ORAU Team

NIOSH Dose Reconstruction Project

Technical Information Bulletin: IMBA Organ and IREP Model 

Selection by ICD-9 Code

Document No.: 

ORAUT-OTIB-0005

Effective Date: 11/03/2003

Revision No.: 00

Controlled Copy No.: _________

Page 1 of 24

Subject Expert: Scott R. Siebert

Approval: Signature on File____________ Date: 11/30/2003

 James P. Griffin, Task 5 Manager 

Concurrence: Signature on File ________ Date: 12/03/2003 Richard E. Toohey, Project Director 

Approval: Signature on File____________ Date: 12/03/2003

 James W. Neton, NIOSH, OCAS Health Science Administrator

Supersedes: None

RECORD OF ISSUE/REVISIONS

ISSUE

AUTHORIZATION 

DATE

EFFECTIVE

DATE

REV. 

NO. DESCRIPTION

Draft 10/15/2003 00-A ORAU technical information bulletin to 

clarify IMBA organ and IREP model 

selection. Initiated by Elizabeth Brackett. 

Draft 11/03/2003 00-B Incorporates comments from NIOSH and 

ORAU team members.

11/03/2003 11/03/2003 00

First approved issue. Initiated by 

Elizabeth Brackett. 
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 2 of 24

IMBA Organ and IREP Model Selection by ICD-9 Code

1.0 Purpose

This Technical Information Bulletin provides guidance on selecting appropriate ICRP modeled 

organs/tissues in the Integrated Modules for Bioassay Analysis (IMBA) software program to estimate 

the internal dose for specific ICD-9 codes and the appropriate model in the Interactive 

RadioEpidemiological Program (IREP). 

2.0 Background

Under EEOICPA, the organs/tissues for which doses must be estimated are those delineated by the 

specified ICD-9 code received from the Department of Labor (DOL). While many ICD-9 codes are 

clear in their intended organ/tissue, additional guidance is necessary to identify the appropriate IMBA 

and IREP model to use for the organ/tissue. This TIB designates the appropriate organ/tissue 

selection within IMBA to use for the various ICD-9 coded cancers, and the appropriate IREP model to 

use as well.

3.0 Guidance

The following table correlates ICD-9 codes to the appropriate organ/tissue selection in IMBA and the 

appropriate IREP model. Organs/tissues labeled “Highest non-met organ/tissue” indicate that dose to 

the highest non-metabolic organ is to be used to represent the dose to the ICD-9 Code designated 

organ/tissue. A discussion of this term is included in section 4.0 of this bulletin. The remaining 

regions are described by the term used in IMBA. 

Table 1 

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

140 MALIGANT NEOPLASM LIP 

140.0 MALIG NEO UPPER VERMILION Highest non-met organ/tissue Oral Cav and pharynx

140.1 MALIG NEO LOWER VERMILION Highest non-met organ/tissue Oral Cav and pharynx

140.3 MALIG NEO UPPER LIP, INNER Highest non-met organ/tissue Oral Cav and pharynx

140.4 MALIG NEO LOWER LIP, INNER Highest non-met organ/tissue Oral Cav and pharynx

140.5 MALIG NEO LIP, INNER NOS Highest non-met organ/tissue Oral Cav and pharynx

140.6 MALIG NEO LIP, COMMISSURE Highest non-met organ/tissue Oral Cav and pharynx

140.8 MALIG NEO LIP NEC Highest non-met organ/tissue Oral Cav and pharynx

140.9 MALIG NEO LIP/VERMIL NOS Highest non-met organ/tissue Oral Cav and pharynx

141 MALIG NEO TONGUE 

141.0 MALIG NEO TONGUE BASE Highest non-met organ/tissue Oral Cav and pharynx

141.1 MALIG NEO DORSAL TONGUE Highest non-met organ/tissue Oral Cav and pharynx

141.2 MALIG NEO TIP/LAT TONGUE Highest non-met organ/tissue Oral Cav and pharynx

141.3 MALIG NEO VENTRAL TONGUE Highest non-met organ/tissue Oral Cav and pharynx

141.4 MALIG NEO ANT 2/3 TONGUE Highest non-met organ/tissue Oral Cav and pharynx

141.5 MALIG NEO TONGUE JUNCTION Highest non-met organ/tissue Oral Cav and pharynx

141.6 MALIG NEO LINGUAL TONSIL LNET Oral Cav and pharynx

141.8 MALIG NEO TONGUE NEC Highest non-met organ/tissue Oral Cav and pharynx

141.9 MALIG NEO TONGUE NOS Highest non-met organ/tissue Oral Cav and pharynx
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 3 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

142 MALIG NEO MAJOR SALIVARY 

142.0 MALIG NEO PAROTID Highest non-met organ/tissue Oral Cav and pharynx

142.1 MALIG NEO SUBMANDIBULAR Highest non-met organ/tissue Oral Cav and pharynx

142.2 MALIG NEO SUBLINGUAL Highest non-met organ/tissue Oral Cav and pharynx

142.8 MALIG NEO MAJ SALIVARY NEC Highest non-met organ/tissue Oral Cav and pharynx

142.9 MALIG NEO SALIVARY NOS Highest non-met organ/tissue Oral Cav and pharynx

143 MALIGNANT NEOPLASM GUM 

143.0 MALIG NEO UPPER GUM Highest non-met organ/tissue Oral Cav and pharynx

143.1 MALIG NEO LOWER GUM Highest non-met organ/tissue Oral Cav and pharynx

143.8 MALIG NEO GUM NEC Highest non-met organ/tissue Oral Cav and pharynx

143.9 MALIG NEO GUM NOS Highest non-met organ/tissue Oral Cav and pharynx

144 MALIG NEO MOUTH FLOOR 

144.0 MALIG NEO ANT FLOOR MOUTH Highest non-met organ/tissue Oral Cav and pharynx

144.1 MALIG NEO LAT FLOOR MOUTH Highest non-met organ/tissue Oral Cav and pharynx

144.8 MALIG NEO MOUTH FLOOR NEC Highest non-met organ/tissue Oral Cav and pharynx

144.9 MALIG NEO MOUTH FLOOR NOS Highest non-met organ/tissue Oral Cav and pharynx

145 MALIG NEO MOUTH NEC/NOS 

145.0 MALIG NEO CHEEK MUCOSA Highest non-met organ/tissue Oral Cav and pharynx

145.1 MALIG NEO MOUTH VESTIBULE Highest non-met organ/tissue Oral Cav and pharynx

145.2 MALIG NEO HARD PALATE Highest non-met organ/tissue Oral Cav and pharynx

145.3 MALIG NEO SOFT PALATE Highest non-met organ/tissue Oral Cav and pharynx

145.4 MALIG NEO UVULA Highest non-met organ/tissue Oral Cav and pharynx

145.5 MALIG NEO PALATE NOS Highest non-met organ/tissue Oral Cav and pharynx

145.6 MALIG NEO RETROMOLAR Highest non-met organ/tissue Oral Cav and pharynx

145.8 MALIG NEO MOUTH NEC Highest non-met organ/tissue Oral Cav and pharynx

145.9 MALIG NEO MOUTH NOS Highest non-met organ/tissue Oral Cav and pharynx

146 MALIG NEO OROPHARYNX 

146.0 MALIG NEO TONSIL LNET Oral Cav and pharynx

146.1 MALIG NEO TONSILLAR FOSSA LNET Oral Cav and pharynx

146.2 MALIG NEO TONSIL PILLARS LNET Oral Cav and pharynx

146.3 MALIG NEO VALLECULA ET2 Oral Cav and pharynx

146.4 MALIG NEO ANT EPIGLOTTIS ET2 Oral Cav and pharynx

146.5 MALIG NEO EPIGLOTTIS JUNCT ET2 Oral Cav and pharynx

146.6 MALIG NEO LAT OROPHARYNX ET2 Oral Cav and pharynx

146.7 MALIG NEO POST OROPHARYNX ET2 Oral Cav and pharynx

146.8 MALIG NEO OROPHARYNX NEC ET2 Oral Cav and pharynx

146.9 MALIG NEO OROPHARYNX NOS ET2 Oral Cav and pharynx

147 MALIG NEO NASOPHARYNX 

147.0 MALIG NEO SUPER NASOPHARYN ET2 Oral Cav and pharynx

147.1 MALIG NEO POST NASOPHARYNX ET2 Oral Cav and pharynx

147.2 MALIG NEO LAT NASOPHARYNX ET2 Oral Cav and pharynx

147.3 MALIG NEO ANT NASOPHARYNX ET2 Oral Cav and pharynx

147.8 MALIG NEO NASOPHARYNX NEC ET2 Oral Cav and pharynx

147.9 MALIG NEO NASOPHARYNX NOS ET2 Oral Cav and pharynx
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 4 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

