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Perchloryl fluoride																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 7616–94–6
**NIOSH REL:** 3 ppm (14 mg/m3) TWA, 6 ppm (28 mg/m3) STEL
**Current OSHA PEL:** 3 ppm (13.5 mg/m3) TWA
**1989 OSHA PEL:** 3 ppm (14 mg/m3) TWA, 6 ppm (28 mg/m3) STEL
**1993-1994 ACGIH TLV:** 3 ppm (13 mg/m3) TWA, 6 ppm (25 mg/m3) STEL
**Description of substance:** Colorless gas with a characteristic, sweet odor.
**LEL:** . . Nonflammable Gas
**Original (SCP) IDLH:** 385 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the rat 4-hour LC50 of 385 ppm [Greene et al. 1960 cited by ACGIH 1971].
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50 (ppm)**
    **LCLo (ppm)**
    **Time**
    **Adjusted 0.5-hr LC (CF)**
    **Derived value**Rat RatMouseDog
    Dost et al. 1974 Greene et al. 1960Greene et al. 1960Jacobson 1958
    ----- 385630-----
    2,000 ----------451
    40 min 4 hr4 hr4 hr
    2,200 ppm (1.1) 770 ppm (2.0)1,260 ppm (2.0)902 ppm (2.0)
    220 ppm 77 ppm126 ppm90 ppm**Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 100 ppm **Basis for revised IDLH:** The revised IDLH for perchloryl fluoride is 100 ppm based on acute inhalation toxicity data in animals [Greene et al. 1960; Jacobson 1958].**REFERENCES:**
1. ACGIH [1971]. Perchloryl fluoride. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 202-203.
2. Dost FN, Reed DJ, Smith VN, Wang CH [1974]. Toxic properties of chlorine trifluoride. Toxicol Appl Pharmacol *27*:527-536.
3. Greene EA, Colbourn JL, Donati E, Weeks MH [1960]. The inhalation toxicity of perchloryl fluoride. Army Chemical Center, Maryland: U.S. Army Chemical Research and Development Laboratories, Technical Report No. CRDLR 3010, p. 9.
4. Jacobson KH [1958]. Transactions of the Symposium on Health Hazards of Military Chemicals. Army Chemical Center, MD: Directorate of Medical Research, U.S. Army Chemical Warfare Laboratories, CWL Special Publication 2-10.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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