Skip directly to site content Skip directly to search


Español  Other Languages


Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
 Search
		×
			NIOSH
			NIOSH
				All CDC
				Submit
			For a full list of topics:A-Z Index
			Advanced Search
		Advanced Search


NIOSH Radiation Dose Reconstruction Program


Section Navigation
			
			CDC Home








alert icon
            Cybersecurity Modernization Initiative
                We are taking steps to continue to modernize and secure our data, applications, and systems. We completed the first phase and restored many of the functions put on pause in May 2021. Now that the first phase is complete, work will resume at a slower pace but will speed up as new systems and applications are brought online. For more information and updates, please visit our Cybersecurity Modernization Initiative web page.
								

				Mallinckrodt Chemical Co., Destrehan St. Plant						Print
																Related Pages
										On This Page
			Special Exposure CohortTechnical DocumentsAdvisory Board and NIOSH DiscussionsProgram Evaluation Plans and Reports (PEPs and PERs)Public CommentsDocument Archive
		
(Site Profile/Docket Number 014)
Location: St. Louis, Missouri
Also known as: Mallinckrodt Chemical Works, MCW, St. Louis Downtown Site
Special Exposure Cohort Petition Information
The Special Exposure Cohort (SEC) is a unique category of employees established by the Act (42 CFR Part 83). Claims compensated under the SEC do not have to go through the dose reconstruction process. To qualify for compensation under the SEC, a covered employee must meet specific requirements (e.g., must have at least one of 22 “specified cancers,” and have worked for a specified time period at one of the SEC sites). Classes of employees and work sites can be considered for addition to the SEC through a NIOSH petition process. More information about the Special Exposure Cohort can be found on our Frequently Asked Questions page.
Open/Active SEC Petitions
To date, there are no open/active SEC petitions from Mallinckrodt Chemical Co., Destrehan St. Plant.
Class(es) Added to the SEC
Employees of the DOE or DOE contractors or subcontractors employed by the Uranium Division of Mallinckrodt Chemical Works, Destrehan Street Facility, during the period from 1942 through 1948 and who were employed for a number of work days aggregating at least 250 work days either solely under this employment or in combination with work days within the parameters (excluding aggregate work day requirements) established for other classes of employees included in the SEC
**Note:** This class was established by Petition 12
Department of Energy (DOE) employees or DOE contractor or subcontractor employees who worked in the Uranium Division at the Destrehan Street Facility of Mallinckrodt Chemical Works from 1949 to 1957 and who were employed for a number of work days aggregating at least 250 work days either solely under this employment or in combination with work days within the parameters (excluding aggregate work day requirements) established for other classes of employees included in the SEC
**Note:** This class was established by Petition 12
All employees of DOE, its predecessor agencies, and their contractors and subcontractors who worked in the Uranium Division at the Mallinckrodt Chemical Co., Destrehan Street Plant in St. Louis, Missouri, from January 1, 1958 to December 31, 1958, for a number of work days aggregating at least 250 work days, occurring either solely under this employment or in combination with work days within the parameters established for one or more other classes of employees included in the SEC
**Note:** This class was established by Petition 133Petitions Qualified for Evaluation
Below is a list of the petitions that qualified for evaluation. Select a petition on the list to view the table for that particular petition.
Petition 12 (Jan 1, 1942 to Dec 31, 1957)
	Petition 12
Steps in Petition Process:
Petition Details:Date Received
July 21, 2004Date Qualified for Evaluation
November 24, 2004Summary of Information in Petition
**Location:** St. Louis, Missouri
**Job Titles and/or Job Duties:** All employees that conducted Atomic Energy Commission (AEC) work at the Destrehan Street Plant
**Period of Employment:** January 1, 1942 through December 31, 1957
**Note:** The information above is what qualified for evaluation. During our evaluation of whether dose reconstructions can adequately be completed for the above job titles and period of employment, information may cause NIOSH to change some the dates or job titles/duties. Therefore, as this petition proceeds through the SEC petition process and if an SEC class is proposed, the proposed class may not exactly match the above information.Copy of the Petition Received
July 21, 2004
