EXHIBIT 12

ANGIOTECH

RATIO OF EARNINGS TO FIXED CHARGES



|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|--------------------------------------------------------------------------------- |  | ----------------------- | ------ |  | ---- | - | ------- | ---- |  | - | -------- | --- |  | ---- | ------- | - |  | - | ------- | ---
|                                                                                  |  | Year Ended December 31, |       
|                                                                                  |  | 2006                    |        |  | 2007 |   |         | 2008 |  |   | 2009     |     |  | 2010 |        
|                                                                                  |  | (Dollars in Thousands)  |       
|Earnings:                                                                         |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Pre-tax income (loss) from continuing operations                                  |  | $                       | 20,115 |  |      | $ | (70,592 | )    |  | $ | (754,068 | )   |  | $    | (16,831 | ) |  | $ | (66,885 | )  
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Total Earnings                                                                    |  | $                       | 20,115 |  |      | $ | (70,592 | )    |  | $ | (754,068 | )   |  | $    | (16,831 | ) |  | $ | (66,885 | )  
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Fixed Charges:                                                                    |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Interest expense and amortization of capitalized expenses related to indebtedness |  | $                       | 35,502 |  |      | $ | 51,748  |      |  | $ | 44,490   |     |  | $    | 38,039  |   |  | $ | 40,258  |    
|Interest within rent expense                                                      |  | $                       | 700    |  |      | $ | 800     |      |  | $ | 1,167    |     |  | $    | 1,067   |   |  | $ | 1,100   |    
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Total Fixed Charges                                                               |  | $                       | 36,202 |  |      | $ | 52,548  |      |  | $ | 45,657   |     |  | $    | 39,106  |   |  | $ | 41,358  |    
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Pre-tax income (loss) from continuing operations plus fixed charges               |  | $                       | 56,317 |  |      | $ | (18,044 | )    |  | $ | (708,411 | )   |  | $    | 22,275  |   |  | $ | (25,527 | )  
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Ratio of Earnings to Fixed Charges                                                |  |                         | 1.6    |  |      |   |        | (1)  |  |   |         | (1) |  |      | 0.6     |   |  |   |        | (1)
|                                                                                  |  |                         |        |  |      |   |         |      |  |   |          |     |  |      |         |   |  |   |         |    
|Dollar amount of deficiency                                                       |  |                         | n/a    |  |      | $ | 70,592  |      |  | $ | 754,068  |     |  | $    | 16,831  |   |  | $ | 66,885  |    



|(1) | Our earnings during this period were insufficient to cover fixed charges and, accordingly, ratios are not presented.
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