EXECUTION
COPY




Exhibit
4.12














CENVEO
CORPORATION


(as
successor to Cadmus Communications Corporation)





the
SUBSIDIARY GUARANTORS named in Schedule I hereto





and





U.S. BANK
NATIONAL ASSOCIATION,


as
Trustee







SIXTH
SUPPLEMENTAL INDENTURE


Supplementing
the Indenture of
 June 15,
2004





Dated as
of November 7, 2007





83⁄8%
SENIOR SUBORDINATED NOTES DUE 2014

















THIS
SIXTH SUPPLEMENTAL INDENTURE, dated as of November 7, 2007 (this “Supplemental Indenture”), is
among Cenveo Corporation, a Delaware corporation (as successor to Cadmus
Communications Corporation, a Virginia corporation) (the “Company”), the Subsidiary
Guarantors (as defined herein) listed on Schedule I hereto (each a “Subsidiary Guarantor” and
collectively the “Subsidiary
Guarantors”), and U.S. Bank National Association (successor trustee to
Wachovia Bank, National Association), as trustee (the “Trustee”).





WHEREAS,
in connection with the issuance by the Company of its 83⁄8% Senior Subordinated
Notes due 2014 (the “Notes”), in the aggregate
principal amount of $125,000,000, the Company, certain Subsidiary Guarantors and
the Trustee entered into an indenture dated as of June 15, 2004 (as supplemented
by the First Supplemental Indenture dated as of March 1, 2005, the Second
Supplemental Indenture dated as of May 19, 2006, the Third Supplemental
Indenture and Amendment to Subsidiary Guarantee dated as of March 7, 2007, the
Fourth Supplemental Indenture dated as of July 9, 2007, and the Fifth
Supplemental Indenture dated as of August 30, 2007,  the “Indenture”; capitalized terms
used and not otherwise defined herein shall have the meaning set forth in the
Indenture); and





WHEREAS,
Section 9.01(4) of the Indenture provides that the Company, the Subsidiary
Guarantors and the Trustee may amend or supplement the Indenture and the Notes
without the consent of any holder of any outstanding Notes to make any change
that would provide any additional benefit or rights to such holders or that does
not adversely affect the legal rights thereunder of any such holder;
and





WHEREAS,
Cenveo Alberta Finance Limited Partnership, an Alberta limited partnership and a
wholly owned subsidiary of the Company, Cenveo McLaren Morris and Todd Company,
a Nova Scotia unlimited liability company and a wholly owned subsidiary of the
Company, and Cenveo MM&T Packaging Company, a Nova Scotia unlimited
liability company and a wholly owned subsidiary of the Company, desire to
Guarantee the payment of the Notes by becoming Subsidiary Guarantors;
and





WHEREAS,
the Company and each Subsidiary Guarantor has authorized the execution and
delivery of this Supplemental Indenture, as applicable; and





WHEREAS,
all things necessary to make this Supplemental Indenture a valid agreement of
the Company, the Subsidiary Guarantors and the Trustee have been
done.





NOW
THEREFORE, WITNESSETH, that, for and in consideration of the premises, and in
order to comply with the terms of Article Nine of the Indenture, the Company
agrees with the Subsidiary Guarantors and the Trustee as follows:










ARTICLE
1.


JOINDER
AND ASSUMPTION TO THE INDENTURE




SECTION
1.01.  AMENDMENT OF DEFINITION OF “SUBSIDIARY
GUARANTORS”


Effective as of the Operative Date (as
hereinafter defined), in accordance with the terms of the Indenture, clause (1)
of  the definition of “Subsidiary Guarantors” contained in Section
1.01 of the Indenture is hereby amended and restated in its entirety to read as
follows:





“(1) each
of Cadmus International Holdings, Inc., Cadmus Journal Services, Inc., Cadmus
Marketing Group, Inc., Cadmus Printing Group, Inc., Mack Printing Company, Port
City Press, Inc., Science Craftsman Incorporated, Washburn Graphics, Inc.,
Cadmus Investments, LLC, CDMS Management, LLC, Cenveo, Inc., CNMW Investments,
Inc., Cenveo Alberta Finance Limited Partnership, Cenveo McLaren Morris and Todd
Company and Cenveo MM&T Packaging Company;”





In
furtherance of the foregoing, each of Cenveo Alberta Finance Limited
Partnership, Cenveo McLaren Morris and Todd Company and Cenveo MM&T
Packaging Company hereby assumes and agrees to perform all obligations and
covenants of a Subsidiary Guarantor under the Indenture, and agrees that it
hereby shall become a Subsidiary Guarantor under and for all purposes of the
Indenture with all the rights and obligations of a Subsidiary Guarantor
thereunder.





