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Isophorone																				Related Pages
Synonyms & Trade Names
			Isoacetophorone, 3,5,5-Trimethyl-2-cyclohexenone, 3,5,5-Trimethyl-2-cyclo-hexen-1-one
CAS No.
			78-59-1
	RTECS No.
			GW7700000
	DOT ID & Guide
			1993 128(combustible liquid, n.o.s.)

FormulaC9H14O
	Conversion
			1 ppm = 5.65 mg/m3
	IDLH
			200 ppmSee: 78591

Exposure Limits
			NIOSH RELTWA 4 ppm (23 mg/m3)
					OSHA PEL TWA 25 ppm (140 mg/m3) See Appendix G
	Measurement Methods
			**NIOSH** 2508 , 2556;**OSHA** 7
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless to white liquid with a peppermint-like odor.													
										
Molecular Weight138.2	
	Boiling Point419°F
	Freezing Point17°F
	Solubility1%
	Vapor Pressure0.3 mmHg
	Ionization Potential9.07 eV											
Specific Gravity0.92	
	Flash Point184°F
	Upper Explosive Limit3.8%
	Lower Explosive Limit0.8%
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Incompatibilities & Reactivities
			Oxidizers, strong alkalis, amines
Exposure Routes
			inhalation, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, nose, throat; headache, nausea, dizziness, lassitude (weakness, exhaustion), malaise (vague feeling of discomfort), narcosis; dermatitis; In Animals: kidney, liver damage
Target Organs
			Eyes, skin, respiratory system, central nervous system, liver, kidneys
										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet or contaminated
							**Change:**No recommendation
							**Provide:**Eyewash
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Soap wash promptly
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH****Up to 40 ppm**: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*(APF = 10) Any supplied-air respirator***Up to 100 ppm**: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode*(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)***Up to 200 ppm**: (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)*(APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode*(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece**Emergency or planned entry into unknown concentrations or IDLH conditions:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0169
					  MEDICAL TESTS: 0123

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
First Aid Procedures Follow NIOSH Facebook
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