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Acetic anhydride																				Related Pages
Synonyms & Trade Names
			Acetic acid anhydride, Acetic oxide, Acetyl oxide, Ethanoic anhydride
CAS No.
			108-24-7
	RTECS No.
			AK1925000
	DOT ID & Guide
			1715 137

Formula(CH3CO)2O
	Conversion
			1 ppm = 4.18 mg/m3
	IDLH
			200 ppmSee: 108247

Exposure Limits
			NIOSH RELC 5 ppm (20 mg/m3)
					OSHA PEL TWA 5 ppm (20 mg/m3) See Appendix G
	Measurement Methods
			**NIOSH** 3506;**OSHA** 82 , 102
					
					See: NMAM or OSHA Methods
										
Physical Description
			Colorless liquid with a strong, pungent, vinegar-like odor.													
										
Molecular Weight102.1	
	Boiling Point282°F
	Freezing Point-99°F
	Solubility12%
	Vapor Pressure4 mmHg
	Ionization Potential10.00 eV											
Specific Gravity1.08	
	Flash Point120°F
	Upper Explosive Limit10.3%
	Lower Explosive Limit2.7%
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
Incompatibilities & Reactivities
			Water, alcohols, strong oxidizers (especially chromic acid), amines, strong caustics
					[Note: Corrosive to iron, steel & other metals. Reacts with water to form acetic acid.]
Exposure Routes
			inhalation, ingestion, skin and/or eye contact
Symptoms
			conjunctivitis, lacrimation (discharge of tears), corneal edema, opacity, photophobia (abnormal visual intolerance to light); nasal, pharyngeal irritation; cough, dyspnea (breathing difficulty), bronchitis; skin burns, vesiculation, sensitization dermatitis
Target Organs
			Eyes, skin, respiratory system
										
Personal Protection/Sanitation
			(See protection codes) **Skin:**Prevent skin contact
							**Eyes:**Prevent eye contact
							**Wash skin:**When contaminated
							**Remove:**When wet or contaminated
							**Change:**No recommendation
							**Provide:**Eyewash, Quick drench
	First Aid
			(See procedures)**Eye:**Irrigate immediately
							**Skin:**Water flush immediately
							**Breathing:**Respiratory support
							**Swallow:**Medical attention immediately
Respirator Recommendations
			**NIOSH/OSHA****Up to 125 ppm**: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode£(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)£**Up to 200 ppm**: (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)£(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece**Emergency or planned entry into unknown concentrations or IDLH conditions:** (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus**Escape:** (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus
				Important additional information about respirator selection
See also
			INTRODUCTION
					  ICSC CARD: 0209

			
							

			Page last reviewed:  October 30, 2019						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Pocket Guide to Chemical Hazards
Introduction
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Appendices
A – NIOSH Potential Occupational Carcinogens
B – Thirteen OSHA-Regulated Carcinogens
C – Supplementary Exposure Limits
D – Substances with No Established RELs
E – OSHA Respirator Requirements for Selected Chemicals
F – Miscellaneous Notes
G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
Type C & CE – Definitions for Type C and Type CE Respirators
Personal Protection and Sanitation Codes
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