62650 Federal Register / Vol. 72, No. 214 / Tuesday, November 6, 2007 / Notices 

Regional and Community Bank Group) 

101 Market Street, San Francisco, 

California 94105–1579: 

1. Palomar Enterprises, LLC; to 

become a bank holding company by 

acquiring 18.3 percent of the voting 

shares of Farmers & Merchants Bank of 

Long Beach, both of Long Beach, 

California. 

Board of Governors of the Federal Reserve 

System, November 1, 2007. 

Robert deV. Frierson, 

Deputy Secretary of the Board. 

[FR Doc. E7–21753 Filed 11–5–07; 8:45 am] 

BILLING CODE 6210–01–S 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Secretary’s Advisory Committee on 

Genetics, Health, and Society 

AGENCY: Office of the Secretary, HHS. 

ACTION: Request for public comment on 

a draft report on the oversight of genetic 

testing. 

SUMMARY: The Secretary’s Advisory 

Committee on Genetics, Health, and 

Society (SACGHS) is requesting public 

comment on a draft report on the 

oversight of genetic testing. 

DATES: Written or electronic comments 

should be submitted between November 

5, 2007 and December 21, 2007. 

ADDRESSES: Comments should be 

e-mailed to SACGHS in care of Cathy 

Fomous, PhD, at cfomous@od.nih.gov. 

Comments can also be mailed or faxed 

to Dr. Fomous’s attention at the NIH 

Office of Biotechnology Activities, 6705 

Rockledge Drive, Suite 700, Bethesda, 

MD, 20892 or fax number 301–496–

9839. 

FOR FURTHER INFORMATION CONTACT: 

Cathy Fomous, PhD, NIH Office of 

Biotechnology Activities, at 

cfomous@od.nih.gov or 6705 Rockledge 

Drive, Suite 700, Bethesda, MD 20892, 

301–496–9838. 

SUPPLEMENTARY INFORMATION: The 

Department of Health and Human 

Services (HHS) established SACGHS to 

serve as a public forum for deliberations 

on the broad range of policy issues 

raised by the development and use of 

genetic technologies and, as warranted, 

to provide advice on these issues. For 

more information about the Committee, 

please visit the Web site: http:// 

www4.od.nih.gov/oba/sacghs.htm. 

In 2004, SACGHS recognized that 

oversight of genetic testing was a highpriority issue that required ongoing 

monitoring. In 2006, SACGHS began an 

in-depth fact-finding process on the 

oversight roles of Federal, State, and 

private sector entities. In March 2007, 

the Office of the Secretary of HHS 

outlined a specific charge to SACGHS to 

focus the Committee’s inquiry. The 

charge reads as follows: 

Undertake the development of a 

comprehensive map of the steps needed for 

evidence development and oversight for 

genetic and genomic tests, with improvement 

of health quality as the primary goal. 

Consider and address the following 

questions: 

• What evidence of harm exists regarding 

genetic tests? Is that harm attributable to 

analytic validity, clinical validity, or clinical 

utility of the tests? If evidence does not exist, 

what threats are not currently being 

addressed? What public health benefits are 

not accruing as quickly as they might? 

• What distinguishes genetic tests from 

other laboratory tests for oversight purposes? 

• What are the existing pathways that 

examine the analytic validity, clinical 

validity, and clinical utility of genetic tests? 

Consider the use of case studies. 

• What organizations are currently 

involved with each of these aspects, and 

what are they doing to address these issues? 

Who should be responsible for each of these 

aspects? 

• What resources (e.g., standards reagents/ 

materials) are needed to develop proficiency 

testing kits or protocols for genetic tests? 

What is currently available in terms of 

proficiency testing kits or protocols for 

genetic tests? What information is provided 

by proficiency testing? Is the current level of 

proficiency testing for genetic tests adequate 

and are the results of such laboratory 

performance assessments sufficiently 

transparent? 

• What are the potential pathways to 

communicate clear information to guide test 

and treatment selection by the provider? 

• What new approaches or models should 

be considered for private and public-private 

sector engagement in demonstrating clinical 

validity and clinical utility for developing 

effectiveness measures of genetic tests in 

clinical practice? 

