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Triethylamine																				Related Pages
										May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)
**CAS number:** 121–44–8
**NIOSH REL:** The 1989 OSHA PEL may not be protective to workers.
**Current OSHA PEL:** 25 ppm (100 mg/m3) TWA
**1989 OSHA PEL:** 10 ppm (40 mg/m3) TWA, 15 ppm (60 mg/m3) STEL
**1993-1994 ACGIH TLV:** 5 ppm (12 mg/m3) TWA, 15 ppm (36 mg/m3) STEL
**Description of substance:** Colorless liquid with a strong, ammonia-like odor.
**LEL:** . . 1.2% (10% LEL, 1,200 ppm)
**Original (SCP) IDLH:** 1,000 ppm
**Basis for original (SCP) IDLH:** The chosen IDLH is based on the UCC [1970] report that a 4-hour exposure to 1,000 ppm killed 1 of 6 rats.
**Short-term exposure guidelines:** None developed
**ACUTE TOXICITY DATA:**
**Lethal concentration data:**

**Species**
    **Reference**
    **LC50** **(ppm)**
    **LCLo** **(ppm)**
    **Time**
    **Adjusted 0.5-hr** **LC (CF)**
    **Derived value**G. pig MouseRat
    Carpenter et al. 1948 Izmerov et al. 1982Smyth et al. 1951
    LC33: 1,000 -----LC17: 1,000
    ----- 1,425-----
    4 hr 2 hr4 hr
    2,000 ppm (2.0) 2,280 ppm (1.6)2,000 ppm (2.0)
    200 ppm 228 ppm200 ppm**Other animal data:** RD50 (mouse), 184 ppm [Nielsen and Yamagiwa 1989].
 **Human data:** None relevant for use in determining the revised IDLH.
 
 **Revised IDLH:** 200 ppm **Basis for revised IDLH:** The revised IDLH for triethylamine is 200 ppm based on acute inhalation toxicity data in animals [Carpenter et al. 1948; Izmerov et al. 1982; Nielsen and Yamagiwa 1989; Smyth et al. 1951]. This may be a conservative value due to the lack of acute inhalation toxicity data for workers.**REFERENCES:**
1. Carpenter CP, Smyth HF Jr, Shaffer CB [1948]. The acute toxicity of ethylene imine to small animals. J Ind Hyg Toxicol *30*:2-6.
2. Izmerov NF, Sanotsky IV, Sidorov KK [1982]. Toxicometric parameters of industrial toxic chemicals under single exposure. Moscow, Russia: Centre of International Projects, GKNT, p. 115.
3. Nielsen GD, Yamagiwa M [1989]. Structure-activity relationships of airway irritating aliphatic amines. Receptor activation mechanisms and predicted industrial exposure limits. Chem Biol Interact *71*(2-3):223-244.
4. Smyth HF Jr, Carpenter CP, Weil CS [1951]. Range-finding toxicity data: list IV. AMA Arch Ind Hyg Occup Med *4*:119-122.
5. UCC [1970]. Toxicology studies: triethylamine. New York, NY: Union Carbide Corporation.

			
							
								Page last reviewed:  December 4, 2014						Content
							source: 	National Institute for Occupational Safety and Health NIOSH Publications & Products
Immediately Dangerous To Life or Health (IDLH) Values
Table of IDLH Values
Criteria for Determining IDLH Values
Historical Documentation
Original (SCP) Values
Abbreviations for IDLH Documentation
Abbreviations for Journal Titles Follow NIOSH Facebook
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