148 MALIG NEO HYPOPHARYNX 

148.0 MALIG NEO POSTCRICOID ET2 Oral Cav and pharynx

148.1 MALIG NEO PYRIFORM SINUS ET2 Oral Cav and pharynx

148.2 MALIG NEO ARYEPIGLOTT FOLD ET2 Oral Cav and pharynx

148.3 MALIG NEO POST HYPOPHARYNX ET2 Oral Cav and pharynx

148.8 MALIG NEO HYPOPHARYNX NEC ET2 Oral Cav and pharynx

148.9 MALIG NEO HYPOPHARYNX NOS ET2 Oral Cav and pharynx

149 OTHER MALIG OROPHARYNX 

149.0 MALIG NEO PHARYNX NOS ET2 Oral Cav and pharynx

149.1 MALIG NEO WALDEYER'S RING LNET Oral Cav and pharynx

149.8 MALIG NEO ORAL/PHARYNX NEC ET2 Oral Cav and pharynx

149.9 MALIG NEO OROPHRYN ILL-DEF ET2 Oral Cav and pharynx

150 MALIG NEO ESOPHAGUS 

150.0 MALIG NEO CERVICAL ESOPHAG Esophagus Esophagus

150.1 MALIG NEO THORACIC ESOPHAG Esophagus Esophagus

150.2 MALIG NEO ABDOMIN ESOPHAG Esophagus Esophagus

150.3 MALIG NEO UPPER 3RD ESOPH Esophagus Esophagus

150.4 MALIG NEO MIDDLE 3RD ESOPH Esophagus Esophagus

150.5 MALIG NEO LOWER 3RD ESOPH Esophagus Esophagus

150.8 MALIG NEO ESOPHAGUS NEC Esophagus Esophagus

150.9 MALIG NEO ESOPHAGUS NOS Esophagus Esophagus

151 MALIGNANT NEO STOMACH 

151.0 MALIG NEO STOMACH CARDIA Stomach Stomach

151.1 MALIG NEO PYLORUS Stomach Stomach

151.2 MALIG NEO PYLORIC ANTRUM Stomach Stomach

151.3 MALIG NEO STOMACH FUNDUS Stomach Stomach

151.4 MALIG NEO STOMACH BODY Stomach Stomach

151.5 MALIG NEO STOM LESSER CURV Stomach Stomach

151.6 MALIG NEO STOM GREAT CURV Stomach Stomach

151.8 MALIG NEO STOMACH NEC Stomach Stomach

151.9 MALIG NEO STOMACH NOS Stomach Stomach

152 MALIG NEO SMALL BOWEL 

152.0 MALIG NEO DUODENUM SI All digestive

152.1 MALIG NEO JEJUNUM SI All digestive

152.2 MALIG NEO ILEUM SI All digestive

152.3 MALIG NEO MECKEL'S DIVERT SI All digestive

152.8 MALIG NEO SMALL BOWEL NEC SI All digestive

152.9 MALIG NEO SMALL BOWEL NOS SI All digestive

153 MALIGNANT NEOPLASM COLON 

153.0 MALIG NEO HEPATIC FLEXURE ULI Colon

153.1 MALIG NEO TRANSVERSE COLON ULI Colon

153.2 MALIG NEO DESCEND COLON LLI Colon

153.3 MALIG NEO SIGMOID COLON LLI Colon

153.4 MALIG NEO CECUM ULI Colon

153.5 MALIG NEO APPENDIX ULI Colon

153.6 MALIG NEO ASCEND COLON ULI Colon

153.7 MALIG NEO SPLENIC FLEXURE LLI Colon

153.8 MALIG NEO COLON NEC Colon Colon

153.9 MALIG NEO COLON NOS Colon Colon
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 5 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

154 MALIG NEO RECTUM/ANUS 

154.0 MALIG NEO RECTOSIGMOID JCT LLI Rectum

154.1 MALIG NEO RECTUM LLI Rectum

154.2 MALIG NEO ANAL CANAL LLI Rectum

154.3 MALIG NEO ANUS NOS LLI Rectum

154.8 MALIG NEO RECTUM/ANUS NEC LLI Rectum

155 MALIGNANT NEOPLASM LIVER 

155.0 MALIG NEO LIVER, PRIMARY Liver Liver

155.1 MALIG NEO INTRAHEPAT DUCTS Gallbladder Gallbladder

155.2 MALIG NEO LIVER NOS Liver Liver

156 MALIG NEO GB/EXTRAHEPATIC 

156.0 MALIG NEO GALLBLADDER Gallbladder Gallbladder

156.1 MALIG NEO EXTRAHEPAT DUCTS Gallbladder Gallbladder

156.2 MALIG NEO AMPULLA VATER Gallbladder Gallbladder

156.8 MALIG NEO BILIARY NEC Gallbladder Gallbladder

156.9 MALIG NEO BILIARY NOS Gallbladder Gallbladder

157 MALIGNANT NEO PANCREAS 

157.0 MALIG NEO PANCREAS HEAD Pancreas Pancreas

157.1 MALIG NEO PANCREAS BODY Pancreas Pancreas

157.2 MALIG NEO PANCREAS TAIL Pancreas Pancreas

157.3 MALIG NEO PANCREATIC DUCT Pancreas Pancreas

157.4 MALIG NEO ISLET LANGERHANS Pancreas Pancreas

157.8 MALIG NEO PANCREAS NEC Pancreas Pancreas

157.9 MALIG NEO PANCREAS NOS Pancreas Pancreas

158 MALIG NEO PERITONEUM 

158.0 MALIG NEO RETROPERITONEUM Highest non-met organ/tissue All digestive

158.8 MALIG NEO PERITONEUM NEC Highest non-met organ/tissue All digestive

158.9 MALIG NEO PERITONEUM NOS Highest non-met organ/tissue All digestive

159 OTHER MALIG NEO GI/PERITON 

159.0 MALIG NEO INTESTINE NOS Colon All digestive

159.1 MALIG NEO SPLEEN NEC Spleen All digestive

159.8 MALIG NEO GI/INTRA-ABD NEC Highest non-met organ/tissue All digestive

159.9 MALIG NEO GI TRACT ILL-DEF Highest non-met organ/tissue All digestive

160 MALIG NEO NASAL CAV/SINUS 

160.0 MALIG NEO NASAL CAVITIES ET1 Other respiratory

160.1 MALIG NEO MIDDLE EAR Highest non-met organ/tissue Other respiratory

160.2 MALIG NEO MAXILLARY SINUS Highest non-met organ/tissue Other respiratory

160.3 MALIG NEO ETHMOIDAL SINUS Highest non-met organ/tissue Other respiratory

160.4 MALIG NEO FRONTAL SINUS Highest non-met organ/tissue Other respiratory

160.5 MALIG NEO SPHENOID SINUS Highest non-met organ/tissue Other respiratory

160.8 MALIG NEO ACCESS SINUS NEC Highest non-met organ/tissue Other respiratory

160.9 MALIG NEO ACCESS SINUS NOS Highest non-met organ/tissue Other respiratory

161 MALIGNANT NEO LARYNX 

161.0 MALIG NEO GLOTTIS ET2 Other respiratory

161.1 MALIG NEO SUPRAGLOTTIS ET2 Other respiratory

161.2 MALIG NEO SUBGLOTTIS ET2 Other respiratory

161.3 MALIG NEO CARTILAGE LARYNX ET2 Other respiratory

161.8 MALIG NEO LARYNX NEC ET2 Other respiratory

161.9 MALIG NEO LARYNX NOS ET2 Other respiratory
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 6 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

162 MALIG NEO TRACHEA/LUNG 

162.0 MALIG NEO TRACHEA Lung Lung

162.2 MALIG NEO MAIN BRONCHUS Lung Lung

162.3 MALIG NEO UPPER LOBE LUNG Lung Lung

162.4 MALIG NEO MIDDLE LOBE LUNG Lung Lung

162.5 MALIG NEO LOWER LOBE LUNG Lung Lung

162.8 MALIG NEO BRONCH/LUNG NEC Lung Lung

162.9 MALIG NEO BRONCH/LUNG NOS Lung Lung

163 MALIGNANT NEOPL PLEURA 

163.0 MALIG NEO PARIETAL PLEURA Highest non-met organ/tissue Other respiratory

163.1 MALIG NEO VISCERAL PLEURA Highest non-met organ/tissue Other respiratory

163.8 MALIG NEO PLEURA NEC Highest non-met organ/tissue Other respiratory

163.9 MALIG NEO PLEURA NOS Highest non-met organ/tissue Other respiratory

164 MALIG NEO THYMUS/MEDIASTIN 

164.0 MALIG NEO THYMUS Thymus Other respiratory

164.1 MALIG NEO HEART Heart Wall Other respiratory

164.2 MALIG NEO ANT MEDIASTINUM Highest non-met organ/tissue Other respiratory

164.3 MALIG NEO POST MEDIASTINUM Highest non-met organ/tissue Other respiratory

164.8 MALIG NEO MEDIASTINUM NEC Highest non-met organ/tissue Other respiratory

164.9 MALIG NEO MEDIASTINUM NOS Highest non-met organ/tissue Other respiratory

165 OTH/ILL-DEF MAL NEO RESP 

165.0 MALIG NEO UPPER RESP NOS Lung Other respiratory

165.8 MALIG NEO THORAX/RESP NEC Lung Other respiratory

165.9 MALIG NEO RESP SYSTEM NOS Lung Other respiratory

170 MALIG NEO BONE/ARTIC CART 

170.0 MALIG NEO SKULL/FACE BONE Bone surface Bone

170.1 MALIG NEO MANDIBLE Bone surface Bone

170.2 MALIG NEO VERTEBRAE Bone surface Bone

170.3 MALIG NEO RIBS/STERN/CLAV Medical review Bone

170.4 MALIG NEO LONG BONES ARM Bone surface Bone

170.5 MALIG NEO BONES WRIST/HAND Bone surface Bone

170.6 MALIG NEO PELVIC GIRDLE Medical review Bone

170.7 MALIG NEO LONG BONES LEG Medical review Bone

170.8 MALIG NEO BONES ANKLE/FOOT Bone surface Bone

170.9 MALIG NEO BONE NOS Medical review Bone

171 MALIG NEO SOFT TISSUE 

171.0 MALIG NEO SOFT TISSUE HEAD Highest non-met organ/tissue Connective Tissue

171.2 MALIG NEO SOFT TISSUE ARM Highest non-met organ/tissue Connective Tissue

171.3 MALIG NEO SOFT TISSUE LEG Highest non-met organ/tissue Connective Tissue

171.4 MALIG NEO SOFT TIS THORAX Highest non-met organ/tissue Connective Tissue

171.5 MALIG NEO SOFT TIS ABDOMEN Highest non-met organ/tissue Connective Tissue

171.6 MALIG NEO SOFT TIS PELVIS Highest non-met organ/tissue Connective Tissue

171.7 MALIG NEO TRUNK NOS Highest non-met organ/tissue Connective Tissue

171.8 MALIG NEO SOFT TISSUE NEC Highest non-met organ/tissue Connective Tissue

171.9 MALIG NEO SOFT TISSUE NOS Highest non-met organ/tissue Connective Tissue
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 7 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

