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Benzoyl peroxide																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 94-36-0
**NIOSH REL:** 5 mg/m3 TWA
**Current OSHA PEL:**5 mg/m3 TWA
**1989 OSHA PEL:** Same as current PEL
**1993-1994 ACGIH TLV:** 5 mg/m3 TWA
**Description of Substance:** Colorless to white crystals or a granular powder with a faint, benzaldehyde-like odor.
**LEL:** Unknown
**Original (SCP) IDLH:** 7,000 mg/m3
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the estimated mouse 4-hour LC50 of 700 ppm (7,000 mg/m3) for benzoyl peroxide cited by ACGIH [1971]. However, this concentration is not an actual LC50 value for benzoyl peroxide; it was estimated by ACGIH [1971] by analogy from data concerning LC50 values for other related organic peroxides [Floyd and Stokinger 1958].
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA**
**Lethal concentration data:**
Species
    Reference
    LC50
    LCLo
    Time
    Adjusted 0.5-hr LC (CF)
    Derived Value PPMMouse
    Floyd and Stokinger 1958
    7,000 mg/m3
    -----
    4 hr
    14,000 mg/m3 (2.0)
    1,400 mg/m3**Lethal dose data:**
 Species
    Reference
    Route
    LD50(mg/kg)
    LDLo(mg/kg)
    Adjusted LD
    Derived ValueMouse
    ARCO 1982
    oral
    7,710
    -----
    53,970 mg/m3
    5,397 mg/m3**Human data:** Concentrations of 12 mg/m3 and higher have resulted in pronounced irritation of the nose and throat [Moskowitz and Grabois 1950].
 **Revised IDLH:** 1,500 mg/m3**Basis for revised IDLH:** The revised IDLH for benzoyl peroxide is 1,500 mg/m3 based on acute inhalation toxicity data in animals [Floyd and Stokinger 1958].**REFERENCES:**

ACGIH [1971]. Acetaldehyde. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 23-24.
ARCO [1982]. Toxicology report. 70% aqueous tertiary butyl hydroperoxide: acute toxicity evaluation. Newtown Square, PA: Arco Chemical Company, June 1982.
Floyd EP, Stokinger HE [1958]. Toxicity studies of certain organic peroxides and hydroperoxides. Am Ind Hyg Assoc J *19*:205-212.
Moskowitz S, Grabois B [1950]. Unpublished report sent to ACGIH. Albany, NY: New York State Department of Labor, Division of Industrial Hygiene (November 1950). [From ACGIH [1991]. Benzoyl peroxide. In: Documentation of the threshold limit values and biological exposure indices. 6th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 123-124.]

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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