EX-10.1



 Exhibit 10.1 

FOURTH AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT 

THIS FOURTH AMENDMENT TO AMENDED AND RESTATED CREDIT AGREEMENT (“Amendment”) is entered into as of April 2, 2014, by and
among CryoLife, Inc., a Florida corporation (“CryoLife”), AuraZyme Pharmaceuticals, Inc., a Florida corporation (“AuraZyme”), CryoLife International, Inc., a Florida corporation (“International”),
Cardiogenesis Corporation, a Florida corporation (“Cardiogenesis”) (CryoLife, AuraZyme, International and Cardiogenesis are sometimes referred to herein together as the “Borrowers” and individually as a
“Borrower”), CryoLife, as Borrower Representative, the other Credit Parties party hereto, General Electric Capital Corporation, a Delaware corporation (the “Agent”), as administrative agent for the lenders from time
to time party to the Credit Agreement described below (collectively, the “Lenders” and individually each a “Lender”) and for itself as a Lender and L/C Issuer, and such Lenders. 

RECITALS 
 A. The
Borrowers, the other Credit Parties signatory thereto, the Lenders signatory thereto from time to time and Agent are parties to that certain Amended and Restated Credit Agreement, dated as of October 28, 2011, as amended by that certain First
Amendment to Amended and Restated Credit Agreement, dated as of August 20, 2012, as further amended by that certain Second Amendment to Amended and Restated Credit Agreement, dated as of May 23, 2013, and as further amended by that certain
Third Amendment to Amended and Restated Credit Agreement, dated as of September 20, 2013 (as so amended and as may be further amended, supplemented, revised, restated, replaced or otherwise modified, the “Credit Agreement”).
Capitalized terms used in this Amendment without definition shall have the meanings ascribed to such terms in the Credit Agreement, as applicable. 

B. The Borrowers have requested that Lenders amend the Credit Agreement in certain respects and Lenders have agreed to so amend the Credit
Agreement, subject to the terms and conditions hereof. 
 NOW, THEREFORE, in consideration of the premises and the mutual covenants
hereinafter contained, and intending to be legally bound, the parties hereto agree as follows: 
 A. AMENDMENTS 

1. Amendment to Section 5.11. Section 5.11 of the Credit Agreement is hereby amended by replacing subsection (d) of such
Section in its entirety with the following: 
 (d) CryoLife may undertake purchases or redemptions of the common stock of
CryoLife pursuant to a stock buyback program (each, a “Stock Buyback”) in an aggregate amount not to exceed (i) $6,300,000 during the period commencing on the Initial Closing Date and ending on April 2, 2014 and
(ii) $14,000,000 during the period commencing on April 2, 2014 and ending on the Revolving Termination Date; provided, that (i) both before and after giving pro forma effect to each such Stock Buyback, the Credit Parties
shall be in compliance with the covenants set forth in Article VI as of the most recently 







 ended fiscal quarter for which financial statements have been delivered under
Section 4.1(a) or (b), (ii) both before and after giving pro forma effect to each such Stock Buyback, no Default or Event of Default shall have occurred and be continuing, (iii) after giving effect to each such Stock
Buyback the Credit Parties shall have at least $20,000,000 of Liquidity and (iv) the Credit Parties shall promptly comply with the requirements of Section 5.3 of the Guaranty and Security Agreement with respect to any Stock acquired
pursuant to a Stock Buyback which are not cancelled or retired and which remain issued and outstanding; and 
 B. CONDITIONS TO
EFFECTIVENESS  
 Notwithstanding any other provision of this Amendment and without affecting in any manner the rights of the Lenders
hereunder, it is understood and agreed that this Amendment shall not become effective, and the Borrower shall have no rights under this Amendment, until Agent shall have received duly executed signature pages to this Amendment from the Lenders,
Borrowers, L/C Issuer, Agent and each Credit Party. 
 C. REPRESENTATIONS 

Each Credit Party hereby represents and warrants to Lenders, L/C Issuer and Agent that: 