172 MALIGNANT MELANOMA SKIN 

172.0 MALIG MELANOMA LIP Skin Malignant melanoma

172.1 MALIG MELANOMA EYELID Skin Malignant melanoma

172.2 MALIG MELANOMA EAR Skin Malignant melanoma

172.3 MALIG MELANOMA FACE NEC/NOS Skin Malignant melanoma

172.4 MALIG MELANOMA SCALP/NECK Skin Malignant melanoma

172.5 MALIG MELANOMA TRUNK Skin Malignant melanoma

172.6 MALIG MELANOMA ARM Skin Malignant melanoma

172.7 MALIG MELANOMA LEG Skin Malignant melanoma

172.8 MALIG MELANOMA SKIN NEC Skin Malignant melanoma

172.9 MALIG MELANOMA SKIN NOS Skin Malignant melanoma

173 OTHER MALIG NEOPL SKIN 

173.0 MALIG NEO SKIN LIP Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.1 MALIG NEO SKIN EYELID Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.2 MALIG NEO SKIN EAR Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.3 MALIG NEO SKIN FACE NEC Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.4 MALIG NEO SCALP/SKIN NECK Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.5 MALIG NEO SKIN TRUNK Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.6 MALIG NEO SKIN ARM Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.7 MALIG NEO SKIN LEG Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.8 MALIG NEO SKIN NEC Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

173.9 MALIG NEO SKIN NOS Skin

Non-melanoma skin-Basal cell OR

Non-melanoma skin-Squamous cell

174 MALIG NEO FEMALE BREAST 

174.0 MALIG NEO NIPPLE Breast Breast

174.1 MALIG NEO BREAST-CENTRAL Breast Breast

174.2 MALIG NEO BREAST UP-INNER Breast Breast

174.3 MALIG NEO BREAST LOW-INNER Breast Breast

174.4 MALIG NEO BREAST UP-OUTER Breast Breast

174.5 MALIG NEO BREAST LOW-OUTER Breast Breast

174.6 MALIG NEO BREAST-AXILLARY Breast Breast

174.8 MALIG NEO BREAST NEC Breast Breast

174.9 MALIG NEO BREAST NOS Breast Breast

175 MALIG NEO MALE BREAST 

175.0 MALIG NEO MALE NIPPLE Breast Breast

175.9 MALIG NEO MALE BREAST NEC Breast Breast
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 8 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

176 KAPOSI'S SARCOMA

176.0 SKIN-KAPOSI'S SARCOMA Skin

Connective tissue AND

Non-melanoma skin-Squamous cell

176.1 SOFT TISSUE-KAPOSI'S SARCOMA

Highest non-met 

organ/tissue

Connective tissue AND

Non-melanoma skin-Squamous cell

176.2 PALATE-KAPOSI'S SARCOMA

Highest non-met 

organ/tissue

Connective tissue AND

Non-melanoma skin-Squamous cell

176.3 GI SITES-KAPOSI'S SARCOMA Colon

Connective tissue AND

Non-melanoma skin-Squamous cell

176.4 LUNG-KAPOSI'S SARCOMA Lung

Connective tissue AND

Non-melanoma skin-Squamous cell

176.5 LYMPH NODES-KAPOSI'S SARCOMA

Highest non-met 

organ/tissue

Connective tissue AND

Non-melanoma skin-Squamous cell

176.8 SPF STS-KAPOSI'S SARCOMA

Highest non-met 

organ/tissue

Connective tissue AND

Non-melanoma skin-Squamous cell

176.9 KAPOSI'S SARCOMA NOS

Highest non-met 

organ/tissue

Connective tissue AND

Non-melanoma skin-Squamous cell

179 MALIG NEO UTERUS NOS Uterus Female genitalia less ovary

180 MALIG NEO CERVIX UTERI 

180.0 MALIG NEO ENDOCERVIX Uterus Female genitalia less ovary

180.1 MALIG NEO EXOCERVIX Uterus Female genitalia less ovary

180.8 MALIG NEO CERVIX NEC Uterus Female genitalia less ovary

180.9 MALIG NEO CERVIX UTERI NOS Uterus Female genitalia less ovary

181 MALIG NEO PLACENTA Uterus Female genitalia less ovary

182 MALIG NEO UTERUS BODY 

182.0 MALIG NEO CORPUS UTERI Uterus Female genitalia less ovary

182.1 MALIG NEO UTERINE ISTHMUS Uterus Female genitalia less ovary

182.8 MALIG NEO BODY UTERUS NEC Uterus Female genitalia less ovary

183 MALIG NEO UTERINE ADNEXA 

183.0 MALIG NEO OVARY Ovaries Ovary

183.2 MALIG NEO FALLOPIAN TUBE Ovaries Ovary

183.3 MALIG NEO BROAD LIGAMENT Ovaries Ovary

183.4 MALIG NEO PARAMETRIUM Uterus Ovary

183.5 MALIG NEO ROUND LIGAMENT Uterus Ovary

183.8 MALIG NEO ADNEXA NEC Ovaries Ovary

183.9 MALIG NEO ADNEXA NOS Ovaries Ovary

184 MALIG NEO FEM GEN NEC/NOS 

184.0 MALIG NEO VAGINA Muscle Female genitalia less ovary

184.1 MALIG NEO LABIA MAJORA Skin Female genitalia less ovary

184.2 MALIG NEO LABIA MINORA Skin Female genitalia less ovary

184.3 MALIG NEO CLITORIS Skin Female genitalia less ovary

184.4 MALIG NEO VULVA NOS Skin Female genitalia less ovary

184.8 MALIG NEO FEMALE GENIT NEC Uterus Female genitalia less ovary

184.9 MALIG NEO FEMALE GENIT NOS Uterus Female genitalia less ovary

185 MALIG NEO PROSTATE 

Highest non-met 

organ/tissue All male genitalia
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 9 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

186 MALIG NEO TESTIS 

186.0 MALIG NEO UNDESCEND TESTIS Testes All male genitalia

186.9 MALIG NEO TESTIS NEC Testes All male genitalia

187 MALIG NEO MALE GENITAL NEC 

187.1 MALIG NEO PREPUCE Skin All male genitalia

187.2 MALIG NEO GLANS PENIS Skin All male genitalia

187.3 MALIG NEO PENIS BODY Testes All male genitalia

187.4 MALIG NEO PENIS NOS Testes All male genitalia

187.5 MALIG NEO EPIDIDYMIS Testes All male genitalia

187.6 MALIG NEO SPERMATIC CORD Testes All male genitalia

187.7 MALIG NEO SCROTUM Testes All male genitalia

187.8 MALIG NEO MALE GENITAL NEC Testes All male genitalia

187.9 MALIG NEO MALE GENITAL NOS Testes All male genitalia

188 MALIG NEO BLADDER 

188.0 MALIG NEO BLADDER-TRIGONE Bladder Bladder

188.1 MALIG NEO BLADDER-DOME Bladder Bladder

188.2 MALIG NEO BLADDER-LATERAL Bladder Bladder

188.3 MALIG NEO BLADDER-ANTERIOR Bladder Bladder

188.4 MALIG NEO BLADDER-POST Bladder Bladder

188.5 MALIG NEO BLADDER NECK Bladder Bladder

188.6 MALIG NEO URETERIC ORIFICE Bladder Bladder

188.7 MALIG NEO URACHUS Bladder Bladder

188.8 MALIG NEO BLADDER NEC Bladder Bladder

188.9 MALIG NEO BLADDER NOS Bladder Bladder

189 MALIG NEO URINARY NEC/NOS 

189.0 MALIG NEO KIDNEY Kidney Urinary organs less bladder

189.1 MALIG NEO RENAL PELVIS Kidney Urinary organs less bladder

189.2 MALIG NEO URETER Kidney Urinary organs less bladder

189.3 MALIG NEO URETHRA Bladder Urinary organs less bladder

189.4 MALIG NEO PARAURETHRAL Bladder Urinary organs less bladder

189.8 MALIG NEO URINARY NEC Bladder Urinary organs less bladder

189.9 MALIG NEO URINARY NOS Medical review Urinary organs less bladder

190 MALIGANT NEOPLASM EYE 

190.0 MALIG NEO EYEBALL Brain Eye

190.1 MALIG NEO ORBIT Brain Eye

190.2 MALIG NEO LACRIMAL GLAND Skin Eye

190.3 MALIG NEO CONJUNCTIVA Skin Eye

190.4 MALIG NEO CORNEA Skin Eye

190.5 MALIG NEO RETINA Brain Eye

190.6 MALIG NEO CHOROID Brain Eye

190.7 MALIG NEO LACRIMAL DUCT Skin Eye

190.8 MALIG NEO EYE NEC Skin Eye

190.9 MALIG NEO EYE NOS Skin Eye
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 10 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

