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Acetone cyanohydrin																				Related Pages
Synonyms & Trade Names
			Cyanohydrin-2-propanone, 2-Cyano-2-propanol, α-Hydroxyisobutyronitrile, 2-Hydroxy-2-methyl-propionitrile, 2-Methyllactonitrile
CAS No.
			75-86-5
	RTECS No.
			OD9275000
	DOT ID & Guide
			1541 155(stabilized)

FormulaCH3C(OH)CNCH3
	Conversion
			1 ppm = 3.48 mg/m3
	IDLH
			N.D.See: IDLH INDEX

Exposure Limits
			NIOSH RELC 1 ppm (4 mg/m3) [15-minute]
					OSHA PEL none
	Measurement Methods
			**NIOSH** 2506
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless liquid with a faint odor of bitter almond.
					[Note: Forms cyanide in the body.]													
										
Molecular Weight85.1	
	Boiling Point203°F
	Freezing Point-4°F
	SolubilityMiscible
	Vapor Pressure0.8 mmHg
	Ionization Potential?											
Specific Gravity(77°F): 0.93	
	Flash Point165°F
	Upper Explosive Limit12.0%
	Lower Explosive Limit2.2%
Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F.
Incompatibilities & Reactivities
			Sulfuric acid, caustics
					[Note: Slowly decomposes to acetone & HCN at room temperatures; rate is accelerated by an increase in pH, water content, or temperature.]
Exposure Routes
			inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms
			irritation eyes, skin, respiratory system; dizziness, lassitude (weakness, exhaustion), headache, confusion, convulsions; liver, kidney injury; pulmonary edema, asphyxia
Target Organs
			Eyes, skin, respiratory system, central nervous system, cardiovascular system, liver, kidneys, gastrointestinal tract
										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet or contaminated
							**Change:**No recommendation
							**Provide:**Eyewash, Quick drench
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Water flush immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH****Up to 10 ppm**: (APF = 10) Any supplied-air respirator**Up to 25 ppm**: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode**Up to 50 ppm**: (APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece**Up to 250 ppm**: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode**Emergency or planned entry into unknown concentrations or IDLH conditions:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0611

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
First Aid Procedures Follow NIOSH Facebook
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