent purification of the product. Recombinant proteins produced in this
manner do not readily cross E. coli's outer membrane, and as a result, proteins
must be purified from the bacterial cytoplasm or periplasmic space. Purification
of proteins from these cellular compartments can be very difficult. Frequently
encountered problems include low product yields, contamination with potentially
toxic cellular material (i.e., endotoxin) and the formation of large amounts of
partially folded polypeptide chains in non-active aggregates termed inclusion
bodies.

      To overcome these problems, we have taken advantage of our knowledge of
Gram-positive bacterial protein expression and anchoring pathways. This pathway
has evolved to handle the transport of surface proteins that vary widely in
size, structure and function. Modifying the approach used to create commensal
mucosal vaccines, we have


                                     - 3 -
<PAGE>

developed methods which, instead of anchoring the foreign protein to the surface
of the recombinant Gram-positive bacteria, result in it being secreted into the
surrounding medium in a manner which is readily amenable to simple batch
purification. We believe the advantages of this approach include the ease and
lower cost of Gram-positive bacterial growth, the likelihood that secreted
recombinant proteins will be folded properly, and the ability to purify
recombinant proteins from the culture medium without having to disrupt the
bacterial cells and liberating cellular contaminants. Gram-positive bacteria may
be grown simply in scales from those required for laboratory research up to
commercial mass production.

Product Candidates and Market Potential

   Mucosal Vaccines

      Development of our mucosal vaccine candidates involves: (i) identifying a
suitable immunizing antigen from a pathogen; (ii) selecting a commensal that
naturally colonizes the mucosal point of entry for that pathogen; and (iii)
genetically engineering the commensal to express the antigen on its surface for
subsequent delivery to the target population.

      Strep Throat Vaccine Candidate. Until the age of 15, many children suffer
recurrent strep throat infections. Up to three percent of ineffectively treated
strep throat cases progress to rheumatic fever, a debilitating heart disease,
which worsens with each succeeding streptococcal infection. Since the advent of
penicillin therapy, rheumatic fever in the United States has experienced a
dramatic decline. However, in the last decade, rheumatic fever has experienced a
resurgence in the United States. Part of the reason for this is the latent
presence of this organism in children who do not display symptoms of a sore
throat, and, therefore, remain untreated and at risk for development of
rheumatic fever. Based on data from the Centers for Disease Control and
Prevention, there are five to 10 million cases of pharyngitis due to group A
streptococcus in the United States each year. There are over 32 million children
in the principal age group targeted by us for vaccination. Worldwide, it is
estimated that one percent of all school age children in the developing world
have rheumatic heart disease. Additionally, despite the relative ease of
treating strep throat with antibiotics, the specter of antibiotic resistance is
always present. In fact, resistance to erythromycin, the second line antibiotic
in patients allergic to penicillin, has appeared in a number of cases.

      We believe that the reason no vaccine for strep throat has been developed
is because of problems associated with identifying an antigen that is common to
the more than 120 different serotypes of group A streptococcus, the bacterium
that causes the disease. We have licensed from Rockefeller a proprietary antigen
which is common to most types of group A streptococcus, including types that
have been associated with rheumatic fever. When this antigen was orally
administered to animals, it was shown to provide protection against multiple
types of group A streptococcal infection. Using this antigen, we are seeking to
develop a mucosal vaccine for strep throat.

      Our strep throat vaccine candidate expresses the strep throat antigen on
the surface of the commensal S. gordonii, which lives on the surface of the
teeth and gums. Pre-clinical research in mice and rabbits has established the
ability of this vaccine candidate to colonize and induce both a local and
systemic immune response. We are collaborating with the National Institutes of
Health ("NIH") and the University of Maryland Center for Vaccine Development on
the clinical development of this vaccine candidate. In cooperation with the NIH
we filed an Investigational New Drug Application ("IND") with the United States
Food and Drug Administration (the "FDA") in December 1997. The first stage of
these clinical trials, using the commensal delivery system without the strep
throat antigen, were completed at the University of Maryland in 2000. The study
showed the commensal delivery system to be well-tolerated and that it
spontaneously eradicated or was easily eradicated by conventional antibiotics. A
second clinical trial of the commensal delivery system without the strep throat
antigen was initiated in 2000 at the University of Maryland. The study was
completed in January 2002 and the results corroborated the results of the
earlier study regarding tolerance and spontaneous eradication.

      In the U.S. there are about 19 million children aged 2 to 6 years who
could be candidates to receive such a vaccine at the time of its introduction
and then around 4 million babies born each year to be protected. Assuming a
charge of $25 per dose and three doses needed for protection, there could be a
potential market for a strep throat


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<PAGE>

vaccine of $1.4 billion to immunize the entire U.S. population of 2 to 6 year
olds and, thereafter, $300 million per year to maintain immunization in new
births.

      STD Vaccine Candidates. One of the great challenges in vaccine research
remains the development of effective vaccines to prevent sexually transmitted
diseases ("STDs"). Two principal pathogens that are transmitted via this route
are chlamydia, the most common bacterial STD, and Neisseria, the causative agent
of gonorrhea. To date, a great deal of effort has been expended, without
appreciable success, to develop effective injectable prophylactic vaccines
versus these pathogens. Given that both of these pathogens enter the host
through the mucosa, we believe that induction of a vigorous mucosal response to
certain bacterial antigens may protect against acquisition of the initial
infection. To test this hypothesis, we have expressed newly discovered antigens
from these pathogens in our proprietary mucosal vaccine delivery system. These
live genetically engineered vaccines will be delivered to animals and tested for
local and systemic immune response induction, and whether these responses can
block subsequent bacterial infections. We have licensed technology from Oregon
State University and Washington University in support of our chlamydia and
Neisseria programs, respectively. In February 2000 we entered into an option
agreement with the Ross Products Division of Abbott Laboratories ("Ross"), which
will provide funding for further development of an STD vaccine product. The
research program was completed in late 2001 and a report has been sent to Ross.
Following review of the data, the agreement was extended to allow for an
additional set of experiments to be conducted.

      Chlamydia is the leading sexually transmitted disease in the U.S., with an
estimated 4 million cases occurring annually. Up to $2.4 billion is spent
annually on the treatment of infections from this pathogen, with the greatest
percentage of this cost directed toward the therapy of chlamydial infection in
women. Vaginal infection with C. trachomatis can progress to pelvic inflammatory
disease, resulting in infertility, or may result in ectopic pregnancies. In
addition, new evidence has linked C. trachomatis infection with an increased
incidence of cervical cancer.

      The target population for STD vaccines is likely to be 12 - 18 years of
age. There are currently 27.5 million such individuals in the U.S., with around
4 million entering this age group annually. Once again, assuming $25 per dose
and three doses to complete immunization, there could be a potential market for
a C. trachomatis vaccine of $2 billion to immunize the entire U.S. population of
12 to 18 year olds and, thereafter, $300 million per year to maintain
immunization in those entering this age group.

   Mucosal Vaccine Delivery System

      We are developing our proprietary mucosal vaccine delivery system, which
is a component of our vaccine program, for license to other vaccine developers.
Our commensal vaccine candidates utilize Gram-positive bacteria to deliver
antigens. We are using proprietary technology to anchor antigens from a wide
range of infectious organisms, both viral and bacterial, to the surface protein
anchor region of a variety of commensal organisms. By combining a specific
antigen with a specific commensal, we believe that vaccines can be tailored to
both the target pathogen and its mucosal point of entry.

      We have developed several genetic methods for recombining foreign
sequences into the genome of Gram-positive bacteria at a number of non-essential
sites. Various parameters have been tested and optimized to improve the level of
foreign protein expression and its immunogenicity. In pre-clinical studies,
genetically engineered commensals have been implanted into the oral cavities of
several animal species with no observed deleterious effects. The introduced
vaccine strains have taken up residence for prolonged periods of time and induce
both a local mucosal (IgA) as well as a systemic immune response (IgG and
T-cell).

      We have completed two early stage clinical evaluations of our mucosal
vaccine delivery system based on the commensal bacterium, S. gordonii. These
clinical studies were designed to test the safety of the formulation, to monitor
the extent and duration of colonization of the nasal and oral cavities and to
determine if the delivery system could be eradicated at the end of the study
with a regimen of conventional antibiotics. A total of 47 volunteers between the
ages of 18 and 40 completed the first study, performed in the United Kingdom, in
which S. gordonii was delivered to the nasal passage and oral cavity. A total of
60 volunteers completed a second study which was


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conducted at the University of Maryland as part of our strep throat vaccine
program as described above. The results of the studies indicated the delivery
system was well-tolerated and that the delivery system spontaneously eradicated
or was easily eradicated by conventional antibiotics. The ongoing clinical
studies at the University of Maryland are also designed to evaluate S. gordonii
as a commensal bacterial delivery system for our vaccine targeting strep throat.
Experiments are currently underway to optimize and test the vaccine formulation
prior to initiating Phase I human trials with the recombinant commensal vector
based vaccine.

   Anti-Infectives

      Our anti-infectives program is targeted principally toward drug-resistant
bacteria and hospital-acquired infections. According to estimates from the
Centers for Disease Control, approximately two million hospital-acquired
infections occur each year in the United States.

      Our anti-infectives approaches aim to block the ability of bacteria to
attach to and colonize human tissue, thereby blocking infection at the first
stage in the infection process. By comparison, antibiotics available today act
by interfering with either the structure or the metabolism of a bacterial cell,
affecting its ability to survive and to reproduce. No currently available
antibiotics target the attachment of a bacterium to its target tissue. We
believe that, by preventing attachment, the bacteria should be readily cleared
by the body's immune system.

      Gram-Positive Antibiotic Technology. Our lead anti-infectives program is
based on a novel target for antibiotic therapy. Our founding scientists have
identified an enzyme, a selective protease, used by most Gram-positive bacteria
to anchor certain proteins to the bacterial cell wall. These surface proteins
are the means by which certain bacteria recognize, adhere to and colonize
specific tissue. Our strategy is to develop protease inhibitors as novel
antibiotics. We believe protease inhibitors will have wide applicability to
Gram-positive bacteria in general, including antibiotic resistant staphylococcus
and a broad range of serious infectious diseases including meningitis and
respiratory tract infections. In 1997, we entered into a collaborative research
and license agreement with Wyeth to identify and develop protease inhibitors as
novel antibiotics. In the first quarter of 2001, we received a milestone payment
from Wyeth for delivery of the first quantities of protease for screening, and
high-throughput screening for protease inhibitors was initiated. In connection
with our effort on this program we have entered into a license agreement with
the University of California at Los Angeles for certain technology that may be
incorporated into our development of products for Wyeth. High throughput
screening of compound libraries has been completed and lead compounds are
currently being evaluated in the laboratory.

      Gram-Negative Antibiotic Technology. In 1998 we entered into a set of
technology transfer and related agreements with MedImmune, Inc., Astra AB and
The Washington University, St. Louis ("Washington University"), pursuant to
which we acquired rights to certain Gram-negative antibiotic targets, products,
screens and services developed at Washington University. In February 2000, we
ended our collaborative research and development relationship with Washington
University on this technology. (See "Collaborative Research and Licenses"). We
maintain a non-exclusive license to technology acquired through these related
agreements. We are using this technology in the development of antibiotics
against Gram-negative pathogens. These bacteria use structures called pili to
adhere to target tissue, and we plan to exploit the assembly and export of these
essential infective structures as novel anti-infective targets. We continue to
work on enhancing the intellectual property that we jointly share with
Washington University.

      Broad-Spectrum Antibiotic Technology. An initial host response to pathogen
invasion is the release of oxygen radicals, such as superoxide anions and
hydrogen peroxide. The DegP protease is a first-line defense against these toxic
compounds, which are lethal to invading pathogens, and is a demonstrated
virulence factor for several important Gram-negative pathogens: Salmonella
typhimurium, Salmonella typhi, Brucella melitensis and Yersinia enterocolitica.
In all of these pathogens it was demonstrated that organisms lacking a
functional DegP protease were compromised for virulence and showed an increased
sensitivity to oxidative stress. It was also recently demonstrated that in
Pseudomonas aeruginosa conversion to mucoidy, the so-called CF phenotype
involves two DegP homologues.

      Our scientists recently demonstrated that the DegP protease is conserved
in most important Gram-positive pathogens, including S. pyogenes, S. pneumoniae,
S. mutans and S. aureus. Moreover, our investigators have shown


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a conservation of function of this important protease in Gram-positive pathogens
and believe that DegP represents a true broad-spectrum anti-infective
development target. Our research has uncovered a virulence-associated target of
the DegP protease that will be used to design an assay for high-throughput
screening for the identification of lead inhibitors of this potentially
important anti-infective target.

      There are currently more than 100 million prescriptions written for
antibiotics annually in the U.S. and we estimate the worldwide market for
antibiotics to be more than $26 billion. Although our products are too early in
development to make accurate assessments of how well they might compete, if
successfully developed and marketed against other products currently existing or
in development at this time, the successful capture of even a relatively small
global market share could lead to a large dollar volume of sales.

      Biological Defense Program. The U.S. government's budget for the fiscal
year beginning October 1, 2002 proposed a $1.5 billion increase in federal
spending on bioterrorism related research and infrastructure which will bring
total spending in this area to more than $1.7 billion. One of the major concerns
is smallpox -- although declared extinct in 1980 by the World Health
Organization, there is a threat that a rogue nation or a terrorist group may
have an illegal inventory of the virus that causes smallpox. The only legal
inventories of the virus are held under extremely tight security at the Centers
For Disease Control in Atlanta, Georgia and at a laboratory in Russia. As a
result of this threat, the U.S. government has announced its intent to make
significant expenditures on finding a way to counteract the virus if turned
loose by terrorists or on a battlefield.

      We believe that two recent events have made this area a particularly
attractive business opportunity. First, the federal government has committed
approximately $9 billion of new money to support research on biowarfare defense
in the upcoming year. Second, the FDA has amended its regulations, effective
June 30, 2002, so that certain new drug and biological products used to reduce
or prevent the toxicity of chemical, biological, radiological, or nuclear
substances may be approved for use in humans based on evidence of effectiveness
derived only from appropriate animal studies and any additional supporting data.
We believe that this change could make it possible for us to have potential
products in animal models within six months and approved for sale within two
years if the program is successful. Our Chief Scientific Officer, Dennis Hruby
has over 20 years experience working on smallpox-related research and has been
leading a SIGA/Oregon State University consortium working on an antiviral drug
development project for the past two years.

      SIGA Biological Warfare Defense Product Portfolio

         Bacterial Commensal Vectors: Our scientists have developed methods that
allow essentially any gene sequence to be expressed in GRAS gram-positive
bacteria, with the foreign protein being displayed on the surface of the live
recombinant organisms. Since these organisms are inexpensive to grow and are
very stable, this technology affords the possibility of rapidly producing live
recombinant vaccines against any variety of biological agent that might be
encountered such as Bacillus anthracis (anthrax) or smallpox.

         Surface Protein Expression (SPEX) System: Our scientists have harnessed
the protein expression pathways of gram-positive bacteria and turned them into
protein productions factories. Using our proprietary SPEX system, we can produce
foreign proteins at high levels in the laboratory for use in subunit vaccine
formulations. Furthermore, we can envision engineering these bacteria to
colonize the mucosal surfaces of soldiers and/or civilians and secrete
anti-toxins that protect against aerosolized botulism toxin.

         Antibiotics: To combat the problems associated with emerging antibiotic
resistance, SIGA scientists are developing drugs designed to hit a new target -
the bacterial adhesion organelles. Specifically, by using novel enzymes required
for the transport and/or assembly of the proteins and structures that bacteria
require for adhesion or colonization, we are developing new classes of broad
spectrum antibiotics. This may prove invaluable in providing prompt treatment to
individuals encountering an unknown bacterial pathogen in the air or food
supply.

         Anti-Smallpox Drugs: While deliberate introduction of any pathogenic
agent would be devastating, the one that holds, we believe, the greatest
potential for harming the general U.S. population is smallpox. At present


                                     - 7 -
<PAGE>

there is no effective drug with which to treat or prevent smallpox infections.
To address this serious risk, our scientists have identified two key smallpox
proteinases and are using their expertise in the design of proteinase inhibitors
to attempt to develop an effective antiviral drug that could treat a smallpox
infection.

         The market potential for our biological warfare defense products has
not been quantified as yet beyond the potential to obtain a share of the
approximately $9 billion the federal government is committing to support
research in the coming year. The government's purchase of approximately $800
million worth of smallpox vaccines to have an inventory on hand if needed is
evidence of such market potential.

   Veterinary Vaccines

      One application of our technology is the development of live vaccines that
are delivered to a specific mucosal niche where they can colonize and thereby
present antigen to the immune system and produce local immunity at the site
where the corresponding pathogen may attempt to enter. Since the proprietary
expression pathway that we use is conserved in essentially all Gram-positive
bacteria, this should allow the same strategy to be employed in the development
of veterinary vaccines. A commensal bacterium can be isolated from the mucosa of
the target species, engineered to express a desired antigen and then
reintroduced to the species in order to produce immunity against subsequent
infection by the corresponding pathogen. Examples of potential targets for this
technology in the area of animal health include prevention of salmonid
aquaculture disease problems or canine papilloma virus infections.

      Veterinary Program. We believe our vaccine and anti-infectives
technologies also provide opportunities to develop biopharmaceutical products
for the veterinary health care market. Based on sales of the major companies in
the veterinary market, we estimate the world wide veterinary market to have been
approximately $4 billion in 2001. In the U.S. alone, there are 120 million cats
and dogs, 2 million horses, 100 million cattle, 56 million hogs and 8 million
sheep and goats. We are in discussions with a number of potential strategic
partners to undertake collaborative development agreements in this field. To
date, we have not concluded any agreements with these potential strategic
partners. In April 2002 we executed a proof-of-concept research agreement with
one of the major vaccine providers to test our commensal vector technology. This
project has been completed and the partner company is currently evaluating the
data.

   Surface Protein Expression System

      Our proprietary SPEX system uses the protein export and anchoring pathway
of Gram-positive bacteria as a means to facilitate the production and
purification of biopharmaceutical proteins. We have developed vectors which
allow foreign genes to be inserted into the chromosome of Gram-positive bacteria
in a manner such that the encoded protein is synthesized, transported to the
cell surface and secreted into the medium. This system has been used to produce
milligram quantities of soluble antigenically authentic protein that can be
easily purified from the culture medium by affinity chromatography. We have
recently used the SPEX system to obtain large quantities of pure M protein
subunit antigen for preclinical studies. We believe this technology can be
extended to a variety of different antigens and enzymes.

      We have commenced yield optimization and process validation of this
system. This program is designed to transfer the method from a laboratory scale
environment to a commercial production facility. Our business strategy is to
license this technology on a non-exclusive basis for a broad range of
applications.

Collaborative Research and Licenses

      We have entered into the following license agreements and collaborative
research arrangements:

      Rockefeller University. In accordance with an exclusive worldwide license
agreement with Rockefeller, we have obtained the right and license to make, use
and sell mucosal vaccines based on gram-positive organisms and products for the
therapy, prevention and diagnosis of diseases caused by streptococcus,
staphylococcus and other organisms. The license covers two issued U.S. patents
and one issued European patent, as well as 11 pending U.S.


                                     - 8 -
<PAGE>

patent applications and corresponding foreign patent applications. The issued
United States patents expire in 2005 and 2014, respectively. The agreement
generally requires us to pay royalties on sales of products developed from the
licensed technologies and fees on revenues from sublicensees, where applicable,
and we are responsible for certain milestone payments and for the costs of
filing and prosecuting patent applications. The primary potential products from
this collaboration are the strep vaccine and the broad spectrum antibiotic.
Under the agreement, we paid the university approximately $850,000 to support
research at Rockefeller. The agreement to fund research has ended and no
payments have been made to the university since the year ended December 31,
1999. Under the agreement we are obligated to pay Rockefeller a royalty on net
sales by SIGA at rates between 2.5% and 5% depending on product and amount of
sales. On sales by any sub-licensee, we will pay Rockefeller a royalty of 15% of
anything we receive. The term of the agreement is for the duration of the
patents licensed. At the end of that period, we have the right to continue to
practice the then existing technical information as a fully paid, perpetual
license.

      Oregon State University. Oregon State University ("OSU") is also a party
to our license agreement with Rockefeller whereby we have obtained the right and
license to make, use and sell products for the therapy, prevention and diagnosis
of diseases caused by streptococcus. Pursuant to a separate research support
agreement with OSU, we provided funding for sponsored research through December
31, 1999, with exclusive license rights to all inventions and discoveries
resulting from this research. At this time, no additional funding is
contemplated under this agreement, however we retain the exclusive licensing
rights to the inventions and discoveries that may arise from this collaboration.

      During 1999, we acquired an option to enter into a license with OSU in
which we will acquire the rights to certain technology pertaining to the
potential development of a chlamydia vaccine. In February 2000, we exercised our
option and pursuant to an exclusive license agreement dated March 2000, we have
made payments to OSU of approximately $25,000 as part of our obligation under
the option.

      In September 2000, we entered into a subcontract with OSU. The contract is
for a project which is targeted towards developing novel antiviral drugs capable
of preventing disease and pathology for smallpox in the event this pathogen were
to be used as an agent of bioterrorism. The project is being funded by a grant
from the NIH. The basic virology aspects of the project will be conducted at OSU
and the drug development will be performed by us under the subcontract. The
budget for the subcontract work will be negotiated on a year by year basis with
OSU depending on progress of the program and funding available. In the year
ended December 31, 2001 we recognized revenue of $15,000. On October 5, 2001 the
agreement was extended through August 31, 2002. For the period ended December
31, 2002 we recognized $75,000 in revenue. The agreement was extended again
through August 31, 2003. The sub-contract is on a year to year renewal. Through
December 31, 2002 we have received a total of $90,000 under the agreement.

      Wyeth. We have entered into a collaborative research and license agreement
with Wyeth in connection with the discovery and development of anti-infectives
for the treatment of gram-positive bacterial infections. Pursuant to the
agreement, Wyeth provided funding for a joint research and development program,
subject to certain milestones, through September 30, 1999 and is responsible for
additional milestone payments. In May 2001, we entered into an amendment to the
July 1, 1997 agreement. The amendment extended the term of the original
agreement to September 30, 2001. The extension provided for Wyeth to continue to
pay us at a rate of $450,000 per year through the term of the amended agreement.
During the term of the agreement as amended, we received $787,500 from Wyeth to
support work performed by SIGA under the agreement and $237,500 for achieving a
research milestone. For the year ended December 31, 2001 we recognized revenue
of $1,025,000. The agreement to fund additional research was not extended beyond
September 30, 2001.

      Wyeth is obligated to make milestone payments to us as any product
developed progresses through the FDA approval process. For product developed we
could receive up to approximately $13 million in milestone payments for approval
of the product in the U.S. and Japan. We would also receive royalty payments of
2% on the first $300,000 of cumulative licensed product sales, 4% on annual
sales up to $100 million, 6% on annual sales between $100 million and $250
million and 8% on annual sales above $250 million. The license will expire on
the earlier of 10 years or the last to expire issued patent. Wyeth has the right
to terminate the agreement early, on ninety days written notice. If terminated
early, all rights granted to Wyeth revert to SIGA except with respect to any


                                     - 9 -
<PAGE>

compound identified by Wyeth as of the date of termination and subject to the
milestone and royalty obligations of the agreement.

      National Institutes of Health. We have entered into a clinical trials
agreement with the NIH pursuant to which the NIH, with our cooperation, will
conduct clinical trials of our strep throat vaccine candidate. The agreement
will fund trials through Phase II of the FDA approval process. To date, two
Phase I clinical trials have been conducted for the strep vaccine delivery
system. We are working to optimize and test the vaccine formulation prior to
initiating Phase I clinical trials with the recombinant commensal vector based
vaccine. The agreement may be terminated unilaterally by the parties upon sixty
days prior notice. If terminated we will receive copies of all data, reports and
other information related to the trials and any unused vaccine.

       In May, August and September 2000, we were awarded three Phase I Small
Business Innovation Research ("SBIR") grants from the NIH in the amounts of
$26,000, $96,000 and $125,000 respectively. The grants were for the periods May
3, 2000 to August 31, 2000, August 1, 2000 to January 31, 2001, and September
15, 2000 to March 14, 2001 respectively, and supported our antibiotic and
vaccine development programs. In June 2002 we received a Phase II SBIR grant for
approximately $865,000. The grant was for the two year period beginning June, 1,
2002 and ending May 31, 2004. For the years ending December 31, 2002, 2001 and
2000, we have recognized revenue from grants of $270,000, $64,500 and $182,643,
respectively.

