Exhibit 4.1

 

 



COMBIMATRIX NUMBER   CBMX THIS CERTIFICATE IS TRANSFERABLE IN CANTON, MA, NEW YORK, NY, JERSEY   CITY, NJ, AND PITTSBURGH, PA SHARES CUSIP 20009T 30 3 SEE REVERSE FOR CERTAIN   DEFINITIONS INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE This   certifies that SPECIMEN COUNTERSIGNED AND REGISTERED: COMPUTERSHARE   SHAREOWNER SERVICES LLC TRANSFER AGENT AND REGISTRAR BY: AUTHORIZED SIGNATURE   is the record holder of FULLY PAID AND NONASSESSABLE SHARES OF COMMON STOCK,   $0.001 PAR VALUE, OF COMBIMATRIX CORPORATION transferable on the books of the   corporation in person or by duly authorized attorney upon surrender of this   Certificate properly endorsed. This Certificate is not valid until   countersigned by the Transfer Agent and registered by the Registrar. WITNESS   the facsimile seal of the Corporation and the facsimile signatures of its   duly authorized officers. Dated: DELAWARE SEAL COMBIMATRIX CORPORATION2002   CHIEF FINANCIAL OFFICER AND SECRETARY PRESIDENT & CHIEF EXECUTIVE OFFICER   


    




 










A statement of   the rights, preferences, privileges and restrictions granted to or imposed   upon the respective classes or series of shares of stock of the Corporation   and upon holders thereof as established by the Certificate of Incorporation   or by any Certificate of Designation of Preferred Stock, and the number of   shares constituting each series and the designations thereof, may be obtained   by any shareholder upon request and without charge at the principal office of   the corporation. The following abbreviations, when used in the inscription on   the face of this certificate, shall be construed as though they were written   out in full according to applicable laws or regulations: TEN COM – as tenants   in common TEN ENT – as tenants by the entireties JT TEN – as joint tenants   with right of survivorship and not as tenants in common COM PROP – as   community property UNIF GIFT MIN ACT – Custodian (Cust) (Minor) under Uniform   Gifts to Minors Act (State) UNIF TRF MIN ACT – Custodian (until age ) (Cust)   under Uniform Transfers (Minor) to Minors Act (State) Additional   abbreviations may also be used though not in the above list. FOR VALUE   RECEIVED, _____________________________________________________ hereby   sell(s), assign(s) and transfer(s) unto PLEASE INSERT SOCIAL SECURITY OR   OTHER IDENTIFYING NUMBER OF ASSIGNEE (PLEASE PRINT OR TYPEWRITE NAME AND   ADDRESS, INCLUDING ZIP CODE, OF ASSIGNEE) shares of the capital stock   represented by within Certificate, and do hereby irrevocably constitute and   appoint attorney-in-fact to transfer the said stock on the books of the   within named Corporation with full power of the substitution in the premises.   Dated X X NOTICE: THE SIGNATURE TO THIS ASSIGNMENT MUST CORRESPOND WITH THE   NAME AS WRITTEN UPON THE FACE OF THE CERTIFICATE IN EVERY PARTICULAR, WITHOUT   ALTERATION OR ENLARGEMENT OR ANY CHANGE WHATSOEVER. Signature(s) Guaranteed:   By THE SIGNATURE(S) SHOULD BE GUARANTEED BY AN ELIGIBLE GUARANTOR   INSTITUTION, (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT   UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM),   PURSUANT TO S.E.C. RULE 17Ad-15. GUARANTEES BY A NOTARY PUBLIC ARE NOT   ACCEPTABLE. SIGNATURE GUARANTEES MUST NOT BE DATED.