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p-tert-Butyltoluene																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 98–51–1
**NIOSH REL:** 10 ppm (60 mg/m3) TWA, 20 ppm (120 mg/m3) STEL
**Current OSHA PEL:** 10 ppm (60 mg/m3) TWA
**1989 OSHA PEL:** 10 ppm (60 mg/m3) TWA, 20 ppm (120 mg/m3) STEL
**1993-1994 ACGIH TLV:** 1 ppm (6.1 mg/m3) TWA
**Description of Substance:** Colorless liquid with a distinct aromatic odor, somewhat like gasoline.
**LEL:** . . Unknown
**Original (SCP) IDLH:** 1,000 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the female rat 1-hour LC50 of 934 ppm reported by Hine et al. [1954].
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**Rat RatRatRatMouse
    Hine et al. 1954 Hine et al. 1954Hine et al. 1954Hine et al. 1954Hine et al. 1954
    934 734248165248
    ----- --------------------
    1 hr 2 hr4 hr8 hr4 hr
    1,168 ppm (1.25) 1,174 ppm (1.6)496 ppm (2.0)413 ppm (2.5)496 ppm (2.0)
    117 ppm 117 ppm50 ppm41 ppm50 ppm
 **Other animal data:** RD50 (mouse), 360 ppm [Nielsen and Alarie 1982].
 **Human data:** Giddiness and altered respiration have been reported in volunteers exposed to 160 ppm for 15 minutes [Hine et al. 1954].
 
 **Revised IDLH:** 100 ppm **Basis for revised IDLH:** The revised IDLH for p-tert-butyltoluene is 100 ppm based on acute inhalation toxicity data in humans [Hine et al. 1954].
**REFERENCES:**
1. Hine CH, Ungar H, Anderson HH, Kodama JK, Critchlow JK, Jacobsen NW [1954]. Toxicological studies on p-tertiary-butyltoluene. AMA Arch Ind Hyg Occup Med *9*:227-244.
2. Nielsen GD, Alarie Y [1982]. Sensory irritation, pulmonary irritation, and respiratory stimulation by airborne benzene and alkylbenzenes: prediction of safe industrial exposure levels and correlation of their thermodynamic properties. Toxicol Appl Pharmacol *65*:459-477.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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