       As part of our operational strategy we routinely submit grants to the
NIH. There is no assurance that we will receive additional grants

      Washington University. In February 1998, we entered into a research
collaboration and worldwide license agreement with Washington University
pursuant to which we obtained the right and license to make, use and sell
antibiotic products based on gram-negative technology for all human and
veterinary diagnostic and therapeutic uses. The license covered five pending
United States patent applications and corresponding foreign patent applications.
The agreement generally required us to pay royalties on sales of products
developed from the licensed technologies and fees on revenues from sublicensees,
where applicable, and we were responsible for certain milestone payments and for
the costs of filing and prosecuting patent applications. Pursuant to the
agreement, we agreed to provide funding to Washington University for sponsored
research through February 6, 2001, with exclusive license rights to all
inventions and discoveries resulting from this research. During 1999, a dispute
arose between the parties regarding their respective performance under the
agreement. In February 2000, the parties reached a settlement agreement and
mutual release of their obligations under the research collaboration agreement.
Under the terms of the settlement, we are released from any further payments to
Washington University and have disclaimed any rights to the patents licensed
under the original agreement. As part of the settlement agreement, we entered
into a non-exclusive license to certain patents covered in the original
agreement. SIGA and Washington University will share equally the responsibility
for the administration and the expenses for the prosecution of patent
applications and /or patents in the agreement. The collaboration is for the
gram-negative product opportunity. We will receive licensing revenue from
Washington University that derive from the commercialization of products covered
by patent rights of the agreement. The royalty will be 20% of the first $400,000
received and 10% of the next $1,000,000 received with a total payment of
licensing revenues to us not to exceed $500,000.

      Abbott Laboratories. In March 2000, we entered into an agreement with the
Ross Products Division of Abbott Laboratories ("Ross"). The agreement grants
Ross an exclusive option to negotiate an exclusive license to certain SIGA
technology and patents in addition to certain research development services. In
exchange for research services and the option, Ross was obligated to pay us
$120,000 in three installments of $40,000. The first payment of $40,000 was
received in March 2000 and was recognized ratably, over the term of the
arrangement. The remaining installments are contingent upon meeting certain
milestones under the agreement and will be recognized as revenue upon completion
and acceptance of such milestones. The first milestone was met, and we received
an additional payment of $40,000 in the quarter ended September 30, 2000. During
the years ended December 31, 2001 and 2000, we recognized revenue in the amount
of $45,000 and $80,000, respectively. The development agreement was for the
sexually transmitted disease product opportunity. Work under the agreement has
been completed and no revenue was recognized in 2002. Ross is currently
evaluating whether it will go forward with a


                                     - 10 -
<PAGE>

license. If Ross does not exercise the option to negotiate a license with us,
all rights to the technology and possible products revert to SIGA.

      Regents of the University of California. In December 2000, we entered into
an exclusive license agreement and a sponsored research agreement with the
Regents of the University of California ("Regents"). Under the license agreement
we obtained rights for the exclusive commercial development, use and sale of
products related to certain inventions in exchange for a non-refundable license
issuance fee of $15,000 and an annual maintenance fee of $10,000. As of December
31, 2001 we have made payments of approximately $25,000 under the license In the
event that we sub-license the license, we must pay Regents 15% of all royalty
payments made to SIGA. Under the agreement, we will also pay Regents 15% of all
royalties received from Wyeth. The agreement applies to the gram positive
product opportunity and our collaborative agreement with Wyeth. The term of the
agreement is until the expiration of the last-to-expire patent licensed under
this agreement. The agreement may be terminated by Regents if we default on any
of our obligations, the agreement with Wyeth is terminated and a substitute
agreement is not entered into or if we give notice that we do not intend to make
product from the licensed technology.

      TransTech Pharma, Inc. In October 2002, we entered into a drug discovery
collaboration agreement. Under the agreement, SIGA and TransTech will
collaborate on the discovery, optimization and development of lead compounds to
therapeutic agents. The costs of development will be shared. SIGA and TransTech
would share revenues generated from licensing and profits from any
commercialized product sales. The agreement will be in effect until terminated
by the parties or upon cessation of research or sales of all products developed
under the agreement. If the agreement is terminated, relinquished or expires for
any reason certain rights and benefits will survive the termination. Obligations
not expressly indicated to survive the agreement will terminate with the
agreement. No revenues were recognized in 2002 from this collaboration.


Intellectual Property and Proprietary Rights

      Protection of our proprietary compounds and technology is essential to our
business. Our policy is to seek, when appropriate, protection for our lead
compounds and certain other proprietary technology by filing patent applications
in the United States and other countries. We have licensed the rights to seven
issued United States patents and two issued European patents. These patents have
varying lives and they are related to the technology licensed from Rockefeller
University for the strep and gram positive products. We have three additional
patent applications in the U.S. and three applications in Europe relating to
this technology. We are joint owner with Washington University of four issued
patents in the U.S. and one in Europe. In addition, there are seven co-owned
patent applications in the U.S. and one in Europe. These patents are for the
technology used for the gram-negative product opportunities. We are also
exclusive owner of two U.S. patents and three U.S. patent applications.
Furthermore, there are three U.S. patent applications and two European
applications. These patents relate to our DegP product opportunities.


                                     - 11 -
<PAGE>

--------------------------------------------------------------------------------
                        Licensed from          Co-owned with
                          Rockefeller            Washington             Owned by
PATENTS                      Univ.                  Univ.                 SIGA
--------------------------------------------------------------------------------
U.S.                           7                     4                     2
--------------------------------------------------------------------------------
Europe                         2                     1
--------------------------------------------------------------------------------
Japan                          4
--------------------------------------------------------------------------------
Australia                      6                     1
--------------------------------------------------------------------------------
Canada                         3
--------------------------------------------------------------------------------
Mexico                         1
--------------------------------------------------------------------------------
APPLICATIONS
--------------------------------------------------------------------------------
U.S.                           3                     7                     3
--------------------------------------------------------------------------------
Europe                         3                                           2
--------------------------------------------------------------------------------
Japan                          2                     1                     2
--------------------------------------------------------------------------------
Canada                         5                     1                     2
--------------------------------------------------------------------------------
Hungary                        1
--------------------------------------------------------------------------------
China                          1
--------------------------------------------------------------------------------
Korea                          1
--------------------------------------------------------------------------------
New Zeland                                           1
--------------------------------------------------------------------------------
Australia                                                                  2
--------------------------------------------------------------------------------



      We also rely upon trade secret protection for our confidential and
proprietary information. No assurance can be given that other companies will not
independently develop substantially equivalent proprietary information and
techniques or otherwise gain access to our trade secrets or that we can
meaningfully protect our trade secrets.

Government Regulation

      Regulation by governmental authorities in the United States and other
countries will be a significant factor in the production and marketing of any
biopharmaceutical products that we may develop. The nature and the extent to
which such regulations may apply to us will vary depending on the nature of any
such products. Virtually all of our potential biopharmaceutical products will
require regulatory approval by governmental agencies prior to commercialization.
In particular, human therapeutic products are subject to rigorous pre-clinical
and clinical testing and other approval procedures by the FDA and similar health
authorities in foreign countries. Various federal statutes and regulations also
govern or influence the manufacturing, safety, labeling, storage, record keeping
and marketing of such products. The process of obtaining these approvals and the
subsequent compliance with appropriate federal and foreign statutes and
regulations requires the expenditure of substantial resources.

      In order to test clinically, produce and market products for diagnostic or
therapeutic use, a company must comply with mandatory procedures and safety
standards established by the FDA and comparable agencies in foreign countries.
Before beginning human clinical testing of a potential new drug, a company must
file an IND and receive clearance from the FDA. This application is a summary of
the pre-clinical studies that were conducted to characterize the drug, including
toxicity and safety studies, as well as an in-depth discussion of the human
clinical studies that are being proposed.



                                     - 12 -
<PAGE>

      The pre-marketing program required for approval by the FDA of a new drug
typically involves a time-consuming and costly three-phase process. In Phase I,
trials are conducted with a small number of patients to determine the early
safety profile, the pattern of drug distribution and metabolism. In Phase II,
trials are conducted with small groups of patients afflicted with a target
disease in order to determine preliminary efficacy, optimal dosages and expanded
evidence of safety. In Phase III, large scale, multi-center comparative trials
are conducted with patients afflicted with a target disease in order to provide
enough data for statistical proof of efficacy and safety required by the FDA and
others.

      The FDA closely monitors the progress of each of the three phases of
clinical testing and may, in its discretion, reevaluate, alter, suspend or
terminate the testing based on the data that have been accumulated to that point
and its assessment of the risk/benefit ratio to the patient. Estimates of the
total time required for carrying out such clinical testing vary between two and
ten years. Upon completion of such clinical testing, a company typically submits
a New Drug Application ("NDA") or Product License Application ("PLA") to the FDA
that summarizes the results and observations of the drug during the clinical
testing. Based on its review of the NDA or PLA, the FDA will decide whether to
approve the drug. This review process can be quite lengthy, and approval for the
production and marketing of a new pharmaceutical product can require a number of
years and substantial funding; there can be no assurance that any approvals will
be granted on a timely basis, if at all.

      Once the product is approved for sale, FDA regulations govern the
production process and marketing activities, and a post-marketing testing and
surveillance program may be required to monitor continuously a product's usage
and its effects. Product approvals may be withdrawn if compliance with
regulatory standards is not maintained. Other countries in which any products
developed by us may be marketed could impose a similar regulatory process.

      Commercialization of animal health products can be accomplished more
rapidly than human health products. Unlike the human market, potential vaccine
or therapeutic products can be tested directly on the target animal as soon as
the product leaves the research laboratory. The data collected in these trials
is submitted to the U.S. Department of Agriculture for review and eventual
product approval.

Competition

      The biotechnology and pharmaceutical industries are characterized by
rapidly evolving technology and intense competition. Our competitors include
most of the major pharmaceutical companies, which have financial, technical and
marketing resources significantly greater than ours. Biotechnology and other
pharmaceutical competitors include Cubist Pharmaceuticals, Inc., Corixa
Corporation, Microcide Pharmaceuticals, Inc., ID Vaccines Ltd., Actinova PLC,
and Antex Biologics, Inc. Academic institutions, governmental agencies and other
public and private research organizations are also conducting research
activities and seeking patent protection and may commercialize products on their
own or through joint venture. There can be no assurance that our competitors
will not succeed in developing products that are more effective or less costly
than any which are being developed by us or which would render our technology
and future products obsolete and noncompetitive.

Human Resources and Facilities

      As of March 20, 2003 we had 17 full time employees. None of our employees
are covered by a collective bargaining agreement and we consider our employee
relations to be good.

Availability of Reports and Other Information

      Our website is www.sigatechnologies.com. We make available on this
website, free of charge, our annual, quarterly and current reports and other
documents filed by us with the Securities and Exchange Commission as soon as
reasonably practicable after the filing date.




                                     - 13 -
<PAGE>

Item 2. Properties

      Our headquarters are located in New York City and our research and
development facilities are located in Corvallis, Oregon. In New York, we lease
approximately 1,600 square feet under a lease that expires in November 2007. In
Corvallis, we lease approximately 10,000 square feet under a lease that expires
in December 2004.

Item 3. Legal Proceedings

      SIGA is not a party, nor is its property the subject of, any pending legal
proceedings other than routine litigation incidental to its business.

Item 4. Submission of Matters to a Vote of Security Holders

      At our Annual Meeting of Stockholders held on December 10, 2002, our
stockholders re-elected to our board each member of our board of directors and
ratified our selection of independent auditors:

      The following nominees were elected to our board of directors upon the
following votes:

Nominee                          Votes For       Votes Against       Abstained
-------                          ---------       -------------       ---------
Donald G. Drapkin                7,514,929              0                7,890

Gabriel M. Cerrone               7,514,929              0                7,890

Thomas E. Constance              7,514,929              0                7,890

Mehmet C. Oz                     7,410,613              0              112,206

Eric A. Rose                     7,514,929              0                7,890

Michael Weiner                   7,410,613              0              112,206

      Our stockholders ratified the selection of PricewaterhouseCoopers LLP as
our independent auditors for the fiscal year ending December 31, 2002 by casting
7,508,629 votes in favor of this proposal, 12,150 votes against the proposal and
2,040 abstained.


                                     - 14 -
<PAGE>

                                     Part II


Item 5.  Market For Registrant's Common Equity and Related Stockholder Matters

   Price Range of Common Stock

      Our common stock has been traded on the Nasdaq SmallCap Market since
September 9, 1997 and trades under the symbol "SIGA." Prior to that time there
was no public market for our common stock. The following table sets forth, for
the periods indicated, the high and low closing sales prices for the common
stock, as reported on the Nasdaq SmallCap Market.

                                   Price Range


2001                                              High         Low
                                                 ------       ------
First Quarter                                     $4.09       $1.65
Second Quarter                                    $4.24       $1.75
Third Quarter                                     $4.05       $2.29
Fourth Quarter                                    $4.00       $2.03


2002                                              High         Low
                                                 ------       ------
First Quarter                                     $2.85       $2.10
Second Quarter                                    $2.53       $1.05
Third Quarter                                     $1.39       $0.81
Fourth Quarter                                    $1.87       $0.71


      As of March 20, 2003, the closing bid price of our common stock was $1.23
per share. There were 96 holders of record as of March 20, 2003. We believe that
the number of beneficial owners of our common stock is substantially greater
than the number of record holders, because a large portion of common stock is
held in broker "street names."

      We have paid no dividends on our common stock and we do not expect to pay
cash dividends in the foreseeable future. We are not under any contractual
restriction as to our present or future ability to pay dividends. We currently
intend to retain any future earnings to finance the growth and development of
our business.

Recent Sales of Unregistered Securities

      All of the following sales of unregistered securities were made without
registration under the Securities Act in reliance upon the exemption from
registration afforded under Section 4(6) of the Securities Act and Rule 506 of
Regulation D promulgated thereunder. Accordingly, the transfer of the securities
are subject to substantial restrictions. Securities were only purchased by
"Accredited Investors" as that term is defined under Rule 501 of Regulation D.
Proceeds from the offerings were used for general working capital purposes.

      In December 2002 and January 2003, we completed a private placement of 34
units consisting of 1.7 million shares of common stock to a group of private
investors. The gross proceeds from the offering were $1,865,000 with net
proceeds to SIGA of approximately $1,682,000.



                                     - 15 -
<PAGE>

      In October 2002, we completed a private placement of units consisting of
an aggregate of 1,037,500 shares of common stock and warrants to purchase
518,750 shares of common stock at an exercise price of $2.25 per share to a
group of private investors. The offering yielded net proceeds of approximately
$935,000.

      In October 2001, we raised gross proceeds of $2.55 million in a private
offering of common stock and warrants to purchase our common stock. We sold
850,000 shares of common stock and 425,000 warrants. These warrants are
exercisable at $3.60 and have a term of seven years. In connection with the
offering we issued 100,000 warrants to purchase shares of the our common stock
to consultants. The consultants' warrants are exercisable at a price of $3.60
and have a term of five years. The fair value of the warrants on the date of
grant was approximately $221,300.

      In August 2001, we raised gross proceeds of $1,159,500 in a private
offering of 409,636 shares of common stock and 307,226 warrants to purchase
shares of our common stock. The warrants are exercisable at $3.55 per share and
have a term of seven years.

      In May 2001, we raised gross proceeds of $850,000 in a private offering of
common stock and warrants to purchase shares of our common stock. We sold
425,000 shares of common stock and 425,000 warrants. The warrants are
exercisable at $2.94 and have a term of seven years. The investors consisted of
members of the board of directors, existing investors and new investors
representing, at that time, 43.4%, 5.9% and 50.8% of the investors in the
transaction, respectively. We recorded a charge to earnings in the amount of
$103,040 representing the intrinsic value of the restricted stock purchased by
members of the board of directors.

      In March 2000, we entered into an agreement to sell 600,000 shares of our
common stock and 450,000 warrants to acquire shares of our common stock (the
"March Financing") for gross proceeds of $3,000,000. Of the warrants issued,
210,000, 120,000 and 120,000 are exercisable at $5.00, $6.38 and $6.90,
respectively. The warrants have a term of three years and are redeemable at
$0.01 each by SIGA upon meeting certain conditions. Offering expenses of
$117,000 were paid in April 2000. At December 31, 2002, all 450,000 warrants
were outstanding.

      In connection with the March Financing, we issued a total of 379,000
warrants to purchase shares of the our common stock to Fahnestock & Co. (the
"Fahnestock Warrants") in consideration for services related to the March
financing. The warrants had an exercise price of $5.00 per share and are
exercisable at any time until March 28, 2005. In November 2000, we entered into
a one year consulting agreement with Fahnestock and Co. under which we will
receive marketing, public relations acquisitions and strategic planning service.
In exchange for such services, we canceled the Fahnestock Warrants and reissued
them to effectuate an amendment to the exercise price to $2.00 per share. In
connection with such amendment, we recorded a charge of approximately $270,000
in the year ended December 31, 2000.

      In January 2000 we completed a private placement of 6% convertible
debentures at an aggregate principal amount of $1,500,000 and 1,043,478 warrants
to purchase shares of our common stock with a purchase price of $0.05 per
warrant (the "January Financing"). We received net proceeds of $1,499,674 from
the total $1,552,174 gross proceeds raised. The debentures are convertible into
common stock at $1.4375 per share. Interest at the rate of 6% per annum was
payable on the principal of each convertible debenture in cash or shares of our
common stock, at the our discretion upon conversion or at maturity. The warrants
have a term of five years and are exercisable at $3.4059 per share.

      SIGA has the right to require the holder to exercise the January Financing
warrants within five days under the following circumstances: (i) a registration
statement is effective; and (ii) the closing bid price for the Company's common
stock, for each of any 15 consecutive trading days is at least 200% of the
exercise price of such warrants. If the holder does not exercise the warrants
after notice is given, the unexercised warrants will expire. The warrants are
exercisable for a period of five years.

      In connection with the placement of the debentures and warrants in January
2000, we recorded debt discount of approximately $1.0 million. Such amount
represents the value of the warrants calculated using the


                                     - 16 -
<PAGE>

Black-Scholes valuation model. The discount is amortized over the term of the
debentures. Additionally, during the years ended December 31, 2001 and 2000, we
recorded interest expense of $232,393 and $589,312 respectively, related to the
amortization of such debt discount. In 2001 and 2000, debentures with a
principal amount of $1,375,000 and $108,664, respectively, along with accrued
interest, were converted into 1,011,593 and 108,884 shares of the Company's
preferred and common stock, respectively.

      In connection with the January financing, we issued warrants to purchase a
total of 275,000 shares of common stock to the placement agent and the
investors' counsel (or their respective designees). These warrants have a term
of five years and are exercisable at $1.45 per share. In connection with the
issuance of such warrants, the Company recorded a deferred charge of $280,653,
which was amortized over the term of the debentures.

      Holders of the Series A Convertible Preferred Stock are entitled to (i)
cumulative dividends at the annual rate of 6% payable when and if declared by
our board of directors; (ii) in the event of liquidation of SIGA, each holder is
entitled to receive $1.4375 per share (subject to certain adjustment) plus all
accrued but unpaid dividends; (iii) convert each share of Series A to a number
of fully paid and non-assessable shares of common stock as calculated by
dividing $1.4375 by the Series A Conversion Price (shall initially be $1.4375);
and (iv) vote with the holders of other classes of shares on an as converted
basis.

      As of December 31, 2001, all of the debentures were converted into shares
of the Company's common stock.

Recent Developments

      In December 2002, we entered into a contract with the U.S. Army to develop
a drug to treat Smallpox. The effective date of the contract is January 1, 2003.
The contract is for a period of four years for a total of approximately $1.6
million. Payment over the term of the agreement will be approximately $400,000
per year.

      In February 2003, we entered into a market contract with the Four Star
Group. Four Star will work on our behalf to obtain additional government
contracts and grants. Under the contract, we make certain cash payments for
their services and, if they are successful in obtaining new government funding,
they will receive warrants to purchase shares of our stock. The number of
warrants they can receive will depend on the amount of any contract and grant
funding they obtain. We have the right to cancel the agreement after six months.

      In March 2003, we entered into a non-binding letter of intent to acquire
substantially all of the assets of Plexus Vaccines, Inc. ("Plexus"). The
transaction is subject to certain conditions, including, without limitation, the
completion of due diligence and the negotiation and execution of definitive
agreements. As part of the agreement, we have pursuant to a promissory note made
a loan to Plexus in the amount of $50,000. If the transaction is not completed
by November 30, 2003 or if certain other events occur the loan plus accrued
interest is to be repaid to SIGA.

                                     - 17 -
<PAGE>

Item 6. Management's Discussion and Analysis of Financial Condition and Results
of Operations

      The following discussion should be read in conjunction with our financial
statements and notes to those statements and other financial information
appearing elsewhere in this Annual Report. In addition to historical
information, the following discussion and other parts of this Annual Report
contain forward-looking information that involves risks and uncertainties.

Overview

      We are a development stage biotechnology company, whose primary focus is
on biopharmaceutical product development. Since inception in December 1995 our
efforts have been principally devoted to research and development, securing
patent protection, obtaining corporate relationships and raising capital. Since
inception through December 31, 2002, we have sustained cumulative net losses of
$29,531,402, including non-cash charges in the amount of $1,457,458 for the
write-off of research and development expenses associated with the acquisition
of certain technology rights acquired from a third party in exchange for our
common stock. In addition, a non-cash charge of $2,996,784 was incurred for
stock option and warrant compensation expense. Our losses have resulted
primarily from expenditures incurred in connection with research and
development, patent preparation and prosecution and general and administrative
expenses. From inception through December 31, 2002, research and development
expenses amounted to $13,775,444, patent preparation and prosecution expenses
totaled $1,459,454, general and administration expenses amounted to $17,221,915.
From inception through December 31, 2002 revenues from research and development
agreements and government grants totaled $3,631,631.

      Since inception, SIGA has had limited resources, has incurred cumulative
net operating losses of $29,531,402 and expects to incur additional losses to
perform further research and development activities. We do not have commercial
biomedical products, and we do not expect to have such for several years, if at
all. We believe that we will need additional funds to complete the development
of our biomedical products. Our plans with regard to these matters include
continued development of our products as well as seeking additional research
support funds and financial arrangements. Although we continue to pursue these
plans, there is no assurance that we will be successful in obtaining sufficient
financing on terms acceptable to us. The financial statements do not include any
adjustments that might result from the outcome of this uncertainty. Management
believes it has sufficient funds to support operations through the first quarter
of 2004.

      Our biotechnology operations are run out of our research facility in
Corvallis, Oregon. We continue to seek to fund a major portion of our ongoing
vaccine and antibiotic programs through a combination of government grants and
strategic alliances. While we have had success in obtaining strategic alliances
and grants, no assurance can be given that we will continue to be successful in
obtaining funds from these sources. Until additional relationships are
established, we expect to continue to incur significant research and development
costs and costs associated with the manufacturing of product for use in clinical
trials and pre-clinical testing. It is expected that general and administrative
costs, including patent and regulatory costs, necessary to support clinical
trials and research and development will continue to be significant in the
future.

      To date, we have not marketed, or generated revenues from the commercial
sale of any products. Our biopharmaceutical product candidates are not expected
to be commercially available for several years, if at all. Accordingly, we
expect to incur operating losses for the foreseeable future. There can be no
assurance that we will ever achieve profitable operations.

Significant Accounting Policies

      Financial Reporting Release No. 60, requires all companies to include a
discussion of critical accounting policies or methods used in the preparation of
financial statements. Note 2 of the Notes to the Financial Statements include a
summary of the significant accounting policies and methods used in the
preparation of our Financial Statements. The following is a brief discussion of
the more significant accounting policies and methods used by us. In addition,
Financial Reporting Release No. 61 was released by the SEC to require all
companies to


                                     - 18 -
<PAGE>

include a discussion to address, among other things, liquidity, off-balance
sheet arrangements, contractual obligations and commercial commitments.

   Revenue Recognition

      The Company recognizes revenue in accordance with SEC Staff Accounting
Bulletin No. 101, Revenue Recognition in Financial Statements (SAB 101), as
amended by SAB 101A and 101B. SAB 101 requires that four basic criteria must be
met before revenue can be recognized: (1) persuasive evidence of an arrangement
exists; (2) delivery has occurred or services rendered; (3) the fee is fixed and
determinable; and (4) collectibility is reasonably assured. Under the provisions
of SAB 101 the Company recognizes revenue from government research grants,
contract research and development and progress payments as services are
performed, provided a contractual arrangement exists, the contract price is
fixed or determinable, and the collection of the resulting receivable is
probable. Milestones, which generally are related to substantial scientific or
technical achievement, are recognized in revenue when the milestone is
accomplished.

   Valuation of Investments

      We periodically review the carrying value of our investments for continued
appropriateness. This review is based upon our projections of anticipated future
cash flows. While we believe that our estimates of future cash flows are
reasonable, different assumptions regarding such cash flows could materially
affect our evaluations.

    Off-Balance Sheet Arrangements

      SIGA does not have any significant off-balance sheet arrangements.

Results of Operations

Twelve Months ended December 31, 2002 and December 31, 2001.

      Revenues from grants and research and development contracts were $344,450
for the twelve months ended December 31, 2002 compared to $1,159,500 for the
same period of 2001, an approximate 70% decrease. Revenue for the twelve months
ended December 31, 2001 included recognition of $562,500 from payments made by
Wyeth that had been made to fund research in prior periods and were recorded as
deferred revenue pending signing of a contract extension. In total, $1,025,000
of revenue recorded for the twelve months ended December 31, 2001 was received
from Wyeth. For the twelve months ended December 31, 2002 revenue was comprised
primarily of approximately $270,000 from a Phase II Small Business Innovation
Research ("SBIR") grant and $75,000 received under a sub-contract with Oregon
State University. In December 2002, we entered into a contract with the U.S.
Army to develop a drug to treat Smallpox. The contract is a four year agreement
for approximately $1.6 million with an average annual payment to us of
approximately $400,000. The contract became effective on January 1, 2003.

