Second Supplemental Indenture



 Exhibit 4.7 

 
  

 
 HOLOGIC, INC. 

 
 ISSUER 

 
  

 
 WILMINGTON TRUST COMPANY 

 
 TRUSTEE 

 
  

 
 SECOND SUPPLEMENTAL INDENTURE 

 
 Dated as of November 23, 2010 

 
 To 
  
 INDENTURE 
  

Dated as of December 10, 2007 
  

 
  

2.00% CONVERTIBLE EXCHANGE SENIOR NOTES DUE 2037 
  

 







 HOLOGIC, INC. 

 
 Certain Sections of this Indenture relating to
Sections 310 through 318 
 of the Trust Indenture Act of 1939: 

 

			
	   Trust Indenture  

      Act Section
	  	 Supplemental
Indenture Section

		
	§ 310(a)(1)	  	Not Applicable
	         (a)(2)	  	Not Applicable
	         (a)(3)	  	Not Applicable
	         (a)(4)	  	Not Applicable
	         (b)	  	Not Applicable
		  	Not Applicable
	§ 311(a)	  	Not Applicable
	         (b)	  	Not Applicable
	§ 312(a)	  	9.01
		  	9.02(a)
	         (b)	  	9.02(b)
	         (c)	  	9.02(c)
	§ 313(a)	  	Not Applicable
	         (b)	  	Not Applicable
	         (c)	  	Not Applicable
	         (d)	  	Not Applicable
	§ 314(a)	  	10.06
	         (b)	  	Not Applicable
	         (c)(1)	  	Not Applicable
	         (c)(2)	  	Not Applicable
	         (c)(3)	  	Not Applicable
	         (d)	  	Not Applicable
	         (e)	  	Not Applicable
	§ 315(a)	  	Not Applicable
	         (b)	  	Not Applicable
	         (c)	  	Not Applicable
	         (d)	  	Not Applicable
	         (e)	  	5.15
	§ 316(a)(1)(A)	  	5.06
	         (a)(1)(B)	  	5.04
	         (a)(2)	  	Not Applicable
	         (b)	  	5.03
	         (c)	  	Not Applicable
	§ 317(a)(1)	  	5.07
	         (a)(2)	  	5.08
	         (b)	  	10.05
	§ 318(a)	  	Not Applicable

  

Note: This reconciliation and tie shall not, for any purpose, be deemed to be a part of this Indenture. 







 TABLE OF CONTENTS 
  

							
	 	 	 	  	PAGE	 
		 	ARTICLE 1	  			
		 	DEFINITIONS AND OTHER PROVISIONS OF GENERAL
APPLICATION	  			
			
	SECTION 1.01	 	Definitions	  	 	1	  
	SECTION 1.02	 	[Reserved.]	  	 	12	  
	SECTION 1.03	 	[Reserved.]	  	 	12	  
	SECTION 1.04	 	Effect of Headings and Table of Contents	  	 	12	  
	SECTION 1.05	 	[Reserved.]	  	 	12	  
	SECTION 1.06	 	[Reserved.]	  	 	12	  
	SECTION 1.07	 	[Reserved.]	  	 	12	  
	SECTION 1.08	 	Conflict With Trust Indenture Act	  	 	12	  
	SECTION 1.09	 	Successors and Assigns	  	 	12	  
	SECTION 1.10	 	Separability Clause	  	 	13	  
	SECTION 1.11	 	Benefits of Indenture	  	 	13	  
	SECTION 1.12	 	Governing Law	  	 	13	  
	SECTION 1.13	 	Legal Holidays	  	 	13	  
	SECTION 1.14	 	[Reserved.]	  	 	13	  
	SECTION 1.15	 	Relationship with Base Indenture	  	 	13	  
			
		 	ARTICLE 2	  			
		 	NOTE FORMS	  			
			
	SECTION 2.01	 	Form Generally	  	 	14	  
	SECTION 2.02	 	Form of Note	  	 	14	  
	SECTION 2.03	 	Form of Notice of Conversion	  	 	24	  
	SECTION 2.04	 	Form of Assignment	  	 	25	  
			
		 	ARTICLE 3	  			
		 	THE NOTES	  			
			
	SECTION 3.01	 	Title And Terms	  	 	26	  
	SECTION 3.02	 	Regular Interest	  	 	26	  
	SECTION 3.03	 	Contingent Interest	  	 	27	  
	SECTION 3.04	 	Accretion	  	 	27	  
	SECTION 3.05	 	Denominations	  	 	27	  
	SECTION 3.06	 	Execution, Authentication, Delivery and Dating	  	 	27	  
	SECTION 3.07	 	Global Notes; Non-Global Notes; Book-entry Provisions	  	 	28	  
	SECTION 3.08	 	Persons Deemed Owners	  	 	30	  
	SECTION 3.09	 	Mutilated, Destroyed, Lost and Stolen Notes	  	 	30	  
	SECTION 3.10	 	Payment of Interest; Interest Rights Preserved	  	 	31	  
	SECTION 3.11	 	Cancellation	  	 	32	  
	SECTION 3.12	 	Computation of Interest	  	 	32	  


  
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	 	 	ARTICLE 4	  	 	 
		 	DISCHARGE	  			
			
	SECTION 4.01	 	Discharge of Liability on Notes	  	 	32	  
	SECTION 4.02	 	Reinstatement	  	 	33	  
	SECTION 4.03	 	Officers’ Certificate; Opinion of Counsel	  	 	33	  
			
		 	ARTICLE 5	  			
		 	REMEDIES	  			
			
	SECTION 5.01	 	Events of Default	  	 	33	  
	SECTION 5.02	 	Acceleration of Maturity; Rescission and Annulment	  	 	35	  
	SECTION 5.03	 	Unconditional Right of Holders to Receive Principal and Interest and to Convert	  	 	36	  
	SECTION 5.04	 	Waiver of Past Defaults and Rescission of Acceleration	  	 	36	  
	SECTION 5.05	 	Waiver of Stay, Usury or Extension Laws	  	 	37	  
	SECTION 5.06	 	Control by Holders	  	 	37	  
	SECTION 5.07	 	Collection of Indebtedness and Suits for Enforcement by Trustee	  	 	37	  
	SECTION 5.08	 	Trustee May File Proofs of Claim	  	 	38	  
	SECTION 5.09	 	Trustee May Enforce Claims Without Possession of Notes	  	 	38	  
	SECTION 5.10	 	Application of Money Collected	  	 	39	  
	SECTION 5.11	 	Limitation on Suits	  	 	39	  
	SECTION 5.12	 	Restoration of Rights and Remedies	  	 	40	  
	SECTION 5.13	 	Rights and Remedies Cumulative	  	 	40	  
	SECTION 5.14	 	Delay or Omission Not Waiver	  	 	40	  
	SECTION 5.15	 	Undertaking for Costs	  	 	40	  
			
		 	ARTICLE 6	  			
		 	[RESERVED.]	  			
			
		 	ARTICLE 7	  			
		 	CONSOLIDATION, MERGER, CONVEYANCE, TRANSFER OR LEASE	  			
			
	SECTION 7.01	 	Company May Consolidate, Etc., Only on Certain Terms	  	 	41	  
	SECTION 7.02	 	Successor Substituted	  	 	41	  
			
		 	ARTICLE 8	  			
		 	SUPPLEMENTAL INDENTURES	  			
			
	SECTION 8.01	 	Supplemental Indentures Without Consent of Holders	  	 	41	  
	SECTION 8.02	 	Supplemental Indentures With Consent of Holders	  	 	42	  
	SECTION 8.03	 	Notice of Supplemental Indentures	  	 	43	  
	SECTION 8.04	 	Effect of Supplemental Indentures	  	 	44	  
	SECTION 8.05	 	Conformity with Trust Indenture Act	  	 	44	  


  
 ii 










							
	 	 	ARTICLE 9	  	 	 
		 	HOLDERS LISTS AND BY TRUSTEE AND COMPANY	  			
			
	SECTION 9.01	 	Company to Furnish Trustee Names and Addresses of Holders	  	 	44	  
	SECTION 9.02	 	Preservation of Information	  	 	44	  
			
		 	ARTICLE 10	  			
		 	COVENANTS	  			
			
	SECTION 10.01	 	Payment of Principal and Interest	  	 	45	  
	SECTION 10.02	 	Maintenance of Offices or Agencies	  	 	45	  
	SECTION 10.03	 	Existence	  	 	46	  
	SECTION 10.04	 	Annual Statement by Officers	  	 	46	  
	SECTION 10.05	 	Money for Note Payments to Be Held in Trust	  	 	46	  
	SECTION 10.06	 	Reports by Company	  	 	47	  
	SECTION 10.07	 	[Reserved]	  	 	47	  
	SECTION 10.08	 	Tax Treatment of Notes	  	 	47	  
			
		 	ARTICLE 11	  			
		 	REDEMPTION AND REPURCHASE OF NOTES	  			
			
	SECTION 11.01	 	Right to Redeem; Notice to Trustee	  	 	48	  
	SECTION 11.02	 	Selection of Notes to Be Redeemed	  	 	48	  
	SECTION 11.03	 	Notice of Redemption	  	 	49	  
	SECTION 11.04	 	Effect of Notice of Redemption	  	 	50	  
	SECTION 11.05	 	Deposit of Redemption Price	  	 	50	  
	SECTION 11.06	 	Notes Redeemed in Part	  	 	50	  
	SECTION 11.07	 	No Redemption of Notes Upon Occurrence of Acceleration	  	 	50	  
	SECTION 11.08	 	Repurchase of Notes at the Option of Holders	  	 	51	  
	SECTION 11.09	 	Right to Require Repurchase Upon a Fundamental Change	  	 	55	  
			
		 	ARTICLE 12	  			
		 	CONVERSION OF NOTES	  			
			
	SECTION 12.01	 	Conversion Privilege and Conversion Rate	  	 	59	  
	SECTION 12.02	 	Exercise of Conversion Privilege	  	 	63	  
	SECTION 12.03	 	Fractions of Shares	  	 	66	  
	SECTION 12.04	 	Adjustment of Conversion Rate	  	 	67	  
	SECTION 12.05	 	Notice of Adjustments of Conversion Rate	  	 	76	  
	SECTION 12.06	 	Company to Reserve Common Stock	  	 	76	  
	SECTION 12.07	 	Taxes on Conversions	  	 	76	  
	SECTION 12.08	 	Certain Covenants	  	 	77	  
	SECTION 12.09	 	Cancellation of Converted Notes	  	 	77	  
	SECTION 12.10	 	Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale	  	 	77	  
	SECTION 12.11	 	Company Responsible for Making Calculations	  	 	79	  
	SECTION 12.12	 	Responsibility of Trustee for Conversion Provisions	  	 	79	  


  
 iii









 SECOND SUPPLEMENTAL INDENTURE, dated as of November 23, 2010 (this
“Supplemental Indenture,” together with the Base Indenture (as defined below), the “Indenture”), between HOLOGIC, INC., a corporation duly organized and existing under the laws of the State of Delaware,
having its principal office at 35 Crosby Drive, Bedford, Massachusetts 01730 (herein called the “Company”), and WILMINGTON TRUST COMPANY, as Trustee hereunder (herein called the “Trustee”). 

 
 RECITALS OF THE COMPANY 

 
 The Company has heretofore executed and
delivered to the Trustee an Indenture, dated as of December 10, 2007 (the “Base Indenture”). 
  

The Company desires and has requested the Trustee pursuant to Section 9.1 of the Base Indenture to join with them in
the execution and delivery of this Supplemental Indenture in order to supplement the Base Indenture as and to the extent set forth herein to provide for the issuance and the terms of the Company’s 2.00% Convertible Exchange Senior Notes due
2037 (herein called the “Notes”). 
  
 Section 9.1 of the Base Indenture provides that a supplemental indenture may be entered into by the Company and the Trustee without the consent of any Holders to establish the form or terms of
Securities (as defined in the Base Indenture) of any series as permitted by Sections 2.1 and 3.1 of the Base Indenture. 
  

The execution and delivery of this Supplemental Indenture has been duly authorized by a Board Resolution of the Company,
and all things necessary to make the Notes, when the Notes are executed by the Company and authenticated and delivered hereunder, the valid obligations of the Company have been done. Further, all things necessary to duly authorize the issuance of
the Common Stock issuable upon the conversion of the Notes, and to duly reserve for issuance the number of shares of Common Stock (or, at the election of the Company, cash or a combination of cash and shares of Common Stock) issuable upon such
conversion, have been done. 
  
 NOW, THEREFORE,
THIS INDENTURE WITNESSETH: 
  

For and in consideration of the premises and the purchase of the Notes by the Holders thereof, it is mutually covenanted
and agreed, for the equal and proportionate benefit of all Holders of the Notes, as follows: 
  
 ARTICLE 1 
 DEFINITIONS AND OTHER
PROVISIONS OF GENERAL APPLICATION 
  
 SECTION 1.01 Definitions. 
  

For all purposes of this Supplemental Indenture, except as otherwise expressly provided or unless the context otherwise
requires: 
  
 (a) capitalized terms used but not
defined herein shall have the respective meanings assigned to them in the Trust Indenture Act or the Base Indenture; 

  
 1 








 (b) the terms defined in this Article 1 have the meanings assigned to them in this Article 1
and include the plural as well as the singular; 
  

(c) all accounting terms not otherwise defined herein have the meanings assigned to them in accordance with generally accepted accounting
principles in the United States, and, except as otherwise herein expressly provided, the term “generally accepted accounting principles” with respect to any computation required or permitted hereunder shall mean such accounting principles
as are generally accepted at the date of such computation; and 
  
 (d) all other terms used in this Supplemental Indenture, which are defined in the Trust Indenture Act or which are by reference therein defined in the Securities Act (except as herein otherwise expressly
provided or unless the context otherwise requires), shall have the meanings assigned to such terms in the Trust Indenture Act and in the Securities Act as in force at the date of the execution of this Indenture. The words “herein,”
“hereof” and “hereunder” and other words of similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. 

 
 “Accreted Principal Amount”
means the Original Principal Amount as adjusted upward for accretion as described in Section 3.04; provided that prior to December 15, 2016, references to the Accreted Principal Amount shall mean the Original Principal Amount.

  
 “Additional
Notes” means an unlimited amount of Notes (other than the Initial Notes) issued under this Indenture in accordance with Section 3.06, as part of the same series as the Initial Notes. 

 
 “Additional Shares” has the
meaning specified in Section 12.01(e). 
  
 “Adjustment Determination Date” has the meaning specified in Section 12.04(i). 
  

“Adjustment Event” has the meaning specified in Section 12.04(i). 

 
 “Agent Member” means any
member of, or participant in, the Depositary. 
  
 “American Depositary Receipt” means a negotiable United States security that represents a non-United States company’s publicly traded equity. 

 
 “Applicable Procedures”
means, with respect to any transfer or transaction involving a Global Note or beneficial interest therein, the rules and procedures of DTC or any successor Depositary, in each case to the extent applicable to such transaction and as in effect from
time to time. 
  
 “Base
Indenture” has the meaning ascribed to it in the first paragraph under the caption “Recitals of the Company.” 
  

“Board of Directors” means either the board of directors of the Company or any duly authorized committee
of that board. 

  
 2 








 “Board Resolution” means a copy of a resolution certified
by the Secretary or an Assistant Secretary of the Company to have been duly adopted by the Board of Directors and to be in full force and effect on the date of such certification, and delivered to the Trustee. 

 
 “Capital Stock” means, for
any entity, any and all shares, interests, rights to purchase, warrants, options, participations or other equivalents of or interests in (however designated) stock issued by that entity. 
  
 “Certificated Note” means a certificated Note registered in the name of the
Holder thereof and issued in accordance with this Supplemental Indenture, substantially in the form of Section 2.02 hereof, except that such Note will not bear the Global Note Legend. 
  
 “Code” means the Internal Revenue Code of 1986 as in effect on the date
hereof. 
  
 “Common
Stock” means the Common Stock, par value $0.01 per share, of the Company authorized at the date of this instrument as originally executed or as such stock may be constituted from time to time. Subject to the provisions of
Section 12.10, shares issuable upon conversion of Notes shall include only shares of Common Stock or shares of any class or classes of common stock resulting from any reclassification or reclassifications thereof; provided,
however, that if at any time there shall be more than one such resulting class, the shares so issuable on conversion of Notes shall include shares of all such classes, and the shares of each such class then so issuable shall be substantially in
the proportion which the total number of shares of such class resulting from all such reclassifications bears to the total number of shares of all such classes resulting from all such reclassifications. 

 
 “common stock” includes any
stock of any class of Capital Stock which has no preference in respect of dividends or of amounts payable in the event of any voluntary or involuntary liquidation, dissolution or winding up of the issuer thereof and which is not subject to
redemption by the issuer thereof. 
  

“Company” means the Person named as the “Company” in the first paragraph of this instrument
until a successor Person shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Company” shall mean such successor Person. 

 
 “Consideration Notice” has
the meaning specified in 12.02(b). 
  

“Contingent Interest” means interest that accrues and is payable as provided in Section 3.03.

  
 “Contingent Payment Debt
Regulations” has the meaning specified in Section 10.08. 
  
 “Conversion Agent” means any Person authorized by the Company to convert Notes in accordance with Article 12. The Company has initially appointed the Trustee as its Conversion Agent
pursuant to Section 10.02. 
  

“Conversion Consideration” has the meaning specified in Section 12.02(c). 

  
 3 








 “Conversion Date” has the meaning specified in
Section 12.02(d). 
  

“Conversion Obligation” means the obligation of the Company to deliver the consideration due under
Article 12 upon a conversion of the Notes in accordance herewith. 
  
 “Conversion Price” means at any given time the amount equal to $1,000 divided by the then current Conversion Rate. 

 
 “Conversion Rate” has the
meaning specified in Section 12.01(a). 
  
 “corporation” means a corporation, company, association, joint-stock company or business trust. 
  

“Custodian” means the Trustee, as custodian with respect to the Notes in global form, or any successor
entity thereto. 
  
 “Daily
Cash Amount” has the meaning specified in the definition of Daily Settlement Amount. 
  

“Daily Conversion Value” means, for each of the 30 consecutive VWAP Trading Days during the applicable
Observation Period, one-thirtieth (1/30) of the product of (a) the applicable Conversion Rate and (b) the Daily VWAP of the Common Stock (or the Reference Property pursuant to Section 12.10) on such VWAP Trading Day, as
determined by the Company. Any such determination shall be conclusive absent manifest error. 
  

“Daily Settlement Amount” means, for each of the 30 VWAP Trading Days during the Observation Period,

  
 (a) an amount of cash equal to
the lesser of (i) the quotient of the Specified Dollar Amount and 30 and (ii) the Daily Conversion Value relating to such VWAP Trading Day (the “Daily Cash Amount”); and 

 
 (b) if such Daily Conversion Value exceeds
the Daily Cash Amount, a number of shares (the “Deliverable Shares”) of Common Stock equal to (i) the difference between such Daily Conversion Value and the Daily Cash Amount divided by (ii) the Daily VWAP of the Common
Stock for such VWAP Trading Day. 
  

“Daily VWAP” of the Common Stock means, for any VWAP Trading Day, the per share volume-weighted average
price as displayed under the heading “Bloomberg VWAP” on Bloomberg page HOLX.Q <equity> AQR (or any equivalent successor page) in respect of the period from 9:30 a.m. to 4:00 p.m., New York City time, on such VWAP Trading Day, or if
such volume-weighted average price is unavailable, the market value of one share of Common Stock on such VWAP Trading Day using a volume-weighted method as determined by a nationally recognized independent investment banking firm retained for this
purpose by the Company. 
  

“Default” means any event which is, or after notice or lapse of time or both would become, an Event of
Default pursuant to Section 5.01. 

  
 4 








 “Defaulted Interest” has the meaning specified in
Section 3.10. 
  

“Deliverable Shares” has the meaning specified in the definition of Daily Settlement Amount. 

 
 “Delivery Date” has the
meaning specified in Section 12.04(l). 
  
 “Depositary” means, with respect to Notes issuable in whole or in part in the form of one or more Global Notes, a clearing agency registered under the Exchange Act that is designated to
act as Depositary for such Notes as contemplated by Section 3.07. 
  
 “Distributed Property” has the meaning specified in Section 12.04(c). 
  

“DTC” means The Depository Trust Company, a New York corporation, or any successor. 

 
 “Effective Date” means the
date on which a Fundamental Change occurs or becomes effective. 
  
 “Event of Default” has the meaning specified in Section 5.01. 
  

“Ex-Date” means, with respect to any distribution on the Common Stock, the first date on which the shares
of Common Stock trade on the relevant exchange or in the relevant market, regular way, without the right to receive the distribution in question. 
  

“Exchange Act” means the Securities Exchange Act of 1934 and any statute successor thereto, in each case
as amended from time to time. 
  

“Exchange Election” has the meaning specified in Section 12.02(c). 

 
 “Extension Fee” has the
meaning specified in Section 5.02. 
  
 “Extension Right” has the meaning specified in Section 5.02. 
  

“Financial Institution” has the meaning specified in Section 12.02(c). 

 
 “Fundamental Change” will
be deemed to have occurred at the time after the Issue Date that any of the following occurs: 
  

(1) any Person acquires beneficial ownership, directly or indirectly, through a purchase, merger or other acquisition
transaction or series of transactions, of shares of the Company’s Capital Stock entitling the Person to exercise 50% or more of the total voting power of all shares of the Company’s Capital Stock entitled to vote generally in elections of
directors, other than an acquisition by the Company, any of the Company’s Subsidiaries or any of the Company’s employee benefit plans (for purposes of this clause (1), whether a Person is a “beneficial owner” shall be determined
in accordance with Rule 13d-3 under the Exchange Act, and “Person” shall include any syndicate or group that would be deemed to be a “person” under Section 13(d)(3) of the Exchange Act); or 

  
 5 








 (2) the Company (i) merges or consolidates with or into any other
Person, another Person merges with or into the Company, or the Company conveys, sells, transfers or leases all or substantially all of the Company’s assets to another Person or (ii) engages in any recapitalization, reclassification or
other transaction in which all or substantially all of the Common Stock is exchanged for or converted into cash, securities or other property, in each case other than a merger or consolidation: 

 
 (a) that does not result in a
reclassification, conversion, exchange or cancellation of the Company’s outstanding Common Stock; or 
  

(b) which is effected solely to change the Company’s jurisdiction of incorporation and results in a
reclassification, conversion or exchange of outstanding shares of the Common Stock solely into shares of common stock of the surviving entity; 
  

(3) the Company is liquidated or dissolved or holders of Common Stock approve any plan or proposal for the Company’s
liquidation or dissolution; or 
  

(4) if shares of the Common Stock, or shares of any other Capital Stock or American Depository Receipts in respect of
shares of Capital Stock into which the Notes are convertible pursuant to the terms of this Supplemental Indenture, are not listed for trading on any of the New York Stock Exchange, the American Stock Exchange, the NASDAQ Global Market or the NASDAQ
Global Select Market (or any of their respective successors). 
  
 “Fundamental Change Repurchase Date” has the meaning specified in Section 11.09(a). 
  

“Fundamental Change Repurchase Notice” has the meaning specified in Section 11.09(a)(i). 

 
 “Fundamental Change Repurchase
Price” has the meaning specified in Section 11.09(a). 
  
 “Fundamental Change Repurchase Right Notice” has the meaning specified in Section 11.09(b). 
  

“Global Note” means a Note bearing the Global Note Legend that is registered in the Securities Register
in the name of a Depositary or a nominee thereof. 
  
 “Global Note Legend” means the legend set forth in Section 2.02, which is required to be placed on all Global Notes issued under this Supplemental Indenture. 

 
 “Holder” means the Person
in whose name the Note is registered in the Securities Register. 
  
 “Indenture” has the meaning specified in the first paragraph of this instrument. 

  
 6 








 “Initial Notes” means the first $450,000,000 aggregate
Original Principal Amount of the Notes issued under this Supplemental Indenture on the date hereof. The Initial Notes and the Additional Notes shall be treated as a single class for all purposes under this Supplemental Indenture, and unless the
context otherwise requires, all references to the Notes shall include the Initial Notes and any Additional Notes. 
  

“Interest” means Regular Interest and Contingent Interest, if any. 

 
 “Interest Payment Date”
means June 15 and December 15 of each year, beginning on December 15, 2010 and ending on December 15, 2016. 
  

“Interest Period” has the meaning specified in Section 3.02. 

 
 “Issue Date” means
November 23, 2010. 
  

“Last Reported Sale Price” means, with respect to the Common Stock, on any date, the closing sale price
per share (or if no closing sale price is reported, the average of the last bid and ask prices or, if more than one in either case, the average of the average last bid and the average last ask prices) on such date as reported in composite
transactions for the principal United States national or regional securities exchange on which the Common Stock is traded, as determined by the Company. If the Common Stock is not listed for trading on a United States national or regional securities
exchange on the relevant date, the “Last Reported Sale Price” shall be the average of the last quoted bid and ask prices per share of Common Stock in the over-the-counter market on the relevant date, as reported by the National Quotation
Bureau or similar organization. If the Common Stock is not so quoted, the Last Reported Sale Price shall be the average of the mid-point of the last bid and ask prices for the Common Stock on the relevant date from each of at least three nationally
recognized independent investment banking firms selected by the Company for that purpose. Any such determination shall be conclusive absent manifest error. The Last Reported Sale Price shall be determined without reference to extended or after hours
trading. 
  
 “Make-Whole
Fundamental Change” means any transaction or event that occurs prior to December 15, 2016 and that constitutes a Fundamental Change pursuant to clauses (1), (2) or (3) under the definition of Fundamental Change. 

