Exhibit 10.19

Non-Employee Director Compensation Summary

CuraGen Corporations (the Company) non-employee
directors are currently: (i) Vincent T. DeVita Jr., M.D.; (ii) David R. Ebsworth, Ph.D.; (iii) John H. Forsgren; (iv) James J. Noble, M.A., F.C.A.; (v) Robert E. Patricelli; (vi) Jonathan M. Rothberg, Ph.D.; and
(vii) Patrick J. Zenner. On March 29, 2006, the Companys Board of Directors (the Board) approved a revised compensation structure for the Companys non-employee directors as follows:

Grant of Options Upon Appointment

Each non-employee director
appointed after the 2006 annual meeting of stockholders will automatically receive an option to purchase 30,000 shares of the Companys common stock upon appointment to the Board. These options will vest 1/3 upon grant, 1/3 upon the first
anniversary of the date of grant, and 1/3 upon the second anniversary of the date of grant. (Vesting will be accelerated upon a 50% or greater change in control of CuraGen Corporation.)

Grant of Additional Stock Options

Each non-employee director who continues to serve on the Board will
automatically receive an option to purchase 15,000 shares of the Companys common stock, granted in conjunction with each years Annual Meeting, such option vesting immediately.

The non-executive Chairman of the Board will receive an option to purchase 7,500 shares of the Companys common stock , granted in conjunction with each years
Annual Meeting (or granted on the date of appointment to the position and prorated for the first fiscal year of appointment, the fiscal year ending with the date of the next regularly scheduled Annual Meeting), such option vesting immediately.

The Audit Committee Chair will receive an option to purchase 5,000 shares of the Companys common stock, granted in conjunction with each years
Annual Meeting (or granted on the date of appointment to the position and prorated for the first fiscal year of appointment, the fiscal year ending with the date of the next regularly scheduled Annual Meeting), such option vesting immediately.

The Compensation Committee Chair and the Nominating & Governance Committee Chair will receive an option to purchase 2,500 shares of the
Companys common stock, granted in conjunction with each years Annual Meeting (or granted on the date of appointment to the position and prorated for the first fiscal year of appointment, the fiscal year ending with the date of the next
regularly scheduled Annual Meeting), such option vesting immediately.



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Payment of Fees: Reimbursement of Travel and Other Expenses

In addition to the above mentioned stock option grants, each non-employee director received an annual retainer of $20,000 for his service on the Board during 2006 and
will receive the same amount in 2007. Additional amounts will be paid to the non-employee directors during 2007 as follows:



|                                                                                                      |  |                |       
|----------------------------------------------------------------------------------------------------- |  | -------------- | ------
|Position                                                                                              |  | AdditionalFees
|Non-Executive Chairman of the Board - Retainer                                                        |  | $              | 30,000
|Audit Committee Chair - Retainer                                                                      |  | $              | 15,000
|Compensation Committee Chair - Retainer                                                               |  | $              | 10,000
|Nominating & Governance Committee Chair - Retainer                                                    |  | $              | 10,000
|Board meeting fee - regular meeting                                                                   |  | $              | 1,500 
|Board meeting fee - telephonic meeting                                                                |  | $              | 750   
|Audit Committee meeting - Each member                                                                 |  | $              | 1,250 
|Compensation Committee meeting - Each member                                                          |  | $              | 1,000 
|Nominating & Governance meeting - Each member                                                         |  | $              | 1,000 
|Audit Committee telephonic meeting - Each member                                                      |  | $              | 1,000 
|Compensation Committee telephonic meeting - Each member                                               |  | $              | 750   
|Nominating & Governance telephonic meeting - Each member                                              |  | $              | 750   
|Per diem for additional work performed on site, in support of Board and/or Committee responsibilities |  | $              | 1,000 

All retainer amounts shall be paid quarterly during the fiscal year. Non-employee directors also receive
reimbursement for reasonable travel and other expenses in connection with attending Board and Committee meetings during the fiscal year.