191 MALIG NEOASM BRAIN 

191.0 MALIG NEO CEREBRUM Brain Nervous system

191.1 MALIG NEO FRONTAL LOBE Brain Nervous system

191.2 MALIG NEO TEMPORAL LOBE Brain Nervous system

191.3 MALIG NEO PARIETAL LOBE Brain Nervous system

191.4 MALIG NEO OCCIPITAL LOBE Brain Nervous system

191.5 MALIG NEO CEREB VENTRICLE Brain Nervous system

191.6 MALIG NEO CEREBELLUM NOS Brain Nervous system

191.7 MALIG NEO BRAIN STEM Brain Nervous system

191.8 MALIG NEO BRAIN NEC Brain Nervous system

191.9 MALIG NEO BRAIN NOS Brain Nervous system

192 MALIG NEO NERVE NEC/NOS 

192.0 MALIG NEO CRANIAL NERVES Brain Nervous system

192.1 MALIG NEO CEREBRAL MENING Brain Nervous system

192.2 MALIG NEO SPINAL CORD Brain Nervous system

192.3 MALIG NEO SPINAL MENINGES Brain Nervous system

192.8 MALIG NEO NERVOUS SYST NEC Brain Nervous system

192.9 MALIG NEO NERVOUS SYST NOS Brain Nervous system

193 MALIG NEO THYROID Thyroid Thyroid

194 MALIG NEO OTHER ENDOCRINE Medical review Other endocrine glands

194.0 MALIG NEO ADRENAL Adrenals Other endocrine glands

194.1 MALIG NEO PARATHYROID Thyroid Other endocrine glands

194.3 MALIG NEO PITUITARY Brain Other endocrine glands

194.4 MALIG NEO PINEAL GLAND Brain Other endocrine glands

194.5 MALIG NEO CAROTID BODY Brain Other endocrine glands

194.6 MALIG NEO PARAGANGLIA NEC Brain Other endocrine glands

194.8 MALIG NEO ENDOCRINE NEC Medical review Other endocrine glands

194.9 MALIG NEO ENDOCRINE NOS Medical review Other endocrine glands

195 MALIG NEO OTH/ILL-DEF SITE 

195.0 MALIG NEO HEAD/FACE/NECK Highest non-met organ/tissue Other and ill-defined sites

195.1 MALIG NEO THORAX Highest non-met organ/tissue Other and ill-defined sites

195.2 MALIG NEO ABDOMEN Highest non-met organ/tissue Other and ill-defined sites

195.3 MALIG NEO PELVIS Highest non-met organ/tissue Other and ill-defined sites

195.4 MALIG NEO ARM Highest non-met organ/tissue Other and ill-defined sites

195.5 MALIG NEO LEG Highest non-met organ/tissue Other and ill-defined sites

195.8 MALIG NEO SITE NEC Highest non-met organ/tissue Other and ill-defined sites

196 MALIG NEO LYMPH NODES

196.0 MALIG NEO LYMPH-HEAD/NECK Do not do - secondary NA

196.1 MALIG NEO LYMPH-INTRATHOR Do not do - secondary NA

196.2 MALIG NEO LYMPH-INTRA-ABD Do not do - secondary NA

196.3 MALIG NEO LYMPH-AXILLA/ARM Do not do - secondary NA

196.5 MALIG NEO LYMPH-INGUIN/LEG Do not do - secondary NA

196.6 MALIG NEO LYMPH-INTRAPELV Do not do - secondary NA

196.8 MALIG NEO LYMPH-MULT Do not do - secondary NA

196.9 MALIG NEO LYMPH NOS Do not do - secondary NA
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 11 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

197 SEC MALIG NEO GI/RESP

197.0 SEC MALIG NEO LUNG Do not do - secondary NA

197.1 SEC MALIG NEO MEDIASTINUM Do not do - secondary NA

197.2 SEC MALIG NEO PLEURA Do not do - secondary NA

197.3 SEC MALIG NEO RESP NEC Do not do - secondary NA

197.4 SEC MALIG NEO SM BOWEL Do not do - secondary NA

197.5 SEC MALIG NEO LG BOWEL Do not do - secondary NA

197.6 SEC MALIG NEO PERITONEUM Do not do - secondary NA

197.7 SEC MALIG NEO LIVER Do not do - secondary NA

197.8 SEC MALIG NEO GI NEC Do not do - secondary NA

198 SEC MALIG NEO OTHER SITES

198.0 SEC MALIG NEO KIDNEY Do not do - secondary NA

198.1 SEC MALIG NEO URIN NEC Do not do - secondary NA

198.2 SEC MALIG NEO SKIN Do not do - secondary NA

198.3 SEC MALIG NEO BRAIN/SPINE Do not do - secondary NA

198.4 SEC MALIG NEO NERVE NEC Do not do - secondary NA

198.5 SEC MALIG NEO BONE Do not do - secondary NA

198.6 SEC MALIG NEO OVARY Do not do - secondary NA

198.7 SEC MALIG NEO ADRENAL Do not do - secondary NA

198.8 OTHER SECONDARY MALIG NEO 

198.81 SEC MALIG NEO BREAST Do not do - secondary NA

198.82 SEC MALIG NEO GENITAL Do not do - secondary NA

198.89 SEC MALIG NEO NEC Do not do - secondary NA

199 MALIG NEOPLASM NOS

199.0 MALIG NEO DISSEMINATED

Highest non-met 

organ/tissue Other and ill-defined sites

199.1 MALIG NEO NOS

Highest non-met 

organ/tissue Other and ill-defined sites

200 LYMPHOSARC/RETICULOSARC 

200.0 RETICULOSARCOMA Medical review Lymphoma and multiple myeloma

200.00 RETCLSRC UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

200.01 RETICULOSARCOMA HEAD Medical review Lymphoma and multiple myeloma

200.02 RETICULOSARCOMA THORAX Medical review Lymphoma and multiple myeloma

200.03 RETICULOSARCOMA ABDOM Medical review Lymphoma and multiple myeloma

200.04 RETICULOSARCOMA AXILLA Medical review Lymphoma and multiple myeloma

200.05 RETICULOSARCOMA INGUIN Medical review Lymphoma and multiple myeloma

200.06 RETICULOSARCOMA PELVIC Medical review Lymphoma and multiple myeloma

200.07 RETICULOSARCOMA SPLEEN Medical review Lymphoma and multiple myeloma

200.08 RETICULOSARCOMA MULT Medical review Lymphoma and multiple myeloma

200.1 LYMPHOSARCOMA Medical review Lymphoma and multiple myeloma

200.10 LYMPHSRC UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

200.11 LYMPHOSARCOMA HEAD Medical review Lymphoma and multiple myeloma

200.12 LYMPHOSARCOMA THORAX Medical review Lymphoma and multiple myeloma

200.13 LYMPHOSARCOMA ABDOM Medical review Lymphoma and multiple myeloma

200.14 LYMPHOSARCOMA AXILLA Medical review Lymphoma and multiple myeloma

200.15 LYMPHOSARCOMA INGUIN Medical review Lymphoma and multiple myeloma

200.16 LYMPHOSARCOMA PELVIC Medical review Lymphoma and multiple myeloma

200.17 LYMPHOSARCOMA SPLEEN Medical review Lymphoma and multiple myeloma

200.18 LYMPHOSARCOMA MULT Medical review Lymphoma and multiple myeloma
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 12 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

