can be reconstructed. Therefore, partial dose reconstructions for individuals with
non-presumptive cancers or fewer than 250 days employment in the class period
may be performed using these.data as appropriate.

Health Endangerment

The Secretary established the health endangerment determination for the class of
employees covered by this report based upon the findings summarized below.

(1) Pursuant to 42 C.F.R. § 83.13(c)(3), NIOSH established that there is a

_ reasonable likelihood that such radiation doses may have endangered the health
of members of the class. Pursuant to 42 C.F.R. § 83.13(c)(3)(ii), NIOSH
specified a minimum duration of employment to satisfy this health endangerment
criterion as “having been employed for a number of work days aggregating at
least 250 work days within the parameters established for this class or in
combination with work days within the parameters (excluding aggregate work day
requirements) established for one or more other classes of employees in the
Cohort.”

(2) NIOSH did not identify any evidence from the petitioners or from other resources
that would establish that the class was exposed to radiation during a discrete
incident likely to have involved exceptionally high-level exposures, such as a
nuclear criticality incident, as defined under 42 C.F.R. § 83.13(c)(3)(i).

(3) The Board concurred with NIOSH's finding that the health of the class may have
been endangered and defined the class according to the 250-workday
requirement specified under 42 C.F.R. § 83.13(c)(3)(ii).

V. Effect and Effective Date of Designation

The Secretary submits this report on the designation of one additional class to the
SEC for review by Congress, pursuant to 42 U.S.C. §§ 7384/(14)(C)(ii) and
7384q(c)(2)(A), as amended by the Ronald W. Reagan National Defense
Authorization Act for Fiscal Year 2005, Pub. L. No. 108-375 (codified as amended in
scattered sections of 42 U.S.C.). Pursuant to 42 U.S.C. § 7384/(14)(C)(ii), as
amended by the Ronald W. Reagan National Defense Authorization Act for Fiscal
Year 2005, Pub. L. No. 108-375 (codified as amended in scattered sections of 42
U.S.C.), the designation in this report will become effective 30 days after the date of
‘this report’s submission to Congress “unless Congress otherwise provides.”

VI. Administrative Review of Designation

The health endangerment determination of the designation provided in this report
may be subject to an administrative review within HHS, pursuant to 42 C.F.R. §
83.18(a). On the basis of such a review, if the Secretary decides to expand the class
of employees covered by this designation, the Secretary would transmit a
supplementary report to Congress providing the expanded employee class definition
and the criteria and findings on which the decision was based.

HHS Special Exposure Cohort Designation: 4
Mallinckrodt Chemical Co., Destrehan St. Plant



HHS Designation of Additional Members of the

Special Exposure Cohort
under the
Energy Employees Occupational IIIness Compensation Program Act of 2000

Designating a Class of Employees from

Mallinckrodt Chemical Co., Destrehan St. Plant
St. Louis, Missouri

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avez

HHS Special Exposure Cohort Designation:
Mallinckrodt Chemical Co., Destrehan St. Plant


IL. Designation

|, Michael O. Leavitt, Secretary of Health and Human Services (Secretary), designate
the class of employees defined in Section II of this report for addition to the Special
Exposure Cohort (SEC), as authorized under the Energy Employees Occupational
Illness Compensation Program Act of 2000 ( ), 42 U.S.C. § 7384q.

——_JAN 76 2009
Date _ Michael O. Leavitt

I. Employee Class Definition

All employees of DOE, its predecessor agencies, and their
contractors and subcontractors who worked in the Uranium
Division at the Mallinckrodt Chemical Co., Destrehan Street
Plant in St. Louis, Missouri, from January 1, 1958 to December
31, 1958, for a number of work days aggregating at least 250
work days, occurring either solely under this employment or in
combination with work days within the parameters established
for one or more other classes of employees included in the
SEC.

Ill. Designation Criteria and Recommendations

Pursuant to 42 U.S.C. § 73844, for the class defined in Section II of this report, the
Secretaty has determined, and the Advisory Board on Radiation and Worker Health
(Board) has recommended, that

(1) it is not feasible to estimate with sufficient accuracy the radiation dose that the
class received; and

(2) there is a reasonable likelihood that such radiation dose may have
endangered the health of members of the class.

The SEC final rule states in 42 C.F.R. § 83.13(c)(1) that it is feasible in two situations
to estimate the radiation dose that the class received with sufficient accuracy. First,
the rule states that radiation doses may be estimated with sufficient accuracy if
NIOSH has established that it has access to sufficient information to estimate the
maximum radiation dose for every type of cancer for which radiation doses are
reconstructed that could have been incurred under plausible circumstances by any
member of the class. Alternatively, radiation doses may be estimated with sufficient
accuracy if NIOSH has established that it has access to sufficient information to
estimate the radiation doses of members of the class more precisely than a
maximum dose estimate.

HHS Special Exposure Cohort Designation: 2
Mallinckrodt Chemical Co., Destrehan St. Plant



The Board, pursuant to 42 U.S.C. § 7384q, advised the Secretary to designate the
class as an addition to the SEC in a letter received by the Secretary on December
22, 2008.

IV... Designation Findings

Eeasibility of Estimating Radiation Doses with Sufficient Accuracy

The Secretary established the feasibility determination for the class of employees
covered by this report based upon the findings summarized below.

(1) The Mallinckrodt Chemical Co. Destrehan Plant was involved in early uranium
processing work for the manufacture of atomic weapons.

(2) The Board already recommended that special exposure status be granted to
employees in the Uranium Division who worked there between 1949 and 1957.
NIOSH reported that there were no substantial differences in site operations or
workplace monitoring practices at this facility for 1958 as compared to the earlier
time period.

(3) NIOSH reported that it was unable to locate sufficient monitoring data or
information on radiological operations at this facility to be able to complete
accurate individual dose reconstructions for the potential internal exposures to
uranium progeny to which these workers may have been subjected.

(4) 42 C.F.R. § 83.14 permits a NIOSH-initiated SEC petition when NIOSH has
attempted to conduct a dose reconstruction for a cancer claimant and finds that
the dose reconstruction cannot be completed because there is insufficient
information to estimate the radiation doses of the claimant with sufficient
accuracy. NIOSH reached this conclusion for a claimant from the Mallinckrodt
Chemical Co., Destrehan St. Plant, St. Louis, MO, and subsequently notified the
claimant and provided information to the claimant about the SEC petitioning
process.

(5) Pursuant to 42 C.F.R. § 83.13(c)(1), NIOSH determined that there is insufficient
information to either: (1) estimate the maximum radiation dose, for every type of
cancer for which radiation doses are reconstructed, that could have been
incurred under plausible circumstances by any member of the class; or (2)
estimate the radiation doses of members of the class more precisely than a
maximum dose estimate.

(6) The Board concurred with the NIOSH evaluation and recommended the
proposed class for addition to the SEC.

* (7) Although NIOSH found that it is not possible to completely reconstruct radiation
doses for these employees, NIOSH intends to use any available internal and
external monitoring data that may be available for an individual claim (and can be
interpreted using existing NIOSH dose reconstruction processes or procedures).
Further, NIOSH has determined that occupational medical dose for all workers

HHS Special Exposure Cohort Designation: 3
Mallinckrodt Chemical Co., Destrehan St. Plant