 
 “Make-Whole Reference Date”
means with respect to any Make-Whole Fundamental Change, the date on which such Make-Whole Fundamental Change occurs or becomes effective; provided that for the purpose of determining the number of Additional Shares pursuant to
Section 12.01(e), the “Make-Whole Reference Date” with respect to any Make-Whole Fundamental Change that constitutes a Fundamental Change pursuant to clauses (1) or (2) under the definition of Fundamental Change shall be
deemed to be the earlier of (i) the date on which such Make-Whole Fundamental Change occurs or becomes effective or (ii) the date of the first public announcement of such Make-Whole Fundamental Change by the Company or any counterparty to
such Make-Whole Fundamental Change. 
  
 “Market Disruption Event” means the occurrence or existence on any Scheduled Trading Day for the Common Stock of any suspension or limitation imposed on trading (by


  
 7 








 
reason of movements in price exceeding limits permitted by the stock exchange or otherwise) in the Common Stock or in any options contracts or futures contracts relating to the Common Stock, and
such suspension or limitation occurs or exists at any time within the 30 minutes prior to the closing time of the relevant exchange on such day. 
  

“Maturity,” when used with respect to any Notes, means the date on which the principal of such Notes
becomes due and payable as therein or herein provided, whether on the Maturity Date or by declaration of acceleration, exercise of the repurchase right set forth in Article 11 or otherwise. 
  
 “Maturity Date” means, with respect to the Notes, December 15, 2037.

  
 “Measurement
Period” (i) for purposes of determining whether the Company is required to pay Contingent Interest, has the meaning specified in Section 3.03(a) and (ii) for purposes of determining whether the Trading Price Condition has
been met, the meaning specified in Section 12.01(a)(i). 
  
 “Merger Event” has the meaning specified in Section 12.10. 
  

“Net Share Settlement Election” has the meaning specified in Section 12.02(b). 

 
 “Notes” has the meaning
ascribed to it in the first paragraph under the caption “Recitals of the Company.” Unless the context otherwise requires, all references to the Notes shall include the Initial Notes and any Additional Notes. 

 
 “Notice of Conversion” has
the meaning specified in Section 12.02(d). 
  
 “Observation Period” means, with respect to any Notes, 
  

(a) with respect to any Conversion Date occurring on or after the 35th Scheduled Trading Day prior to the Maturity Date of the Notes, the
30 consecutive VWAP Trading Day period beginning on, and including, the 32nd Scheduled Trading Day prior to the Maturity Date (or if such day is not a VWAP Trading Day, the next succeeding VWAP Trading Day); and 

 
 (b) in all other instances, the 30
consecutive VWAP Trading Day period beginning on and including the third VWAP Trading Day after the related Conversion Date in respect of such Notes. 
  

“Opinion of Counsel” means a written opinion of counsel, who may be an employee of or counsel to the
Company, and who shall be reasonably acceptable to the Trustee. 
  
 “Optional Put Repurchase Offer” has the meaning specified in Section 11.08(a)(ii). 
  

“Optional Put Repurchase Date” has the meaning specified in Section 11.08(a)(i). 

 
 “Optional Put Repurchase
Notice” has the meaning specified in Section 11.08(a)(ii). 
  
 “Optional Put Repurchase Price” has the meaning specified in Section 11.08(a)(i). 

  
 8 








 “Original Principal Amount” means (a) with respect to
the Initial Notes, the principal amount of the Initial Notes as of the Issue Date and (b) with respect to Additional Notes, if any, the principal amount of such Additional Notes on their date of issuance. 

 
 “Outstanding,” when used
with respect to the Notes, means, as of the date of determination, all Notes theretofore authenticated and delivered under this Supplemental Indenture, except: 
  

(i) Notes theretofore canceled by the Trustee or delivered to the Trustee for cancellation; 

 
 (ii) Notes for the payment of which money in
the necessary amount has been theretofore deposited with the Trustee or any Paying Agent (other than the Company) in trust or set aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent) for the Holders of such
Notes in accordance with the terms of this Supplemental Indenture; 
  
 (iii) Notes which have been paid pursuant to Section 3.09 or in exchange for or in lieu of which other Notes have been authenticated and delivered pursuant to this Supplemental Indenture; 

 
 (iv) Notes converted into Common Stock
pursuant to Article 12; and 
  
 (v)
Notes redeemed or repurchased pursuant to Article 11; 
  
 provided, however, that, in determining whether the Holders of the requisite principal amount of Outstanding Notes are present at a meeting of Holders for quorum purposes or have given any
request, demand, authorization, direction, notice, consent or waiver hereunder, Notes owned by the Company or any other obligor upon the Notes or any Affiliate of the Company or such other obligor shall be disregarded and deemed not to be
Outstanding, except that, in determining whether the Trustee shall be protected in relying upon any such determination as to the presence of a quorum or upon any such request, demand, authorization, direction, notice, consent or waiver, only Notes
which a Responsible Officer of the Trustee has been notified in writing to be so owned shall be so disregarded. Notes so owned which have been pledged in good faith may be regarded as Outstanding if the pledgee is not the Company or any other
obligor upon the Notes or any Affiliate of the Company or such other obligor, and the Trustee shall be protected in relying upon an Officers’ Certificate to such effect. 

 
 “Paying Agent” means any
Person authorized by the Company to pay the principal of or Interest on any Notes on behalf of the Company and, except as otherwise specifically set forth herein, such term shall include the Company if it shall act as its own Paying Agent. The
Company has initially appointed the Trustee as its Paying Agent pursuant to Section 10.02. 
  

“Person” means any individual, corporation, limited liability company, partnership, joint venture, trust,
estate, unincorporated organization or government or any agency or political subdivision thereof and any syndicate or group that would be deemed a “person” under Section 13(d)(3) of the Exchange Act. 

  
 9 








 “Place of Payment” has the meaning specified in
Section 3.01(e). 
  

“Predecessor Note” of any particular Note means every previous Note evidencing all or a portion of the
same debt as that evidenced by such particular Note; and, for the purposes of this definition, any Note authenticated and delivered under Section 3.09 in exchange for or in lieu of a mutilated, destroyed, lost or stolen Note shall be deemed to
evidence the same debt as the mutilated, destroyed, lost or stolen Note. 
  
 “Press Release” means any press release issued by the Company and disseminated to a reputable national newswire service. 
  
 “Record Date” means any Regular Record Date or Special Record Date.

  
 “Redemption
Date” when used with respect to any Note to be redeemed, means the date fixed for such redemption pursuant to this Indenture. 
  

“Redemption Price” has the meaning specified in Section 11.01. 

 
 “Reference Property” has
the meaning specified in Section 12.10. 
  
 “Registrar” means the Trustee, for the purpose of registering Notes and transfers of Notes. 
  

“Regular Interest” has the meaning specified in Section 3.02. 

 
 “Regular Record Date” for
Interest payable in respect of any Note on any Interest Payment Date means 5:00 p.m. New York time on June 1 or December 1 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date. 

 
 “Scheduled Trading Day”
means a day that is scheduled to be a Trading Day on the principal United States national or regional securities exchange or market on which the Common Stock is listed or admitted for trading or, if the Common Stock is not listed or admitted for
trading on any exchange or market, a Business Day. 
  
 “Securities Act” means the Securities Act of 1933 and any statute successor thereto, in each case as amended from time to time. 
  
 “Significant Subsidiary” means, with respect to any Person, a Subsidiary of
such Person that would constitute a “significant subsidiary” as such term is defined under Rule 1-02 of Regulation S-X under the Securities Act and the Exchange Act. 

 
 “Special Record Date” for
the payment of any Defaulted Interest means a date fixed by the Trustee pursuant to Section 3.10. 
  

“Specified Dollar Amount” means a dollar amount of cash to be delivered per $1,000 Original Principal
Amount of Notes specified in a notice pursuant to Section 12.02. 
  
 “Spin-Off” has the meaning specified in Section 12.04(c). 

  
 10 









 “Stock Price” means the price per share of Common Stock at
the time of a Make-Whole Fundamental Change pursuant to which Additional Shares shall be added to the Conversion Rate as set forth in Section 12.01(e), which shall be equal to (i) if holders of Common Stock receive only cash consideration
for their shares of Common Stock in connection with a Make-Whole Fundamental Change, the cash amount paid per share of Common Stock and (ii) in all other cases, the average of the Daily VWAP of the Common Stock over the 10 VWAP Trading Day
period ending on the Trading Day preceding the effective date of such Make-Whole Fundamental Change. 
  

“Supplemental Indenture” has the meaning specified in the first paragraph of this instrument. 

 
 “Trading Day” means a day
during which (i) trading in the Common Stock generally occurs and (ii) there is no Market Disruption Event. 
  

“Trading Price” with respect to any Notes, on any date of determination, means the average of the
secondary market bid quotations obtained by the Trustee for $2.0 million in Original Principal Amount of such Notes at approximately 3:30 p.m., New York City time, on such determination date from three independent nationally recognized securities
dealers selected by the Company; provided that if three such bids cannot reasonably be provided (in the reasonable judgment of the Company) to the Trustee, but two such bids are obtained, then the average of the two bids shall be used, and if
only one such bid is obtained, that one bid shall be used. If at least one bid for $2.0 million in Original Principal Amount of the Notes cannot reasonably be obtained, then the trading price per $1,000 in principal amount of Notes shall be deemed
to be less than 98% of the product of the Last Reported Sale Price of the Common Stock and the applicable Conversion Rate. Any such determination shall be conclusive absent manifest error. Notwithstanding the foregoing, for purposes of
Section 3.03 only, if two bids for $2.0 million in Original Principal Amount of the Notes cannot reasonably be provided (in the reasonable judgment of the Company) to the Trustee, from nationally recognized securities dealers selected by the
Company, but one such bid can reasonably be obtained (in the reasonable judgment of the Company) by the Trustee, this one bid shall be used. If at least one bid for $2.0 million in Original Principal Amount of the Notes cannot reasonably be provided
(in the reasonable judgment of the Company) to the Trustee, from a nationally recognized securities dealer or in the Company’s reasonable judgment the bid quotations are not indicative of the secondary market value of the Notes, then the
Trading Price of the Notes will be deemed to equal the product of (x) the Conversion Rate then in effect and (y) the average closing sales price of Common Stock over the five Trading Day period ending on such determination date.

  
 “Trading Price
Condition” has the meaning specified in Section 12.01(a)(i). 
  
 “Trigger Event” has the meaning specified in Section 12.04(c). 
  

“Trust Indenture Act” means the Trust Indenture Act of 1939 as in force at the date as of which this
instrument was executed; provided, however, that in the event the Trust Indenture Act of 1939 is amended after such date, “Trust Indenture Act” means, to the extent required by any such amendment, the Trust Indenture Act of 1939 as
so amended. 

  
 11 









 “Trustee” means the Person named as the “Trustee”
in the first paragraph of this instrument until a successor Trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean such successor Trustee. 

 
 “VWAP Market Disruption
Event” means (i) a failure by the principal U.S. national or regional securities exchange or market on which the Common Stock is listed or admitted to trading to open for trading during its regular trading session or (ii) the
occurrence or existence prior to 1:00 p.m., New York City time, on any Scheduled Trading Day for the Common Stock for an aggregate one half-hour period of any suspension or limitation imposed on trading, by reason of movements in price exceeding
limits imposed by the stock exchange or otherwise, in the Common Stock or in any options contracts or futures contracts relating to the Common Stock. 
  

“VWAP Trading Day” means a day during which (i) trading in the Common Stock generally occurs during
the regular trading session on the principal U.S. national or regional securities exchange or market on which the Common Stock is listed or admitted for trading and (ii) there is no VWAP Market Disruption Event. If the Common Stock is not so
listed or traded, then VWAP Trading Day means a Business Day. 
  
 SECTION 1.02 [Reserved.] 
  
 SECTION 1.03 [Reserved.] 
  
 SECTION 1.04 Effect of Headings and Table of Contents. 
  

The Article and Section headings herein and the Table of Contents are for convenience only and shall not affect the
construction hereof. 
  
 SECTION 1.05
[Reserved.] 
  
 SECTION 1.06
[Reserved.]. 
  
 SECTION 1.07
[Reserved.] 
  
 SECTION 1.08
Conflict With Trust Indenture Act. 
  
 If any provision hereof limits, qualifies or conflicts with a provision of the Trust Indenture Act that is made applicable to this Supplemental Indenture, the latter provision shall control. If any
provision of this Supplemental Indenture modifies or excludes any provision of the Trust Indenture Act that is made applicable to this Supplemental Indenture, the latter provision shall be deemed to apply to this Supplemental Indenture as so
modified or to be excluded, as the case may be. 
  

SECTION 1.09 Successors and Assigns. 

 
 All covenants and agreements in this
Supplemental Indenture by the Company shall bind its successors and assigns, whether so expressed or not. 

  
 12 









 SECTION 1.10 Separability Clause. 

 
 In case any provision in this Supplemental
Indenture or in the Notes shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 

 
 SECTION 1.11 Benefits of Indenture.

  
 Nothing in this Supplemental
Indenture or in the Notes, express or implied, shall give to any Person, other than the parties hereto and their successors hereunder and the Holders, any benefit or any legal or equitable right, remedy or claim under this Supplemental Indenture.

  
 SECTION 1.12 Governing Law.

  
 This Supplemental Indenture and
the Notes shall be governed by and construed in accordance with the laws of the State of New York. 
  
 SECTION 1.13 Legal Holidays. 
  

In any case where any Interest Payment Date, Redemption Date, Optional Put Repurchase Date, Fundamental Change Repurchase
Date or the Maturity Date of any Note or the last date on which a Holder has the right to convert his Notes shall not be a Business Day, then (notwithstanding any other provision of this Supplemental Indenture or of the Notes) payment of Interest or
principal or conversion of the Notes need not be made on such date, but may be made on the next succeeding Business Day with the same force and effect as if made on the Interest Payment Date, Redemption Date, Optional Put Repurchase Date or
Fundamental Change Repurchase Date, or at the Maturity Date, or on such last day for conversion, provided that no Interest shall accrue for the period from and after such Interest Payment Date, Redemption Date, Optional Put Repurchase Date,
Fundamental Change Repurchase Date or the Maturity Date, as the case may be. Notwithstanding the foregoing, the right to convert a Note shall cease at the close of business on the third Scheduled Trading Day immediately preceding the Maturity Date.

  
 SECTION 1.14 [Reserved.]

  
 SECTION 1.15 Relationship with
Base Indenture. 
  
 The terms
and provisions contained in the Base Indenture shall constitute, and are hereby expressly made, a part of this Supplemental Indenture and the Company and the Trustee, by their execution and delivery of this Supplemental Indenture, expressly agree to
such terms and provisions and to be bound thereby. However, to the extent any provision of the Base Indenture conflicts with the express provisions of this Supplemental Indenture, the provisions of this Supplemental Indenture shall govern and be
controlling. 
  
 The Trustee accepts
the amendment of the Base Indenture effected by this Supplemental Indenture and agrees to execute the trust created by the Base Indenture as hereby amended, but only upon the terms and conditions set forth in the Indenture, including the terms and
provisions defining and limiting the liabilities and responsibilities of the Trustee in the performance of the 

  
 13 









 
trust created by the Base Indenture, and without limiting the generality of the foregoing, the Trustee shall not be responsible in any manner whatsoever for or with respect to any of the recitals
or statements contained herein, all of which recitals or statements are made solely by the Company, or for or with respect to (1) the validity or sufficiency of this Supplemental Indenture or any of the terms or provisions hereof, (2) the
proper authorization hereof by the Company, (3) the due execution hereof by the Company or (4) the consequences (direct or indirect and whether deliberate or inadvertent) of any amendment herein provided for, and the Trustee makes no
representation with respect to any such matters. 
  

ARTICLE 2 

NOTE FORMS 
  

SECTION 2.01 Form Generally. 
  

The Notes shall be in substantially the form set forth in this Article 2, with such appropriate insertions, omissions,
substitutions and other variations as are required or permitted by this Supplemental Indenture, and may have such letters, numbers or other marks of identification and such legends or endorsements placed thereon as may be required to comply with the
rules of any securities exchange, the Code, and regulations thereunder, or as may, consistent herewith, be determined by the officers executing such Notes, as evidenced by their execution thereof. The Company shall furnish any such legends and
endorsements to the Trustee in writing. All Notes shall be in fully registered form. 
  

Notices of Conversion shall be in substantially the form set forth in Section 2.03. 

 
 The Notes shall be printed, lithographed,
typewritten or engraved or produced by any combination of these methods or may be produced in any other manner permitted by the rules of any automated quotation system or securities exchange (including on steel engraved borders if so required by any
securities exchange upon which the Notes may be listed) on which the Notes may be listed for trading, as the case may be, all as determined by the officers executing such Notes, as evidenced by their execution thereof. 

 
 SECTION 2.02 Form of Note. 

 
 [FORM OF FACE OF NOTE] 

 
 The following legend shall appear on the face
of each Global Note: 
  
 THIS
NOTE IS A GLOBAL NOTE WITHIN THE MEANING OF THE SUPPLEMENTAL INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF THE DEPOSITARY OR A NOMINEE OF THE DEPOSITARY, WHICH MAY BE TREATED BY THE COMPANY, THE TRUSTEE AND ANY AGENT THEREOF AS
OWNER AND HOLDER OF THIS NOTE FOR ALL PURPOSES. 

  
 14 









 UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF
THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME
AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE
BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
  

UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR NOTES IN DEFINITIVE REGISTERED FORM IN THE LIMITED
CIRCUMSTANCES REFERRED TO IN THE SUPPLEMENTAL INDENTURE, THIS GLOBAL NOTE MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE
DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY. 

  
 15 









 HOLOGIC, INC. 
 2.00% Convertible Exchange Senior Notes due 2037 
  
 No.                           

 
 CUSIP No. 436440 AB7 

 
 HOLOGIC, INC., a corporation duly organized
and existing under the laws of the State of Delaware (herein called the “Company,” which term includes any successor Person under the Supplemental Indenture referred to on the reverse hereof), for value received, hereby promises to
pay to                     , or registered assigns, the principal sum of
                     United States Dollars (U.S. $            ) [if this
Note is a Global Note, then insert — (which principal amount may from time to time be decreased to such other principal amounts by adjustments made on the records of the Registrar hereinafter referred to in accordance with the Supplemental
Indenture)] on December 15, 2037 (the “Maturity Date”), and to pay interest thereon, from                     , or from the
most recent Interest Payment Date (as defined below) to which interest has been paid or duly provided for, semi-annually in arrears on June 15 and December 15 in each year (each, an “Interest Payment Date”), commencing
                     at the rate of 2.00% per annum. The Notes will cease to bear interest (except Contingent Interest, as applicable) on
December 15, 2016, and instead from such date the principal amount of the Notes will accrete at a rate that provides Holders with an aggregate annual yield to maturity of 2.00% per year (computed on a semi-annual bond-equivalent basis).
The interest so payable, and punctually paid or duly provided for, on any Interest Payment Date shall, as provided in the Indenture, be paid to the Person in whose name this Note (or one or more Predecessor Notes) is registered at the close of
business on the Regular Record Date for such interest, which shall be the June 1 or December 1 (whether or not a Business Day), as the case may be, next preceding such Interest Payment Date. Except as otherwise provided in the Supplemental
Indenture, any such interest not so punctually paid or duly provided for shall forthwith cease to be payable to the Holder on such Regular Record Date and may either be paid to the Person in whose name this Note (or one or more Predecessor Notes) is
registered at the close of business on a Special Record Date for the payment of such Defaulted Interest to be fixed by the Trustee pursuant to Section 3.10 of the Supplemental Indenture, notice whereof shall be given to Holders not less than 10
calendar days prior to the Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of any automated quotation system or securities exchange on which the Notes may then be listed for trading, and
upon such notice as may be required by such exchange, all as more fully provided in the Supplemental Indenture. Payments of principal shall be made upon the surrender of this Note by the Holder thereof at the Corporate Trust Office of the Trustee,
or at such other office or agency of the Company as may be designated by it for such purpose in such lawful monies of the United States of America as at the time of payment shall be legal tender for the payment of public and private debts, or at
such other offices or agencies as the Company may designate. All amounts due in cash with respect to the Notes shall be paid (A) in the case this Note is in global form, by wire transfer of immediately available funds to the account designated
by the Depositary or its nominee; (B) in the case this Note is held, other than in global form, by a Holder in an aggregate principal amount of $5.0 million or less, by check mailed to such Holders; and (C) in the case this Note is held,
other than in global form, by a Holder in an aggregate principal amount of more than $5.0 million, either by check mailed to 

  
 16 









 
such Holder or, upon application by such Holder to the Registrar not later than the relevant record date (in the case of an installment of interest due on an Interest Payment Date) or 15 calendar
days prior to such other date on which such amounts are due, by wire transfer in immediately available funds to such Holder’s account within the United States, which application shall remain in effect until the Holder notifies, in writing, the
Registrar to the contrary. 
  
 The
Notes were issued with original issue discount for United States federal income tax purposes. The Company agrees, and by acceptance of a beneficial ownership interest in the Notes each Holder is deemed to have agreed, for United States federal
income tax purposes, (a) to treat the Notes as indebtedness subject to United States Treasury Regulations Section 1.1275-4 (the “Contingent Payment Debt Regulations”) and, for purposes of the Contingent Payment Debt
Regulations, to treat cash and the fair market value of any Common Stock beneficially received by a Holder upon conversion of such Note as a contingent payment under Treasury Regulation Section 1.1275-4(b); (b) to be bound by the
Company’s application of the Contingent Payment Debt Regulations to the Notes, including the Company’s determination of the comparable yield and projected payment schedule, as defined in the Contingent Payment Debt Regulations, with
respect to the Notes; and (c) to use such comparable yield and projected payment schedule in determining interest accruals with respect to such Holder’s Notes and in determining adjustments thereto. A Holder may obtain the issue price,
Issue Date, comparable yield (which will be treated as the yield to maturity for United States federal income tax purposes) and projected payment schedule by submitting a written request to the Company at the following address: Hologic, Inc., 35
Crosby Drive, Bedford, Massachusetts 01730, Attention: Investor Relations. 
  
 Except as specifically provided herein and in the Supplemental Indenture, the Company shall not be required to make any payment with respect to any tax, assessment or other governmental charge imposed by
any government or any political subdivision or taxing authority thereof or therein. 
  

Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions
shall for all purposes have the same effect as if set forth at this place. 
  
 Unless the certificate of authentication hereon has been executed by the Trustee referred to on the reverse hereof or an Authenticating Agent by the manual signature of one of their respective authorized
signatories, this Note shall not be entitled to any benefit under the Supplemental Indenture or be valid or obligatory for any purpose. 
  

[Remainder of page intentionally left blank] 

  
 17 









 IN WITNESS WHEREOF, the Company has caused this Note to be duly executed.

  

					
	HOLOGIC, INC.
		
	By:	 	  

		 	Name:	 	
		 	Title:	 	


  

					
	 Attest:

		
	 By:
	  	  

		  	Name:	 	
		  	Title:	 	

  
 TRUSTEE’S
CERTIFICATE OF AUTHENTICATION 
  
 This is one of the
Notes referred to in the within-mentioned Supplemental Indenture. 
  

			
	 Dated:
	 	  



 

			
	 WILMINGTON TRUST COMPANY,

as Trustee

		
	 By:
	  	  

		  	Authorized Signatory


  
 18 









 [FORM OF REVERSE OF NOTE] 
  
 HOLOGIC, INC. 
 2.00% Convertible Exchange Senior Notes due 2037 
  

This Note is one of a duly authorized issue of Notes of the Company designated as its “2.00% Convertible Exchange
Senior Notes due 2037” (herein called the “Notes”) issued and to be issued under the Indenture (the “Base Indenture”), dated as of December 10, 2007, between the Company and Wilmington Trust Company,
as Trustee (herein called the “Trustee,” which term includes any successor trustee under the Indenture (as defined below)), as supplemented and modified by the Second Supplemental Indenture (the “Supplemental
Indenture” and, together with the Base Indenture, the “Indenture”), dated as of November 23, 2010, between the Company and the Trustee, to which Indenture and all indentures supplemental thereto reference is hereby
made for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Company, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be, authenticated and delivered. As
provided in the Supplemental Indenture and subject to certain limitations therein set forth, the Notes are exchangeable for a like aggregate Accreted Principal Amount of Notes of any authorized denominations as requested by the Holder surrendering
the same upon surrender of the Note or Notes to be exchanged, at the Corporate Trust Office of the Trustee. The Trustee upon such surrender by the Holder hereof and the satisfaction of any requirements therefor set forth in the Supplemental
Indenture shall issue the new Notes in the requested denominations. Additional Notes may be issued in an unlimited aggregate principal amount, subject to certain conditions specified in the Supplemental Indenture. 

 
 No sinking fund is provided for in the
Notes. 
  
 In any case where any
Interest Payment Date, Redemption Date, Optional Put Repurchase Date, Fundamental Change Repurchase Date or the Maturity Date of any Note or the last date on which a Holder has the right to convert his Notes shall not be a Business Day, then
(notwithstanding any other provision of the Supplemental Indenture or of the Notes) payment of Interest or Accreted Principal Amount or conversion of the Notes need not be made on such date, but may be made on the next succeeding Business Day with
the same force and effect as if made on the Interest Payment Date, Redemption Date, Optional Put Repurchase Date or Fundamental Change Repurchase Date, or at the Maturity Date, or on such last day for conversion, provided that no Interest
shall accrue for the period from and after such Interest Payment Date, Redemption Date, Optional Put Repurchase Date, Fundamental Change Repurchase Date or the Maturity Date, as the case may be. 

