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1,1,2-Trichloroethane																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 79–00–5
**NIOSH REL:** 10 ppm (45 mg/m3) TWA [skin]; NIOSH considers 1,1,2-trichloroethane to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990].
**Current OSHA PEL:** 10 ppm (45 mg/m3) TWA [skin]
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 10 ppm (55 mg/m3) TWA [skin]
**Description of substance:** Colorless liquid with a sweet, chloroform-like odor.
**LEL:** . . 6% (10% LEL, 6,000 ppm)
**Original (SCP) IDLH:** 500 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the UCC [1972] report that 500 ppm killed 1 of 6 rats in 4 hours, and 4 of 6 rats in 8 hours.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50**
    **LCLo**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**Cat
    Arch Hyg Bakteriol 1936
    -----
    13,100 mg/m3
    4.5 hr
    4,957 ppm (2.1)
    496 ppmRat
    Carpenter et al. 1949
    -----
    2,000 ppm
    4 hr
    4,000 ppm (2.0)
    400 ppmRat
    UCC 1972
    LC17: 500 ppm
    -----
    4 hr
    1,000 ppm (2.0)
    100 ppmRat
    UCC 1972
    LC67: 500 ppm
    -----
    8 hr
    1,250 ppm (2.5)
    125 ppm**Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 100 ppm **Basis for revised IDLH:** The revised IDLH for 1,1,2-trichloroethane is 100 ppm based on acute inhalation toxicity data in animals [UCC 1972]. [Note: NIOSH recommends as part of its carcinogen policy that the "most protective" respirators be worn for 1,1,2-trichloroethane at concentrations above 10 ppm.]**REFERENCES:**
1. Arch Hyg Bakteriol [1936]; *116*:131 (in German).
2. Carpenter CP, Smyth HF Jr, Pozzani UC [1949]. The assay of acute vapor toxicity and the grading and interpretation of results on 96 chemical compounds. J Ind Hyg Toxicol *31*(6):343-346.
3. UCC [1972]. Toxicology studies: 1,1,2-trichloroethane. New York, NY: Union Carbide Corporation.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
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