Prepared by R.R. Donnelley Financial -- EX-10.16(c)




 Exhibit 10.16(c) 

 

CONFIDENTIAL 

[***] Certain information in this document has been omitted and filed separately with the Securities and Exchange Commission. Confidential
treatment has been requested with respect to the omitted portions. 

 AMENDMENT #2 TO TASK ORDER #13 

COHERUS Project Number: CHS0214-02 

MEDPACE Project Number: ETA302 

This Amendment #2 (“Amendment #2”) to Task Order #13 effective as of 18 October 2013 (“Task
Order”), is by and between Coherus Bioscience, Inc., a Delaware corporation with its principal place of business at 201 Redwood Shores Parkway, Suite 200, Redwood City, CA 94065 (“Sponsor”), and Medpace, Inc.,
with its principal place of business at 5375 Medpace Way, Cincinnati, Ohio 45227 (“Medpace”). This Amendment #2 shall be effective 21 May 2014. 

WITNESSETH: 

WHEREAS, the Parties have entered into Task Order pursuant and subject to the terms of the Master Service Agreement dated
23 January 2012, (the “Agreement”); and 
 WHEREAS, the Parties desire to amend Task Order in connection with a
Phase 3, A Double-Blind, Randomized, Parallel-Group, Active-Control Study to Compare the Efficacy and Safety of CHS-0214 DP Versus Enbrel® in Subjects with Rheumatoid Arthritis and
Inadequate Response to Treatment with Methotrexate to include a portion of the Investigator payments for sites in Japan. 
 NOW,
THEREFORE, in consideration of the mutual covenants contained herein, the Parties hereby agree as follows to the revised Scope of Work: 
  

	 	1.	The [***] Fees line item included under the Pre-Funded Expenses category in Appendix C: Services and Budget is hereby increased from [***] to [***]. (“Increase”). 


 

	 	2.	As a result of the increase in the Budget, Appendix D: Payment Schedule, attached to the Task Order is hereby amended to include the following: 


A total of [***] is due upon execution of Amendment #2. The remainder of the Increase will be paid in accordance with the terms of
Appendix D: Payment Schedule, attached to the Task Order. 
 The total amount payable by Sponsor to Medpace under this Amendment #2 for Medpace
Direct Fees, Pass-through Expenses, and Pre-funded Expenses shall not exceed the amount of [***] without prior written consent of both parties. The total value of Task Order and all subsequent amendments is now [***]. 

  

			
	



	  	 Amendment #2 to Task Order #13

Coherus Biosciences, Inc.
 CHS-0214-02
/ ETA302
 Page 1












																	
	 	  	Direct Fees	 	 	Pass Through Costs	 	 	Pre-funded Expenses	 	 	TOTAL	 
	 Task Order #13
	  	 	[***	] 	 	 	[***	] 	 	 	[***	] 	 	 	[***	] 
	 Amendment #1
	  	 	[***	] 	 	 	[***	] 	 	 	[***	] 	 	 	[***	] 
	 Amendment #2
	  	 	[***	] 	 	 	[***	] 	 	 	[***	] 	 	 	[***	] 
	 TOTAL
	  	 	[***	] 	 	 	[***	] 	 	 	[***	] 	 	 	[***	] 

 All other provisions of the Agreement and Task Order shall remain unchanged and in effect. 

IN WITNESS WHEREOF, the Parties have hereunto signed this Amendment #2 to Task Order in their official capacities which shall be effective on the
day and year listed above. 
  

			
	MEDPACE, INC.
		
	Signature:	 	/s/ John Wynne
		
	By:	 	John Wynne
		 	     (Print Name)
  

Vice President

	Title:	 	Commercial Operations

  

			
	COHERUS BIOSCIENCES, INC.
		
	Signature:	 	/s/ Dennis M. Lanfear
		
	By:	 	Dennis M. Lanfear
		 	    (Print Name)
		
	Title:	 	President & CEO


  

			
	



	  	 Amendment #2 to Task Order #13

Coherus Biosciences, Inc.
 CHS-0214-02
/ ETA302
 Page 2



			
		
	 [***]  Certain information in this document has been omitted and filed separately with the Securities and Exchange
Commission. Confidential treatment has been requested with respect to the omitted portions.