 
 The Supplemental Indenture contains
provisions permitting the Company and the Trustee in certain circumstances, without the consent of the Holders of the Notes, and in other circumstances, with the consent of the Holders of not less than a majority in aggregate Accreted Principal
Amount of the Notes at the time outstanding, evidenced as in the Supplemental Indenture provided, to execute supplemental indentures adding any provisions to or changing in any manner or eliminating any of the provisions of the Supplemental
Indenture or of any supplemental indenture or modifying in any manner the rights of the Holders of the Notes; 

  
 19 









 
provided, however, that no such supplemental indenture shall make any of the changes set forth in Section 8.02 of the Supplemental Indenture, without the consent of each Holder
of an outstanding Note affected thereby. It is also provided in the Supplemental Indenture that, prior to any declaration accelerating the maturity of the Notes, the Holders of a majority in Accreted Principal Amount of the Notes at the time
outstanding may on behalf of the Holders of all of the Notes waive any past Default or Event of Default under the Supplemental Indenture and its consequences except as provided in the Supplemental Indenture. Any such consent or waiver by the Holder
of this Note (unless revoked as provided in the Supplemental Indenture) shall be conclusive and binding upon such Holder and upon all future holders and owners of this Note and any Notes which may be issued in exchange or substitution hereof,
irrespective of whether or not any notation thereof is made upon this Note or such other Notes. 
  

No reference herein to the Supplemental Indenture and no provision of this Note or of the Supplemental Indenture shall
alter or impair the obligation of the Company, which is absolute and unconditional, to pay the Accreted Principal Amount of, and accrued and unpaid Interest on, this Note, at the place, at the respective times, at the rate and in the lawful money
herein prescribed. 
  
 Subject to
the provisions of the Supplemental Indenture, upon the occurrence of a Fundamental Change or on an Optional Put Repurchase Date, the Holder has the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s
Notes or any portion thereof (in Original Principal Amounts of $1,000 or integral multiples thereof) on the Fundamental Change Repurchase Date or Optional Put Repurchase Date, as applicable, at a price equal to 100% of the Accreted Principal Amount
of the Notes such Holder elects to require the Company to repurchase, together with accrued and unpaid Interest to, but excluding, the Fundamental Change Repurchase Date or Optional Put Repurchase Date, as applicable, unless such Fundamental Change
Repurchase Date or Optional Put Repurchase Date, as applicable, falls after a Regular Record Date and on or prior to the corresponding Interest Payment Date, in which case the Company shall pay the full amount of accrued and unpaid Interest payable
on such Interest Payment Date to the Holder of record at the close of business on the corresponding Regular Record Date. No later than 20 Business Days prior to each Optional Put Repurchase Date, the Company shall give notice to each Holder (and to
beneficial owners as required by applicable law) of their related repurchase right. The Company or, at the written request of the Company, the Trustee shall mail to all Holders of record of the Notes a notice of the occurrence of a Fundamental
Change and of the repurchase right arising as a result thereof after the occurrence of any Fundamental Change, but on or before the 10th calendar day following such occurrence. 

 
 The Holder hereof has the right, at its
option, (i) upon the occurrence of certain conditions specified in the Supplemental Indenture, at any time prior to the close of business on the Scheduled Trading Day immediately preceding September 15, 2037, or (ii) on or after
September 15, 2037, at any time prior to the close of business on the second Scheduled Trading Day immediately preceding the Maturity Date, to convert any Notes or portion thereof which is $1,000 in Original Principal Amount or an integral
multiple thereof, into shares of Common Stock (or cash or combination of cash and shares of Common Stock, at the election of the Company, as set forth in Section 12.02 of the Supplemental Indenture) or Reference Property, in


  
 20 









 
each case at the Conversion Rate specified in the Supplemental Indenture, as adjusted from time to time as provided in the Supplemental Indenture, upon satisfaction of certain requirements set
forth in the Supplemental Indenture, including, if applicable, the surrender of this Note, together with a Notice of Conversion, a form of which is contained under Section 2.03 of the Supplemental Indenture, as provided in the Supplemental
Indenture and this Note, to the Company at the office or agency of the Company maintained for that purpose, or at the option of such Holder, the Corporate Trust Office, and, unless the shares of Common Stock or Reference Property, as the case may
be, issuable on conversion are to be issued in the same name as this Note, duly endorsed by, or accompanied by instruments of transfer in form satisfactory to the Company duly executed by, the Holder or by his duly authorized attorney. The initial
Conversion Rate shall be 43.4216 shares of Common Stock for each $1,000 in Original Principal Amount of Notes. No fractional shares of Common Stock or Reference Property, as the case may be, shall be issued upon any conversion, but an adjustment in
cash shall be paid to the Holder, as provided in the Supplemental Indenture, in respect of any fraction of such share which would otherwise be issuable upon the surrender of any Note or Notes for conversion. No adjustment shall be made for dividends
or any such shares issued upon conversion of such Notes except as provided in the Supplemental Indenture. 
  

Upon due presentment for registration of transfer of this Note at the office or agency of the Company, a new Note or Notes
of authorized denominations for an equal aggregate Accreted Principal Amount shall be issued to the transferee in exchange thereof, subject to the limitations provided in the Supplemental Indenture, without charge except for any tax, assessments or
other governmental charge imposed in connection therewith. 
  
 The Company, the Trustee, any Authenticating Agent, any Paying Agent, any Conversion Agent and any Registrar may deem and treat the registered Holder hereof as the absolute owner of this Note (whether or
not this Note shall be overdue and notwithstanding any notation of ownership or other writing hereon), for the purpose of receiving payment hereof, or on account hereof, for the conversion hereof and for all other purposes, and neither the Company
nor the Trustee nor any other authenticating agent nor any Paying Agent nor any other Conversion Agent nor any Registrar shall be affected by any notice to the contrary. All payments made to or upon the order of such registered Holder shall, to the
extent of the sum or sums paid, satisfy and discharge liability for monies payable on this Note. 
  

No recourse for the payment of the Accreted Principal Amount of, or accrued and unpaid Interest on, this Note, or for any
claim based hereon or otherwise in respect hereof, and no recourse under or upon any obligation, covenant or agreement of the Company in the Supplemental Indenture or any indenture supplemental thereto or in any Note, or because of the creation of
any Indebtedness represented thereby, shall be had against any incorporator, stockholder, employee, agent, officer, director or subsidiary, as such, past, present or future, of the Company or of any successor corporation, either directly or through
the Company or any successor corporation, whether by virtue of any constitution, statute or rule of law or by the enforcement of any assessment or penalty or otherwise, all such liability being, by the acceptance hereof and as part of the
consideration for the issue hereof, expressly waived and released. 

  
 21 









 Terms used in this Note and defined in the Supplemental Indenture are used
herein as therein defined. 
  
 In
the case of any conflict between the provisions of this Note and the Indenture, the provisions of the Indenture shall control. 
  

The Indenture and this Note shall be governed by and construed in accordance with the laws of the State of New York.

  
 Customary abbreviations may
be used in the name of a Holder or an assignee, such as TEN COM (=tenants in common), TENANT (=tenants by the entireties), JT TEN (joint tenants with right of survivorship and not as tenants in common), CUST (=custodian), and U/G/M/A (=Uniform gift
to Minors Act). 

  
 22 









 FORM OF OPTIONAL PUT REPURCHASE NOTICE AND FUNDAMENTAL 

CHANGE REPURCHASE NOTICE 
  

To: Hologic, Inc. 
  

The undersigned registered owner of this Note hereby acknowledges receipt of a notice from Hologic, Inc. (the
“Company”) as to the occurrence of (check the appropriate box): 
  

			
	 ̈      a Fundamental Change with respect to the Company;
	
	 ̈      an Optional Put Repurchase Date;


 
 and hereby directs the Company to pay, or cause the Trustee
to pay, it or                      an amount in cash equal to 100% of the Accreted Principal Amount, or the portion thereof (which is $1,000
in Original Principal Amount or an integral multiple thereof) below designated, to be repurchased plus interest accrued to, but excluding, the Optional Put Repurchase Date or the Fundamental Change Repurchase Date, as applicable, except as provided
in the Supplemental Indenture. 
  

			
	 Dated:

	  

	
	  

	  

Signature(s)
  

Signature(s) must be guaranteed by an Eligible Guarantor Institution with membership in an approved signature guarantee program
pursuant to Rule 17Ad-15 under the Securities Exchange Act of 1934.


	
	  

	 Signature Guaranteed

	
	 Certificate number(s), if applicable, of Note(s) tendered for repurchase:
                    


	
	 Principal amount to be repurchased (at least U.S. $1,000 Original Principal Amount or an integral multiple of $1,000 in excess thereof):
                    

	
	 Remaining principal amount following such repurchase (not less than U.S. $1,000 Original Principal Amount):

		
	 By:
	 	  

		 	Authorized Signatory


  
 23 









 SECTION 2.03 Form of Notice of Conversion. 

 
 NOTICE OF CONVERSION 

 
 The undersigned Holder of this Note hereby
irrevocably exercises the option to convert this Note, or any portion of the Accreted Principal Amount hereof (which is U.S. $1,000 Original Principal Amount or an integral multiple of U.S. $1,000 in excess thereof, provided that the
unconverted portion of such Original Principal Amount is U.S. $1,000 or any integral multiple of U.S. $1,000 in excess thereof) below designated, into shares of Common Stock or Reference Property in accordance with the terms of the Supplemental
Indenture referred to in this Note, and directs that the consideration due upon such conversion (including a check in payment for any fractional share and any Notes representing any unconverted principal amount hereof), be delivered to and be
registered in the name of the undersigned unless a different name has been indicated below. If shares of Common Stock, Reference Property or Notes are to be registered in the name of a Person other than the undersigned, (a) the undersigned
shall pay all transfer taxes payable with respect thereto and (b) signature(s) must be guaranteed by an Eligible Guarantor Institution with membership in an approved signature guarantee program pursuant to Rule 17Ad-15 under the Securities
Exchange Act of 1934. Any amount required to be paid by the undersigned on account of interest accompanies this Note. 
  

											
		 	 Dated:
	 	  
	 		  	  

		 		 		 		  	Signature(s)	  	

  

			
		 	If shares or Notes are to be registered in the name of a Person other than the Holder, please print such Person’s name and address:
		
		 	  

		 	(Name)
		
		 	  

		 	  

		 	(Address)
		
		 	  

		 	Social Security or other Identification Number, if any
		
		 	  

		 	[Signature Guaranteed]

  

If only a portion of the Notes is to be converted, please indicate: 

 

	 	1.	Accreted Principal Amount to be converted: U.S. $
                     


  
 24 










	 	2.	Accreted Principal Amount and denomination of Notes representing unconverted Accreted Principal Amount to be issued:
                     

  

Amount: U.S.
$                     Denominations: U.S.
$                     
  

(U.S. $1,000 Original Principal Amount or any integral multiple of U.S. $1,000 in excess thereof, provided that the unconverted
portion of such principal amount is U.S. $1,000 Original Principal Amount or any integral multiple of U.S. $1,000 in excess thereof). 
  

SECTION 2.04 Form of Assignment. 

 
 ASSIGNMENT 

 
 For value received,
                     hereby sell(s), assign(s) and transfer(s) unto
                     (Please insert Social Security or other identifying number of assignee) the within note, and hereby irrevocably
constitutes and appoints                      as attorney to transfer the said note on the books of the Company, with full power of
substitution in the premises. 
  

															
		 	Dated:	 	  
	 		 		 	Signature(s)	 	  



 
 Signature(s) must be guaranteed by an
Eligible Guarantor Institution with membership in an approved signature guarantee program pursuant to Rule 17Ad-15 under the Securities Exchange Act of 1934. 

 

	
	  

	 Signature Guaranteed




  
 25 









 ARTICLE 3 
 THE NOTES 
  
 SECTION 3.01 Title And Terms. 
  
 (a) The Notes shall be known and designated as the “2.00% Convertible Exchange Senior Notes due 2037” of the Company. Their Maturity Date shall be December 15, 2037 and they shall
bear Regular Interest on the Original Principal Amount in accordance with Section 3.02. 
  
 (b) Commencing on or after December 15, 2016, Contingent Interest shall be paid, if applicable, in accordance with Section 3.03. 
  
 (c) Commencing on December 15, 2016, the Accreted Principal Amount shall increase in accordance with
Section 3.04. 
  
 (d) The Company shall pay
Interest on overdue Accreted Principal Amount at the rate borne by the Notes, and it shall pay Interest on overdue installments of Interest at the same rate, in each case to the extent lawful. 
  
 (e) The Notes shall be subject to repurchase by the Company at the option of the Holders as provided in
Section 11.08 and Section 11.09 hereof. 
  

(f) The Accreted Principal Amount of and Interest on the Notes shall be payable as provided in the form of Notes set forth in
Section 2.02. The Optional Put Repurchase Price or the Fundamental Change Repurchase Price, as applicable, shall be payable at such place as is identified in the Optional Put Repurchase Notice or the Fundamental Change Repurchase Right Notice,
as applicable, given pursuant to Section 11.08 and Section 11.09, respectively (such city in which the identified Paying Agent is located being herein called a “Place of Payment”). 

 
 (g) The Notes shall be senior unsecured obligations of the
Company and shall rank pari passu with all of the Company’s other senior unsecured obligations. 
  

(h) The Notes may be redeemed at the option of the Company prior to Maturity pursuant to Section 11.01 hereof. 

 
 (i) The Notes shall be convertible as provided in Article 12.

  
 (j) Article 14 of the Base Indenture shall not be
applicable to the Notes. 
  
 SECTION 3.02
Regular Interest. 
  
 Subject to the last paragraph of Section 3.10, Regular Interest will accrue on the Notes at the rate of 2.00% per year (“Regular Interest”) during any six-month period from and
including December 15th to and including
June 14th or from and including June 15th to and including December 14th (each, an “Interest Period”), commencing
December 15, 2010; provided that the initial Interest Period shall commence on November 23, 2010 and run to and including December 14, 2010. Regular Interest will be payable semi-annually in arrears on each Interest


  
 26 









 
Payment Date (subject to Section 1.13) to the Holder of record at the close of business on the Regular Record Date preceding such Interest Payment Date; provided that the Notes will
cease to accrue Regular Interest as of December 15, 2016. 
  
 SECTION 3.03 Contingent Interest. 
  
 (a) The Company will pay Contingent Interest in cash to Holders during any Interest Period beginning with the six-month Interest Period commencing December 15, 2016, during any Interest Period if the
Trading Price of the Notes for each of the five Trading Days ending on the second Trading Day immediately preceding the first day of the applicable Interest Period (as used in this Section, the “Measurement Period”) equals or
exceeds 120% of the Accreted Principal Amount of the Notes. 
  
 (b) During any Interest Period when Contingent Interest shall be payable with respect to the Notes, the Contingent Interest payable per $1,000 in Original Principal Amount of Notes will equal 0.40% of the
average Trading Price of $1,000 in Original Principal Amount of the Notes for the applicable Measurement Period. 
  

(c) The Company will promptly (and in any event prior to the applicable Interest Payment Date) notify Holders upon determination that they
will be entitled to receive Contingent Interest during an Interest Period. 
  
 (d) The Company shall pay Contingent Interest owed pursuant to this Section 3.03 for any Interest Period on the Interest Payment Date immediately succeeding the applicable Interest Period, to Holders
of the Notes as of the Regular Record Date related to such Interest Payment Date. 
  
 SECTION 3.04 Accretion. 
  

Commencing on December 15, 2016, the Original Principal Amount shall accrete at a rate that provides Holders with an
aggregate annual yield to Maturity of 2.00% per annum (computed on a semi-annual bond-equivalent yield basis). Schedule B hereto sets forth the Accreted Principal Amounts as of specified dates during the period from December 15,
2016 through the Maturity Date. 
  

SECTION 3.05 Denominations. 
  

The Notes shall be issuable only in registered form, without coupons, in denominations of U.S. $1,000 of Original
Principal Amount and integral multiples of U.S. $1,000 in excess thereof. 
  
 SECTION 3.06 Execution, Authentication, Delivery and Dating. 
  

The Notes shall be executed on behalf of the Company by its Chief Executive Officer, its President or one of its Vice
Presidents, attested by its Secretary or one of its Assistant Secretaries. The signature of any of these officers on the Notes may be manual or facsimile. 

  
 27 









 Notes bearing the manual or facsimile signatures of individuals who were at
any time the proper officers of the Company shall bind the Company, notwithstanding that such individuals or any of them have ceased to hold such offices prior to the authentication and delivery of such Notes or did not hold such offices at the date
of such Notes. 
  
 At any time and
from time to time after the execution and delivery of this Supplemental Indenture, the Company may deliver Notes executed by the Company to the Trustee for authentication, together with a Company Order for the authentication and delivery of such
Notes; and the Trustee in accordance with such Company Order shall authenticate and deliver such Notes as provided in this Indenture and not otherwise. 
  

Each Note shall be dated the date of its authentication. 
  
 No Note shall be entitled to any benefit under this Supplemental Indenture or be valid or
obligatory for any purpose unless there appears on such Note a certificate of authentication substantially in the form provided for herein executed by the Trustee by manual signature, and such certificate upon any Note shall be conclusive evidence,
and the only evidence, that such Note has been duly authenticated and delivered hereunder. 
  
 SECTION 3.07 Global Notes; Non-Global Notes; Book-entry Provisions. 
  

(a) Global Notes 
  

(i) Each Global Note issued and authenticated under this Supplemental Indenture shall be registered in the name of the
Depositary designated by the Company for such Global Note or a nominee thereof and delivered to such Depositary or a nominee thereof or custodian therefor, and each such Global Note shall constitute a single Note for all purposes of this Indenture.
The Company hereby appoints DTC as the initial Depositary. 
  
 (ii) Except for exchanges of Global Notes for definitive, non-Global Notes at the sole discretion of the Company, no Global Note may be exchanged in whole or in part for Notes registered, and no transfer
of a Global Note in whole or in part may be registered, in the name of any Person other than the Depositary for such Global Note or a nominee thereof unless (A) such Depositary (i) has notified the Company that it is unwilling or unable to
continue as Depositary for such Global Note, or (ii) has ceased to be a clearing agency registered as such under the Exchange Act, has ceased to be a “clearing corporation” within the meaning of the Uniform Commercial Code, or
announces an intention permanently to cease business or does in fact do so or (B) there shall have occurred and be continuing an Event of Default with respect to such Global Note and the maturity of the Notes shall have been accelerated in
accordance with Section 5.02 and any Holder shall have given written notice to the Company requesting the issuance of definitive Notes. In such event set forth in clause (A) above, if a successor Depositary for such Global Note is not
appointed by the Company within 90 calendar days after the Company receives such notice or becomes aware of such ineligibility, the Company shall execute, and the Trustee, upon receipt of a Company Order directing the authentication and delivery of
Notes, shall authenticate and deliver, Notes, in any authorized denominations in an aggregate principal amount equal to the Accreted Principal Amount of such Global Note in exchange for such Global Note. 

  
 28 









 (iii) If any Global Note is to be exchanged for other Notes or canceled in
whole, it shall be surrendered by or on behalf of the Depositary or its nominee to the Trustee, as Registrar, for exchange or cancellation, as provided in this Article 3. If any Global Note is to be exchanged for other Notes or canceled in part, or
if another Note is to be exchanged in whole or in part for a beneficial interest in any Global Note, in each case as provided in this Article 3, then either (A) such Global Note shall be so surrendered for exchange or cancellation, as provided
in this Article 3, or (B) the Accreted Principal Amount thereof shall be reduced or increased by an amount equal to the portion thereof to be so exchanged or canceled, or equal to the principal amount of such other Note to be so exchanged for a
beneficial interest therein, as the case may be, by means of an appropriate adjustment made on the records of the Trustee, as Registrar, whereupon the Trustee, in accordance with the Applicable Procedures, shall instruct the Depositary or its
authorized representative to make a corresponding adjustment to its records. Upon any such surrender or adjustment of a Global Note, the Trustee shall, upon receipt of a Company Order, subject to this Article 3, authenticate and deliver any Notes
issuable in exchange for such Global Note (or any portion thereof) to or upon the order of, and registered in such names as may be directed by, the Depositary or its authorized representative. The Trustee shall be entitled to receive from the
Depositary the names, addresses and tax identification numbers of the Persons in whose names the Notes are to be registered prior to such authentication and delivery. Upon the request of the Trustee in connection with the occurrence of any of the
events specified in the preceding paragraph, the Company shall promptly make available to the Trustee a reasonable supply of Notes that are not in the form of Global Notes. The Trustee shall be entitled to rely upon any order, direction or request
of the Depositary or its authorized representative which is given or made pursuant to this Article 3 if such order, direction or request is given or made in accordance with the Applicable Procedures. 

 
 (iv) Every Note authenticated and delivered
upon registration of transfer of, or in exchange for or in lieu of, a Global Note or any portion thereof, whether pursuant to this Article 3 or otherwise, shall be authenticated and delivered in the form of, and shall be, a registered Global Note,
unless such Note is to be registered in accordance with this Article 3 in the name of a Person other than the Depositary for such Global Note or a nominee thereof, in which case such Note shall be authenticated and delivered in definitive, fully
registered form, without interest coupons. 
  
 (v) The Depositary or its nominee, as registered owner of a Global Note, shall be the Holder of such Global Note for all purposes under this Supplemental Indenture and the Notes, and owners of beneficial
interests in a Global Note shall hold such interests pursuant to the Applicable Procedures. Accordingly, any such owner’s beneficial interest in a Global Note shall be shown only on, and the transfer of such interest shall be effected only
through, records maintained by the Depositary or its nominee or its Agent Members and such owners of beneficial interests in a Global Note shall not be considered the owners or holders thereof. 

  
 29 









 (b) Non-Global Notes. Notes issued pursuant to Section 3.07(a)(ii) shall be in
definitive, fully registered form, without interest coupons. 
  
 SECTION 3.08 Persons Deemed Owners. 
  

Prior to due presentment of a Note for registration of transfer, the Company, the Trustee, any agent of the Company, the
Trustee or any Paying Agent may treat the Person in whose name such Note is registered as the owner of such Note for the purpose of receiving payment of principal of, and (subject to Section 3.10) Interest on, such Note, and for all other
purposes whatsoever, whether or not such Note be overdue, and none of the Company, the Trustee, any agent of the Company, the Trustee or any Paying Agent shall be affected by notice to the contrary. 

 
 SECTION 3.09 Mutilated, Destroyed, Lost and
Stolen Notes. 
  
 If any
mutilated Note is surrendered to the Trustee, the Company shall execute, and upon receipt of a Company Order, the Trustee shall authenticate and deliver in exchange therefor, a new Note of like tenor and Accreted Principal Amount and bearing a
number not contemporaneously outstanding. 
  
 If there shall be delivered to the Company and the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any Note and (ii) such security or indemnity as may be required
by them to save each of them and any agent of either of them harmless, then, in the absence of notice to the Company or the Trustee that such Note has been acquired by a bona fide purchaser, the Company shall execute, and upon receipt of a
Company Order, the Trustee shall authenticate and deliver, in lieu of any such destroyed, lost or stolen Note, a new Note of like tenor and principal amount and bearing a number not contemporaneously outstanding. 

 
 In case any such mutilated, destroyed, lost
or stolen Note has become or is about to become due and payable, the Company in its discretion may, instead of issuing a new Note, pay such Note. 
  

Upon the issuance of any new Note under this Section 3.09, the Company may require the payment of a sum sufficient to
cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected therewith. 

 
 Every new Note issued pursuant to this
Section 3.09 in lieu of any destroyed, lost or stolen Note shall constitute an original additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Note shall be at any time enforceable by anyone, and shall be
entitled to all the benefits of this Supplemental Indenture equally and proportionately with any and all other Notes duly issued hereunder. 
  

The provisions of this Section 3.09 are exclusive and shall preclude (to the extent lawful) all other rights and
remedies with respect to the replacement or payment of mutilated, destroyed, lost or stolen Notes. 

  
 30 









 SECTION 3.10 Payment of Interest; Interest Rights Preserved. 

 
 Interest on any Note which is payable, and
is punctually paid or duly provided for, on any Interest Payment Date shall be paid to the Person in whose name that Note (or one or more Predecessor Notes) is registered at the close of business on the Regular Record Date for such Interest.

  
 Any Interest on any Note which
is payable, but is not punctually paid or duly provided for, on any Interest Payment Date (herein called “Defaulted Interest”) shall forthwith cease to be payable to the Holder on the relevant Regular Record Date by virtue of having
been such Holder, and such Defaulted Interest may be paid by the Company, at its election in each case, as provided in clause (a) or (b) below: 
  

(a) The Company may elect to make payment of any Defaulted Interest to the Persons in whose names the Notes (or their respective
Predecessor Notes) are registered at the close of business on a special record date for the payment of such Defaulted Interest (a “Special Record Date”), which shall be fixed in the following manner. The Company shall notify the
Trustee in writing of the amount of Defaulted Interest proposed to be paid on each Note and the date of the proposed payment, and at the same time the Company shall deposit with the Trustee an amount of money equal to the aggregate amount proposed
to be paid in respect of such Defaulted Interest or shall make arrangements reasonably satisfactory to the Trustee for such deposit prior to the date of the proposed payment, such money when deposited to be held in trust for the benefit of the
Persons entitled to such Defaulted Interest as in this clause provided. Thereupon the Trustee shall fix a Special Record Date for the payment of such Defaulted Interest which shall be not more than 15 days and not less than 10 days prior to the date
of the proposed payment and not less than 10 days after the receipt by the Trustee of the notice of the proposed payment. The Trustee shall promptly notify the Company of such Special Record Date and, in the name and at the expense of the Company,
shall cause notice of the proposed payment of such Defaulted Interest and the Special Record Date therefor to be mailed, first-class postage prepaid, to each Holder at his address as it appears in the Securities Register, not less than 10 days prior
to such Special Record Date. Notice of the proposed payment of such Defaulted Interest and the Special Record Date therefor having been so mailed, such Defaulted Interest shall be paid to the Persons in whose names the Notes (or their respective
Predecessor Notes) are registered at the close of business on such Special Record Date and shall no longer be payable pursuant to the following Clause (b). 
  

