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Ammonium sulfamate																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 7773-06-0
**NIOSH REL:** 10 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA
**Current OSHA PEL:**15 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA
**1989 OSHA PEL:** 10 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA
**1993-1994 ACGIH TLV** 10 mg/m3 TWA
**Description of substance:** Colorless to white crystalline, odorless solid.
**LEL:** Noncombustible Solid
**Original (SCP) IDLH:** 5,000 mg/m3
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the rat intraperitoneal LDLO of 800 mg/kg cited by NIOSH [1976] from Ambrose [1943]. This compound has a low toxicity.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal dose data:**
Species
    Reference
    Route
    LD50(mg/kg)
    LDLo(mg/kg)
    Adjusted LD
    Derived ValueRat
    Ball 1956
    oral
    2,000
    -----
    14,000 mg/m3
    1,400 mg/m3Mouse
    Gig Tr Prof Zabol 1963
    oral
    3,100
    -----
    21,700 mg/m3
    2,170 mg/m3Rat
    Lehman 1951
    oral
    3,900
    -----
    27,300 mg/m3
    2,730 mg/m3Mouse
    Lehman 1951
    oral
    5,760
    -----
    40,320 mg/m3
    4,032 mg/m3**Human data:** None relevant for use in determining the revised IDLH.
 **Revised IDLH:** 1,500 mg/m3Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ammonium sulfamate. Therefore, the revised IDLH for ammonium sulfamate is 1,500 mg/m3 based on the acute oral toxicity data in animals [Ball 1956]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.**REFERENCES:**
Ambrose AM [1943]. Studies of the physiological effects of sulfamic acid and ammonium sulfamate. J Ind Hyg Toxicol *25*:26.
Ball WL [1956]. Threshold limits for pesticides. AMA Arch Ind Health *14*:178-185.
Gig Tr Prof Zabol [1963]; *7*(5):56-57 (in Russian).
Lehman AJ [1951]. Chemicals in foods: a report to the Association of Food and Drug Officials on current developments. Part II. Pesticides. Q Bulletin Assoc Food Drug Off U.S. *15*(4):122-125.
NIOSH [1976]. WO61250. Sulfamic acid, monoammonium salt. In: Registry of Toxic Effects of Chemical Substances (RTECS) 1976 ed. Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 76-191, p. 1111.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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