1. The execution, delivery and performance by such Credit Party of this Amendment (a) are within such Credit Party’s power;
(b) have been duly authorized by all necessary corporate, limited liability company or limited partnership action; (c) are not in contravention of any provision of such Credit Party’s certificate of incorporation or bylaws or other
organizational documents; (d) do not violate any law or regulation, or any order or decree of any Governmental Authority; (e) do not conflict with or result in the breach or termination of, constitute a default under or accelerate any
performance required by, any indenture, mortgage, deed of trust, lease, agreement or other instrument to which such Credit Party or any of its Subsidiaries is a party or by which such Credit Party or any such Subsidiary or any of their respective
property is bound; (f) do not result in the creation or imposition of any Lien upon any of the property of such Credit Party or any of its Subsidiaries other than those in favor of Agent, on behalf of itself and the Lenders, pursuant to the
Loan Documents; and (g) do not require the consent or approval of any Governmental Authority or any other Person. 
 2. This Amendment
has been duly executed and delivered for the benefit of or on behalf of each Credit Party and constitutes a legal, valid and binding obligation of each Credit Party, enforceable against such Credit Party in accordance with its terms except as the
enforceability hereof may be limited by bankruptcy, insolvency, reorganization, moratorium and other laws affecting creditors’ rights and remedies in general. 

3. Except as disclosed in writing to the Agent on the date hereof, both before and after giving effect to this Amendment, the representations
and warranties contained in the Credit Agreement and the other Loan Documents are true and correct in all material respects and no Default or Event of Default has occurred and is continuing as of the date hereof. 

  
 2 








 D. OTHER AGREEMENTS 

1. Continuing Effectiveness of Loan Documents. As amended hereby, all terms of the Credit Agreement and the other Loan Documents shall
be and remain in full force and effect and shall constitute the legal, valid, binding and enforceable obligations of the Credit Parties party thereto. To the extent any terms and conditions in any of the other Loan Documents shall contradict or be
in conflict with any terms or conditions of the Credit Agreement, after giving effect to this Amendment, such terms and conditions are hereby deemed modified and amended accordingly to reflect the terms and conditions of the Credit Agreement as
modified and amended hereby. Upon the effectiveness of this Amendment such terms and conditions are hereby deemed modified and amended accordingly to reflect the terms and conditions of the Credit Agreement as modified and amended hereby. 

2. Reaffirmation of Loan Documents. Each Credit Party consents to the execution and delivery of this Amendment by all parties hereto
and the consummation of the transactions described herein, and ratifies and confirms the terms of the Credit Agreement, that certain Guaranty and Security Agreement, dated as of March 27, 2008 and reaffirmed by that certain Omnibus
Reaffirmation Agreement, dated as of October 28, 2011 (as amended, supplemented, modified, the “Guaranty and Security Agreement”) and each other Loan Document to which such Credit Party is a party with respect to the
indebtedness now or hereafter outstanding under the Credit Agreement as amended hereby and all promissory notes issued thereunder. Each Credit Party acknowledges that, notwithstanding anything to the contrary contained herein or in any other
document evidencing any indebtedness of any Borrower to the Lenders or any other obligation of Borrowers, or any actions now or hereafter taken by the Lenders with respect to any obligation of Borrowers, the Guaranty and Security Agreement
(i) is and shall continue to be a primary obligation of such Credit Party, (ii) is and shall continue to be an absolute, unconditional, continuing and irrevocable guaranty of payment, and (iii) is and shall continue to be in full
force and effect in accordance with its terms. Nothing contained herein to the contrary shall release, discharge, modify, change or affect the original liability of any Credit Party under the Guaranty and Security Agreement. 