200.2 BURKITT'S TUMOR/LYMPHOMA Medical review Lymphoma and multiple myeloma

200.20

 BURKITT'S TUMOR UNSPEC EXT 

ORG Medical review Lymphoma and multiple myeloma

200.21 BURKITT'S TUMOR HEAD Medical review Lymphoma and multiple myeloma

200.22 BURKITT'S TUMOR THORAX Medical review Lymphoma and multiple myeloma

200.23 BURKITT'S TUMOR ABDOM Medical review Lymphoma and multiple myeloma

200.24 BURKITT'S TUMOR AXILLA Medical review Lymphoma and multiple myeloma

200.25 BURKITT'S TUMOR INGUIN Medical review Lymphoma and multiple myeloma

200.26 BURKITT'S TUMOR PELVIC Medical review Lymphoma and multiple myeloma

200.27 BURKITT'S TUMOR SPLEEN Medical review Lymphoma and multiple myeloma

200.28 BURKITT'S TUMOR MULT Medical review Lymphoma and multiple myeloma

200.8 MIXED LYMPHOSARCOMA Medical review Lymphoma and multiple myeloma

200.80 OTHER VARN UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

200.81 MIXED LYMPHOSARC HEAD Medical review Lymphoma and multiple myeloma

200.82 MIXED LYMPHOSARC THORAX Medical review Lymphoma and multiple myeloma

200.83 MIXED LYMPHOSARC ABDOM Medical review Lymphoma and multiple myeloma

200.84 MIXED LYMPHOSARC AXILLA Medical review Lymphoma and multiple myeloma

200.85 MIXED LYMPHOSARC INGUIN Medical review Lymphoma and multiple myeloma

200.86 MIXED LYMPHOSARC PELVIC Medical review Lymphoma and multiple myeloma

200.87 MIXED LYMPHOSARC SPLEEN Medical review Lymphoma and multiple myeloma

200.88 MIXED LYMPHOSARC MULT Medical review Lymphoma and multiple myeloma

201 HODGKIN'S DISEASE 

201.0 HODGKIN'S PARAGRANULOMA Medical review Lymphoma and multiple myeloma

201.00

 HODGKINS PARAGRANULOMA 

 UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

201.01 HODGKINS PARAGRAN HEAD Medical review Lymphoma and multiple myeloma

201.02 HODGKINS PARAGRAN THORAX Medical review Lymphoma and multiple myeloma

201.03 HODGKINS PARAGRAN ABDOM Medical review Lymphoma and multiple myeloma

201.04 HODGKINS PARAGRAN AXILLA Medical review Lymphoma and multiple myeloma

201.05 HODGKINS PARAGRAN INGUIN Medical review Lymphoma and multiple myeloma

201.06 HODGKINS PARAGRAN PELVIC Medical review Lymphoma and multiple myeloma

201.07 HODGKINS PARAGRAN SPLEEN Medical review Lymphoma and multiple myeloma

201.08 HODGKINS PARAGRAN MULT Medical review Lymphoma and multiple myeloma

201.1 HODGKIN'S GRANULOMA Medical review Lymphoma and multiple myeloma

201.10

 HODGKINS GRANULOM UNSPEC 

EXT ORG Medical review Lymphoma and multiple myeloma

201.11 HODGKINS GRANULOM HEAD Medical review Lymphoma and multiple myeloma

201.12 HODGKINS GRANULOM THORAX Medical review Lymphoma and multiple myeloma

201.13 HODGKINS GRANULOM ABDOM Medical review Lymphoma and multiple myeloma

201.14 HODGKINS GRANULOM AXILLA Medical review Lymphoma and multiple myeloma

201.15 HODGKINS GRANULOM INGUIN Medical review Lymphoma and multiple myeloma

201.16 HODGKINS GRANULOM PELVIC Medical review Lymphoma and multiple myeloma

201.17 HODGKINS GRANULOM SPLEEN Medical review Lymphoma and multiple myeloma

201.18 HODGKINS GRANULOM MULT Medical review Lymphoma and multiple myeloma
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 13 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

201.2 HODGKIN'S SARCOMA Medical review Lymphoma and multiple myeloma

201.20 HODGKINS SRC UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

201.21 HODGKINS SARCOMA HEAD Medical review Lymphoma and multiple myeloma

201.22 HODGKINS SARCOMA THORAX Medical review Lymphoma and multiple myeloma

201.23 HODGKINS SARCOMA ABDOM Medical review Lymphoma and multiple myeloma

201.24 HODGKINS SARCOMA AXILLA Medical review Lymphoma and multiple myeloma

201.25 HODGKINS SARCOMA INGUIN Medical review Lymphoma and multiple myeloma

201.26 HODGKINS SARCOMA PELVIC Medical review Lymphoma and multiple myeloma

201.27 HODGKINS SARCOMA SPLEEN Medical review Lymphoma and multiple myeloma

201.28 HODGKINS SARCOMA MULT Medical review Lymphoma and multiple myeloma

201.4 HODGKINS LYMPH-HISTIOCYT Medical review Lymphoma and multiple myeloma

201.40 LYM-HST UNSPEC EXT ORGN Medical review Lymphoma and multiple myeloma

201.41 HODGKINS LYMPH-HISTIO HEAD Medical review Lymphoma and multiple myeloma

201.42 HODGKINS LYMPH-HISTIO THORAX Medical review Lymphoma and multiple myeloma

201.43 HODGKINS LYMPH-HISTIO ABDOM Medical review Lymphoma and multiple myeloma

201.44 HODGKINS LYMPH-HISTIO AXILLA Medical review Lymphoma and multiple myeloma

201.45 HODGKINS LYMPH-HISTIO INGUIN Medical review Lymphoma and multiple myeloma

201.46 HODGKINS LYMPH-HISTIO PELVIC Medical review Lymphoma and multiple myeloma

201.47 HODGKINS LYMPH-HISTIO SPLEEN Medical review Lymphoma and multiple myeloma

201.48 HODGKINS LYMPH-HISTIO MULT Medical review Lymphoma and multiple myeloma

201.5 HODGKINS NODULAR SCLEROS Medical review Lymphoma and multiple myeloma

201.50

 NODULAR SCLEROS UNSPEC EXT 

ORG Medical review Lymphoma and multiple myeloma

201.51 HODGKINS NODUL SCLERO HEAD Medical review Lymphoma and multiple myeloma

201.52 HODGKINS NODUL SCLERO THORAX Medical review Lymphoma and multiple myeloma

201.53 HODGKINS NODUL SCLERO ABDOM Medical review Lymphoma and multiple myeloma

201.54 HODGKINS NODUL SCLERO AXILLA Medical review Lymphoma and multiple myeloma

201.55 HODGKINS NODUL SCLERO INGUIN Medical review Lymphoma and multiple myeloma

201.56 HODGKINS NODUL SCLERO PELVIC Medical review Lymphoma and multiple myeloma

201.57 HODGKINS NODUL SCLERO SPLEEN Medical review Lymphoma and multiple myeloma

201.58 HODGKINS NODUL SCLERO MULT Medical review Lymphoma and multiple myeloma

201.6 HODGKINS MIX CELLULARITY Medical review Lymphoma and multiple myeloma

201.60 MXD CELR UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

201.61 HODGKINS MIX CELL HEAD Medical review Lymphoma and multiple myeloma

201.62 HODGKINS MIX CELL THORAX Medical review Lymphoma and multiple myeloma

201.63 HODGKINS MIX CELL ABDOM Medical review Lymphoma and multiple myeloma

201.64 HODGKINS MIX CELL AXILLA Medical review Lymphoma and multiple myeloma

201.65 HODGKINS MIX CELL INGUIN Medical review Lymphoma and multiple myeloma

201.66 HODGKINS MIX CELL PELVIC Medical review Lymphoma and multiple myeloma

201.67 HODGKINS MIX CELL SPLEEN Medical review Lymphoma and multiple myeloma

201.68 HODGKINS MIX CELL MULT Medical review Lymphoma and multiple myeloma
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 14 of 24

Table 1 (cont)

ICD-9 

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

201.7 HODG LYMPHOCYTIC DEPLET Medical review Lymphoma and multiple myeloma

201.70 LYM DPLT UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

201.71 HODGKINS LYMPH DEPLET HEAD Medical review Lymphoma and multiple myeloma

201.72 HODGKINS LYMPH DEPLET THORAX Medical review Lymphoma and multiple myeloma

201.73 HODGKINS LYMPH DEPLET ABDOM Medical review Lymphoma and multiple myeloma

201.74 HODGKINS LYMPH DEPLET AXILLA Medical review Lymphoma and multiple myeloma

201.75 HODGKINS LYMPH DEPLET INGUIN Medical review Lymphoma and multiple myeloma

201.76 HODGKINS LYMPH DEPLET PELVIC Medical review Lymphoma and multiple myeloma

201.77 HODGKINS LYMPH DEPLET SPLEEN Medical review Lymphoma and multiple myeloma

201.78 HODGKINS LYMPH DEPLET MULT Medical review Lymphoma and multiple myeloma

201.9 HODGKINS DISEASE NOS Medical review Lymphoma and multiple myeloma

201.90 HDGK DISEASE UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

201.91 HODGKINS DISEASE NOS HEAD Medical review Lymphoma and multiple myeloma

201.92 HODGKINS DISEASE NOS THORAX Medical review Lymphoma and multiple myeloma

201.93 HODGKINS DISEASE NOS ABDOM Medical review Lymphoma and multiple myeloma

201.94 HODGKINS DISEASE NOS AXILLA Medical review Lymphoma and multiple myeloma

201.95 HODGKINS DISEASE NOS INGUIN Medical review Lymphoma and multiple myeloma

201.96 HODGKINS DISEASE NOS PELVIC Medical review Lymphoma and multiple myeloma

201.97 HODGKINS DISEASE NOS SPLEEN Medical review Lymphoma and multiple myeloma

201.98 HODGKINS DISEASE NOS MULT Medical review Lymphoma and multiple myeloma

202 OTHER MALIG NEO LYMPH/HISTIO 

202.0 NODULAR LYMPHOMA Medical review Lymphoma and multiple myeloma

202.00 NDLR LYM UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.01 NODULAR LYMPHOMA HEAD Medical review Lymphoma and multiple myeloma

202.02 NODULAR LYMPHOMA THORAX Medical review Lymphoma and multiple myeloma

202.03 NODULAR LYMPHOMA ABDOM Medical review Lymphoma and multiple myeloma

202.04 NODULAR LYMPHOMA AXILLA Medical review Lymphoma and multiple myeloma

202.05 NODULAR LYMPHOMA INGUIN Medical review Lymphoma and multiple myeloma

202.06 NODULAR LYMPHOMA PELVIC Medical review Lymphoma and multiple myeloma

202.07 NODULAR LYMPHOMA SPLEEN Medical review Lymphoma and multiple myeloma

202.08 NODULAR LYMPHOMA MULT Medical review Lymphoma and multiple myeloma

202.1 MYCOSIS FUNGOIDES Medical review Lymphoma and multiple myeloma

202.10 MYCS FNG UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.11 MYCOSIS FUNGOIDES HEAD Medical review Lymphoma and multiple myeloma