(January 1, 1942 through December 31, 1957)
Pages 1-23 [1.13 MB (23 pages)]
Pages 24-47 [1.67 MB (24 pages)]
Page 48-70 [1.04 MB (23 pages)]Federal Register Notice Announcing that a Mallinckrodt Chemical Co., Destrehan St. Plant SEC Petition has met the Minimum Qualifications for Review and Evaluation
December 20, 2004 [45 KB (1 page)](January 1, 1942 through December 31, 1957)SEC Petition Evaluation Report
February 1, 2005 [145 KB (26 pages)](January 1, 1942 through December 31, 1945)
Revised February 2, 2005, Rev. 2 [312 KB (48 pages)](January 1, 1946 through December 31, 1957)
Addendum March 30, 2005 [624 KB (17 pages)](January 1, 1949 through December 31, 1957)Evaluation Report Sent to the Advisory Board
February 2, 2005 (Revision 2)
(January 1, 1946 through December 31, 1957)Petition Discussed by the Advisory Board
The Advisory Board discussed the Mallinckrodt Chemical Plant petitions on February 8, 2005; April 27, 2005; July 6, 2006; and August 26,2005.
**Note:** Agendas and transcripts for Board meetings will be posted on the Advisory Board and Public Meetings page as soon as they become available.Advisory Board Recommendation on SEC Petition
March 11, 2005 [119 KB (2 pages)](January 1, 1942 through December 31, 1948)
September 15, 2005 [482 KB (3 pages)](January 1, 1949 through December 31, 1957)HHS Letters to Congress Regarding the SEC Petition
April 11, 2005 [438 KB (9 pages)](January 1, 1942 through December 31, 1948)
October 14, 2005 [287 KB (8 pages)](January 1, 1949 through December 31, 1957)HHS Designation/Determination of Additional Members to the SEC
**Designation:**
April 11, 2005 [445 KB (5 pages)](January 1, 1942 through December 31, 1948)
October 14, 2005 [294 KB (5 pages)](January 1, 1949 through December 31, 1957)
Administrative Review Documentation March 29, 2006 [462 KB (8 pages)](January 1, 1942 through December 31, 1948)
**Note:** A “designation” means that HHS is recommending a class be added to the SEC. A “determination” means that HHS is recommending a class **not** be added to the SEC.Federal Register Notice: Designation/Determination Of a Class of Employees for Addition to the Special Exposure Cohort
**Designation:**
April 11, 2005 [42 KB (1 page)](January 1, 1942 through December 31, 1948)
November 4, 2005 [42 KB (1 page)](January 1, 1949 through December 31, 1957)
**Note:** A “designation” will be published if there is a recommendation to add a class to the SEC. A “determination” will be published if there is a recommendation **not** to add a class to the SEC.Effective Date for the SEC Class
May 12, 2005(January 1, 1942 through December 31, 1948)
November 13, 2005(January 1, 1949 through December 31, 1957)
**Note:** This only applies if the class is added to the SEC.Federal Register Notice: Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort
May 23, 2005 [42 KB (1 pages)](January 1, 1942 through December 31, 1948)
December 27, 2005 [42 KB (1 page)](January 1, 1949 through December 31, 1957)
**Note:** This only applies if the class is added to the SEC.Letter to DOL Regarding the Addition of a New Class of Employees to the SEC
May 17, 2005 [35 KB (1 page)](January 1, 1942 through December 31, 1948)
November 23, 2005 [430 KB (1 page)](January 1, 1949 through December 31, 1957)
February 22, 2006 (Additional Letter to DOL) [19 KB (1 page)](January 1, 1949 through December 31, 1957)
**Note:** This only applies if the class is added to the SEC.Letter from DOL Regarding the Return of All Cases for the New SEC Class
June 17, 2005 (1942-1948) [204 KB (2 pages)](January 1, 1942 through December 31, 1948)
December 7, 2005 [215 KB (3 pages)](January 1, 1949 through December 31, 1957)
**Note:** This only applies if the class is added to the SEC.Petition 133 (Jan 1, 1958 to Dec 31, 1958)
	Petition 133
Steps in Petition Process:
Petition Details:Date Received
November 18, 2008Date Qualified for Evaluation
November 19, 2008Summary of Information in Petition
