Federal Register / Vol. 70, No. 198 / Friday, October 14, 2005 / Notices 60077 

biological processes associated with the 

absorption, distribution, metabolism, 

and elimination of compounds. With 

the appropriate data, these models can 

be used to extrapolate across species 

and exposure scenarios, and address 

various sources of uncertainty in risk 

assessments. This report addresses the 

following questions: (1) Why do risk 

assessors need PBPK models; (2) How 

can these models be used in risk 

assessments; and (3) What are the 

characteristics of acceptable PBPK 

models for use in risk assessment? 

Dated: October 6, 2005. 

Peter Preuss, 

Director, National Center for Environmental 

Assessment. 

[FR Doc. 05–20600 Filed 10–13–05; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–7983–5] 

Science Advisory Board Staff Office; 

Notification of Advisory Meeting of the 

SAB All-Ages Lead Model (AALM) 

Review Panel 

AGENCY: Environmental Protection 

Agency (EPA). 

ACTION: Notice. 

SUMMARY: The Environmental Protection 

Agency (EPA or Agency) Science 

Advisory Board (SAB) Staff Office 

announces a public meeting of the SAB 

All-Ages Lead Model Review Panel 

(Panel) for the purpose of providing the 

Agency with advice and 

recommendations on the recentlydeveloped All-Ages Lead Model. 

DATES: The meeting will be held 

Thursday, October 27, 2005, from 9 a.m. 

to 5:30 p.m. (eastern time), and Friday, 

October 28, 2005, from 9 a.m. to 2 p.m. 

(eastern time). 

ADDRESSES: The meeting will take place 

at SAB Conference Center, 1025 F 

Street, NW., Suite 3700, Washington, 

DC 20004. 

FOR FURTHER INFORMATION CONTACT: Any 

member of the public who would like to 

submit written or brief oral comments (5 

minutes or less), or wants further 

information concerning this meeting, 

may contact Mr. Fred Butterfield, 

Designated Federal Officer (DFO), EPA 

Science Advisory Board (1400F), U.S. 

Environmental Protection Agency, 1200 

Pennsylvania Avenue, NW., 

Washington, DC 20460; via telephone/ 

voice mail: (202) 343–9994; fax: (202) 

233–0643; or e-mail at: 

butterfield.fred@epa.gov. General 

information concerning the EPA Science 

Advisory Board can be found on the 

EPA Web site at: http://www.epa.gov/ 

sab. 

SUPPLEMENTARY INFORMATION: SAB and 

the AALM Review Panel: The SAB was 

established by 42 U.S.C. 4365 to provide 

independent scientific and technical 

advice, consultation, and 

recommendations to the EPA 

Administrator on the technical basis for 

Agency positions and regulations. The 

SAB is a Federal advisory committee 

chartered under the Federal Advisory 

Committee Act (FACA), as amended, 5 

U.S.C., App. The Panel will provide 

advice through the chartered SAB, and 

will comply with the provisions of 

FACA and all appropriate SAB Staff 

Office procedural policies. 

The SAB Staff Office recently 

established the SAB AALM Review 

Panel to provide the EPA Administrator, 

through the SAB, with advice and 

recommendations on the Agency’s AllAges Lead Model. The Panel will 

comply with the provisions of FACA 

and all appropriate SAB Staff Office 

procedural policies. 

Background: The SAB Staff Office has 

formed this Panel at the request of 

EPA’s Office of Research and 

Development (ORD), National Center for 

Environmental Assessment (NCEA), to 

provide advice and recommendations to 

the Agency on EPA’s recentlydeveloped All-Ages Lead Model 

(AALM). The AALM is designed to 

predict lead concentrations in body 

tissues and organs for a hypothetical 

individual, based on a simulated 

lifetime of lead exposure. Statistical 

methods can be used to extrapolate to a 

population of similarly-exposed 

individuals. The precursor to the AALM 

was the Integrated Exposure Uptake 

Biokinetic (IEUBK) Model for Lead in 

Children. The IEUBK Model underwent 

peer review by the SAB in 1991 and was 

subsequently revised in response to that 

review, leading to release of Version 

0.99d of the IEUBK Model in March 

1994. Since then, the IEUBK Model has 

been widely accepted and used in the 

risk assessment community as a tool for 

implementing the site-specific risk 

assessment process when the issue is 

childhood lead exposure. Based on 

further refinement of the IEUBK Model 

and its expansion for use with 

additional age groups beyond pediatric 

populations 6 years old or younger, the 

AALM has recently been developed to 

cover older childhood and adult lead 

exposure. The anticipated outcome will 

be reduced uncertainty in lead exposure 

assessments for children and adults. 

Any questions concerning either the 

AALM or the IEUBK Model for Lead in 

Children should be directed to Dr. 