      General and administrative expenses for the twelve months ended December
31, 2002 were $1,838,470, a decrease of approximately 28% from an expense of
$2,570,869 for the twelve months ended December 31, 2001. Included in the
expenses for the twelve months ended December 31, 2001 was a non-cash charge of
$612,750 to reflect the granting of options to directors with an exercise price
that was less than the fair market value of our shares at the time of the grant.
Excluding these charges, general and administrative expenses for the twelve
months ended December 31, 2002 were approximately $120,000 less than the same
period of the prior year. Payroll expenses declined by 52.1% as a result of
reduction of executive management staff, professional fees were approximately
31% higher in the twelve months ended December 31, 2002 compared to the same
period of 2001 due to the charges incurred as the result of a potential merger.



                                     - 19 -
<PAGE>

      Research and development expenses increased approximately 2% to $1,766,368
for the twelve months ended December 31, 2002 from $1,733,188 for the same
period in 2001. There were no significant changes in the pattern of expenses
between the two twelve month periods. All of our product programs are in the
early stage of development except for the strep vaccine which is in Phase I
clinical trial. At this stage of development, we can not make estimates of the
potential cost for any program to be completed or the time it will take to
complete the project. We do not track the costs of each product program except
for portions of the development program that is being funded by NIH grants. The
risk of completion of any program is high risk because of the long lead time to
program completion and uncertainty of the costs. Net cash inflows from any
products developed from these programs is at least two to three years away.
However, we could receive additional grants, contracts or technology licenses in
the short-term. The potential cash and timing is not known and we can not be
certain if they will ever occur.

      Patent preparation expense for the twelve months ended December 31, 2002
were $104,700 compared to $117,264 for the twelve months ended December 31,
2001. The $12,564 or approximate 11% decrease does not reflect any significant
change in our patent preparation activities.

      Total operating loss for the twelve months ended December 31, 2002 was
$3,365,088 an approximate 3% increase from the $3,261,821 loss incurred for the
twelve months ended December 31, 2001. The increase in the loss is the result of
lower revenue recognition in the 2002 period, offset by the reduction in
operating expenses.

      Net interest income was $34,061 for the twelve months ended December 31,
2002 compared to interest expense of $192,679 for the twelve months ended
December 31, 2001. The improvement is a result of the conversion of the
remainder of the $1,500,000 principle amount of the 6% convertible debenture and
accrued interest during the twelve months ended December 31, 2001.

      During the twelve months ended December 31, 2001 the company recorded a
charge of $275,106 for the impairment of an investment associated with its
interest in Open-i Media.

Quarterly Results of Operations

      The following table sets forth selected unaudited quarterly statements of
operations data, in dollar amounts and as percentages of net revenue, for the
four quarters ended December 31, 2001 and for the four quarters ended December
31, 2002. This information has been prepared substantially on the same basis as
the audited financial statements appearing elsewhere in this annual statement,
and all necessary adjustments, consisting only of normal recurring adjustments,
have been included in the amounts stated below to present fairly the unaudited
quarterly results of operations data. The quarterly data should be read with our
financial statement and then noted to those statements appearing elsewhere in
the annual statement.

2001
  ($ in 000's)                     Q1          Q2           Q3            Q4
                                --------    --------     --------      --------
    Revenue                      $ 305       $ 683       $   158       $    15
        G&A                      $  65       $ 635       $ 1,259       $   611
            % of Revenue            21%         93%          797%        4,073%
    R&D                          $ 431       $ 429       $   498       $   376
        % of Revenue               141%         63%          315%        2,507%
    Patent Prep. Costs           $  18       $  63       $   (11)      $    47
        % of Revenue                 6%          9%           (7)%         313%
    Operating Loss               $ 209       $ 445       $ 1,588       $ 1,019
        % of Revenue                69%         65%        1,005%        6,793%
    Net Loss                     $ 368       $ 520       $ 1,591       $ 1,251
        % of Revenue               121%         76%        1,007%        8,340%
    Basic and
        diluted loss
        per share                (0.05)      (0.07)        (0.19)        (0.13)



                                     - 20 -
<PAGE>

2002
  ($ in 000's)                     Q1          Q2           Q3            Q4
                                --------    --------     --------      --------
    Revenue                      $   0       $ 139       $    90       $   115
        G&A                      $ 341       $ 668       $   273       $   556
        % of Revenue                NA         480%          305%          483%
    R&D                          $ 357       $ 414       $   424       $   571
        % of Revenue                NA         297%          472%          497%
    Patent Prep. Costs           $  27       $  18       $    27       $    33
        % of Revenue                NA          13%           30%           29%
    Operating Loss               $ 725       $ 961       $   634       $ 1,045
        % of Revenue                NA         689%          704%          909%
    Net Loss                     $ 712       $ 951       $   630       $ 1,038
        % of Revenue                NA         683%          700%          902%
    Basic and
        diluted loss
        per share                (0.07)      (0.09)        (0.06)        (0.10)

Liquidity and Capital Resources

      As of December 31, 2002 we had $2,069,004 in cash and cash equivalents. In
addition, we had stock subscriptions outstanding of $791,940 from a private
placement of our common shares that closed in December 2002 and January 2003.

      In March 2002, we signed a non-binding letter of intent to acquire all of
the outstanding shares of Allergy Therapeutics (Holdings) Limited in a stock for
stock transaction. In July 2002, the letter of intent was terminated due to
changes in market conditions. We incurred approximately $600,000 of expenses in
connection with this contemplated transaction. Approximately $200,000 of these
expenses remains unpaid.

      In June 2002, we received an SBIR grant from the NIH. The grant is for
approximately $865,000 to support research over a two year period. Of the total
grant, approximately $521,000 has been allotted for work to be performed in the
first twelve months of the grant. During the twelve months ended December 31,
2002, we recorded revenue in the amount of $270,000.

      In December 2002, we were awarded an initial U.S. government contract with
the U.S. Army to develop an effective Smallpox antiviral drug. The total
estimated revenue under the contract is $1.6 million for the periods January 1,
2003 to May 31, 2007.

      In October 2002, we entered into a collaborative research agreement with
TransTech Pharma, Inc. for the discovery and treatment of human diseases. Under
the terms of the agreement, Trans Tech and SIGA have agreed to contribute their
respective services and products and share in equal costs of specified research
projects. In consideration of the services performed by Trans Tech and use of
its proprietary technology, we granted an exclusive, fully-paid,
nontransferable, nonsublicenseable, limited license to use existing rights to
patents and technologies. We will share equally in the ownership of compounds
and related intellectual property derived from such research efforts.

      In December 2002, we raised gross proceeds of $1.865 million in a private
offering of common stock and warrants to purchase our common stock. We sold
1,700,000 shares of common stock in this offering. In connection with the
offering we issued 171,216 warrants to purchase shares of our common stock to
consultants. The warrants are initially exercisable at a price of $1.65 per
share and have a term of five years. The fair value of the warrants on the date
of grant was approximately $188,970. We received net proceeds from the offering
of $891,000 prior to December 31, 2002 and net proceeds of $791,940 after
December 31, 2002.



                                     - 21 -
<PAGE>

      In October 2002, we raised gross proceeds of $1.04 million in a private
offering of common stock and warrants to purchase our common stock. We sold
1,037,500 shares of common stock and 518,750 warrants. These warrants are
initially exercisable at $2.25 per share and have a term of five years. We
received net proceeds of approximately $935,000. In connection with the offering
we issued another 103,750 warrants to purchase shares of our common stock to
consultants. The consultants' warrants are initially exercisable at a price of
$1.50 per share and have a term of five years.

      In March 2003 we entered into a non-binding letter of intent to acquire
substantially all of the assets of Plexus Vaccines, Inc. ("Plexus"). The
transaction is subject to certain conditions, including, without limitation, the
completion of due diligence and the negotiation and execution of definitive
agreements. As part of the agreement, we have pursuant to a promissory note made
a loan to Plexus in the amount of $50,000. If the transaction is not completed
by November 30, 2003 or if certain other events occur the loan plus accrued
interest is to be repaid to SIGA.

      We anticipate that our current resources will be sufficient to finance our
currently anticipated needs for operating and capital expenditures approximately
through the first quarter of 2004. In addition, we will attempt to generate
additional working capital through a combination of collaborative agreements,
strategic alliances, research grants, equity and debt financing. However, no
assurance can be provided that additional capital will be obtained through these
sources or, if obtained, will be on commercially reasonable terms.

      Our working capital and capital requirements will depend upon numerous
factors, including pharmaceutical research and development programs;
pre-clinical and clinical testing; timing and cost of obtaining regulatory
approvals; levels of resources that we devote to the development of
manufacturing and marketing capabilities; technological advances; status of
competitors; and our ability to establish collaborative arrangements with other
organizations.

      SIGA leases certain facilities and office space under operating leases.
Minimum future rental commitments under operating leases having noncancellable
lease terms are $164,115 $173,821 and $66,982 for the years ending December 31,
2003, 2004 and 2005, respectively. Future minimum leases payments for equipment
under capital leases amount to $11,326 for the year ended December 31, 2003.

Risk Factors That May Affect Results of Operations and Financial Condition

      This report contains forward-looking statements and other prospective
information relating to future events. These forward-looking statements and
other information are subject to risks and uncertainties that could cause our
actual results to differ materially from our historical results or currently
anticipated results including the following:

      We have incurred operating losses since our inception and expect to incur
net losses and negative cash flow for the foreseeable future. We incurred net
losses of $3.3 million and $3.7 million for the years ended December 31, 2002
and 2001, respectively. As of December 31, 2002 and December 31, 2001, our
accumulated deficit was $29.5 million and $26.2 million, respectively. We expect
to continue to incur significant operating expenditures. However we do not
foresee significant capital expenditures in the near future. We will need to
generate significant revenues to achieve and maintain profitability. SIGA
currently has sufficient operation capital to finance its operations through
approximately the first quarter of 2004. Our annual operating needs vary from
year to year depending upon the amount of revenue generated through grants and
licenses. We do not expect a significant change from our current cash burn rate
which is generally consistent throughout the year in the next fiscal year.

      We cannot guarantee that we will achieve sufficient revenues for
profitability. Even if we do achieve profitability, we cannot guarantee that we
can sustain or increase profitability on a quarterly or annual basis in the
future. If revenues grow slower than we anticipate, or if operating expenses
exceed our expectations or cannot be adjusted accordingly, then our business,
results of operations and financial condition will be materially and adversely
affected. Because our strategy includes acquisitions of other businesses,
acquisition expenses and any cash used to make these acquisitions will reduce
our available cash.

      Our business will suffer if we are unable to raise additional equity
funding. We continue to be dependent on our ability to raise money in the equity
markets. There is no guarantee that we will continue to be successful in raising
such funds. If we are unable to raise additional equity funds, we may be forced
to discontinue or cease certain operations.



                                     - 22 -
<PAGE>

      Our stock price is, and we expect it to remain, volatile, which could
limit investors' ability to sell stock at a profit. The volatile price of our
stock makes it difficult for investors to predict the value of their investment,
to sell shares at a profit at any given time, or to plan purchases and sales in
advance. A variety of factors may affect the market price of our common stock.
These include, but are not limited to:

      o     publicity regarding actual or potential clinical results relating to
            products under development by our competitors or us;

      o     delay or failure in initiating, completing or analyzing pre-clinical
            or clinical trials or the unsatisfactory design or results of these
            trials;

      o     achievement or rejection of regulatory approvals by our competitors
            or us;

      o     announcements of technological innovations or new commercial
            products by our competitors or us;

      o     developments concerning proprietary rights, including patents;

      o     developments concerning our collaborations;

      o     regulatory developments in the United States and foreign countries;

      o     economic or other crises and other external factors;

      o     period-to-period fluctuations in our revenues and other results of
            operations;

      o     changes in financial estimates by securities analysts; and

      o     sales of our common stock.

      Additionally, because there is not a high volume of trading in our stock,
any information about SIGA in the media may result in significant volatility in
our stock price.

      We will not be able to control many of these factors, and we believe that
period-to-period comparisons of our financial results will not necessarily be
indicative of our future performance.

      In addition, the stock market in general, and the market for biotechnology
companies in particular, has experienced extreme price and volume fluctuations
that may have been unrelated or disproportionate to the operating performance of
individual companies. These broad market and industry factors may seriously harm
the market price of our common stock, regardless of our operating performance.

      The following table presents the high and low bid range of our stock for
the past two years.

                                    Bid Range

2001                                             High        Low
                                                ------      ------
First Quarter                                    $4.88       $1.62
Second Quarter                                   $4.48       $1.62
Third Quarter                                    $4.05       $2.24
Fourth Quarter                                   $5.21       $1.91


2002                                             High        Low
                                                ------      ------
First Quarter                                    $2.89       $2.01
Second Quarter                                   $2.63       $0.81
Third Quarter                                    $1.39       $0.65
Fourth Quarter                                   $2.15       $0.65

      We are in various stages of product development and there can be no
assurance of successful commercialization. In general, our research and
development programs are at an early stage of development. The


                                     - 23 -
<PAGE>

strep vaccine program is in Phase I clinical trials. All other programs are in
the pre-clinical stage of development. Our biological warfare defense products
do not need human clinical trials for approval by the FDA. We will need to
perform two animal models and provide safety data for a product to be approved.
Our other products will be subject to the approval guidelines under FDA
regulatory requirements which include a number of phases of testing in humans.

      The FDA has not approved any of our biopharmaceutical product candidates.
Any drug candidates developed by us will require significant additional research
and development efforts, including extensive pre-clinical and clinical testing
and regulatory approval, prior to commercial sale. We cannot be sure our
approach to drug discovery will be effective or will result in the development
of any drug. We cannot expect that any drugs resulting from our research and
development efforts will be commercially available for many years, if at all.

      We have limited experience in conducting pre-clinical testing and clinical
trials. Even if we receive initially positive pre-clinical or clinical results,
such results do not mean that similar results will be obtained in the later
stages of drug development, such as additional pre-clinical testing or human
clinical trials. All of our potential drug candidates are prone to the risks of
failure inherent in pharmaceutical product development, including the
possibility that none of our drug candidates will or can:

      o     be safe, non-toxic and effective;

      o     otherwise meet applicable regulatory standards;

      o     receive the necessary regulatory approvals;

      o     develop into commercially viable drugs;

      o     be manufactured or produced economically and on a large scale;

      o     be successfully marketed;

      o     be reimbursed by government and private insurers; and

      o     achieve customer acceptance.

      In addition, third parties may preclude us from marketing our drugs
through enforcement of their proprietary rights, or third parties may succeed in
marketing equivalent or superior drug products. Our failure to develop safe,
commercially viable drugs would have a material adverse effect on our business,
financial condition and results of operations.

      Most of our immediately foreseeable future revenues are contingent upon
collaborative and license agreements and we may not achieve sufficient revenues
from these agreements to attain profitability. Until and unless we successfully
make a product, our ability to generate revenues will largely depend on our
ability to enter into additional collaborative and license agreements with third
parties and maintain the agreements we currently have in place. We will receive
little or no revenues under our collaborative agreements if our collaborators'
research, development or marketing efforts are unsuccessful, or if our
agreements are terminated early. Additionally, if we do not enter into new
collaborative agreements, we will not receive future revenues from new sources.
Our future revenue is substantially dependent on the continuing grant and
contract work being performed for the NIH which expires in May 2004 and the U.S.
Army which expires at the end of December 2007. These agreements are for
specific work to be performed under the agreements and could only be cancelled
for non-performance.

      Several factors will affect our future receipt of revenues from
collaborative arrangements, including the amount of time and effort expended by
our collaborators, the timing of the identification of useful drug targets and
the timing of the discovery and development of drug candidates. Under our
existing agreements, we may not earn significant milestone payments until our
collaborators have advanced products into clinical testing, which may not occur
for many years, if at all.



                                     - 24 -
<PAGE>

      We may not find sufficient acquisition candidates to implement our
business strategy. As part of our business strategy we expect to enter into
business combinations and acquisitions. We compete for acquisition candidates
with other entities, some of which have greater financial and other resources
than we have. Increased competition for acquisition candidates may make fewer
acquisition candidates available to us and may cause acquisitions to be made on
less attractive terms, such as higher purchase prices. Acquisition costs may
increase to levels that are beyond our financial capability or that would
adversely affect our results of operations and financial condition. Our ability
to make acquisitions will depend in part on the relative attractiveness of
shares of our common stock as consideration for potential acquisition
candidates. This attractiveness may depend largely on the relative market price,
our ability to register common stock and capital appreciation prospects of our
common stock. If the market price of our common stock were to decline materially
over a prolonged period of time, our acquisition program could be materially
adversely affected.

      We may face limitations on our ability to attract suitable acquisition
opportunities or to integrate additional acquired businesses and the failure to
consummate an acquisition may significantly drain our resources. As part of our
business strategy we expect to enter into business combinations and
acquisitions. Some of these transactions could be material in size and scope.
While we will continually be searching for additional acquisition opportunities,
we may not be successful in identifying suitable acquisitions. We compete for
acquisition candidates with other entities, some of which have greater financial
and other resources than we have. Increased competition for acquisition
candidates may make fewer acquisition candidates available to us and may cause
acquisitions to be made on less attractive terms, such as higher purchase
prices. Acquisition costs may increase to levels that are beyond our financial
capability or that would adversely affect our results of operations and
financial condition. Our ability to make acquisitions will depend in part on the
relative attractiveness of shares of our common stock as consideration for
potential acquisition candidates. This attractiveness may depend largely on the
relative market price, our ability to register common stock and capital
appreciation prospects of our common stock. If the market price of our common
stock were to decline materially over a prolonged period of time, our
acquisition program could be materially adversely affected. Failure to making an
acquisition will limit our ability to grow, but will not be central to our
continued existence. Costs associated with failed acquisitions, such as our
plans to merge with Allergy Therapeutics and Hypernix, may result in significant
operating costs that may need to be financed from operations or from additional
equity capital. The total costs associated with the failed acquisition of
Allergy Therapeutics were approximately $625,000, of which approximately
$200,000 remain unpaid. The costs were associated with professional fees for
attorneys and accountants. Additionally, there was significant time spent by our
management in the contemplated transaction. The proposed Hypernix transaction
resulted in expenses of $511,000 for advances made to them. We recovered
approximately $85,000 from them.

      We may not be able to consummate potential acquisitions or an acquisition
may not enhance our business or may decrease rather than increase our earnings.
In the future, we may issue additional securities in connection with one or more
acquisitions, which may dilute our existing shareholders. Future acquisitions
could also divert substantial management time and result in short term
reductions in earnings or special transaction or other charges. In addition, we
cannot guarantee that we will be able to successfully integrate the businesses
that we may acquire into our existing business. Our shareholders may not have
the opportunity to review, vote on or evaluate future acquisitions.

      The biopharmaceutical market in which we compete and will compete is
highly competitive. The biopharmaceutical industry is characterized by rapid and
significant technological change. Our success will depend on our ability to
develop and apply our technologies in the design and development of our product
candidates and to establish and maintain a market for our product candidates.
There also are many companies, both public and private, including major
pharmaceutical and chemical companies, specialized biotechnology firms,
universities and other research institutions engaged in developing
pharmaceutical and biotechnology products. Many of these companies have
substantially greater financial, technical, research and development, and human
resources than us. Competitors may develop products or other technologies that
are more effective than any that are being developed by us or may obtain FDA
approval for products more rapidly than us. If we commence commercial sales of
products, we still must compete in the manufacturing and marketing of such
products, areas in which we have no experience. Many of these companies also
have manufacturing facilities and established marketing capabilities that would
enable such companies to market competing products through existing channels of
distribution. Two companies with similar profiles are VaxGen, Inc. which is
developing vaccines against anthrax, Smallpox and HIV/AIDS; and Avant
Immunotherapeutics, Inc. which has vaccine programs for agents of biological
warfare.

                                     - 25 -
<PAGE>

      Because we must obtain regulatory clearance to test and market our
products in the United States, we cannot predict whether or when we will be
permitted to commercialize our products. A pharmaceutical product cannot be
marketed in the U.S. until it has completed rigorous pre-clinical testing and
clinical trials and an extensive regulatory clearance process implemented by the
FDA. Pharmaceutical products typically take many years to satisfy regulatory
requirements and require the expenditure of substantial resources depending on
the type, complexity and novelty of the product.

      Before commencing clinical trials in humans, we must submit and receive
clearance from the FDA by means of an Investigational New Drug ("IND")
application. Institutional review boards and the FDA oversee clinical trials and
such trials:

      o     must be conducted in conformance with the FDA's good laboratory
            practice regulations;

      o     must meet requirements for institutional review board oversight;

      o     must meet requirements for informed consent;

      o     must meet requirements for good clinical and manufacturing
            practices;

      o     are subject to continuing FDA oversight;

      o     may require large numbers of test subjects; and

      o     may be suspended by us or the FDA at any time if it is believed that
            the subjects participating in these trials are being exposed to
            unacceptable health risks or if the FDA finds deficiencies in the
            IND application or the conduct of these trials.

      Before receiving FDA clearance to market a product, we must demonstrate
that the product is safe and effective on the patient population that will be
treated. Data we obtain from preclinical and clinical activities are susceptible
to varying interpretations that could delay, limit or prevent regulatory
clearances. Additionally, we have limited experience in conducting and managing
the clinical trials and manufacturing processes necessary to obtain regulatory
clearance.

      If regulatory clearance of a product is granted, this clearance will be
limited only to those states and conditions for which the product is
demonstrated through clinical trials to be safe and efficacious. We cannot
ensure that any compound developed by us, alone or with others, will prove to be
safe and efficacious in clinical trials and will meet all of the applicable
regulatory requirements needed to receive marketing clearance.

      If our technologies or those of our collaborators are alleged or found to
infringe the patents or proprietary rights of others, we may be sued or have to
license those rights from others on unfavorable terms. Our commercial success
will depend significantly on our ability to operate without infringing the
patents and proprietary rights of third parties. Our technologies, along with
our licensors' and our collaborators' technologies, may infringe the patents or
proprietary rights of others. If there is an adverse outcome in litigation or an
interference to determine priority or other proceeding in a court or patent
office, then we, or our collaborators an licensors, could be subjected to
significant liabilities, required be license disputed rights from or to other
parties and/or required to cease using a technology necessary to carry out
research, development and commercialization. At present we are unaware of any or
potential infringement claims against our patent portfolio.

      The costs to establish the validity of patents, to defend against patent
infringement claims of others and to assert infringement claims against others
can be expensive and time consuming, even if the outcome is favorable. An
outcome of any patent prosecution or litigation that is unfavorable to us or one
of our licensors or collaborators may have a material adverse effect on us. We
could incur substantial costs if we are required to defend ourselves in patent
suits brought by third parties, if we participate in patent suits brought
against or initiated by our licensors or collaborators or if we initiate such
suits. We may not have sufficient funds or resources in the event of litigation.
Additionally, we may not prevail in any such action.



                                     - 26 -
<PAGE>

      Any conflicts resulting from third-party patent applications and patents
could significantly reduce the coverage of the patents owned, optioned by or
licensed to us or our collaborators and limit our ability or that of our
collaborators to obtain meaningful patent protection. If patents are issued to
third parties that contain competitive or conflicting claims, we, our licensors
or our collaborators may be legally prohibited from researching, developing or
commercializing of potential products or be required to obtain licenses to these
patents or to develop or obtain alternative technology. We, our licensors and/or
our collaborators may be legally prohibited from using patented technology, may
not be able to obtain any license to the patents and technologies of third
parties on acceptable terms, if at all, or may not be able to obtain or develop
alternative technologies.

      In addition, like many biopharmaceutical companies, we may from time to
time hire scientific personnel formerly employed by other companies involved in
one or more areas similar to the activities conducted by us. We and/or these
individuals may be subject to allegations of trade secret misappropriation or
other similar claims as a result of their prior affiliations.

      Our ability to compete may decrease if we do not adequately protect our
intellectual property rights. Our commercial success will depend in part on our
and our collaborators' ability to obtain and maintain patent protection for our
proprietary technologies, drug targets and potential products and to effectively
preserve our trade secrets. Because of the substantial length of time and
expense associated with bringing potential products through the development and
regulatory clearance processes to reach the marketplace, the pharmaceutical
industry places considerable importance on obtaining patent and trade secret
protection. The patent positions of pharmaceutical and biotechnology companies
can be highly uncertain and involve complex legal and factual questions. No
consistent policy regarding the breadth of claims allowed in biotechnology
patents has emerged to date. Accordingly, we cannot predict the type and breadth
of claims allowed in these patents.

      We also rely on copyright protection, trade secrets, know-how, continuing
technological innovation and licensing opportunities. In an effort to maintain
the confidentiality and ownership of trade secrets and proprietary information,
we require our employees, consultants and some collaborators to execute
confidentiality and invention assignment agreements upon commencement of a
relationship with us. These agreements may not provide meaningful protection for
our trade secrets, confidential information or inventions in the event of
unauthorized use or disclosure of such information, and adequate remedies may
not exist in the event of such unauthorized use or disclosure.