(b) The Company may make payment of any Defaulted Interest in any other lawful manner not inconsistent with the requirements of any
securities exchange on which the Notes may be listed, and upon such notice as may be required by such exchange, if, after notice given by the Company to the Trustee of the proposed payment pursuant to this clause, such manner of payment shall be
deemed practicable by the Trustee. 
  

Subject to the foregoing provisions of this Section 3.10, each Note delivered under this Supplemental Indenture upon
registration of transfer of or in exchange for or in lieu of any other Note shall carry the rights to Interest accrued and unpaid, and to accrue, which were carried by such other Note, as provided for in this Indenture and the Notes. 

  
 31 









 SECTION 3.11 Cancellation. 

 
 All Notes surrendered for payment,
registration of transfer or exchange or conversion shall, if surrendered to any Person other than the Trustee, be delivered to the Trustee and shall be promptly cancelled by it. The Company may at any time deliver to the Trustee for cancellation any
Notes previously authenticated and delivered hereunder which the Company may have acquired in any manner whatsoever, and all Notes so delivered shall be promptly cancelled by the Trustee. No Notes shall be authenticated in lieu of or in exchange for
any Notes cancelled as provided in this Section 3.11, except as expressly permitted by this Supplemental Indenture. All cancelled Notes held by the Trustee shall be disposed of as directed by a Company Order. 

 
 SECTION 3.12 Computation of Interest.

  
 Interest on the Notes shall be
computed on the basis of a 360-day year of twelve 30-day months. 
  
 ARTICLE 4 
 DISCHARGE 

 
 SECTION 4.01 Discharge of Liability on
Notes. 
  
 When (1) the
Company shall deliver to the Registrar for cancellation all Notes then Outstanding not theretofore delivered to the Registrar for cancellation or (2) all the Notes then Outstanding not theretofore delivered to the Registrar for cancellation
shall have (a) been deposited for conversion and the Company shall deliver to the Holders shares of Common Stock (or, at the election of the Company, cash or a combination of cash and shares of Common Stock) sufficient to pay all amounts owing
in respect of all such Notes or (b) become due and payable on the Maturity Date, Redemption Date, Optional Put Repurchase Date, Fundamental Change Repurchase Date or otherwise, and the Company shall deposit with the Trustee cash sufficient to
pay all amounts owing in respect of all such Notes, including the Accreted Principal Amount and Interest accrued and unpaid to the Maturity Date, Redemption Date, Optional Put Repurchase Date, Fundamental Change Repurchase Date or other such date,
and if in either case of clauses (1) or (2) above, no Event of Default set forth in Section 5.01(h) or (i) hereof or event (including resulting from such deposit) that, with lapse of time or notice or both, would become an Event
of Default set forth in Section 5.01(h) or (i) hereof with respect to the Notes shall have occurred and be continuing, and the Company shall also pay or cause to be paid all other sums payable hereunder by the Company, then this
Supplemental Indenture with respect to the Notes shall cease to be of further effect (except as to (i) remaining rights of registration of transfer, substitution and exchange and conversion of Notes, (ii) rights hereunder of Holders to
receive from the Trustee payments of the amounts then due, including Interest with respect to the Notes and the other rights, duties and obligations of Holders, as beneficiaries hereof solely with respect to the amounts, if any, so deposited with
the Trustee, and (iii) the rights, obligations and immunities of the Trustee, Authenticating Agent, Paying Agent, Conversion Agent and Registrar under this Supplemental Indenture with respect to the Notes), and the Trustee, on demand of the
Company accompanied by an Officers’ Certificate and an Opinion of Counsel as required by Section 4.03 and at the cost and expense of the Company, shall execute proper instruments 

  
 32 









 
acknowledging satisfaction of, and discharging this Supplemental Indenture with respect to, the Notes; provided, however, the Company hereby agrees to reimburse the Trustee,
Authenticating Agent, Paying Agent, Conversion Agent and Registrar for any costs or expenses thereafter reasonably and properly incurred by the Trustee, Authenticating Agent, Paying Agent, Conversion Agent and Registrar and to compensate the
Trustee, Authenticating Agent, Paying Agent, Conversion Agent and Registrar for any services thereafter reasonably and properly rendered by the Trustee, Authenticating Agent, Paying Agent, Conversion Agent and Registrar in connection with this
Supplemental Indenture with respect to the Notes. 
  

SECTION 4.02 Reinstatement. 
  

If the Trustee or the Paying Agent is unable to apply any money to the Holders entitled thereto by reason of any order or
judgment of any court of governmental authority enjoining, restraining or otherwise prohibiting such application, the Company’s obligations under this Supplemental Indenture with respect to the Notes shall be revived and reinstated as though no
deposit had occurred pursuant to Section 4.01 until such time as the Trustee or the Paying Agent is permitted to apply all such money in accordance with this Supplemental Indenture and the Notes to the Holders entitled thereto; provided,
however, that if the Company makes any payment of the Accreted Principal Amount of or Interest on any Note following the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Notes to receive such
payment from the money held by the Trustee or Paying Agent. 
  
 SECTION 4.03 Officers’ Certificate; Opinion of Counsel. 
  

Upon any application or demand by the Company to the Trustee to take any action under Section 4.01, the Company shall
furnish to the Trustee an Officers’ Certificate and Opinion of Counsel stating that all conditions precedent, if any, provided for in this Supplemental Indenture relating to the proposed action have been complied with. 

 
 ARTICLE 5 

REMEDIES 
  

SECTION 5.01 Events of Default. 

 
 “Event of Default,”
wherever used herein, means any one of the following events with respect to the Notes (whatever the reason for such Event of Default or whether it shall be voluntary or involuntary or be effected by operation of law or pursuant to any judgment,
decree or order of any court or any order, rule or regulation of any administrative or governmental body): 
  

(a) default in any payment of Interest on any Note when due and payable and the default continues for a period of 30 calendar days; or

  
 (b) default in the payment of Accreted Principal
Amount of any Note when due and payable at Maturity, upon required repurchase, upon redemption, upon acceleration or otherwise; or 

  
 33 









 (c) failure by the Company for 5 calendar days to comply with its obligation to convert the
Notes into shares of Common Stock (or, at the election of the Company, cash or a combination of cash and shares of Common Stock) upon exercise of a Holder’s conversion right; or 
  
 (d) failure by the Company to comply with its obligations under Section 7.01; or 

 
 (e) failure by the Company to comply with its notice
requirements under Section 11.09(b) when due; or 
  
 (f) failure by the Company for 60 calendar days after written notice from the Trustee or the Holders of at least 25% aggregate Accreted Principal Amount of the Outstanding Notes has been received by the
Company to comply with any of its other agreements contained in the Notes or the Indenture; or 
  
 (g) default by the Company or any Subsidiary of the Company with respect to any mortgage, agreement or other instrument under which there may be outstanding, or by which there may be secured or evidenced,
any debt for money borrowed in excess of $100.0 million in the aggregate of the Company and/or any such Subsidiary of the Company, whether such debt now exists or shall hereafter be created, which default results (i) in such debt becoming or
being declared due and payable and such debt has not been discharged in full or such declaration rescinded or annulled within 30 calendar days or (ii) from a failure to pay the principal of any such debt when due and payable at its stated
maturity, upon required repurchase, upon declaration or otherwise, and such defaulted payments shall not have been made, waived or extended within 30 calendar days; or 

 
 (h) the Company shall commence a voluntary case or other
proceeding seeking liquidation, reorganization or other relief with respect to the Company or any of its Significant Subsidiaries or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the
appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any of its Significant Subsidiaries or any substantial part of its property, or shall consent to any such relief or to the appointment of or taking
possession by any such official in an involuntary case or other proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due; or 

 
 (i) an involuntary case or other proceeding shall be
commenced against the Company or any of its Significant Subsidiaries seeking liquidation, reorganization or other relief with respect to the Company or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or
seeking the appointment of a trustee, receiver, liquidator, custodian or other similar official of the Company or any of its Significant Subsidiaries or any substantial part of its property, and such involuntary case or other proceeding shall remain
undismissed and unstayed for a period of 60 consecutive calendar days. 
  
 (j) For the avoidance of doubt, Section 5.1 of the Base Indenture shall not be applicable to the Notes. 

  
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 SECTION 5.02 Acceleration of Maturity; Rescission and Annulment.

  
 If an Event of Default (other
than an Event of Default specified in Section 5.01(h) or Section 5.01(i) with respect to the Company) occurs and is continuing, then in every such case (except as provided in the immediately following paragraph) the Trustee or the Holders
of not less than 25% in aggregate Accreted Principal Amount of the Outstanding Notes may declare 100% of the aggregate Accreted Principal Amount of and accrued and unpaid Interest on all the Notes to be due and payable immediately, by a notice in
writing to the Company (and to the Trustee if given by the Holders), and upon any such declaration of acceleration, all principal and all accrued and unpaid Interest on the Notes shall become immediately due and payable. If an Event of Default
specified in Section 5.01(h) or Section 5.01(i) with respect to the Company occurs, the aggregate accreted principal of, and accrued and unpaid Interest, if any, on, all of the Notes shall become due and payable immediately without any
declaration or other Act of the Holders or any act on the part of the Trustee. 
  
 Notwithstanding the foregoing, at the election of the Company, the sole remedy of Holders for an Event of Default specified in Section 5.01(f) relating to the failure by the Company to comply with
its obligations under Section 10.06 and for any failure by the Company to comply with the requirements of Section 314(a)(1) of the Trust Indenture Act, shall for the first 90 calendar days after the occurrence of such an Event of Default
consist exclusively of the right (the “Extension Right”) to receive an extension fee on the Notes in an amount equal to 0.25% of the principal amount of the Notes (the “Extension Fee”). If the Company elects to pay
the Extension Fee as the sole remedy for an Event of Default specified in Section 5.01(f) relating to the failure by the Company to comply with its obligations under Section 10.06 and for any failure by the Company to comply with the
requirements of Section 314(a)(1) of the Trust Indenture Act, the Company (i) shall notify, in the manner provided for in Section 1.6 of the Base Indenture, the Holders, the Trustee and Paying Agent of such election prior to the first
Business Day following the date on which such Event of Default first occurs and (ii) pay the Extension Fee, on or before the close of business on the date on which such Event of Default first occurs, on all Notes then Outstanding. Upon the
Company’s failure to give such notice or to pay the Extension Fee when due, the Notes shall be subject to acceleration as provided in the first paragraph of this Section 5.02. On and after the 91st calendar day after such Event of Default
occurs, if such Event of Default is not cured or waived prior to such 91st calendar day, the Notes shall be subject to acceleration as provided in the first paragraph of this Section 5.02. If an Extension Fee is payable under this
Section 5.02, the Company shall deliver to the Trustee a certificate to that effect stating (i) the amount of such Extension Fee that is payable and (ii) the date on which such Extension Fee is payable. Unless and until a Responsible
Officer of the Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that the Extension Fee is not payable. If the Extension Fee has been paid by the Company directly to the Holders, the Company
shall deliver to the Trustee a certificate setting forth the particulars of such payment. 
  

Notwithstanding the foregoing paragraph, if an Event of Default (as defined therein) occurs under any series of the
Company’s debt securities (other than the Notes) issued subsequent to the Issue Date resulting from the Company’s failure to comply with obligations similar to those contained in Section 10.06 or the requirements of
Section 314(a)(1) of the Trust 

  
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Indenture Act, and such Event of Default is not subject to extension on terms similar to those set forth in the foregoing paragraph, then the Extension Right shall no longer apply and the Notes
shall be subject to acceleration as provided in the first paragraph of this Section 5.02. 
  

This Section 5.02, however, is subject to the conditions that if, at any time after the Accreted Principal Amount of
the Notes shall have been so declared due and payable, and before any judgment or decree for the payment of the monies due shall have been obtained or entered as hereinafter provided, the Company shall pay or shall deposit with the Trustee a sum
sufficient to pay installments of accrued and unpaid Interest upon all Notes and the Accreted Principal Amount of any and all Notes that shall have become due otherwise than by acceleration (with Interest on installments of accrued and unpaid
Interest (to the extent that payment of such Interest is enforceable under applicable law) and on such Accreted Principal Amount at the rate borne by the Notes during the period of such Default) and amounts due to the Trustee pursuant
Section 6.6 of the Base Indenture, and if (1) rescission would not conflict with any judgment or decree of a court of competent jurisdiction and (2) any and all Events of Defaults under this Supplemental Indenture with respect to such
Notes, other than the nonpayment of Accreted Principal Amount of and accrued and unpaid Interest on such Notes that shall have become due solely by such acceleration, shall have been cured or waived pursuant to Section 5.04, then and in every
such case the Holders of a majority in aggregate principal amount of the Outstanding Notes, by written notice to the Company and to the Trustee, may waive all Defaults or Events of Default with respect to the Notes and rescind and annul such
declaration and its consequences and such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured for every purpose of this Indenture; but no such waiver or rescission and annulment shall extend to
or shall affect any subsequent Default or Event of Default, or shall impair any right consequent thereon. 
  

SECTION 5.03 Unconditional Right of Holders to Receive Principal and Interest and to Convert. 

 
 Notwithstanding any other provision in this
Indenture, the Holder of any Note shall have the right, which is absolute and unconditional, to receive payment of the Accreted Principal Amount of and (subject to Section 3.10) Interest on such Note on the Maturity Date, and to convert such
Note in accordance with Article 12, and to institute suit for the enforcement of any such payment and right to convert, and such rights shall not be impaired without the consent of such Holder. 

 
 SECTION 5.04 Waiver of Past Defaults and
Rescission of Acceleration. 
  

With the consent of the Holders of not less than a majority in the aggregate Accreted Principal Amount of the Outstanding
Notes (including, without limitation, consents obtained in connection with a purchase of, or tender offer or exchange offer for, the Notes), any past Default hereunder and its consequences may be waived on behalf of the Holders of all of the Notes,
except a Default (A) in the payment of the Accreted Principal Amount of or Interest on any Note or in the delivery of amounts due upon conversion, or (B) in respect of a covenant or provision hereof which under Article 8 cannot be modified
or amended without the consent of the Holder of each Outstanding Note affected, and rescind any such acceleration with respect to the Notes and its consequences if (1) rescission would not conflict with any judgment or decree of a court


  
 36 









 
of competent jurisdiction and (2) all existing Events of Default, other than the nonpayment of Accreted Principal Amount of and Interest on the Notes or failure to deliver amounts due upon
conversion that have become due solely by such declaration of acceleration, have been cured or waived. 
  

Upon the waiver of any such Default, such Default shall cease to exist, and any Event of Default arising therefrom shall
be deemed to have been cured, for every purpose of the Indenture; but no such waiver shall extend to any subsequent or other Default or impair any right consequent thereon. 

 
 SECTION 5.05 Waiver of Stay, Usury or
Extension Laws. 
  
 The Company
covenants (to the extent that it may lawfully do so) that it shall not at any time insist upon, or plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, usury or extension law wherever enacted, now or at any time
hereafter in force, that may affect the covenants or the performance of the Indenture; and the Company (to the extent that it may lawfully do so) hereby expressly waives all benefit or advantage of any such law and covenants that it shall not
hinder, delay or impede by reason of such law the execution of any power herein granted to the Trustee, but shall suffer and permit the execution of every such power as though no such law had been enacted. 

 
 SECTION 5.06 Control by Holders.

  
 The Holders of a majority in
aggregate Accreted Principal Amount of the Outstanding Notes shall have the right to direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee,
provided that 
  
 (a) such direction shall not
be in conflict with any rule of law or with the Indenture; 
  
 (b) the Trustee may take any other action deemed proper by the Trustee which is not inconsistent with such direction; and 

 
 (c) the Trustee may refuse to follow any direction that
conflicts with law or the Indenture, or that the Trustee determines is unduly prejudicial to the rights of any other Holder or would involve the Trustee in personal liability, 

 
 provided further that, prior to taking any action
under the Indenture, the Trustee will be entitled to indemnification satisfactory to it in its sole discretion against all losses and expenses caused by taking or not taking such action. 
  
 SECTION 5.07 Collection of Indebtedness and Suits for Enforcement by Trustee. 

 
 The Company covenants that if: 

 
 (1) default is made in the payment of any
Interest on any Note when such Interest becomes due and payable and such default continues for a period of 30 days, or 

  
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 (2) default is made in the payment of the Accreted Principal Amount of (or
premium, if any, on) any Note at the Maturity thereof, 
  
 the Company will, upon demand of the Trustee, pay to it, for the benefit of the Holders of such Notes, the whole amount then due and payable on such Notes for Accreted Principal Amount and Interest, and,
to the extent that payment of such Interest shall be legally enforceable, Interest on any overdue Accreted Principal Amount and on any overdue Interest, at the rate borne by the Notes, and, in addition thereto, such further amount as shall be
sufficient to cover the costs and expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel. 

 
 If an Event of Default occurs and is
continuing, the Trustee may in its discretion proceed to protect and enforce its rights and the rights of the Holders by such appropriate judicial proceedings as the Trustee shall deem most effectual to protect and enforce any such rights, whether
for the specific enforcement of any covenant or agreement in the Indenture or in aid of the exercise of any power granted herein, or to enforce any other proper remedy. 

 
 SECTION 5.08 Trustee May File Proofs of
Claim. 
  
 In case of any
judicial proceeding relative to the Company (or any other obligor upon the Notes), its property or its creditors, the Trustee shall be entitled and empowered, by intervention in such proceeding or otherwise, to take any and all actions authorized
under the Trust Indenture Act in order to have claims of the Holders and the Trustee allowed in any such proceeding. In particular, the Trustee shall be authorized to collect and receive any moneys or other property payable or deliverable on any
such claims and to distribute the same; and any custodian, receiver, assignee, trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized by each Holder to make such payments to the Trustee and,
in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel,
and any other amounts due the Trustee under Section 6.6 of the Base Indenture. 
  

No provision of the Indenture shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on
behalf of any Holder any plan of reorganization, arrangement, adjustment or composition affecting the Notes or the rights of any Holder thereof or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding.

  
 SECTION 5.09 Trustee May Enforce
Claims Without Possession of Notes. 
  
 All rights of action and claims under the Indenture or the Notes may be prosecuted and enforced by the Trustee without the possession of any of the Notes or the production thereof in any proceeding
relating thereto, and any such proceeding instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall, after provision for the payment of the reasonable compensation, expenses,
disbursements and advances of the Trustee, its agents and counsel, be for the ratable benefit of the Holders of the Notes in respect of which such judgment has been recovered. 

  
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 SECTION 5.10 Application of Money Collected. 

 
 Any money collected by the Trustee pursuant
to this Article shall be applied in the following order, at the date or dates fixed by the Trustee and, in case of the distribution of such money on account of principal (or premium, if any) or Interest, upon presentation of the Notes and the
notation thereon of the payment if only partially paid and upon surrender thereof if fully paid: 
  

FIRST: To the payment of all amounts due the Trustee under Section 6.6 of the Base Indenture; and 

 
 SECOND: To the payment of the amounts then
due and unpaid for Accreted Principal Amount of and Interest on the Notes in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on
such Notes for Accreted Principal Amount and Interest, respectively. 
  
 SECTION 5.11 Limitation on Suits. 
  

No Holder of any Note shall have any right to institute any proceeding, judicial or otherwise, with respect to the
Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder, unless: 
  

(1) such Holder has previously given written notice to the Trustee of a continuing Event of Default; 

 
 (2) the Holders of not less than 25% in
aggregate Accreted Principal Amount of the Outstanding Notes shall have made written request to the Trustee to institute proceedings in respect of such Event of Default in its own name as Trustee hereunder; 

 
 (3) such Holder or Holders have offered to
the Trustee security or indemnity satisfactory to it against any costs, liability or expense; 
  

(4) the Trustee for 60 calendar days after its receipt of such notice, request and offer of security or indemnity has
failed to institute any such proceeding; and 
  
 (5) no direction that, in the opinion of the Trustee, is inconsistent with such written request has been given to the Trustee during such 60 calendar day period by the Holders of a majority in aggregate
Accreted Principal Amount of the Outstanding Notes; 
  
 it being understood and intended that no one or more Holders shall have any right in any manner whatever by virtue of, or by availing of, any provision of this Supplemental Indenture to affect, disturb or
prejudice the rights of any other Holders, or to obtain or to seek to obtain priority or preference over any other Holders or to enforce any right under the Indenture, except in the manner herein provided and for the equal and ratable benefit of all
the Holders. 

  
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 SECTION 5.12 Restoration of Rights and Remedies. 

 
 If the Trustee or any Holder has instituted
any proceeding to enforce any right or remedy under the Indenture and such proceeding has been discontinued or abandoned for any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any
determination in such proceeding, the Company, the Trustee and the Holders shall be restored severally and respectively to their former positions hereunder and thereafter all rights and remedies of the Trustee and the Holders shall continue as
though no such proceeding had been instituted. 
  

SECTION 5.13 Rights and Remedies Cumulative. 

 
 Except as otherwise provided with respect to
the replacement or payment of mutilated, destroyed, lost or stolen Notes in the last paragraph of Section 3.09, no right or remedy herein conferred upon or reserved to the Trustee or to the Holders is intended to be exclusive of any other right
or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of
any right or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or employment of any other appropriate right or remedy. 
  

SECTION 5.14 Delay or Omission Not Waiver. 

 
 No delay or omission of the Trustee or of
any Holder of any Note to exercise any right or remedy accruing upon any Event of Default shall impair any such right or remedy or constitute a waiver of any such Event of Default or an acquiescence therein. Every right and remedy given by this
Article or by law to the Trustee or to the Holders may be exercised from time to time, and as often as may be deemed expedient, by the Trustee or by the Holders, as the case may be. 
  
 SECTION 5.15 Undertaking for Costs. 

 
 In any suit for the enforcement of any right
or remedy under the Indenture, or in any suit against the Trustee for any action taken, suffered or omitted by it as Trustee, a court may require any party litigant in such suit to file an undertaking to pay the costs of such suit, and may assess
reasonable costs, including reasonable attorneys’ fees and expenses, against any such party litigant, in the manner and to the extent provided in the Trust Indenture Act; provided, that neither this Section 5.15 nor the Trust
Indenture Act shall be deemed to authorize any court to require such an undertaking or to make such an assessment in any suit instituted by the Company or in any suit for the enforcement of the right to convert any Note in accordance with Article
12. 

  
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 ARTICLE 6 
 [RESERVED.] 
  
 ARTICLE 7 
 CONSOLIDATION, MERGER,
CONVEYANCE, TRANSFER OR LEASE 
  
 SECTION 7.01 Company May Consolidate, Etc., Only on Certain Terms. 
  

The Company shall not consolidate with or merge with or into any other Person or convey, transfer or lease all or
substantially all of its properties and assets to any Person, unless: 
  
 (1) the resulting, surviving or transferee Person, if not the Company, is a corporation, partnership, limited liability company or other business entity organized and existing under the laws of the United
States of America, any State thereof or the District of Columbia, and such Person, if not the Company, expressly assumes by supplemental indenture all of the Company’s obligations under the Notes and the Indenture; 

 
 (2) immediately after giving effect to such
transaction, no Default has occurred and is continuing; and 
  
 (3) the Company has delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each stating that such consolidation, merger, conveyance, transfer or lease and, if a supplemental
indenture is required in connection with such transaction, such supplemental indenture comply with this Article and that all conditions precedent herein provided for relating to such transaction have been complied with. 

 
 SECTION 7.02 Successor Substituted.

  
 Upon any consolidation of the
Company with, or merger of the Company into, any other Person or any conveyance, transfer or lease of all or substantially all of the properties and assets of the Company in accordance with Section 7.01, the successor Person formed by such
consolidation or into which the Company is merged or to which such conveyance, transfer or lease is made shall succeed to, and be substituted for, and may exercise every right and power of, the Company under the Indenture with the same effect as if
such successor Person had been named as the Company herein, and thereafter, except in the case of a lease, the predecessor Person shall be relieved of all obligations and covenants under the Indenture and the Notes. 

 
 ARTICLE 8 

SUPPLEMENTAL INDENTURES 

 
 SECTION 8.01 Supplemental Indentures Without
Consent of Holders. 
  
 Without
the consent of any Holders, the Company, when authorized by a Board Resolution, and the Trustee, upon receipt of a Company Request, at any time and from time to time, may enter into one or more indentures supplemental hereto for any of the following
purposes: 
  
 (a) to (i) cure any ambiguity,
manifest error or defect or (ii) cure any omission or inconsistency, provided, in the case of clause (ii), the rights of the Holders are not adversely affected in any material respect; or 

  
 41 









 (b) to provide for the assumption by a successor corporation of the Company’s
obligations under the Supplemental Indenture; or 
  

(c) to add guarantees with respect to the Notes; or 

 
 (d) to secure the Notes; or 

 
 (e) to add to the covenants of the Company for the benefit of
the Holders or to surrender any right or power herein conferred upon the Company; or 
  
 (f) to provide for the conversion of Notes in accordance with the terms of this Supplemental Indenture; or 
  

(g) to make any changes to this Supplemental Indenture or the Notes that does not adversely affect the rights of any Holder in any
material respect; or 
  
 (h) to comply with the
requirements of the Trust Indenture Act or the rules and regulations of the Commission thereunder in order to effect or maintain the qualification of this Supplemental Indenture under the Trust Indenture Act, as contemplated by this Supplemental
Indenture or otherwise; or 
  
 (i) to evidence and
provide for the acceptance of appointment hereunder by a successor Trustee; or 
  
 (j) to provide for the issuance of Additional Notes in accordance with the terms and conditions of this Supplemental Indenture. 