Robert Elias, NCEA–RTP, at phone (919) 

541–4167; or e-mail 

elias.robert@epa.gov. 

Availability of Meeting Materials: 

NCEA–RTP has posted the ‘‘All-Ages 

Lead Model (AALM) Version 1.05 

(External Review Draft)’’ and related 

materials (including the Guidance 

Manual for the AALM Version 1.05) on 

the NCEA Web site at http:// 

cfpub.epa.gov/ncea/cfm/ 

recordisplay.cfm?deid=139314. 

Furthermore, the SAB Staff Office will 

post a copy of the final agenda and 

charge to the Panel for this advisory 

meeting on the SAB Web site at 

http://www.epa.gov/sab (under 

‘‘Meeting Agendas’’) and http:// 

www.epa.gov/sab/panels/ 

ad_hoc_aalm_rev_panel.htm in advance 

of the Panel meeting. 

Procedures for Providing Public 

Comment: The SAB Staff Office accepts 

written public comments of any length, 

and will accommodate oral public 

comments whenever possible. The SAB 

Staff Office expects that public will not 

repeat previously-submitted oral or 

written statements. Oral Comments: 

Requests to provide oral comments must 

be in writing (e-mail, fax or mail) and 

received by Mr. Butterfield no later than 

October 20, 2005 to reserve time on the 

October 27, 2005 meeting agenda. 

Opportunities for oral comments will be 

limited to five minutes per speaker. 

Written Comments: Written comments 

should be received in the SAB Staff 

Office by October 21, 2005 so that the 

comments may be made available to the 

members of the members of the SAB 

AALM Review Panel for their 

consideration. Comments should be 

supplied to Mr. Butterfield at the 

contact information provided above, in 

the following formats: one hard copy 

with original signature, and one 

electronic copy via e-mail (acceptable 

file format: Adobe Acrobat PDF, 

WordPerfect, Word, or Rich Text files 

(in IBM–PC/Windows 98/2000/XP 

format)). Those providing written 

comments and who attend the meeting 

in person are also asked to bring 75 

copies of their comments for public 

distribution. 

Meeting: Individuals requiring special 

accommodation at this meeting, 

including wheelchair access to the 

conference room, should contact Mr. 

Butterfield at the phone number or email address noted above no later than 

October 20, 2005 so that appropriate 

arrangements can be made. 

60078 Federal Register / Vol. 70, No. 198 / Friday, October 14, 2005 / Notices 

Dated: October 6, 2005. 

Anthony F. Maciorowski, 

Associate Director for Science, EPA Science 

Advisory Board Staff Office. 

[FR Doc. 05–20601 Filed 10–13–05; 8:45 am] 

BILLING CODE 6560–50–P 

ENVIRONMENTAL PROTECTION 

AGENCY 

[FRL–OW–FRL–7983–6] 

Notice of Data Availability and Request 

for Data and Information to Develop 

Ambient Water Quality Criteria for 

Protection of Human Health for 

Atrazine and Alachlor 

AGENCY: Environmental Protection 

Agency. 

ACTION: Notice of data availability; 

request for scientific data and 

information. 

SUMMARY: Section 304(a) of the Clean 

Water Act (CWA) requires the U.S. 

Environmental Protection Agency (EPA) 

to develop and publish, and from time 

to time revise, criteria for water 

accurately reflecting the latest scientific 

knowledge. Today, EPA is informing the 

public of data currently available to EPA 

and requesting data and information to 

develop Ambient Water Quality Criteria 

for Protection of Human Health for 

Atrazine and Alachlor. Lists of 

references available to the Agency for 

atrazine and alachlor will be posted on 

EPA’s Office of Science and 

Technology’s Home-page located at 

http://www.epa.gov/ost. In addition to 

seeking input on the references known 

to the Agency, EPA is also soliciting any 

additional pertinent data or information 

that may be useful in developing these 

criteria. 

DATES: Submit data and information on 

or before November 14, 2005. 

ADDRESSES: Data and information may 

be submitted electronically, by mail, or 

through hand deliver/courier. Follow 

the detailed instructions as provided in 

Unit B of the SUPPLEMENTARY

INFORMATION section. 

FOR FURTHER INFORMATION CONTACT: Dr. 

Amal Mahfouz, U.S. Environmental 

Protection Agency, Office of Water, 

Health and Ecological Criteria Division 

(4304T), 1200 Pennsylvania Avenue, 

NW., Washington, DC 20460; (202) 566–

1114; Mahfouz.amal@epa.gov (Data on 

toxicity of atrazine and alachlor) or Dr. 

Tala Henry, U.S. Environmental 

Protection Agency, Office of Water, 

Health and Ecological Criteria Division 

(4304T), 1200 Pennsylvania Avenue, 

NW., Washington, DC 20460; (202) 566–

1323; henry.tala@epa.gov (Data 

pertaining to bioaccumulation of 

atrazine and alachlor). 

