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Ethylamine																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 75–04–7
**NIOSH REL:** 10 ppm (18 mg/m3) TWA
**Current OSHA PEL:** 10 ppm (18 mg/m3) TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 5 ppm (9.2 mg/m3) TWA, 15 ppm (27.6 mg/m3) STEL
**Description of Substance:** Colorless gas or water-white liquid (below 62 F) with an ammonia-like odor.
**LEL:**. . 3.5% (10% LEL, 3,500 ppm)
**Original (SCP) IDLH:** 4,000 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the UCC [1958] report that a 4-hour exposure to 4,000 ppm killed 1 of 6 rats.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived** **value**Rat MammalRat
    Hine et al. 1960 Kulagina 1975UCC 1958
    ----- 1,230-----
    3,000 -----4,000
    4 hr ?4 hr
    6,000 ppm (2.0) ?8,000 ppm (2.0)
    600 ppm ?800 ppm
 **Lethal dose data:**
 
 **Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Rat
    UCC 1958
    oral
    400
    -----
    1,497 ppm
    150 ppm
 **Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 600 ppm **Basis for revised IDLH:** The revised IDLH for ethylamine is 600 ppm based on acute inhalation toxicity data in animals [Hine et al. 1960; UCC 1958].
**REFERENCES:**
1. Hine CH, Kodama JK, Guzman RJ, Loquvam GS [1960]. The toxicity of allylamines. Arch Environ Health *1*:343-352.
2. Kulagina NK [1975]. Dependence of biological activity of aliphatic hydrocarbons on their chemical structure and physical-chemical properties. Toksikol Nov Prom Khim Vesh *14*:80-90 (in Russian).
3. Smyth HF Jr, Carpenter CP, Weil CS, Pozzani UC [1954]. Range-finding toxicity data: list V. AMA Arch Ind Hyg Occup Med *10*:61-68.
4. UCC [1958]. Toxicology studies: ethyl amine. New York, NY: Union Carbide Corporation.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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