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Methylene bisphenyl isocyanate																				Related Pages
Synonyms & Trade Names
			4,4'-Diphenylmethane diisocyanate, MDI, Methylene di-p-phenylene ester of isocyanic acid, Methylene bis(4-phenyl isocyanate)
CAS No.
			101-68-8
	RTECS No.
			NQ9350000
	DOT ID & Guide

FormulaCH2(C6H4NCO)2
	Conversion
			1 ppm = 10.24 mg/m3
	IDLH
			75 mg/m3See: 101688

Exposure Limits
			NIOSH RELTWA 0.05 mg/m3 (0.005 ppm) C 0.2 mg/m3 (0.020 ppm) [10-minute]
					OSHA PEL C 0.2 mg/m3 (0.02 ppm)
	Measurement Methods
			**NIOSH** 5521 , 5522 , 5525;**OSHA** 18
					
					See: NMAM or OSHA Methods
										
Physical Description
			White to light-yellow, odorless flakes.
					[Note: A liquid above 99°F.]													
										
Molecular Weight250.3	
	Boiling Point597°F
	Melting Point99°F
	Solubility0.2%
	Vapor Pressure(77°F): 0.000005 mmHg
	Ionization Potential?											
Specific Gravity1.23 (Solid at 77°F) 1.19 (Liquid at 122°F)	
	Flash Point390°F
	Upper Explosive Limit?
	Lower Explosive Limit?
Combustible Solid
Incompatibilities & Reactivities
			Strong alkalis, acids, alcohol
					[Note: Polymerizes at 450°F.]
Exposure Routes
			inhalation, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, nose, throat; resp sensitization; cough, pulmonary secretions, chest pain, dyspnea (breathing difficulty); asthma
Target Organs
			Eyes, respiratory system
										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet or contaminated
							**Change:**Daily
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Soap wash immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH****Up to 0.5 mg/m3**: (APF = 10) Any supplied-air respirator***Up to 1.25 mg/m3**: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode***Up to 2.5 mg/m3**: (APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece**Up to 75 mg/m3**: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode**Emergency or planned entry into unknown concentrations or IDLH conditions:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having an N100, R100, or P100 filter. Click here for information on selection of N, R, or P filters.Any appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0298
					  MEDICAL TESTS: 0147

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
First Aid Procedures Follow NIOSH Facebook
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