      We may have difficulty managing our growth. We expect to experience growth
in the number of our employees and the scope of our operations. This growth has
placed, and may continue to place, a significant strain on our management and
operations. Our ability to manage this growth will depend upon our ability to
broaden our management team and our ability to attract, hire and retain skilled
employees. Our success will also depend on the ability of our officers and key
employees to continue to implement and improve our operational and other systems
and to hire, train and manage our employees.

      We depend on a key employee in a competitive market for skilled personnel.
We are highly dependent on a principal member of our scientific staff. The loss
of his services would have a material adverse effect on our business. We
currently have an employment agreement with the individual who we consider to be
a "key employee." We do not maintain a key person life insurance policy on the
life of any employee.

      Dr. Dennis E. Hruby, our Chief Scientific Officer is employed under a
contract that is in force through December 31, 2005.

      Our future success also will depend in part on the continued service of
our key scientific, software, bioinformatics and management personnel and our
ability to identify, hire and retain additional personnel, including customer
service, marketing and sales staff. We experience intense competition for
qualified personnel. We may not be able to continue to attract and retain
personnel necessary to develop our business.

      Our activities involve hazardous materials and may subject us to
environmental regulatory liabilities. Our biopharmaceutical research and
development involves the controlled use of hazardous and radioactive materials

                                     - 27 -
<PAGE>

and biological waste. We are subject to federal, state and local laws and
regulations governing the use, manufacture, storage, handling and disposal of
these materials and certain waste products. Although we believe that our safety
procedures for handling and disposing of these materials comply with legally
prescribed standards, the risk of accidental contamination or injury from these
materials cannot be completely eliminated. In the event of an accident, we could
be held liable for damages, and this liability could exceed our resources. The
research and development activities of our company do not produce any unusual
hazardous products. We do use small amounts of 32P, 35S and 3H, which are stored
used and disposed of in accordance with Nuclear Regulatory Commission ("NRC ")
regulations. We maintain liability insurance in the amount of approximately
$3,000,000 and we believe this should be sufficient to cover any contingent
losses.

      We believe that we are in compliance in all material respects with
applicable environmental laws and regulations and currently do not expect to
make material additional capital expenditures for environmental control
facilities in the near term. However, we may have to incur significant costs to
comply with current or future environmental laws and regulations.

      Our potential products may not be acceptable in the market or eligible for
third party reimbursement resulting in a negative impact on our future financial
results. Any products successfully developed by us or our collaborative partners
may not achieve market acceptance. The antibiotic products which we are
attempting to develop will compete with a number of well-established traditional
antibiotic drugs manufactured and marketed by major pharmaceutical companies.
The degree of market acceptance of any of our products will depend on a number
of factors, including:

      o     the establishment and demonstration in the medical community of the
            clinical efficacy and safety of such products,

      o     the potential advantage of such products over existing treatment
            methods, and

      o     reimbursement policies of government and third-party payors.


      Physicians, patients or the medical community in general may not accept or
utilize any products that we or our collaborative partners may develop. Our
ability to receive revenues and income with respect to drugs, if any, developed
through the use of our technology will depend, in part, upon the extent to which
reimbursement for the cost of such drugs will be available from third-party
payors, such as government health administration authorities, private health
care insurers, health maintenance organizations, pharmacy benefits management
companies and other organizations. Third-party payors are increasingly disputing
the prices charged for pharmaceutical products. If third-party reimbursement was
not available or sufficient to allow profitable price levels to be maintained
for drugs developed by us or our collaborative partners, it could adversely
affect our business.

      If our products harm people, we may experience product liability claims
that may not be covered by insurance. We face an inherent business risk of
exposure to potential product liability claims in the event that drugs we
develop are alleged to cause adverse effects on patients. Such risk exists for
products being tested in human clinical trials, as well as products that receive
regulatory approval for commercial sale. We may seek to obtain product liability
insurance with respect to drugs we and/or or our collaborative partners develop.
However, we may not be able to obtain such insurance. Even if such insurance is
obtainable, it may not be available at a reasonable cost or in a sufficient
amount to protect us against liability.

      We may be required to perform additional clinical trials or change the
labeling of our products if we or others identify side effects after our
products are on the market, which could harm sales of the affected products. If
we or others identify side effects after any of our products, if any, after they
are on the market, or if manufacturing problems occur:

      o     regulatory approval may be withdrawn;

      o     reformulation of our products, additional clinical trials, changes
            in labeling of our products may be required;



                                     - 28 -
<PAGE>

      o     changes to or re-approvals of our manufacturing facilities may be
            required;

      o     sales of the affected products may drop significantly;

      o     our reputation in the marketplace may suffer; and

      o     lawsuits, including class action suits, may be brought against us.

      Any of the above occurrences could harm or prevent sales of the affected
products or could increase the costs and expenses of commercializing and
marketing these products.

      Difficult Manufacturing Requirements. The manufacture of genetically
engineered commensals is a time-consuming and complex process. Our management
believes that we have the ability to acquire or produce quantities of
genetically engineered commensals sufficient to support our present needs for
research and our projected needs for our initial clinical development programs.
However, we believe that improvements in our manufacturing technology will be
required to enable us to meet the volume and cost requirements needed for
certain commercial applications of commensal products. Products based on
commensals have never been manufactured on a commercial scale. The manufacture
of all of our products will be subject to current GMP requirements prescribed by
the FDA or other standards prescribed by the appropriate regulatory agency in
the country of use. There can be no assurance that we will be able to
manufacture products, or have products manufactured for us, in a timely fashion
at acceptable quality and prices, that we or third party manufacturers can
comply with GMP or that we or third party manufacturers will be able to
manufacture an adequate supply of product.

      Health care reform and controls on health care spending may limit the
price we charge for any products and the amounts thereof that we can sell. The
U.S. federal government and private insurers have considered ways to change, and
have changed, the manner in which health care services are provided in the U.S.
Potential approaches and changes in recent years include controls on health care
spending and the creation of large purchasing groups. In the future, the U.S.
government may institute further controls and limits on Medicare and Medicaid
spending. These controls and limits might affect the payments we could collect
from sales of any products. Uncertainties regarding future health care reform
and private market practices could adversely affect our ability to sell any
products profitably in the U.S. At present, we do not foresee any changes in FDA
regulatory policies that would adversely effect our development programs.

      The future issuance of preferred stock may adversely effect the rights of
the holders of our common stock. Our certificate of incorporation allows our
Board of Directors to issue up to 10,000,000 shares of preferred stock and to
fix the voting powers, designations, preferences, rights and qualifications,
limitations or restrictions of these shares without any further vote or action
by the stockholders. The rights of the holders of common stock will be subject
to, and could be adversely affected by, the rights of the holders of any
preferred stock that we may issue in the future. The issuance of preferred
stock, while providing desirable flexibility in connection with possible
acquisitions and other corporate purposes, could have the effect of making it
more difficult for a third party to acquire a majority of our outstanding voting
stock, thereby delaying, deferring or preventing a change in control.

      Concentration of ownership of our capital stock could delay or prevent
change of control. Our directors, executive officers and principal stockholders
beneficially own a significant percentage of our common stock and preferred
stock. They also have, through the exercise or conversion of certain securities,
the right to acquire additional common stock. As a result, these stockholders,
if acting together, have the ability to significantly influence the outcome of
corporate actions requiring shareholder approval. Additionally, this
concentration of ownership may have the effect of delaying or preventing a
change in control of SIGA. At December 31, 2002, Directors, Officers and
principal stockholders beneficially own approximately 37% of the our stock.

Item 7. Financial Statements and Supplementary Data

      The financial statements required by Item 7 are included in this Annual
Report beginning on Page F-1.




                                     - 29 -
<PAGE>

Item 8. Changes in and Disagreements with Accountants on Accounting and
        Financial Disclosure

      None.




                                     - 30 -
<PAGE>

                                    PART III

Item 9.  Directors and Executive Officers of the Registrant

Name                       Age          Position
-----                     ----          --------
Donald G. Drapkin          55           Chairman of the Board
Thomas N. Konatich         57           Acting Chief Executive Officer, Chief
                                        Financial Officer, Secretary
                                        and Treasurer
Dennis E. Hruby, Ph.D.     51           Chief Scientific Officer
Gabriel M. Cerrone         31           Director
Thomas E. Constance        66           Director
Mehmet C. Oz, M.D.         41           Director
Eric A. Rose, M.D.         51           Director
Michael Weiner, M.D.       56           Director

      Donald G. Drapkin has served as Chairman of the Board and a Director of
SIGA since April 19, 2001. Mr. Drapkin has been a Director and Vice Chairman of
MacAndrews & Forbes Holdings Inc. and various of its affiliates since 1987.
Prior to joining MacAndrews & Forbes, Mr. Drapkin was a partner in the law firm
of Skadden, Arps, Slate, Meagher & Flom LLP. Mr. Drapkin is also a Director of
the following corporations which file reports pursuant to the Securities
Exchange Act of 1934: Anthracite Capital, Inc., BlackRock Asset Investors, The
Molson Companies Limited, Panavision, Inc., Playboy.com, Inc., Playboy
Enterprises, Inc., Revlon Consumer Products Corporation, Revlon Inc., and the
Warnaco Group, Inc. Mr. Drapkin is a Director of American Lawyer Media, Inc.,
Pharmacore, Inc., and TransTech Pharma, Inc. and WeddingChannel.com.

      Thomas N. Konatich has served as Vice President, Chief Financial Officer
and Treasurer since April 1, 1998. He was named Secretary of SIGA on June 29,
2001 and has been our Acting Chief Executive Officer since October 5, 2001. From
November 1996 through March 1998, Mr. Konatich served as Chief Financial Officer
and a Director of Innapharma, Inc., a privately held pharmaceutical development
company. From 1993 through November 1996, Mr. Konatich served as Vice President
and Chief Financial Officer of Seragen, Inc., a publicly traded
biopharmaceutical development company. From 1988 to 1993, he was Treasurer of
Ohmicron Corporation, a venture capital financed environmental biotechnology
firm. Mr. Konatich has an MBA from the Columbia Graduate School of Business.

      Dennis F. Hruby, Ph.D. has served as Vice-President - Chief Scientific
Officer since June 2000. From April 1, 1997 through June 2000 Dr. Hruby was our
Vice President of Research. From January 1996 through March 1997, Dr. Hruby
served as a senior scientific advisor to SIGA. Dr. Hruby is a Professor of
Microbiology at Oregon State University, and from 1990 to 1993 was Director of
the Molecular and Cellular Biology Program and Associate Director of the Center
for Gene Research and Biotechnology. Dr. Hruby specializes in virology and cell
biology research, and the use of viral and bacterial vectors to produce
recombinant vaccines. He is a member of the American Society of Virology, the
American Society for Microbiology and a fellow of the American Academy of
Microbiology. Dr. Hruby received a Ph.D. in microbiology from the University of
Colorado Medical Center and a B.S. in microbiology from Oregon State University.

      Gabriel M. Cerrone has served as a Director of SIGA since April 19, 2001.
Mr. Cerrone has been Senior Vice President of Investments of Fahnestock & Co.,
Inc., a financial services firm, since March 1999. From March 1998 to March
1999, Mr. Cerrone was Managing Director of Investments at Barington Capital,
L.P., a merchant bank, and, from June 1994 to February 1998, he was Senior Vice
President of Investments at Blair & Company, a financial services firm focusing
on microcap companies. Mr. Cerrone is a Director of the following privately-held
companies: Callisto Pharmaceuticals, Inc. and Macro Holdings, LLC. He is also
the sole general


                                     - 31 -
<PAGE>

partner of Panetta Partners, Ltd., a firm which acts as an investor in, and
consultant to, primarily emerging technology companies. Mr. Cerrone is a 1994
graduate of New York University's Stern School of Business.

      Thomas E. Constance has served as a Director of SIGA since April 19, 2001.
Mr. Constance is Chairman and, since 1994, a partner of Kramer Levin Naftalis &
Frankel LLP, a law firm in New York City. Mr. Constance is a Director of the
following corporations which file reports pursuant to the Securities Exchange
Act of 1934: Uniroyal Technology Corporation and Kroll Inc. Mr. Constance is
also a Director of Callisto Pharmaceuticals, Inc., a privately-held company. Mr.
Constance serves as a Trustee of the M.D. Sass Foundation and St. Vincent's
Services. He also serves on the Advisory Board of Barington Capital, L.P.

      Mehmet C. Oz, M.D. has served as a Director of SIGA since April 19, 2001.
Dr. Oz has been a Cardiac Surgeon at Columbia University Presbyterian Hospital
since 1993 and an Associate Professor of Surgery there since July 2000. Dr. Oz
directs the following programs at Columbia University Presbyterian Hospital: the
Cardiovascular Institute, the complementary medicine program, the clinical
profusion program and clinical trials of new surgical technology. Dr. Oz
received his undergraduate degree from Harvard University in 1982, and, in 1986,
he received a joint M.D./M.B.A. degree from the University of Pennsylvania
Medical School and the Wharton School of Business.

      Eric A. Rose, M.D. has served as a Director of SIGA since April 19, 2001.
From April 19, 2001 until June 21, 2001, Dr. Rose served as Interim Chief
Executive Officer of SIGA. Dr. Rose is currently Chairman of the Department of
Surgery and Surgeon-in-Chief of the Columbia Presbyterian Center of New York
Presbyterian Hospital, a position he has held since August 1994. Dr. Rose is a
past President of the International Society for Heart and Lung Transplantation.
Dr. Rose was recently appointed as Morris & Rose Milstein Professor of Surgery
at Columbia University's College of Physicians and Surgeons' Department of
Surgery. Dr. Rose is also a Director of Nexell Therapeutics Inc. (f/k/a VimRx).
Dr. Rose is a graduate of both Columbia College and Columbia University College
of Physicians & Surgeons.

      Michael Weiner, M.D. has served as a Director of SIGA since April 19,
2001. Dr. Weiner has been a Professor of Pediatrics at Columbia University
College of Physicians and Surgeons since 1996. Dr. Weiner is also the Director
of Pediatric Oncology at New York Presbyterian Hospital. Dr. Weiner was formerly
a Director of Nexell Therapeutics, Inc. (f/k/a VimRx) from March 1996 to
February 1999. Dr. Weiner is a 1972 graduate of the New York State Health
Sciences Center at Syracuse, and he was a post graduate student at New York
University and Johns Hopkins University.

Section 16(a) Beneficial Ownership Reporting Compliance

      Section 16(a) of the Securities Exchange Act of 1934 (the "Exchange Act")
requires the Company's officers and directors, and persons who own more than ten
percent of a registered class of the Company's equity securities, to file
reports of ownership and changes in ownership with the Securities and Exchange
Commission. Officers, directors and greater than ten-percent stockholders are
required by SEC regulation to furnish the Company with copies of all Section
16(a) reports that they file.

      Based solely upon review of the copies of such reports furnished to the
Company and written representations from certain of the Company's executive
officers and directors that no other such reports were required, the Company
believes that during the fiscal year ended December 31, 2002 all Section 16(a)
filing requirements applicable to its officers, directors and greater than
ten-percent beneficial owners were complied with on a timely basis, except that
Mr. Konatich belatedly filed in March 2003 a Form 5 due in January 2003.


                                     - 32 -
<PAGE>

Item 10. Executive Compensation

      The following table sets forth the total compensation paid or accrued for
the years ended December 31, 2002, 2001 and 2000 for each person who acted as
SIGA's Chief Executive Officer at any time during the year ended December 31,
2002 and its most highly compensated executive officers, other than its Chief
Executive Officer, whose salary and bonus for the fiscal year ended December 31,
2002 were in excess of $100,000 each.


                           Summary Compensation Table

<TABLE>
<CAPTION>
                                                                      Annual Compensation
                                                       ---------------------------------------------------
                                                                                            Long-Term
                                                                                           Compensation
                                                                       Other Annual         Securities
                                                                       Compensation     Underlying Options
                                                                       ------------     ------------------
Name and Principal Position                    Year    Salary ($)           ($)               (#)
---------------------------                    ----    ----------          -----            -------
<S>                                            <C>      <C>                  <C>            <C>
Thomas N. Konatich,                            2002     188,333              --             200,000
    Chief Financial Officer and Acting CEO     2001     177,542              --                  --
                                               2000     170,000              --             100,000

Dennis E. Hruby                                2002     195,000              --             300,000
    Chief Scientific Officer                   2001     196,055              --                  --
                                               2000     170,000              --             125,000
</TABLE>

----------

Option Grants for the Year Ended December 31, 2002

      The following table sets forth grants of stock options during the year
ended December 31, 2002 to anyone who served as Chief Executive Officer during
the year. The exercise price at the time of the grant was equal to or above the
fair market value at the time of the grant.

<TABLE>
<CAPTION>
                        Common Stock          % of Total
                         Underlying         Options Granted         Exercise          Expiration
Name                   Options Granted       to Employees       Price Per Share          Date
-----                  ---------------      ---------------     ---------------       ----------
<S>                         <C>                 <C>                 <C>                <C>
Thomas N. Konatich          200,000             25.7%               $   2.50           11/15/12
Dennis E. Hruby             300,000             38.6%               $   2.50           10/15/12
</TABLE>

----------

Option Exercises in Last Fiscal Year and Fiscal Year-End Option Values

      The following table provides certain summary information concerning stock
options held as of December 31, 2002 by SIGA's Chief Executive Officer and its
two most highly compensated executive officers, other than its Chief Executive
Officer. No options were exercised during fiscal 2002 by any of the officers.

<TABLE>
<CAPTION>
                                                                                           Value of Unexercised
                                       Number of Securities Underlying                     In-The-Money Options
                                            Unexercised Options #                      at Fiscal Year-End ($) (1)
                                     ----------------------------------           -------------------------------------
Name                                 Exercisable          Unexercisable           Exercisable             Unexercisable
-----                                -----------          -------------           -----------             -------------
<S>                                    <C>                  <C>                        <C>                     <C>
Thomas N. Konatich                     288,750              106,250                    0                       0
Dennis Hruby                           250,000              225,000                    0                       0
</TABLE>

(1)   Based upon the closing price on December 31, 2002 as reported on the
      Nasdaq SmallCap Market and the exercise price per option.

Stock Option Plan

      As of January 1, 1996, we adopted our 1996 Incentive and Non-Qualified
Stock Option Plan. An amendment and restatement of such plan, as amended, was
adopted on May 3, 2001 and was further refined by the Board of Directors


                                     - 33 -
<PAGE>

on June 29, 2001 (the "Plan"). The Plan was approved by our stockholders at an
annual meeting on August 15, 2001. Stock options may be granted to key
employees, consultants and outside directors pursuant to the Plan.

      The Plan is administered by a committee (the "Committee") comprised of
disinterested directors. The Committee determines persons to be granted stock
options, the amount of stock options to be granted to each such person, and the
terms and conditions of any stock options as permitted under the Plan. The
members of the Committee are Mehmet C. Oz, M.D. and Michael Weiner, M.D.

      Both Incentive Options and Nonqualified Options may be granted under the
Plan. An Incentive Option is intended to qualify as an incentive stock option
within the meaning of Section 422 of the Internal Revenue Code of 1986, as
amended (the "Code"). Any Incentive Option granted under the Plan will have an
exercise price of not less than 100% of the fair market value of the shares on
the date on which such option is granted. With respect to an Incentive Option
granted to an employee who owns more than 10% of the total combined voting stock
of SIGA or of any parent or subsidiary of SIGA, the exercise price for such
option must be at least 110% of the fair market value of the shares subject to
the option on the date the option is granted.

      The Plan, as amended, provides for the granting of options to purchase
7,500,000 shares of common stock, of which 5,807,561 options were outstanding as
of December 31, 2002.

      During the fiscal years ending December 31, 2002, 2001 and 2000, the named
Directors and Officers of SIGA received log-term incentive compensation under
the Plan as shown in the following table.

<TABLE>
<CAPTION>

----------------------------------------------------------------------------------------------------------------------------------
                                                                                          Estimated Future Payouts Under
                                                                                           Non-Stock Price Based Plans
----------------------------------------------------------------------------------------------------------------------------------
     (a)                                  (b)                    (c)                (d)               (e)              (f)
                                                           Performance or
                                   Number of Shares,     Other Period Until
                                 Units or Other Rights      Maturation of        Threshold          Target           Maximum
     Name                                 (#)                  Payout             ($ or #)         ($ or #)          ($ or #)
----------------------------------------------------------------------------------------------------------------------------------
<S>                                    <C>                   <C>                    <C>               <C>              <C>
Donald G. Drapkin                      1,125,000              8/15/11               0                 0                0

Thomas N. Konatich                       300,000             11/15/12               0                 0                0

Gabriel Cerrone                        1,075,000              8/15/11               0                 0                0

Thomas E. Constance                      225,000              8/15/11               0                 0                0

Mehmet C. Oz, M.D                        100,000              8/15/11               0                 0                0

Eric A. Rose, M.D.                       600,000              8/15/11               0                 0                0

Michael Weiner, M.D.                     100,000              8/15/11               0                 0                0

Dennis E. Hruby                          300,000             10/15/12               0                 0                0
----------------------------------------------------------------------------------------------------------------------------------
</TABLE>



                                     - 34 -
<PAGE>

Employment Contracts and Directors Compensation

Employment Contracts

      Thomas N. Konatich, SIGA's Vice President, Chief Financial Officer,
Secretary, Treasurer and Acting Chief Executive Officer, is employed by SIGA
under an employment agreement dated April 1, 1998, as amended on January 19,
2000, as amended and restated on October 6, 2000, as amended as of January 31,
2002 and as amended on November 5, 2002. This Agreement expires on September 30,
2004 and is cancellable by SIGA only for cause, as defined in the agreement. Mr.
Konatich receives an annual base salary of $210,000. He received options to
purchase 95,000 shares of common stock, at $4.44 on April 1, 1998. The options
vested on a pro rata basis on the first, second, third and fourth anniversaries
of the agreement. On January 19, 2000, he received an additional grant to
purchase 100,000 shares at an exercise price of $2.00 per share. These options
vest on a pro rata basis each quarter through January 19, 2002. On January 31,
2002, Mr. Konatich was granted an "Incentive Stock Option" to purchase 50,000
shares at an exercise price of $3.94 per share. Such options vest in eight equal
quarterly installments beginning on April 20, 2002. On November 5, 2002, Mr.
Konatich was granted an Incentive Stock Option to purchase 150,000 shares at an
exercise price of $2.50 per share. 75,000 of these options vested immediately
and 75,000 options vest on September 1, 2003. Mr. Konatich is also eligible to
receive additional stock options and bonuses at the discretion of the Board of
Directors.

      Dr. Dennis Hruby, Chief Scientific Officer ("CSO"), is employed by SIGA
under an employment agreement dated January, 1, 1998, as amended on June 16,
2000, as amended on January 31, 2002, as amended on October 3, 2002. This
Agreement expires on December 31, 2005, except that SIGA may terminate the
agreement upon 180 days written notice. Dr. Hruby receives a base salary of
$210,000 per year. Dr. Hruby received options to purchase 10,000 shares of
common stock at an exercise price of $5.00 per share on April 1, 1997 and 40,000
shares of common stock at an exercise price of $4.63 per share on April 1, 1998.
The options became exercisable on a pro rata basis on the first, second, third
and fourth anniversaries of the agreement. Dr. Hruby is eligible to receive
additional stock options and bonuses at the discretion of the Board of
Directors. Under the June 16, 2000 amendment, Dr. Hruby was granted options to
purchase 125,000 shares of SIGA's common stock at $2.00 per share. The options
vest ratably over the remaining term of the amendment. The January 31, 2002
amendment changed the terms of the lock-up agreed to in the June 16, 2000
amendment to the employment agreement limiting Hruby's ability to sell SIGA
stock. On January 31, 2002 Dr. Hruby was granted and "Incentive Stock Option" to
purchase 50,000 shares at an exercise price of $3.94 per share. Such options
vest in four equal annual installments beginning on August 15, 2002. As part of
the most recent amendment, Dr. Hruby was granted an option to purchase 300,000
shares of common stock. Options with respect to 75,000 shares vested upon the
signing of the amendment and an additional 75,000 shares shall vest on a pro
rata basis on September 1 of each 2003, 2004 and 2005. The options have an
exercise price of $2.50 per share. As part of the amended agreement, Dr. Hruby
surrendered his option to purchase up to 50,000 shares of common stock of SIGA
at an exercise price of $3.94 that he was granted under an earlier amendment.

Directors' Compensation

      SIGA does not pay fees to its directors, nor does it reimburse its
directors for expenses incurred.

Item 11. Security Ownership of Certain Beneficial Owners and Management and
         Related Stockholders Matters

      The following tables set forth certain information regarding the
beneficial ownership of SIGA's voting securities as of December 31, 2002 of (i)
each person known to SIGA to beneficially own more than 5% of the applicable
class of voting securities, (ii) each director and director nominee of SIGA,
(iii) each Named Officer, and (iv) all directors and officers of SIGA as a
group. As of March 13, 2003, a total of 13,226,649 shares of common stock and a
total of 410,760 shares of Series A preferred stock were outstanding. Each share
of common stock and


                                     - 35 -
<PAGE>

Series A preferred stock is entitled to one vote on matters on which common
stockholders are eligible to vote. The column entitled "Percentage of Total
Voting Stock" shows the percentage of total voting stock beneficially owned by
each listed party.

