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Toluene-2,4-diisocyanate																				Related Pages
Synonyms & Trade Names
			TDI, 2,4-TDI, 2,4-Toluene diisocyanate
CAS No.
			584-84-9
	RTECS No.
			CZ6300000
	DOT ID & Guide
			2078 156

FormulaCH3C6H3(NCO)2
	Conversion
			1 ppm = 7.13 mg/m3
	IDLH
			Ca [2.5 ppm]See: 584849

Exposure Limits
			NIOSH RELCa See Appendix A
					OSHA PEL C 0.02 ppm (0.14 mg/m3) See Appendix G
	Measurement Methods
			**NIOSH** 2535 , 5521 , 5522 , 5525;**OSHA** 18 , 33 , 42
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless to pale-yellow solid or liquid (above 71°F) with a sharp, pungent odor.													
										
Molecular Weight174.2	
	Boiling Point484°F
	Melting Point71°F
	SolubilityInsoluble
	Vapor Pressure(77°F): 0.01 mmHg
	Ionization Potential?											
Specific Gravity1.22	
	Flash Point260°F
	Upper Explosive Limit9.5%
	Lower Explosive Limit0.9%
Class IIIB Combustible Liquid: Fl.P. at or above 200°F.
Incompatibilities & Reactivities
			Strong oxidizers, water, acids, bases & amines (may cause foam & spatter); alcohols
					[Note: Reacts slowly with water to form carbon dioxide and polyureas.]
Exposure Routes
			inhalation, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, skin, nose, throat; choke, paroxysmal cough; chest pain, retrosternal (occurring behind the sternum) soreness; nausea, vomiting, abdominal pain; bronchitis, bronchospasm, pulmonary edema; dyspnea (breathing difficulty), asthma; conjunctivitis, lacrimation (discharge of tears); dermatitis, skin sensitization; [potential occupational carcinogen]
Target Organs
			Eyes, skin, respiratory system
Cancer Site[in animals: pancreas, liver, mammary gland, circulatory sys & skin tumors]										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated/Daily
							**Remove:**When wet or contaminated
							**Change:**Daily
							**Provide:**Eyewash, Quick drench
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Soap wash immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH****At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0339
					  MEDICAL TESTS: 0233

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Chemical Names, Synonyms and Trade Names
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
CAS Numbers
RTECS Numbers
Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
First Aid Procedures Follow NIOSH Facebook
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