202.12 MYCOSIS FUNGOIDES THORAX Medical review Lymphoma and multiple myeloma

202.13 MYCOSIS FUNGOIDES ABDOM Medical review Lymphoma and multiple myeloma

202.14 MYCOSIS FUNGOIDES AXILLA Medical review Lymphoma and multiple myeloma

202.15 MYCOSIS FUNGOIDES INGUIN Medical review Lymphoma and multiple myeloma

202.16 MYCOSIS FUNGOIDES PELVIC Medical review Lymphoma and multiple myeloma

202.17 MYCOSIS FUNGOIDES SPLEEN Medical review Lymphoma and multiple myeloma

202.18 MYCOSIS FUNGOIDES MULT Medical review Lymphoma and multiple myeloma
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 15 of 24

Table 1 (cont)

ICD-9 

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

202.2 SEZARY'S DISEASE Medical review Lymphoma and multiple myeloma

202.20 SZRY DISEASE UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.21 SEZARY'S DISEASE HEAD Medical review Lymphoma and multiple myeloma

202.22 SEZARY'S DISEASE THORAX Medical review Lymphoma and multiple myeloma

202.23 SEZARY'S DISEASE ABDOM Medical review Lymphoma and multiple myeloma

202.24 SEZARY'S DISEASE AXILLA Medical review Lymphoma and multiple myeloma

202.25 SEZARY'S DISEASE INGUIN Medical review Lymphoma and multiple myeloma

202.26 SEZARY'S DISEASE PELVIC Medical review Lymphoma and multiple myeloma

202.27 SEZARY'S DISEASE SPLEEN Medical review Lymphoma and multiple myeloma

202.28 SEZARY'S DISEASE MULT Medical review Lymphoma and multiple myeloma

202.3 MALIG HISTIOCYTOSIS Medical review Lymphoma and multiple myeloma

202.30 MLG HIST UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.31 MALIG HISTIOCYTOSIS HEAD Medical review Lymphoma and multiple myeloma

202.32 MALIG HISTIOCYTOSIS THORAX Medical review Lymphoma and multiple myeloma

202.33 MALIG HISTIOCYTOSIS ABDOM Medical review Lymphoma and multiple myeloma

202.34 MALIG HISTIOCYTOSIS AXILLA Medical review Lymphoma and multiple myeloma

202.35 MALIG HISTIOCYTOSIS INGUIN Medical review Lymphoma and multiple myeloma

202.36 MALIG HISTIOCYTOSIS PELVIC Medical review Lymphoma and multiple myeloma

202.37 MALIG HISTIOCYTOSIS SPLEEN Medical review Lymphoma and multiple myeloma

202.38 MALIG HISTIOCYTOSIS MULT Medical review Lymphoma and multiple myeloma

202.4 LEUKEM RETICULOENDOTHEL Medical review Lymphoma and multiple myeloma

202.40 LK RTCTL UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.41 HAIRY-CELL LEUKEM HEAD Medical review Lymphoma and multiple myeloma

202.42 HAIRY-CELL LEUKEM THORAX Medical review Lymphoma and multiple myeloma

202.43 HAIRY-CELL LEUKEM ABDOM Medical review Lymphoma and multiple myeloma

202.44 HAIRY-CELL LEUKEM AXILLA Medical review Lymphoma and multiple myeloma

202.45 HAIRY-CELL LEUKEM INGUIN Medical review Lymphoma and multiple myeloma

202.46 HAIRY-CELL LEUKEM PELVIC Medical review Lymphoma and multiple myeloma

202.47 HAIRY-CELL LEUKEM SPLEEN Medical review Lymphoma and multiple myeloma

202.48 HAIRY-CELL LEUKEM MULT Medical review Lymphoma and multiple myeloma

202.5 LETTERER-SIWE DISEASE Medical review Lymphoma and multiple myeloma

202.50 LTR-SIWE UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.51 LETTERER-SIWE DISEASE HEAD Medical review Lymphoma and multiple myeloma

202.52 LETTERER-SIWE DISEASE THORAX Medical review Lymphoma and multiple myeloma

202.53 LETTERER-SIWE DISEASE ABDOM Medical review Lymphoma and multiple myeloma

202.54 LETTERER-SIWE DISEASE AXILLA Medical review Lymphoma and multiple myeloma

202.55 LETTERER-SIWE DISEASE INGUIN Medical review Lymphoma and multiple myeloma

202.56 LETTERER-SIWE DISEASE PELVIC Medical review Lymphoma and multiple myeloma

202.57 LETTERER-SIWE DISEASE SPLEEN Medical review Lymphoma and multiple myeloma

202.58 LETTERER-SIWE DISEASE MULT Medical review Lymphoma and multiple myeloma

202.6 MALIG MAST CELL TUMORS Medical review Lymphoma and multiple myeloma

202.60 MALIG MAST UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.61 MALIG MASTOCYTOSIS HEAD Medical review Lymphoma and multiple myeloma

202.62 MALIG MASTOCYTOSIS THORAX Medical review Lymphoma and multiple myeloma

202.63 MALIG MASTOCYTOSIS ABDOM Medical review Lymphoma and multiple myeloma

202.64 MALIG MASTOCYTOSIS AXILLA Medical review Lymphoma and multiple myeloma

202.65 MALIG MASTOCYTOSIS INGUIN Medical review Lymphoma and multiple myeloma

202.66 MALIG MASTOCYTOSIS PELVIC Medical review Lymphoma and multiple myeloma

202.67 MALIG MASTOCYTOSIS SPLEEN Medical review Lymphoma and multiple myeloma

202.68 MALIG MASTOCYTOSIS MULT Medical review Lymphoma and multiple myeloma
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 16 of 24

Table 1 (cont)

ICD-9 

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

202.8 LYMPHOMAS NEC Medical review Lymphoma and multiple myeloma

202.80 OTHER LYMP UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.81 LYMPHOMAS NEC HEAD Medical review Lymphoma and multiple myeloma

202.82 LYMPHOMAS NEC THORAX Medical review Lymphoma and multiple myeloma

202.83 LYMPHOMAS NEC ABDOM Medical review Lymphoma and multiple myeloma

202.84 LYMPHOMAS NEC AXILLA Medical review Lymphoma and multiple myeloma

202.85 LYMPHOMAS NEC INGUIN Medical review Lymphoma and multiple myeloma

202.86 LYMPHOMAS NEC PELVIC Medical review Lymphoma and multiple myeloma

202.87 LYMPHOMAS NEC SPLEEN Medical review Lymphoma and multiple myeloma

202.88 LYMPHOMAS NEC MULT Medical review Lymphoma and multiple myeloma

202.9 MALIG NEO LYM/HIST TIS NEC Medical review Lymphoma and multiple myeloma

202.90 UNSPEC LYM UNSPEC EXT ORG Medical review Lymphoma and multiple myeloma

202.91 LYMPHOID MALIG NEC HEAD Medical review Lymphoma and multiple myeloma

202.92 LYMPHOID MALIG NEC THORAX Medical review Lymphoma and multiple myeloma

202.93 LYMPHOID MALIG NEC ABDOM Medical review Lymphoma and multiple myeloma

202.94 LYMPHOID MALIG NEC AXILLA Medical review Lymphoma and multiple myeloma

202.95 LYMPHOID MALIG NEC INGUIN Medical review Lymphoma and multiple myeloma

202.96 LYMPHOID MALIG NEC PELVIC Medical review Lymphoma and multiple myeloma

202.97 LYMPHOID MALIG NEC SPLEEN Medical review Lymphoma and multiple myeloma

202.98 LYMPHOID MALIG NEC MULT Medical review Lymphoma and multiple myeloma

203 MULTIPLE MYELOMA ET AL 

203.0 MULTIPLE MYELOMA 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.00 MULT MYELM W/O REMISSION 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.01 MULT MYELM W/REMISSION 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.1 PLASMA CELL LEUKEMIA 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.10 PLSM CELL LEUK W/O REMISSON 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.11 PLSM CELL LEUK W/REMISS 

Red Bone 

Marrow Lymphoma and multiple myeloma

203.8 IMMUNOPROLIFERAT NEOPLASM NEC Medical review Lymphoma and multiple myeloma

203.80 OTHER IMNPRFL NPL W/O REMISS Medical review Lymphoma and multiple myeloma

203.81 OTHER IMNPRFL NPL W/REMISS Medical review Lymphoma and multiple myeloma

204 LYMPHOID LEUKEMIA 

204.0 ACUTE LYMPHOID LEUKEMIA Medical review Acute lymphoid leukemia

204.00 ACT LYM LEUK W/O REMISS Medical review Acute lymphoid leukemia

204.01 ACT LYM LEUK W/REMISS Medical review Acute lymphoid leukemia

204.1 CHRONIC LYMPHOID LEUKEMIA NA

42 CFR 81.30 states this cancer is

non-radiogenic for the purposes of 

EEOICPA and assigns zero 

probability of causation.

204.10

 CHRONIC LYM LEUK W/O 

REMISSION NA

42 CFR 81.30 states this cancer is

non-radiogenic for the purposes of 

EEOICPA and assigns zero 

probability of causation.