• Would additional or revised Government 

oversight add value for patients, and if so, 

how and where? 

SACGHS organized a task force to 

explore the questions outlined in the 

Secretary’s charge and gather facts and 

perspectives on how best to address 

them. With the help of the task force, 

SACGHS drafted a report that addresses 

the issues and offers a number of 

recommendations for enhancing the 

oversight of genetic testing in the U.S. 

A copy of the draft report, U.S. System 

of Oversight of Genetic Testing: A 

Response to the Charge of the Secretary 

of HHS, will be available from 

November 5, 2007 to December 21, 2007 

at http://www4.od.nih.gov/oba/sacghs/ 

public_comments.htm. A paper or 

electronic copy also can be obtained 

through the NIH Office of Biotechnology 

Activities at 301–496–9838 or by 

e-mailing Dr. Fomous at 

cfomous@od.nih.gov. 

SACGHS would welcome comments 

on any aspect of the report. In 

particular, SACGHS would appreciate 

input on whether the draft report: (1) 

Fully responds to questions posed by 

the HHS Secretary; (2) proposes 

appropriate remedies to close gaps in 

the current system; and (3) adequately 

anticipates future developments in the 

field of genetics/genomics that may bear 

on the oversight of genetic testing. In 

addition to submitting written 

comments, the public will have an 

opportunity at the SACGHS meeting on 

November 19–20, 2007 to provide 

testimony on this topic. The meeting is 

being held at the Ronald Reagan 

Building, Washington, DC (see http:// 

www4.od.nih.gov/oba/SACGHS/ 

SACGhsMTGIndex.HTM for a meeting 

agenda). All comments received by 

December 21, 2007 will be considered 

by SACGHS in preparing its final draft 

report. Public comments will be 

available for public inspection at the 

NIH Office of Biotechnology Activities 

Monday through Friday between the 

hours of 8:30 a.m. and 5 p.m. 

Dated: October 29, 2007. 

Sarah Carr, 

Executive Secretary, SACGHS. 

[FR Doc. E7–21755 Filed 11–5–07; 8:45 am] 

BILLING CODE 4140–01–P 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Administration for Children and 

Families 

Submission for OMB Review; 

Comment Request 

Title: OCSE–100, State Plan Preprint 

Page; OCSE–21–U4, State Plan 

Transmittal. 

OMB No.: 0970–0017. 

Description: Section 7310 of the 

Deficit Reduction Act of 2005, titled, 

Mandatory Fee for Successful Child 

Support Collection for a Family That 

Has Never Received TANF, amends 

Section 454(6) of the Social Security Act 

(the Act) such that a State child support 

plan must provide for the imposition of 

an annual fee of $25 in each case in 

which an individual has never received 

assistance under a State program funded 

under title IV–A of the Act and for 

whom the State has collected at least 

$500 of support. States will need to 

submit the new State plan preprint 

page, i.e., page 2.5–4, as well as a 

transmittal for the preprint page, in 

order to have an approved State plan. 

mstockstill on PROD1PC66 with NOTICES

Federal Register / Vol. 72, No. 214 / Tuesday, November 6, 2007 / Notices 62651 

The 60-day notice for this 

requirement was originally published in 

the Notice of Proposed Rulemaking 

(NPRM) in the Federal Register on 

January 24, 2007 (72 FR 3093); however, 

because of the October 1, 2006, effective 

date for the mandate that States 

implement and collect a $25 annual fee 

in specified cases, the second notice for 

the State plan preprint page must be 

published prior to the publication of the 

final rule. 

Respondents: State IV-D agencies. 

ANNUAL BURDEN ESTIMATES

Instrument Number of 

respondents 

Number of 

responses per 

respondent 

Average 

burden hours 

per response 

Total burden 

hours 

State Plan (OCSE–100) .................................................................................. 54 1 .25 13.5 

State Plan Transmittal (OCSE–21–U4) ........................................................... 54 1 .25 13.5 

Estimated Total Annual Burden 

Hours: 27. 

