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TEDP																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 3689–24–5
**NIOSH REL:** 0.2 mg/m3 TWA [skin]
**Current OSHA PEL:** 0.2 mg/m3 TWA [skin]
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 0.2 mg/m3 TWA [skin]
**Description of substance:** Pale-yellow liquid with a garlic-like odor.
**LEL** :. . Unknown
**Original (SCP) IDLH:** 35 mg/m3
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the rat oral LD50 of 5 mg/kg [Lehman 1951 cited by ACGIH 1971]. No other useful data are available on which to base the IDLH.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50**
    **LCLo**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**Rat
    Kimmerle & Klimmer 1974
    38 mg/m3
    -----
    4 hr
    76 mg/m3 (2.0)
    7.6 mg/m3Mouse
    Kimmerle & Klimmer 1974
    40 mg/m3
    -----
    4 hr
    80 mg/m3 (2.0)
    8.0 mg/m3**Lethal dose data:**
 
 **Species**
    **Reference**
    **Route**
    **LD50** **(mg/kg)**
    **LDLo** **(mg/kg)**
    **Adjusted LD**
    **Derived value**Mouse
    Kimmerle & Klimmer 1974
    oral
    22
    -----
    154 mg/m3
    15 mg/m3Rabbit
    Kimmerle &Klimmer 1974
    oral
    25
    -----
    175 mg/m3
    18 mg/m3Dog
    Kimmerle & Klimmer 1974
    oral
    5
    -----
    35 mg/m3
    3.5 mg/m3Rat
    Lehman 1951
    oral
    5
    -----
    35 mg/m3
    3.5 mg/m3**Other animal data:** It has been stated that TEDP is an organophosphate pesticide whose toxicity is similar to that of parathion [ACGIH 1991].
 **Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 10 mg/m3 **Basis for revised IDLH:** The revised IDLH for TEDP is 10 mg/m3 based on acute inhalation toxicity data in animals [Kimmerle and Klimmer 1974] and on an analogy with parathion [ACGIH 1991] which has a revised IDLH of 10 mg/m3.**REFERENCES:**
1. ACGIH [1971]. TEDP (tetraethyl dithionopyrophosphate). In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 244-245.
2. ACGIH [1991]. Sulfotep. In: Documentation of the threshold limit values and biological exposure indices. 6th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 1452-1454.
3. Kimmerle G, Klimmer OR [1974]. Acute and subchronic toxicity of sulfotep. Arch Toxicol 33:1-16.
4. Lehman AJ [1951]. Chemicals in foods: A report to the Association of Food and Drug Officials on current developments. Part II. Pesticides. Section II. Dermal Toxicity. Q Bulletin Assoc Food Drug Off U.S. 16(1):3-9.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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