SUPPLEMENTARY INFORMATION: 

I. General Information 

A. How Can I Get Copies of Related 

Information? 

1. Docket. EPA has established an 

official public docket for this Notice 

under Docket ID Nos. OW–2005–0008 

for Atrazine and OW–2005–0009 for 

Alachlor. The official public docket is 

the collection of materials that is 

available for public viewing at the Water 

Docket in the EPA Docket Center, EPA 

West, Room B102, 1301 Constitution 

Ave., NW., Washington, DC. Although a 

part of official docket, public docket 

does not include Confidential Business 

Information (CBI) or other information 

whose disclosure is restricted by statute. 

The EPA Docket Center Public Reading 

Room is open from 8:30 a.m. to 4:30 

p.m., Monday through Friday, excluding 

legal holidays. The telephone number 

for the Public Reading Room is (202) 

566–1744, and the telephone number for 

the Water Docket is (202) 566–2426. 

2. Electronic Access. You may access 

this Federal Register document 

electronically through the EPA Internet 

under the ‘‘Federal Register’’ listings at 

http://www.epa.gov/fedrgstr/. 

An electronic version of the public 

docket is available through EPA’s 

electronic public docket and comment 

system, EPA Dockets. You may use EPA 

Dockets at http://www.epa.gov/edocket/ 

to access the index listing of the 

contents of the official public docket 

and to access those documents in the 

public docket that are available 

electronically. Although not all docket 

materials may be available 

electronically, you may still access any 

of the publicly available docket 

materials through the docket facility 

identified in Section B.1. Once in the 

system, select ‘‘search,’’ then key in the 

appropriate docket identification 

number. 

B. How and to Whom Do I Submit Data 

and Information? 

You may submit data electronically, 

by mail, or through hand delivery/ 

courier. To ensure proper receipt by 

EPA, identify the appropriate docket 

identification number in the subject line 

on the first page. Please ensure that your 

data are submitted within the specified 

period. 

1. Electronically. If you submit data as 

prescribed below, EPA recommends that 

you include your name, mailing 

address, and an e-mail address or other 

contact information. Also include this 

contact information on the outside of 

any disk or CD ROM you submit, and 

in any cover letter accompanying the 

disk or CD ROM. This ensures that you 

can be identified as the submitter of the 

data and allows EPA to contact you in 

case EPA cannot read your data due to 

technical difficulties or needs further 

information on the substance of your 

data. EPA’s policy is that EPA will not 

edit your data, and any identifying or 

contact information provided in the 

body of the data will be included as part 

of the data that is placed in the official 

public docket, and made available in 

EPA’s electronic public docket. If EPA 

cannot read your data due to technical 

difficulties and cannot contact you for 

clarification, EPA may not be able to 

consider your comment. 

i. EPA Dockets. Your use of EPA’s 

electronic public docket to submit data 

to EPA electronically is EPA’s preferred 

method for receiving data. Go directly to 

EPA Dockets at http://www.epa.gov/ 

edocket, and follow the online 

instructions. Once in the system, select 

‘‘search,’’ and then key in Docket ID 

Nos. OW–2005–0008 for Atrazine or 

OW–2005–0009 for Alachlor. The 

system is an ‘‘anonymous access’’

system, which means EPA will not 

know your identity, e-mail address, or 

other contact information unless you 

provide it along with your data. 

ii. E-mail. Data may be sent by 

electronic mail (e-mail) to owdocket@epa.gov, Attention Docket ID 

Nos. OW–2005–0008 for Atrazine and 

OW–2005–0009 for Alachlor. In contrast 

to EPA’s electronic public docket, EPA’s 

e-mail system is not an ‘‘anonymous 

access’’ system. If you send an e-mail 

directly to the Docket without going 

through EPA’s electronic public docket, 

EPA’s e-mail system automatically 

captures your e-mail address. E-mail 

addresses that are automatically 

captured by EPA’s e-mail system are 

included as part of the comment that is 

placed in the official public docket, and 

made available in EPA’s electronic 

public docket. 

iii. Disk or CD ROM. You may submit 

data on a disk or CD ROM that you mail 

to the mailing address identified in Unit 

B.2. These electronic submissions will 

be accepted in WordPerfect or ASCII file 

format. Avoid the use of special 

characters and any form of encryption. 

2. By Mail. Send an original and three 

copies of any data or information to: 

Water Docket, Environmental Protection 

Agency, Mailcode: 4101T, 1200 

Pennsylvania Ave., NW., Washington, 

DC, 20460, Attention Docket ID Nos. 

OW–2005–0008 for Atrazine and OW–

2005–0009 for Alachlor. 

3. By Hand Delivery or Courier. 

Deliver your comments to: EPA Docket