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sec-Butyl acetate																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 105–46–4
**NIOSH REL:** 200 ppm (950 mg/m3) TWA
**Current OSHA PEL:** 200 ppm (950 mg/m3) TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 200 ppm (950 mg/m3) TWA
**Description of Substance:** Colorless liquid with a pleasant, fruity odor.
**LEL:** . . 1.7% (10% LEL, 1,700 ppm)
**Original (SCP) IDLH:** 10,000 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on an analogy with n-butyl acetate which has an IDLH of 10,000 ppm.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Animal data:** None relevant for use in determining the revised IDLH.
**Human data:** The vapor of sec-butyl acetate is reportedly less irritating than that of n-butyl acetate [Richmond and Pagnotto 1965].

**Revised IDLH:** 1,700 ppm [LEL] **Basis for revised IDLH:** Based on health considerations and an analogy to n-butyl acetate [Richmond and Pagnotto 1965], a value of about 2,500 ppm would have been appropriate for sec-butyl acetate. However, the revised IDLH for sec-Butyl acetate is 1,700 ppm based strictly on safety considerations (i.e., being 10% of the lower explosive limit of 1.7%).
**REFERENCE:**
1. Richmond M, Pagnotto LD [1965]. Comparative toxicity of selective acetate esters. Unpublished data. [From: ACGIH [1991]. sec-Butyl acetate. In: Documentation of the threshold limit values and biological exposure indices. 6th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 166.]

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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