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Vinyl toluene																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 25013–15–4
**NIOSH REL:** 100 ppm (480 mg/m3) TWA
**Current OSHA PEL:** 100 ppm (480 mg/m3) TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 50 ppm (242 mg/m3) TWA, 100 ppm (483 mg/m3) STEL
**Description of substance:** Colorless liquid with a strong, disagreeable odor.
**LEL:** . . 0.8% (10% LEL, 800 ppm)
**Original (SCP) IDLH:** 5,000 ppm
**Basis for original (SCP) IDLH:** Because no data on acute inhalation toxicity are available on which to base an IDLH for vinyl toluene, the chosen IDLH has been based on an analogy with styrene, which has an IDLH of 5,000 ppm.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**Mouse
    Krynskaya et al. 1969
    615
    -----
    4 hr
    1,230 ppm (2.0)
    123 ppm**Lethal dose data:**
 
 **Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Mouse Rat
    Krynskaya et al. 1969 Yang & Mackerer 1990
    oral oral
    ----- -----
    3,160 2,255
    4,505 ppm 3,215 ppm
    451 ppm 322 ppm**Other animal data:** RD50 (mouse), 16.4 ppm [DeCeaurriz et al. 1981].
 **Human data:** Although eye and nasal irritation have been noted, 400 ppm has been considered a safe concentration [ACGIH 1986].
 
 **Revised IDLH:** 400 ppm **Basis for revised IDLH:** The revised IDLH for vinyl toluene is 400 ppm based on acute inhalation toxicity data in humans [ACGIH 1986]. This may be a conservative value due to the lack of relevant acute toxicity data for workers exposed to concentrations above 400 ppm.**REFERENCES:**
1. ACGIH [1986]. Vinyl toluene. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 275-276.
2. DeCeaurriz JC, Micillino JC, Bonnet P, Guenier JP [1981]. Sensory irritation caused by various industrial airborne chemicals. Toxicol Lett *9*:137-143.
3. Krynskaya IL, Petrova LI, Guricheva ZG, Robachevskaya EG, Bukevich GM [1969]. Toxicity of vinyltoluene and its determination in air. Gig Sanit *34*(7-9):334-339 (translated).
4. Yang JJ, Mackerer CR [1990]. Acute toxicologic testing of para-methylstyrene using rats and dogs. J Am Coll Toxicol, Part B *1*:77 [Abstract].

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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