**Job Titles and/or Job Duties:** All employees who worked with uranium
**Period of Employment:** January 1, 1958 to December 31, 1958
**Note:** The information above is what qualified for evaluation. During our evaluation of whether dose reconstructions can adequately be completed for the above job titles and period of employment, information may cause NIOSH to change some the dates or job titles/duties. Therefore, as this petition proceeds through the SEC petition process and if an SEC class is proposed, the proposed class may not exactly match the above information.Copy of the Petition Received
November 18, 2008 [82 KB (2 pages)](January 1, 1958 through December 31, 1958Federal Register Notice Announcing that a Mallinckrodt Chemical Co., Destrehan St. Plant SEC Petition has met the Minimum Qualifications for Review and Evaluation
December 10, 2008 [19 KB (1 page)](January 1, 1958 to December 31, 1958)SEC Petition Evaluation Report
December 1, 2008 [107 KB (19 pages)](January 1, 1958 to December 31, 1958)Evaluation Report Sent to the Advisory Board
December 2, 2008(January 1, 1958 to December 31, 1958)Petition Discussed by the Advisory Board
The Advisory Board discussed the Mallinckrodt Chemical Plant petitions on February 8, 2005; April 27, 2005; July 6, 2006; and August 26,2005.
**Note:** Agendas and transcripts for Board meetings will be posted on the Advisory Board and Public Meetings page as soon as they become available.Advisory Board Recommendation on SEC Petition
December 18, 2008 [526 KB (2 pages)](January 1, 1958 to December 31, 1958)HHS Letters to Congress Regarding the SEC Petition
January 16, 2009 [412 KB (9 pages)](January 1, 1958 to December 31, 1958)HHS Designation/Determination of Additional Members to the SEC
**Designation:**
January 16, 2009 [417 KB (4 pages)](January 1, 1958 to December 31, 1958)
**Note:** A “designation” means that HHS is recommending a class be added to the SEC. A “determination” means that HHS is recommending a class **not** be added to the SEC.Federal Register Notice: Designation/Determination Of a Class of Employees for Addition to the Special Exposure Cohort
**Designation:**
January 29, 2009 [40 KB (1 page)](January 1, 1958 to December 31, 1958)
**Note:** A “designation” will be published if there is a recommendation to add a class to the SEC. A “determination” will be published if there is a recommendation **not** to add a class to the SEC.Effective Date for the SEC Class
February 15, 2009(January 1, 1958 to December 31, 1958)
**Note:** This only applies if the class is added to the SEC.Federal Register Notice: Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort
February 27, 2009 [40 KB (1 page)](January 1, 1958 to December 31, 1958)
**Note:** This only applies if the class is added to the SEC.Letter to DOL Regarding the Addition of a New Class of Employees to the SEC
February 24, 2009 [17 KB (1 page)](January 1, 1958 to December 31, 1958)
**Note:** This only applies if the class is added to the SEC.
Technical Documents
If the energy employee’s personal radiation information is incomplete, NIOSH will use other sources to estimate the radiation dose. This may involve using technical documents called Site Profiles, Technical Basis Documents, and Technical Information Bulletins.
Site Profile
Basis for Development of an Exposure Matrix for the Mallinckrodt Chemical Company St. Louis Downtown Site and the St. Louis Airport Site, St. Louis, Missouri [3 MB (242 pages)]
            Revised November 22, 2010
**Revision Includes:** Incorporates SEC-00150 information in Section 1.0 for the St. Louis Airport Storage Site (SLAPS) as instructed by NIOSH. Additional changes in document include deletion of Sections 8.4, 8.6, and 8.8 and replacement of the material that is still applicable (considering the SEC determination) along with expanded instruction specific to SLAPS into a new Section, 9.0. In addition, the designation of covered periods noted in Section 1.0 was updated to reflect current program guidance. Incorporates formal internal and NIOSH review comments. Section 7.4 changed to clarify that medical x-ray exposure is not to be assigned at the Mallinckrodt Destrehan Street Plant due to the fact that the examinations were performed offsite. Section 1, 7.0 and 7.1 changed to clarify that external exposure to monitored employees is to be included in dose reconstructions for individuals employed prior to 1949. This exposure was previously excluded from dose reconstruction reports.
Technical Information Bulletins (TIBs)
DCAS-TIB-0013 Rev-01: Selected Geometric Exposure Scenario Considerations for External Dose Reconstruction at Uranium Facilities [554 KB (16 pages)]
            November 23, 2010