3. Acknowledgment of Perfection of Security Interest. Each Credit Party hereby acknowledges that, as of the date hereof, the security
interests and liens granted to Agent, the L/C Issuer and the Lenders under the Credit Agreement and the other Loan Documents are in full force and effect, are properly perfected and are enforceable in accordance with the terms of the Credit
Agreement and the other Loan Documents. 
 4. Effect of Agreement. Except as set forth expressly herein, all terms of the Credit
Agreement, as amended hereby, and the other Loan Documents shall be and remain in full force and effect and shall constitute the legal, valid, binding and enforceable obligations of the Borrowers to the Lenders, the L/C Issuer and Agent. The
execution, delivery and effectiveness of this Amendment shall not, except as expressly provided herein, operate as a waiver of any right, power or remedy of the Lenders under the Credit Agreement, nor constitute a waiver of any provision of the
Credit Agreement. This Amendment shall constitute a Loan Document for all purposes of the Credit Agreement. 

  
 3 








 5. Governing Law. This Amendment shall be governed by, and construed in accordance
with, the internal laws of the State of New York and all applicable federal laws of the United States of America. 
 6. No
Novation. This Amendment is not intended by the parties to be, and shall not be construed to be, a novation of the Credit Agreement and the other Loan Documents or an accord and satisfaction in regard thereto. 

7. Costs and Expenses. The Borrowers agree to pay on demand all costs and expenses of Agent in connection with the preparation,
execution and delivery of this Amendment, including, without limitation, the reasonable fees and out-of-pocket expenses of outside counsel for Agent with respect thereto. 

8. Counterparts. This Amendment may be executed by one or more of the parties hereto in any number of separate counterparts, each of
which shall be deemed an original and all of which, taken together, shall be deemed to constitute one and the same instrument. Delivery of an executed counterpart of this Amendment by facsimile transmission, Electronic Transmission or containing an
E-Signature shall be as effective as delivery of a manually executed counterpart hereof. 
 9. Binding Nature. This Amendment shall
be binding upon and inure to the benefit of the parties hereto, their respective successors, successors-in-titles, and assigns. 
 10.
Entire Understanding. This Amendment sets forth the entire understanding of the parties with respect to the matters set forth herein, and shall supersede any prior negotiations or agreements, whether written or oral, with respect thereto.

 [signature pages to follow] 

  
 4 








 IN WITNESS WHEREOF, this Amendment has been duly executed as of the date first written above.

  

					
	BORROWERS:
	
	CRYOLIFE, INC.
		
	By:	 	/s/ D. A. Lee
	Name:	 		 	D. Ashley Lee
	Title:	 		 	 Executive Vice President, Chief

    Financial Officer and Chief Operating

    Officer

	
	AURAZYME PHARMACEUTICALS, INC.
		
	By:	 	/s/ D. A. Lee
	Name:	 		 	D. Ashley Lee
	Title:	 		 	 Executive Vice President, Chief

    Financial Officer and Chief Operating

    Officer

	
	CRYOLIFE INTERNATIONAL, INC.
		
	By:	 	/s/ D. A. Lee
	Name:	 		 	D. Ashley Lee
	Title:	 		 	 Executive Vice President, Chief

    Financial Officer and Chief Operating

    Officer

	
	CARDIOGENESIS CORPORATION
		
	By:	 	/s/ D. A. Lee
	Name:	 		 	D. Ashley Lee
	Title:	 		 	 Executive Vice President, Chief

    Financial Officer and Chief Operating

    Officer

	
	HEMOSPHERE, INC.
		
	By:	 	/s/ D. A. Lee
	Name:	 		 	D. Ashley Lee
	Title:	 		 	 Executive Vice President, Chief

    Financial Officer and Chief Operating

    Officer



 [Signature Page to Fourth Amendment to Amended and Restated Credit Agreement] 

  
 5 








 
			
	AGENT, L/C ISSUER AND LENDERS:
	
	 GENERAL ELECTRIC CAPITAL

CORPORATION, as Agent, L/C Issuer and sole Lender

		
	By:	 	/s/ Andrew Moore
		 	Its Duly Authorized Signatory


 [Signature Page to Fourth Amendment to Amended and Restated Credit Agreement] 

  
 6