                            Ownership of Common Stock

<TABLE>
<CAPTION>
                                                         Percentage of           Percentage of
Name and Address of              Amount of Beneficial     Common Stock            Total Voting
Beneficial Owner (1)                Ownership (2)         Outstanding           Stock Outstanding
--------------------                -------------         -----------           -----------------
<S>                                 <C>                     <C>                       <C>
Beneficial Holders

Judson Cooper                       1,152,117(3)             8.5%                      8.2%

Howard Gittis
35 East 62nd Street
New York, NY 10021                  1,005,902(4)             7.6%                      7.4%

Panetta Partners, Ltd.(5)
265 E. 66th St. Suite 16G
New York, NY 10021                    790,472(6)             5.8%                      5.7%

Joshua D. Schein                    1,178,517(3)             8.7%                      8.4%

Officers and Directors

Thomas N. Konatich                    395,000(7)             3.0%                      2.9%

Dennis E. Hruby                       475,000(7)             3.6%                      3.5%

Donald G. Drapkin
35 East 62nd Street
New York, NY 10021                  2,855,058(8)(9)(10)     19.1%                     18.6%

Gabriel M. Cerrone(5)
265E. 66th Street, Suite 16G
New York, NY 10021                  1,926,972(6)(11)        13.2%                     12.8%

Thomas E. Constance
919 Third Avenue, 41st Floor
New York, NY 10022                    253,467(12)            1.9%                      1.9%

Mehmet C. Oz, M.D
177 Fort Washington Ave
New York, NY 10032                    125,000(13)            1.0%                      0.9%

Eric A. Rose, M.D
122 East 78th Street
New York, NY 10021                    790,090(14)            5.8%                      5.6%

Michael Weiner, M.D
161 Fort Washington Ave
New York, NY 10032                    125,000(13)            1.0%                      0.9%

All Officers and Directors as a
group (eight persons)               6,945,587(15)           37.1%                     36.3%
</TABLE>

----------
*     Less than 1%

(1)   Unless otherwise indicated the address of each beneficial owner identified
      is 420 Lexington Avenue, Suite 601, New York, NY 10170.

(2)   Unless otherwise indicated, each person has sole investment and voting
      power with respect to the shares indicated. For purposes of this table, a
      person or group of persons is deemed to have "beneficial ownership" of any
      shares as of a given date which such person has the right to acquire
      within 60 days after such date. For purposes of computing the percentage
      of outstanding shares held by each person or group of persons named above
      on a given date, any security which such person or persons has the right
      to acquire within 60 days after such


                                     - 36 -
<PAGE>

      date is deemed to be outstanding for the purpose of computing the
      percentage ownership of such person or persons, but is not deemed to be
      outstanding for the purpose of computing the percentage ownership of any
      other person.

(3)   The amounts in the table for each of Mr. Cooper and Dr. Schein includes
      options to purchase 700,001 shares of common stock owned directly and
      beneficial ownership of options to purchase 12,500 shares of common stock,
      held by Prism Ventures LLC, an entity jointly owned by Mr. Cooper and Dr.
      Schein.

(4)   Includes 260,178 shares issuable upon exercise of a warrant.

(5)   Mr. Cerrone, as the sole general partner of Panetta Partners, Ltd., may be
      deemed to beneficially own the shares owned by Panetta Partners, Ltd.

(6)   Includes 649,388 shares issuable upon exercise of warrants.

(7)   Messrs. Konatich and Hruby own no shares of common stock. All shares
      listed as beneficially owned by Messrs. Konatich and Hruby are shares
      issuable upon exercise of stock options.

(8)   Includes 1,125,000 shares of common stock issuable upon exercise of
      options and 30,500 shares issuable upon exercise of warrant.

(9)   Mr. Drapkin has entered into a management restructuring agreement,
      pursuant to which he has been granted proxies giving him voting power over
      an aggregate of 905,632 shares of common stock, included in the figures in
      the above table.

(10)  Mr. Drapkin holds, inter alia, a warrant (an "Investor Warrant") to
      purchase 347,826 shares of common stock. However, the Investor Warrant
      provides that, with certain limited exceptions, it is not exercisable if,
      as a result of such exercise, the number of shares of common stock
      beneficially owned by Mr. Drapkin and his affiliates (other than shares of
      common stock which may be deemed beneficially owned through the ownership
      of the unexercised portion of such Investor Warrant) would exceed 9.99% of
      the outstanding shares of common stock. As a result of the restrictions
      described in the immediately preceding sentence and the other securities
      which Mr. Drapkin may be deemed beneficially to own, Mr. Drapkin's
      Investor Warrant is not presently exercisable. If not for the 9.99% limit,
      Mr. Drapkin could be deemed to beneficially own 3,202,884 shares of common
      stock, or 19.9% of the outstanding shares of common stock and 19.4% of the
      total shares of voting stock outstanding.

(11)  Includes 790,472 shares held by and issuable upon exercise of warrants
      held by Panetta Partners and 1,075,000 shares issuable upon exercise of
      options.

(12)  Includes 12,200 shares issuable upon exercise of warrants and 225,000
      shares of common stock issuable upon exercise of options.

(13)  Includes 12,500 shares issuable upon exercise of warrants and 100,000
      shares issuable upon exercise of options.

(14)  Includes 88,610 shares issuable upon exercise of warrants and 600,000
      shares of common stock issuable upon exercise of options.

(15)  See footnotes (5), (6), (7), (8), (9), (10), (11), (12), (13) and (14).

Equity Compensation Plan Information

      The following table sets forth certain equity compensation plan
information with respect to both equity compensation plans approved by security
holders and equity compensation plans not approved by security holders as of
December 31, 2002

<TABLE>
<CAPTION>
                                                                                                        Number of securities
                                             Number of securities to                                remaining available for future
                                                 be issued upon          Weighted-average                      issuance
                                             exercise of outstanding     exercise price of         under equity compensation plans
                                              options, warrants and     outstanding options,            (excluding securities
                                                     rights             warrants and rights            reflected in column (a))
Plan category                                         (a)                      (b)                              (c)
-------------                                -----------------------     -----------------         -------------------------------
<S>                                             <C>                               <C>                       <C>
Equity  compensation  plans approved
  by security holders (1) ..........            5,807,561                         $2.52                     1,480,314

Equity compensation plans not
 approved by security holders ......              250,000                         $2.00                             0

Total ..............................            6,057,561                         $2.50                     1,480,314

</TABLE>

                                     - 37 -
<PAGE>

      (1) SIGA Technologies, Inc., Amended and Restated 1996 Incentive and
          Non-Qualified Stock Option Plan

Item 12. Certain Relationships and Related Transactions

      Thomas E. Constance, a director of SIGA, is Chairman of Kramer Levin
Naftalis & Frankel LLP, a law firm in New York City, which SIGA retained to
provide legal services during fiscal year 2001.

      Donald G. Drapkin, Chairman of the Board of Directors of SIGA, is also a
director with TransTech Pharma, Inc., a company with which we have a
collaborative agreement.





                                     - 38 -
<PAGE>

                                     PART IV

Item 13. Exhibits, Material Agreements and Reports on Form 8-K

3(a)      Restated Articles of Incorporation of the Company (Incorporated by
          reference to Form S-3 Registration Statement of the Company dated May
          10, 2000 (No. 333-36682)).

3(b)      Bylaws of the Company (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

3(c)      Certificate of Designations of Series and Determination of Rights and
          Preferences of Series A Convertible Preferred Stock of the Company
          dated July 2, 2001 (Filed herewith).

4(a)      Form of Common Stock Certificate (Incorporated by reference to Form
          SB-2 Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

4(b)      Warrant Agreement dated as of September 15, 1996 between the Company
          and Vincent A. Fischetti (1) (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

4(c)      Warrant Agreement dated as of November 18, 1996 between the Company
          and David de Weese (1) (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

4(d)      Registration Rights Agreement between the Company and MedImmune, Inc.,
          dated as of February 10, 1998. (Incorporated by reference to the
          Company's Annual Report on Form 10-KSB for the year ended December 31,
          1997).

4(e)      Warrant Agreement between the Company and Stefan Capital, dated
          September 9, 1999 (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 1999).

10(a)     License and Research Support Agreement between the Company and The
          Rockefeller University, dated as of January 31, 1996; and Amendment to
          License and Research Support Agreement between the Company and The
          Rockefeller University, dated as of October 1, 1996(2) (Incorporated
          by reference to Form SB-2 Registration Statement of the Company dated
          March 10, 1997 (No. 333-23037)).

10(b)     Research Agreement between the Company and Emory University, dated as
          of January 31, 1996(2) (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(c)     Research Support Agreement between the Company and Oregon State
          University, dated as of January 31, 1996(2) (Incorporated by reference
          to Form SB-2 Registration Statement of the Company dated March 10,
          1997 (No. 333-23037)). Letter Agreement dated as of March 5, 1999 to
          continue the Research Support Agreement. (Incorporated by reference to
          the Company's Annual Report on Form 10-KSB for the year ended December
          31, 1999).

10(d)     Option Agreement between the Company and Oregon State University,
          dated as of November 30, 1999 and related Amendments to the Agreement
          (Incorporated by reference to the Company's Annual Report on Form
          10-KSB for the year ended December 31, 1999).



                                     - 39 -
<PAGE>

10(e)     Amended and Restated Employment Agreement between the Company and Dr.
          Joshua D. Schein, dated as of October 6, 2000 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2000).

10(f)     Amended and Restated Employment Agreement between the Company and
          Judson A. Cooper, dated as of October 6, 2000 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2000).

10(g)     Employment Agreement between the Company and Dr. Kevin F. Jones, dated
          as of January 1, 1996 (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(h)     Employment Agreement between the Company and David de Weese, dated as
          of November 18, 1996(1) (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(i)     Consulting Agreement between the Company and CSO Ventures LLC, dated
          as of January 1, 1996 (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(j)     Consulting Agreement between the Company and Dr. Vincent A. Fischetti,
          dated as of January 1, 1996 (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(k)     Consulting Agreement between the Company and Dr. Dennis Hruby, dated
          as of January 1, 1996 (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(l)     Letter Agreement between the Company and Dr. Vincent A. Fischetti,
          dated as of March 1, 1996 (Incorporated by reference to Form SB-2
          Registration Statement of the Company dated March 10, 1997 (No.
          333-23037)).

10(m)     Employment Agreement between the Company and Dr. Dennis Hruby, dated
          as of April 1, 1997 (Incorporated by reference to Amendment No. 1 to
          Form SB-2 Registration Statement of the Company dated July 11, 1997
          (No. 333-23037)).

10(n)     Clinical Trials Agreement between the Company and National Institute
          of Allergy and Infectious Diseases, dated as of July 1, 1997
          (Incorporated by reference to Amendment No. 1 to Form SB-2
          Registration Statement of the Company dated July 11, 1997 (No.
          333-23037)).

10(o)     Research Agreement between the Company and The Research Foundation of
          State University of New York, dated as of July 1, 1997(2)
          (Incorporated by reference to Amendment No. 1 to Form SB-2
          Registration Statement of the Company dated July 11, 1997 (No.
          333-23037)).

10(p)     Collaborative Research and License Agreement between the Company and
          Wyeth, dated as of July 1, 1997(2) (Incorporated by reference to
          Amendment No. 3 to Form SB-2 Registration Statement of the Company
          dated September 2, 1997 (No. 333-23037)).

10(q)     Collaborative Evaluation Agreement between the Company and Chiron
          Corporation, dated as of July 1, 1997 (Incorporated by reference to
          Amendment No. 1 to Form SB-2 Registration Statement of the Company
          dated July 11, 1997 (No. 333-23037)).



                                     - 40 -
<PAGE>

10(r)     Consulting Agreement between the Company and Dr. Scott Hultgren, dated
          as of July 9, 1997 (Incorporated by reference to Amendment No. 1 to
          Form SB-2 Registration Statement of the Company dated July 11, 1997
          (No. 333-23037)).

10(s)     Letter of Intent between the Company and MedImmune, Inc., dated as of
          July 10, 1997 (Incorporated by reference to Amendment No. 1 to Form
          SB-2 Registration Statement of the Company dated July 11, 1997 (No.
          333-23037)).

10(t)     Research Collaboration and License Agreement between the Company and
          The Washington University, dated as of February 6, 1998 (2).
          (Incorporated by reference to the Company's Annual Report on Form
          10-KSB for the year ended December 31, 1997).

10(u)     Settlement Agreement and Mutual Release between the Company and The
          Washington University, dated as of February 17, 2000 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 1999).

10(v)     Technology Transfer Agreement between the Company and MedImmune, Inc.,
          dated as of February 10, 1998. (Incorporated by reference to the
          Company's Annual Report on Form 10-KSB for the year ended December 31,
          1997).

10(w)     Employment Agreement between the Company and Dr. Dennis Hruby, dated
          as of January 1, 1998. (Incorporated by reference to the Company's
          Annual Report on Form 10-KSB for the year ended December 31, 1997).
          Amendment to the Agreement, dated as of October 15, 1999 (Incorporated
          by reference to the Company's Annual Report on Form 10-KSB for the
          year ended December 31, 1999). Amendment to the Agreement dated as of
          June 12, 2000).

10(x)     Employment Agreement between the Company and Dr. Walter Flamenbaum,
          dated as of February 1, 1998. (Incorporated by reference to the
          Company's Annual Report on Form 10-KSB for the year ended December 31,
          1997).

10(y)     Employment Agreement between the Company and Thomas Konatich, dated as
          of April 1, 1998. (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 1997). Extension
          and Amendment of the Agreement, dated as of January 19, 2000
          (Incorporated by reference to the Company's Annual Report on Form
          10-KSB for the year ended December 31, 1999). Amendment and
          Restatement of the Agreement, dated as of October 6, 2000
          (Incorporated by reference to the Company's Annual Report on Form
          10-KSB for the year ended December 31, 2000).

10(z)     Consulting Agreement between the Company and Prism Ventures LLC, dated
          as of January 15, 1998. (Incorporated by reference to the Company's
          Annual Report on Form 10-KSB for the year ended December 31, 1997).

10(aa)    Small Business Innovation Research Grant to the Company by the
          National Institutes for Health, dated June 21, 1999 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 1999).

10(bb)    Small Business Innovation Research Grant to the Company by the
          National Institutes for Health, dated September 27, 1999 (Incorporated
          by reference to the Company's Annual Report on Form 10-KSB for the
          year ended December 31, 1999).

10(cc)    Software Application Development Services Agreement between the
          Company and Open-i Media, Inc., dated October 15, 1999 (Incorporated
          by reference to the Company's Annual Report on Form 10-KSB for the
          year ended December 31, 1999).



                                     - 41 -
<PAGE>

10(dd)    Media Development Agreement Services Agreement between the Company and
          Open-i Media, Inc., dated March 15, 2000 (Incorporated by reference to
          the Company's Annual Report on Form 10-KSB for the year ended December
          31, 1999).

10(ee)    Option Agreement between the Company and Ross Products Division of
          Abbott Laboratories, dated February 28, 2000 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 1999).

10(ff)    Consulting Agreement between the Company and Stefan Capital, dated
          September 9, 1999 (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 1999).

10(gg)    Stock Purchase Agreement between the Company and MedImmune, Inc.,
          dated as of February 10, 1998. (Incorporated by reference to the
          Company's Annual Report on Form 10-KSB for the year ended December 31,
          1997).

10(hh)    Small Business Innovation Research Grant to the Company by the
          National Institutes for Health, dated May 3, 2000. (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2000).

10(ii)    Small Business Innovation Research Grant to the Company by the
          National Institutes for Health, dated August 1, 2000. (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2000).

10(jj)    Small Business Innovation Research Grant to the Company by the
          National Institutes for Health, dated August 21, 2000. (Incorporated
          by reference to the Company's Annual Report on Form 10-KSB for the
          year ended December 31, 2000).

10(kk)    Stock Purchase Agreement between the Company and Open-i Media, Inc.
          dated July 7, 2000. (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 2000).

10(ll)    Agreement between the Company and Oregon State University for the
          Company to provide contract research services to the University dated
          September 24, 2000. (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 2000).

10(mm)    Agreement between the Company and Maxygen, Inc. dated October 17,
          2000. (Incorporated by reference to the Company's Annual Report on
          Form 10-KSB for the year ended December 31, 2000).

10(nn)    License and Research Agreements between the Company and the Regents of
          the University of California dated December 6, 2000. (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2000).

10(oo)    Research Agreement between the Company and the University of Maryland
          dated January 3, 2001) (Incorporated by reference to the Company's
          Annual Report on Form 10-KSB for the year ended December 31, 2000).

10(pp)    Amended and Restated 1996 Incentive and Non-Qualified Stock Option
          Plan dated August 15, 2001 (Incorporated by reference to the Company's
          Annual Report on Form 10-KSB for the year ended December 31, 2001).

10(qq)    Letter Agreement among the Company, Donald G. Drapkin, Gabriel
          Cerrone, Thomas E. Constance, Eric A. Rose, Judson A. Cooper and
          Joshua D. Schein dated March 30, 2001 (Incorporated by reference to
          the Company's Annual Report on Form 10-KSB for the year ended December
          31, 2001).



                                     - 42 -
<PAGE>

10(rr)    Separation Agreement between the Company and Joshua D. Schein dated as
          of March 30, 2001 (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 2001).

10(ss)    Separation Agreement between the Company and Judson A. Cooper dated as
          of March 30, 2001 (Incorporated by reference to the Company's Annual
          Report on Form 10-KSB for the year ended December 31, 2001).

10(tt)    Employment Agreement between the Company and Philip Sussman dated June
          22, 2001 (Incorporated by reference to the Company's Annual Report on
          Form 10-KSB for the year ended December 31, 2001).

10(uu)    Amendment to Employment Agreement between the Company and Dr. Dennis
          Hruby dated as of January 31, 2002 (Incorporated by reference to the
          Company's Annual Report on Form 10-KSB for the year ended December 31,
          2001).

10(vv)    Amendment and Waiver to Employment Agreement between the Company and
          Thomas Konatich dated as of January 31, 2002 (Incorporated by
          reference to the Company's Annual Report on Form 10-KSB for the year
          ended December 31, 2001).

10(ww)    Small Business Innovation Grant to the Company from the National
          Institutes of Health dated May 17, 2002 (filed herewith).

10(xx)    Research and License Agreement between the Company and TransTech
          Pharma, Inc. dated October 1, 2002 (filed herewith).

10(yy)    Amendment to Employment Agreement between the Company and Denis Hruby
          dated October 1, 2002 (filed herewith).

10(zz)    Retainer Agreement between the Company and Saggi Captial, Inc.,
          dated November 1, 2002 (filed herewith).

10(aaa)   Retainer Agreement between the Company and Bridge Ventures, Inc.,
          dated November 1, 2002 (filed herewith).

10(bbb)   Amendment to Employment Agreement between the Company and Thomas N.
          Konatich, dated November 5, 2002 (filed herewith).

10(ccc)   Contract between the Company and the Department of the US Army dated
          December 12, 2002 (filed herewith).

10(ddd)   Contract between the Company and Four Star Group dated February 5,
          2003 (filed herewith).

23.1      Consent of Independent Accountants.

99.1      Certification pursuant to U.S.C. Section 1350, as adopted pursuant to
          Section 906 of the Sarbanes-Oxley Act of 2002.

----------
(1)   These agreements were entered into prior to the reverse split of the
      Company's Common Stock and, therefore, do not reflect such reverse split.

(2)   Confidential information is omitted and identified by an * and filed
      separately with the SEC with a request for Confidential Treatment.(b)

      Reports on Form 8-K

      On October 10, 2002, we filed with the SEC a report on Form 8-K stating
      that, on October 4, 2002, we raised approximately $930,000 through a
      private placement of our common stock.


                                     - 43 -
<PAGE>

Item 14 Controls and Procedures

      Within 90 days prior to the filing date of this Annual Report on Form
10-K, the Company's management, including the Acting Chief Executive Officer,
Chief Financial Officer, carried out an evaluation of the effectiveness of the
Company's disclosure controls and procedures as defined in Exchange Act Rule
13a-14. Based upon that evaluation, the Acting Chief Executive Officer and Chief
Financial Officer has concluded that the Company's current disclosure controls
and procedures are effective. There have been no significant changes in the
Company's internal controls or in other factors that could significantly affect
internal controls subsequent to the date of the evaluation by the Acting Chief
Executive Officer and Chief Financial Officer.

      The design of any system of controls and procedures is based in part upon
certain assumptions about the likelihood of future events. There can be no
assurance that any design will succeed in achieving its stated goals under all
potential future conditions, regardless of how remote.

Item 15 Principal Accountant Fees and Services

Current Year
Audit Fees

      PricewaterhouseCoopers LLP billed SIGA $101,580 in the aggregate, for
professional services rendered by them for the audit of SIGA's annual financial
statements for the fiscal year ended December 31, 2002, and the reviews of the
interim financial statements included in SIGA's form 10-QSB filed during the
year ended December 31, 2002.

Audit Related Fees

      PricewaterhouseCoopers LLP billed SIGA $255,690 in the aggregate for
assurance and related services primarily with regard to the acquisition of
Allergy Therapeutics Holdings Ltd. rendered by them during the fiscal year ended
December 31, 2002.

Prior Year Proxy
Audit Fees

      PricewaterhouseCoopers LLP billed SIGA $105,000 in the aggregate, for
professional services rendered by them for the audit of SIGA's annual financial
statements for the fiscal year ended December 31, 2001, and the reviews of the
interim financial statements included in SIGA's form 10-QSB filed during the
year ended December 31, 2001.

All Other Fees

      PricewaterhouseCoopers LLP billed SIGA $30,870 in the aggregate, for all
other services rendered by them (other than those covered above under "Audit
Fees") during the fiscal year ended December 31, 2001.




                                     - 44 -
<PAGE>

SIGNATURES

      Pursuant to the requirements of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized.

                                          SIGA TECHNOLOGIES, INC.
                                          (Registrant)

Date: March 31, 2003                      By:   /s/ Thomas N. Konatich
                                                ------------------------------
                                                Thomas N. Konatich
                                                Chief Financial Officer & Acting
                                                Chief Executive Officer

      Pursuant to the requirements of the Securities Act of 1934, this report
has been signed below by the following persons on behalf of the registrant and
in the capacities and on the dates indicated.

<TABLE>
<CAPTION>
Signature                                  Capacity                                   Date
---------                                  --------                                   ----
<S>                                        <C>                                    <C>
/s/ Donald G. Drapkin                      Chairman of the Board                  March 31, 2003
-------------------------------------
Donald G. Drapkin

/s/ Thomas N. Konatich                     Acting Chief Executive Officer,        March 31, 2003
-------------------------------------      Chief Financial Officer and Secretary
Thomas N. Konatich

/s/ Gabriel M. Cerrone                     Director                               March 31, 2003
-------------------------------------
Gabriel M. Cerrone

/s/ Thomas E. Constance                    Director                               March 31, 2003
-------------------------------------
Thomas E. Constance

/s/ Mehmet C. Oz, M.D.                     Director                               March 31, 2003
-------------------------------------
Mehmet C. Oz, M.D.

/s/ Eric A. Rose                           Director                               March 31, 2003
-------------------------------------
Eric A. Rose, M.D.

/s/ Michael Weiner                         Director                               March 31, 2003
-------------------------------------
Michael Weiner, M.D.
</TABLE>



                                     - 45 -
<PAGE>

                                  CERTIFICATION

I, Thomas N. Konatich, certify that:

      1.    I have reviewed this annual report on Form 10-KSB of SIGA
            Technologies, Inc.;

      2.    Based on my knowledge, this annual report does not contain any
            untrue statement of a material fact or omit to state a material fact
            necessary to make the statements made, in light of the circumstances
            under which such statements were made, not misleading with respect
            to the period covered by this annual report;

      3.    Based on my knowledge, the financial statements and other financial
            information included in this annual report, fairly present in all
            material respects the financial condition, results of operations and
            cash flows of the registrant as of, and for, the periods presented
            in this annual report;

      4.    I am responsible for establishing and maintaining disclosure
            controls and procedures (as defined in Exchange Act Rules 13a-14 and
            15d-14) for the registrant and I have:

            a)    designed such disclosure controls and procedures to ensure
                  that material information relating to the registrant,
                  including its consolidated subsidiaries, is made known to us
                  by others within those entities, particularly during the
                  period in which this annual report is being prepared;

            b)    evaluated the effectiveness of the registrant's disclosure
                  controls and procedures as of a date within 90 days prior to
                  the filing date of this annual report (the "Evaluation
                  Date"); and

            c)    presented in this annual report our conclusions about the
                  effectiveness of the disclosure controls and procedures based
                  on our evaluation as of the Evaluation Date;

      5.    I have disclosed, based on my most recent evaluation, to the
            registrant's auditors and the audit committee of registrant's board
            of directors (or persons performing the equivalent function):

            a)    all significant deficiencies in the design or operation of
                  internal controls which could adversely affect the
                  registrant's ability to record, process, summarize and report
                  financial data and have identified for the registrant's
                  auditors any material weaknesses in internal controls; and

            b)    any fraud, whether or not material, that involves management
                  or other employees who have a significant role in the
                  registrant's internal controls; and

      6.    I have indicated in this annual report whether or not there were
            significant changes in internal controls or in other factors that
            could significantly affect internal controls subsequent to the date
            of our most recent evaluation, including any corrective actions with
            regard to significant deficiencies and material weaknesses.