 
 Upon a Company Request, accompanied by a
Board Resolution authorizing the execution of any such supplemental indenture, and subject to and upon receipt by the Trustee of the documents described in Section 9.3 of the Base Indenture, the Trustee shall (subject to the last sentence
Section 9.3 of the Base Indenture) join with the Company in the execution of any supplemental indenture authorized or permitted by the terms of this Supplemental Indenture and to make any further appropriate agreements and stipulations that may
be therein contained. 
  
 SECTION 8.02
Supplemental Indentures With Consent of Holders. 
  
 With the written consent of the Holders of not less than a majority in aggregate Accreted Principal Amount of the Outstanding Notes (including without limitation, consents obtained in connection with a
purchase of, or tender offer or exchange offer for Notes), by the Act of said Holders delivered to the Company and the Trustee, the Company, when authorized by a Board Resolution, and the Trustee may enter into an indenture or indentures
supplemental hereto for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Supplemental Indenture or of modifying in any manner the rights of the Holders under this Supplemental Indenture;
provided, however, that no such supplemental indenture shall, without the consent of the Holder of each Outstanding Note affected thereby: 
  

(a) reduce the percentage in aggregate Accreted Principal Amount of Notes the Holders of which must consent to an amendment; or


  
 42 









 (b) reduce the rate, or change the stated time for payment, of Interest on any Note or
reduce the amount, or extend the stated time for payment, of the Extension Fee; or 
  
 (c) reduce the Original Principal Amount or Accreted Principal Amount, or extend the Maturity Date, of any Note; or 
  

(d) make any change that adversely affects the conversion rights of any Note; or 
  
 (e) reduce the Fundamental Change Repurchase Price, Optional Put Repurchase Price or Redemption Price of any
Note or amend or modify in any manner adverse to the Holders of the Notes the Company’s obligations to make such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; or 

 
 (f) change the place or currency of payment of Accreted
Principal Amount, Interest, Optional Put Repurchase Price, Fundamental Change Repurchase Price, Redemption Price or the Extension Fee in respect of any Note; or 
  

(g) impair the right of any Holder to receive payment of Accreted Principal Amount of, and Interest on, such Holder’s Notes on or
after the due dates therefor or to institute suit for the enforcement of any payment on or with respect to such Holder’s Note; or 
  

(h) contractually subordinate the Notes in right of payment to any other Indebtedness of the Company; or 

 
 (i) make any change in the provisions of this Article 8 that
require each Holder’s consent or in the waiver provisions in Section 5.02 or Section 5.04. 
  

It shall not be necessary for the consent of Holders under this Section 8.02 to approve the particular form of any
proposed supplemental indenture, but it shall be sufficient if such consent shall approve the substance thereof. 
  

This Section 8.02 shall be subject to Section 9.3 of the Base Indenture. 

 
 SECTION 8.03 Notice of Supplemental
Indentures. 
  
 Promptly after
the execution by the Company and the Trustee of any supplemental indenture pursuant to the provisions of Section 8.02, the Company shall promptly give notice in the manner provided in Section 1.6 of the Base Indenture briefly setting forth
in general terms the substance of such supplemental indenture. Any failure of the Company to give such notice, or any defect therein, shall not in any way impair or affect the validity of any such supplemental indenture. 

  
 43 









 SECTION 8.04 Effect of Supplemental Indentures. 

 
 Upon the execution of any supplemental
indenture under this Article 8, this Supplemental Indenture shall be modified in accordance therewith, and such supplemental indenture shall form a part of this Supplemental Indenture for all purposes; and every Holder theretofore or thereafter
authenticated and delivered hereunder shall be bound thereby. 
  
 SECTION 8.05 Conformity with Trust Indenture Act. 
  

Every supplemental indenture executed pursuant to this Article 8 shall conform to the requirements of the Trust Indenture
Act. 
  
 ARTICLE 9 

HOLDERS LISTS AND BY TRUSTEE AND
COMPANY 
  
 SECTION 9.01
Company to Furnish Trustee Names and Addresses of Holders. 
  
 The Company will furnish or cause to be furnished to the Trustee 
  

(a) semi-annually, not more than 15 calendar days after each Regular Record Date, a list, in such form as the Trustee may reasonably
require, of the names and addresses of the Holders as of such Regular Record Date, and 
  
 (b) at such other times as the Trustee may request in writing, within 30 days after the receipt by the Company of any such request, a list of similar form and content as of a date not more than 15 days
prior to the time such list is furnished; 
  

excluding from any such list names and addresses received by the Trustee in its capacity as Registrar. 

 
 SECTION 9.02 Preservation of Information.

  
 (a) The Trustee shall preserve, in as current a
form as is reasonably practicable, the names and addresses of Holders contained in the most recent list furnished to the Trustee as provided in Section 9.01 and the names and addresses of Holders received by the Trustee in its capacity as
Registrar. The Trustee may dispose of any list furnished to it as provided in Section 9.01 upon receipt of a new list so furnished. 
  

(b) The rights of Holders to communicate with other Holders with respect to their rights under this Supplemental Indenture or under the
Notes, and the corresponding rights and duties of the Trustee, shall be as provided by the Trust Indenture Act. 
  

(c) Every Holder, by receiving and holding the same, agrees with the Company and the Trustee that neither the Company nor the Trustee nor
any agent of either of them shall be held accountable by reason of any disclosure of information as to names and addresses of Holders made pursuant to the Trust Indenture Act. 

  
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 ARTICLE 10 
 COVENANTS 
  
 SECTION 10.01 Payment of Principal and Interest. 
  

The Company covenants and agrees that it shall duly and punctually pay the Accreted Principal Amount of and Interest on
the Notes in accordance with the terms of the Notes and this Supplemental Indenture. The Company shall deposit or cause to be deposited with the Trustee or its nominee, no later than 1:00 p.m., New York City time, on the Maturity Date of the Notes
or no later than 1:00 p.m., New York City time, on the due date for any installment of Interest, all payments so due, which payments shall be in immediately available funds on the date of such Maturity Date or due date, as the case may be.

  
 SECTION 10.02 Maintenance of
Offices or Agencies. 
  
 The
Company shall maintain in an office or agency where the Notes may be surrendered for registration of transfer or exchange or for presentation for payment or for conversion or repurchase and where notices and demands to or upon the Company in respect
of the Notes and this Supplemental Indenture may be served. The Company shall give prompt written notice to the Trustee of the location, and any change in the location, of such office or agency not designated or appointed by the Trustee. If at any
time the Company shall fail to maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office.

  
 The Company may at any time and
from time to time vary or terminate the appointment of any such agent or appoint any additional agents for any or all of such purposes; provided, however, that until all of the Notes have been delivered to the Trustee for cancellation,
or moneys sufficient to pay the principal of and Interest on the Notes have been made available for payment and either paid or returned to the Company pursuant to the provisions of Section 10.05, the Company shall maintain an office or agency
where Notes may be presented or surrendered for payment and conversion, where Notes may be surrendered for registration of transfer or exchange and where notices and demands to or upon the Company in respect of the Notes and this Supplemental
Indenture may be served. The Company shall give prompt written notice to the Trustee, and notice to the Holders in accordance with Section 1.6 of the Base Indenture, of the appointment or termination of any such agents and of the location and
any change in the location of any such office or agency. 
  
 The Company hereby initially designates the Trustee as Paying Agent, Registrar, and Conversion Agent, and the Corporate Trust Office of the Trustee as the office or agency of the Company for each of the
aforesaid purposes. 
  
 Any rights
or immunities of the Trustee under the Indenture shall apply to the Trustee when acting under any or all of the aforementioned capacities. 

  
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 SECTION 10.03 Existence. 

 
 Subject to Section 7.01, the Company
shall do or cause to be done all things necessary to preserve and keep in full force and effect its corporate existence. 
  

SECTION 10.04 Annual Statement by Officers. 

 
 The Company shall deliver to the Trustee,
within 120 calendar days after the end of each fiscal year, an Officers’ Certificate as to the signing officers’ knowledge of the Company’s compliance with all conditions and covenants on its part contained in this Supplemental
Indenture. For purposes of this Section 10.04, such compliance shall be determined without regard to any grace period or requirement of notice provided under this Supplemental Indenture. 
  
 Any notice required to be given under this Section 10.04 shall be delivered to the Trustee
at its Corporate Trust Office. 
  

SECTION 10.05 Money for Note Payments to Be Held in Trust. 
  
 If the Company shall at any time act as its own Paying Agent, it will, on or before each due
date of the Accreted Principal Amount of or Interest on any of the Notes, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient to pay all amounts payable to the Trustee under Section 6.6 of the Base
Indenture and the Accreted Principal Amount or Interest so becoming due until such sums shall be paid to such Persons or otherwise disposed of as herein provided and will promptly notify the Trustee of its action or failure so to act. 

 
 Whenever the Company shall have one or more
Paying Agents, it will, prior to each due date of the Accreted Principal Amount of or Interest on any Notes, deposit with a Paying Agent a sum sufficient to pay such amount, such sum to be held as provided by the Trust Indenture Act, and (unless
such Paying Agent is the Trustee) the Company will promptly notify the Trustee of its action or failure so to act. 
  

The Company will cause each Paying Agent other than the Trustee to execute and deliver to the Trustee an instrument in
which such Paying Agent shall agree with the Trustee, subject to the provisions of this Section 10.05, that such Paying Agent will (i) comply with the provisions of the Trust Indenture Act applicable to it as a Paying Agent and
(ii) during the continuance of any default by the Company (or any other obligor upon the Notes) in the making of any payment in respect of the Notes, upon the written request of the Trustee, forthwith pay to the Trustee all sums held in trust
by such Paying Agent as such. 
  

The Company may at any time, for the purpose of obtaining the satisfaction and discharge of this Indenture or for any
other purpose, pay, or by Company Order direct any Paying Agent to pay, to the Trustee all sums held in trust by the Company or such Paying Agent, such sums to be held by the Trustee upon the same trusts as those upon which such sums were held by
the Company or such Paying Agent; and, upon such payment by any Paying Agent to the Trustee, such Paying Agent shall be released from all further liability with respect to such money. 

  
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 Any money deposited with the Trustee or any Paying Agent, or then held by
the Company, in trust for the payment of the principal of or Interest on any Note and remaining unclaimed for two years after such Accreted Principal Amount or Interest has become due and payable shall be paid to the Company on Company Request, or
(if then held by the Company) shall be discharged from such trust; and the Holder of such Note shall thereafter, as an unsecured general creditor, look only to the Company for payment thereof, and all liability of the Trustee or such Paying Agent
with respect to such trust money, and all liability of the Company as trustee thereof, shall thereupon cease; provided, however, that the Trustee or such Paying Agent, before being required to make any such repayment, may at the
expense of the Company cause to be published once, in a Press Release, notice that such money remains unclaimed and that, after a date specified therein, which shall not be less than 30 calendar days from the date of such publication, any unclaimed
balance of such money then remaining will be repaid to the Company. 
  
 SECTION 10.06 Reports by Company. 
  
 (a) The Company shall file any documents or reports that it is required to file with the Commission pursuant to Section 13 or 15(d) of the Exchange Act with the Trustee within 30 calendar days after
the same are required to be filed with the Commission. Documents filed by the Company with the Commission via the EDGAR system (or any successor thereto) will be deemed filed with the Trustee as of the time such documents are filed via EDGAR (or any
successor thereto). 
  
 (b) Delivery of such reports,
information and documents to the Trustee is for informational purposes only, and the Trustee’s receipt of such shall not constitute constructive notice of any information contained therein or determinable from information contained therein,
including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to conclusively rely exclusively on an Officers’ Certificate). Notwithstanding anything to the contrary in this Section 10.06,
the Company, to the extent permitted under the Trust Indenture Act, shall not be required to deliver to the Trustee or the Holders any material for which the Company has sought and received confidential treatment by the Commission. 

 
 SECTION 10.07 [Reserved] 

 
 SECTION 10.08 Tax Treatment of Notes.

  
 The Company agrees, and by
acceptance of a beneficial ownership interest in the Notes each Holder is deemed to have agreed, for United States federal income tax purposes, 
  

(a) to treat the Notes as indebtedness subject to United States Treasury Regulation Section 1.1275-4 (the “Contingent Payment
Debt Regulations”) and, for purposes of the Contingent Payment Debt Regulations, to treat cash and the fair market value of any Common Stock beneficially received by a Holder upon conversion of such Note as a contingent payment under
Treasury Regulation Section 1.1275-4(b); 
  
 (b)
to be bound by the Company’s application of the Contingent Payment Debt Regulations to the Notes, including the Company’s determination of the comparable yield and projected payment schedule, as defined in the Contingent Payment Debt
Regulations, with respect to the Notes. A Holder may obtain the issue price, issue date, comparable yield (which will be treated as the yield to 

  
 47 









 
maturity for United States federal income tax purposes) and projected payment schedule by submitting a written request to the Company at the following address: Hologic, Inc., 35 Crosby Drive,
Bedford, Massachusetts 01730, Attention: Investor Relations; 
  
 (c) that the comparable yield and the projected payment schedule are not determined for any purpose other than for the purpose of applying Treasury Regulation Section 1.1275-4(b) to the Notes, and
the comparable yield and the projected payment schedule do not constitute a projection or representation regarding the actual amounts payable on the Notes; 
  

(d) to use the projected payment schedule referred to in Section 10.08(b) above, as required by United States Treasury Regulations
Section 1.1275-4(b)(4)(iv), to determine its interest accruals and adjustments as provided by United States Treasury Regulation Section 1.1275-4(b); and 

 
 (e) the Company and each Holder shall not take any position
on a tax return inconsistent with (a), (b), (c) or (d), unless otherwise required by applicable law. 
  

ARTICLE 11 

REDEMPTION AND REPURCHASE OF NOTES 

 
 SECTION 11.01 Right to Redeem; Notice to
Trustee. 
  
 At any time on or
after December 19, 2016, the Company may redeem any or all of the Notes, except for the Notes that the Company is required to repurchase pursuant to Section 11.08 and Section 11.09, in cash at the Redemption Price (as defined below).

  
 The redemption price will equal
100% of the Accreted Principal Amount of the Notes being redeemed, plus accrued and unpaid Interest, if any, to, but not including, the Redemption Date (the “Redemption Price”). However, if the Redemption Date is after a Regular
Record Date and on or prior to the corresponding Interest Payment Date, the Company shall pay the full amount of accrued and unpaid Interest payable on such Interest Payment Date to the Holder of record at the close of business on the corresponding
Regular Record Date. 
  
 If the
Company elects to redeem Notes pursuant to this Section 11.01, it shall notify the Trustee at least 45 calendar days prior to the Redemption Date, as fixed by the Company (unless a shorter notice shall be satisfactory to the Trustee), of the
Redemption Date and the Accreted Principal Amount of Notes to be redeemed. 
  
 Notwithstanding the foregoing, the Company may not redeem any Notes if the Company has failed to pay any Interest due on the Notes and such failure to pay is continuing. 

 
 SECTION 11.02 Selection of Notes to Be
Redeemed. 
  
 If less than all
of the outstanding Notes are to be redeemed, the Trustee will select the Notes to be redeemed in Original Principal Amounts of $1,000 or multiples of $1,000 by lot, pro rata or by another method the Trustee considers reasonable. If a portion of a
Holder’s Notes is selected for redemption and such Holder converts a portion of its Notes, the converted portion will be deemed to be of the portion selected for redemption. Provisions of this Supplemental


  
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Indenture that apply to Notes called for redemption also apply to portions of Notes called for redemption. If any Note selected for partial redemption is converted in part before termination of
the conversion right with respect to the portion of the Note so selected, the converted portion of such Note shall be deemed to be taken from the portion selected for redemption. Notes which have been converted during a selection of Notes to be
redeemed shall be treated by the Trustee as Outstanding for the purpose of such selection. 
  
 SECTION 11.03 Notice of Redemption. 
  

Not more than 60 calendar days but not less than 30 calendar days prior to the Redemption Date, the Company shall give a
Notice of Redemption to all record Holders at their addresses set forth in the Securities Register of the Registrar. 
  

The notice shall identify the Notes to be redeemed and shall state: 

 
 (a) that the Holder has a right to convert the Notes called
for Redemption, and the Conversion Rate then in effect; 
  
 (b) the Redemption Date; 
  
 (c) the Redemption Price; 
  
 (d) the name and address of each Paying Agent and Conversion Agent; 
  

(e) that Notes called for redemption must be presented and surrendered to a Paying Agent to collect the Redemption Price; 

 
 (f) that Holders who wish to convert Notes must surrender
such Notes for conversion no later than 5:00 p.m., New York City time, on the Scheduled Trading Day immediately preceding the Redemption Date and must satisfy the other requirements set forth in Article 12 (which shall be specified in such notice);

  
 (g) that, unless the Company defaults in making
the payment of the Redemption Price, Interest on Notes called for redemption shall cease accruing on and after the Redemption Date and subject to the provisions of Sections 11.01 and 11.04, the only remaining right of the Holder shall be to receive
payment of the Redemption Price upon presentation and surrender to a Paying Agent of the Notes; and 
  
 (h) if any Note is being redeemed in part, the portion of the Accreted Principal Amount of such Note to be redeemed and that, after the Redemption Date, upon presentation and surrender of such Note, new
Notes in an aggregate Accreted Principal Amount equal to the unredeemed portion thereof will be issued. 
  

If any of the Notes to be redeemed is in the form of a Global Security, then the Company shall modify such notice to the
extent necessary to accord with the procedures of the Depositary applicable to redemptions. At the Company’s written request, the Trustee shall give the notice of redemption in the Company’s name and at the Company’s expense.


  
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 SECTION 11.04 Effect of Notice of Redemption. 

 
 Once notice of redemption is mailed, Notes
called for redemption become due and payable on the Redemption Date and at the Redemption Price stated in the notice except for Notes that are converted in accordance with the terms of this Supplemental Indenture. Upon presentation and surrender to
a Paying Agent, Notes called for redemption shall be paid in cash at the Redemption Price stated in the notice and from and after the Redemption Date such Notes shall cease to bear Interest and the rights of the Holders therein shall terminate
(other than the right to receive the Redemption Price). 
  
 SECTION 11.05 Deposit of Redemption Price. 
  

Prior to 1:00 p.m., New York City time, on the Redemption Date, the Company shall deposit with a Paying Agent (or, if the
Company acts as Paying Agent, shall segregate and hold in trust) an amount of money (in immediately available funds if deposited on such Redemption Date) sufficient to pay the Redemption Price of all Notes to be redeemed on that date, other than
Notes or portions thereof called for redemption on that date which have been delivered by the Company to the Trustee for cancellation or have been converted. The Paying Agent shall as promptly as practicable return to the Company any money not
required for that purpose or, if such money is then held by the Company in trust and is not required for such purpose, it shall be discharged from the trust. 
  

If the Paying Agent holds on a Redemption Date cash sufficient to pay the Redemption Price payable on that date, then on
and after such Redemption Date, such Notes (or portions thereof, as the case may be) shall cease to be outstanding, the Accreted Principal Amount shall cease to accrete and Interest (if any) on them shall cease to accrue; provided that if
such Notes are to be redeemed, notice of such redemption has been duly given pursuant to this Supplemental Indenture or provision therefor satisfactory to the Trustee has been made. 
  
 SECTION 11.06 Notes Redeemed in Part. 

 
 Upon presentation and surrender of a Note
that is redeemed in part, the Company shall execute and, upon receipt of a Company Order, the Trustee shall authenticate and deliver to the Holder, without charge, new Notes of authorized denominations as requested by such Holder in aggregate
Accreted Principal Amount equal to the unredeemed portion of the Note surrendered. 
  
 SECTION 11.07 No Redemption of Notes Upon Occurrence of Acceleration. 
  

Notwithstanding anything herein to the contrary, the Company will not redeem any Notes on any date if the Accreted
Principal Amount of the Notes has been accelerated, and such acceleration has not been rescinded on or prior to the Redemption Date (except in the case of an acceleration resulting from a default by the Company in the payment of the Redemption Price
with respect to such Notes). 

  
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 SECTION 11.08 Repurchase of Notes at the Option of Holders. 

 

	 	(a)	Optional Put (i) On December 15, 2016, December 15, 2020, December 15, 2025, December 13, 2030 and December 14, 2035
(each, an “Optional Put Repurchase Date”), each Holder shall have the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s Notes or any portion of the Original Principal Amount thereof
that is equal to $1,000 or an integral multiple of $1,000, for cash at a repurchase price equal to 100% of the Accreted Principal Amount thereof, together with accrued and unpaid Interest thereon to, but excluding, such Optional Put Repurchase Date
(the “Optional Put Repurchase Price”) (subject to satisfaction by or on behalf of the Holder of the requirements set forth in Section 11.08(a)(iii)), unless such Optional Put Repurchase Date falls after a Regular Record Date
and on or prior to the corresponding Interest Payment Date, in which case the Company shall pay the full amount of accrued and unpaid Interest payable on such Interest Payment Date to the Holder of record at the close of business on the
corresponding Regular Record Date. 

  
 (ii) No later than 20 Business Days prior to each Optional Put Repurchase Date, the Company shall give notice of the repurchase right under Section 11.08(a)(i) (an “Optional Put Repurchase
Offer”) to all record Holders at their addresses set forth in the Securities Register of the Registrar (and to beneficial owners as required by applicable law). The notice shall include a form of notice to be completed by the Holder and
returned to the Company in the event that the Holder elects to exercise such right to such repurchase (the “Optional Put Repurchase Notice”) and shall briefly state, as applicable: 

 
 (A) the date by which the Optional Put
Repurchase Notice must be delivered to the Paying Agent in order for a Holder to exercise the repurchase right; 
  

(B) the Optional Put Repurchase Date; 

 
 (C) the Optional Put Repurchase Price;

  
 (D) the name and address of the
Paying Agent and the Conversion Agent; 
  
 (E) the Conversion Rate; 
  
 (F) the conversion rights, if any, of the Notes; 
  

(G) that the Notes as to which an Optional Put Repurchase Notice has been given may be converted if they are otherwise
convertible pursuant to Article 12 only if the Optional Put Repurchase Notice has been withdrawn in accordance with the terms of this Supplemental Indenture; 
  

(H) that the Notes must be surrendered to the Paying Agent to collect payment; 

  
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 (I) that the Optional Put Repurchase Price for any Note as to which an
Optional Put Repurchase Notice has been duly given and not withdrawn will be paid promptly following the later of the Optional Put Repurchase Date and the time of surrender of such Note; 
  
 (J) the procedures the Holder must follow to exercise its put right under this
Section 11.08(a); 
  
 (K) the
procedures for withdrawing an Optional Put Repurchase Notice; 
  
 (L) that, unless the Company defaults in making payment of such Optional Put Repurchase Price, Interest on Notes surrendered for repurchase by the Company will cease to accrue on and after the Optional
Put Repurchase Date; and 
  
 (M)
the CUSIP number(s) of the Notes. 
  

At the Company’s request, the Trustee shall give the Optional Put Repurchase Offer Notice in the Company’s name
and at the Company’s expense; provided, however, that the Company makes such request at least three Business Days (unless a shorter period shall be satisfactory to the Trustee) prior to the date by which such Optional Put Repurchase
Offer Notice must be given to the Holder in accordance with this Section 11.08(a)(ii); provided, further, that the text of the Optional Put Repurchase Offer Notice shall be prepared by the Company. 

 
 (iii) A Holder may exercise its right
specified in Section 11.08(a)(i) upon delivery of a properly completed Optional Put Repurchase Notice to the Paying Agent at any time during the period beginning at 9:00 a.m., New York City time, on the date that is 20 Business Days immediately
preceding the relevant Optional Put Repurchase Date until 5:00 p.m., New York City time, on the Business Day immediately preceding such Optional Put Repurchase Date, stating: 

 
 (A) if certificated, the certificate
numbers of Notes to be delivered for repurchase; 
  
 (B) the portion of the Original Principal Amount of Notes to be repurchased, which portion must be $1,000 or an integral multiple of $1,000 thereof; and 

 
 (C) that the Notes shall be repurchased by
the Company pursuant to the applicable provisions of the Notes and this Supplemental Indenture. 
  

The book-entry transfer or delivery of such Note to the Paying Agent with, or at any time after delivery of, the Optional
Put Repurchase Notice (together with all necessary endorsements) at the offices of the Paying Agent shall be a condition to the receipt by the Holder of the Optional Put Repurchase Price therefor; provided, however, that such Optional Put
Repurchase Price shall be so paid pursuant to this Section 11.08(a) only if the Note so delivered to the Paying Agent shall conform in all respects to the description thereof in the related Optional Put Repurchase Notice. 

  
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 The Company shall repurchase from the Holder thereof, pursuant to this
Section 11.08(a), a portion of a Note, so long as the Original Principal Amount of such portion is $1,000 Original Principal Amount or an integral multiple of $1,000 Original Principal Amount. Provisions of this Supplemental Indenture that
apply to the repurchase of all of a Note also apply to the repurchase of such portion of such Note. 
  

The Paying Agent shall promptly notify the Company of the receipt by it of any Optional Put Repurchase Notice or written
notice of withdrawal thereof. 
  
 (b) Effect of
Optional Put Repurchase Notice. Upon receipt by the Paying Agent of the Optional Put Repurchase Notice specified in Section 11.08(a)(iii), the Holder of the Note in respect of which such Optional Put Repurchase Notice was given shall
(unless such Optional Put Repurchase Notice is withdrawn as specified in the following paragraph) thereafter be entitled to receive solely the Optional Put Repurchase Price with respect to such Note. Such Optional Put Repurchase Price shall be paid
to such Holder, subject to receipt of cash by the Paying Agent from the Company, on the later of (1) the Optional Put Repurchase Date with respect to such Note (provided the conditions in Section 11.08(a)(iii) have been satisfied) and
(2) the time of book-entry transfer or delivery of such Note to the Paying Agent by the Holder thereof in the manner required by Section 11.08(a)(iii). Notes in respect of which an Optional Put Repurchase Notice has been given by the
Holder thereof may not be converted pursuant to Article 12 on or after the date of the delivery of such Optional Put Repurchase Notice unless such Optional Put Repurchase Notice has first been validly withdrawn as specified in the following
paragraph. 
  