204.11 CHRONIC LYM LEUK W/REMISSION NA

42 CFR 81.30 states this cancer is

non-radiogenic for the purposes of 

EEOICPA and assigns zero 

probability of causation.
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 17 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

204.2 SUBACUTE LYMPHOID LEUKEMIA Medical review Leukemia, less CLL

204.20 SBAC LYM LEUK W/O REMISS Medical review Leukemia, less CLL

204.21 SBAC LYM LEUK W/REMISS Medical review Leukemia, less CLL

204.8 LYMPHOID LEUKEMIA NEC Medical review Leukemia, less CLL

204.80 OTHER LYM LEUK W/O REMISS Medical review Leukemia, less CLL

204.81 OTHER LYM LEUK W/REMISS Medical review Leukemia, less CLL

204.9 LYMPHOID LEUKEMIA NOS Medical review Acute lymphoid leukemia

204.90 UNS LYM LEUK W/O REMISS Medical review Acute lymphoid leukemia

204.91 UNS LYM LEUK W/REMISS Medical review Acute lymphoid leukemia

205 MYELOID LEUKEMIA 

205.0 ACUTE MYELOID LEUKEMIA Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia

205.00 ACT MYL LEUK W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia

205.01 ACT MYL LEUK W/REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia

205.1 CHRONIC MYELOID LEUKEMIA Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

205.10 CHRONIC MYL LEUK W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

205.11 CHRONIC MYL LEUK W/REMISS Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

205.2 SUBACUT MYELOID LEUKEMIA Red Bone Marrow Leukemia, less CLL

205.20 SBAC MYL LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

205.21 SBAC MYL LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

205.3 MYELOID SARCOMA Red Bone Marrow Leukemia, less CLL

205.30 MYL SRCOMA W/O REMISS Red Bone Marrow Leukemia, less CLL

205.31 MYL SRCOMA W/REMISS Red Bone Marrow Leukemia, less CLL

205.8 MYELOID LEUKEMIA NEC Red Bone Marrow Leukemia, less CLL

205.80 OTHER MYL LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

205.81 OTHER MYL LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

205.9 MYELOID LEUKEMIA NOS Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia

205.90 UNS MYL LEUK W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia

205.91 UNS MYL LEUK W/REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute myeloid leukemia
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 18 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

206 MONOCYTIC LEUKEMIA 

206.0 ACUTE MONOCYTIC LEUKEMIA Red Bone Marrow Leukemia, less CLL

206.00 ACT MONO LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

206.01 ACT MONO LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

206.1 CHRONIC MONOCYTIC LEUKEMIA Red Bone Marrow Leukemia, less CLL

206.10 CHRONIC MONO LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

206.11 CHRONIC MONO LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

206.2 SUBAC MONOCYTIC LEUKEMIA Red Bone Marrow Leukemia, less CLL

206.20 SBACUTE MONO LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

206.21 SBACUTE MONO LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

206.8 MONOCYTIC LEUKEMIA NEC Red Bone Marrow Leukemia, less CLL

206.80 OTHER MONO LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

206.81 OTHER MONO LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

206.9 MONOCYTIC LEUKEMIA NOS Red Bone Marrow Leukemia, less CLL

206.90 UNS MONO LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

206.91 UNS MONO LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

207 OTHER SPECIFIED LEUKEMIA 

207.0 ACUTE ERYTHREMIA Red Bone Marrow Leukemia, less CLL

207.00 ACT ERTH/ERYLK W/O REMISS Red Bone Marrow Leukemia, less CLL

207.01 ACT ERTH/ERYLK W/REMISS Red Bone Marrow Leukemia, less CLL

207.1 CHRONIC ERYTHREMIA Red Bone Marrow Leukemia, less CLL

207.10 CHRONIC ERYTHRM W/O REMISION Red Bone Marrow Leukemia, less CLL

207.11 CHRONIC ERYTHRM W/REMISION Red Bone Marrow Leukemia, less CLL

207.2 MEGAKARYOCYTIC LEUKEMIA Red Bone Marrow Leukemia, less CLL

207.20 MGKRYCYT LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

207.21 MGKRYCYT LEUK W/REMISS Red Bone Marrow Leukemia, less CLL

207.8 SPECIFIED LEUKEMIA NEC Red Bone Marrow Leukemia, less CLL

207.80 OTHER SPF LEUK W/O REMISS Red Bone Marrow Leukemia, less CLL

207.81 OTHER SPF LEUK W/REMSION Red Bone Marrow Leukemia, less CLL
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 19 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

208 LEUKEMIA-UNSPECIF CELL 

208.0 ACT LEUK UNS CL W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia

208.00 ACT LEUK UNS CL W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia

208.01 ACT LEUK UNS CL W/REMISS Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia

208.1 CHRONIC LEUKEMIA NOS Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

208.10 CHRONIC LEUK UNS CL W/O REMISS Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

208.11 CHRONIC LEUK UNS CL W/REMISS Red Bone Marrow

Leukemia, less CLL AND

Chronic myeloid leukemia

208.2 SUBACUTE LEUKEMIA NOS Red Bone Marrow Leukemia, less CLL

208.21

 SUBACUTE LEUKEMIA UNS CL 

 W/REMISSION Red Bone Marrow Leukemia, less CLL

208.8 LEUKEMIA-UNSPEC CELL NEC Red Bone Marrow Leukemia, less CLL

208.80 OTHER LEUK UNS CL W/O REMISSION Red Bone Marrow Leukemia, less CLL

208.81 OTHER LEUK UNS CL W/REMISSION Red Bone Marrow Leukemia, less CLL

208.9 LEUKEMIA-UNSPEC CELL NOS Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia AND

Chronic myeloid leukemia

208.90 OTHER LEUK NOS W/O REMISSION Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia AND

Chronic myeloid leukemia

208.91 OTHER LEUK NOS W/REMISSION Red Bone Marrow

Leukemia, less CLL AND

Acute lymphoid leukemia AND

Acute myeloid leukemia AND

Chronic myeloid leukemia

230 CA IN SITU DIGESTIVE ORG 

230.0 CA IN SITU ORAL CAV/PHAR 

Highest non-met 

organ/tissue Oral cav. and pharynx

230.1 CA IN SITU ESOPHAGUS Esophagus Esophagus

230.2 CA IN SITU STOMACH Stomach Stomach

230.3 CA IN SITU COLON Colon Colon

230.4 CA IN SITU RECTUM LLI Rectum

230.5 CA IN SITU ANAL CANAL LLI Rectum

230.6 CA IN SITU ANUS NOS LLI Rectum

230.7 CA IN SITU BOWEL NEC/NOS Colon All digestive

230.8 CA IN SITU LIVER/BILIARY Liver Liver

230.9 CA IN SITU GI NEC/NOS 

Highest non-met 

organ/tissue All digestive
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 20 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

231 CA IN SITU RESPIRATORY 

231.0 CA IN SITU LARYNX ET2 Other respiratory

231.1 CA IN SITU TRACHEA BB Lung

231.2 CA IN SITU BRONCHUS/LUNG Lung Lung

231.8 CA IN SITU RESP SYS NEC Lung Other respiratory

231.9 CA IN SITU RESP SYS NOS Lung Other respiratory

232 CARCINOMA IN SITU SKIN 

232.0 CA IN SITU SKIN LIP Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.1 CA IN SITU EYELID Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.2 CA IN SITU SKIN EAR Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.3 CA IN SITU SKIN FACE NEC Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.4 CA IN SITU SCALP Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.5 CA IN SITU SKIN TRUNK Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.6 CA IN SITU SKIN ARM Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.7 CA IN SITU SKIN LEG Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.8 CA IN SITU SKIN NEC Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

232.9 CA IN SITU SKIN NOS Skin

Malignant melanoma AND

Non-melanoma skin-Squamous cell

233 CA IN SITU BREAST/GU 

233.0 CA IN SITU BREAST Breast Breast

233.1 CA IN SITU CERVIX UTERI Uterus Female genitalia less ovary

233.2 CA IN SITU UTERUS NEC Uterus Female genitalia less ovary

233.3 CA IN SITU FEM GEN NEC Uterus

Female genitalia less ovary AND

Ovary

233.4 CA IN SITU PROSTATE 

Highest non-met 

organ/tissue All male genitalia

233.5 CA IN SITU PENIS Testes All male genitalia

233.6 CA IN SITU MALE GEN NEC Testes All male genitalia

233.7 CA IN SITU BLADDER Bladder Bladder

233.9 CA IN SITU URINARY NEC Medical review Urinary organs less bladder

234 CA IN SITU NEC/NOS 

234.0 CA IN SITU EYE Brain Eye

234.8 CA IN SITU NEC 

Highest non-met 

organ/tissue Other and ill-defined sites

234.9 CA IN SITU NOS 

Highest non-met 

organ/tissue Other and ill-defined sites
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 21 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