                               /s/ Thomas N. Konatich
                               -------------------------------
                               Thomas N. Konatich
                               Acting Chief Executive Officer
                               and Chief Financial Officer
                               March 31, 2003

<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Financial Statements
December 31, 2002 and 2001




<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Index to Financial Statements
--------------------------------------------------------------------------------

Report of Independent Accountants                                           F-2

Balance Sheets as of December 31, 2002 and 2001                             F-3

Statement of Operations for the years ended December 31, 2002 and
   2001, and for the period from inception through December 31, 2002        F-4

Statement of Changes in Stockholders' Equity for the period
   from inception through December 31, 2002                                 F-5

Statement of Cash Flows for the years ended December 31, 2002 and
   2001, and for the period from inception through December 31, 2002        F-8

Notes to Financial Statements                                               F-9



                                      F-1
<PAGE>

                        Report of Independent Accountants


To the Board of Directors and Stockholders
of SIGA Technologies, Inc.

In our opinion, the accompanying balance sheets and related statements of
operations, of cash flows and of changes in stockholders' equity (deficit)
present fairly, in all material respects, the financial position of SIGA
Technologies, Inc. (a development stage company) at December 31, 2002 and 2001,
and the results of its operations and cash flows for the years ended December
31, 2002 and 2001, and for the period from December 28, 1995 ("Inception")
through December 31, 2002, in conformity with accounting principles generally
accepted in the United States of America. These financial statements are the
responsibility of the Company's management; our responsibility is to express an
opinion on these financial statements based on our audits. We conducted our
audits of these statements in accordance with auditing standards generally
accepted in the United States of America which require that we plan and perform
the audit to obtain reasonable assurance about whether the financial statements
are free of material misstatement. An audit includes examining, on a test basis,
evidence supporting the amounts and disclosures in the financial statements,
assessing the accounting principles used and significant estimates made by
management, and evaluating the overall financial statement presentation. We
believe that our audits provide a reasonable basis for our opinion.


\s\PricewaterhouseCoopers LLP
-----------------------------

New York, New York
February 14, 2003



                                      F-2
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Balance Sheets
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                                         December 31,
                                                                                   2002            2001
                                                                                ------------    ------------
<S>                                                                             <C>             <C>
Assets

Current Assets:
    Cash and cash equivalents                                                   $  2,069,004    $  3,148,160
    Accounts receivable                                                               60,151          55,000
    Prepaid expenses                                                                 104,227         153,416
                                                                                ------------    ------------
               Total current assets                                                2,233,382       3,356,576

    Equipment, net                                                                   432,442         703,239
    Other assets                                                                     164,168         147,873
                                                                                ------------    ------------

               Total assets                                                     $  2,829,992    $  4,207,688
                                                                                ============    ============

Liabilities and Stockholders' Equity:

Current liabilities:
    Accounts payable                                                            $    461,146    $    210,391
    Accrued expenses and other                                                       184,554         263,616
    Capital lease obligations                                                         11,206         192,196
                                                                                ------------    ------------
               Total liabilities                                                     656,906         666,203

Commitments and contingencies

Stockholders' equity:
    Series A convertible preferred stock ($.0001 par value, 10,000,000 shares
       authorized, 410,760 and 379,294 issued and outstanding at
       December 31, 2002 and 2001, respectively)                                     443,674         398,441
    Common stock ($.0001 par value, 50,000,000 shares authorized,
        12,902,053 and 10,139,553 issued and outstanding at December 31,
       2002 and 2001, respectively)                                                    1,293           1,016
    Additional paid-in capital                                                    32,051,461      29,348,786
    Stock subscriptions outstanding                                                 (791,940)             --
    Deferred compensation                                                                 --         (35,583)
    Deficit accumulated during the development stage                             (29,531,402)    (26,171,175)
                                                                                ------------    ------------

               Total stockholders' equity                                          2,173,086       3,541,485
                                                                                ------------    ------------

               Total liabilities and stockholders' equity                       $  2,829,992    $  4,207,688
                                                                                ============    ============
</TABLE>


   The accompanying notes are an integral part of these financial statements.


                                      F-3
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Statement of Operations
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                                             For the Period
                                                                                              December 28,
                                                                                             1995 (Date of
                                                                 Year Ended December 31,     Inception) to
                                                              ----------------------------    December 31,
                                                                  2002             2001          2002
<S>                                                           <C>             <C>             <C>
 Revenues:
     Research and development contracts                       $    344,450    $  1,159,500    $  3,631,631
                                                              ------------    ------------    ------------

 Operating expenses:
     General and administrative                                  1,838,470       2,570,869      17,221,915
     Research and development (including amounts to
        related parties of $59,000, $104,000, and $547,581
        for the years ended December 31, 2002 and
        2001, and for the period from the date of inception      1,766,368       1,733,188      13,775,444
        to December 31, 2002)
     Patent preparation fees                                       104,700         117,264       1,459,454
                                                              ------------    ------------    ------------

               Total operating expenses                          3,709,538       4,421,321      32,456,813
                                                              ------------    ------------    ------------

               Operating loss                                   (3,365,088)     (3,261,821)    (28,825,182)

 Interest income/(expense)                                          34,061        (192,679)       (312,983)
 Loss on impairment of investment                                       --        (275,106)       (430,697)
 Other income/gain on sale of securities                                --              --          66,660
                                                              ------------    ------------    ------------

               Net loss                                         (3,331,027)     (3,729,606)    (29,502,202)

 Deemed dividend related to beneficial conversion feature           29,200              --          29,200
                                                              ------------    ------------    ------------

               Net loss applicable to common shareholders     $ (3,360,227)             --    $(29,531,402)
                                                              ============    ============    ============

 Basic and diluted loss per share                             $       (.32)   $       (.44)
                                                              ------------    ------------

Weighted average common shares outstanding
    used for basic and diluted loss per share                   10,450,529       8,499,961
                                                              ============    ============

Comprehensive loss:
    Net loss                                                  $ (3,331,027)   $ (3,729,606)   $(29,502,202)
                                                              ------------    ------------    ------------

               Total comprehensive loss                       $ (3,331,027)   $ (3,729,606)   $(29,502,202)
                                                              ============    ============    ============
</TABLE>


   The accompanying notes are an integral part of these financial statements.


                                      F-4
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Statement of Changes in Stockholders' Equity (Deficit)
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                            Series A
                                                                           Convertible
                                                                         Preferred Stock           Common Stock          Additional
                                                                     ------------------------  -----------------------    Paid-in
                                                                       Shares       Amount       Shares       Amount      Capital
                                                                     -----------  -----------  -----------   ---------   -----------
<S>                                                                           <C> <C>          <C>              <C>      <C>
Issuance of common stock at inception                                             $            $ 2,079,170      $  208   $     1,040
Net loss                                                                                                --          --            --
                                                                     -----------  -----------  -----------   ---------   -----------
             Balances at December 31, 1995                                    --                 2,079,170         208         1,040

Net proceeds from issuance and sale of common stock ($1.50 per share)                            1,038,008         104     1,551,333
Net proceeds from issuance and sale of common stock ($3.00 per share)                              250,004          25       748,985
Receipt of stock subscriptions outstanding                                                              --          --            --
Issuance of compensatory options and warrants                                                           --          --       367,461
Net loss                                                                                                --          --            --
                                                                     -----------  -----------  -----------   ---------   -----------
             Balances at December 31, 1996                                    --                 3,367,182         337     2,668,819

Net proceeds from issuance and sale of common stock ($5.00 per share)                            2,875,000         287    12,179,322
Issuance of warrants with bridge notes                                                                  --          --       133,000
Stock option and warrant compensation                                                                   --          --        68,582
Net loss                                                                                                --          --            --
                                                                     -----------  -----------  -----------   ---------   -----------
             Balance at December 31, 1997                                     --                 6,242,182         624    15,049,723

Issuance of common stock to acquire third party's
    right to certain technology ($4.34 per share)                                                  335,530          34     1,457,424
Issuance of compensatory options and warrants                                                           --          --       175,870
Stock option and warrant compensation                                                                   --          --        14,407
Unrealized losses on available for sale securities                                                      --          --            --
Net loss                                                                                                --          --            --
                                                                     -----------  -----------  -----------   ---------   -----------
             Balance at December 31, 1998                                     --                 6,577,712         658    16,697,424

Issuance of common stock for software development ($1.25 per share)                                 25,000           3        31,247
Issuance of compensatory common stock, options and warrants                                             --                    51,550
Stock option and warrant compensation                                                                   --                    75,278
Unrealized gains on available for sale securities
Net loss
                                                                     -----------  -----------  -----------   ---------   -----------
             Balance at December 31, 1999                                     --                 6,602,712         661    16,855,499
                                                                     -----------  -----------  -----------   ---------   -----------
<CAPTION>

                                                                                                           Deficit
                                                                                                         Accumulated
                                                                                            Stock        During the
                                                                           Deferred     Subscriptions    Development
                                                                         Compensation    Outstanding        Stage
                                                                         -------------   ------------   -------------
<S>                                                                                 <C>   <C>           <C>
Issuance of common stock at inception                                                     $   (1,248)
Net loss                                                                            --            --    $      (1,000)
                                                                         -------------   ------------   -------------
             Balances at December 31, 1995                                          --        (1,248)          (1,000)

Net proceeds from issuance and sale of common stock ($1.50 per share)                             --               --
Net proceeds from issuance and sale of common stock ($3.00 per share)                             --
Receipt of stock subscriptions outstanding                                                     1,248               --
Issuance of compensatory options and warrants                                                     --               --
Net loss                                                                            --            --       (2,268,176)
                                                                         -------------   ------------   -------------
             Balances at December 31, 1996                                          --            --       (2,269,176)

Net proceeds from issuance and sale of common stock ($5.00 per share)
Issuance of warrants with bridge notes                                                            --               --
Stock option and warrant compensation                                                             --               --
Net loss                                                                            --            --       (2,194,638)
                                                                         -------------   ------------   -------------
             Balance at December 31, 1997                                           --            --       (4,463,814)

Issuance of common stock to acquire third party's
    right to certain technology ($4.34 per share)
Issuance of compensatory options and warrants                                                     --               --
Stock option and warrant compensation                                                             --               --
Unrealized losses on available for sale securities                                                --               --
Net loss                                                                            --            --       (6,551,666)
                                                                         -------------   ------------   -------------
             Balance at December 31, 1998                                           --            --      (11,015,480)

Issuance of common stock for software development ($1.25 per share)
Issuance of compensatory common stock, options and warrants
Stock option and warrant compensation
Unrealized gains on available for sale securities
Net loss                                                                                                   (3,636,500)
                                                                         -------------   ------------   -------------
             Balance at December 31, 1999                                           --            --      (14,651,980)
                                                                         -------------   ------------   -------------
<CAPTION>
                                                                          Unrealized
                                                                        Gains (Losses)       Total
                                                                         on Available    Stockholders'
                                                                          for Sale of        Equity
                                                                          Securities       (Deficit)
                                                                        --------------   ------------
<S>                                                                            <C>        <C>
Issuance of common stock at inception                                               --             --
Net loss                                                                            --    $     (1,000)
                                                                         -------------    ------------
             Balances at December 31, 1995                                          --          (1,000)

Net proceeds from issuance and sale of common stock ($1.50 per share)               --       1,551,437
Net proceeds from issuance and sale of common stock ($3.00 per share)               --         749,010
Receipt of stock subscriptions outstanding                                          --           1,248
Issuance of compensatory options and warrants                                       --         367,461
Net loss                                                                            --      (2,268,176)
                                                                         -------------    ------------
             Balances at December 31, 1996                                          --         399,980

Net proceeds from issuance and sale of common stock ($5.00 per share)                       12,179,609
Issuance of warrants with bridge notes                                              --         133,000
Stock option and warrant compensation                                               --          68,582
Net loss                                                                            --      (2,194,638)
                                                                         -------------    ------------
             Balance at December 31, 1997                                           --      10,586,533

Issuance of common stock to acquire third party's
    right to certain technology ($4.34 per share)                                            1,457,458
Issuance of compensatory options and warrants                                       --         175,870
Stock option and warrant compensation                                               --          14,407
Unrealized losses on available for sale securities                             (34,816)        (34,816)
Net loss                                                                            --      (6,551,666)
                                                                         -------------    ------------
             Balance at December 31, 1998                                      (34,816)      5,647,786

Issuance of common stock for software development ($1.25 per share)                             31,250
Issuance of compensatory common stock, options and warrants                                     51,550
Stock option and warrant compensation                                                           75,278
Unrealized gains on available for sale securities                               34,816          34,816
Net loss                                                                                    (3,636,500)
                                                                         -------------    ------------
             Balance at December 31, 1999                                           --       2,204,180
                                                                         -------------    ------------
</TABLE>

                                   (Continued)


                                      F-5
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Statement of Changes in Stockholders' Equity (Deficit)
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                           Series A
                                                                          Convertible
                                                                        Preferred Stock           Common Stock          Additional
                                                                    ------------------------  -----------------------    Paid-in
                                                                      Shares       Amount       Shares       Amount      Capital
                                                                    -----------  -----------  -----------   ---------   -----------
<S>                                                                   <C>        <C>          <C>              <C>      <C>
Net proceeds from exercising of stock options                                    $                 19,875      $    2   $    52,772
Net proceeds from the issuance of common stock ($5.0 per share)                                   600,000          60     2,882,940
Issuance of common stock in connection with software development                                  102,721          10       500,334
Issuance of common shares in connection with acquisition of 12.5%
    equity interest in a private company                                                           40,336           4       179,996
Issuance of common shares upon conversion of debentures                                            90,193           9        49,246
Warrants granted in connection with the issuance of debentures                                                            1,320,170
Issuance of compensatory options and warrants to non-employees                                                            1,218,145
Issuance of compensatory options to employees                                                                               278,750
Stock options and warrants compensation related to services received
    from non-employees                                                                                                      185,876
Amortization of deferred compensation
Issuance of shares in exchange for services                                                        16,000           1            (1)
Amendment of warrants issued to a non-employee for services                                                                 270,256
Net loss
                                                                    -----------  -----------  -----------   ---------   -----------

             Balance at December 31, 2000                                                       7,471,837         747    23,793,983
                                                                    -----------  -----------  -----------   ---------   -----------

Issuance of preferred stock upon conversion of debentures             1,011,593    1,036,707
Common stock issued upon conversion of preferred series A stock        (632,299)    (638,266)     641,719          64       651,735
Net proceeds from issuance of common stock ($2.00 to $3.00 per share                            1,684,636         169     4,356,801
Issuance of common shares upon conversion of stock options                                        167,250          17       196,846
Issuance of common shares upon exercising of warrants                                              70,000           7       159,613
Issuance of restricted common stock to non-employee                                                50,000           5        77,328
Issuance of common shares upon cashless warrant exercise                                           35,640           4            (4)
Issuance of common stock upon conversion of debentures                                             18,471           3        15,916
Issuance of compensatory stock options to the board of directors                                                            612,750
Cancellation of warrants issued to consultant                                                                              (783,598)
Compensation charge relating to common stock issued below
    fair value market                                                                                                       103,040
Compensation charge relating to modification of options to acquire
    common shares                                                                                                            72,660
Amortization of deferred compensation
Stock options issued to non-employee                                                                                         79,054
Warrants issued to a non-employee                                                                                            28,318
Forfeiture of options issued to a director                                                                                  (15,656)

Net loss
                                                                    -----------  -----------  -----------   ---------   -----------

             Balance at December 31, 2001                               379,294      398,441   10,139,553       1,016    29,348,786

<CAPTION>
                                                                                                           Deficit
                                                                                                         Accumulated
                                                                                            Stock        During the
                                                                           Deferred     Subscriptions    Development
                                                                         Compensation    Outstanding        Stage
                                                                         -------------   ------------   -------------
<S>                                                                      <C>                      <C>   <C>
Net proceeds from exercising of stock options
Net proceeds from the issuance of common stock ($5.0 per share)
Issuance of common stock in connection with software development
Issuance of common shares in connection with acquisition of 12.5%
    equity interest in a private company
Issuance of common shares upon conversion of debentures
Warrants granted in connection with the issuance of debentures
Issuance of compensatory options and warrants to non-employees           $  (1,218,145)
Issuance of compensatory options to employees                                 (278,750)
Stock options and warrants compensation related to services received
    from non-employees
Amortization of deferred compensation                                        1,068,470
Issuance of shares in exchange for services
Amendment of warrants issued to a non-employee for services
Net loss                                                                                                $  (7,789,589)
                                                                         -------------   ------------   -------------

             Balance at December 31, 2000                                     (428,425)            --     (22,441,569)
                                                                         -------------   ------------   -------------

Issuance of preferred stock upon conversion of debentures
Common stock issued upon conversion of preferred series A stock
Net proceeds from issuance of common stock ($2.00 to $3.00 per share
Issuance of common shares upon conversion of stock options
Issuance of common shares upon exercising of warrants
Issuance of restricted common stock to non-employee
Issuance of common shares upon cashless warrant exercise
Issuance of common stock upon conversion of debentures
Issuance of compensatory stock options to the board of directors
Cancellation of warrants issued to consultant                                  248,713
Compensation charge relating to common stock issued below
    fair value market
Compensation charge relating to modification of options to acquire
    common shares
Amortization of deferred compensation                                          121,389
Stock options issued to non-employee
Warrants issued to a non-employee                                                7,084
Forfeiture of options issued to a director                                      15,656

Net loss                                                                                                   (3,729,606)
                                                                         -------------   ------------   -------------

             Balance at December 31, 2001                                      (35,583)            --     (26,171,175)

<CAPTION>
                                                                          Unrealized
                                                                        Gains (Losses)       Total
                                                                         on Available    Stockholders'
                                                                          for Sale of        Equity
                                                                          Securities       (Deficit)
                                                                        --------------    ------------
<S>                                                                                <C>    <C>
Net proceeds from exercising of stock options                                             $     52,774
Net proceeds from the issuance of common stock ($5.0 per share)                              2,883,000
Issuance of common stock in connection with software development                               500,344
Issuance of common shares in connection with acquisition of 12.5%                                   --
    equity interest in a private company                                                       180,000
Issuance of common shares upon conversion of debentures                                         49,255
Warrants granted in connection with the issuance of debentures                               1,320,170
Issuance of compensatory options and warrants to non-employees                                      --
Issuance of compensatory options to employees                                                       --
Stock options and warrants compensation related to services received
    from non-employees                                                                         185,876
Amortization of deferred compensation                                                        1,068,470
Issuance of shares in exchange for services                                                         --
Amendment of warrants issued to a non-employee for services                                    270,256
Net loss                                                                                    (7,789,589)


             Balance at December 31, 2000                                           --         924,736


Issuance of preferred stock upon conversion of debentures                                    1,036,707
Common stock issued upon conversion of preferred series A stock                                 13,533
Net proceeds from issuance of common stock ($2.00 to $3.00 per share                         4,356,970
Issuance of common shares upon conversion of stock options                                     196,863
Issuance of common shares upon exercising of warrants                                          159,620
Issuance of restricted common stock to non-employee                                             77,333
Issuance of common shares upon cashless warrant exercise                                            --
Issuance of common stock upon conversion of debentures                                          15,919
Issuance of compensatory stock options to the board of directors                               612,750
Cancellation of warrants issued to consultant                                                 (534,885)
Compensation charge relating to common stock issued below
    fair value market                                                                          103,040
Compensation charge relating to modification of options to acquire
    common shares                                                                               72,660
Amortization of deferred compensation                                                          121,389
Stock options issued to non-employee                                                            79,054
Warrants issued to a non-employee                                                               35,402
Forfeiture of options issued to a director                                                          --

Net loss                                                                                    (3,729,606)

                                                                                                    --
                                                                         -------------    ------------
             Balance at December 31, 2001                                           --       3,541,485
</TABLE>

                                   (Continued)


                                       F-6
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Statement of Changes in Stockholders' Equity (Deficit)
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                           Series A
                                                                          Convertible
                                                                        Preferred Stock           Common Stock          Additional
                                                                    ------------------------  -----------------------    Paid-in
                                                                      Shares       Amount       Shares       Amount      Capital
                                                                    -----------  -----------  -----------   ---------   -----------
<S>                                                                     <C>        <C>         <C>           <C>        <C>
Net proceeds from issuance of common stock
   ($1.00 to $1.09 per share)                                                                   2,737,500         274     2,559,924
Issuance of common shares upon exercise of stock options                                           25,000           3       28,093
Issuance of preferred stock to settle dividends payable                  31,466       45,233
Amortization of deferred compensation
Stock options issued to non-employee                                                                                         85,458
Deemed dividend related to beneficial conversion feature                                                                     29,200

Net loss
                                                                    -----------  -----------  -----------   ---------   -----------

             Balance at December 31, 2002                               410,760    $ 443,674   12,902,053    $  1,293   $32,051,461
                                                                    ===========  ===========  ===========   =========   ===========

<CAPTION>
                                                                                                           Deficit
                                                                                                         Accumulated
                                                                                            Stock        During the
                                                                           Deferred     Subscriptions    Development
                                                                         Compensation    Outstanding        Stage
                                                                         -------------   ------------   -------------
<S>                                                                       <C>              <C>           <C>
Net proceeds from issuance of common stock
   ($1.00 to $1.09 per share)                                                                (791,940)
Issuance of common shares upon exercise of stock options
Issuance of preferred stock to settle dividends payable
Amortization of deferred compensation                                          35,583
Stock options issued to non-employee
Deemed dividend related to beneficial conversion feature                                                      (29,200)

Net loss                                                                                                   (3,331,027)


                                                                         -------------   ------------   -------------
             Balance at December 31, 2002                                 $         --    $  (791,940)  $ (29,531,402)
                                                                         =============   ============   =============

<CAPTION>
                                                                          Unrealized
                                                                        Gains (Losses)       Total
                                                                         on Available    Stockholders'
                                                                          for Sale of        Equity
                                                                          Securities       (Deficit)
                                                                        --------------    ------------
<S>                                                                       <C>             <C>
Net proceeds from issuance of common stock
   ($1.00 to $1.09 per share)                                                                1,768,258
Issuance of common shares upon exercise of stock options                                        28,096
Issuance of preferred stock to settle dividends payable                                         45,233
Amortization of deferred compensation                                                           35,583
Stock options issued to non-employee                                                            85,458
Deemed dividend related to beneficial conversion feature                                            --

Net loss                                                                                    (3,331,027)
                                                                         -------------    ------------
             Balance at December 31, 2002                                 $         --    $  2,173,086
                                                                         =============    ============
</TABLE>

   The accompanying notes are an integral part of these financial statements.


                                      F-7
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Statement of Cash Flows
--------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                                                                              For the Period
                                                                                               December 28,
                                                                         Year Ended           1995 (Date of
                                                              -----------------------------   Inception) to
                                                                December 31,    December 31,   December 31,
                                                                   2002            2001            2002
<S>                                                           <C>             <C>             <C>
Cash flows from operating activities:
  Net loss                                                    $ (3,331,027)   $ (3,729,606)   $(29,502,202)
  Adjustments to reconcile net loss to net
    cash used in operating activities:
       Depreciation                                                317,032         324,463       1,592,381
       Stock, options and warrant compensation                     121,041         566,743       2,996,784
       Loss on impairment of investment                                 --         275,106         430,697
       Loss on write-off of capital equipment                           --              --          97,969
       Amortization of debt discount                                    --         232,393         954,705
       Write-off of in-process research and development                 --              --       1,457,458
       Realized gain on sale of marketable securities                   --              --         (66,660)
       Non-cash research and development                                --              --         500,344
       Changes in assets and liabilities:
         Accounts receivable                                        (5,151)        (17,200)        (60,151)
         Prepaid expenses and other current assets                  49,189        (147,772)       (104,227)
         Other assets                                              (16,295)          8,683        (164,167)
         Accounts payable and accrued expenses                     216,926        (477,649)        704,465
         Accrued interest                                               --          20,390         100,672
                                                              ------------    ------------    ------------

               Net cash used in operating activities            (2,648,285)     (2,944,449)    (21,061,932)
                                                              ------------    ------------    ------------

Cash flows from investing activities:
  Capital expenditures                                             (46,235)             --      (2,203,489)
  Sale (purchase) of investment securities                              --              --          66,660
  Investment in Open-I-Media                                            --              --        (170,000)
                                                              ------------    ------------    ------------

               Net cash flow used in investing activities          (46,235)             --      (2,306,829)
                                                              ------------    ------------    ------------

Cash flows from financing activities:
  Net proceeds from issuance of common stock                     1,768,258       4,356,970      23,488,284
  Receipts of stock subscriptions outstanding                           --              --           1,248
  Gross proceeds from sale of convertible debentures                    --                       1,500,000
  Proceeds from exercise of stock options and
       warrants to acquire common stock                             28,096         356,483         437,353
  Net proceeds from sale of warrants                                    --                          52,174
  Convertible debentures and warrant issuance costs                     --                         (52,500)
  Proceeds from bridge notes                                            --                       1,000,000
  Repayments of bridge notes                                            --                      (1,000,000)
  Proceeds from sale and leaseback of equipment                         --                       1,139,085
  Principal payments on capital lease obligations                 (180,990)       (328,229)     (1,127,879)
                                                              ------------    ------------    ------------

               Net cash provided from financing activities       1,615,364       4,385,224      25,437,765
                                                              ------------    ------------    ------------

Net increase in cash and cash equivalents                       (1,079,156)      1,440,775       2,069,004
Cash and cash equivalents at beginning of period                 3,148,160       1,707,385              --
                                                              ------------    ------------    ------------

Cash and cash equivalents at end of period                    $  2,069,004    $  3,148,160    $  2,069,004
                                                              ============    ============    ============

Supplemental disclosure of non-cash
    investing and financing activities:
       Fixed assets exchanged in acquisition                  $         --    $         --    $     80,697
                                                              ============    ============    ============
       Fair value of common shares exchanged in acquisition   $         --    $         --    $    180,000
                                                              ============    ============    ============
       Notes payable converted into equity                    $         --    $  1,375,000    $  1,500,000
                                                              ============    ============    ============
</TABLE>


   The accompanying notes are an integral part of these financial statements.