**Note:** Document was previously titled “Special External Dose Reconstruction Considerations for Mallinckrodt Workers.”
**Revision Includes:** Incorporates SC&A comments; reorganized procedure format; included dose reconstruction instructions for the application of geometric correction factors to the upper and lower torso; added information to clarify the bounding parameters associated with the Attila computation; NIOSH internal comments including procedure title change and applicability to other uranium facilities.Advisory Board and NIOSH Comments and Discussion Papers on Mallinckrodt Chemical Co., Destrehan St. Plant
The Mallinckrodt Chemical Co., Destrehan St. Plant discussion papers listed below are working documents prepared by NIOSH or its contractor for use in discussions with the Advisory Board on Radiation and Worker Health or its Working Groups or Subcommittees. Draft, preliminary, interim, and white paper documents are not final NIOSH or Advisory Board (or their technical support and review contractors) positions unless specifically marked as such. These documents represent preliminary positions taken on technical issues prepared by NIOSH or its contractor.
The discussion papers have been reviewed to identify and redact any information that is protected by the Privacy Act 5 USC §552a and have been cleared for distribution.
SC&A Presentation: A Review of NIOSH’s Program Evaluation Report DCAS-PER-040, “Mallinckrodt TBD Revisions” [445 KB (22 pages)]
            Presentation at the November 16, 2023, Teleconference Meeting of the Subcommittee for Procedure Reviews
SC&A Draft: A Review of NIOSH’s Program Evaluation Report DCAS-PER-040, “Mallinckrodt TBD Revisions” [663 KB (21 pages)]
            Contract No. 75D30119C04183
            Document No. SCA-TR-2023-PR040, Revision 1
            September 21, 2023
Review of NIOSH Site Profile for Mallinckrodt Chemical Company, St. Louis Downtown Site, St. Louis, Mo. [355 KB (102 pages) ]
            Contract No. 200-2004-03805
            Task Order No. 1
            SCA-TR-TASK1-0002
            January 31, 2005Program Evaluation Plans (PEPs) and Program Evaluation Reports (PERs)
NIOSH is committed to applying the best available science in dose reconstructions. In keeping with this commitment, completed cases with probabilities of causation less than 50% are reviewed as relevant new information becomes available. The results of these reviews are described in a Program Evaluation Report (PER). The PER details the effect, if any, of the new information on the completed dose reconstruction. If it appears that the new information may result in an increase in dose for a completed dose reconstruction with a probability of causation of less than 50%, NIOSH is committed to working with the Department of Labor to reopen and rework the dose reconstruction, as appropriate. A Program Evaluation Plan (PEP) describes plans for evaluating specific program details or issues.
DCAS-PER-040 Rev-0: Mallinckrodt TBD (ORAUT-TKBS-0005) Revision [88 KB (3 pages)]September 10, 2013
**About this Document:** Considers the effect of Revision 3 on claims that were completed using revision 2 or Revision 2 PC-1.
**Summary:** For the ninety-one claims requiring further evaluation, dose was recalculated using all current dose reconstruction methods, including those in the current version of the TBD. From that recalculated dose, a new probability of causation was determined. The probability of causation remained below 45% for 86 of the 91 claims. For three of the remaining five claims, the probability of causation fell between 45% and 50%. In accordance with NIOSH procedures, IREP was run 30 times with 10,000 iterations for each run. The final probability of causation remained below 50% for all three claims. The final two resulted in a probability of causation greater than 50%. In both cases, this resulted primarily from the inclusion of monitored external dose between 1942 and 1948 that had not previously been included. NIOSH will notify DOL of all these results and request a return of the two claims that would now be greater than 50%.
OCAS-PER-0015 Rev-00: Program Evaluation Report: Mallinckrodt TBD Revision [16 KB (2 pages)]July 31, 2007
**About this Document:** New document to determine which previously completed claims require evaluation for the effect of revising the Mallinckrodt TBD.
**Summary:** It is not possible to determine the magnitude of the change to dose without a new dose estimate. Since (as of issuance of this PER) no Mallinckrodt claims have yet been completed with the newest revision to the TBD, NIOSH is requesting that all Mallinckrodt claims with a dose reconstruction performed using Revision 1 of ORAUT-TKBS-0005 that have a Probability of Causation less than 50% be returned for a new estimate. A list of the population of 16 potentially affected claims is attached. A new dose reconstruction will be completed for each of the claims using the latest revision to the Mallinckrodt TBD.Public Comments on Mallinckrodt Chemical Co., Destrehan St. Plant Documents
How to Submit Comments