 An Optional Put
Repurchase Notice may be withdrawn by means of a written notice of withdrawal delivered to the office of the Paying Agent in accordance with the Optional Put Repurchase Notice at any time prior to 5:00 p.m., New York City time, on the Business Day
immediately preceding the Optional Put Repurchase Date, specifying: 
  
 (i) the Original Principal Amount of such Note with respect to which such notice of withdrawal is being submitted; 
  

(ii) if certificated Notes have been issued, the certificate numbers of the withdrawn Notes; and 

 
 (iii) the Original Principal Amount, if any,
of such Note which remains subject to the Optional Put Repurchase Notice, which portion must be in Original Principal amounts of $1,000 or an integral multiple of $1,000. 

 
 provided, however, that with respect to Global
Notes, the notice must comply with the Applicable Procedures. 
  
 (c) Deposit of Optional Put Repurchase Price. Prior to 1:00 p.m., New York City time, on the applicable Optional Put Repurchase Date, the Company shall deposit with the Paying Agent (or if the
Company or a Subsidiary or an Affiliate of any of them is acting as the Paying Agent, shall 

  
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segregate and hold in trust as provided in Section 10.05) an amount of cash (in immediately available funds if deposited on such Business Day) sufficient to pay the aggregate Optional Put
Repurchase Price of all the Notes or portions thereof which are to be repurchased on such Optional Put Repurchase Date. 
  

If the Paying Agent (other than the Company or an Affiliate of the Company) holds, in accordance with the terms hereof, at
1:00 p.m., New York City time, on the applicable Optional Put Repurchase Date, cash sufficient to pay the Optional Put Repurchase Price of any Notes for which an Optional Put Repurchase Notice has been tendered and not withdrawn pursuant to
Section 11.08(b), then, on and after such Optional Put Repurchase Date, such Notes will cease to be outstanding, the Accreted Principal Amount shall cease to accrete and Interest, if any, on such Notes will cease to accrue, whether or not such
Notes are delivered to the Paying Agent, and the rights of the Holders in respect thereof shall terminate (other than the right to receive the Optional Put Repurchase Price upon delivery of such Notes, together with any necessary endorsement) and
the repurchased Notes shall be cancelled. 
  
 (d)
Notes Repurchased in Part. Any Certificated Note which is to be repurchased only in part shall be surrendered at the office of the Paying Agent (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of
transfer in form satisfactory to the Company and the Trustee duly executed by, the Holder thereof or such Holder’s attorney duly authorized in writing) and the Company shall execute and upon receipt of a Company Order the Trustee shall
authenticate and deliver to the Holder of such Note, without charge, new Notes, of any authorized denomination as requested by such Holder in aggregate Accreted Principal Amount equal to, and in exchange for, the portion of the Accreted Principal
Amount of the Note so surrendered which is not repurchased. 
  
 (e) Covenant to Comply with Securities Laws upon Repurchase of Notes. In connection with any repurchase of the Notes pursuant to this Section 11.08, the Company shall: 

 
 (i) comply with the provisions of Rule
13e-4, Rule 14e-1 (or any successor provision) and any other tender offer rules under the Exchange Act that may then be applicable; and 
  

(ii) otherwise comply with all federal and state securities laws. 

 
 To the extent that the provisions of any
securities laws or regulations conflict with the provisions of this Section 11.08, the Company’s compliance with such laws and regulations shall not in and of itself cause a breach of its obligations under this Section 11.08.

  
 (f) Repayment to the Company. The Paying
Agent shall return to the Company any cash that remains unclaimed for two years, together with Interest, if any, thereon, held by it for the payment of the Optional Put Repurchase Price; provided, however, to the extent that the aggregate
amount of cash deposited by the Company pursuant to Section 11.08(c) exceeds the aggregate Optional Put Repurchase Price of the Notes or portions thereof which the Company is obligated to repurchase on the Optional Put Repurchase Date, then,
promptly after the Optional Put Repurchase Date, the Paying Agent shall return any such excess to the Company. 

  
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 (g) No Repurchase Upon Acceleration. Notwithstanding anything herein to the contrary,
there shall be no purchase of any Notes pursuant to this Section 11.08 if the Accreted Principal Amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to the Optional Put Repurchase Date (except in
the case of an Event of Default resulting from a default by the Company in the payment of the Optional Put Repurchase Price with respect to such Notes). 
  

SECTION 11.09 Right to Require Repurchase Upon a Fundamental Change. 

 
 (a) If a Fundamental Change occurs at any time, then each
Holder shall have the right, at such Holder’s option, to require the Company to repurchase all of such Holder’s Notes or any portion of the Original Principal Amount thereof that is equal to $1,000 or an integral multiple of $1,000, for
cash on the date (the “Fundamental Change Repurchase Date”) specified by the Company that is not less than 20 calendar days and not more than 35 calendar days after the date of the Fundamental Change Repurchase Right Notice at a
repurchase price equal to 100% of the Accreted Principal Amount thereof, together with accrued and unpaid Interest thereon to, but excluding, the Fundamental Change Repurchase Date (the “Fundamental Change Repurchase Price”), unless
such Fundamental Change Repurchase Date falls after a Regular Record Date and on or prior to the corresponding Interest Payment Date, in which case the Company shall pay the full amount of accrued and unpaid Interest payable on such Interest Payment
Date to the Holder of record at the close of business on the corresponding Regular Record Date. 
  

However, notwithstanding the foregoing, Holders shall not have the right to require the Company to repurchase any Notes
under this Section 11.09 based on a Fundamental Change described in clause (1) or (2) of the definition thereof (and the Company shall not be required to deliver the Fundamental Change Repurchase Right Notice incidental thereto) if at
least 90% of the consideration paid for the Common Stock (excluding cash payments for fractional shares and cash payments made pursuant to dissenters’ appraisal rights and cash dividends) in a merger or consolidation or such other transaction
otherwise constituting a Fundamental Change described in clause (1) or (2) of the definition thereof consists of shares of Common Stock or American Depositary Receipts in respect of shares of Common Stock traded on any of the New York
Stock Exchange, the American Stock Exchange, the NASDAQ Global Market or the NASDAQ Global Select Market (or any of their respective successors) (or that will be so traded or quoted immediately following the completion of such merger or
consolidation or such other transaction) and, as a result of the completion of such merger or consolidation or such other transaction, the Notes become convertible into shares of such Common Stock or such American Depositary Receipts pursuant to
Section 12.10 (or cash or a combination of cash and shares of such Common Stock or such American Depositary Receipts pursuant to Section 12.10, if the Company so elects or has so elected). 

 
 Repurchases of Notes under this
Section 11.09 shall be made, at the option of the Holder thereof, upon: 
  
 (i) if the Notes are held in certificated form, delivery to the Trustee (or other Paying Agent appointed by the Company) by a Holder of a duly completed notice (the “Fundamental Change Repurchase
Notice”) in the form set forth on the reverse of the Note or, if the Notes are held in global form, a notice that complies with the Applicable Procedures, prior to the close of business on the Business Day immediately preceding the
Fundamental Change Repurchase Date; and 

  
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 (ii) delivery or book-entry transfer of the Notes to the Trustee (or other
Paying Agent appointed by the Company) prior to the close of business on the Business Day immediately preceding the Fundamental Change Repurchase Date (together with all necessary endorsements) at the Corporate Trust Office of the Trustee (or other
Paying Agent appointed by the Company), such delivery being a condition to receipt by the Holder of the Fundamental Change Repurchase Price therefor; provided that such Fundamental Change Repurchase Price shall be so paid pursuant to this
Section 11.09 only if the Note so delivered to the Trustee (or other Paying Agent appointed by the Company) shall conform in all respects to the description thereof in the related Fundamental Change Repurchase Notice. 

 
 The Fundamental Change Repurchase Notice
shall state: 
  
 (A) if
certificated, the certificate numbers of Notes to be delivered for repurchase; 
  
 (B) the portion of the Original Principal Amount of Notes to be repurchased, which must be $1,000 or an integral multiple thereof; and 

 
 (C) that the Notes are to be repurchased by
the Company pursuant to the applicable provisions of the Notes and this Supplemental Indenture. 
  

Any purchase by the Company contemplated pursuant to the provisions of this Section 11.09 shall be consummated by the
delivery of the consideration to be received by the Holder promptly following the later of the Fundamental Change Repurchase Date and the time of the book-entry transfer or delivery of the Note. 

 
 The Trustee (or other Paying Agent appointed
by the Company) shall promptly notify the Company of the receipt by it of any Fundamental Change Repurchase Notice or written notice of withdrawal thereof in accordance with the provisions of subsection (c) of this Section 11.09.

  
 Any Note that is to be
repurchased only in part shall be surrendered to the Trustee (with, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form satisfactory to the Company and the Trustee duly executed by, the Holder
thereof or his attorney duly authorized in writing), and the Company shall execute, and, upon receipt of a Company Order, the Trustee shall authenticate and make available for delivery to the Holder of such Note without service charge, a new Note or
Notes, containing identical terms and conditions, each in an authorized denomination in aggregate principal amount equal to and in exchange for the unrepurchased portion of the principal of the Note so surrendered. 

 
 (b) After the occurrence of a Fundamental Change, but on or
before the 10th calendar day after the Effective Date of such Fundamental Change, the Company shall provide to all Holders of record of the Notes and the Trustee and Paying Agent a notice (the “Fundamental Change Repurchase Right
Notice”) on the occurrence of such Fundamental Change and of the resulting repurchase right, if any, at the option of the Holders arising as a result thereof. 

  
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 Each Fundamental Change Repurchase Right Notice shall specify (if
applicable): 
  
 (i) the events
causing the Fundamental Change; 
  

(ii) the date of the Fundamental Change; 

 
 (iii) the last date on which a Holder may
exercise the repurchase right arising as a result of a Fundamental Change, if applicable; 
  

(iv) the Fundamental Change Repurchase Price, if applicable; 
  
 (v) the Fundamental Change Repurchase Date, if applicable; 

 
 (vi) the name and address of the Paying
Agent and the Conversion Agent, if applicable; 
  
 (vii) the applicable Conversion Rate and any adjustments to the applicable Conversion Rate; 
  

(viii) that the Notes with respect to which a Fundamental Change Repurchase Notice has been delivered by a Holder may be
converted only if the Holder withdraws the Fundamental Change Repurchase Notice in accordance with the terms of this Supplemental Indenture; and 
  

(ix) the procedures that Holders must follow to require the Company to repurchase their Notes. 

 
 No failure of the Company to give the
foregoing notices and no defect therein shall limit the Holders’ repurchase rights or affect the validity of the proceedings for the repurchase of the Notes pursuant to this Section 11.09. 

 
 (c) A Fundamental Change Repurchase Notice may be withdrawn
by means of a written notice of withdrawal delivered to the Paying Agent in accordance with the Fundamental Change Repurchase Right Notice at any time prior to the close of business on the Business Day prior to the Fundamental Change Repurchase
Date, specifying: 
  
 (i) the
Original Principal Amount of the Notes with respect to which such notice of withdrawal is being submitted; 
  

(ii) if certificated Notes have been issued, the certificate numbers of the withdrawn Notes; and 

 
 (iii) the Original Principal Amount, if any,
of such Note that remains subject to the original Fundamental Change Repurchase Notice, which portion must be in Original Principal Amounts of $1,000 or an integral multiple of $1,000; 

  
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 provided, however, that if the Notes are not in certificated form, the notice
must comply with the Applicable Procedures. 
  
 (d)
In connection with any repurchase of the Notes pursuant to this Section 11.09, the Company shall 
  

(i) comply with the provisions of Rule 13e-4, Rule 14e-1 (or any successor provision) and any other tender offer rules
under the Exchange Act that may then be applicable; and 
  
 (ii) otherwise comply with all applicable federal and state securities laws. 
  

To the extent that the provisions of any securities laws or regulations conflict with the provisions of this
Section 11.09, the Company’s compliance with such laws and regulations shall not in and of itself cause a breach of its obligations under this Section 11.09. 

 
 (e) On or prior to 1:00 p.m., New York City time, on the
Fundamental Change Repurchase Date, the Company shall deposit with the Trustee (or other Paying Agent appointed by the Company or if the Company is acting as its own Paying Agent, set aside, segregate and hold in trust as provided in
Section 10.05) an amount of money sufficient to repurchase all of the Notes to be repurchased on such date at the Fundamental Change Repurchase Price. Subject to receipt of funds and/or Notes by the Trustee (or other Paying Agent appointed by
the Company) from the Company or the Holders, as applicable, payment for Notes surrendered for repurchase (and not withdrawn) prior to the close of business on the Business Day prior to the Fundamental Change Repurchase Date shall be made promptly
after the later of (x) the Fundamental Change Repurchase Date with respect to such Note (provided the Holder has satisfied the conditions to the payment of the Fundamental Change Repurchase Price in this Section 11.09), and
(y) the time of book-entry transfer or the delivery of such Note to the Trustee (or other Paying Agent appointed by the Company) by the Holder thereof in the manner required by this Section 11.09. The Trustee shall, promptly after such
payment and upon written demand by the Company, return to the Company any funds in excess of the Fundamental Change Repurchase Price. 
  

(f) Subject to a Holder’s right to receive Interest on the related Interest Payment Date where the Fundamental Repurchase Date falls
between a Regular Record Date and the Interest Payment Date to which it relates, if the Trustee (or other Paying Agent appointed by the Company) holds money sufficient to repurchase on the Fundamental Change Repurchase Date all the Notes or portions
thereof that are to be purchased as of the Business Day following the Fundamental Change Repurchase Date, then on and after the Fundamental Change Repurchase Date (i) such Notes shall cease to be outstanding, (ii) the Accreted Principal
Amount shall cease to accrete, (iii) Interest shall cease to accrue on such Notes, and (iv) all other rights of the Holders of such Notes shall terminate, whether or not book-entry transfer of the Notes has been made or the Notes have been
delivered to the Trustee or Paying Agent, other than the right to receive the Fundamental Change Repurchase Price upon delivery of the Notes. 

  
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 ARTICLE 12 
 CONVERSION OF NOTES 
  

SECTION 12.01 Conversion Privilege and Conversion Rate. 
  
 (a) Subject to the conditions described in clauses (i), (ii), (iii) and (iv) below, and upon
compliance with the provisions of this Article 12, a Holder shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000 in Original Principal Amount or an integral multiple thereof) of
any Notes at any time prior to the close of business on the Scheduled Trading Day immediately preceding September 15, 2037, into shares of Common Stock (or, at the election of the Company, cash or a combination of cash and shares of Common
Stock as described herein) at a rate of 43.4216 shares of Common Stock (subject to adjustment by the Company as provided in Sections 12.01(e) and 12.04 hereof) per $1,000 in Original Principal Amount of the Notes (the “Conversion
Rate”) under the circumstances and during the periods set forth below. On and after September 15, 2037 regardless of the conditions described in clauses (i), (ii), (iii) and (iv) below, and upon compliance with the provisions
of this Article 12, a Holder shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000 in Original Principal Amount or an integral multiple thereof) of any Notes at the applicable
Conversion Rate at any time prior to the close of business on the second Scheduled Trading Day immediately preceding the Maturity Date. 
  

(i) The Notes shall be convertible prior to September 15, 2037, during the five Business Day period after any five
consecutive Trading Day period (as used in this Section 12.01(a)(i), the “Measurement Period”) in which the Trading Price per $1,000 in Original Principal Amount of the Notes for each Trading Day of such Measurement Period was
less than 98% of the product of the Last Reported Sale Price of the Common Stock on such Trading Day and the applicable Conversion Rate in effect on such Trading Day, as determined by the Trustee and subject to compliance with the procedures and
conditions described below concerning the Trustee’s obligation to make such determination (the “Trading Price Condition”). If a Holder provides the Company with reasonable evidence that the Trading Price per $1,000 in Original
Principal Amount of the Notes would be less than 98% of the product of (a) the then-applicable Conversion Rate of the Notes and (b) the Last Reported Sale Price at such time, then the Company shall instruct in writing the Trustee to
determine the Trading Price of the Notes beginning on the next Trading Day and on each successive Trading Day until the date on which the Trading Price per $1,000 in Original Principal Amount of the Notes is greater than or equal to 98% of the
product of (a) the then-applicable Conversion Rate of the Notes and (b) the Last Reported Sale Price (as provided to the Trustee by the Company on each such date). If the Trading Price Condition has been met in accordance with the
foregoing, the Company shall so notify the Holders of the Notes and the Trustee. If, at any time after the Trading Price Condition has been met in accordance with the foregoing, the Trading Price per $1,000 in Original Principal Amount of the Notes
is greater than 98% of the product of (a) the then-applicable Conversion Rate of the Notes and (b) the Last Reported Sale Price on such date, the Company shall so notify the Holders of the Notes and the Trustee, and the Trustee shall have
no further obligation to determine the Trading Price of the Notes unless requested by the Company to do so again in writing pursuant to 

  
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this Section 12.01(a)(i). Furthermore, if the Company does not, when obligated to do so pursuant to this clause (i), instruct the Trustee to determine the Trading Price of the Notes, or if
the Company so instructs the Trustee, but the Trustee does not make such determination, then the Trading Price per $1,000 in Original Principal Amount of the Notes shall be deemed to be less than 98% of the product of (a) the then-applicable
Conversion Rate of the Notes and (b) the Last Reported Sale Price on such date. 
  

(ii) The Notes shall be convertible prior to September 15, 2037, during any calendar quarter after the calendar
quarter ending December 31, 2010 (and only during such calendar quarter), if the Last Reported Sale Price of the Common Stock for 20 or more Trading Days in a period of 30 consecutive Trading Days ending on the last Trading Day of the
immediately preceding calendar quarter exceeds 130% of the applicable Conversion Price in effect on the last Trading Day of the immediately preceding calendar quarter. For each calendar quarter, the Company, or at the written request of the Company,
the Conversion Agent, will determine if the Notes are convertible as the result of the satisfaction of the condition in this Section 12.01(a)(ii) in the preceding calendar quarter and the Company will promptly notify the Holders and the Trustee
if this condition was satisfied. 
  

(iii) In the event the Company calls the Notes for redemption pursuant to Section 11.01, the Notes shall be
convertible pursuant to subsection (f) of this Section. 
  
 (iv) The Notes shall be convertible prior to September 15, 2037, as provided in subsections (b), (c) and (d) of this Section 12.01. 

 
 (b) In the event that the Company elects to: 

 
 (i) distribute to all or substantially all
holders of Common Stock any rights or warrants entitling them, for a period of not more than 60 calendar days after the record date for such distribution, to subscribe for or purchase Common Stock at a price per share less than the Last Reported
Sale Price of the Common Stock for the Trading Day immediately preceding the declaration date of such distribution; or 
  

(ii) distribute to all or substantially all holders of Common Stock assets (including cash) or debt securities of the
Company or certain rights to purchase the Company’s securities, which distribution has a per share value (as determined by the Board of Directors) exceeding 10% of the Last Reported Sale Price of the Common Stock on the Trading Day immediately
preceding the date of declaration of such distribution, 
  
 the Company shall notify Holders and the Trustee in writing with respect to any distribution referred to in either clause (i) or clause (ii) above and of the resulting conversion right no later
than the 35th Scheduled Trading Day prior to the Ex-Date for such distribution. Once the Company has given such notice, Holders may surrender the Notes for conversion at any time until the earlier of 5:00 p.m., New York City time, on the Business
Day immediately preceding the Ex-Date for such distribution or the date the Company announces that such distribution will not take place. A Holder may not exercise this right if such Holder is permitted to participate (as a result of holding the
Notes, and at the same time as holders of the Common Stock participate) 

  
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in any distribution referred to in clause (i) or clause (ii) above as if such Holder held a number of shares of Common Stock equal to the then-applicable Conversion Rate, multiplied by
the principal amount (expressed in thousands) of Notes held by such Holder, without having to convert its Notes. 
  

(c) If the Company is a party to a combination, merger, recapitalization, reclassification, binding-share exchange or other similar
transaction or sale or conveyance of all or substantially all of its properties and assets, in each case pursuant to which the Common Stock would be converted into cash, securities and/or other property and that does not also constitute a
Fundamental Change, then the Holders shall have the right to convert Notes at any time beginning on the effective date of such transaction and ending on the 30th Scheduled Trading Day following the effective date of such transaction. The Company
shall notify Holders and the Trustee in writing at least 10 Scheduled Trading Days prior to the anticipated effective date of any such transaction. The Board of Directors shall determine the anticipated effective date of the transaction, and such
determination shall be conclusive and binding on the Holders. 
  
 (d) If the Company is a party to any transaction or event described in the definition of Fundamental Change, a Holder may surrender Notes for conversion at any time, after the Company gives the notice
referred to in the last sentence of this Section 12.01(d), from the effective date of such event until (i) the Fundamental Change Repurchase Date corresponding to such events or (ii) if there is no such Fundamental Change Repurchase
Date, 30 Scheduled Trading Days following the effective date of such transaction or event. The Company shall notify in writing, in the manner provided for in Section 1.6 of the Base Indenture, each of the Holders and the Trustee of the
Fundamental Change on or before the date such event occurs or becomes effective or, if later, within 2 Business Days after the date the Company becomes aware of such occurrence or effectiveness. 

 
 (e) If a Holder elects to convert Notes in connection with a
Make-Whole Fundamental Change, the Conversion Rate applicable to each $1,000 in Original Principal Amount of Notes so converted shall be increased by an additional number of shares of Common Stock (the “Additional Shares”) as
described below; provided, however that no increase shall be made in the case of a transaction or event constituting a Fundamental Change described in clauses (1) or (2) of such definition where 90% or more of the
consideration for the Common Stock (excluding cash payments for fractional shares and cash payments made pursuant to dissenters’ appraisal rights) in such transaction consists of shares of Common Stock or American Depositary Receipts in respect
of shares of Common Stock traded on any of the New York Stock Exchange, the American Stock Exchange, the NASDAQ Global Market or the NASDAQ Global Select Market (or any of their respective successors) (or that will be so traded or quoted immediately
following the transaction) and as a result of such transaction or transactions the Notes become convertible (to the extent otherwise convertible into shares of Common Stock) into cash and, if applicable, such shares of such Capital Stock or such
American Depositary Receipts. Settlement of Notes tendered for conversion to which Additional Shares shall be added to the Conversion Rate as provided in this subsection (e) shall be settled pursuant to Section 12.02(e). For purposes of
this subsection (e), a conversion shall be deemed to be “in connection with” such Make-Whole Fundamental Change if such conversion occurs on or after the Make-Whole Reference Date until the related Fundamental Change Repurchase
Date for such Make-Whole Fundamental Change or, if there is no such Fundamental Change Repurchase Date, 30 Scheduled Trading Days following the Make-Whole Reference Date, but in no event later than the


  
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second Scheduled Trading Day prior to the Maturity of the Notes. The Company will notify Holders and the Trustee in writing of the occurrence of any Make-Whole Fundamental Change applicable to
this subsection (e) on the Make-Whole Reference Date. 
  
 (i) The number of Additional Shares by which the Conversion Rate will be increased in the event of a Make-Whole Fundamental Change shall be determined by the Company by reference to the table attached as
Schedule A hereto, based on the Make-Whole Reference Date and the Stock Price; provided that, for purposes of determining the number of Additional Shares, the Make-Whole Reference Date of a transaction described in clause
(1) or (2) of the definition of Fundamental Change shall be deemed to be the earlier of (x) the date on which such transaction occurs or becomes effective and (y) the date of the first public announcement of such transaction by
the Company or the counterparty to the transaction; provided, that if the actual Stock Price is between two Stock Price amounts in the table or the Make-Whole Reference Date is between two Make-Whole Reference Dates in the table, the number
of Additional Shares by which the Conversion Rate will be increased shall be determined by a straight-line interpolation between the number of Additional Shares set forth for the next higher and next lower Stock Price amounts and the two nearest
Make-Whole Reference Dates, as applicable, based on a 365-day year; provided, further, that if (1) the Stock Price is greater than $46.50 per share of Common Stock (subject to adjustment in accordance with clause (ii) below), no
adjustments will be made in the Conversion Rate, and (2) the Stock Price is less than $16.50 per share (subject to adjustment in accordance with clause (ii) below), no adjustments will be made in the Conversion Rate. Notwithstanding the
foregoing, in no event shall the Conversion Rate exceed 60.6061 shares per $1,000 in Original Principal Amount of Notes (subject to adjustment in the same manner as set forth in Section 12.04). In addition, if Holders convert their Notes prior
to any applicable Make-Whole Reference Date, and the related Make-Whole Fundamental Change does not occur, Holders will not be entitled to an increased Conversion Rate in connection with such conversion. 

 
 (ii) The Stock Prices set forth in the first
row of the tables in Schedule A hereto shall be adjusted by the Company as of any date on which the Conversion Rate of the Notes is adjusted (except pursuant to this Section 12.01(e)). The adjusted Stock Prices shall equal the Stock
Prices applicable immediately prior to such adjustment, multiplied by a fraction, the numerator of which is the applicable Conversion Rate in effect immediately prior to the adjustment giving rise to the Stock Price adjustment and the denominator of
which is the Conversion Rate as so adjusted. The number of Additional Shares within the table shall be adjusted in the same manner as the Conversion Rate as set forth in Section 12.04 (other than by operation of an adjustment to the Conversion
Rate by adding Additional Shares). 
  