                                       F-8


<PAGE>



SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

1.    Organization and Basis of Presentation

      Organization

      SIGA Technologies, Inc. ("SIGA" or the "Company") was incorporated in the
      State of Delaware on December 28, 1995 ("Inception") as SIGA
      Pharmaceuticals, Inc. The Company is engaged in the discovery, development
      and commercialization of vaccines, antibiotics, and novel anti-infectives
      for the prevention and treatment of infectious diseases. The Company's
      technologies are licensed from third parties.

      Basis of presentation

      The Company's activities since inception have consisted primarily of
      sponsoring and performing research and development, performing business
      and financial planning, preparing and filing patent applications and
      raising capital. Accordingly, the Company is considered to be a
      development stage company.

      The accompanying financial statements have been prepared on a basis which
      assumes that the Company will continue as a going concern and which
      contemplates the realization of assets and the satisfaction of liabilities
      and commitments in the normal course of business. Since inception the
      Company has incurred cumulative net losses of $29,502,202 and expects to
      incur additional losses to perform further research and development
      activities. The Company does not have commercial biomedical products and
      management believes that it will need additional funds to complete the
      development of its biomedical products. Management's plans with regard to
      these matters include continued development of its products as well as
      seeking additional research support funds and financial arrangements.
      Although, management continues to pursue these plans, there is no
      assurance that the Company will be successful in obtaining sufficient
      financing on terms acceptable to the Company.

2.    Summary of Significant Accounting Policies

      Cash and cash equivalents

      Cash and cash equivalents consist of short term, highly liquid
      investments, with original maturities of less than three months when
      purchased and are stated at cost. Interest is accrued as earned.

      Equipment

      Equipment is stated at cost. Depreciation is provided on the straight-line
      method over the estimated useful lives of the respective assets, which are
      as follows:

      Laboratory equipment                              5 years
      Leasehold improvements                          Life of lease
      Computer equipment                                3 years
      Furniture and fixtures                            7 years

      Revenue recognition

      The Company applies the guidance provided by Staff Accounting Bulletin No.
      101, Revenue Recognition in Financial Statements ("SAB 101"). Under the
      provisions of SAB 101 the Company recognizes revenue from government
      research grants, contract research and development and progress payments
      as services are performed, provided a contractual



                                      F-9
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      arrangement exists, the contract price is fixed or determinable, and the
      collection of the resulting receivable is probable. In situations where
      the Company receives payment in advance of the performance of services,
      such amounts are deferred and recognized as revenue as the related
      services are performed. Non-refundable fees are recognized as revenue over
      the term of the arrangement or based on the percentage of costs incurs to
      date, estimated costs to complete and total expected contract revenue.
      Milestones, which generally are related to substantial scientific or
      technical achievements are recognized in income when the milestone is
      accomplished.

      Research and development

      Research and development costs are expensed as incurred and include costs
      of third parties who conduct research and development, pursuant to
      development and consulting agreements, on behalf of the Company. Costs
      related to the acquisition of technology rights, for which development
      work is still in process, and that have no alternative future uses, are
      expensed as incurred and considered a component of research and
      development costs.

      Income taxes

      Income taxes are accounted for under the asset and liability method
      prescribed by Statement of Financial Accounting Standards No. 109,
      "Accounting for Income Taxes." Deferred income taxes are recorded for
      temporary differences between financial statement carrying amounts and the
      tax basis of assets and liabilities. Deferred tax assets and liabilities
      reflect the tax rates expected to be in effect for the years in which the
      differences are expected to reverse. A valuation allowance is provided if
      it is more likely than not that some or all of the deferred tax asset will
      not be realized.

      Net loss per common share

      Basic EPS is computed by dividing income (loss) available to common
      stockholders by the weighted-average number of common shares outstanding
      during the period. Diluted EPS gives effect to all dilutive potential
      common shares outstanding during the period. The computation of Diluted
      EPS does not assume conversion, exercise or contingent exercise of
      securities that would have an antidilutive effect operating results.

      At December 31, 2002 and 2001, 410,760 and 379,294 shares, respectively,
      of the Company's Series A convertible preferred stock have been excluded
      from the computation of diluted loss per shares as they are anti-dilutive.
      At December 31, 2002 and 2001, outstanding options to purchase 5,807,561
      and 5,139,811 shares, respectively, of the Company's common stock with
      exercise prices ranging from $1.00 to $5.50 have been excluded from the
      computation of diluted loss per share as they are antidilutive. At
      December 31, 2002 and 2001, outstanding warrants to purchase 4,675,144 and
      4,231,428 shares, respectively, of the Company's common stock, with
      exercise prices ranging from $1.00 to $8.25 have been excluded from the
      computation of diluted loss per share as they are anti-dilutive.

      Accounting estimates

      The preparation of financial statements in conformity with generally
      accepted accounting principles requires management to make estimates and
      assumptions that affect the reported amounts of assets and liabilities and
      the disclosure of contingent assets and liabilities at the date of the
      financial statements and the reported amounts of expenses during the
      reporting period. Significant estimates include the value of options and
      warrants granted by the Company. Actual results could differ from those
      estimates.



                                     F-10
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      Fair value of financial instruments

      The carrying value of cash and cash equivalents, and accounts payable and
      accrued expenses approximates fair value due to the relatively short
      maturity of these instruments.

      Concentration of credit risk

      The Company has cash in bank accounts that exceed the FDIC insured limits.
      The Company has not experienced any losses on its cash accounts. No
      allowance has been provided for potential credit losses because management
      believes that any such losses would be minimal.

      Accounting for stock based compensation

      The Company has adopted Statement of Financial Accounting Standard (FAS)
      No. 123, "Accounting for Stock-Based Compensation" ("FAS 123"). As
      provided for by FAS 123, the Company has elected to continue to account
      for its stock-based compensation programs according to the provisions of
      Accounting Principles Board Opinion No. 25, ("APB 25")"Accounting for
      Stock Issued to Employees." Accordingly, compensation expense has been
      recognized to the extent of employee or director services rendered based
      on the intrinsic value of compensatory options or shares granted under the
      plans. The Company has adopted the disclosure provisions required by FAS
      123.

      Had compensation cost for stock options granted been determined based upon
      the fair value at the grant date for awards, consistent with the
      methodology prescribed under FAS 123, the Company's net loss and net loss
      per share would have been as follows:

<TABLE>
<CAPTION>
                                                              12 Months Ended
                                                                December 31,
                                                           2002            2001
<S>                                                    <C>             <C>
Net loss, as reported                                  ($ 3,360,227)   ($ 3,729,606)
                                                       ============    ============
Add: Stock-based employee compensation expense
recorded under APB No. 25                                    35,583         121,389
Deduct: Total stock-based employee compensation
expense determined under fair value based method for
all awards, net of related tax effects                     (153,882)     (7,163,483)
                                                       ------------    ------------
Pro forma net loss                                     ($ 3,478,526)   ($10,771,700)
                                                       ============    ============
Net loss per share:
     Basic-as reported                                 ($      0.32)   ($      0.44)
                                                       ============    ============
     Basic-pro forma                                   ($      0.33)   ($      1.27)
                                                       ============    ============
</TABLE>

      The fair value of the options granted to employees during 2002 and 2001
      ranged from $0.09 to $2.08 on the date of the respective grant using the
      Black-Scholes option-pricing model. The following weighted-average
      assumptions were used for 2002: no dividend yield, expected volatility of
      100%, risk free interest rates of 2.87%-4.50% and an expected term of 3 to
      5 years.

                                     F-11
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      The following weighted-average assumptions were used for 2001: no dividend
      yield, expected volatility of 100%, risk free interest rates of
      3.85%-4.74%, and an expected term of 3 to 5 years.

      Reclassifications

      Certain prior year amounts have been reclassified to conform to current
      year presentation. The impact of these changes is not material and did not
      affect net loss.

      Recent pronouncements

      In 2002, the Financial Accounting Standards Board ("FASB") issued
      Statement of Financial Accounting Standards (FAS) No. 148 "Accounting for
      Stock-Based Compensation - Transition and Disclosure an amendment of FASB
      Statement No. 123" ("FAS 148"). This Statement amends Statement of
      Financial Accounting Standards No. 123, "Accounting for Stock-Based
      Compensation" ("FAS 123"), to provide alternative methods of transition
      for an entity that voluntarily changes to the fair value based method of
      accounting for stock-based employee compensation. It also amends the
      disclosure provisions of that FAS 123 to require prominent disclosure
      about the effects on reported net income of an entity's accounting policy
      decisions with respect to stock-based employee compensation. Finally, this
      Statement amends APB Opinion No. 28, "Interim Financial Reporting", to
      require disclosure about those effects in interim financial information.
      The Company adopted the disclosure provisions of FAS 148.

      In July 2002, the FASB issued Statement of Financial Accounting Standards
      (FAS) No. 146, "Accounting for Costs Associated with Exit or Disposal
      Activities" ("FAS 146"). FAS 146 addresses the recognition, measurement
      and reporting of costs associated with exit or disposal activities that
      are currently accounted for pursuant to Emerging Issues Task Force Issue
      No. 94-3, Liabilities Recognition for Certain Employee Termination
      Benefits and Other Costs to Exit an Activity. Under FAS 146, such
      liabilities, with the exception of certain one-time termination benefits,
      will be recognized and measured initially at their fair value in the
      period in which the liability is incurred. FAS 146 is effective for fiscal
      years beginning after December 15, 2002.





                                     F-12
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

3.    Equipment

      Equipment consisted of the following at December 31, 2002 and 2001:

      Laboratory equipment                     $   896,862    $   862,005
      Leasehold improvements                       627,849        618,315
      Computer equipment                           155,204        153,360
      Furniture and fixtures                       291,637        291,637
                                               -----------    -----------
                                                 1,971,552      1,925,317

           Less - Accumulated depreciation      (1,539,110)    (1,222,078)
                                               -----------    -----------

      Equipment, net                           $   432,442    $   703,239
                                               ===========    ===========

      Depreciation expense for the years ended December 31, 2002 and 2001 was
      $317,032 and $324,463, respectively.

      At December 31, 2002 and 2001, laboratory equipment, computer equipment
      and furniture included approximately $730,500, $117,000 and $291,600,
      respectively, of equipment acquired under capital leases. Accumulated
      depreciation related to such equipment approximated $684,400, $117,000 and
      $190,829, respectively, at December 31, 2002, and $538,300, $78,000 and
      $149,171, respectively, at December 31, 2001.

4.    Stockholders' Equity

      At December 31, 2002, the Company's authorized share capital consisted of
      60,000,000 shares, of which 50,000,000 are designated common shares and
      10,000,000 are designated preferred shares. The Company's Board of
      Directors is authorized to issue preferred shares in series with rights,
      privileges and qualifications of each series determined by the Board.

      Private Placement Offerings

      2002 Placements

      In December 2002, the Company raised gross proceeds of $1.865 million in a
      private offering of common stock and warrants to purchase the Company's
      common stock. The Company sold 1,700,000 shares of common stock. In
      connection with the offering the Company issued 171,216 warrants to
      purchase shares of the Company's common stock to placement agents. The
      warrants are exercisable at a price of $1.65 and have a term of five
      years. The fair value of the warrants on the date of grant was
      approximately $188,970. The Company received net proceeds of $891,000
      prior to December 31, 2002 and net proceeds of $791,940 after December 31,
      2002. As such, as of December 31, 2002, the Company has recorded a
      subscription receivable of $791,940.

      In October 2002, the Company raised gross proceeds of $1.04 million in a
      private offering of common stock and warrants to purchase the Company's
      common stock. The Company sold 1,037,500 shares of common stock and
      518,750 warrants. The warrants are exercisable at $2.25


                                     F-13
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      and have a term of five years. In connection with the offering the Company
      issued 103,750 warrants to purchase shares of the Company's common stock
      to placement agents. The warrants are exercisable at a price of $1.50 and
      have a term of five years. The fair value of the warrants attributable to
      consultants on the date of grant was approximately $64,670.

      Years 2001 and Prior

      In October 2001, the Company raised gross proceeds of $2.55 million in a
      private offering of common stock and warrants to purchase the Company's
      common stock. The Company sold 850,000 shares of common stock and 425,000
      warrants. The warrants are exercisable at $3.60 and have a term of seven
      years. In connection with the offering the Company issued 100,000 warrants
      to purchase shares of the Company's common stock to consultants. The
      warrants are exercisable at a price of $3.60 and have a term of five
      years. The fair value of the warrants on the date of grant was
      approximately $221,300.

      In August 2001, the Company raised gross proceeds of $1,159,500 in a
      private offering of 409,636 shares of common stock and 307,226 warrants to
      purchase shares of the Company's common stock. The warrants are
      exercisable at $3.55 per share and have a term of seven years.

      In May 2001, the Company raised gross proceeds of $850,000 in a private
      offering of common stock and warrants to purchase shares of the Company's
      common stock. The Company sold 425,000 shares of common stock and 425,000
      warrants. The warrants are exercisable at $2.94 and have a term of seven
      years. The investors consisted of members of the board of directors,
      existing investors and new investors representing 43.4%, 5.9% and 50.8% of
      the investors in the transaction, respectively. The Company recorded a
      charge to earnings in the amount of $103,040 representing the intrinsic
      value of the restricted stock purchased by members of the board of
      directors.

      In March 2000 the Company entered into an agreement to sell 600,000 shares
      of the Company's common stock and 450,000 warrants to acquire shares of
      the Company's common stock (the "March Financing") for gross proceeds of
      $3,000,000. Of the warrants issued, 210,000, 120,000 and 120,000 are
      exercisable at $5.00, $6.38 and $6.90, respectively. The warrants have a
      term of three years and are redeemable at $0.01 each by the Company upon
      meeting certain conditions. Offering expenses of $117,000 were paid in
      April 2000. At December 31, 2002, all 450,000 warrants were outstanding.

      In connection with the March financing, SIGA issued a total of 379,000
      warrants to purchase shares of the Company's common stock to Fahnestock &
      Co. (the"Fahnestock Warrants") in consideration for services related to
      the March financing. The warrants had an exercise price of $5.00 per share
      and are exercisable at any time until March 28, 2005. In November 2000,
      the Company entered into a one year consulting agreement with Fahnestock
      and Co. under which the Company will receive marketing, public relations
      acquisitions and strategic planning service. In exchange for such
      services, the Company canceled the Fahnestock Warrants and reissued them
      to effectuate an amendment to the exercise price to $2.00 per share. In
      connection with such amendment, the Company recorded a charge of
      approximately $270,000 in the year ended December 31, 2000.



                                     F-14
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      In January 2000 the Company completed a private placement of 6%
      convertible debentures at an aggregate principal amount of $1,500,000 and
      1,043,478 warrants to purchase shares of the Company's common stock with a
      purchase price of $0.05 per warrant (the "January Financing"). The Company
      received net proceeds of $1,499,674 from the total $1,552,174 gross
      proceeds raised. The debentures are convertible into common stock at
      $1.4375 per share. Interest at the rate of 6% per annum was payable on the
      principal of each convertible debenture in cash or shares of the Company's
      common stock, at the discretion of the Company upon conversion or at
      maturity. The warrants have a term of five years and are exercisable at
      $3.4059 per share. The Company has the right to require the holder to
      exercise the warrants within five days under the following circumstances:
      (i) a registration statement is effective; and (ii) the closing bid price
      for the Company's common stock, for each of any 15 consecutive trading
      days is at least 200% of the exercise price of such warrants. If the
      holder does not exercise the warrants after notice is given, the
      unexercised warrants will expire. The warrants are exercisable for a
      period of five years.

      In connection with the placement of the debentures and warrants, the
      Company recorded debt discount of approximately $1.0 million. Such amount
      represents the value of the warrants calculated using the Black-Scholes
      valuation model. The discount is amortized over the term of the
      debentures. Additionally, during the years ended December 31, 2001 and
      2000, the Company recorded interest expense of $232,393 and $589,312
      respectively, related to the amortization of such debt discount. In 2001
      and 2000, debentures with a principal amount of $1,375,000 and $108,664,
      respectively, along with accrued interest, were converted into 1,011,593
      and 108,884 shares of the Company's preferred and common stock,
      respectively.

      In connection with the January 2000 financing, the Company issued warrants
      to purchase a total of 275,000 shares of common stock to the placement
      agent and the investors' counsel (or their respective designees). These
      warrants have a term of five years and are exercisable at $1.45 per share.
      In connection with the issuance of such warrants, the Company recorded a
      deferred charge of $280,653, which was amortized over the term of the
      debentures.

      Holders of the Series A Convertible Preferred Stock are entitled to (i)
      cumulative dividends at the annual rate of 6% payable when and if declared
      by the Company's board of directors; (ii) in the event of liquidation of
      the Company, each holder is entitled to receive $1.4375 per share (subject
      to certain adjustment) plus all accrued but unpaid dividends; (iii)
      convert each share of Series A to a number of fully paid and
      non-assessable shares of common stock as calculated by dividing $1.4375 by
      the Series A Conversion Price (shall initially be $1.4375); and (iv) vote
      with the holders of other classes of shares on an as converted basis.

      As of December 31, 2001, all of the debentures were converted into shares
      of the Company's preferred or common stock.

      In November 1999, 16,000 shares of the Company's common stock were issued
      in exchange for professional services. The Company recognized non-cash
      compensation expense of $21,500 for the year ended December 31, 1999 based
      upon the fair value of the stock on the date of grant. The Company issued
      the shares in 2000.

      In September and October 1997, the Company completed an initial public
      offering of 2,875,000 shares of its common stock at an offering price of
      $5.00 per share. The Company realized gross


                                     F-15
<PAGE>


SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      proceeds of $14,375,000 and net proceeds, after deducting underwriting
      discounts and commissions, and other offering expenses payable by the
      Company, of $12,179,609.

      Stock option plan and warrants

      1996 Incentive and Non-Qualified Stock Option Plan

      In January 1996, the Company implemented its 1996 Incentive and
      Non-Qualified Stock Option Plan (the "Plan"). The Plan as amended provided
      for the granting of up to 7,500,000 shares of the Company's common stock
      to employees, consultants and outside directors of the Company. The
      exercise period for options granted under the Plan, except those granted
      to outside directors, is determined by a committee of the Board of
      Directors. Stock options granted to outside directors pursuant to the Plan
      must have an exercise price equal to or in excess of the fair market value
      of the Company's common stock at the date of grant and become exercisable
      over a period of three years with a third of the grant being exercisable
      at the completion of each year of service subsequent to the grant.

      Transactions under the Plan are summarized as follows:

<TABLE>
<CAPTION>
                                                                                       Weighted
                                                                                       Average
                                                                        Number of      Exercise
                                                                          Shares        Price
<S>                                                                     <C>              <C>
      Outstanding at January 1, 2001                                     2,167,061       $2.26
           Granted                                                       3,660,000        2.67
           Forfeited                                                      (500,125)       3.60
           Exercised                                                      (187,125)       1.26
                                                                        ----------       -----
      Outstanding at December 31, 2001                                   5,139,811        2.50
           Granted                                                         777,750        2.66
           Forfeited                                                       (85,000)       3.80
           Exercised                                                       (25,000)       1.13
                                                                        ----------       -----

              Total outstanding at December 31, 2002                     5,807,561       $2.52
                                                                        ==========       =====

        Options available for future grant at December 31, 2002          1,480,314
        Weighted average fair value of options granted during 2002      $     0.71
        Weighted average fair value of options granted during 2001      $     1.84
</TABLE>




                                     F-16
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      The following table summarizes information about options outstanding at
      December 31, 2002:

<TABLE>
<CAPTION>
                                       Weighted                      Number
                     Number             Average        Weighted    Exercisable        Weighted
                  Outstanding          Remaining       Average         at             Average
                    December 31,      Contractual     Exercise     December 31,       Exercise
                      2002            Life (Years)      Price           2002           Price
<S>                    <C>                <C>            <C>           <C>                <C>
$ 1.00                    10,000          6.86           1.00             10,000          1.00
1.13                     300,000          6.81           1.13            300,000          1.13
1.50                     167,084          8.48           1.50             36,528          1.50
2.00 - 2.75            4,842,250          8.12           2.38          4,531,625          2.38
3.94 - 5.50              488,227          5.99           4.55            416,894          4.66
                  --------------                                  --------------

                       5,807,561                                       5,295,047
                  ==============                                  ==============
</TABLE>

      The following tables summarize information about warrants outstanding at
      December 31, 2002:

<TABLE>
<CAPTION>
                                    Number of    Weighted Average   Expiration
                                    Warrants     Exercise Price       Dates
<S>                                 <C>              <C>       <C>
Outstanding at January 1, 2001      3,694,202        $ 4.04
                                                     ------
     Granted                        1,257,226          3.37    05/31/08 - 10/15/08
     Exercised                       (120,000)         1.85
     Canceled / Expired              (600,000)         6.43
                                    ---------        ------
Outstanding at December 31, 2001    4,231,428          3.61
     Granted                          793,716          2.03    09/30/07 - 12/31/07
     Canceled / Expired              (350,000)         7.32
                                    ---------

Outstanding at December 31, 2002    4,675,144         $3.06
                                    ---------        ------
</TABLE>

                       Number
                     of Warrants                         Exercise
                     Outstanding                           Price


                           100,000                         1.00
                           679,966                      1.45 - 1.65
                           877,750                      2.00 - 2.25
                         2,551,212                      2.94 - 3.63
                           226,216                      4.63 - 5.00
                           240,000                      6.38 - 6.90
                   ----------------
                         4,675,144
                   ----------------


                                     F-17
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      2002 Grants

      At December 31, 2002, options granted outside of the plan included 125,000
      options granted to an employee and 125,000 options granted to consultants.

      In September 2002, the Company entered into a four-month consulting
      agreement under which the consultant assists the Company with public
      relations efforts in the United States of America and Europe in exchange
      for a monthly retainer of $3,500 for the four-month term and 50,000 fully
      vested options to purchase shares of the Company's common stock. Of the
      amount of fully vested options, 25,000 shares have an exercise price of
      $1.50 per share and 25,000 shares have an exercise price of $1.75. Upon
      grant, the Company recorded a $31,618 stock compensation charge to
      operations based upon the fair value of the options.

      In April 2002, in connection with an existing consulting agreement, the
      Company granted a consultant an option to purchase 15,000 shares of the
      Company's common stock under the Plan. Upon grant, the Company recorded a
      $10,269 stock compensation charge to operations based upon the fair value
      of the option.

      Years 2001 and Prior

      In June 2001, the Company entered into a one year consulting agreement
      under which the consultant assists the Company with public relations
      efforts in Europe in exchange for 50,000 shares of the Company's
      restricted common stock. The restricted stock vests at an equal rate over
      the period of the agreement. As the restricted stock vests, the Company
      will record charges to earnings based upon the difference between the fair
      value and the price of the restricted stock. During the year ended
      December 31, 2001, the Company has recorded stock compensation charges to
      earnings in the amount of $77,333.

      In May 2001, subject to approval by the shareholders, the Company granted
      3,225,000 options, at an exercise price of $2.50 per share, to the members
      of the new board of directors. Subsequent to the approval by the
      shareholders the Company recorded charges to earnings in the amount of
      $612,750 based upon the difference between the fair market value and the
      exercise price of the options.

      In July 2000, the Company entered into an agreement with a consultant to
      serve as the Company's public relations agent. The consultant is paid a
      monthly retainer of $6,000 and received options to purchase 75,000 shares
      of the Company's common stock: 25,000 are exercisable at $5.75 per share,
      25,000 at $6.50 per share and 25,000 at $7.50 per share. After an initial
      four-month term, the Company may terminate the agreement on thirty days
      notice. During the year ended December 31, 2000, the Company recorded a
      non-cash charge associated with such options in the amount of $160,314.
      The options were vested and exercisable at December 31, 2000. No charge
      was recorded for the year ended December 31, 2001.

