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Methyl isocyanate																				Related Pages
Synonyms & Trade Names
			Methyl ester of isocyanic acid, MIC
CAS No.
			624-83-9
	RTECS No.
			NQ9450000
	DOT ID & Guide
			2480 155

FormulaCH3NCO
	Conversion
			1 ppm = 2.34 mg/m3
	IDLH
			0.12 ppmSee: 2017-105

Exposure Limits
			NIOSH RELTWA 0.02 ppm (0.05 mg/m3) [skin]
					OSHA PEL TWA 0.02 ppm (0.05 mg/m3) [skin]
	Measurement Methods
			**OSHA** 54
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless liquid with a sharp, pungent odor.													
										
Molecular Weight57.1	
	Boiling Point102-104°F
	Freezing Point-49°F
	Solubility(59°F): 10%
	Vapor Pressure348 mmHg
	Ionization Potential10.67 eV											
Specific Gravity0.96	
	Flash Point19°F
	Upper Explosive Limit26%
	Lower Explosive Limit5.3%
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Incompatibilities & Reactivities
			Water, oxidizers, acids, alkalis, amines, iron, tin, copper
					[Note: Usually contains inhibitors to prevent polymerization.]
Exposure Routes
			inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, skin, nose, throat; resp sensitization, cough, pulmonary secretions, chest pain, dyspnea (breathing difficulty); asthma; eye, skin damage; In Animals: pulmonary edema
Target Organs
			Eyes, skin, respiratory system
										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet (flammable)
							**Change:**No recommendation
							**Provide:**Eyewash, Quick drench
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Water flush immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH/OSHA****Up to 0.2 ppm**: (APF = 10) Any supplied-air respirator***Up to 0.5 ppm**: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode***Up to 1 ppm**: (APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece**Up to 3 ppm**: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
**Emergency or planned entry into unknown concentrations or IDLH conditions:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0004
					  MEDICAL TESTS: 0143

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
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Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
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