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Dimethyl sulfate																				Related Pages
Synonyms & Trade Names
			Dimethyl ester of sulfuric acid, Dimethylsulfate, Methyl sulfate
CAS No.
			77-78-1
	RTECS No.
			WS8225000
	DOT ID & Guide
			1595 156

Formula(CH3)2SO4
	Conversion
			1 ppm = 5.16 mg/m3
	IDLH
			Ca [7 ppm]See: 77781

Exposure Limits
			NIOSH RELCa TWA 0.1 ppm (0.5 mg/m3) [skin] See Appendix A
					OSHA PEL TWA 1 ppm (5 mg/m3) [skin] See Appendix G
	Measurement Methods
			**NIOSH** 2524
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless, oily liquid with a faint, onion-like odor.													
										
Molecular Weight126.1	
	Boiling Point370°F (Decomposes)
	Freezing Point-25°F
	Solubility(64°F): 3%
	Vapor Pressure0.1 mmHg
	Ionization Potential?											
Specific Gravity1.33	
	Flash Point182°F
	Upper Explosive Limit?
	Lower Explosive Limit?
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Incompatibilities & Reactivities
			Strong oxidizers, ammonia solutions
					[Note: Decomposes in water to sulfuric acid; corrosive to metals.]
Exposure Routes
			inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, nose; headache; dizziness; conjunctivitis; photophobia (abnormal visual intolerance to light); periorbital (situated around the eye) edema; dysphonia, aphonia, dysphagia, productive cough; chest pain; dyspnea (breathing difficulty), cyanosis; vomiting, diarrhea; dysuria; analgesia; fever; proteinuria, hematuria (blood in the urine); eye, skin burns; delirium; [potential occupational carcinogen]
Target Organs
			Eyes, skin, respiratory system, liver, kidneys, central nervous system
Cancer Site[in animals: nasal & lung cancer]										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet or contaminated
							**Change:**No recommendation
							**Provide:**Eyewash, Quick drench
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Water flush immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH****At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted canister providing protection against the compound of concernAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0148
					  MEDICAL TESTS: 0084

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Chemical Names, Synonyms and Trade Names
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CAS Numbers
RTECS Numbers
Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
First Aid Procedures Follow NIOSH Facebook
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