The
obligations of Cenveo Alberta Finance Limited Partnership, Cenveo McLaren Morris
and Todd Company and Cenveo MM&T Packaging Company to the Holders of the
Notes and to the Trustee pursuant to the Note Guarantee are expressly
subordinated to the extent set forth in Article 10 of the Indenture and
reference is hereby made to the Indenture for the precise terms of such
subordination.





ARTICLE
2.


MISCELLANEOUS





SECTION
2.01.  OPERATIVE DATE


This
Supplemental Indenture is effective when executed (the “Operative Date”).




SECTION
2.02.  COUNTERPART ORIGINALS


The
parties may sign any number of copies of this Supplemental
Indenture.  Each signed copy shall be an original, but all of them
together shall constitute the same agreement.





2


SECTION
2.03.  GOVERNING LAW





This
Supplemental Indenture shall be governed by and construed in accordance with the
laws of the State of New York, without regard to its conflicts of laws
principles.




SECTION
2.04.  TRUSTEE’S DISCLAIMER


The
recitals contained herein shall be taken as the statements of the Company, and
the Trustee assumes no responsibility for their correctness.  The
Trustee makes no representation as to the validity or sufficiency of this
Supplemental Indenture.











3


IN
WITNESS WHEREOF, the parties hereto have caused this Supplemental Indenture to
be duly executed, all as of the date and year first written above.





CENVEO
      CORPORATIONBy:
            /s/ Mark S.
      HiltweinName:
            Mark
      S. HiltweinTitle:
            Chief
      Financial OfficerEACH
      ENTITY LISTED ON SCHEDULE I HERETOBy:
            /s/ Mark S.
      HiltweinName:
            Mark
      S. HiltweinTitle:
            Chief
      Financial OfficerU.S.
      BANK NATIONAL ASSOCIATION(successor
      trustee to Wachovia Bank, National
              Association),
      as TrusteeBy:
            /s/ Susan
    FreedmanName:
            Susan
      FreedmanTitle:
            Vice
      President


4


SCHEDULE
I





SCHEDULE OF SUBSIDIARY
GUARANTORS





DISCOUNT
LABELS, LLC


CENVEO
GOVERNMENT PRINTING, INC.


CENVEO
SERVICES, LLC


CENVEO
COMMERCIAL OHIO, LLC


CENVEO
RESALE OHIO, LLC


CENVEO
OMEMEE LLC


COLORHOUSE
CHINA, INC.


MMTP
HOLDINGS, INC.


CRX JV,
LLC


CRX
HOLDING, INC.


RX
TECHNOLOGY CORP.


RX
      JV HOLDING, INC.


PC
      INK CORP.


PRINTEGRA
      CORPORATION


CADMUS
      PRINTING GROUP, INC.


WASHBURN
      GRAPHICS, INC.


CADMUS
      JOURNAL SERVICES, INC.


CADMUS
      FINANCIAL DISTRIBUTION, INC.


CADMUS
      TECHNOLOGY SOLUTIONS, INC.


GARAMOND/PRIDEMARK
      PRESS, INC.


CADMUS
      DELAWARE, INC.


CADMUS
      UK, INC.


EXPERT
      GRAPHICS, INC.


CADMUS
      GOVERNMENT PUBLICATION SERVICES,
INC.


CADMUS
      MARKETING GROUP, INC.


AMERICAN
      GRAPHICS, INC.


CADMUS
      DIRECT MARKETING, INC.


CADMUS
      INTERACTIVE, INC.


CADMUS
      MARKETING, INC.


CADMUS/O’KEEFE
      MARKETING, INC.


OLD
      TSI, INC.


CADMUS
      INVESTMENTS, LLC


PORT
      CITY PRESS, INC.


SCIENCE
      CRAFTSMAN INCORPORATED


CADMUS
      INTERNATIONAL HOLDINGS, INC.


CDMS
      MANAGEMENT, LLC,


VAUGHAN
      PRINTERS INC.


VSUB
HOLDING COMPANY


MADISON/GRAHAM
COLORGRAPHICS, INC.


MADISON/GRAHAM
COLORGRAPHICS INTERSTATE SERVICES, INC.


COMMERCIAL
ENVELOPE MANUFACTURING CO., INC.


BERLIN &
JONES CO., LLC





HEINRICH
ENVELOPE, LLC


CENVEO
CEM, INC.


CENVEO
CEM, LLC


CENVEO,
INC.


CNMW
INVESTMENTS, INC.


CENVEO
ALBERTA FINANCE LIMITED PARTNERSHIP


CENVEO
MCLAREN MORRIS AND TODD COMPANY


CENVEO
MM&T PACKAGING COMPANY