Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link


Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
					Search
		×
			NIOSH
			NIOSH
				All CDC
				Submit
			For a full list of topics:A-Z Index
			Advanced Search
		Advanced Search


The National Institute for Occupational Safety and Health (NIOSH)


Facebook
        Twitter
        LinkedIn
        Syndicate





2-Diethylaminoethanol																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 100–37–8
**NIOSH REL:** 10 ppm (50 mg/m3) TWA [skin]
**Current OSHA PEL:** 10 ppm (50 mg/m3) TWA [skin]
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 10 ppm (48 mg/m3) TWA [skin]
**Description of Substance:** Colorless liquid with a nauseating, ammonia-like odor.
**LEL:**. . Unknown
**Original (SCP) IDLH:** 500 ppm
**Basis for original (SCP) IDLH:** No useful data on acute inhalation toxicity are available on which to base the IDLH for diethylaminoethanol. The chosen IDLH is based on the following statements by Cornish [1965]: “exposure of rats to 500 ppm, 6 hours daily for 5 days, resulted in severe weight loss and high mortality. Daily exposure at 200 ppm resulted in the death of 7 of 50 rats during the first month. A single human exposure for a few seconds to a level well below 200 ppm resulted in nausea and vomiting.”
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived** **value**Rat Mouse
    Lomonova 1970 Lomonova 1970
    924 1,027
    ----- -----
    4 hr ?
    1,848 ppm (2.0) ?
    185 ppm ?
 **Lethal dose data:**
 
 **Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Rat
    Smyth and Carpenter 1944
    oral
    1,300
    -----
    1,869 ppm
    187 ppm
 **Human data:** A very short exposure (<30 seconds) to a concentration estimated to be less than 100 ppm has resulted in nausea and vomiting within 5 minutes; other persons in the same room also complained of the nauseating odor but did not become ill [Cornish 1965].
 
 **Revised IDLH:** 100 ppm **Basis for revised IDLH:** The revised IDLH for 2-diethylaminoethanol is 100 ppm based on acute inhalation toxicity data in humans [Cornish 1965].
**REFERENCES:**
1. Cornish HH [1965]. Oral and inhalation toxicity of 2-diethylaminoethanol. Am Ind Hyg Assoc J *26*:479-484.
2. Lomonova GV [1970]. Toxicology data on dimethylethanolamine and diethylethanolamine. Gig Tr Prof Zabol *14*(11):52-53 (translated).
3. Smyth HF Jr, Carpenter CP [1944]. The place of the range-finding test in the industrial toxicology laboratory. J Ind Hyg Toxicol *26*:269-273.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
Pinterest
Twitter
YouTube
 NIOSH Homepage NIOSH A-Z
Workplace Safety & Health Topics
Publications and Products
Programs
Contact NIOSH


About CDC
					Contact Us
					800-232-4636
 Facebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat
 CONTACT CDC
				Contact Us
							Call 800-232-4636
							Email Us
			ABOUT CDC
				About CDC
							Jobs
							Funding
			POLICIES
				Accessibility
							External Links
							Privacy
							Policies
							No Fear Act
							FOIA
							OIG
							Nondiscrimination
							Vulnerability Disclosure Policy
			CONNECT WITH US
				Facebook
								Twitter
								Instagram
								LinkedIn
							Youtube
								Pinterest
								Snapchat
								Email
			LANGUAGES
				Español
							繁體中文
							Tiếng Việt
							한국어
							Tagalog
							Русский
							العربية
							Kreyòl Ayisyen
							Français
							Polski
							Português
							Italiano
							Deutsch
							日本語
							فارسی
							English


U.S. Department of Health & Human Services
			Accessibility
			External Links
			Privacy
			Policies
			No Fear Act
			FOIA
			Nondiscrimination
			OIG
			Vulnerability Disclosure Policy
			USA.gov


Exit Notification/Disclaimer Policy Close
 Links with this icon  indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
					Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
					You will be subject to the destination website's privacy policy when you follow the link.
					CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Website Disclaimers
 Cancel Continue