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Oxalic acid																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 144–62–7
**NIOSH REL:** 1 mg/m3 TWA, 2 mg/m3 STEL
**Current OSHA PEL:** 1 mg/m3 TWA
**1989 OSHA PEL:** 1 mg/m3 TWA, 2 mg/m3 STEL
**1993-1994 ACGIH TLV:** 1 mg/m3 TWA, 2 mg/m3 STEL
**Description of substance:** Colorless, odorless powder or granular solid.
**LEL**: . Unknown
**Original (SCP) IDLH:** 500 mg/m3
**Basis for original (SCP) IDLH:** The chosen IDLH has been calculated from the total oral lethal dose for man of 5 grams [ACGIH 1971].
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
Lethal dose data:


**Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Dog
    Flury & Zernik 1935
    oral
    -----
    1,000
    7,000 mg/m3
    700 mg/m3Rat
    Shtabsky & Shatinskaya 1985
    ?
    -----
    1,400
    9,800 mg/m3
    980 mg/m3Rat
    Vernot et al. 1977
    oral
    -----
    7,500
    52,500 mg/m3
    5,250 mg/m3**Human data:** It has been reported that the lethal oral dose is 15 to 30 grams [Webster 1930]. [Note: An oral dose of 15 to 30 grams is equivalent to a 30-minute exposure to 10,000 to 20,000 mg/m3 assuming a 50 liter per minute breathing rate and 100% absorption.]
 
 **Revised IDLH:** 500 mg/m3 [Unchanged] **Basis for revised IDLH:** No inhalation toxicity data are available on which to base an IDLH for oxalic acid. Therefore, based on acute oral toxicity data in humans [Webster 1930] and animals [Flury and Zernik 1935], the original IDLH for oxalic acid (500 mg/m3) is not being revised at this time.**REFERENCES:**
1. ACGIH [1971]. Oxalic acid. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 193.
2. Flury F, Zernik F [1935]. Zusammenstellung der toxischen und letalen dosen für die gebräuchlichsten gifte und versuchstiere. Abder Hand Biol Arbeitsmethod *4*:1289-1422 (in German).
3. Shtabsky BM, Shatinskaya EG [1985]. Evaluation of cumulative properties of toxic chemicals from the subchronic experiment. Gig Sanit *50*(3):57-60 (in Russian).
4. Vernot EH, MacEwen JD, Haun CC, Kinkead FR [1977]. Acute toxicity and skin corrosion data for some organic and inorganic compounds and aqueous solutions. Toxicol Appl Pharmacol *42*:417-423.
5. Webster RW [1930]. Legal medicine and toxicology. Philadelphia, PA: W.B. Saunders.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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