Additional Information: Copies of the 

proposed collection may be obtained by 

writing to the Administration for 

Children and Families, Office of 

Administration, Office of Information 

Services, 370 L’Enfant Promenade, SW., 

Washington, DC 20447, Attn: ACF 

Reports Clearance Officer. All requests 

should be identified by the title of the 

information collection. E-mail address: 

infocollection@acf.hhs.gov. 

OMB Comment: OMB is required to 

make a decision concerning the 

collection of information between 30 

and 60 days after publication of this 

document in the Federal Register. 

Therefore, a comment is best assured of 

having its full effect if OMB receives it 

within 30 days of publication. Written 

comments and recommendations for the 

proposed information collection should 

be sent directly to the following: 

Office of Management and Budget, 

Paperwork Reduction Project, Fax: 202–

395–6974, Attn: Desk Officer for the 

Administration for Children and 

Families. 

Dated: October 30, 2007. 

Robert Sargis, 

Reports Clearance Officer. 

[FR Doc. 07–5487 Filed 11–5–07; 8:45 am] 

BILLING CODE 4184–01–M 

DEPARTMENT OF HEALTH AND 

HUMAN SERVICES 

Administration for Children and 

Families 

Submission for OMB Review; 

Comment Request 

Title: Tribal TANF (Temporary 

Assistance for Needy Families) 

Financial Report, Form ACF–196T. 

OMB No. New Collection. 

Description: Tribes use Form ACF–

196T to report expenditures for the 

Tribal TANF grant. Authority to collect 

and report this information is found in 

the Personal Responsibility and Work 

Opportunity Reconciliation Act of 1996 

(PRWORA), Public Law 104–193. Tribal 

entities with approved Tribal plans for 

implementation of the TANF program 

are required by Section 412(h) of the 

Social Security Act to report financial 

data. Form ACF–196T provides for the 

collection of data regarding Federal 

expenditures. Failure to collect this data 

would seriously compromise the 

Administration for Children and 

Families’ (ACF) ability to monitor 

expenditures. This information is also 

used to estimate outlays and may be 

used to prepare ACF budget 

submissions to Congress. Financial 

management of the program would be 

seriously compromised if the 

expenditure data were not collected. 

45 CFR Part 286 Subpart E requires 

the strictest controls on funding 

requirements, which necessities review 

of documentation in support of Tribal 

expenditures for reimbursement. 

Comments received from previous 

efforts to implement a similar Tribal 

TANF report Form ACF–196T were 

used to guide ACF in the development 

of the product presented with this 

submittal. 

Respondents: All Tribal TANF 

Agencies 

ANNUAL BURDEN ESTIMATES

Instrument Number of 

respondents 

Number of 

responses per 

respondent 

Average 

burden hours 

per response 

Total burden 

hours 

ACF–196T ........................................................................................................ 56 4 8 1,792 

Estimated Total Annual Burden 

Hours: 1,792. 

Additional Information: Copies of the 

proposed collection may be obtained by 

writing to the Administration for 

Children and Families, Office of 

Administration, Office of Information 

Services, 370 L’Enfant Promenade, SW., 

Washington, DC 20447, Attn: ACF 

Reports Clearance Officer. All requests 

should be identified by the title of the 

information collection. E-mail address: 

infocollection@acf.hhs.gov. 

OMB Comment: OMB is required to 

make a decision concerning the 

collection of information between 30 

and 60 days after publication of this 

document in the Federal Register. 

Therefore, a comment is best assured of 

having its full effect if OMB receives it 

within 30 days of publication. Written 

comments and recommendations for the 

proposed information collection should 

be sent directly to the following: 

Office of Management and Budget, 

Paperwork Reduction Project, Fax: 202–

395–6974, Attn: Desk Officer for the 

Administration for Children and 

Families. 

Dated: October 30, 2007. 

Robert Sargis, 

Reports Clearance Officer. 

[FR Doc. 07–5488 Filed 11–5–07; 8:45 am] 

BILLING CODE 4184–01–M 

mstockstill on PROD1PC66 with NOTICES