EXHIBIT 10.47

First Amendment to Loan Agreement among Global Med Technologies,  Inc.,  Michael
I. Ruxin,  M.D.,  eBanker  USA.Com,  Inc. and Heng Fung Finance  Company Limited
dated March 18, 1999.

                       FIRST AMENDMENT TO LOAN AGREEMENTS

     THIS FIRST  AMENDMENT TO LOAN AGREEMENT  ("Agreement")  is made and entered
into this 18th day of March, 1999 by and among GLOBAL MED TECHNOLOGIES,  INC., a
Colorado corporation ("Global"), MICHAEL I. RUXIN, M.D., an individual ("Ruxin")
and eBANKER  USA.COM,  INC., a Colorado  corporation  ("eBanker")  and HENG FUNG
FINANCE COMPANY LIMITED ("Heng Fung Finance").

     WHEREAS,  Global and Fronteer Capital,  Inc.  ("Capital") entered into that
certain Loan Agreement dated August 12, 1998 ("Loan agreement")  whereby Capital
agreed, subject to certain terms,  provisions and conditions among other things,
to  make  available  to  Global  a loan  in the  maximum  principal  balance  of
$1,650,000.00  pursuant to one or more Promissory Notes ("Notes") from Global to
Capital;

     WHEREAS,  pursuant  to that  certain  Assignment,  Assumption  and  Consent
Agreement dated September 11, 1998, by and between  Global,  Ruxin,  Capital and
Fronteer   Development   Finance,   Inc.   ("Development"),   Capital  assigned,
Development  assumed and Global and Ruxin consented to the assignment by Capital
and assumption by Development of the rights,  duties and obligations of the Loan
Agreement;

     WHEREAS, Heng Fung Finance entered into certain Loan Agreement dated August
12, 1998 ("Heng Fung  Finance  Loan  Agreement")  with Global  whereby Heng Fung
Finance agreed, subject to certain term, provisions and conditions,  among other
things to make  available  to Global a loan in the maximum  principal  amount of
$1,500,000  pursuant to one or more promissory notes ("Heng Fung Finance Notes")
from Global to Heng Fung Finance;

     WHEREAS,  pursuant  to that  certain  Loan and  Warrant  Purchase  and Sale
Agreement  dated October 7, 1998 by and between Heng Fung  Finance,  Development
and  Global,  Heng Fung  Finance  sold and  Development  purchased,  among other
things, a portion of the Heng Fung Finance Notes ("Acquired Notes");

     WHEREAS,  on March 4, 1999  Development  merged  into  eBanker  and eBanker
assumed  Development's  rights, duties and obligations under the Loan Agreement,
the Notes and the Acquired Notes;

     WHEREAS,  the  obligation  of  Global  under  the  Loan  Agreement  and the
corresponding  Notes and  Acquired  Notes are  guaranteed  by Ruxin  pursuant to
personal guaranties dated August 12, 1998 ("Guaranty");

     WHEREAS,  the  parties to this  Agreement  desire to amend the terms of the
Loan Agreement and the corresponding Notes and the Acquired Notes; and


     WHEREAS,  capitalized terms not defined in this Agreement which are defined
in the Loan Agreement shall have the meaning set forth in the Loan Agreement.


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     NOW THEREFORE in  consideration  of the premises,  the mutual covenants and
agreements  contained  herein and other  good and  valuable  consideration,  the
receipt, sufficiency and adequacy of which are hereby acknowledged,  the parties
hereto agree as follows:

     1.  Amendment to Section 1.2. The last  sentence of Section 1.2 of the Loan
Agreement (and the Heng Fung Loan Agreement as applicable to the Acquired Notes)
shall be amended so that as amended, it reads as follows:

               If not sooner paid, the entire outstanding principal balance
               of the Notes,  together with all accrued but unpaid interest
               thereon,  all  additional  interest  and all other  sums due
               thereunder,  shall be due and  payable  in full on April 15,
               2000.

     2. Amendment to Section 6.2. Section 6.2(b)(iii) of the Loan Agreement (and
the Heng Fung Loan  Agreement  as  applicable  to the  Acquired  Notes) shall be
amended so that as amended, it reads as follows:

                    i.  Convert  any or all of the amounts due under any of
               the Notes into  common  stock of the  Borrower  ("Conversion
               Shares")  at an  exercise  price  equal to $0.25 per  share.
               Lender shall make such standard  investment  representations
               to  show  an  exemption  from  registration  exists  for the
               issuance of such Conversion Shares.

     3.  Consideration.  At consideration of eBanker's agreement to modify terms
of the Loan  Agreement  (and the Heng Fung Loan  Agreement as  applicable to the
Acquired Notes),  Global hereby agrees to pay to eBanker an additional fee equal
to two percent  (2%) of the total  amount due and  committed  under the Acquired
Notes, the Notes and the Loan Agreement ($53,000).  This fee shall be payable in
the  common  stock of global  by  dividing  the  total  amount of the fee by the
average bid and asked prices of the common stock of Global over the ten business
days prior to the date of this Agreement.

     4.  Confirmation  of Terms of Loan  Agreement  and  Guaranty.  In all other
respects,  the Loan Agreement (and the Heng Fung Loan Agreement as applicable to
the Acquired  Notes) and Guaranty,  described  above,  shall remain  unaffected,
unchanged and unimpaired by reason of this  Agreement.  All Notes made by Global
under the Loan Agreement (and the Heng Fung Loan















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     Agreement  as  applicable  to the  Acquired  Notes shall  automatically  be
modified to comply with the terms of this Agreement.

Executed as of the day and year first written.

                                               eBANKER USA.COM, INC.,
                                               a Colorado corporation

                                               By: /s/ Fai H. Chan
                                                   -----------------------------
                                               Its: Chairman, President and CEO


                                               GLOBAL MED TECHNOLOGIES, INC.
                                               a Colorado corporation

                                               By: /s/ Michael I. Ruxin
                                                  ------------------------------
                                               Its: Chairman and CEO















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