EXHIBIT 14.2



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



John Stocker



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Greenwood Nominees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary Regular annual payment of part
of directors fees in lieu of cash consideration
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



|1,329 | 
|----- | 



---

|8) | Percentage of issued class
|-- | --------------------------



0.003%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



|80,951 | 
|------ | 



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



|0.198% | 
|------ | 



---

If a director has been granted options by the company please complete the following boxes



17) Date of grant



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries Diane Mellett, 01223 471471
|--- | ----------------------------------------------------------------------------



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



---

SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Peter Garland



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Greenwood Nominees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Regular annual payment of part of directors fees in lieu of cash consideration



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



|2,987 | 
|----- | 



|8) | Percentage of issued class
|-- | --------------------------



|0.007% | 
|------ | 



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



---

|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



43,004



|16) | Total percentage holding of issued class following this notification 0.105%
|--- | ---------------------------------------------------------------------------



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



---

|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries Diane Mellett, 01223 471471
|--- | ----------------------------------------------------------------------------



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Aaron Klug



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



---

|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Greenwood Nominees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Regular annual payment of part of directors fees in lieu of cash consideration



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



1,329



|8) | Percentage of issued class
|-- | --------------------------



0.003%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



---

|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



30,279



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.074%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



---

|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Åke Stavling



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Greenwood Nominees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



---

|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Regular annual payment of part of directors fees in lieu of cash consideration



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



1,107



|8) | Percentage of issued class
|-- | --------------------------



0.002%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



---

|15) | Total holding following this notification
|--- | -----------------------------------------



1,107



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.002%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



---

|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Uwe Bicker



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



As in 2 above



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



---

Regular annual payment of part of directors fees in lieu of cash consideration



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



1,329



|8) | Percentage of issued class
|-- | --------------------------



0.003%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



12) Price per share



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



4,810



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.011%



---

If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



---

SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Paul Nicholson



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



As in 2 above



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Regular annual payment of part of directors fees in lieu of cash consideration



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



1,329



|8) | Percentage of issued class
|-- | --------------------------



0.003%



---

|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



7,093



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.017%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



---

|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Peter Ringrose



---

|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Greenwood Nominees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



(i) Regular annual payment of part of directors fees in lieu of cash consideration (ii)
purchase of shares



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



(i) 862 (ii) 1,065



|8) | Percentage of issued class
|-- | --------------------------



0.004%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



---

|11) | Class of security
|--- | -----------------



|Ordinary | 10p shares
|-------- | ----------



|12) | Price per share
|--- | ---------------



(i) £4.31 (ii) £4.27



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



1,924



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.004%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



---

|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



Peter Chambré



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



---

|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Computershare Trustees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Award of free shares under the Inland Revenue Approved Share Incentive Plan



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



260



|8) | Percentage of issued class
|-- | --------------------------



0.00%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



---

|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



9,789



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.02%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



---

|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



David Glover



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Computershare Trustees Limited



|5) | Please state whether notification relates to a person(s) connected
|-- | ------------------------------------------------------------------

with the Director named in 2 above and identify the connected person(s)



As in 2 above



---

|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Award of free shares under the Inland Revenue Approved Share Incentive Plan



|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



260



|8) | Percentage of issued class
|-- | --------------------------



0.00%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



---

|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



11,789



|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.03%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information
|--- | --------------------------



|24) | Name of contact and telephone number for queries
|--- | ------------------------------------------------



Diane Mellett, 01223 471471



---

|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003



SCHEDULE 11



NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS



|1) | Name of company
|-- | ---------------



Cambridge Antibody Technology



|2) | Name of director
|-- | ----------------



John Aston



|3) | Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an
individual holder if it is a holding of that persons spouse or children under the age of 18 or in respect of a non-beneficial interest
|-- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|4) | Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them (if notified)
|-- | ----------------------------------------------------------------------------------------------------------------------



Computershare Trustees Limited



|5) | Please state whether notification relates to a person(s) connected with the Director named in 2 above and identify the connected person(s)
|-- | ------------------------------------------------------------------------------------------------------------------------------------------



As in 2 above



|6) | Please state the nature of the transaction. For PEP transactions please indicate whether general/single co PEP and if discretionary/non discretionary
|-- | -----------------------------------------------------------------------------------------------------------------------------------------------------



Award of free shares under the Inland Revenue Approved Share Incentive Plan



---

|7) | Number of shares/amount of stock acquired
|-- | -----------------------------------------



260



|8) | Percentage of issued class
|-- | --------------------------



0.00%



|9) | Number of shares/amount of stock disposed
|-- | -----------------------------------------



Nil



|10) | Percentage of issued class
|--- | --------------------------



Nil



|11) | Class of security
|--- | -----------------



Ordinary 10p shares



|12) | Price per share
|--- | ---------------



£4.31



|13) | Date of transaction
|--- | -------------------



21 November 2003



|14) | Date company informed
|--- | ---------------------



21 November 2003



|15) | Total holding following this notification
|--- | -----------------------------------------



35,949



---

|16) | Total percentage holding of issued class following this notification
|--- | --------------------------------------------------------------------



0.09%



If a director has been granted options by the company please complete the following boxes



|17) | Date of grant
|--- | -------------



|18) | Period during which or date on which exercisable
|--- | ------------------------------------------------



|19) | Total amount paid (if any) for grant of the option
|--- | --------------------------------------------------



|20) | Description of shares or debentures involved: class, number
|--- | -----------------------------------------------------------



|21) | Exercise price (if fixed at time of grant) or indication that price is to be fixed at time of exercise
|--- | ------------------------------------------------------------------------------------------------------



|22) | Total number of shares or debentures over which options held following this notification
|--- | ----------------------------------------------------------------------------------------



|23) | Any additional information 24) Name of contact and telephone number for queries
|--- | -------------------------------------------------------------------------------



Diane Mellett, 01223 471471



|25) | Name and signature of authorised company official responsible for making this notification
|--- | ------------------------------------------------------------------------------------------



Diane Mellett, Company Secretary



Date of Notification 24 November 2003