U.S. SECURITIES AND EXCHANGE COMMISSION

| (Mark      One)                                                                                                                                                                |   |                                                      |
|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------|-----------------------------------------------------------|
| x                                                                                                                                                                              |   | ANNUAL      REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE |
|                                                                                                                                                                           |   | SECURITIES      EXCHANGE ACT OF 1934                      |
| For      the fiscal year ended June 30, 2008                                                                                                                                   |
| o                                                                                                                                                                              |   | TRANSITION      REPORT UNDER SECTION 13 OR 15(d) OF THE   |
|                                                                                                                                                                           |   | SECURITIES      EXCHANGE ACT OF 1934                      |
| For      the transition period      from                      to |

| Massachusetts(State      or other jurisdiction ofincorporation      or organization)         | 04-2837126(I.R.S.      Employer Identification No.) |
|----------------------------------------------------------------------------------------------|-----------------------------------------------------|
| 107      Audubon Road, Wakefield, Massachusetts(Address      of principal executive offices) | 01880(Zip      Code)                                |

| Title      of each classCommon      Stock, $0.10 par value per share | Name      of each exchange on which registeredAmerican      Stock Exchange |
|----------------------------------------------------------------------|----------------------------------------------------------------------------|

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IGNATURES

| Dated:      October 30, 2008 | Implant      Sciences Corporation |
|------------------------------|-----------------------------------|
|                         | By:                               | /s/      Phillip C. Thomas |
|                         |                              | Phillip      C. ThomasChief      Executive Officer and President |

| Dated:      October 30, 2008 |                                                                                                                                   | /s/      Phillip C. Thomas    |   |
|------------------------------|----------------------------------------------------------------------------------------------------------------------------------------|-------------------------------|--------|
|                         | Phillip      C. ThomasChief      Executive Officer and President(Principal      Executive Officer)                                     |                          |
| Dated:      October 30, 2008 |                                                                                                                                   | /s/      David Eisenhaure     |   |
|                         | David      EisenhaureDirector                                                                                                          |                          |
| Dated:      October 30, 2008 |                                                                                                                                   | /s/      Joseph Levangie      |   |
|                         | Joseph      LevangieDirector                                                                                                           |                          |
| Dated:      October 30, 2008 |                                                                                                                                   | /s/      Michael Szycher, PhD |   |
|                         | Michael      Szycher, PhDDirector                                                                                                      |                          |
| Dated:      October 30,2008  |                                                                                                                                   | /s/      Michael Turmelle     |   |
|                         | Michael      TurmelleDirector                                                                                                          |                          |
| Dated:      October 30, 2008 |                                                                                                                                   | /s/      Glenn D. Bolduc      |   |
|                         | Glenn      D. BolducVice      President and Chief Financial Officer(Principal      Financial Officer and Principal Accounting Officer) |                          |