      In connection with the development of its licensed technologies the
      Company entered into a consulting agreement with the scientist who
      developed such technologies, under which the consultant serves as the
      Company's Chief Scientific Advisor. The scientist, who is a stockholder,
      has been paid an annual consulting fee of $75,000. The agreement, which
      commenced in January 1996 and is only cancelable by the Company for cause,
      as defined in the agreement, had an initial term of two years and provided
      for automatic renewals of three additional one year periods unless either
      party notifies the other of its intention not to renew. Research and
      development expense


                                     F-18
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      incurred under the agreement amounted to $75,000 and $75,000 for the years
      ended December 31, 2000 and 1999, respectively. In June 2001, the Company
      entered into an amended consulting agreement with the scientist under
      which the scientist will provide services to the Company for a three year
      period commencing on September 10, 2001. In consideration for the
      consulting services the scientist will be paid an annual fee of $50,000
      payable quarterly. In addition, the Company granted the scientist options
      to purchase 225,000 shares of common stock at $3.94 per share. On
      September 10, 2001, ten percent of the options vested and the remaining
      shall vest in 36 monthly installments beginning on October 10, 2001. For
      the years ended December 31, 2002 and 2001, the Company recorded a charge
      of $58,904 and $79,000, respectively. In September 2002, the Company and
      the consultant terminated their arrangement and all unvested options were
      forfeited.

      In August 2000, the Company entered into an agreement with a consultant to
      provide the Company with financial consulting, planning, structuring,
      business strategy, and public relations services and raising equity
      capital. The term of the agreement is for a period of fifteen months with
      a guarantee of a six-month retention from August 1, 2000, through February
      1, 2001. The consultant was paid a fee of $40,000 upon signing of the
      agreement, and will be paid an additional $40,000 every two months for the
      term of the agreement unless terminated by the Company at the end of the
      initial six month period. Under the provisions of the agreement, the
      consultant received warrants to purchase 500,000 shares of the Company's
      common stock. 200,000 warrants with an exercise price of $3.63 per share
      vested upon the date of the agreement. Of the remaining 300,000 warrants,
      100,000 warrants vest on May 1, 2001 with an exercise price of $6.50 per
      share, 100,000 vest on August 1, 2001 with an exercise price of $7.50 per
      share and 100,000 vest on October 1, 2001 with an exercise price of $9.50
      per share. The warrants become exercisable over a period of five years.
      Unvested warrants terminate in the event the agreement is terminated.
      During the year ended December 31, 2000, the Company recorded a non-cash
      charge associated with such warrants in the amount of $645,786. In January
      2001 the Company and the consultant terminated their arrangement. In
      addition to the cancellation of 300,000 unvested warrants, the consultant
      agreed to return 150,000 of its vested warrants to the Company. In
      connection with the cancellation and return of the vested warrants, the
      Company recorded a non-cash benefit of $535,000 in the results of its
      operations for the year ended December 31, 2001.

      In January 2000 the Company entered into a one year consulting agreement
      with a member of its Board of Directors. In exchange for the consulting
      services, the Company granted the member of the Board warrants to purchase
      50,000 shares of common stock at an exercise price of $1.00. The warrants
      vested immediately and became exercisable on January 19, 2001. During the
      year ended December 31, 2001 and December 31, 2000, the Company recorded a
      non-cash charge associated with such warrants in the amount of $35,402 and
      $134,598, respectively.

      In September 1999 the Company entered into a consulting agreement with one
      of its directors under which the director will provide the Company with
      business valuation services in exchange for warrants to purchase 100,000
      shares of the Company's common stock, at an exercise price of $1.00 per
      share. Of these warrants, 50,000 were exercisable on the date of grant and
      the remaining 50,000 on the first anniversary of the consulting agreement.
      The warrants must be exercised on or prior to September 9, 2004. The
      Company recognized non-cash compensation expense of $108,202 and $46,848
      for the years ended December 31, 2000 and 1999, respectively, based upon
      the fair value of such warrants. All the warrants were vested and
      exercisable at December 31, 2000.



                                     F-19
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      In June 1998 the Company granted a consultant options to purchase 150,000
      shares of the Company's common stock at an exercise price of $5.00 per
      share. 50,000 options vested immediately, and the remaining 100,000 vest
      pro rata over a period of ten quarters. The options have a term of five
      years. The Company recognized non-cash compensation expense of $41,424 and
      $58,480 for the years ended December 31, 2000 and 1999, respectively,
      based upon the fair value of the options on the date of the grant.

      In May 1998, the Company granted a consultant options to purchase 5,000
      shares of the Company's common stock, at an exercise price of $4.25. The
      Company recognized non-cash compensation expense of $15,655 for the year
      ended December 31, 1998 based upon the fair value of such options on the
      date of the grant.

      In January 1998 the Company issued warrants to a third party to purchase
      16,216 shares of the Company's common stock, at an exercise price of $4.60
      per share in connection with an operating lease. The Company recognized a
      non-cash charge of $57,875 for the year ended December 31, 1998 based upon
      the fair value of such warrants on the date the grant.

      In September 1997, in connection with the Company's IPO, the Company
      issued the underwriters warrants to purchase 225,000 shares of common
      stock at an exercise price of $8.25 per share. All the warrants, which
      have a term of five years, are exercisable at December 31, 1999.

      In November 1996, the Company entered into an employment agreement with
      its former President and Chief Executive Officer. Under the terms of the
      agreement, the employee received warrants to purchase 461,016 shares of
      common stock at $3.00 per share. These warrants expire on November 18,
      2006. Upon termination of the employment agreement on April 21, 1998,
      230,508 unvested warrants were surrendered to the Company. 230,508 of the
      warrants are still outstanding at December 31, 2002.

5.    Related Parties

      Employment agreements

      In September 1998, the Company and its Chief Executive Officer and
      Chairman ("EVPs") entered into employment agreements commencing October 1,
      1998 and expiring on December 31, 2000. Under the agreements, the EVPs
      were each paid an annual minimum compensation of $225,000, and were
      granted a minimum of 16,666 options to purchase shares of the Company's
      common stock per annum. The Company incurred $450,000 of expense for the
      year ended December 31, 1999 pursuant to these agreements.

      In November 1999, the EVPs were each granted non-qualified stock options
      to purchase 150,000 shares under the Company's 1996 Incentive and
      Non-Qualified Stock Option Plan, at an exercise price of $1.30, which
      expire in ten years. 37,500 options vested immediately, 75,000 vested in
      November 2000, and the remaining 37,500 vested in November 2001.

      In January 2000, the Company entered into new employment agreements with
      its EVPs, expiring in January 2005. The new agreements provide for an
      annual salary of $250,000, with annual increases of at least 5%. In
      addition, both of the EVPs were granted fully-vested options to purchase
      500,000 shares of the Company's common stock at $2.00 per share. Under the
      provisions of the agreements, the EVPs would each receive a cash payment
      equal to 1.5% of the


                                     F-20
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      total consideration received by the Company in a transaction resulting in
      a greater than 50% change in ownership of the outstanding common stock of
      the Company.

      On March 30, 2001, the Company, its EVPs and certain investors (the
      "Investors") in the Company entered into an agreement under which the
      EVP's agreed to resign from SIGA and use their best efforts to cause each
      of the current directors of SIGA to resign. Under the agreement, certain
      Investors were to be appointed as Chairman of the Board and as Chief
      Executive Officer. In addition, as prescribed in the agreement, the
      amended employment agreement entered into by the Company and the EVPs in
      October 2000 was terminated with no cost to the Company, the vesting of
      37,500 options granted to the EVPs was accelerated, exercise terms were
      extended and the EVPs are entitled to certain benefits until April 2003.
      In addition, each of the parties to the agreement have agreed to lock up
      their respective shares of common stock and options of SIGA for 24 months
      subject to certain release provisions. In connection with the amendment of
      the terms of the EVP's options, the Company recorded a non-cash charge of
      $73,000 in the year ended December 31, 2001.

      In January 2000, the Company amended its employment agreement with its
      CFO, extending his employment until April 2002. Under this amendment, the
      CFO received options to purchase 100,000 shares of the Company's common
      stock at $2.00 per share. The options vest ratably over two years and
      expire in January 2010.

      In October 2000, the Company entered into an amended and restated
      employment agreements with its Chief Executive Officer, its Chairman and
      its CFO. Under the amended agreements, in the event of a change in
      control, the EVPs and the CFO will be paid their respective compensation
      for the remainder of their employment terms and will receive a tax
      gross-up payment. In addition, in such event, all unvested options held by
      the EVPs and the CFO will become vested and exercisable. In the event of a
      merger or consolidation where the holders of the voting capital stock of
      the Company immediately prior to the transaction own less than a majority
      of the voting capital stock of the surviving entity, the EVPs will each
      receive a one time cash payment of 1.5% of the total consideration
      received by the Company and a tax gross-up payment. In the event of a
      sale, merger or public spin-out of any subsidiary or material asset of the
      Company, the EVPs shall each receive a fee equal to 1.5% of the value of
      the Company's shares of the subsidiary or material asset and a tax
      gross-up payment.

      In January 2002, the Company and its Chief Financial Officer ("CFO")
      entered into an amendment to the CFO's employment agreement, extending his
      employment until December 31, 2002. In November 2002, the employment
      agreement was amended and extended until September 30, 2004. Under the
      amended agreement, compensation is set at an annual minimum base salary of
      $210,000 and options of 150,000 were granted under the Plan at an exercise
      price of $2.50 per share. Of such grant, 75,000 shares vested immediately
      and 75,000 shares will vest on September 1, 2003.

      In May 2000, the Company and its Vice President for Research entered into
      an amendment of the Vice Presidents employment agreement, extending his
      employment until December 31, 2002, except that the Company may terminate
      the agreement upon 180 days written notice. Under the amendment the
      employee's title was changed to Chief Scientific Officer ("CSO"). The CSO
      was granted options to purchase 125,000 shares of the Company's common
      stock at $2.00 per share. The options vest ratably over the remaining term
      of the amendment. During the year ended


                                     F-21
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      December 31, 2001 and 2000, the Company recorded non-cash compensation
      charges of $112,168 and $130,999 related to these options, respectively.
      In October 2002, the employment agreement was amended and extended until
      December 31, 2005. Under the amended agreement, compensation is set at an
      annual minimum base salary of $210,000 and options of 300,000 shares were
      granted at an exercise price of $2.50. Upon such grant, the CSO was
      required to surrender 50,000 shares granted under a previous grant with an
      exercise price of $3.94. Under the new grant, 75,000 shares vested
      immediately and 75,000 shares will vest on September 1, 2003, 2004 and
      2005, respectively, pursuant to the Plan. As such, 50,000 options are
      considered variable options under APB 25 as replacement awards for the
      options surrendered. For the year ended December 31, 2002, there was no
      stock compensation charge as the fair value of the options was below the
      exercise price.

      In November 1999, the Company entered into two year employment agreements
      with three newly-hired Vice Presidents ("VPs"), of Business Development,
      Investor Relations, and Marketing, at annual salaries of $95,000,
      $100,000, and $120,000, respectively. Each VP was also granted options to
      purchase 100,000 shares of the Company's common stock at an exercise price
      of $1.125 per share, to vest ratably over two years. As of December 31,
      2001, the VPs were no longer with the Company. The employees forfeited
      12,500 and 100,000 unvested options at December 31, 2001 and 2000,
      respectively.

      In June 2001, the Company entered into an employment agreement with an
      individual to serve as the Company's President and Chief Executive Officer
      (the "Executive"), expiring in June 2003. The agreement provides for an
      annual salary of $300,000. In addition the Executive was granted options
      to purchase 420,000 shares of the Company's common stock at $3.94 per
      share. In October 2001, the Company and the Executive entered into a
      separation and release agreement under which the Company will pay the
      Executive $40,000 over a period through October 5, 2002. Options
      previously granted to the Executive have been cancelled.

6.    Income Taxes

      The Company has incurred losses since inception, which have generated net
      operating loss carryforwards of approximately $19,356,114 and $16,575,000,
      respectively, at December 31, 2002 and 2001 for federal and state income
      tax purposes. These carryforwards are available to offset future taxable
      income and begin expiring in 2010 for federal income tax purposes. As a
      result of a previous change in stock ownership, the annual utilization of
      the net operating loss carryforwards is subject to limitation.

      The net operating loss carryforwards and temporary differences, arising
      primarily from deferred research and development expenses result in a
      noncurrent deferred tax asset at December 31, 2002 and 2001 of
      approximately $11,143,534 and $9,811,000, respectively. In consideration
      of the Company's accumulated losses and the uncertainty of its ability to
      utilize this deferred tax asset in the future, the Company has recorded a
      valuation allowance of an equal amount on such date to fully offset the
      deferred tax asset.

      For the years ended December 31, 2002 and 2001, the Company's effective
      tax rate differs from the federal statutory rate principally due to net
      operating losses and other temporary differences for which no benefit was
      recorded, state taxes and other permanent differences.



                                     F-22
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

7.    Technology Purchase Agreement

      In February 1998, the Company entered into an agreement with a third party
      pursuant to which the Company acquired the third party's right to certain
      technology, intellectual property and related rights in the field of gram
      negative antibiotics in exchange for 335,530 shares of the Company's
      common stock. Research and development expense related to this agreement
      amounted to $1,457,458 for the year ended December 31, 1998.

8.    Collaborative Research and License Agreement

      In October 2002, the Company entered into a collaborative research
      agreement with Trans Tech Pharma, Inc. (Trans Tech), a related party, for
      the discovery and treatment of human diseases. Under the terms of the
      agreement, Trans Tech and the Company have agreed to contribute each of
      their respective services and share in equal costs of specified research
      projects. In consideration of the services performed by Trans Tech and use
      of its proprietary technology, SIGA grants an exclusive, fully-paid,
      nontransferable, nonsublicenseable, limited license to use existing rights
      to patents and technologies. Both parties will share equally in the
      ownership of compounds and related intellectual property derived from such
      research efforts.

      In July 1997, the Company entered into a collaborative research and
      license agreement with Wyeth-Ayerst (the "Collaborator"). Under the terms
      of the agreement, the Company has granted the collaborator an exclusive
      worldwide license to develop, make, use and sell products derived from
      specified technologies. The agreement required the collaborator to sponsor
      further research by the Company for the development of the licensed
      technologies for a period of two years from the effective date of the
      agreement, in return for payments totaling $1,200,000. In consideration of
      the license grant the Company is entitled to receive royalties equal to
      specified percentages of net sales of products incorporating the licensed
      technologies. The royalty percentages increase as certain cumulative and
      annual net sales amounts are attained. The Company could receive milestone
      payments, under the terms of the agreement of up to $13,750,000 for the
      initial product and $3,250,000 for the second product developed from a
      single compound derived from the licensed technologies. Such milestone
      payments are contingent upon the Company making project milestones set
      forth in the agreement, and, accordingly, if the Company is unable to make
      such milestones, the Company will not receive such milestone payments.
      During 1999, the Company recognized $337,500 in revenue related to this
      agreement. In 2000, the Company received $450,000 from the Collaborator.
      The Company recorded the entire amount as deferred revenue on December 31,
      2000 and recognized it in its results of operations upon the signing of an
      amendment to the agreement in May 2001. In addition, for the year ended
      December 31, 2001, the Company recorded $575,000 in revenue relating to
      the agreement of which $237,500 reflected a milestone payment. The
      sponsorship of the research at SIGA ended in September 2001. Research and
      development efforts continue at Wyeth, however, the remaining contractual
      milestones have not been reached as of December 31, 2002.

9.    License and Research Agreements

      In December 2002, the Company announced that it was awarded an initial
      U.S. Government contract with the U.S. Army to develop an effective
      smallpox antiviral drug. The total estimated revenue under the contract is
      $1.6 million for the periods January 1, 2003 to May 31, 2007.


                                     F-23
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      In May 2002 the Company announced that it was awarded a Phase II research
      grant for a total of $865,000. The grant will support the Company's
      antibiotic development program. The grant was awarded by the Small
      Business Innovation Research Program of the National Institutes of Health.
      The Company will receive $529,359 over the twelve month period beginning
      June 1, 2002 and an additional $335,698 over the twelve month period
      beginning June 1, 2003. For the twelve months ended December 31, 2002, the
      Company received approximately $270,000 from this grant.

      On December 6, 2000 the company entered into an exclusive license
      agreement and a sponsored research agreement with the Regents of the
      University of California (the "Regents"). Under the license agreement the
      Company obtained rights for the exclusive commercial development, use and
      sale of products related to certain inventions in exchange for a
      non-refundable license issuance fee of $15,000 and an annual maintenance
      fee of $10,000. In the event that the Company sub-leases the license, it
      shall pay Regents 15% of all royalty payments made to SIGA. Under the
      agreement, SIGA is required to pay Regents 15% of all funds received from
      Wyeth-Ayesrt and a minimum annual amount of $250,000 for the continued
      development of the inventions for a period of three years. Under the
      sponsored research agreement SIGA was required to provide the Regents with
      funding in the total amount of $300,000 over a period of two years to
      support certain research. In September 2001 the sponsored research
      agreement was terminated. The Company recorded total research and
      development charges in the amount of $52,500 for the year ended December
      31, 2000, related to the two agreements.

      In February 2001, the Company entered into a subcontract agreement with
      the Oregon State University. Under the agreement, the Oregon State
      University subcontracted to SIGA certain duties it has under a grant
      received from the National Institute of Health for the development of
      Proxvirus Proteinase Inhibitors. The term of the original agreement lapses
      on August 31, 2001. The agreement has been extended through August 31,
      2003. During the year ended December 31, 2002, the Company recognized
      revenue in the amount of $75,000.

      In March 2000 the Company entered into an agreement with the Ross Products
      Division of Abbott Laboratories (Ross), under which the Company granted
      Ross an exclusive option to negotiate an exclusive license to certain
      Company technology and patents, in addition to certain research
      development services. In exchange for the research services and the
      option, Ross was obligated to pay the Company $120,000 in three
      installments of $40,000. The first payment of $40,000 was received in
      March 2000 and is being recognized ratably, over the expected term of the
      arrangement. The remaining installments are contingent upon meeting
      certain milestones under the agreement and will be recognized as revenue
      upon completion and acceptance of such milestones. The first milestone was
      met, and the Company received an additional payment of $40,000 in the
      quarter ended September 30, 2000. During the years ended December 31, 2001
      and 2000, the Company recognized revenue in the amount of $45,000 and
      $80,000, respectively. The Company has not entered into any new research
      agreements with Ross in 2002.

      In May, August and September 2000 the Company was awarded three Phase I
      Small Business Innovation Research (SBIR) grants from the National
      Institutes for Health in the amounts of $26,000, $96,000 and $125,000
      respectively. The grants are for the periods May 3, 2000 to August 31,
      2000, August 1, 2000 to January 31, 2001, and September 15, 2000 to March
      14, 2001 respectively, and will support the Company's antibiotic and
      vaccine development programs.


                                     F-24
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      In July and September, 1999 the Company was awarded two Phase I research
      grants by the Small Business Innovation Research Program (SBIR) of
      $109,072 and $293,446 respectively. The first grant was to help support
      the Company's antibiotic discovery efforts for the period July 1, 1999
      through December 31, 1999. The second grant provides support for the
      Company's effort to develop a vaccine targeting strep throat, in
      collaboration with the National Institutes of Health (NIH). The grant
      award is for a period of twelve months beginning on October 1, 1999. For
      the years ending December 31, 2000 and 1999 the Company had recognized
      revenue from the two grants of $220,457 and $182,061, respectively.

10.   Product Development Agreement

      In October 1999 the Company entered into an agreement with Open-iMedia, a
      software and web development company ("Development Company"). Under the
      terms of the agreement the Company was to acquire and the Development
      Company was to develop, the source code for a client/server chat and
      instant messaging application. In March 2000, the Company entered into an
      agreement with the Development Company for creative and technical
      services, and for business strategy consulting in exchange for $280,000 in
      cash and 13,605 shares of the Company's common stock.

      During the year ended December 31, 2000 the Company recognized charges of
      $180,000 and $500,334 associated with cash paid and 102,721 shares of the
      Company's common stock, respectively, paid and granted under the
      agreements. Costs related to this agreement were recognized as the
      services were performed or upon meeting certain milestones as defined
      under the agreements. The Company recorded all amounts paid under the
      development agreements, including the fair value of shares issued in
      research and development expenses.

      In July 2000 the Company acquired a 12.5% equity position in the
      Development Company. Under the terms of the agreement, the Development
      Company received: (i) $170,000 in cash; (ii) 40,336 shares of the
      Company's common stock; and (iii) certain assets consisting of the instant
      messenger product, PeerFinder and fixed assets with a net book value of
      $80,697. In addition, the Company received the right to appoint one
      director to the Development Company's board of directors. At December 31,
      2002 and 2001, the Company reassessed the value of its investment in
      Open-I. The Company reviewed certain events and changes in circumstances
      indicating that the carrying amount of the investment in Open-I may not be
      recoverable in its entirety. In 2000, management elected to reduce the
      carrying amount of its investment to reflect its recoverable value as of
      the year-end and recorded an impairment charge of $156,000. At December
      31, 2001, management reviewed all available information and as a result of
      its analysis determined that the carrying value of its investment should
      be written off.

11.   Other Agreements

      In March 2002, the Company entered into a non-binding Letter of Intent
      (the "Letter") to acquire all of the outstanding shares of Allergy
      Therapeutics Holdings Ltd. ("Allergy"). Under the terms of the letter,
      SIGA was to issue shares to the Allergy Stockholders that would result in
      47.5% ownership to each of the former shareholders of SIGA and former
      shareholders of Allergy of the outstanding common stock, on a fully
      diluted basis. As part of the transaction, Elan Pharma International
      Limited ("Elan") was to enter into an exclusive license for certain
      technology with SIGA in exchange for 5% of the Company's common stock on a
      fully diluted basis. In July 2002,


                                     F-25
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      the Company announced the termination of the Letter to acquire all the
      shares of Holdings due to unfavorable market conditions that existed at
      the time of the termination. The Company incurred approximately $600,000
      of expenses in connection with this contemplated transaction, of which
      approximately $200,000 were still outstanding as of December 31, 2002.

      In May 2000, the Company entered into a letter of intent (the "Letter") to
      acquire Hypernix Technologies, Ltd, an Israel-based entity. Under the
      letter, in the event that the transaction was consummated, SIGA was to
      issue 3 million shares of its common stock to the stockholders and certain
      employees of Hypernix and assume all of the liabilities of Hypernix (not
      to exceed $1,250,000), with Hypernix's creditors to be paid half in cash
      and half in common stock of SIGA. Also under the letter, SIGA was to lend
      Hypernix $250,000 per month for up to five months. This advance was
      subject to interest at an annual rate of 10% and was collateralized by all
      the assets of Hypernix. The Company advanced Hypernix $261,000 and
      $250,000 in May and July 2000,respectively, under the agreement. On August
      10, 2000, the Company terminated the letter of intent. SIGA recorded
      charges of $261,000 and $250,000 for the three months ended June 30, 2000
      and September 30, 2000 respectively, to reserve the amounts advanced to
      Hypernix. In March 2001, the Company received a payment from Hypernix in
      the amount of $84,375.

12.   Segments

      Since the announcement in September 1999 that the Company intended to
      pursue an Internet initiative, the Company operated its Internet
      initiative as a separate segment. The Internet segment generated operating
      expenses of approximately $1,018,000 during 2000 and has no identifiable
      assets at December 31, 2002 and 2001. At December 31, 2002 and 2001 the
      Company has no internet related operations.

13.   Commitments and Contingencies

      Operating lease commitments

      The Company leases certain facilities and office space under operating
      leases. Minimum future rental commitments under operating leases having
      noncancelable lease terms in excess of one year are as follows:

      Year ended December 31,
      2003                                       $164,115
      2004                                        173,821
      2005                                         66,982
      2006                                         68,321
      2007 and thereafter                          75,505
                                                 --------

      Total                                      $548,744
                                                 ========

      Capital lease commitments

      In July, August and September 1998, the Company sold certain laboratory
      equipment, computer equipment and furniture to a third party for $493,329,
      $385,422 and $260,333, respectively, under sale-leaseback agreements with
      terms of 42 months ending December 1, 2001, January 1,


                                     F-26
<PAGE>

SIGA Technologies, Inc.
(A development stage company)
Notes to Financial Statements
December 31, 2002 and 2001
--------------------------------------------------------------------------------

      2002 and February 1, 2002, respectively. At the end of the respective
      leases, the Company renewed terms for an additional 12 months requiring
      minimum monthly payments of $6,167, $4,818 and $3,254, respectively. The
      Company has an option to purchase the equipment up to 15% of the original
      cost at the end of the renewal lease terms.

      Future minimum lease payments for assets under capital leases at December
      31, 2002 are as follows:


      Year ended December 31, 2003:
                                                               $11,326
                                                               -------

                           Total Minimum Payments               11,326

           Less:  amounts representing interest                    120
                                                               -------

      Present value of future minimum lease payments            11,206

           Less current portion of capital lease obligations    11,206
                                                               -------

      Capital lease obligations, net current portion           $    --
                                                               =======

14.   Subsequent Events

      On February 5, 2003, the Company entered into a 12-month consulting
      agreement in the amount of $249,420 to provide marketing research support.
      Upon being awarded research contracts in excess of $2.0 million from such
      support, the Company is obligated to issue 400,000 fully vested warrants
      at an exercise price of $1.32 with an expiration of 3 years. Upon renewal
      of the agreement, the Company is required to issue an additional 100,000
      warrants with an exercise price set at the date of the renewal with an
      expiration of 3 years. The Company has the right to terminate the
      agreement after six months.



                                     F-27