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Study Syllabus for Classification of Radiographs of Pneumoconioses						Print
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										Pathology OverviewPathology Basis of Occupational Lung DiseasePulmonary Silicosis
Mixed-Dust Fibrosis
In some industrial settings, such as foundry work or coal mining, the inhalation of free crystalline silica in conjunction with other minerals leads to a characteristic stellate nodule of mixed-dust fibrosis. The stellate nodule, as opposed to the more classical rounded silicotic nodule, has irregular extensions into the adjacent lung parenchyma, producing a “Medusa-head” lesion (Fig. 21). Abundant black pigment and brightly birefringent silicate particles impregnate stellate nodules. Since a mixture of nonsiliceous minerals and/or black pigment is often seen in association with classical silicosis, the determinants for the development of mixed-dust fibrotic nodules are somewhat uncertain [Silicosis and Silicate Disease Committee 1988].
Acute and Accelerated Silicosis
Acute silicosis is characterized pathologically by the filling of alveolar spaces by lipoproteinaceous material that stains red-violet with periodic acid–Schiff stain (Fig. 22). There may be associated diffuse alveolar septal fibrosis and small, cellular, poorly formed silicotic nodules [Silicosis and Silicate Disease Committee 1988; Buechner and Ansari 1969]. In acute silicosis, silica particles may be difficult to visualize with polarized light because of their exceedingly small size. Accelerated silicosis is also a severe progressive form of silicosis caused by inhalation of abundant fine silica particles. The time course of accelerated silicosis is intermediate in duration between acute and chronic silicosis. Cellular silicotic nodules may resemble granulomas in the early stages, with progression to massive conglomerate fibrosis in the later stages of the disease.CHRONIC NODULAR SILICOSISPage 2 of 3LYMPH NODE SILICOSIS
							
					
							Last Reviewed:  April 26, 2023						Source: 	National Institute for Occupational Safety and Health
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        Syndicate homeStudy Syllabus for Classification of Radiographs of Pneumoconioses
Introductionplus icon
Preface
Appreciation to Contributors
Intent of the Self-study Syllbus
Getting Started
Clinical Overviewplus icon
Major Occupational Lung Diseasesplus icon
Pneumoconioses
Central Role of Diagnostic Imagingplus icon
Role of CT
Overview of Nonimaging Clinical Tools in Lung Disease Diagnosis
Appendix A
References
Pathology Overviewplus icon
Pulmonary Silicosis
Coal Workers’ Pneumoconiosis
Asbestos Pleuropulmonary Disease
Pathological-Clinical Correlations
References
Radiograph Classificationplus icon
SUBSET 1 – Radiograph Classification, #1 to #19plus icon
Introduction
Radiograph Identification
Section 1: Image Quality
Section 2: Parenchymal Abnormalities, #1 to #14
Section 3: Pleural Abnormalities, #15 to #19
Section 4: Any Other Abnormalities
Section 5
SUBSET 2 – Radiograph #20 to #27plus icon
Radiograph #20
Radiograph #21
Radiograph #22
Radiograph #23
Radiograph #24
Radiographs #25 to #27
SUBSET 3 – Radiograph #28 to #38plus icon
Radiographs #28 to #30
Radiographs #31 to #32
Radiographs #33 to #35
Radiographs #36 to #38
SUBSET 4 – Radiograph #39 to #46 (Small and Large Opacities)plus icon
Radiographs #39 to #40
Radiographs #41 to #42
Radiographs #43 to #44
Radiograph #45
Radiograph #46
SUBSET 5 – Classifications and Answer Keys, Radiographs #47 to #83
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