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Dimethylphthalate																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 131–11–3
**NIOSH REL:** 5 mg/m3 TWA
**Current OSHA PEL:** 5 mg/m3 TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 5 mg/m3 TWA
**Description of Substance:** Colorless, oily liquid with a slight, aromatic odor.
**LEL**(@358 F): 0.9% (10% LEL(@358 F), 11,300 mg/m3)
**Original (SCP) IDLH:** 9,300 mg/m3
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the statement by Spector [1956] that 9,300 mg/m3 was a lethal concentration for the cat [Eller 1937].
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50**
    **LCLo**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived** **value**Cat
    Eller, 1937
    -----
    9,630 mg/m3
    6 hr
    22,149 mg/m3 (2.3)
    2,215 mg/m3
 **Lethal dose data:**
 
 **Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Rat RabbitG. pigRatMouseRabbitG. pig
    Lehman 1955 Lehman 1955Lehman 1955Timofeevskaia et al. 1963Timofeevskaia et al. 1963Woodard and Hagan 1948Woodard and Hagan 1948
    oral oraloraloraloraloraloral
    6,900 1,0002,4006,8006,8004,4002,400
    ----- ------------------------------
    48,300 mg/m37,000 mg/m316,800 mg/m347,600 mg/m347,600 mg/m330,800 mg/m316,800 mg/m3
    4,830 mg/m3700 mg/m31,680 mg/m34,760 mg/m34,760 mg/m33,080 mg/m31,680 mg/m3
 **Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 2,000 mg/m3**Basis for revised IDLH:** The revised IDLH for dimethylphthalate is 2,000 mg/m3 based on acute inhalation toxicity data in animals [Eller 1937]. [Note: Due to its low volatility, this concentration could only be reached at elevated temperatures or if the liquid droplets become airborne as in a mist.]
**REFERENCES:**
1. Eller [1937]. Doctoral dissertation. Wurzburg, Germany: Julius Maximillian University (in German). [From Spector WS, ed. [1956]. Handbook of toxicology. Vol. I. Acute toxicities. Philadelphia, PA: W.B. Saunders Company, pp. 334-335.]
2. Lehman AJ [1955]. Insect repellents. Q Bulletin Assoc Food Drug Off U.S. *19*:87-90.
3. Spector WS, ed. [1956]. Handbook of toxicology. Vol. I. Acute toxicities. Philadelphia, PA: W.B. Saunders Company, pp. 334-335.
4. Timofeevskaia LA, Ivanova NI, Balinina ES [1963]. Toxicology of o-phthalic acid esters and hygienic reglamentation. Gig Tr Prof Zabol *24*(3):25-27 (in Russian).
5. Woodard G, Hagan EC [1948]. Toxicological investigations of compounds proposed for use as insect repellents. B. Acute oral toxicity. J Pharmacol Exp Ther *93*:26-39.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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