(f) In the event the Company calls the Notes for redemption pursuant to Section 11.01, the Notes shall be convertible
until 5:00 p.m., New York City time, on the Business Day preceding the applicable Redemption Date (after which time the Holders’ right to convert will expire unless the Company defaults in the payment of the applicable Redemption Price).


  
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 SECTION 12.02 Exercise of Conversion Privilege. 

 
 (a) The Company shall satisfy the Conversion Obligation by
delivering, as applicable: 
  
 (i)
on or before the third Business Day immediately following the Conversion Date, a number of shares of Common Stock equal to (i) (A) the aggregate Original Principal Amount of Notes to be converted, divided by (B) 1,000 multiplied by
(ii) the Conversion Rate in effect on the relevant Conversion Date; 
  
 (ii) on the third Business Day immediately following the last day of the related Observation Period, for each $1,000 in Original Principal Amount of Notes tendered for conversion, cash in an amount equal
to the sum of the Daily Conversion Values for each of the 30 VWAP Trading Days during the related Observation Period; or 
  

(iii) on the third Business Day immediately following the last day of the related Observation Period, for each $1,000 in
Original Principal Amount of Notes tendered for conversion, cash and shares of Common Stock, if any, equal to the sum of the Daily Settlement Amounts for each of the 30 VWAP Trading Days during the related Observation Period, 

 
 in each case subject, if applicable, to
Section 12.02(c) and Section 12.03 hereof. The applicable settlement method for any particular conversion of Notes (pursuant to clause (i), (ii) or (iii) above) shall be determined pursuant to Section 12.02(b). 

 
 (b) Prior to the 35th Scheduled Trading Day prior to the
Maturity Date, the Company may elect to settle conversions in respect of the Conversion Obligation pursuant to clause (i), (ii) or (iii) of Section 12.02(a) (or, if the Company has made the Net Share Settlement Election on or prior to
the applicable Conversion Date, clause (ii) or (iii) of Section 12.02(a)) by providing notice (a “Consideration Notice”) to the converting Holders through the Trustee (by requesting in writing that the Trustee provide
the Consideration Notice) of the applicable settlement method no later than the second Business Day immediately following the related Conversion Date or by making the Net Share Settlement Election. If the Consideration Notice designates settlement
pursuant to clause (iii) of Section 12.02(a), it will state the Specified Dollar Amount. If the Company does not provide a Consideration Notice in respect of a conversion and has not made the Net Settlement Election, conversion of the
applicable Notes will be settled pursuant to clause (i) of Section 12.02(a). 
  

At any time prior to the 35th Scheduled Trading Day prior to the Maturity Date, the Company may deliver a one-time
Consideration Notice to the Holders designating the settlement method (clause (i), (ii) or (iii) of Section 12.02(a) or, if the Company has made the Net Share Settlement Election, clause (ii) or (iii) of
Section 12.02(a)) for all conversions that occur on or after the 35th Scheduled Trading Day prior to the Maturity Date. For conversions that occur on or after the 35th Scheduled Trading Day prior to the Maturity Date, 

 
 (1) if the Company has not delivered the
one-time Consideration Notice referred to in this Section 12.02(b) and has not made the Net Share Settlement Election, conversion of the applicable Notes will be settled in accordance with clause (i) of Section 12.02(a); and


  
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 (2) if the Company has not delivered the one-time Consideration Notice
referred to in this Section 12.02(b) and has made the Net Share Settlement Election, conversion of the applicable Notes will be settled in accordance with clause (iii) of Section 12.02(a), and the Specified Dollar Amount for all such
conversions will be deemed to be the Accreted Principal Amount as of the Maturity Date. 
  

At any time prior to the 35th Scheduled Trading Day prior to the Maturity Date, the Company may
deliver a one-time irrevocable notice to the Holders electing to settle all conversions of the Notes from the date of such notice pursuant to either clause (ii) or (iii) of Section 12.02(a) (the “Net Share Settlement
Election”). If the Company has made the Net Share Settlement Election and elected to settle all conversions pursuant to clause (iii) above, the notice of such Net Share Settlement Election shall state the Specified Dollar Amount
applicable to all conversions of such Notes, which shall be at least the Accreted Principal Amount of such Notes as of the Conversion Date, provided that the Specified Dollar Amount applicable to all conversions of such Notes converted on or
after the 35th Scheduled Trading Day prior to the Maturity
Date shall be at least the Accreted Principal Amount of such Notes as of the Maturity Date. Upon making the Net Share Settlement Election, the Company will issue a Press Release or post such information on its website, or otherwise publicly disclose
such information, and will provide written notice to the Holders in the manner contemplated by this Supplemental Indenture, including through the facilities of the DTC. 

 
 The Company will settle all conversions by
Holders converting on the same Trading Day in the same manner. Except for all conversions that occur on or after the 35th Scheduled Trading Day prior to the Maturity Date and, if the Company has made the Net Share Settlement Election (to the extent
such election restricts the method of conversion), all conversions that occur on or after the date of such Net Share Settlement Election, the Company will have no obligation to settle Conversion Obligations arising on different Trading Days in the
same manner. 
  
 (c) Notwithstanding
any of the foregoing to the contrary, in lieu of settling the Conversion Obligation in the manner set forth in Section 12.02(a) above, the Company may elect (the “Exchange Election”) to direct the Conversion Agent in writing to
surrender, on or prior to the second Business Day following the Conversion Date, Notes tendered for conversion to a financial institution designated by the Company (the “Financial Institution”) for exchange in lieu of conversion. In
order to accept any Notes surrendered for conversion, the Financial Institution must agree to timely deliver, in exchange for such Notes, the shares of Common Stock and/or cash which would otherwise be due upon conversion as set forth in
Section 12.02(a) (the “Conversion Consideration”). If the Company makes the Exchange Election, the Company will, by the close of business on the second Business Day following the relevant Conversion Date, notify Holders
surrendering Notes for conversion that the Company has made the Exchange Election and will notify the Financial Institution of the Conversion Consideration to be delivered pursuant to Sections 12.02(a) and (b) and the relevant deadline for
delivery of the Conversion Consideration. Any Notes exchanged by the Financial Institution will remain outstanding. If the Financial Institution agrees to accept Notes for exchange but does not timely deliver the related Conversion Consideration, or
if such Financial Institution does not accept such Notes for exchange, the Company will deliver the Conversion Consideration as if the Company had not made the Exchange Election. 

  
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 (d) Before any Holder of a Note shall be entitled to convert the same as set
forth above, such Holder shall (1) in the case of a Global Note, comply with the procedures of the Depositary in effect at that time and, if required, pay funds equal to Interest payable on the next Interest Payment Date to which such Holder is
not entitled as set forth in subsection (i) of this Section 12.02(a) and, if required, pay all taxes or duties, if any, in connection therewith and (2) in the case of a Note issued in certificated form, (A) complete and manually
sign and deliver an irrevocable written notice to the Conversion Agent in the form set forth under Section 2.03 (or a facsimile thereof) (a “Notice of Conversion”) at the office of the Conversion Agent and shall state in
writing therein the Accreted Principal Amount of Notes to be converted and the name or names (with addresses) in which such Holder wishes the certificate or certificates for any shares of Common Stock, if any, to be delivered upon settlement of the
Conversion Obligation to be registered, (B) surrender such Notes, duly endorsed to the Company or in blank (and accompanied by appropriate endorsement and transfer documents), at the office of the Conversion Agent, (C) if required, pay
funds equal to Interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in subsection (i) of Section 12.02(a), and (D) if required, pay all taxes or duties, if any, in connection therewith.
As used herein, “Conversion Date” shall mean the date that the Holder has complied with the requirements set forth in this subsection (d). 
  

No Notice of Conversion with respect to any Notes may be tendered by a Holder thereof if such Holder has also tendered a
Fundamental Change Repurchase Notice and not validly withdrawn such Fundamental Change Repurchase Notice in accordance with the applicable provisions of Section 11.09. 

 
 If more than one Note shall be surrendered
for conversion at one time by the same Holder, the Conversion Obligation with respect to such Notes, if any, that shall be payable upon conversion shall be computed on the basis of the aggregate Accreted Principal Amount of the Notes (or specified
portions thereof to the extent permitted thereby) so surrendered. 
  
 (e) Delivery of the amounts owing in satisfaction of the Conversion Obligation shall be made by the Company in no event later than the date specified in subsection (a) of this Section 12.02,
except to the extent specified in subsection (b) of this Section 12.02. The Company shall make such delivery by issuing, or causing to be issued, and delivering to such Holder, or such Holder’s nominee or nominees, certificates or a
book-entry transfer through the Depositary for the number of full shares of Common Stock to which such Holder shall be entitled as part of such Conversion Obligation (together with any cash in lieu of fractional shares). 

 
 (f) In case any Note shall be surrendered for partial
conversion, the Company shall execute and the Trustee shall, as provided in a Company Order, authenticate and deliver to or upon the written order of the Holder of the Note so surrendered, without charge to such Holder, a new Note or Notes in
authorized denominations in an aggregate Accreted Principal Amount equal to the unconverted portion of the surrendered Notes. 
  

(g) If a Holder submits a Note for conversion, the Company shall pay all documentary, stamp or similar issue or transfer tax due, if any,
which may be imposed by the United States or any political subdivision thereof or taxing authority thereof or therein with respect to the issuance of shares of Common Stock, if any, upon the conversion. However, the Holder shall pay any such tax
which is 

  
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due because the Holder requests any shares of Common Stock to be issued in a name other than the Holder’s name. The Company may refuse to deliver the certificates representing the shares of
Common Stock being issued in a name other than the Holder’s name until the Company receives a sum sufficient to pay any tax which will be due because the shares are to be issued in a name other than the Holder’s name. Nothing herein shall
preclude any tax withholding required by law or regulations. 
  
 (h) Except as provided in Section 12.04, no adjustment shall be made for dividends on any shares issued upon the conversion of any Note as provided in this Article 12. 

 
 (i) Upon the conversion of an interest in a Global Note, the
Trustee, or the Custodian at the direction of the Trustee, shall make a notation on such Global Note as to the reduction in the principal amount represented thereby. The Company shall notify the Trustee in writing of any conversion of Notes effected
through any Conversion Agent other than the Trustee. 
  
 (j) Upon conversion, a Holder shall not receive any separate cash payment for accrued and unpaid Interest except as set forth below. The Company’s settlement of the Conversion Obligation as described
above shall be deemed to satisfy its obligation to pay the principal amount of the Notes and accrued and unpaid Interest to, but not including, the Conversion Date. As a result, accrued and unpaid Interest on the Notes to, but not including, the
Conversion Date shall be deemed to be paid in full rather than cancelled, extinguished or forfeited. Notwithstanding the preceding sentence, if Notes are converted after 5:00 p.m., New York City time, on a Regular Record Date, Holders of such Notes
as of 5:00 p.m., New York City time, on such Regular Record Date shall receive the Interest payable on such Notes on the corresponding Interest Payment Date notwithstanding the conversion. Notes surrendered for conversion during the period from 5:00
p.m., New York City time, on any Regular Record Date to 9:00 a.m., New York City time, on the corresponding Interest Payment Date must be accompanied by payment of an amount in cash equal to the Interest payable, on such Interest Payment Date, on
the Notes so converted; provided, however, that no such payment need be made (i) if the Company has specified a Fundamental Change Repurchase Date that is after a Regular Record Date and on or prior to the corresponding Interest
Payment Date; or (ii) to the extent of any overdue Interest remains unpaid at the time of conversion with respect to such Note. Except as described above, no payment or adjustment shall be made for accrued Interest on converted Notes. The
Company shall not be required to convert any Notes that are surrendered for conversion without payment of Interest as required by this Section 12.02(j). The Conversion Rate will not be adjusted for accrued and unpaid Interest or accreted
principal in excess of the $1,000 Original Principal Amount of the Notes. 
  
 SECTION 12.03 Fractions of Shares. 
  

No fractional shares of Common Stock shall be issued upon conversion of any Note or Notes. If more than one Note shall be
surrendered for conversion at one time by the same Holder, the number of full shares which shall be issuable upon conversion thereof shall be computed on the basis of the aggregate Accreted Principal Amount of the Notes (or specified portions
thereof) so surrendered. Instead of any fractional share of Common Stock that would otherwise be issuable upon conversion of any Note or Notes (or specified portions thereof), the Company shall calculate and pay a cash adjustment in respect of such
fraction (calculated to the 

  
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nearest 1/100th of a share) based on the Daily VWAP on (x) the last VWAP Trading Day of the applicable Observation Period in the case of conversions following any Net Share Settlement
Election or conversions settled in accordance with clause (iii) of Section 12.02(a) above and (y) the Conversion Date (or, if the Conversion Date is not a Trading Day, the next following Trading Day) if the Company elects to settle in
accordance with clause (i) of Section 12.02(a) above. 
  
 SECTION 12.04 Adjustment of Conversion Rate. 
  

The Conversion Rate shall be adjusted from time to time by the Company as follows; provided that the Company shall
not make any adjustments to the Conversion Rate if Holders of the Notes participate (as a result of holding the Notes, and at the same time as holders of the Common Stock participate) in any of the transactions described below as if such Holders
held a number of shares of Common Stock equal to the applicable Conversion Rate, multiplied by the Original Principal Amount (expressed in thousands) of Notes held by such Holders, without having to convert their Notes: 

 
 (a) In case the Company shall issue shares of Common Stock as
a dividend or distribution on shares of Common Stock, or shall effect a share split or share combination, the Conversion Rate shall be adjusted based on the following formula: 

 

							
		 	CR’ = CR0 ×	  	 OS’
	  	
	 	  	OS0	  	

  
 where, 

 
 CR0 = the Conversion Rate in effect immediately prior to the close of
business on the Ex-Date for such dividend or distribution or the effective date of such share split or combination, as the case may be; 
  

CR’ = the Conversion Rate in effect immediately after the close of business on the Ex-Date for such dividend or distribution or the
effective date of such share split or combination, as the case may be; 
  
 OS0 = the number
of shares of Common Stock outstanding immediately prior to the Ex-Date for such dividend or distribution or the effective date of such share split or combination, as the case may be; and 
  
 OS’ = the number of shares of Common Stock that will be outstanding as of the Ex-Date for such dividend or
distribution and immediately after giving effect to such dividend or distribution or immediately after the effective date of such share split or combination, as the case may be. 

 
 Such adjustment shall become effective
immediately after the close of business on the Ex-Date fixed for such dividend or distribution, or the effective date for such share split or share combination. If any dividend or distribution of the type described in this Section 12.04(a) is
declared but not so paid or made, or the outstanding shares of Common Stock are not split or combined, as the case may be, the Conversion Rate shall be immediately readjusted, effective as 

  
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of the date the Board of Directors determines not to pay such dividend or distribution, or split or combine the outstanding shares of Common Stock, as the case may be, to the Conversion Rate that
would then be in effect if such dividend, distribution, share split or share combination had not been declared. 
  

(b) In case the Company shall distribute to all or substantially all holders of its outstanding shares of Common Stock any rights or
warrants entitling them for a period expiring not more than 60 calendar days after the Ex-Date of such distribution to subscribe for or purchase shares of Common Stock at a price per share less than the Last Reported Sale Price of the Common Stock
on the Trading Day immediately preceding the declaration date of such distribution, the Conversion Rate shall be adjusted based on the following formula; provided that the Conversion Rate will be readjusted to the extent that such rights or
warrants are not exercised prior to their expiration: 
  

							
		 	CR’ = CR0 ×	  	 (OS0 + X)
	  	
	 	  	(OS0 + Y)	  	

  
 where, 

 
 CR0 = the Conversion Rate in effect immediately prior to the close of
business on the Ex-Date for such distribution; 
  

CR’ = the Conversion Rate in effect immediately after the close of business on the Ex-Date for such distribution; 

 
 OS0 = the number of shares of Common Stock outstanding immediately prior to
the Ex-Date for such distribution; 
  
 X = the total
number of shares of Common Stock issuable pursuant to such rights or warrants; and 
  
 Y = the number of shares of Common Stock equal to the aggregate price payable to exercise such rights or warrants divided by the average of the Daily VWAP of Common Stock over the 10 consecutive VWAP
Trading Day period ending on the VWAP Trading Day immediately preceding the Ex-Date for such distribution. 
  

Such adjustment shall be successively made whenever any such rights or warrants are distributed and shall become effective
immediately after the close of business on the Ex-Date for such distribution. The Company shall not issue any such rights or warrants in respect of shares of the Common Stock held in treasury by the Company. To the extent that shares of the Common
Stock are not delivered after the expiration of such rights or warrants, the Conversion Rate shall be readjusted to the Conversion Rate that would then be in effect had the adjustments made upon the issuance of such rights or warrants been made on
the basis of delivery of only the number of shares of Common Stock actually delivered. If such rights or warrants are not so issued, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such Ex-Date
for such distribution had not been fixed. 

  
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 In determining whether any rights or warrants entitle the holders to
subscribe for or purchase shares of Common Stock at less than such Last Reported Sale Price, and in determining the aggregate offering price of such shares of Common Stock, there shall be taken into account any consideration received by the Company
for such rights or warrants and any amount payable on exercise or conversion thereof, the value of such consideration, if other than cash, to be determined by the Board of Directors. 
  
 (c) In case the Company shall, by dividend or otherwise, distribute to all or substantially all holders of its
Common Stock shares of any class of Capital Stock of the Company, evidences of its Indebtedness or other assets or property of the Company (excluding (i) dividends and distributions covered by subsections (a), (b) or (d) of this
Section 12.04 and distributions described below in this subsection (c) with respect to Spin-Offs) (any of such shares of Capital Stock, Indebtedness, or other asset or property hereinafter in this subsection (c) called the
“Distributed Property”), then, in each such case the Conversion Rate shall be adjusted based on the following formula: 
  

							
		 	CR’ = CR0 ×	  	 SP0
	  	
	 	  	SP0 – FMV	  	

  
 where, 

 
 CR0 = the Conversion Rate in effect immediately prior to the close of
business on the Ex-Date for such distribution; 
  

CR’ = the Conversion Rate in effect immediately after the close of business on the Ex-Date for such distribution; 

 
 SP0 = the average of the Daily VWAP of Common Stock over the ten
(10) consecutive VWAP Trading Day period ending on the VWAP Trading Day immediately preceding the Ex-Date for such distribution; and 
  

FMV = the fair market value as determined by the Board of Directors or a committee thereof of the Distributed Property with respect to
each outstanding share of Common Stock on the Ex-Date for such distribution. 
  

Such adjustment shall become effective immediately after the close of business on the Ex-Date for such
distribution; provided that if “FMV” as set forth above is equal to or greater than “SP0” as set forth above, in lieu of the foregoing adjustment, adequate provision shall be made so that each Holder has the right to receive, for each $1,000 in principal amount of Notes, the amount of
Distributed Property such Holder would have received had such Holder owned a number of shares of Common Stock equal to the Conversion Rate on the Ex-Date for such distribution, without being required to convert the Notes. If such distribution is not
so paid or made, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. If the Board of Directors determines “FMV” for purposes of this
Section 12.04(c) by reference to the actual or when issued trading market for any securities, it must in doing so consider the prices in such market over the same period used in computing the Last Reported Sale Prices of the Common Stock over
the ten consecutive Trading Day period ending on the Trading Day immediately preceding the Ex-Date for such distribution. 

  
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 With respect to an adjustment pursuant to this subsection (c) where
there has been a payment of a dividend or other distribution on the Common Stock, in shares of Capital Stock of any class or series, or similar equity interest, of or relating to a Subsidiary or other business unit (a “Spin-Off”),
the Conversion Rate in effect immediately before 5:00 p.m., New York City time, on the 10th Trading Day immediately following, and including, the effective date of the Spin-Off shall be increased based on the following formula: 

 

							
		 	CR’ = CR0 ×	  	 FMV0 + MP0
	  	
	 	  	MP0	  	

  
 where, 

 
 CR0 = the Conversion Rate in effect immediately prior to the close of
business on the 10th Trading Day immediately following the effective date of the Spin-Off; 
  
 CR’ = the Conversion Rate in effect immediately after the close of business on the 10th Trading Day immediately following the effective date of the Spin-Off; 

 
 FMV0 = the average of the Last Reported Sale Prices of the Capital Stock or
similar equity interest distributed to holders of Common Stock applicable to one share of Common Stock over the first 10 consecutive VWAP Trading Day period immediately following, and including, the effective date of the Spin-Off; and 

 
 MP0 = the average of the Daily VWAP of Common Stock over the first 10
consecutive VWAP Trading Day period immediately following, and including, the effective date of the Spin-Off. 
  

Such adjustment to the Conversion Rate under this subsection (c) shall occur on the 10th Trading Day from, and
including, the effective date of the Spin-Off; provided that for any conversion within the 10 Trading Days immediately following, and including, the effective date of any Spin-Off, the Conversion Rate shall be adjusted based on the number of
Trading Days between the effective date of such Spin-Off and the Conversion Date. 
  
 Rights or warrants distributed by the Company to all holders of Common Stock, entitling the holders thereof to subscribe for or purchase shares of the Company’s Capital Stock, including Common Stock
(either initially or under certain circumstances), which rights or warrants, until the occurrence of a specified event or events (“Trigger Event”): (i) are deemed to be transferred with such shares of Common Stock;
(ii) are not exercisable; and (iii) are also issued in respect of future issuances of Common Stock, shall be deemed not to have been distributed for purposes of this Section 12.04 (and no adjustment to the Conversion Rate under this
Section 12.04 shall be required) until the occurrence of the earliest Trigger Event, whereupon such rights and warrants shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be
made under this subsection (c). If any such rights or warrants are subject to events, upon the occurrence of which such rights or warrants become exercisable to 

  
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purchase different securities, evidences of Indebtedness or other assets, then the date of the occurrence of any and each such event shall be deemed to be the date of distribution and record date
with respect to new rights or warrants with such rights (and a termination or expiration of the existing rights or warrants without exercise by any of the holders thereof). In addition, in the event of any distribution (or deemed distribution) of
rights or warrants, or any Trigger Event or other event (of the type described in the preceding sentence) with respect thereto that was counted for purposes of calculating a distribution amount for which an adjustment to the Conversion Rate under
this Section 12.04 was made, (1) in the case of any such rights or warrants that shall all have been redeemed or repurchased without exercise by any holders thereof, the Conversion Rate shall be readjusted upon such final redemption or
repurchase to give effect to such distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share redemption or repurchase price received by a holder or holders of Common Stock with respect to such
rights or warrants (assuming such holder had retained such rights or warrants), made to all holders of Common Stock as of the date of such redemption or repurchase, and (2) in the case of such rights or warrants that shall have expired or been
terminated without exercise by any holders thereof, the Conversion Rate shall be readjusted as if such rights and warrants had not been issued. 
  

For purposes of this subsection (c) and subsections (a) and (b) of this Section 12.04, any dividend or
distribution to which this subsection (c) is applicable that also includes shares of Common Stock to which subsection (a) of this Section 12.04 applies or rights or warrants to subscribe for or purchase shares of Common Stock to which
subsection (a) or (b) of this Section 12.04 applies (or both), shall be deemed instead to be (1) a dividend or distribution of the evidences of Indebtedness, assets or shares of Capital Stock other than such shares of Common
Stock or rights or warrants to which this subsection (c) applies (and any Conversion Rate adjustment required by this subsection (c) with respect to such dividend or distribution shall then be made), immediately followed by (2) a
dividend or distribution of such shares of Common Stock or such rights or warrants (and any further Conversion Rate adjustment required by subsections (a) and (b) of this Section 12.04 with respect to such dividend or distribution
shall then be made), except (A) the Ex-Date of such dividend or distribution shall under this subsection (c) be substituted as the “Ex-Date” within the meaning of subsection (a) and subsection (b) and (B) any
shares of Common Stock included in such dividend or distribution shall not be deemed “outstanding immediately prior to the Ex-Date for such dividend or distribution or immediately prior to the effective date of such share split or combination,
as the case may be” within the meaning of subsection (a) or “outstanding immediately prior to the Ex-Date for such distribution” within the meaning of subsection (b). 
  
 (d) In case the Company shall pay any cash dividends or distributions to all or substantially all holders of
its Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

							
		 	CR’ = CR0 ×	  	 SP0
	  	
	 	  	SP0 - C	  	


  
 71 









 where, 

 
 CR0 = the Conversion Rate in effect immediately prior to the close of
business on the Ex-Date for such distribution; 
  

CR’ = the Conversion Rate in effect immediately after the close of business on the Ex-Date for such distribution; 

 
 SP0 = the average of the Daily VWAP of Common Stock for the 10 consecutive
VWAP Trading Day period immediately preceding the Ex-Date for such distribution; and 
  
 C = the amount in cash per share the Company distributes to holders of Common Stock in such distribution. 
  

Such adjustment shall become effective immediately after the close of business on the Ex-Date for such
dividend or distribution; provided that if the portion of the cash so distributed applicable to one share of the Common Stock is equal to or greater than SP0 as set forth above, in lieu of the foregoing adjustment, adequate provision shall be made so that each Holder shall
receive on the date on which such cash dividend is distributed to holders of Common Stock, for each $1,000 in principal amount of Notes, the amount of cash such Holder would have received had such Holder owned a number of shares equal to the
Conversion Rate on the Ex-Date for such distribution, without being required to convert the Notes. If such dividend or distribution is not so paid or made, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in
effect if such dividend or distribution had not been declared. 
  
 For the avoidance of doubt, for purposes of this subsection (d), in the event of any reclassification of the Common Stock, as a result of which the Notes become convertible into more than one class of
Common Stock, if an adjustment to the Conversion Rate is required pursuant to this subsection (d), references in this subsection (d) to one share of Common Stock or Daily VWAP of one share of Common Stock shall be deemed to refer to a unit or
to the price of a unit consisting of the number of shares of each class of Common Stock into which the Notes are then convertible equal to the numbers of shares of such class issued in respect of one share of Common Stock in such reclassification.
The above provisions of this paragraph shall similarly apply to successive reclassifications. 
  
