EXHIBIT 31.1

SECTION 302
CERTIFICATION

I, Michael I.
Ruxin, M.D., certify that:

1.   I have
reviewed this Annual Report on Form 10-KSB of Global Med Technologies, Inc. (the
"Registrant);

2.
Based on my knowledge, this annual report does not contain any untrue statement
of a material fact or omit to state a material fact necessary to make the
statements made, in light of the circumstances under which such statements were
made, not misleading with respect to the period covered by this report;

3.
Based on my knowledge, the financial statements, and other financial information
included in this report, fairly present in all material respects the financial
condition, results of operations and cash flows of the Registrant as of, and
for, the periods presented in this report;

4. The
Registrants other certifying officers and I are responsible for
establishing and maintaining disclosure controls and procedures (as defined in
Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financing
reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f) for the
Registrant and we have:

a)
Designed such disclosure controls and procedures, or caused such disclosure
controls and procedures to be designed under our supervision, to ensure that
material information relating to the Registrant, including its consolidated
subsidiaries, is made known to us by others within those entities, particularly
during the period in which this annual report is being prepared;

b)
Designed such internal controls over financial reporting, or caused such
internal control over financial reporting to be designed under our supervision,
to provide reasonable assurance regarding the reliability of financial reporting
and the preparation of financial statements for external purposes in accordance
with generally accepted accounting principles; c) Evaluated the effectiveness of
the Registrants disclosure controls and procedures and presented in this
report our conclusions about the effectiveness of the disclosure controls and
procedures, as of the end of the period covered by this report based on such
evaluation; and

d)
Disclosed in this Report any change in the Registrants internal control
over financial reporting that occurred during the Registrants most recent
fiscal quarter (the Registrants fourth fiscal quarter in the case of an
annual report) that has materially affected, or is reasonably likely to
materially affect, the Registrants internal control over financial
reporting; and

5. The
registrants other certifying officers and I have disclosed, based on our
most recent evaluation of internal control over financial reporting,, to the
Registrants auditors and the audit committee of Registrants board of
directors (or persons performing the equivalent function):

a) All
significant deficiencies and material weaknesses in the design or operation of
internal control over financial reporting which are reasonably likely to
adversely affect the Registrants ability to record, process, summarize and
report financial information; and

b) Any
fraud, whether or not material, that involves management or other employees who
have a significant role in the registrants internal controls.

| | /s/ Michael I. Ruxin, M.D
Name: Michael I. Ruxin, M.D
Chief Executive Officer
| | -----------------------------------------------------------------------------

Date: February 22, 2007

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