235 UNCERT BEHAV NEOPLASM GI/RESP 

235.0 UNCERT BEHAV NEOPLASM SALIVARY 

Highest non-met 

organ/tissue Oral cav. and pharynx

235.1 UNCERT BEHAV NEOPLASM ORAL/PHAR 

Highest non-met 

organ/tissue Oral cav. and pharynx

235.2

 UNCERT BEHAV NEOPLASM INTESTINE 

(stomach) Stomach Stomach

235.2

 UNCERT BEHAV NEOPLASM INTESTINE 

(colon) Colon Colon

235.2

 UNCERT BEHAV NEOPLASM INTESTINE 

(rectum) LLI Rectum

235.3 UNCERT BEHAV NEOPLASM LIVER Liver Liver

235.4 UNCERT BEHAV NEOPLASM PERITONEUM 

Highest non-met 

organ/tissue All digestive

235.5 UNCERT BEHAV NEOPLASM GI NEC Colon All digestive

235.6 UNCERT BEHAV NEOPLASM LARYNX ET2 Other respiratory

235.7 UNCERT BEHAV NEOPLASM LUNG Lung Lung

235.8 UNCERT BEHAV NEOPLASM PLEURA Lung Other respiratory

235.9 UNCERT BEHAV NEOPLASM RESP NEC Lung Other respiratory

236 UNCERT BEHAV NEOPLASM GU 

236.0 UNCERT BEHAV NEOPLASM UTERUS Uterus Female genitalia, less ovary

236.1 UNCERT BEHAV NEOPLASM PLACENTA Uterus Female genitalia, less ovary

236.2 UNCERT BEHAV NEOPLASM OVARY Ovaries Ovary

236.3 UNCERT BEHAV NEOPLASM FEMALE NEC Medical review Female genitalia, less ovary

236.4 UNCERT BEHAV NEOPLASM TESTIS Testes All male genitalia

236.5 UNCERT BEHAV NEOPLASM PROSTATE 

Highest non-met 

organ/tissue All male genitalia

236.6 UNCERT BEHAV NEOPLASM MALE NEC Testes All male genitalia

236.7 UNCERT BEHAV NEOPLASM BLADDER Bladder Bladder

236.9 UNCERT BEHAV NEOPLASM OTHER URINAR Medical review Urinary organs less bladder

236.90 UNCERT BEHAV NEOPLASM URINAR NOS Medical review Urinary organs less bladder

236.91 UNCERT BEHAV NEOPLASM KIDNEY Medical review Urinary organs less bladder

236.99 UNCERT BEHAV NEOPLASM URINAR NEC Medical review Urinary organs less bladder

237 UNCER NEOPLASM ENDOCRINE/NERV 

237.0 UNCERT BEHAV NEOPLASM PITUITARY Brain Thyroid

237.1 UNCERT BEHAV NEOPLASM PINEAL Brain Thyroid

237.2 UNCERT BEHAV NEOPLASM ADRENAL Adrenal Urinary organs less bladder

237.3 UNCERT BEHAV NEOPLASM PARAGANG Brain Nervous system

237.4 UNCER NEOPLASM ENDOCRINE NEC Medical review Thyroid

237.5 UNCERT BEH NEOPLASM BRAIN/SPINAL Brain Nervous system

237.6 UNCERT BEHAV NEOPLASM MENINGES Brain Nervous system

237.7 NEUROFIBROMATOSIS Medical review Nervous system

237.70 NEUROFIBROMATOSIS NOS Medical review Nervous system

237.71 NEUROFIBROMATOSIS TYPE I Medical review Nervous system

237.72 NEUROFIBROMATOSIS TYP II Medical review Nervous system

237.9 UNCERT BEH NEOPLASM NERV SYS NEC Medical review Nervous system
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 22 of 24

Table 1 (cont)

ICD-9

Code Cancer code explanation

IMBA applicable

organ/tissue IREP model

238 UNCERT BEHAV NEOPLASM NEC/NOS 

238.0 UNCERT BEHAV NEOPLASM BONE Medical review Bone

238.1

 UNCERT BEHAV NEOPLASM SOFT 

TISSU Medical review Connective Tissue

238.2 UNCERT BEHAV NEOPLASM SKIN Medical review

Malignant melanoma AND

non-melanoma skin-Basal cell

238.3 UNCERT BEHAV NEOPLASM BREAST Medical review Breast

238.4 POLYCYTHEMIA

Red Bone 

Marrow Bone

238.5 MASTOCYTOMA NOS 

Red Bone 

Marrow Lymphoma and multiple myeloma

238.6 PLASMACYTOMA NOS 

Red Bone 

Marrow Lymphoma and multiple myeloma

238.7 LYMPHOPROLIFERAT DISEASE NOS 

Red Bone 

Marrow Lymphoma and multiple myeloma

238.8 UNCERT BEHAVIOR NEOPLASM NEC Medical review Other and ill-defined sites

238.9 UNCERT BEHAVIOR NEOPLASM NOS Medical review Other and ill-defined sites

239 UNSPECIFIED NEOPLASM 

239.0 DIGESTIVE NEOPLASM NOS Medical review All digestive

239.1 RESPIRATORY NEOPLASM NOS Medical review

Lung AND

Other respiratory

239.2 BONE/SKIN NEOPLASM NOS (Bone) Medical review Bone

239.2 BONE/SKIN NEOPLASM NOS (Skin) Medical review Non-melanoma skin-Basal cell

239.3 BREAST NEOPLASM NOS Breast Breast

239.4 BLADDER NEOPLASM NOS Bladder Bladder

239.5 OTHER GU NEOPLASM NOS (Female) Medical review

Female genitalia less ovary AND

Ovary AND

All urinary organs

239.5 OTHER GU NEOPLASM NOS (Male) Medical review

All male genitalia AND

All urinary organs

239.6 BRAIN NEOPLASM NOS Brain Nervous system

239.7 BRAIN/NERV NEOPLASM NOS Medical review Nervous system

239.7 ENDOCRINE NOS Medical review

Thyroid AND

Other endocrine glands

239.8 NEOPLASM NOS, SITE NEC Medical review Other and ill-defined sites

239.9 NEOPLASM NOS Medical review Other and ill-defined sites

289 OTHER SPECIFIED BLOOD DISORDER

289.8

 OTHER SPECIFIED DISEASES OF BLOOD

 AND BLOOD-FORMING ORGANS

Red Bone 

Marrow Bone

4.0 Discussion

4.1 Highest Non-metabolic organ

The dose estimate for a number of tissues is based on the highest non-metabolic organ dose, 

designated as “Highest non-met organ/tissue” in the table. Metabolic organs are those that are 

specifically modeled by the ICRP for a particular element. The biokinetic models are based on the 

behavior of the particular element in the body, so the metabolic organs vary with the element of 

interest. The metabolic organs also include the gastrointestinal tract (ICRP 30) and, in the case of 
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 23 of 24

inhalation, the respiratory tract (ICRP 66).

For radionuclides that primarily emit alpha or beta radiation, the soft tissue compartment becomes the 

primary recipient of dose. This compartment contains all the organs not specifically accounted for in 

the metabolic model. This compartment accounts for the dose delivered by material actually deposited 

in that tissue. An additional source of exposure to the tissue is known as photon cross-irradiation. 

This cross-irradiation is the exposure to a tissue from photons originating in other tissues.

When the energy emitted by a radionuclide is primarily alpha or beta radiation, the soft tissue 

compartment becomes the primary source of dose. Under this scenario most of the non-metabolic 

organs receive the same dose. For radionuclides where photon emissions are a major source of 

energy emitted, the non-metabolic organ doses can vary due to their relative proximity to the metabolic 

organs in which the radionuclides concentrate. IMBA calculates the dose from both means of 

irradiation and sums them. For many radionuclides (predominately alpha and beta emitters) this will 

cause only minor differences in doses to non-metabolic organs, so choosing the highest is a realistic 

assumption with only minor (if any) overestimation.

It is conceivable that a situation could arise where a photon emitting radionuclide causes a large 

difference in doses delivered to non-metabolic organs. In accordance with the Internal Dose 

Reconstruction Implementation Guideline, it is acceptable in these situations to base the dose on an 

organ that is not the highest non-metabolic organ. The choice in these cases should be based on the 

proximity of the model organ to the actual organ of interest.

4.2 Medical review

Due to the complexity of determining the appropriate organ/tissue for some ICD-9 code cancers, a 

medical review by an ORAU team physician is required to determine the organ/tissue to use in IMBA

for those cancers. These cancers have been designated in the table as “Medical review.” The ORAU 

team physician will recommend to the dose reconstructor the appropriate organ/tissue for dose 

estimation purposes.

4.3 Bladder

When the term “Bladder” is used in the table with no modifier, this represents the urinary bladder. 

When the organ of interest is the gallbladder, “Gallbladder” is specified clearly in the table above.

5.0 References

1. 42 CFR § 81, Guidelines for Determining the Probability of Causation Under the Energy 

Employees Occupational Illness Compensation Program Act of 2000; Final Rule, Federal 

Register/Vol.67, No. 85/Thursday, May 2, 2002, p 22296

2. NIOSH, (2002) Internal Dose Reconstruction Implementation Guideline, Rev 0, OCAS-IG-002, 

National Institute for Occupational Safety and Health, Office of Compensation Analysis and 

Support, Cincinnati, Ohio, August 2002

3. ACJ & Associates and the UK National Radiological Protection Board, Integrated Modules for 

Bioassay Analysis, (IMBA), Software produced for NIOSH-OCAS as part of the EEOICPA 

Program, UK, July 2003
Effective Date: 11/03/2003 Revision No. 00 Document No. ORAUT-OTIB-0005 Page 24 of 24

4. NIOSH, NIOSH-Interactive RadioEpidemiological Program (NIOSH-IREP), Technical 

Documentation, Office of Compensation Analysis and Support, Cincinnati, Ohio, June 2002