Comments on Mallinckrodt Chemical Co., Destrehan St. Plant Documents can be submitted to the NIOSH Docket Officer electronically by email at nioshdocket@cdc.gov or printed comments can be mailed to:
NIOSH Docket Office
Robert A. Taft Laboratories, MS-C34
1090 Tusculum Avenue
Cincinnati, OH 45226
Please include the Site Profile/Docket Number (014) on all comments.
Comments Received
Comments from Daniel W. McKeel, Associate Professor of Pathology and Immunology, Washington University School of Medicine, St. Louis [478 KB (14 pages)]
            April 19, 2005Document Archive for Mallinckrodt Chemical Co., Destrehan St. Plant
Site Profile: Basis for Development of an Exposure Matrix for the Mallinckrodt Chemical Company St. Louis Downtown Site and the St. Louis Airport Site, St. Louis, Missouri
Page Change Revision May 25, 2009 [3 MB (225 pages)]
**Page Change Revision Includes:** Page change initiated to incorporate SEC information on pages 10-13 in Section 1.0 (extension of class to 12/31/1958) as instructed by NIOSH. Updated NIOSH required language on pages 10 and 11 in Section 1.0. Added information on pages 106-108 in Section 6.5. Updated NIOSH reference on pages 106-108, 124, 128 and 216 in Sections 7.1, 7.3, 8.5, 8.6, and Attachment A, respectively. Added reference on page 141 in Reference Section. On pages 158-160, updated NIOSH and ORAUT references in Reference Section. On page 210, updated NIOSH reference in Table A-34. Table A-40 on page 215 was revised to clarify that tabulated intakes represent gross alpha activity and to provide guidance on isotopic mixture to be applied. Incorporates formal internal and NIOSH review comments.
Revised June 14, 2007 [3 MB (222 pages)]
**Revision Includes:** Reflects comments of the ABRWH. Constitutes a total rewrite of the document. Modified Purpose and Scope, and Appendix A to incorporate SEC information as instructed by NIOSH. Made minor editorial changes to eliminate readily discernible errors and eliminated extraneous intake tables. Added information to reconstruct doses from available monitoring and coworker data for the period 1949-1962, and to clarify some discrepancies between the early-in-the program draft and current guidance. Deleted Appendix D (which was formerly C). This revision changes the method for assigning uranium, radium and thorium coworker intakes and radon exposures and eliminates the application of equilibrium amounts of uranium progeny intakes to reconstruct dose. Incorporates formal internal and NIOSH review comments. Revised dates for operational period in sections 6 and 7 to end in 1958. Removed references to unmonitored thorium and radium exposures (since reconstruction of such exposures has been determined to be not feasible by the SEC action). Added a section titled “unmonitored raffinate exposures” to cover the period 1948 – 1958 and inserted the text “reserved” to indicate that reconstruction of internal exposure from such pathways is not covered in this TBD for the time period 1948 – 1958. This revision results in an increase in assigned dose and a PER is required.
Revised March 10, 2005 [2.7 MB (248 pages)]
**Revision Includes:** Incorporated comments on Section 8.0 and to incorporate additional lately captured information. Revision to incorporate comments on Sections 7.0 and 8.0; to incorporate additional lately captured information regarding site work and external and radon exposure rates; to incorporate neutron exposure information; to incorporate information about the St. Louis Airport Site (SLAPS); and to provide additional guidance to dose reconstructors. Section 7.0, regarding external dose, remains on hold. Incorporated NIOSH comments.
Approved October 24, 2003 [1.3 MB (124 pages)]
OCAS-TIB-0013 Rev-00: Special External Dose Reconstruction Considerations for Mallinckrodt Workers [351 KB (10 pages)]
            October 26, 2005
**About this Document:** Provides guidance on the application of geometry-based dose correction factors to external dosimetry badge data for Mallinckrodt workers in particular job classifications.
**Note:** Document title has changed to “Selected Geometric Exposure Scenario Considerations for External Dose Reconstruction at Uranium Facilities.”
							
