Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link


Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
					Search
		×
			NIOSH
			NIOSH
				All CDC
				Submit
			For a full list of topics:A-Z Index
			Advanced Search
		Advanced Search


The National Institute for Occupational Safety and Health (NIOSH)


Facebook
        Twitter
        LinkedIn
        Syndicate





Ethyl chloride																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 75–00–3
**NIOSH REL:** Handle with caution in the workplace.
**Current OSHA PEL:** 1,000 ppm (2,600 mg/m3) TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 1,000 ppm (2,640 mg/m3) TWA
**Description of Substance:** Colorless gas or liquid (below 54 F) with a pungent, ether-like odor.
**LEL:**. . 3.8% (10% LEL, 3,800 ppm)
**Original (SCP) IDLH:** 20,000 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on human exposure data reported by Davidson [1926] in which 13,000 ppm caused no difficulty in walking or balancing after 21 minutes, but 19,000 ppm caused weak analgesia and slight dizziness after 12 minutes.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived** **value**Rat MouseG. pig
    Izmerov et al. 1982 Izmerov et al. 1982Sayers and Yant 1929
    59,701 54,478-----
    ----- -----40,000
    2 hr 2 hr45 min
    95,522 ppm (1.6) 87,164 ppm (1.6)45,600 ppm (1.14)
    9,550 ppm 8,716 ppm4,560 ppm
 **Human data:** It has been reported that 13,000 ppm for 21 minutes caused no difficulty in walking or balancing but 19,000 ppm caused weak analgesia and slight dizziness after 12 minutes [Davidson 1926].
 
 **Revised IDLH:** 3,800 ppm [LEL] **Basis for revised IDLH:** Based on health considerations and acute inhalation toxicity data in humans [Davidson 1926], a value of about 13,000 ppm would have been appropriate. However, the revised IDLH for ethyl chloride is 3,800 ppm based strictly on safety considerations (i.e., being 10% of the lower explosive limit of 3.8%).
**REFERENCES:**
1. Davidson BM [1926]. Studies of intoxication. V. The action of ethyl chloride. J Pharmacol Exp Ther *26*:37-42.
2. Izmerov NF, Sanotsky IV, Sidorov KK [1982]. Toxicometric parameters of industrial toxic chemicals under single exposure. Moscow, Russia: Centre of International Projects, GKNT, p. 66.
3. Sayers RR, Yant VP [1929]. Physiological response attending exposure to vapors of methyl bromide, methyl chloride, ethyl bromide and ethyl chloride. Washington, DC: U.S. Government Printing Office, Treasury Department, U.S. Public Health Service, Public Health Bulletin *185*:1-56.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
Pinterest
Twitter
YouTube
 NIOSH Homepage NIOSH A-Z
Workplace Safety & Health Topics
Publications and Products
Programs
Contact NIOSH


About CDC
					Contact Us
					800-232-4636
 Facebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat
 CONTACT CDC
				Contact Us
							Call 800-232-4636
							Email Us
			ABOUT CDC
				About CDC
							Jobs
							Funding
			POLICIES
				Accessibility
							External Links
							Privacy
							Policies
							No Fear Act
							FOIA
							OIG
							Nondiscrimination
							Vulnerability Disclosure Policy
			CONNECT WITH US
				Facebook
								Twitter
								Instagram
								LinkedIn
							Youtube
								Pinterest
								Snapchat
								Email
			LANGUAGES
				Español
							繁體中文
							Tiếng Việt
							한국어
							Tagalog
							Русский
							العربية
							Kreyòl Ayisyen
							Français
							Polski
							Português
							Italiano
							Deutsch
							日本語
							فارسی
							English


U.S. Department of Health & Human Services
			Accessibility
			External Links
			Privacy
			Policies
			No Fear Act
			FOIA
			Nondiscrimination
			OIG
			Vulnerability Disclosure Policy
			USA.gov


Exit Notification/Disclaimer Policy Close
 Links with this icon  indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
					Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
					You will be subject to the destination website's privacy policy when you follow the link.
					CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Website Disclaimers
 Cancel Continue