 (e) In case the Company or any of its Subsidiaries make a payment in respect of a tender offer or exchange offer for all or any portion of the Common Stock, to the extent that the cash and value of any
other consideration included in the payment per share of Common Stock exceeds the Daily VWAP of the Common Stock on the VWAP Trading Day next succeeding the last date on which tenders or exchanges may be made pursuant to such tender or exchange
offer, the Conversion Rate shall be increased based on the following formula: 
  

			
	 CR’ = CR0 ×
	  	    AC + (SP’ × OS’)    
	  	          OS0 × SP’

  

where, 
  

CR0 = the Conversion Rate in effect on the date such tender or exchange offer expires; 

  
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 CR’ = the Conversion Rate in effect on the day next succeeding the date such tender or
exchange offer expires; 
  
 AC = the aggregate value
of all cash and any other consideration as determined by the Board of Directors or a committee thereof paid or payable for shares purchased in such tender or exchange offer; 

 
 OS0 = the number of shares of Common Stock outstanding immediately prior to
the date such tender or exchange offer expires; 
  

OS’ = the number of shares of Common Stock outstanding immediately after the date such tender or exchange offer expires (after giving
effect to such tender offer or exchange offer); and 
  
 SP’ = the Last Reported Sale Price of Common Stock on the Trading Day next succeeding the date such tender or exchange offer expires. 
  
 Such adjustment shall become effective immediately after close of business on the Trading Day
next succeeding the date such tender or exchange offer expires. If the Company or its Subsidiary is obligated to purchase shares of Common Stock pursuant to any such tender or exchange offer, but the Company or its Subsidiary is permanently
prevented by applicable law from effecting all or any such purchases or all or any portion of such purchases are rescinded, the Conversion Rate shall again be adjusted to be the Conversion Rate that would then be in effect if such tender or exchange
offer had not been made or had only been made in respect of the purchases that had been effected. 
  

If the application of any of the foregoing formulas (other than in respect of a share combination) would result in a
decrease in the Conversion Rate, no adjustment to the Conversion Rate will be made. 
  

For purposes of this Section 12.04 the term “record date” shall mean, with respect to any dividend,
distribution or other transaction or event in which the holders of Common Stock have the right to receive any cash, securities or other property or in which the Common Stock (or other applicable security) is exchanged for or converted into any
combination of cash, securities or other property, the date fixed for determination of shareholders entitled to receive such cash, securities or other property (whether such date is fixed by the Board of Directors or by statute, contract or
otherwise). 
  
 (f) (i)In addition to those increases
required by subsections (a), (b), (c), (d) and (e) of this Section 12.04, and to the extent permitted by applicable law and the rules of the NASDAQ Global Select Market or any other securities exchange on which the Common Stock is
then listed, the Company from time to time may increase the Conversion Rate by any amount for a period of at least 20 Business Days if the Board of Directors determines that such increase would be in the Company’s best interest. If the Company
makes such determination, it will be conclusive and the Company will notify the Holders of the Notes and the Trustee of the increased Conversion Rate and the period during which it will be in effect at least 15 calendar days prior to the date the
increased Conversion Rate takes effect, in accordance with applicable law. The Company may also, but is not required to, 

  
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increase the Conversion Rate to avoid or diminish any income tax to holders of Common Stock or rights to purchase Common Stock in connection with a dividend or distribution of shares or rights to
acquire shares or similar event. The Company shall not increase the Conversion Rate pursuant to this Section 12.04(f)(i), if such increase would cause the Company to be in violation of Rule 5635 of the NASDAQ Stock Market or any successor
provision thereto, with respect to requirements of obtaining shareholder approval prior to the issuance of securities. 
  

(ii) If the Company has in effect a rights plan upon a conversion of the Notes into Common Stock and the rights have not
separated from the Common Stock, Holders will receive, upon a conversion of the Notes in respect of which the Company is required to deliver shares of Common Stock, in addition to such shares of Common Stock, rights under the Company’s rights
plan. If prior to any conversion, the rights have separated from the Common Stock, the Conversion Rate will be adjusted at the time of separation as if the Company had distributed to all holders of Common Stock, capital stock, evidences of
indebtedness or other assets or property pursuant to Section 12.02(d) hereof, subject to readjustment upon the subsequent expiration, termination or redemption of such rights. If the Company’s rights plan existing at the date of this
Supplemental Indenture is terminated, no adjustment in the Conversion Rate will be required upon issuance of rights under any replacement plan. 
  

(g) Except as described in this Section 12.04 or in Section 12.01(e), the Company will not adjust the Conversion Rate. Without
limiting the foregoing, no adjustment to the Conversion Rate need be made: 
  
 (i) upon the issuance of any shares of Common Stock pursuant to any present or future plan providing for the reinvestment of dividends or interest payable on securities of the Company and the investment
of additional optional amounts in shares of Common Stock under any plan; 
  
 (ii) upon the issuance of any shares of Common Stock or options or rights to purchase or acquire those shares of Common Stock pursuant to any present or future employee, director or consultant benefit
plan or program of or assumed by the Company or any of its Subsidiaries; 
  
 (iii) upon the issuance of any shares of Common Stock pursuant to any option, warrant, right or exercisable, exchangeable or convertible security not described in clause (ii) above and outstanding as
of the date of this Supplemental Indenture; 
  
 (iv) for a change in the par value of the Common Stock; 
  

(v) for accrued and unpaid Interest; 

 
 (vi) for accreted principal in excess of the
$1,000 Original Principal Amount of the Notes; or 
  
 (vii) as a result of a tender offer solely to holders of fewer than 100 shares of the Common Stock. 

  
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 (h) All calculations and other determinations under this Article 12 shall be made by the
Company and shall be made to the nearest cent or to the nearest one-ten thousandth (1/10,000) of a share, as the case may be. No adjustment shall be made to the Conversion Rate unless such adjustment would require a change of at least 1% in the
Conversion Rate then in effect at such time. The Company shall carry forward any adjustments that are less than 1% of the Conversion Rate and make such carried forward adjustments, regardless of whether the aggregate adjustment is less than 1%, to
any Notes that are converted upon such conversion. 
  

(i) In any case in which this Section 12.04 provides that an adjustment shall become effective immediately after (1) the Ex-Date
for an event or (2) the last date on which tenders or exchanges may be made pursuant to any tender or exchange offer pursuant to subsection (e) of this Section 12.04 (each an “Adjustment Determination Date”), the
Company may elect to defer until the occurrence of the applicable Adjustment Event (as hereinafter defined) (x) issuing to the Holder of any Note converted after such Adjustment Determination Date and before the occurrence of such Adjustment
Event, the additional cash and, if applicable, shares of Common Stock or other securities issuable upon such conversion by reason of the adjustment required by such Adjustment Event over and above the amounts deliverable upon such conversion before
giving effect to such adjustment and (y) paying to such Holder any amount in cash in lieu of any fraction pursuant to Section 12.03. For purposes of this subsection (i), the term “Adjustment Event” shall mean: 

 
 (i) in any case referred to in clause
(1) hereof, the date any dividend or distribution of Common Stock, shares of Capital Stock, evidences of Indebtedness, other assets or property or cash is paid or made, the effective date of any share split or combination or the date of
expiration of any rights or warrants; and 
  
 (ii) in any case referred to in clause (2) hereof, the date a sale or exchange of Common Stock pursuant to such tender or exchange offer is consummated and becomes irrevocable. 

 
 (j) For purposes of this Section 12.04, the number of
shares of Common Stock at any time outstanding shall not include shares held in the treasury of the Company but shall include shares issuable in respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 

 
 (k) For the avoidance of doubt, if a Holder converts Notes
prior to the effective date of a Fundamental Change, and the Fundamental Change does not occur, the Holder shall not be entitled to Additional Shares in connection with such conversion. 
  
 (l) With respect to a conversion of Notes pursuant to this Article 12, on the date the Shares issuable upon
conversion of the Notes are delivered to the converting Holder pursuant to Section 12.02(a) (the “Delivery Date”), the Person in whose name any certificate representing any shares of Common Stock issuable upon such conversion
is registered shall be treated as a stockholder of record of the Company on such Delivery Date. On and after the Delivery Date with respect to a conversion of Notes pursuant hereto, all rights of the Holders of such Notes shall terminate. A Holder
of a Note is not entitled, as such, to any rights of a holder of Common Stock unless and until such Holder converts such Note and receives shares of Common Stock in respect of such conversion on the Delivery Date with respect to such conversion.


  
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 (m) Whenever any provision of this Article 12 requires a calculation of Last Reported Sale
Prices over a span of multiple days, the Company shall make appropriate adjustments to account for any adjustment to the Conversion Rate that becomes effective, or any event requiring an adjustment to the Conversion Rate where the Ex-Date of the
event occurs, at any time during the period from which such calculation is to be calculated; provided that such adjustments shall only be made to the Conversion Rate relating to days prior to the date that the adjustment to the Conversion
Rate becomes effective. 
  
 (n) If the effective date
of any adjustment event described in this Section 12.04 occurs during an Observation Period for any Notes, the Company shall make proportional adjustments to the number of Deliverable Shares (in the same manner as the Conversion Rate) for each
VWAP Trading Day during the portion of the Observation Period preceding the effective date of such adjustment event. 
  

SECTION 12.05 Notice of Adjustments of Conversion Rate. 
  
 Whenever the Conversion Rate is adjusted as herein provided: 

 
 (a) the Company shall compute the adjusted Conversion Rate in
accordance with Section 12.04 and shall prepare a certificate signed by the Chief Financial Officer of the Company setting forth the adjusted Conversion Rate and showing in reasonable detail the facts upon which such adjustment is based, and
such certificate shall promptly be filed with the Trustee and with each Conversion Agent (if other than the Trustee); and 
  

(b) upon each such adjustment, a notice stating that the Conversion Rate has been adjusted and setting forth the adjusted Conversion Rate
shall be required, such notice shall be provided by the Company to all Holders in accordance with Section 1.6 of the Base Indenture. 
  

Neither the Trustee nor any Conversion Agent shall be under any duty or responsibility with respect to any such
certificate or the information and calculations contained therein, except to exhibit the same to any Holder desiring inspection thereof at its office during normal business hours or in such other manner of inspection as the Trustee deems
practicable. 
  
 SECTION 12.06 Company
to Reserve Common Stock. 
  
 The
Company shall at all times reserve and keep available, free from preemptive rights, out of its authorized but unissued Common Stock, for the purpose of effecting the conversion of Notes, the full number of shares of Common Stock then issuable upon
the conversion of all Outstanding Notes. 
  

SECTION 12.07 Taxes on Conversions. 

 
 Except as provided in the next sentence, the
Company shall pay all documentary, stamp or similar issue or transfer tax due that may be payable in respect of the issue or delivery of shares of Common Stock on conversion of Notes pursuant hereto. The Company shall not, however, be required, and
the Holder shall instead be required, to pay any tax or duty that may be payable in respect of (i) income of the Holder, or (ii) any transfer involved in the issue and 

  
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delivery of shares of Common Stock in a name other than that of the Holder of the Note or Notes to be converted, and no such issue or delivery shall be made unless and until the Person requesting
such issue has paid to the Company the amount of any such tax or duty, or has established to the satisfaction of the Company that such tax or duty has been paid. 

 
 SECTION 12.08 Certain Covenants.

  
 Before taking any action which
would cause an adjustment reducing the Conversion Rate below the then par value, if any, of the shares of Common Stock issuable upon conversion of the Notes, the Company shall take all corporate action, if any, which it reasonably determines may be
necessary in order that the Company may validly and legally issue shares of such Common Stock at such adjusted Conversion Rate. 
  

The Company covenants that all shares of Common Stock issued upon conversion of Notes shall be fully paid and
non-assessable by the Company and free from all liens created by the Company. 
  
 SECTION 12.09 Cancellation of Converted Notes. 
  

All Notes delivered for conversion shall be delivered to the Trustee or its agent and canceled by the Trustee as provided
in Section 3.11. 
  
 SECTION 12.10
Provision in Case of Effect of Reclassification, Consolidation, Merger or Sale. 
  

If there shall occur (i) any Fundamental Change described in clause (2) of the definition of Fundamental Change,
(ii) any reclassification or change of the outstanding shares of Common Stock (other than a change in par value, or from par value to no par value, or from no par value to par value, or as a result of a split, subdivision or combination),
(iii) any consolidation, binding share exchange, recapitalization, reclassification, merger, combination or other similar event, or (iv) any sale or conveyance of all or substantially all of the property and assets of the Company to any
other Person, in any case as a result of which holders of Common Stock shall be entitled to receive cash, securities or other property or assets with respect to or in exchange for their shares of Common Stock (any such event described in clauses
(i) through (iv) a “Merger Event”), then: 
  
 (a) the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee (subject to the Trustee’s rights as provided herein) a supplemental indenture (which shall
comply with the Trust Indenture Act as in force at the date of execution of such supplemental indenture if such supplemental indenture is then required to so comply) permitted under Section 8.01(f) providing for the conversion and settlement of
the Notes as set forth in this Supplemental Indenture. Such supplemental indenture shall provide for adjustments which shall be as nearly equivalent as may be practicable to the adjustments provided for in this Article 12 and the Trustee may
conclusively rely on the determination by the Company of the equivalency of such adjustments. If, in the case of any Merger Event, the Reference Property includes shares of stock or other securities and assets of a company other than the successor
or purchasing company, as the case may be, in such change of control, consolidation, binding share exchange, recapitalization, reclassification, merger, 

  
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combination, sale or conveyance or Fundamental Change described in clause (2) of the definition of Fundamental Change, then such supplemental indenture shall also be executed by such other
company and shall contain such additional provisions to protect the interests of the Holders of the Notes as the Board of Directors shall reasonably consider necessary by reason of the foregoing, including to the extent required by the Board of
Directors and practicable the provisions providing for the repurchase rights set forth in Article 11. 
  

In the event a supplemental indenture is executed pursuant to this Section 12.10, the Company shall promptly file
with the Trustee an Officers’ Certificate (and the documents and information provided for in Section 9.3 of the Base Indenture) briefly stating the reasons therefore, the kind or amount of cash, securities, property or assets that will
constitute the Reference Property after any such Merger Event, any adjustment to be made with respect thereto and that all conditions precedent have been complied with, and shall promptly mail notice thereof to all Holders, and the Trustee shall be
protected in relying on such Officers’ Certificate; it being understood that the Trustee shall have no responsibility to determine the correctness of any provisions contained in any supplemental indenture executed pursuant to this
Section 12.10. 
  
 If any
securities to be provided for the purpose of conversion of Notes hereunder require registration with or approval of any governmental authority under any federal or state law before such securities may be validly issued upon conversion, each
supplemental indenture executed pursuant to this Section 12.10 shall provide that the Company or the successor or the purchasing Person, as the case may be, or if the Reference Property includes shares of stock or other securities and assets of
a company other than the successor or purchasing company, as the case may be, then such company, shall use all commercially reasonable efforts, to the extent then permitted by the rules and interpretations of the Commission (or any successor
thereto), to secure such registration or approval in connection with the conversion of Notes. 
  

Notwithstanding the provisions of Section 12.02 and Section 12.03, and subject to the provisions of
Section 12.01, at the effective time of such Merger Event, the right to convert each $1,000 in principal amount of Notes shall be changed to a right to convert such Notes by reference to the kind and amount of cash, securities, or other
property that a holder of a number of shares of Common Stock equal to the Conversion Rate immediately prior to such transaction would have owned or been entitled to receive (the “Reference Property”) such that from and after the
effective time of such transaction, a Holder shall be entitled thereafter to convert its Notes into the same type (and in the same proportion) of Reference Property, subject to the Company’s right to elect to settle conversions, in whole or in
part, in shares of Common Stock, cash or a combination of cash and shares of Common Stock, provided that if the Company makes the Net Share Settlement Election, upon conversion, Holders will receive Reference Property as follows:
(x) either (i) all cash or (ii) cash up to the Specified Dollar Amount, and (y) in lieu of the shares of Common Stock otherwise deliverable, Reference Property. The amount of consideration, and, consequently, Reference Property,
Holders receive upon conversion will be based on the Daily Conversion Values of Reference Property and the applicable Conversion Rate, as described in Section 12.02. For purposes of determining the constitution of Reference Property, the type
and amount of consideration that a holder of Common Stock would have been entitled to in the case of any Merger Event that causes the Common Stock to be converted into the right to receive more than a single type of consideration determined, based
in part upon any 

  
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form of stockholder election, such consideration will be deemed to be the weighted average of the types and amounts of consideration received by the holders of Common Stock that affirmatively
make such an election, or (ii) if no holders of Common Stock affirmatively make such an election, the types and amount of consideration actually received by such holders. The Company shall not become a party to any such transaction unless its
terms are consistent with the preceding. None of the foregoing provisions shall affect the right of a Holder to convert its Notes in accordance with the provisions of this Article 12 prior to the effective date. 

 
 (b) The Company shall cause notice of the execution of such
supplemental indenture to be mailed to each Holder, at his address appearing on the Securities Register provided for in this Supplemental Indenture, within 20 calendar days after execution thereof. Failure to deliver such notice shall not affect the
legality or validity of such supplemental indenture. 
  
 (c) The above provisions of this Section 12.10 shall similarly apply to successive Merger Events. 
  

SECTION 12.11 Company Responsible for Making Calculations. 
  
 Except as otherwise provided herein, the Company will be responsible for making all
calculations required under the Notes and this Supplemental Indenture. The Company will make these calculations in good faith and absent manifest error, these calculations will be final and binding on the Holders. The Company will provide a schedule
of such calculations to each of the Trustee and the Conversion Agent, and each of the Trustee and the Conversion Agent is entitled to conclusively rely upon the accuracy of such calculations without independent verification. The Trustee will forward
the Company’s calculations to any Holder upon the written request of such Holder. 
  
 SECTION 12.12 Responsibility of Trustee for Conversion Provisions. 
  

The Trustee and any Conversion Agent shall not at any time be under any duty or responsibility to any Holder to determine
whether any facts exist which may require any adjustment of the Conversion Rate, or with respect to the nature or extent of any such adjustment when made, or with respect to the method employed, herein or in any supplemental indenture provided to be
employed, in making the same, or whether a supplemental indenture need be entered into. Neither the Trustee nor any Conversion Agent shall be accountable with respect to the validity or value (or the kind or amount) of any Common Stock, or of any
other securities or property or cash, which may at any time be issued or delivered upon the conversion of any Notes; and it or they do not make any representation with respect thereto. Neither the Trustee nor any Conversion Agent shall be
responsible for any failure of the Company to make or calculate any cash payment or to issue, transfer or deliver any shares of Common Stock or share certificates or other securities or property or cash upon the surrender of any Note for the purpose
of conversion; and the Trustee and any Conversion Agent shall not be responsible for any failure of the Company to comply with any of the covenants of the Company contained in this Article 12. 
  
  

  
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 This instrument may be executed in any number of counterparts, each of which
so executed shall be deemed to be an original, but all such counterparts shall together constitute but one and the same instrument. 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Supplemental
Indenture to be duly executed all as of the day and year first above written. 
  

			
	HOLOGIC, INC.
		
	By:	 	 /s/ Glenn P. Muir

		 	Name: Glenn P. Muir
		 	Title: Executive Vice President, Finance and Administration, Chief Financial Officer, Assistant Treasurer and Assistant Secretary
	
	 WILMINGTON TRUST COMPANY,
 as Trustee

		
	By:	 	 /s/ Geoffrey J. Lewis

		 	Name: Geoffrey J. Lewis
		 	Title: Assistant Vice President



  
 81 









 SCHEDULE A 

 
 The following table sets forth the hypothetical “Stock
Price,” “Make-Whole Reference Date” and the adjustments to the Conversion Rate, expressed as a number of Additional Shares by which the Conversion Rate shall be increased in the event of a Fundamental Change (other than events
described in clauses (3) and (5) of the definition of a Fundamental Change), in accordance with the Supplemental Indenture: 
  

																																																					
	  	  	Stock Price	 
	 Make-Whole
 Reference Date
	  	$16.50	 	  	$19.00	 	  	$21.50	 	  	$24.00	 	  	$26.50	 	  	$29.00	 	  	$31.50	 	  	$34.00	 	  	$36.50	 	  	$39.00	 	  	$41.50	 	  	$44.00	 	  	$46.50	 
														
	 November 23, 2010
	  	 	16.3663	 	  	 	12.5995	 	  	 	9.9598	 	  	 	8.0492	 	  	 	6.6312	 	  	 	5.5474	 	  	 	4.7054	 	  	 	4.0372	 	  	 	3.4989	 	  	 	3.0605	 	  	 	2.6989	 	  	 	2.3966	 	  	 	2.1719	 
														
	 Decmber 15, 2011
	  	 	16.4892	 	  	 	12.0901	 	  	 	8.9274	 	  	 	6.8396	 	  	 	5.6347	 	  	 	4.7137	 	  	 	3.9983	 	  	 	3.4305	 	  	 	2.9731	 	  	 	2.6005	 	  	 	2.2933	 	  	 	2.0364	 	  	 	1.8456	 
														
	 Decmber 15, 2012
	  	 	16.6051	 	  	 	11.6101	 	  	 	7.9545	 	  	 	5.6997	 	  	 	4.6956	 	  	 	3.9281	 	  	 	3.3319	 	  	 	2.8588	 	  	 	2.4776	 	  	 	2.1671	 	  	 	1.9111	 	  	 	1.6970	 	  	 	1.5380	 
														
	 Decmber 15, 2013
	  	 	16.7210	 	  	 	11.1301	 	  	 	6.9816	 	  	 	4.5598	 	  	 	3.7565	 	  	 	3.1425	 	  	 	2.6655	 	  	 	2.2870	 	  	 	1.9821	 	  	 	1.7337	 	  	 	1.5289	 	  	 	1.3576	 	  	 	1.2304	 
														
	 Decmber 15, 2014
	  	 	16.8368	 	  	 	10.6500	 	  	 	6.0087	 	  	 	3.4198	 	  	 	2.8174	 	  	 	2.3569	 	  	 	1.9991	 	  	 	1.7153	 	  	 	1.4866	 	  	 	1.3003	 	  	 	1.1467	 	  	 	1.0182	 	  	 	0.9228	 
														
	 Decmber 15, 2015
	  	 	16.9527	 	  	 	10.1700	 	  	 	5.0358	 	  	 	2.2799	 	  	 	1.8782	 	  	 	1.5712	 	  	 	1.3328	 	  	 	1.1435	 	  	 	0.9910	 	  	 	0.8668	 	  	 	0.7644	 	  	 	0.6788	 	  	 	0.6152	 
														
	 Decmber 15, 2016
	  	 	17.1845	 	  	 	9.2100	 	  	 	3.0900	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 	  	 	0.0000	 








 SCHEDULE B 

 
 The following table sets forth the Accreted
Principal Amounts as of the specified dates during the period from December 15, 2016 through the Maturity Date. 
  

					
	 Date
	  	Accreted Principal Amount	 
		
	 December 15, 2016
	  	$	1,000.00	  
	 June 15, 2017
	  	$	1,010.00	  
	 December 15, 2017
	  	$	1,020.10	  
	 June 15, 2018
	  	$	1,030.30	  
	 December 15, 2018
	  	$	1,040.60	  
	 June 15, 2019
	  	$	1,051.01	  
	 December 15, 2019
	  	$	1,061.52	  
	 June 15, 2020
	  	$	1,072.14	  
	 December 15, 2020
	  	$	1,082.86	  
	 June 15, 2021
	  	$	1,093.69	  
	 December 15, 2021
	  	$	1,104.62	  
	 June 15, 2022
	  	$	1,115.67	  
	 December 15, 2022
	  	$	1,126.83	  
	 June 15, 2023
	  	$	1,138.09	  
	 December 15, 2023
	  	$	1,149.47	  
	 June 15, 2024
	  	$	1,160.97	  
	 December 15, 2024
	  	$	1,172.58	  
	 June 15, 2025
	  	$	1,184.30	  
	 December 15, 2025
	  	$	1,196.15	  
	 June 15, 2026
	  	$	1,208.11	  
	 December 15, 2026
	  	$	1,220.19	  
	 June 15, 2027
	  	$	1,232.39	  
	 December 15, 2027
	  	$	1,244.72	  
	 June 15, 2028
	  	$	1,257.16	  
	 December 15, 2028
	  	$	1,269.73	  
	 June 15, 2029
	  	$	1,282.43	  
	 December 15, 2029
	  	$	1,295.26	  
	 June 15, 2030
	  	$	1,308.21	  
	 December 15, 2030
	  	$	1,321.29	  
	 June 15, 2031
	  	$	1,334.50	  
	 December 15, 2031
	  	$	1,347.85	  
	 June 15, 2032
	  	$	1,361.33	  
	 December 15, 2032
	  	$	1,374.94	  
	 June 15, 2033
	  	$	1,388.69	  
	 December 15, 2033
	  	$	1,402.58	  
	 June 15, 2034
	  	$	1,416.60	  
	 December 15, 2034
	  	$	1,430.77	  
	 June 15, 2035
	  	$	1,445.08	  
	 December 15, 2035
	  	$	1,459.53	  
	 June 15, 2036
	  	$	1,474.12	  
	 December 15, 2036
	  	$	1,488.86	  
	 June 15, 2037
	  	$	1,503.75	  
	 December 15, 2037
	  	$	1,518.79	  








 The accreted principal amount of a note between the dates listed above will
include an amount reflecting the additional principal accretion that has accrued as of such date since the immediately preceding date in the table.