					
							Last Reviewed:  June 30, 2022						Source: 	National Institute for Occupational Safety and Health
					Facebook
        Twitter
        LinkedIn
        Syndicate homeRadiation Dose ReconstructionAbout DCASThe Act/EEOICPADose Reconstruction (DR)plus iconDataplus iconSourcesFormats & TypesSensitive DataWork History                            Phone CallData Search and Capture EffortsMethodsProductionTechnical Documents Used in Dose ReconstructionsProgram Evaluation Reports and PlansQuality Assurance and Quality ControlSupport ContractorSoftware (IMBA)RECA ClaimsProbability of Causationplus iconCalculating PCNews & UpdatesNIOSH-IREP SoftwareSpecial Exposure Cohortplus iconSubmit a PetitionCheck Petition Statusplus iconSEC Status TableGet HelpResidual ContaminationAdvisory Boardplus iconPublic MeetingsSubcommittee and Work GroupsSEC Petition RecommendationsTechnical Support for the Review of NIOSH Dose Reconstruction ProgramReports from the Advisory Board's Technical Support ContractorTechnical Review Summaries from the Technical Support ContractorProceduresCorrespondenceWork Site InformationPublications & ProductsProgram ReviewsReports to CongressPolicies, Procedures, and GuidelinesNIOSH Public DocketRelated Program LinksContact UsHELPplus iconHelp A – ZAccessibilityAcronymsFrequently Asked Questions (FAQs)plus iconThe ActCase ConcernsClaimant CorrespondenceConflict or BiasDose ReconstructionFreedom of Information Act (FOIA)National Defense Authorization ActNIOSH-IREPProbability of CausationResidual Contamination ReportResponsibilities under Subtitle B of EEOICPA (The Act)Special Exposure CohortTechnical DocumentsWork History Phone CallGlossary Follow NIOSH Facebook
Pinterest
Twitter
YouTube
 NIOSH Homepage NIOSH A-Z
Workplace Safety & Health Topics
Publications and Products
Programs
Contact NIOSH


About CDC
					Contact Us
					800-232-4636
 Facebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat
 CONTACT CDC
				Contact Us
							Call 800-232-4636
							Email Us
			ABOUT CDC
				About CDC
							Jobs
							Funding
			POLICIES
				Accessibility
							External Links
							Privacy
							Policies
							No Fear Act
							FOIA
							OIG
							Nondiscrimination
							Vulnerability Disclosure Policy
			CONNECT WITH US
				Facebook
								Twitter
								Instagram
								LinkedIn
							Youtube
								Pinterest
								Snapchat
								Email
			LANGUAGES
				Español
							繁體中文
							Tiếng Việt
							한국어
							Tagalog
							Русский
							العربية
							Kreyòl Ayisyen
							Français
							Polski
							Português
							Italiano
							Deutsch
							日本語
							فارسی
							English


U.S. Department of Health & Human Services
			Accessibility
			External Links
			Privacy
			Policies
			No Fear Act
			FOIA
			Nondiscrimination
			OIG
			Vulnerability Disclosure Policy
			USA.gov


Exit Notification / Disclaimer Policy Close
 Links with this icon  indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
				Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
				You will be subject to the destination website's privacy policy when you follow the link.
				CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Website Disclaimers
 Cancel Continue