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  <xsd:element abstract="true" id="stj_AcquiredInProcessResearchAndDevelopmentMember" name="AcquiredInProcessResearchAndDevelopmentMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_AsiaPacificMember" name="AsiaPacificMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_BritishColumbiaClassActionMattersMember" name="BritishColumbiaClassActionMattersMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CardiacRhythmManagementMember" name="CardiacRhythmManagementMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CommercialPaperBorrowingMember" name="CommercialPaperBorrowingMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CommitmentsAndContingenciesLineItems" name="CommitmentsAndContingenciesLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CommitmentsAndContingenciesTable" name="CommitmentsAndContingenciesTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_CostOfSalesBeforeSpecialCharges" name="CostOfSalesBeforeSpecialCharges" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CrmNmdMember" name="CrmNmdMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CustomerListsAndRelationshipsMember" name="CustomerListsAndRelationshipsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_CvAfMember" name="CvAfMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_DaysOfLegalNotice" name="DaysOfLegalNotice" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_DebtInstrumentTerm" name="DebtInstrumentTerm" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="stj_DefinedBenefitPlanPensionSettlementCharge" name="DefinedBenefitPlanPensionSettlementCharge" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
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  <xsd:element abstract="true" id="stj_EuropeMember" name="EuropeMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_FixedRateDebtObligationsCarryingValue" name="FixedRateDebtObligationsCarryingValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="stj_FixedRateDebtObligationsFairValueDisclosure" name="FixedRateDebtObligationsFairValueDisclosure" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
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  <xsd:element abstract="true" id="stj_FourPointEightSevenFivePercentSeniorNotesDueTwoThousandNineteenMember" name="FourPointEightSevenFivePercentSeniorNotesDueTwoThousandNineteenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_GoodwillAndOtherIntangibleAssetsLineItems" name="GoodwillAndOtherIntangibleAssetsLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_IdleFacilityCosts" name="IdleFacilityCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_IndividualOntarioCaseMember" name="IndividualOntarioCaseMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_IntangibleAssetChargesMember" name="IntangibleAssetChargesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_IntangibleAssetsMember" name="IntangibleAssetsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
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  <xsd:element abstract="true" id="stj_InterestRateByTypeAxis" name="InterestRateByTypeAxis" nillable="true" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_InterestRateByTypeDomain" name="InterestRateByTypeDomain" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_InterestRateSwapTerm" name="InterestRateSwapTerm" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="stj_InventoryStepUpAmortization" name="InventoryStepUpAmortization" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_JapanMember" name="JapanMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_LegalAccrualAndInsuranceReceivableTextBlock" name="LegalAccrualAndInsuranceReceivableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_LicensesDistributionAgreementsAndOtherMember" name="LicensesDistributionAgreementsAndOtherMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_LongLivedAssetChargesMember" name="LongLivedAssetChargesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_LongLivedAssets" name="LongLivedAssets" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="stj_LongLivedAssetsByGeographicLocationTableTextBlock" name="LongLivedAssetsByGeographicLocationTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_LongTermDebtMaturitiesRepaymentsOfPrincipalThereafter" name="LongTermDebtMaturitiesRepaymentsOfPrincipalThereafter" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="stj_MaximumMaturityOfUnsecuredCommercialPaper" name="MaximumMaturityOfUnsecuredCommercialPaper" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_MaximumrangeforestimatedcostsMember" name="MaximumrangeforestimatedcostsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_MinimumRangeForEstimatedCostsMember" name="MinimumRangeForEstimatedCostsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_MoneyMarketSecuritiesFairValueDisclosure" name="MoneyMarketSecuritiesFairValueDisclosure" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="stj_NetAverageInterestRate" name="NetAverageInterestRate" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_NetEarningsPerShareLineItems" name="NetEarningsPerShareLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_NetEarningsPerShareTable" name="NetEarningsPerShareTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_NetSalesByGeographicLocationTableTextBlock" name="NetSalesByGeographicLocationTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_NeuromodulationMember" name="NeuromodulationMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_NevadaFederalCourtLawsuitMember" name="NevadaFederalCourtLawsuitMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_NmdMember" name="NmdMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_NumberOfClaimsExpectedToBeAppealed" name="NumberOfClaimsExpectedToBeAppealed" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_NumberOfForm483Observations" name="NumberOfForm483Observations" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_NumberOfInsuranceCarriers" name="NumberOfInsuranceCarriers" nillable="true" substitutionGroup="xbrli:item" type="xbrli:positiveIntegerItemType" xbrli:periodType="instant" />
