Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link


Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People
					Search
		×
			NIOSH
			NIOSH
				All CDC
				Submit
			For a full list of topics:A-Z Index
			Advanced Search
		Advanced Search


The National Institute for Occupational Safety and Health (NIOSH)


Facebook
        Twitter
        LinkedIn
        Syndicate





Pentaborane																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 19624–22–7
**NIOSH REL:** 0.005 ppm (0.01 mg/m3) TWA, 0.015 ppm (0.03 mg/m3) STEL
**Current OSHA PEL:** 0.005 ppm (0.01 mg/m3) TWA
**1989 OSHA PEL:** 0.005 ppm (0.01 mg/m3) TWA, 0.015 ppm (0.03 mg/m3) STEL
**1993-1994 ACGIH TLV:** 0.005 ppm (0.013 mg/m3) TWA,
0.015 ppm (0.039 mg/m3) STEL
**Description of substance:** Colorless liquid with a pungent odor like sour milk.
**LEL:** . . 0.42% (10% LEL, 420 ppm)
**Original (SCP) IDLH:** 3 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the mouse 4-hour LC50 of 3 ppm [Jacobson 1958 cited by ACGIH 1971].
**Existing short-term exposure guidelines:** American Industrial Hygiene Association [AIHA 1966] Emergency Exposure Limits (EELs):
5 minute EEL: 25 ppm
15-minute EEL: 8 ppm
30-minute EEL: 4 ppm
60-minute EEL: 2 ppm
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50 (ppm)**
    **LCLo (ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**Mouse RatMouseDogMonkeyRatMouseRatMouseRatMouseRatMouse
    Jacobson 1958 Levinskas et al. 1958Levinskas et al. 1958Weeks et al. 1964Weeks et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964Weir et al. 1964
    3 63.435244674031191511106
    ----- ------------------------------------------------------------
    4 hr 4 hr4 hr15 min2 min5 min5 min15 min15 min30 min30 min1 hr1 hr
    6 ppm (2.0) 12 ppm (2.0)6.8 ppm (2.0)28 ppm (0.79)100 ppm (0.41)37 ppm (0.55)22 ppm (0.55)24 ppm (0.79)15 ppm (0.79)15 ppm (1.0)11 ppm (1.0)13 ppm (1.25)7.5 ppm (1.25)
    0.6 ppm 1.2 ppm0.7 ppm2.8 ppm10 ppm3.7 ppm2.2 ppm2.4 ppm1.5 ppm1.5 ppm1.1 ppm1.3 ppm0.8 ppm**Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 1 ppm **Basis for revised IDLH:** The revised IDLH for pentaborane is 1 ppm based on acute inhalation toxicity data in animals [Jacobson 1958; Levinskas et al. 1958; Weir et al. 1964].**REFERENCES:**
1. ACGIH [1971]. Pentaborane. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 197.
2. AIHA [1966]. Emergency exposure limits. American Industrial Hygiene Association, Toxicology Committee. Am Ind Hyg Assoc J *27*:193-195.
3. Jacobson KH [1958]. Toxicity of borane fuels. In: Transactions of the symposium on health hazards of military chemicals. Army Chemical Center, MD: U.S. Army Chemical Warfare Laboratories, Directorate of Medical Research. CWL Special Publication 2-10, pp. 55-60.
4. Levinskas GJ, Paslian MR, Bleckman WR [1958]. Chronic toxicity of pentaborane vapor. Am Ind Hyg Assoc J *19*:46-53.
5. Weeks MH, Burke DG, Bassett EE, Johnson JR, Christensen MK [1964]. Pentaborane: relationship between inhaled lethal and incapacitating dosages in animals. J Pharmacol Exp Ther *145*:382-385.
6. Weir FW, Seabaugh VM, Mershon MM, Burke DG, Weeks MH [1964]. Short exposure inhalation toxicity of pentaborane in animals. Toxicol Appl Pharmacol *6*:122-131.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
Pinterest
Twitter
YouTube
 NIOSH Homepage NIOSH A-Z
Workplace Safety & Health Topics
Publications and Products
Programs
Contact NIOSH


About CDC
					Contact Us
					800-232-4636
 Facebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat
 CONTACT CDC
				Contact Us
							Call 800-232-4636
							Email Us
			ABOUT CDC
				About CDC
							Jobs
							Funding
			POLICIES
				Accessibility
							External Links
							Privacy
							Policies
							No Fear Act
							FOIA
							OIG
							Nondiscrimination
							Vulnerability Disclosure Policy
			CONNECT WITH US
				Facebook
								Twitter
								Instagram
								LinkedIn
							Youtube
								Pinterest
								Snapchat
								Email
			LANGUAGES
				Español
							繁體中文
							Tiếng Việt
							한국어
							Tagalog
							Русский
							العربية
							Kreyòl Ayisyen
							Français
							Polski
							Português
							Italiano
							Deutsch
							日本語
							فارسی
							English


U.S. Department of Health & Human Services
			Accessibility
			External Links
			Privacy
			Policies
			No Fear Act
			FOIA
			Nondiscrimination
			OIG
			Vulnerability Disclosure Policy
			USA.gov


Exit Notification/Disclaimer Policy Close
 Links with this icon  indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website.
					Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website.
					You will be subject to the destination website's privacy policy when you follow the link.
					CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Website Disclaimers
 Cancel Continue