  <xsd:element id="stj_NumberOfOutstandingClassActions" name="NumberOfOutstandingClassActions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="stj_NumberOfProposedClassActions" name="NumberOfProposedClassActions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="stj_OnePointFiveEightPercentYenDenominatedSeniorNotesDueTwoThousandSeventeenMember" name="OnePointFiveEightPercentYenDenominatedSeniorNotesDueTwoThousandSeventeenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_OntarioClassActionMattersMember" name="OntarioClassActionMattersMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_OtherCostsMember" name="OtherCostsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_OtherCountriesMember" name="OtherCountriesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_OtherDebtCarryingValue" name="OtherDebtCarryingValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="stj_OtherIncomeExpense" name="OtherIncomeExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="stj_OtherRestructuringTypeItems" name="OtherRestructuringTypeItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_OtherSegmentMember" name="OtherSegmentMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_OutstandingClassActions" name="OutstandingClassActions" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="stj_ProceedsFromTerminationOfInterestRateSwap" name="ProceedsFromTerminationOfInterestRateSwap" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="stj_PurchasedInProcessResearchAndDevelopmentIprdAndSpecialChargesLineItems" name="PurchasedInProcessResearchAndDevelopmentIprdAndSpecialChargesLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_RegulatoryMattersSylmarCaMember" name="RegulatoryMattersSylmarCaMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_RemainingInsuranceCoverageForClaims" name="RemainingInsuranceCoverageForClaims" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="stj_RestructuringReservedPeriodExpenseContractTermination" name="RestructuringReservedPeriodExpenseContractTermination" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="stj_ScheduleOfNetSalesAndOperatingProfitByReportableSegmentTableTextBlock" name="ScheduleOfNetSalesAndOperatingProfitByReportableSegmentTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_ScheduleOfOtherIncomeExpenseNetTableTextBlock" name="ScheduleOfOtherIncomeExpenseNetTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_SeveranceAndBenefitCostsNumberOfEmployeesImpacted" name="SeveranceAndBenefitCostsNumberOfEmployeesImpacted" nillable="true" substitutionGroup="xbrli:item" type="xbrli:positiveIntegerItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_SilzoneInsuranceReceivable" name="SilzoneInsuranceReceivable" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="stj_SilzoneLossContingencyAccrualAtCarryingValue" name="SilzoneLossContingencyAccrualAtCarryingValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="stj_SilzoneProductLiabilityInsuranceFinalLayerMember" name="SilzoneProductLiabilityInsuranceFinalLayerMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_SpecialCharges" name="SpecialCharges" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_SpecialChargesAbstract" name="SpecialChargesAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_SpecialChargesTextBlock" name="SpecialChargesTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_StjReclassificationofacquirediprd" name="StjReclassificationofacquirediprd" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
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  <xsd:element id="stj_TotalSpecialCharges" name="TotalSpecialCharges" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_TrademarksAndTradenamesMember" name="TrademarksAndTradenamesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_TwoPointFivePercentSeniorNotesDueTwoThousandSixteenMember" name="TwoPointFivePercentSeniorNotesDueTwoThousandSixteenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_TwoPointTwoPercentSeniorNotesDueTwoThousandThirteenMember" name="TwoPointTwoPercentSeniorNotesDueTwoThousandThirteenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_TwoPointZeroFourPercentYenDenominatedSeniorNotesDueTwoThousandTwentyMember" name="TwoPointZeroFourPercentYenDenominatedSeniorNotesDueTwoThousandTwentyMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_UnitedStatesMember" name="UnitedStatesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_VolcanocorpvsLightlabMember" name="VolcanocorpvsLightlabMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_VolcanocorpvsStJudemedicalMember" name="VolcanocorpvsStJudemedicalMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="stj_WeightedAverageInterestRate" name="WeightedAverageInterestRate" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_WeightedAverageSharesOutstanding" name="WeightedAverageSharesOutstanding" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_YenDenominatedCreditFacilitiesDueTwoThousandThirteenMember" name="YenDenominatedCreditFacilitiesDueTwoThousandThirteenMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_YenDenominatedCreditFacilitiesMember" name="YenDenominatedCreditFacilitiesMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_YenDenominatedCreditFacilityOneMember" name="YenDenominatedCreditFacilityOneMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="stj_YenDenominatedCreditFacilityTwoMember" name="YenDenominatedCreditFacilityTwoMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
</xsd:schema>
</XBRL>